Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	P	R	R	Y	N	P	D	T	R	R	D	E	L	L	E	R	I	N	L	D	I	P	G	A	V	A	Q	A	L	R	E	D	L	G	G	T	V	D	A	N	N	D	I	T	A	K	L	L	P	E	N	S	R	S	H	A	T	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																												?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		I	T	R	E	N	G	V	F	C	G	K	R	W	V	E	E	V	F	I	Q	L	A	G	D	D	V	T	I	I	W	H	V	D	D	G	D	V	I	N	A	N	Q	S	L	F	E	L	E	G	P	S	R	V	L	L	T	G	E	R	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	L	N	F	V	Q	T	L	S	G	V	A	S	K	V	R	H	Y	V	E	L	L	E	G	T	N	T	Q	L	L	D	T	R	K	T	L	P	G	L	R	S	A	L	K	Y	A	V	L	C	G	G	G	A	N	H	R	L	G	L	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	A	F	L	I	K	E	N	H	I	I	A	S	G	S	V	R	Q	A	V	E	K	A	S	W	L	H	P	D	A	P	V	E	V	E	V	E	N	L	E	E	L	D	E	A	L	K	A	G	A	D	I	I	M	L	D	N	F	E	T
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.
Sequence		E	Q	M	R	E	A	V	K	R	T	N	G	K	A	L	L	E	V	S	G	N	V	T	D	K	T	L	R	E	F	A	E	T	G	V	D	F	I	S	V	G	A	L	T	K	H	V	Q	A	L	D	L	S	M	R	F	R
Secondary structure
SS confidence
Disorder																																																				?					?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3paj chain A Region: 5 - 297 Aligned: 292 Modelled: 293 Confidence: 100.0% Identity: 62% PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 Phyre2 PDB 1qap chain A Region: 9 - 296 Aligned: 288 Modelled: 288 Confidence: 100.0% Identity: 86% PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid Phyre2 PDB 3l0g chain D Region: 23 - 297 Aligned: 270 Modelled: 271 Confidence: 100.0% Identity: 39% PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution Phyre2 PDB 1qpo chain A Region: 17 - 296 Aligned: 275 Modelled: 280 Confidence: 100.0% Identity: 42% PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis Phyre2 PDB 2b7p chain A Region: 22 - 296 Aligned: 267 Modelled: 275 Confidence: 100.0% Identity: 36% PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori Phyre2 PDB 1x1o chain C Region: 20 - 296 Aligned: 271 Modelled: 277 Confidence: 100.0% Identity: 48% PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 Phyre2 PDB 3tqv chain A Region: 20 - 297 Aligned: 267 Modelled: 278 Confidence: 100.0% Identity: 50% PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. Phyre2 PDB 2jbm chain A Region: 20 - 296 Aligned: 268 Modelled: 274 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human Phyre2 PDB 3gnn chain A Region: 17 - 296 Aligned: 248 Modelled: 261 Confidence: 100.0% Identity: 50% PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei Phyre2 PDB 3c2v chain A Region: 20 - 296 Aligned: 251 Modelled: 262 Confidence: 100.0% Identity: 33% PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of the quinolinate phosphoribosyl2 transferase (bna6) from saccharomyces cerevisiae complexed3 with prpp and the inhibitor phthalate Phyre2 PDB 1o4u chain A Region: 21 - 297 Aligned: 259 Modelled: 277 Confidence: 100.0% Identity: 34% PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution Phyre2 PDB 1ytk chain A Region: 13 - 296 Aligned: 265 Modelled: 269 Confidence: 100.0% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase from thermoplasma PDBTitle: crystal structure of a nicotinate phosphoribosyltransferase from2 thermoplasma acidophilum with nicotinate mononucleotide Phyre2 PDB 1qap chain A domain 1 Region: 131 - 296 Aligned: 166 Modelled: 166 Confidence: 100.0% Identity: 89% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1qpo chain A domain 1 Region: 131 - 296 Aligned: 166 Modelled: 166 Confidence: 100.0% Identity: 48% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 2i14 chain B Region: 13 - 296 Aligned: 264 Modelled: 269 Confidence: 100.0% Identity: 20% PDB header:transferase Chain: B: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from pyrococcus furiosus Phyre2 PDB 1o4u chain A domain 1 Region: 131 - 297 Aligned: 157 Modelled: 167 Confidence: 100.0% Identity: 41% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 2f7f chain A Region: 51 - 296 Aligned: 243 Modelled: 246 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase, putative; PDBTitle: crystal structure of enterococcus faecalis putative nicotinate2 phosphoribosyltransferase, new york structural genomics consortium Phyre2 PDB 1qap chain A domain 2 Region: 9 - 130 Aligned: 122 Modelled: 122 Confidence: 100.0% Identity: 83% Fold: alpha/beta-Hammerhead Superfamily: Nicotinate/Quinolinate PRTase N-terminal domain-like Family: NadC N-terminal domain-like Phyre2 PDB 2i14 chain A domain 1 Region: 127 - 296 Aligned: 169 Modelled: 170 Confidence: 100.0% Identity: 18% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 PDB 1ytd chain A domain 1 Region: 132 - 296 Aligned: 165 Modelled: 165 Confidence: 100.0% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Nicotinate/Quinolinate PRTase C-terminal domain-like Family: NadC C-terminal domain-like Phyre2 1 c3pajA_ 2 c1qapA_ 3 c3l0gD_ 4 c1qpoA_ 5 c2b7pA_ 6 c1x1oC_ 7 c3tqvA_ 8 c2jbmA_ 9 c3gnnA_ 10 c3c2vA_ 11 c1o4uA_ 12 c1ytkA_ 13 d1qapa1 14 d1qpoa1 15 c2i14B_ 16 d1o4ua1 17 c2f7fA_ 18 d1qapa2 19 d2i14a1 20 d1ytda1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499