Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP27830
DateThu Jan 5 11:44:08 GMT 2012
Unique Job ID98f8500e1f09fb73

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1bxka_
Top template information
Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
Confidence and coverage
Confidence:100.0% Coverage: 96%
341 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDI
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  CDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALT
Secondary structure 
SS confidence 
Disorder 
???
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  EDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPYSASKASSDHLVRAWLRTYGL
Secondary structure 
SS confidence 
Disorder  ??
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  PTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYGNGQQIRDWLYVEDHARALYCVA
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  TTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPHGVAHYRDLITFVADRPGHDLR
Secondary structure 
SS confidence 
Disorder 
?????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.....
Sequence  YAIDASKIARELGWLPQETFESGMRKTVQWYLANESWWKQVQDGSYQGERLGLKG
Secondary structure 
SS confidence 
Disorder 
??????????????????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1bxk chain A

3D model

Region: 1 - 350
Aligned: 341
Modelled: 350
Confidence: 100.0%
Identity: 97%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z45 chain A

3D model

Region: 2 - 339
Aligned: 308
Modelled: 317
Confidence: 100.0%
Identity: 27%
PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose

Phyre2

PDB 1kew chain A

3D model

Region: 1 - 347
Aligned: 342
Modelled: 343
Confidence: 100.0%
Identity: 75%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1z7e chain C

3D model

Region: 1 - 334
Aligned: 322
Modelled: 334
Confidence: 100.0%
Identity: 19%
PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna

Phyre2

PDB 1oc2 chain A

3D model

Region: 1 - 347
Aligned: 334
Modelled: 336
Confidence: 100.0%
Identity: 42%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1r6d chain A

3D model

Region: 1 - 342
Aligned: 317
Modelled: 330
Confidence: 100.0%
Identity: 46%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1i24 chain A

3D model

Region: 2 - 354
Aligned: 345
Modelled: 353
Confidence: 100.0%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2hun chain B

3D model

Region: 1 - 341
Aligned: 317
Modelled: 319
Confidence: 100.0%
Identity: 47%
PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3

Phyre2

PDB 1n7g chain B

3D model

Region: 2 - 346
Aligned: 329
Modelled: 345
Confidence: 100.0%
Identity: 24%
PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.

Phyre2

PDB 1n7h chain A

3D model

Region: 2 - 346
Aligned: 326
Modelled: 345
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2pk3 chain B

3D model

Region: 1 - 333
Aligned: 303
Modelled: 322
Confidence: 100.0%
Identity: 25%
PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase

Phyre2

PDB 1z45 chain A domain 2

3D model

Region: 2 - 339
Aligned: 312
Modelled: 317
Confidence: 100.0%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1ek6 chain A

3D model

Region: 1 - 338
Aligned: 317
Modelled: 326
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 2z1m chain C

3D model

Region: 2 - 334
Aligned: 314
Modelled: 323
Confidence: 100.0%
Identity: 20%
PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5

Phyre2

PDB 3enk chain B

3D model

Region: 2 - 338
Aligned: 315
Modelled: 325
Confidence: 100.0%
Identity: 22%
PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei

Phyre2

PDB 1t2a chain A

3D model

Region: 2 - 336
Aligned: 322
Modelled: 335
Confidence: 100.0%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1udc chain A

3D model

Region: 1 - 340
Aligned: 318
Modelled: 328
Confidence: 100.0%
Identity: 24%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1t2a chain C

3D model

Region: 2 - 336
Aligned: 322
Modelled: 335
Confidence: 100.0%
Identity: 19%
PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase

Phyre2

PDB 1db3 chain A

3D model

Region: 2 - 336
Aligned: 309
Modelled: 318
Confidence: 100.0%
Identity: 22%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2

PDB 1wvg chain A domain 1

3D model

Region: 2 - 350
Aligned: 332
Modelled: 334
Confidence: 100.0%
Identity: 19%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Tyrosine-dependent oxidoreductases

