Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	L	Q	H	W	Q	A	Q	F	E	N	W	L	K	N	H	H	Q	H	Q	D	A	A	H	D	V	C	H	F	R	R	V	W	A	T	A	Q	K	L	A	A	D	D	D	V	D	M	L	V	I	L	T	A	C	Y	F	H	D	I
Secondary structure
SS confidence
Disorder		?	?																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	S	L	A	K	N	H	P	Q	R	Q	R	S	S	I	L	A	A	E	E	T	R	R	L	L	R	E	E	F	E	Q	F	P	A	E	K	I	E	A	V	C	H	A	I	A	A	H	S	F	S	A	Q	I	A	P	L	T	T	E	A
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?	?	?	?																																			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	I	V	Q	D	A	D	R	L	E	A	L	G	A	I	G	L	A	R	V	F	A	V	S	G	A	L	G	V	A	L	F	D	G	E	D	P	F	A	Q	H	R	P	L	D	D	K	R	Y	A	L	D	H	F	Q	T	K	L	L	K
Secondary structure
SS confidence
Disorder																																?			?			?	?			?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.
Sequence		L	P	Q	T	M	Q	T	A	R	G	K	Q	L	A	Q	H	N	A	H	F	L	V	E	F	M	A	K	L	S	A	E	L	A	G	E	N	E	G	V	D	H	K	V	I	D	A	F	S	S	A	G
Secondary structure
SS confidence
Disorder																																		?	?	?		?	?	?									?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3gw7 chain A Region: 4 - 231 Aligned: 209 Modelled: 228 Confidence: 100.0% Identity: 96% PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein yedj; PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63 Phyre2 PDB 2pjq chain A domain 1 Region: 1 - 215 Aligned: 198 Modelled: 200 Confidence: 100.0% Identity: 31% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2qgs chain A domain 1 Region: 1 - 215 Aligned: 203 Modelled: 214 Confidence: 100.0% Identity: 29% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3djb chain A domain 1 Region: 3 - 215 Aligned: 187 Modelled: 192 Confidence: 100.0% Identity: 34% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3dto chain A domain 1 Region: 2 - 214 Aligned: 187 Modelled: 201 Confidence: 100.0% Identity: 35% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 3b57 chain A domain 1 Region: 1 - 213 Aligned: 177 Modelled: 190 Confidence: 100.0% Identity: 34% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2pq7 chain A domain 1 Region: 7 - 213 Aligned: 161 Modelled: 169 Confidence: 100.0% Identity: 32% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2o08 chain B Region: 11 - 131 Aligned: 115 Modelled: 121 Confidence: 99.4% Identity: 23% PDB header:hydrolase Chain: B: PDB Molecule:bh1327 protein; PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution Phyre2 PDB 3ccg chain A Region: 7 - 130 Aligned: 114 Modelled: 124 Confidence: 99.4% Identity: 22% PDB header:hydrolase Chain: A: PDB Molecule:hd superfamily hydrolase; PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution Phyre2 PDB 2ogi chain A Region: 1 - 131 Aligned: 117 Modelled: 131 Confidence: 99.4% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein sag1661; PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution Phyre2 PDB 3mzo chain A Region: 28 - 211 Aligned: 149 Modelled: 161 Confidence: 98.8% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:lin2634 protein; PDBTitle: crystal structure of a hd-domain phosphohydrolase (lin2634) from2 listeria innocua at 1.98 a resolution Phyre2 PDB 2dqb chain B Region: 27 - 133 Aligned: 102 Modelled: 102 Confidence: 98.7% Identity: 16% PDB header:hydrolase, dna binding protein Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative; PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase Phyre2 PDB 2cqz chain A Region: 28 - 151 Aligned: 107 Modelled: 107 Confidence: 98.7% Identity: 18% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:177aa long hypothetical protein; PDBTitle: crystal structure of ph0347 protein from pyrococcus horikoshii ot3 Phyre2 PDB 2paq chain A domain 1 Region: 28 - 132 Aligned: 96 Modelled: 105 Confidence: 98.6% Identity: 22% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 1ynb chain A domain 1 Region: 28 - 196 Aligned: 119 Modelled: 124 Confidence: 98.6% Identity: 21% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2o6i chain A Region: 27 - 210 Aligned: 168 Modelled: 184 Confidence: 98.5% Identity: 16% PDB header:hydrolase Chain: A: PDB Molecule:hd domain protein; PDBTitle: structure of an enterococcus faecalis hd domain phosphohydrolase Phyre2 PDB 2o6i chain A domain 1 Region: 27 - 210 Aligned: 168 Modelled: 184 Confidence: 98.5% Identity: 16% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 PDB 2q14 chain A Region: 27 - 211 Aligned: 164 Modelled: 176 Confidence: 98.5% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:phosphohydrolase; PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution Phyre2 PDB 3m1t chain A Region: 27 - 185 Aligned: 140 Modelled: 135 Confidence: 98.5% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:putative phosphohydrolase; PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution Phyre2 PDB 2hek chain A domain 1 Region: 27 - 151 Aligned: 117 Modelled: 120 Confidence: 98.5% Identity: 15% Fold: HD-domain/PDEase-like Superfamily: HD-domain/PDEase-like Family: HD domain Phyre2 1 c3gw7A_ 2 d2pjqa1 3 d2qgsa1 4 d3djba1 5 d3dtoa1 6 d3b57a1 7 d2pq7a1 8 c2o08B_ 9 c3ccgA_ 10 c2ogiA_ 11 c3mzoA_ 12 c2dqbB_ 13 c2cqzA_ 14 d2paqa1 15 d1ynba1 16 c2o6iA_ 17 d2o6ia1 18 c2q14A_ 19 c3m1tA_ 20 d2heka1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3gw7A_ 100.0 96 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized protein yedj; PDBTitle: crystal structure of a metal-dependent phosphohydrolase2 with conserved hd domain (yedj) from escherichia coli in3 complex with nickel ions. northeast structural genomics4 consortium target er63 2 d2pjqa1 100.0 31 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 3 d2qgsa1 100.0 29 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 4 d3djba1 100.0 34 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 5 d3dtoa1 100.0 35 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 6 d3b57a1 100.0 34 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 7 d2pq7a1 100.0 32 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 8 c2o08B_ 99.4 23 PDB header:hydrolase Chain: B: PDB Molecule:bh1327 protein; PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution 9 c3ccgA_ 99.4 22 PDB header:hydrolase Chain: A: PDB Molecule:hd superfamily hydrolase; PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution 10 c2ogiA_ 99.4 21 PDB header:hydrolase Chain: A: PDB Molecule:hypothetical protein sag1661; PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution 11 c3mzoA_ 98.8 19 PDB header:hydrolase Chain: A: PDB Molecule:lin2634 protein; PDBTitle: crystal structure of a hd-domain phosphohydrolase (lin2634) from2 listeria innocua at 1.98 a resolution 12 c2dqbB_ 98.7 16 PDB header:hydrolase, dna binding protein Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative; PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase 13 c2cqzA_ 98.7 18 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:177aa long hypothetical protein; PDBTitle: crystal structure of ph0347 protein from pyrococcus horikoshii ot3 14 d2paqa1 98.6 22 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 15 d1ynba1 98.6 21 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 16 c2o6iA_ 98.5 16 PDB header:hydrolase Chain: A: PDB Molecule:hd domain protein; PDBTitle: structure of an enterococcus faecalis hd domain phosphohydrolase 17 d2o6ia1 98.5 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 18 c2q14A_ 98.5 18 PDB header:hydrolase Chain: A: PDB Molecule:phosphohydrolase; PDBTitle: crystal structure of phosphohydrolase (bt4208) from bacteroides2 thetaiotaomicron vpi-5482 at 2.20 a resolution 19 c3m1tA_ 98.5 18 PDB header:hydrolase Chain: A: PDB Molecule:putative phosphohydrolase; PDBTitle: crystal structure of putative phosphohydrolase (yp_929327.1) from2 shewanella amazonensis sb2b at 1.62 a resolution 20 d2heka1 98.5 15 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 21 c2pgsA_ not modelled 98.4 19 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyguanosinetriphosphate triphosphohydrolase; PDBTitle: crystal structure of a putative deoxyguanosinetriphosphate2 triphosphohydrolase from pseudomonas syringae pv. phaseolicola 1448a 22 c3kh1B_ not modelled 98.4 19 PDB header:hydrolase Chain: B: PDB Molecule:predicted metal-dependent phosphohydrolase; PDBTitle: crystal structure of predicted metal-dependent2 phosphohydrolase (zp_00055740.2) from magnetospirillum3 magnetotacticum ms-1 at 1.37 a resolution 23 c2floA_ not modelled 98.2 16 PDB header:hydrolase Chain: A: PDB Molecule:exopolyphosphatase; PDBTitle: crystal structure of exopolyphosphatase (ppx) from e. coli o157:h7 24 d1xx7a_ not modelled 98.2 23 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 