Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP30140
DateThu Jan 5 11:46:06 GMT 2012
Unique Job ID85bc922a2c454d0c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3cixA_
Top template information
PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
Confidence and coverage
Confidence:100.0% Coverage: 89%
336 residues ( 89% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAASGYLEQLAQR
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   .........70.........80.........90.........100.........110.........120
Sequence  AQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKRKTLDEADIARESAAIREM
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   .........130.........140.........150.........160.........170.........180
Sequence  GFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQPLAETEYAELKQLGLDGVMV
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   .........190.........200.........210.........220.........230.........240
Sequence  YQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGIDKIGLGALIGLSDNWRVDSYMVA
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   .........250.........260.........270.........280.........290.........300
Sequence  EHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLST
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   .........310.........320.........330.........340.........350.........360
Sequence  RESPWFRDRVIPLAINNVSAFSKTQPGGYADNHPELEQFSPHDDRRPEAVAAALTAQGLQ
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   .........370.......
Sequence  PVWKDWDSYLGRASQRL
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?????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3cix chain A

3D model

Region: 24 - 373
Aligned: 336
Modelled: 350
Confidence: 100.0%
Identity: 19%
PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate

Phyre2

PDB 3t7v chain A

3D model

Region: 28 - 370
Aligned: 330
Modelled: 343
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)

Phyre2

PDB 1r30 chain A

3D model

Region: 35 - 363
Aligned: 304
Modelled: 329
Confidence: 100.0%
Identity: 18%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: Biotin synthase

Phyre2

PDB 1r30 chain A

3D model

Region: 35 - 363
Aligned: 304
Modelled: 329
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: A: PDB Molecule:biotin synthase;
PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme

Phyre2

PDB 1olt chain A

3D model

Region: 48 - 288
Aligned: 228
Modelled: 239
Confidence: 99.9%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: Oxygen-independent coproporphyrinogen III oxidase HemN

Phyre2

PDB 1tv8 chain A

3D model

Region: 67 - 285
Aligned: 207
Modelled: 219
Confidence: 99.7%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: MoCo biosynthesis proteins

Phyre2

PDB 2qgq chain F

3D model

Region: 89 - 269
Aligned: 170
Modelled: 177
Confidence: 99.6%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:protein tm_1862;
PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77

Phyre2

PDB 3rfa chain A

3D model

Region: 69 - 288
Aligned: 202
Modelled: 220
Confidence: 99.5%
Identity: 11%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n;
PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine

Phyre2

PDB 3c8f chain A

3D model

Region: 70 - 288
Aligned: 205
Modelled: 212
Confidence: 99.3%
Identity: 11%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme;
PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet

Phyre2

PDB 2yx0 chain A

3D model

Region: 79 - 243
Aligned: 163
Modelled: 165
Confidence: 99.2%
Identity: 12%
PDB header:metal binding protein
Chain: A: PDB Molecule:radical sam enzyme;
PDBTitle: crystal structure of p. horikoshii tyw1

Phyre2

PDB 2a5h chain C

3D model

Region: 67 - 288
Aligned: 195
Modelled: 209
Confidence: 99.0%
Identity: 16%
PDB header:isomerase
Chain: C: PDB Molecule:l-lysine 2,3-aminomutase;
PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate).

Phyre2

PDB 2ftp chain A

3D model

Region: 92 - 361
Aligned: 249
Modelled: 257
Confidence: 98.4%
Identity: 14%
PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa

Phyre2

PDB 2cw6 chain B

3D model

Region: 92 - 361
Aligned: 249
Modelled: 254
Confidence: 98.4%
Identity: 11%
PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria

Phyre2

PDB 1ydo chain C

3D model

Region: 92 - 361
Aligned: 253
Modelled: 256
Confidence: 98.2%
Identity: 9%
PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.

Phyre2

PDB 1ydn chain A

3D model

Region: 92 - 361
Aligned: 250
Modelled: 260
Confidence: 98.2%
Identity: 12%
PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.