Phyre2
1
d1bxka_
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c1z45A_
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d1kewa_
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c1z7eC_
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d1oc2a_
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d1r6da_
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d1i24a_
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c2hunB_
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c1n7gB_
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d1n7ha_
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c2pk3B_
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d1z45a2
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d1ek6a_
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c2z1mC_
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c3enkB_
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d1t2aa_
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d1udca_
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c1t2aC_
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d1db3a_
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d1wvga1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1bxka_
100.0 97 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
2c1z45A_
100.0 27 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
3d1kewa_
100.0 75 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
4c1z7eC_
100.0 19 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
5d1oc2a_
100.0 42 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
6d1r6da_
100.0 46 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
7d1i24a_
100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
8c2hunB_
100.0 47 PDB header:lyase
Chain: B: PDB Molecule:336aa long hypothetical dtdp-glucose 4,6-dehydratase;
PDBTitle: crystal structure of hypothetical protein ph0414 from pyrococcus2 horikoshii ot3
9c1n7gB_
100.0 24 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
10d1n7ha_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
11c2pk3B_
100.0 25 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
12d1z45a2
100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
13d1ek6a_
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
14c2z1mC_
100.0 20 PDB header:lyase
Chain: C: PDB Molecule:gdp-d-mannose dehydratase;
PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5
15c3enkB_
100.0 22 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
16d1t2aa_
100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
17d1udca_
100.0 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
18c1t2aC_
100.0 19 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
19d1db3a_
100.0 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
20d1wvga1
100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
21c2q1uA_
not modelled 100.0 26 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
22d1rpna_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
23d1rkxa_
not modelled 100.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
24d2c5aa1
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
25c2c20D_
not modelled 100.0 27 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
26d2blla1
not modelled 100.0 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
27c2pzlB_
not modelled 100.0 20 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
28c2p5uC_
not modelled 100.0 28 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
29c2b69A_
not modelled 100.0 23 PDB header:lyase
Chain: A: PDB Molecule:udp-glucuronate decarboxylase 1;
PDBTitle: crystal structure of human udp-glucoronic acid decarboxylase
30d2b69a1
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
31c2q1wC_
not modelled 100.0 21 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
32d1orra_
not modelled 100.0 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
33c3slgB_
not modelled 100.0 19 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
34d1sb8a_
not modelled 100.0 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
35c2iodD_
not modelled 100.0 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:dihydroflavonol 4-reductase;
PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site
36d1gy8a_
not modelled 100.0 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
37d1e6ua_
not modelled 100.0 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
38c3lu1C_
not modelled 100.0 25 PDB header:isomerase
Chain: C: PDB Molecule:wbgu;
PDBTitle: crystal structure analysis of wbgu: a udp-galnac 4-epimerase
39c3m2pD_
not modelled 100.0 19 PDB header:isomerase
Chain: D: PDB Molecule:udp-n-acetylglucosamine 4-epimerase;
PDBTitle: the crystal structure of udp-n-acetylglucosamine 4-epimerase2 from bacillus cereus
40c2x4gA_
not modelled 100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
41c2p4hX_
not modelled 100.0 17 PDB header:plant protein
Chain: X: PDB Molecule:vestitone reductase;
PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.)
42c2hrzA_
not modelled 100.0 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: the crystal structure of the nucleoside-diphosphate-sugar epimerase2 from agrobacterium tumefaciens
43c3a1nB_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:ndp-sugar epimerase;
PDBTitle: crystal structure of l-threonine dehydrogenase from2 hyperthermophilic archaeon thermoplasma volcanium
44c3eheB_
not modelled 100.0 24 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase (gale-1);
PDBTitle: crystal structure of udp-glucose 4 epimerase (gale-1) from2 archaeoglobus fulgidus
45c2yy7B_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:l-threonine dehydrogenase;