25 c3u1nC_ not modelled 98.1 18 PDB header:hydrolase Chain: C: PDB Molecule:sam domain and hd domain-containing protein 1; PDBTitle: structure of the catalytic core of human samhd1 26 d1u6za1 not modelled 98.1 17 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:Ppx associated domain 27 c3hc1A_ not modelled 98.0 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized hdod domain protein; PDBTitle: crystal structure of hdod domain protein with unknown function2 (np_953345.1) from geobacter sulfurreducens at 1.90 a resolution 28 c3memA_ not modelled 97.9 21 PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution 29 c3hi0B_ not modelled 97.8 11 PDB header:hydrolase Chain: B: PDB Molecule:putative exopolyphosphatase; PDBTitle: crystal structure of putative exopolyphosphatase (17739545) from2 agrobacterium tumefaciens str. c58 (dupont) at 2.30 a resolution 30 c3i7aA_ not modelled 97.7 17 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent phosphohydrolase; PDBTitle: crystal structure of putative metal-dependent phosphohydrolase2 (yp_926882.1) from shewanella amazonensis sb2b at 2.06 a resolution 31 c3bg2A_ not modelled 97.6 16 PDB header:hydrolase Chain: A: PDB Molecule:dgtp triphosphohydrolase; PDBTitle: crystal structure of deoxyguanosinetriphosphate triphosphohydrolase2 from flavobacterium sp. med217 32 d1vqra_ not modelled 97.5 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:modified HD domain 33 c3skdA_ not modelled 97.3 21 PDB header:hydrolase Chain: A: PDB Molecule:putative uncharacterized protein tthb187; PDBTitle: crystal structure of the thermus thermophilus cas3 hd domain in the2 presence of ni2+ 34 c3m5fA_ not modelled 97.3 14 PDB header:hydrolase Chain: A: PDB Molecule:metal dependent phosphohydrolase; PDBTitle: structure of mj0384, a cas3 protein from methanocaldococcus jannaschii 35 c1vj7B_ not modelled 96.9 19 PDB header:hydrolase, transferase Chain: B: PDB Molecule:bifunctional rela/spot; PDBTitle: crystal structure of the bifunctional catalytic fragment of relseq,2 the rela/spot homolog from streptococcus equisimilis. 36 d2gz4a1 not modelled 96.7 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 37 c3ljvA_ not modelled 96.5 22 PDB header:transcription Chain: A: PDB Molecule:mmoq response regulator; PDBTitle: crystal structure of mmoq response regulator (fragment 29-302) from2 methylococcus capsulatus str. bath, northeast structural genomics3 consortium target mcr175m 38 c3nr1A_ not modelled 96.4 22 PDB header:hydrolase Chain: A: PDB Molecule:hd domain-containing protein 3; PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses 39 c3nqwB_ not modelled 96.1 20 PDB header:hydrolase Chain: B: PDB Molecule:cg11900; PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses 40 d1vj7a1 not modelled 96.1 19 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:HD domain 41 c1xozA_ not modelled 95.5 15 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: catalytic domain of human phosphodiesterase 5a in complex2 with tadalafil 42 d1tbfa_ not modelled 95.5 15 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 43 c2ounA_ not modelled 95.4 15 PDB header:hydrolase Chain: A: PDB Molecule:camp and camp-inhibited cgmp 3',5'-cyclic PDBTitle: crystal structure of pde10a2 in complex with amp 44 d3dy8a1 not modelled 95.4 21 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 45 c2o8hA_ not modelled 95.4 14 PDB header:hydrolase Chain: A: PDB Molecule:phosphodiesterase-10a; PDBTitle: crystal structure of the catalytic domain of rat2 phosphodiesterase 10a 46 d2h44a1 not modelled 95.3 18 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 47 d1y2ka1 not modelled 95.3 23 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 48 c3qi4A_ not modelled 95.3 21 PDB header:hydrolase Chain: A: PDB Molecule:high affinity cgmp-specific 3',5'-cyclic phosphodiesterase PDBTitle: crystal structure of pde9a(q453e) in complex with ibmx 49 c2r8qA_ not modelled 95.3 17 PDB header:hydrolase Chain: A: PDB Molecule:class i phosphodiesterase pdeb1; PDBTitle: structure of lmjpdeb1 in complex with ibmx 50 c1z1lA_ not modelled 95.1 13 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase; PDBTitle: the crystal structure of the phosphodiesterase 2a catalytic2 domain 51 c3ibjB_ not modelled 95.1 11 PDB