PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3epzA_

Fold library id	PDB Header	Molecule	Title
c3epzA_	PDB header: transferase	Chain: A: PDB Molecule: dna (cytosine-5)-methyltransferase 1;	PDBTitle: structure of the replication foci-targeting sequence of2 human dna cytosine methyltransferase dnmt1

Links to external resources
Added to library: Tue Mar 16 12:14:16 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence G P K C I Q C G Q Y L D D P D L K Y G Q H P P D A V D E P Q X L T N E K L S I F D A L P Q H K L T C F S V Y C K H G H L C P I D T G L I E K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
B
T T T
B T T
T T
B
T T
B
T T
B B
S S S S T T T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence N I E L F F S G S A K P I P G G V N G K N L G P I N E W W I T G G E K A L I G F S T S F A E Y I L X D P S P E Y A P I F G L X Q E K I Y I S

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
S
B
S S
B
T T T T T

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence K I V V E F L Q S N S D S T Y E D L I N K I E T T V P P S G L N L N R F T E D S L L R H A Q F V V E Q V E S Y D E A G D Q P I F L T P C X R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
B
G G G
T T
G G G S

. . . . . . . . . 220 . . . . . . .

Sequence D L I K L A G V T L G Q R R A Q A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	G	P	K	C	I	Q	C	G	Q	Y	L	D	D	P	D	L	K	Y	G	Q	H	P	P	D	A	V	D	E	P	Q	X	L	T	N	E	K	L	S	I	F	D	A	L	P	Q	H	K	L	T	C	F	S	V	Y	C	K	H	G	H	L	C	P	I	D	T	G	L	I	E	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			B		T	T	T			B	T	T		T	T			B					T	T		B																														T	T		B	B			S	S	S	S	T	T	T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	N	I	E	L	F	F	S	G	S	A	K	P	I	P	G	G	V	N	G	K	N	L	G	P	I	N	E	W	W	I	T	G	G	E	K	A	L	I	G	F	S	T	S	F	A	E	Y	I	L	X	D	P	S	P	E	Y	A	P	I	F	G	L	X	Q	E	K	I	Y	I	S
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																									S									B								S	S								B		T	T	T					T	T
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	K	I	V	V	E	F	L	Q	S	N	S	D	S	T	Y	E	D	L	I	N	K	I	E	T	T	V	P	P	S	G	L	N	L	N	R	F	T	E	D	S	L	L	R	H	A	Q	F	V	V	E	Q	V	E	S	Y	D	E	A	G	D	Q	P	I	F	L	T	P	C	X	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)											T	T														B			G	G	G												T	T																			G	G	G	S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
Sequence	D	L	I	K	L	A	G	V	T	L	G	Q	R	R	A	Q	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S