Phyre2

PDB 3ble chain A

3D model

Region: 92 - 361
Aligned: 245
Modelled: 255
Confidence: 98.1%
Identity: 9%
PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate

Phyre2

PDB 3can chain A

3D model

Region: 125 - 288
Aligned: 147
Modelled: 164
Confidence: 97.9%
Identity: 15%
PDB header:lyase activator
Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme;
PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482

Phyre2

PDB 2z2u chain A

3D model

Region: 85 - 243
Aligned: 147
Modelled: 159
Confidence: 97.8%
Identity: 14%
PDB header:metal binding protein
Chain: A: PDB Molecule:upf0026 protein mj0257;
PDBTitle: crystal structure of archaeal tyw1

Phyre2

PDB 1nvm chain G

3D model

Region: 92 - 361
Aligned: 225
Modelled: 246
Confidence: 97.6%
Identity: 11%
PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate

Phyre2

PDB 3ivu chain B

3D model

Region: 92 - 358
Aligned: 228
Modelled: 246
Confidence: 97.2%
Identity: 11%
PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og

Phyre2
1

c3cixA_
2

c3t7vA_
3

d1r30a_
4

c1r30A_
5

d1olta_
6

d1tv8a_
7

c2qgqF_
8

c3rfaA_
9

c3c8fA_
10

c2yx0A_
11

c2a5hC_
12

c2ftpA_
13

c2cw6B_
14

c1ydoC_
15

c1ydnA_
16

c3bleA_
17

c3canA_
18

c2z2uA_
19

c1nvmG_
20

c3ivuB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3cixA_



100.0 19 PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
2c3t7vA_



100.0 21 PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)
3d1r30a_



100.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Biotin synthase
4c1r30A_



100.0 18 PDB header:transferase
Chain: A: PDB Molecule:biotin synthase;
PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme
5d1olta_



99.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Oxygen-independent coproporphyrinogen III oxidase HemN
6d1tv8a_



99.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:MoCo biosynthesis proteins
7c2qgqF_



99.6 12 PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:protein tm_1862;
PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77
8c3rfaA_



99.5 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n;
PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine
9c3c8fA_



99.3 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme;
PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet
10c2yx0A_



99.2 12 PDB header:metal binding protein
Chain: A: PDB Molecule:radical sam enzyme;
PDBTitle: crystal structure of p. horikoshii tyw1
11c2a5hC_



99.0 16 PDB header:isomerase
Chain: C: PDB Molecule:l-lysine 2,3-aminomutase;
PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate).
12c2ftpA_



98.4 14 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa
13c2cw6B_



98.4 11 PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
14c1ydoC_



98.2 9 PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.
15c1ydnA_



98.2 12 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.
16c3bleA_



98.1 9 PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate
17c3canA_



97.9 15 PDB header:lyase activator
Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme;
PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482
18c2z2uA_



97.8 14 PDB header:metal binding protein
Chain: A: PDB Molecule:upf0026 protein mj0257;
PDBTitle: crystal structure of archaeal tyw1
19c1nvmG_



97.6 11 PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
20c3ivuB_



97.2 11 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
21c3chvA_



not modelled 97.2 9 PDB header:metal binding protein
Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim
PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution
22d1ka9f_



not modelled 97.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
23c3no5C_



not modelled 96.9 13 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution
24c2y7eA_



not modelled 96.8 10 PDB header:lyase
Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme;
PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form)
25d1nvma2



not modelled 96.8 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
26c1sr9A_



not modelled 96.7 10 PDB header:transferase
Chain: A: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of leua from mycobacterium tuberculosis
27c3e02A_



not modelled 96.6 15 PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein duf849;
PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution
28d1tx2a_



not modelled 96.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
29c1tx2A_



not modelled 96.6 14 PDB header:transferase
Chain: A: PDB Molecule:dhps, dihydropteroate synthase;
PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis
30c3e49A_



not modelled 96.3 9 PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold;
PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution
31c2vefB_



not modelled 96.1 15 PDB header:transferase
Chain: B: PDB Molecule:dihydropteroate synthase;
PDBTitle: dihydropteroate synthase from streptococcus pneumoniae
32d1ajza_



not modelled 96.0 18 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
33c3lotC_



not modelled 95.8 12 PDB header:structure genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution
34c3oa3A_



not modelled 95.6 9 PDB header:lyase
Chain: A: PDB Molecule:aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis
35d1wbha1



not modelled 95.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
36c3labA_



not modelled 95.6 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
37d1ub3a_



not modelled 95.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
38c3hpxB_



not modelled 95.5 10 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644)
39d1mzha_



not modelled 95.5 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
40c3inpA_



not modelled 95.2 13 PDB header:isomerase
Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase;
PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis.
41d1eyea_



not modelled 95.2 19 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
42c1zfjA_



not modelled 95.2 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine monophosphate dehydrogenase;
PDBTitle: inosine monophosphate dehydrogenase (impdh; ec 1.1.1.205) from2 streptococcus pyogenes
43d1n7ka_