header:hydrolase Chain: B: PDB Molecule:cgmp-dependent 3',5'-cyclic phosphodiesterase; PDBTitle: x-ray structure of pde2a 52 c3kq5A_ not modelled 94.9 5 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical cytosolic protein; PDBTitle: crystal structure of an uncharacterized protein from coxiella burnetii 53 d1f0ja_ not modelled 94.9 22 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 54 c3ecmA_ not modelled 94.7 17 PDB header:hydrolase Chain: A: PDB Molecule:high affinity camp-specific and ibmx-insensitive PDBTitle: crystal structure of the unliganded pde8a catalytic domain 55 c1xotB_ not modelled 94.6 20 PDB header:hydrolase Chain: B: PDB Molecule:camp-specific 3',5'-cyclic phosphodiesterase 4b; PDBTitle: catalytic domain of human phosphodiesterase 4b in complex with2 vardenafil 56 c3bjcA_ not modelled 94.6 17 PDB header:hydrolase Chain: A: PDB Molecule:cgmp-specific 3',5'-cyclic phosphodiesterase; PDBTitle: crystal structure of the pde5a catalytic domain in complex2 with a novel inhibitor 57 c3g3nA_ not modelled 94.4 20 PDB header:hydrolase Chain: A: PDB Molecule:high affinity camp-specific 3',5'-cyclic PDBTitle: pde7a catalytic domain in complex with 3-(2,6-2 difluorophenyl)-2-(methylthio)quinazolin-4(3h)-one 58 c1zklA_ not modelled 93.9 21 PDB header:hydrolase Chain: A: PDB Molecule:high-affinity camp-specific 3',5'-cyclic PDBTitle: multiple determinants for inhibitor selectivity of cyclic2 nucleotide phosphodiesterases 59 d1taza_ not modelled 93.4 20 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 60 d1so2a_ not modelled 92.6 16 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:PDEase 61 c3aqnA_ not modelled 83.5 6 PDB header:transferase Chain: A: PDB Molecule:poly(a) polymerase; PDBTitle: complex structure of bacterial protein (apo form ii) 62 d3bxda1 not modelled 82.7 14 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 63 c2huoA_ not modelled 82.7 14 PDB header:oxidoreductase Chain: A: PDB Molecule:inositol oxygenase; PDBTitle: crystal structure of mouse myo-inositol oxygenase in complex with2 substrate 64 d2ibna1 not modelled 70.2 13 Fold:HD-domain/PDEase-like Superfamily:HD-domain/PDEase-like Family:MioX-like 65 d1g3wa2 not modelled 64.6 12 Fold:Iron-dependent repressor protein, dimerization domain Superfamily:Iron-dependent repressor protein, dimerization domain Family:Iron-dependent repressor protein, dimerization domain 66 c1g3wA_ not modelled 57.7 12 PDB header:gene regulation Chain: A: PDB Molecule:diphtheria toxin repressor; PDBTitle: cd-cys102ser dtxr 67 c3hruA_ not modelled 51.7 17 PDB header:transcription Chain: A: PDB Molecule:metalloregulator scar; PDBTitle: crystal structure of scar with bound zn2+ 68 d2ev0a2 not modelled 51.4 20 Fold:Iron-dependent repressor protein, dimerization domain Superfamily:Iron-dependent repressor protein, dimerization domain Family:Iron-dependent repressor protein, dimerization domain 69 d1f5ta2 not modelled 44.8 19 Fold:Iron-dependent repressor protein, dimerization domain Superfamily:Iron-dependent repressor protein, dimerization domain Family:Iron-dependent repressor protein, dimerization domain 70 c1fx7C_ not modelled 43.3 17 PDB header:signaling protein Chain: C: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of the iron-dependent regulator (ider)2 from mycobacterium tuberculosis 71 d2isya2 not modelled 43.0 19 Fold:Iron-dependent repressor protein, dimerization domain Superfamily:Iron-dependent repressor protein, dimerization domain Family:Iron-dependent repressor protein, dimerization domain 72 c3dptB_ not modelled 41.4 12 PDB header:signaling protein Chain: B: PDB Molecule:rab family protein; PDBTitle: cor domain of rab family protein (roco) 73 d1jjcb1 not modelled 33.8 52 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Domains B1 and B5 of PheRS-beta, PheT 74 c3pcoD_ not modelled 31.5 32 PDB header:ligase Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 75 c2ev5B_ not modelled 24.4 20 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator mntr; PDBTitle: bacillus subtilis manganese transport regulator (mntr)2 bound to calcium 76 d1s3ja_ not modelled 24.4 17 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators 77 c3nzpA_ not modelled 23.1 8 PDB header:lyase Chain: A: PDB Molecule:arginine decarboxylase; PDBTitle: crystal structure