PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2czhB_

Fold library id	PDB Header	Molecule	Title
c2czhB_	PDB header: hydrolase	Chain: B: PDB Molecule: inositol monophosphatase 2;	PDBTitle: crystal structure of human myo-inositol monophosphatase 22 (impa2) with phosphate ion (orthorhombic form)

Links to external resources
Added to library: Tue Mar 16 12:56:47 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence P W E E C F Q A A V Q L A L R A G Q I I R K A L T E L V T E T D H L V E D L I I S E L R E R F P S H R F I A E K C V L T H S P T W I I D P I

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence D G T C N F V H R F P T V A V S I G F A V R Q E L E F G V I Y H C T E E R L Y T G R R G R G A F C N G Q R L R V S G E T D L S K A L V L T E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S
T T T T T T T T T T T
G G G

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence I G P K R D P A T L K L F L S N M E R L L H A K A H G V R V I G S S T L A L C H L A S G A A D A Y Y Q F G L H C W D L A A A T V I I R E A G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
T T
S
S
T S
S S
T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . .

Sequence G I V I D T S G G P L D L M A C R V V A A S T R E M A M L I A Q A L Q T

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S S B
T T T T S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	P	W	E	E	C	F	Q	A	A	V	Q	L	A	L	R	A	G	Q	I	I	R	K	A	L	T	E	L	V	T	E	T	D	H	L	V	E	D	L	I	I	S	E	L	R	E	R	F	P	S	H	R	F	I	A	E	K	C	V	L	T	H	S	P	T	W	I	I	D	P	I
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																								S																								T	T												S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	D	G	T	C	N	F	V	H	R	F	P	T	V	A	V	S	I	G	F	A	V	R	Q	E	L	E	F	G	V	I	Y	H	C	T	E	E	R	L	Y	T	G	R	R	G	R	G	A	F	C	N	G	Q	R	L	R	V	S	G	E	T	D	L	S	K	A	L	V	L	T	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T		S											T	T										T	T	T	T							T	T	T					T	T											G	G	G
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	I	G	P	K	R	D	P	A	T	L	K	L	F	L	S	N	M	E	R	L	L	H	A	K	A	H	G	V	R	V	I	G	S	S	T	L	A	L	C	H	L	A	S	G	A	A	D	A	Y	Y	Q	F	G	L	H	C	W	D	L	A	A	A	T	V	I	I	R	E	A	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S																				T	T		S						S												T	S		S						S																T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.
Sequence	G	I	V	I	D	T	S	G	G	P	L	D	L	M	A	C	R	V	V	A	A	S	T	R	E	M	A	M	L	I	A	Q	A	L	Q	T
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S	S	B			T	T	T	T						S	S