Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	R	H	N	V	P	V	R	R	D	L	D	Q	I	A	A	D	N	G	F	D	F	H	I	I	D	N	E	I	Y	W	D	E	S	R	A	Y	R	F	T	L	R	Q	I	E	E	Q	I	E	K	P	T	A	E	L	H	Q	M	C
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	E	V	V	D	R	A	V	K	D	E	E	I	L	T	Q	L	A	I	P	P	L	Y	W	D	V	I	A	E	S	W	R	A	R	D	P	S	L	Y	G	R	M	D	F	A	W	C	G	N	A	P	V	K	L	L	E	Y	N	A	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		T	P	T	S	L	Y	E	S	A	Y	F	Q	W	L	W	L	E	D	A	R	R	S	G	I	I	P	R	D	A	D	Q	Y	N	A	I	Q	E	R	L	I	S	R	F	S	E	L	Y	S	R	E	P	F	Y	F	C	C	C	Q	D	T
Secondary structure
SS confidence
Disorder																						?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	E	D	R	S	T	V	L	Y	L	Q	D	C	A	Q	Q	A	G	Q	E	S	R	F	I	Y	I	E	D	L	G	L	G	V	G	G	V	L	T	D	L	D	D	N	V	I	Q	R	A	F	K	L	Y	P	L	E	W	M	M	R	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	N	G	P	L	L	R	K	R	R	E	Q	W	V	E	P	L	W	K	S	I	L	S	N	K	G	L	M	P	L	L	W	R	F	F	P	G	H	P	N	L	L	A	S	W	F	D	G	E	K	P	Q	I	A	A	G	E	S	Y	V
Secondary structure
SS confidence
Disorder																																																			?		?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		R	K	P	I	Y	S	R	E	G	G	N	V	T	I	F	D	G	K	N	N	V	V	D	H	A	D	G	D	Y	A	D	E	P	M	I	Y	Q	A	F	Q	P	L	P	R	F	G	D	S	Y	T	L	I	G	S	W	I	V	D	D	E
Secondary structure
SS confidence
Disorder																										?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.
Sequence		A	C	G	M	G	I	R	E	D	N	T	L	I	T	K	D	T	S	R	F	V	P	H	Y	I	A	G
Secondary structure
SS confidence
Disorder												?															?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ioa chain A Region: 33 - 385 Aligned: 341 Modelled: 353 Confidence: 100.0% Identity: 27% PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor Phyre2 PDB 2vpm chain B Region: 10 - 386 Aligned: 331 Modelled: 348 Confidence: 100.0% Identity: 27% PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase Phyre2 PDB 2io8 chain A domain 3 Region: 10 - 384 Aligned: 273 Modelled: 274 Confidence: 100.0% Identity: 29% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Glutathionylspermidine synthase ATP-binding domain-like Phyre2 PDB 3n6x chain A Region: 12 - 378 Aligned: 350 Modelled: 367 Confidence: 100.0% Identity: 11% PDB header:ligase Chain: A: PDB Molecule:putative glutathionylspermidine synthase; PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution Phyre2 PDB 2io8 chain A domain 1 Region: 169 - 277 Aligned: 108 Modelled: 109 Confidence: 99.9% Identity: 19% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: Glutathionylspermidine synthase substrate-binding domain-like Phyre2 PDB 2hgs chain A Region: 43 - 385 Aligned: 332 Modelled: 340 Confidence: 99.6% Identity: 13% PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase Phyre2 PDB 3kal chain B Region: 42 - 367 Aligned: 311 Modelled: 326 Confidence: 99.5% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound Phyre2 PDB 1m0t chain B Region: 35 - 367 Aligned: 318 Modelled: 333 Confidence: 99.4% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:glutathione synthetase; PDBTitle: yeast glutathione synthase Phyre2 PDB 2wyo chain C Region: 42 - 385 Aligned: 319 Modelled: 321 Confidence: 99.3% Identity: 14% PDB header:ligase Chain: C: PDB Molecule:glutathione synthetase; PDBTitle: trypanosoma brucei glutathione synthetase Phyre2 PDB 1gsh chain A Region: 171 - 369 Aligned: 192 Modelled: 199 Confidence: 99.0% Identity: 16% PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 Phyre2 PDB 2hgs chain A domain 4 Region: 43 - 385 Aligned: 239 Modelled: 245 Confidence: 98.6% Identity: 15% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Eukaryotic glutathione synthetase ATP-binding domain Phyre2 PDB 2p0a chain A Region: 170 - 378 Aligned: 202 Modelled: 209 Confidence: 98.2% Identity: 12% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp Phyre2 PDB 1uc8 chain B Region: 188 - 374 Aligned: 169 Modelled: 187 Confidence: 98.0% Identity: 15% PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 Phyre2 PDB 1i7n chain A Region: 243 - 378 Aligned: 128 Modelled: 136 Confidence: 97.9% Identity: 10% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain Phyre2 PDB 1pk8 chain D Region: 242 - 384 Aligned: 135 Modelled: 143 Confidence: 97.9% Identity: 13% PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp Phyre2 PDB 2qb5 chain B Region: 166 - 370 Aligned: 193 Modelled: 205 Confidence: 