of the biosynthetic arginine decarboxylase spea from2 campylobacter jejuni, northeast structural genomics consortium target3 br53 78 c2akwB_ not modelled 22.9 47 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine 79 c2cxiA_ not modelled 20.5 26 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of an n-terminal fragment of the phenylalanyl-trna2 synthetase beta-subunit from pyrococcus horikoshii 80 c3l4gL_ not modelled 19.0 35 PDB header:ligase Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 81 c3bjaA_ not modelled 17.7 13 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, marr family, putative; PDBTitle: crystal structure of putative marr-like transcription regulator2 (np_978771.1) from bacillus cereus atcc 10987 at 2.38 a resolution 82 c3kp3B_ not modelled 12.9 7 PDB header:transcription regulator/antibiotic Chain: B: PDB Molecule:transcriptional regulator tcar; PDBTitle: staphylococcus epidermidis in complex with ampicillin 83 c3f3xA_ not modelled 12.8 13 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family, putative; PDBTitle: crystal structure of the transcriptional regulator bldr2 from sulfolobus solfataricus 84 c2rhsB_ not modelled 12.3 23 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 85 c2gxgA_ not modelled 12.0 10 PDB header:transcription Chain: A: PDB Molecule:146aa long hypothetical transcriptional regulator; PDBTitle: crystal structure of emrr homolog from hyperthermophilic archaea2 sulfolobus tokodaii strain7 86 d2a61a1 not modelled 11.8 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:MarR-like transcriptional regulators 87 c3nqoB_ not modelled 11.5 20 PDB header:transcription Chain: B: PDB Molecule:marr-family transcriptional regulator; PDBTitle: crystal structure of a marr family transcriptional regulator (cd1569)2 from clostridium difficile 630 at 2.20 a resolution 88 c3e6mD_ not modelled 11.3 20 PDB header:transcription regulator Chain: D: PDB Molecule:marr family transcriptional regulator; PDBTitle: the crystal structure of a marr family transcriptional2 regulator from silicibacter pomeroyi dss. 89 c3nrvC_ not modelled 10.0 23 PDB header:transcription regulator Chain: C: PDB Molecule:putative transcriptional regulator (marr/emrr family); PDBTitle: crystal structure of marr/emrr family transcriptional regulator from2 acinetobacter sp. adp1 90 c2w31A_ not modelled 9.2 21 PDB header:oxygen transport Chain: A: PDB Molecule:globin; PDBTitle: globin domain of geobacter sulfurreducens globin-coupled2 sensor 91 d1ylea1 not modelled 9.1 6 Fold:Acyl-CoA N-acyltransferases (Nat) Superfamily:Acyl-CoA N-acyltransferases (Nat) Family:AstA-like 92 c3jw4C_ not modelled 8.9 13 PDB header:transcription regulator Chain: C: PDB Molecule:transcriptional regulator, marr/emrr family; PDBTitle: the structure of a putative marr family transcriptional regulator from2 clostridium acetobutylicum 93 c2nnnB_ not modelled 8.8 13 PDB header:transcription Chain: B: PDB Molecule:probable transcriptional regulator; PDBTitle: crystal structure of probable transcriptional regulator from2 pseudomonas aeruginosa 94 c2zycA_ not modelled 8.5 18 PDB header:hydrolase Chain: A: PDB Molecule:peptidoglycan hydrolase flgj; PDBTitle: crystal structure of peptidoglycan hydrolase from2 sphingomonas sp. a1 95 c2ek0B_ not modelled 8.4 45 PDB header:metal binding protein Chain: B: PDB Molecule:stage v sporulation protein s (spovs) related protein; PDBTitle: stage v sporolation protein s (spovs) from thermus thermophilus zinc2 form 96 c2rdpA_ not modelled 8.1 10 PDB header:transcription Chain: A: PDB Molecule:putative transcriptional regulator marr; PDBTitle: the structure of a marr family protein from bacillus2 stearothermophilus 97 c2veeC_ not modelled 8.0 13 PDB header:transport protein Chain: C: PDB Molecule:protoglobin; PDBTitle: structure of protoglobin from methanosarcina acetivorans2 c2a 98 c2l6pA_ not modelled 7.9 19 PDB header:structure genomics, unknown function Chain: A: PDB Molecule:phac1, phac2 and phad genes; PDBTitle: nmr solution structure of the protein np_253742.1 99 c3g3zA_ not modelled 7.8 24 PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator, marr family; PDBTitle: the structure of nmb1585, a marr family regulator from neisseria2 meningitidis

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0