PDBTitle: crystal structure of thermolabile l-threonine dehydrogenase from2 flavobacterium frigidimaris kuc-1
46c2rh8A_
not modelled 100.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:anthocyanidin reductase;
PDBTitle: structure of apo anthocyanidin reductase from vitis vinifera
47c2v6gA_
not modelled 100.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:progesterone 5-beta-reductase;
PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp
48c3icpA_
not modelled 100.0 24 PDB header:isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of udp-galactose 4-epimerase
49d1n2sa_
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
50d1vl0a_
not modelled 100.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
51c3sc6F_
not modelled 100.0 17 PDB header:oxidoreductase
Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase;
PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp
52d1y1pa1
not modelled 100.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
53c2x86K_
not modelled 100.0 17 PDB header:isomerase
Chain: K: PDB Molecule:adp-l-glycero-d-manno-heptose-6-epimerase;
PDBTitle: agme bound to adp-b-mannose
54c2ydyA_
not modelled 100.0 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:methionine adenosyltransferase 2 subunit beta;
PDBTitle: crystal structure of human s-adenosylmethionine synthetase2 2, beta subunit in orthorhombic crystal form
55d1eq2a_
not modelled 100.0 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
56c3gpiA_
not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
57c3oh8A_
not modelled 100.0 16 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate sugar epimerase (sula family);
PDBTitle: crystal structure of the nucleoside-diphosphate sugar epimerase from2 corynebacterium glutamicum. northeast structural genomics consortium3 target cgr91
58c2ggsB_
not modelled 100.0 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose
PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii
59c3iusB_
not modelled 100.0 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized conserved protein;
PDBTitle: the structure of a functionally unknown conserved protein2 from silicibacter pomeroyi dss
60c2gn9B_
not modelled 99.9 15 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
61c3e48B_
not modelled 99.9 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
62d1xgka_
not modelled 99.9 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
63c2qx7A_
not modelled 99.9 15 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
64c2zklA_
not modelled 99.9 19 PDB header:isomerase
Chain: A: PDB Molecule:capsular polysaccharide synthesis enzyme cap5f;
PDBTitle: crystal structure of capsular polysaccharide assembling protein capf2 from staphylococcus aureus
65c3i5mA_
not modelled 99.9 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
66c3c1oA_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
67d1qyda_
not modelled 99.9 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
68c2zcuA_
not modelled 99.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
69c2vrcD_
not modelled 99.9 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
70d1qyca_
not modelled 99.9 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
71c2exxB_
not modelled 99.9 12 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
72c2gasA_
not modelled 99.9 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:isoflavone reductase;
PDBTitle: crystal structure of isoflavone reductase
73c3nzoB_
not modelled 99.8 17 PDB header:lyase
Chain: B: PDB Molecule:udp-n-acetylglucosamine 4,6-dehydratase;
PDBTitle: udp-n-acetylglucosamine 4,6-dehydratase from vibrio fischeri.
74c3ay3C_
not modelled 99.8 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens
75c3rfxB_
not modelled 99.8 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:uronate dehydrogenase;
PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad
76d2q46a1
not modelled 99.8 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
77d1hdoa_
not modelled 99.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
78c3dhnA_
not modelled 99.7 18 PDB header:isomerase, lyase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310.
79c3e8xA_
not modelled 99.7 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative nad-dependent epimerase/dehydratase;
PDBTitle: putative nad-dependent epimerase/dehydratase from bacillus halodurans.
80c3dqpA_
not modelled 99.7 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
81c3h2sA_
not modelled 99.6 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative nadh-flavin reductase;
PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19.
82c3qvoA_
not modelled 99.6 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nmra family protein;
PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri.
83d2bkaa1
not modelled 99.5 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84d2a35a1
not modelled 99.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
85c3ew7A_
not modelled 99.4 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:lmo0794 protein;
PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162.
86c2jahB_
not modelled 99.3 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:clavulanic acid dehydrogenase;
PDBTitle: biochemical and structural analysis of the clavulanic acid2 dehydeogenase (cad) from streptomyces clavuligerus
87c3l77A_
not modelled 99.3 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:short-chain alcohol dehydrogenase;
PDBTitle: x-ray structure alcohol dehydrogenase from archaeon thermococcus2 sibiricus complexed with 5-hydroxy-nadp
88d2gdza1