not modelled 95.2 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
44d1o0ya_



not modelled 95.2 9 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
45c3c6cA_



not modelled 95.0 11 PDB header:hydrolase
Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme;
PDBTitle: crystal structure of a putative 3-keto-5-aminohexanoate cleavage2 enzyme (reut_c6226) from ralstonia eutropha jmp134 at 1.72 a3 resolution
46c3ewbX_



not modelled 95.0 8 PDB header:transferase
Chain: X: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes
47d1h1ya_



not modelled 95.0 16 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
48c3k13A_



not modelled 95.0 13 PDB header:transferase
Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase;
PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron
49d1thfd_



not modelled 95.0 11 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
50d1sr9a2



not modelled 94.9 8 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
51c2yciX_



not modelled 94.8 14 PDB header:transferase
Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein
PDBTitle: methyltransferase native
52d1f6ya_



not modelled 94.7 15 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Methyltetrahydrofolate-utiluzing methyltransferases
53c3ngjC_



not modelled 94.7 8 PDB header:lyase
Chain: C: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica
54d1tqja_



not modelled 94.6 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
55d2flia1



not modelled 94.6 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
56c2bdqA_



not modelled 94.4 12 PDB header:metal transport
Chain: A: PDB Molecule:copper homeostasis protein cutc;
PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15.
57c3gr7A_



not modelled 94.4 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadph dehydrogenase;
PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form
58c2bmbA_



not modelled 94.2 16 PDB header:transferase
Chain: A: PDB Molecule:folic acid synthesis protein fol1;
PDBTitle: x-ray structure of the bifunctional 6-hydroxymethyl-7,8-2 dihydroxypterin pyrophosphokinase dihydropteroate synthase3 from saccharomyces cerevisiae
59d1ad1a_



not modelled 94.1 17 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Dihydropteroate synthetase
60c3eegB_



not modelled 94.1 9 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii
61d1h7na_



not modelled 94.0 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
62c2zyfA_



not modelled 93.9 11 PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate
63c3bolB_



not modelled 93.4 16 PDB header:transferase
Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine
PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+
64c3hf3A_



not modelled 93.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:chromate reductase;
PDBTitle: old yellow enzyme from thermus scotoductus sa-01
65d1rpxa_



not modelled 93.3 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
66c1rr2A_



not modelled 93.3 15 PDB header:transferase
Chain: A: PDB Molecule:transcarboxylase 5s subunit;
PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid
67d2c1ha1



not modelled 92.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
68d1tqxa_



not modelled 92.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:D-ribulose-5-phosphate 3-epimerase
69d3bofa1



not modelled 92.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Dihydropteroate synthetase-like
Family:Methyltetrahydrofolate-utiluzing methyltransferases
70c3bg3B_



not modelled 92.6 13 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial;
PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus)
71c1qpoA_



not modelled 92.3 16 PDB header:transferase
Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase;
PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis
72d1h5ya_



not modelled 92.2 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
73d1vhca_



not modelled 92.1 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
74c3tr9A_



not modelled 92.0 17 PDB header:transferase
Chain: A: PDB Molecule:dihydropteroate synthase;
PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii
75c2nx9B_



not modelled 92.0 15 PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae
76d1qo2a_



not modelled 91.8 15 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
77c3tdmD_



not modelled 91.8 13 PDB header:de novo protein
Chain: D: PDB Molecule:computationally designed two-fold symmetric tim-barrel
PDBTitle: computationally designed tim-barrel protein, halfflr
78d1gzga_



not modelled 91.8 22 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
79c2jbmA_



not modelled 91.7 17 PDB header:transferase
Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase;
PDBTitle: qprtase structure from human
80d1vcva1



not modelled 91.7 10 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
81d1rqba2



not modelled 91.7 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
82d1m5wa_



not modelled 91.4 13 Fold:TIM beta/alpha-barrel
Superfamily:Pyridoxine 5'-phosphate synthase
Family:Pyridoxine 5'-phosphate synthase
83d1ps9a1



not modelled 91.3 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
84d1l6sa_



not modelled 91.3 18 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
85d1z41a1



not modelled 91.2 19 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
86c2b7pA_



not modelled 90.8 9 PDB header:transferase
Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase;
PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori
87c3gk0H_



not modelled 90.6 17 PDB header:transferase
Chain: H: PDB Molecule:pyridoxine 5'-phosphate synthase;
PDBTitle: crystal structure of pyridoxal phosphate biosynthetic2 protein from burkholderia pseudomallei
88c1o4uA_