97.8% Identity: 10% PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ Phyre2 PDB 1pk8 chain A domain 2 Region: 255 - 386 Aligned: 127 Modelled: 132 Confidence: 97.8% Identity: 12% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Synapsin C-terminal domain Phyre2 PDB 1m0w chain A domain 2 Region: 42 - 367 Aligned: 235 Modelled: 251 Confidence: 97.6% Identity: 17% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Eukaryotic glutathione synthetase ATP-binding domain Phyre2 PDB 3ln7 chain A Region: 296 - 386 Aligned: 83 Modelled: 91 Confidence: 97.4% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida Phyre2 PDB 1kjj chain A Region: 187 - 341 Aligned: 155 Modelled: 155 Confidence: 97.3% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s Phyre2 1 c2ioaA_ 2 c2vpmB_ 3 d2io8a3 4 c3n6xA_ 5 d2io8a1 6 c2hgsA_ 7 c3kalB_ 8 c1m0tB_ 9 c2wyoC_ 10 c1gshA_ 11 d2hgsa4 12 c2p0aA_ 13 c1uc8B_ 14 c1i7nA_ 15 c1pk8D_ 16 c2qb5B_ 17 d1pk8a2 18 d1m0wa2 19 c3ln7A_ 20 c1kjjA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ioaA_ 100.0 27 PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor 2 c2vpmB_ 100.0 27 PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase 3 d2io8a3 100.0 29 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Glutathionylspermidine synthase ATP-binding domain-like 4 c3n6xA_ 100.0 11 PDB header:ligase Chain: A: PDB Molecule:putative glutathionylspermidine synthase; PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution 5 d2io8a1 99.9 19 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Glutathionylspermidine synthase substrate-binding domain-like 6 c2hgsA_ 99.6 13 PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase 7 c3kalB_ 99.5 14 PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound 8 c1m0tB_ 99.4 16 PDB header:ligase Chain: B: PDB Molecule:glutathione synthetase; PDBTitle: yeast glutathione synthase 9 c2wyoC_ 99.3 14 PDB header:ligase Chain: C: PDB Molecule:glutathione synthetase; PDBTitle: trypanosoma brucei glutathione synthetase 10 c1gshA_ 99.0 16 PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 11 d2hgsa4 98.6 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Eukaryotic glutathione synthetase ATP-binding domain 12 c2p0aA_ 98.2 12 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp 13 c1uc8B_ 98.0 15 PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 14 c1i7nA_ 97.9 10 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain 15 c1pk8D_ 97.9 13 PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp 16 c2qb5B_ 97.8 10 PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ 17 d1pk8a2 97.8 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 18 d1m0wa2 97.6 17 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Eukaryotic glutathione synthetase ATP-binding domain 19 c3ln7A_ 97.4 18 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida 20 c1kjjA_ 97.3 13 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 21 d1gsaa2 not modelled 97.2 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 22 c3t9aA_ not modelled 97.1 20 PDB header:transferase Chain: A: PDB Molecule:inositol pyrophosphate kinase; PDBTitle: crystal structure of the catalytic domain of human diphosphoinositol2 pentakisphosphate kinase 2 (ppip5k2) in complex with amppnp at ph 7.0 23 c2dlnA_ not modelled 97.0 11 PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution 24 d1i7na2 not modelled 96.9 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 25 c3ln6A_ not modelled 96.9 13 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae 26 c2xd4A_ not modelled 96.2 11 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase 27 c2yyaB_ not modelled 96.2 11 PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus 28 c3bg5C_ not modelled 95.8 13 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 29 c3lwbA_ not modelled 95.8 11 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of apo d-alanine:d-alanine ligase (ddl) from2 mycobacterium tuberculosis 30 c3orqA_ not modelled 95.6 8 PDB header:ligase,biosynthetic protein Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp 31 c2ip4A_ not modelled 95.5 11 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8 32 d1uc8a2 not modelled 95.5 18 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Lysine biosynthesis enzyme LysX ATP-binding