not modelled 99.2 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
89d2fmua1
not modelled 99.2 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
90c2qioA_
not modelled 99.2 11 PDB header:unknown function
Chain: A: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: x-ray structure of enoyl-acyl carrier protein reductase from bacillus2 anthracis with triclosan
91c3i4fD_
not modelled 99.2 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-oxoacyl-[acyl-carrier protein] reductase;
PDBTitle: structure of putative 3-oxoacyl-reductase from bacillus thuringiensis
92c2p68A_
not modelled 99.2 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of aq_1716 from aquifex aeolicus vf5
93c3v8bC_
not modelled 99.2 14 PDB header:oxidoreductase
Chain: C: PDB Molecule:putative dehydrogenase, possibly 3-oxoacyl-[acyl-carrier
PDBTitle: crystal structure of a 3-ketoacyl-acp reductase from sinorhizobium2 meliloti 1021
94c3oidA_
not modelled 99.1 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:enoyl-[acyl-carrier-protein] reductase [nadph];
PDBTitle: crystal structure of enoyl-acp reductases iii (fabl) from b. subtilis2 (complex with nadp and tcl)
95c3m1aF_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative dehydrogenase;
PDBTitle: the crystal structure of a short-chain dehydrogenase from2 streptomyces avermitilis to 2a
96c2cfcB_
not modelled 99.1 11 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase;
PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases
97c3p19A_
not modelled 99.1 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative blue fluorescent protein;
PDBTitle: improved nadph-dependent blue fluorescent protein
98c3toxG_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: G: PDB Molecule:short chain dehydrogenase;
PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021
99d1jtva_
not modelled 99.1 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
100d1sbya1
not modelled 99.1 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
101c3iccA_
not modelled 99.1 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase;
PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution
102c3lylB_
not modelled 99.1 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: structure of 3-oxoacyl-acylcarrier protein reductase, fabg2 from francisella tularensis
103d1qsga_
not modelled 99.1 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
104c2dteB_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glucose 1-dehydrogenase related protein;
PDBTitle: structure of thermoplasma acidophilum aldohexose dehydrogenase (aldt)2 in complex with nadh
105c3un1D_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: D: PDB Molecule:probable oxidoreductase;
PDBTitle: crystal structure of an oxidoreductase from sinorhizobium meliloti2 1021
106c3ijrF_
not modelled 99.1 15 PDB header:oxidoreductase
Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family;
PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+
107c3grkE_
not modelled 99.1 14 PDB header:oxidoreductase
Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh);
PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis
108c3rihB_
not modelled 99.1 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:short chain dehydrogenase or reductase;
PDBTitle: crystal structure of a putative short chain dehydrogenase or reductase2 from mycobacterium abscessus
109c3pk0B_
not modelled 99.0 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: crystal structure of short-chain dehydrogenase/reductase sdr from2 mycobacterium smegmatis
110d1uaya_
not modelled 99.0 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
111c3osuA_
not modelled 99.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of the 3-oxoacyl-acyl carrier protein reductase,2 fabg, from staphylococcus aureus
112c3ppiA_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase type-2;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase type-2 from2 mycobacterium avium
113c3r6dA_
not modelled 99.0 15 PDB header:lyase, isomerase
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine
114c2uvdE_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: E: PDB Molecule:3-oxoacyl-(acyl-carrier-protein) reductase;
PDBTitle: the crystal structure of a 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis (ba3989)
115c3k31B_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:enoyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of eonyl-(acyl-carrier-protein) reductase from2 anaplasma phagocytophilum in complex with nad at 1.9a resolution
116c3ezlA_
not modelled 99.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:acetoacetyl-coa reductase;
PDBTitle: crystal structure of acetyacetyl-coa reductase from2 burkholderia pseudomallei 1710b
117c3v2gA_
not modelled 99.0 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-oxoacyl-[acyl-carrier-protein] reductase;
PDBTitle: crystal structure of a dehydrogenase/reductase from sinorhizobium2 meliloti 1021
118c3ioyB_
not modelled 99.0 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:short-chain dehydrogenase/reductase sdr;
PDBTitle: structure of putative short-chain dehydrogenase (saro_0793)2 from novosphingobium aromaticivorans
119d2ae2a_
not modelled 99.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c3sx2F_
not modelled 99.0 13 PDB header:oxidoreductase
Chain: F: PDB Molecule:putative 3-ketoacyl-(acyl-carrier-protein) reductase;
PDBTitle: crystal structure of a putative 3-ketoacyl-(acyl-carrier-protein)2 reductase from mycobacterium paratuberculosis in complex with nad

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0