not modelled 90.2 11 PDB header:transferase
Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase;
PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution
89d1mxsa_



not modelled 90.2 17 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
90c1ps9A_



not modelled 90.1 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:2,4-dienoyl-coa reductase;
PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase
91c3qc3B_



not modelled 89.6 16 PDB header:isomerase
Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase;
PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution
92d1qpoa1



not modelled 89.6 16 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
93c3ct7E_



not modelled 89.5 13 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
94d1pv8a_



not modelled 89.5 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)
95c2h90A_



not modelled 89.0 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:xenobiotic reductase a;
PDBTitle: xenobiotic reductase a in complex with coumarin
96c3ng3A_



not modelled 87.8 14 PDB header:lyase
Chain: A: PDB Molecule:deoxyribose-phosphate aldolase;
PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde
97d1o4ua1



not modelled 87.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
98d1vhna_



not modelled 87.2 12 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
99c3obkH_



not modelled 87.0 20 PDB header:lyase
Chain: H: PDB Molecule:delta-aminolevulinic acid dehydratase;
PDBTitle: crystal structure of delta-aminolevulinic acid dehydratase2 (porphobilinogen synthase) from toxoplasma gondii me49 in complex3 with the reaction product porphobilinogen
100d1p1xa_



not modelled 86.5 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
101c1djnB_



not modelled 86.2 7 PDB header:oxidoreductase
Chain: B: PDB Molecule:trimethylamine dehydrogenase;
PDBTitle: structural and biochemical characterization of recombinant wild type2 trimethylamine dehydrogenase from methylophilus methylotrophus (sp.3 w3a1)
102c2nuxB_



not modelled 85.8 23 PDB header:lyase
Chain: B: PDB Molecule:2-keto-3-deoxygluconate/2-keto-3-deoxy-6-phospho gluconate
PDBTitle: 2-keto-3-deoxygluconate aldolase from sulfolobus acidocaldarius,2 native structure in p6522 at 2.5 a resolution
103c2y5sA_



not modelled 84.9 14 PDB header:transferase
Chain: A: PDB Molecule:dihydropteroate synthase;
PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate.
104d1yxya1



not modelled 84.8 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:NanE-like
105c2w6rA_



not modelled 84.7 12 PDB header:lyase
Chain: A: PDB Molecule:imidazole glycerol phosphate synthase subunit
PDBTitle: crystal structure of an artificial (ba)8-barrel protein2 designed from identical half barrels
106d1qopa_



not modelled 84.6 9 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
107c3kruC_



not modelled 84.6 8 PDB header:oxidoreductase
Chain: C: PDB Molecule:nadh:flavin oxidoreductase/nadh oxidase;
PDBTitle: crystal structure of the thermostable old yellow enzyme from2 thermoanaerobacter pseudethanolicus e39
108d1vyra_



not modelled 84.3 13 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
109c3k30B_



not modelled 83.8 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:histamine dehydrogenase;
PDBTitle: histamine dehydrogenase from nocardiodes simplex
110c3r2gA_



not modelled 83.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:inosine 5'-monophosphate dehydrogenase;
PDBTitle: crystal structure of inosine 5' monophosphate dehydrogenase from2 legionella pneumophila
111c3iwpK_



not modelled 83.7 13 PDB header:metal binding protein
Chain: K: PDB Molecule:copper homeostasis protein cutc homolog;
PDBTitle: crystal structure of human copper homeostasis protein cutc
112c3dxiB_



not modelled 83.2 11 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative aldolase;
PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus
113c2p0oA_



not modelled 82.8 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein duf871;
PDBTitle: crystal structure of a conserved protein from locus ef_2437 in2 enterococcus faecalis with an unknown function
114c3gndC_



not modelled 82.5 15 PDB header:lyase
Chain: C: PDB Molecule:aldolase lsrf;
PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate
115d1qapa1



not modelled 82.1 18 Fold:TIM beta/alpha-barrel
Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like
Family:NadC C-terminal domain-like
116c2fmoA_



not modelled 82.1 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate reductase;
PDBTitle: ala177val mutant of e. coli methylenetetrahydrofolate2 reductase
117c3daqB_



not modelled 82.1 15 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus
118d1rvka1



not modelled 81.9 13 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:D-glucarate dehydratase-like
119d1x7fa2



not modelled 81.5 15 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Outer surface protein, N-terminal domain
120d1gvfa_



not modelled 81.5 13 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0