domain 33 c1vkzA_ not modelled 95.3 18 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution 34 c3lp8A_ not modelled 95.1 15 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase; PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis 35 c3df7A_ not modelled 94.8 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative atp-grasp superfamily protein; PDBTitle: crystal structure of a putative atp-grasp superfamily2 protein from archaeoglobus fulgidus 36 c2hjwA_ not modelled 94.2 12 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 37 c3ouzA_ not modelled 93.6 14 PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni 38 c3tinA_ not modelled 93.5 23 PDB header:ligase Chain: A: PDB Molecule:ttl protein; PDBTitle: tubulin tyrosine ligase 39 c2cqyA_ not modelled 93.4 16 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: solution structure of b domain from human propionyl-coa2 carboxylase alpha subunit 40 c3gidB_ not modelled 93.4 12 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a 41 c1ulzA_ not modelled 93.3 15 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 42 c1z2pX_ not modelled 93.2 10 PDB header:transferase Chain: X: PDB Molecule:inositol 1,3,4-trisphosphate 5/6-kinase; PDBTitle: inositol 1,3,4-trisphosphate 5/6-kinase in complex with mg2+/amp-2 pcp/ins(1,3,4)p3 43 c2vpqA_ not modelled 93.1 13 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp 44 d1gsaa1 not modelled 92.6 16 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Prokaryotic glutathione synthetase, N-terminal domain 45 c3uvzB_ not modelled 92.4 10 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria 46 c3g8cB_ not modelled 92.3 10 PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion 47 c3tqtB_ not modelled 91.5 22 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: structure of the d-alanine-d-alanine ligase from coxiella burnetii 48 d1a9xa5 not modelled 91.3 8 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 49 c1e4eB_ not modelled 90.3 8 PDB header:ligase Chain: B: PDB Molecule:vancomycin/teicoplanin a-type resistance protein vana; PDBTitle: d-alanyl-d-lacate ligase 50 d1e4ea2 not modelled 89.8 19 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 51 c2dzdB_ not modelled 89.7 12 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 52 c2i80B_ not modelled 89.7 29 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies 53 d1w96a3 not modelled 89.3 9 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 54 c3se7A_ not modelled 89.0 31 PDB header:ligase Chain: A: PDB Molecule:vana; PDBTitle: ancient vana 55 c2pvpB_ not modelled 88.7 11 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: crystal structure of d-alanine-d-alanine ligase from helicobacter2 pylori 56 c1ehiB_ not modelled 88.6 38 PDB header:ligase Chain: B: PDB Molecule:d-alanine:d-lactate ligase; PDBTitle: d-alanine:d-lactate ligase (lmddl2) of vancomycin-resistant2 leuconostoc mesenteroides 57 d1gsoa3 not modelled 88.2 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 58 c1w96B_ not modelled 88.0 9 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 59 c3i12A_ not modelled 87.8 24 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2 60 c3etjB_ not modelled 87.5 10 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi 61 d1ehia2 not modelled 87.3 38 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 62 c3e5nA_ not modelled 86.9 24 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: crystal strucutre of d-alanine-d-alanine ligase from2 xanthomonas oryzae pv. oryzae kacc10331 63 d1iowa2 not modelled 85.7 33 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 64 c2ys6A_ not modelled 85.3 9 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase; PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus 65 d2r85a2 not modelled 85.0 8 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 66 c3q2oB_ not modelled 84.9 11 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase 67 d2r7ka2 not modelled 83.9 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 68 c3k3pA_ not modelled 83.9 33 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of the apo form of d-alanine:d-alanine ligase (ddl)2 from streptococcus mutans 69 c2zdqA_ not modelled 82.2 7 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine:d-alanine ligase with atp2 and d-alanine:d-alanine from thermus thermophius hb8 70 c3k5iB_ not modelled 82.0 9 PDB header:lyase Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide 71 d1vkza3 not modelled 76.5 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 72 d1kjqa3 not modelled 75.0 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 73 c1m6vE_ not modelled 71.9 9 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 74 c1gsoA_ not modelled 69.5 14 PDB header:ligase Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase); PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli. 75 c3u9sE_ not modelled 68.6 19 PDB header:ligase Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit; PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex 76 c2z04A_ not modelled 68.0 12 PDB header:lyase Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure of phosphoribosylaminoimidazole2 carboxylase atpase subunit from aquifex aeolicus 77 d3etja3 not modelled 67.3 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 78 c3r23B_ not modelled 64.5 25 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine--d-alanine ligase from bacillus2 anthracis 79 c3n6rK_ not modelled 63.2 29 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 80 c2dwcB_ not modelled 59.5 11 PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp 81 d1ulza3 not modelled 54.9 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 82 c2qk4A_ not modelled 54.1 12 PDB header:ligase Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3; PDBTitle: human glycinamide ribonucleotide synthetase 83 c2gpwC_ not modelled 52.8 20 PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. 84 c2r85B_ not modelled 52.7 8 PDB header:unknown function Chain: B: PDB Molecule:purp protein pf1517; PDBTitle: crystal structure of purp from pyrococcus furiosus complexed with amp 85 c3k1tA_ not modelled 42.6 15 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase gsha; PDBTitle: crystal structure of putative gamma-glutamylcysteine synthetase2 (yp_546622.1) from methylobacillus flagellatus kt at 1.90 a3 resolution 86 c2pn1A_ not modelled 42.1 9 PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution 87 d2hgsa1 not modelled 38.4 12 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Eukaryotic glutathione synthetase, substrate-binding domain 88 d1a9xa6 not modelled 37.4 21 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 89 d2j9ga3 not modelled 34.2 9 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 90 d2oo3a1 not modelled 23.7 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:LPG1296-like 91 d1rz3a_ not modelled 18.5 9 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:Phosphoribulokinase/pantothenate kinase 92 c1w5kB_ not modelled 17.7 38 PDB header:four helix bundle Chain: B: PDB Molecule:general control protein gcn4; PDBTitle: an anti-parallel four helix bundle 93 c1w5kC_ not modelled 17.7 38 PDB header:four helix bundle Chain: C: PDB Molecule:general control protein gcn4; PDBTitle: an anti-parallel four helix bundle 94 c1w5kA_ not modelled 17.7 38 PDB header:four helix bundle Chain: A: PDB Molecule:general control protein gcn4; PDBTitle: an anti-parallel four helix bundle 95 c1w5kD_ not modelled 17.7 38 PDB header:four helix bundle Chain: D: PDB Molecule:general control protein gcn4; PDBTitle: an anti-parallel four helix bundle 96 c1vraB_ not modelled 16.0 14 PDB header:transferase Chain: B: PDB Molecule:arginine biosynthesis bifunctional protein argj; PDBTitle: crystal structure of arginine biosynthesis bifunctional protein argj2 (10175521) from bacillus halodurans at 2.00 a resolution 97 c2vzkD_ not modelled 15.6 11 PDB header:transferase Chain: D: PDB Molecule:glutamate n-acetyltransferase 2 beta chain; PDBTitle: structure of the acyl-enzyme complex of an n-terminal2 nucleophile (ntn) hydrolase, oat2 98 c3e90C_ not modelled 14.7 20 PDB header:hydrolase Chain: C: PDB Molecule:ns2b cofactor; PDBTitle: west nile vi rus ns2b-ns3protease in complexed with2 inhibitor naph-kkr-h 99 c2ijoA_ not modelled 14.5 20 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:polyprotein; PDBTitle: crystal structure of the west nile virus ns2b-ns3 protease2 complexed with bovine pancreatic trypsin inhibitor

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0