Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	S	T	P	K	K	A	P	R	S	K	F	P	A	L	L	V	V	A	L	A	L	V	A	L	V	F	V	I	W	R	V	D	S	A	P	S	T	N	D	A	Y	A	S	A	D	T	I	D	V	V	P	E	V	S	G	R	I	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?																									?																				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		E	L	A	V	T	D	N	Q	A	V	K	Q	G	D	L	L	F	R	I	D	P	R	P	Y	E	A	N	L	A	K	A	E	A	S	L	A	A	L	D	K	Q	I	M	L	T	Q	R	S	V	D	A	Q	Q	F	G	A	D	S	V	N
Secondary structure
SS confidence
Disorder																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	T	V	E	K	A	R	A	A	A	K	Q	A	T	D	T	L	R	R	T	E	P	L	L	K	E	G	F	V	S	A	E	D	V	D	R	A	R	T	A	Q	R	A	A	E	A	D	L	N	A	V	L	L	Q	A	Q	S	A	A	S
Secondary structure
SS confidence
Disorder																											?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	V	S	G	V	D	A	L	V	A	Q	R	A	A	V	E	A	D	I	A	L	T	K	L	H	L	E	M	A	T	V	R	A	P	F	D	G	R	V	I	S	L	K	T	S	V	G	Q	F	A	S	A	M	R	P	I	F	T	L	I
Secondary structure
SS confidence
Disorder																																																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		D	T	R	H	W	Y	V	I	A	N	F	R	E	T	D	L	K	N	I	R	S	G	T	P	A	T	I	R	L	M	S	D	S	G	K	T	F	E	G	K	V	D	S	I	G	Y	G	V	L	P	D	D	G	G	L	V	L	G	G	L
Secondary structure
SS confidence
Disorder																				?	?																											?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.
Sequence		P	K	V	S	R	S	I	N	W	V	R	V	A	Q	R	F	P	V	K	I	M	V	D	K	P	D	P	E	M	F	R	I	G	A	S	A	V	A	N	L	E	P	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?																					?	?	?													?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fpp chain B Region: 32 - 343 Aligned: 254 Modelled: 255 Confidence: 100.0% Identity: 27% PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca Phyre2 PDB 2f1m chain A Region: 41 - 341 Aligned: 222 Modelled: 228 Confidence: 99.9% Identity: 23% PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra Phyre2 PDB 3lnn chain B Region: 37 - 343 Aligned: 237 Modelled: 239 Confidence: 99.9% Identity: 30% PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans Phyre2 PDB 1t5e chain B Region: 41 - 340 Aligned: 212 Modelled: 213 Confidence: 99.9% Identity: 26% PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa Phyre2 PDB 1vf7 chain A Region: 38 - 342 Aligned: 217 Modelled: 218 Confidence: 99.9% Identity: 27% Fold: HlyD-like secretion proteins Superfamily: HlyD-like secretion proteins Family: HlyD-like secretion proteins Phyre2 PDB 3h9i chain B Region: 32 - 343 Aligned: 215 Modelled: 216 Confidence: 99.9% Identity: 18% PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli Phyre2 PDB 2k33 chain A Region: 49 - 255 Aligned: 113 Modelled: 113 Confidence: 99.4% Identity: 29% PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation Phyre2 PDB 2b8g chain A Region: 50 - 244 Aligned: 72 Modelled: 72 Confidence: 98.0% Identity: 32% PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) Phyre2 PDB 1o78 chain A Region: 51 - 239 Aligned: 66 Modelled: 66 Confidence: 97.7% Identity: 29% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1dcz chain A Region: 50 - 239 Aligned: 67 Modelled: 67 Confidence: 97.7% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejg chain D Region: 50 - 239 Aligned: 67 Modelled: 67 Confidence: 97.7% Identity: 22% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 3n6r chain K Region: 50 - 81 Aligned: 32 Modelled: 32 Confidence: 97.0% Identity: 28% PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) Phyre2 PDB 2dn8 chain A Region: 50 - 81 Aligned: 32 Modelled: 32 Confidence: 97.0% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase Phyre2 PDB 2ejm chain A Region: 51 - 81 Aligned: 31 Modelled: 31 Confidence: 96.9% Identity: 26% PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase Phyre2 PDB 2kcc chain A Region: 51 - 81 Aligned: 31 Modelled: 31 Confidence: 96.9% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 Phyre2 PDB 2l5t chain A Region: 48 - 81 Aligned: 34 Modelled: 34 Confidence: 96.8% Identity: 32% PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum Phyre2 PDB 1iyu chain A Region: 48 - 83 Aligned: 36 Modelled: 36 Confidence: 96.7% Identity: 19% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1bdo chain A Region: 48 - 80 Aligned: 33 Modelled: 33 Confidence: 96.7% Identity: 21% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1ghj chain A Region: 48 - 82 Aligned: 35 Modelled: 35 Confidence: 96.5% Identity: 26% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1k8m chain A Region: 48 - 83 Aligned: 36 Modelled: 36 Confidence: 96.4% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 1 c3fppB_ 2 c2f1mA_ 3 c3lnnB_ 4 c1t5eB_ 5 d1vf7a_ 6 c3h9iB_ 7 c2k33A_ 8 c2b8gA_ 9 d1o78a_ 10 d1dcza_ 11 c2ejgD_ 12 c3n6rK_ 13 c2dn8A_ 14 c2ejmA_ 15 c2kccA_ 16 c2l5tA_ 17 d1iyua_ 18 d1bdoa_ 19 d1ghja_ 20 d1k8ma_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fppB_ 100.0 27 PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca 2 c2f1mA_ 99.9 23 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 3 c3lnnB_ 99.9 30 PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans 4 c1t5eB_ 99.9 26 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 5 d1vf7a_ 99.9 27 Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins 6 c3h9iB_ 99.9 18 PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli 7 c2k33A_ 99.4 29 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 8 c2b8gA_ 98.0 32 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 9 d1o78a_ 97.7 29 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 10 d1dcza_ 97.7 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 11 c2ejgD_ 97.7 22 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 12 c3n6rK_ 97.0 28 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 13 c2dn8A_ 97.0 16 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 14 c2ejmA_ 96.9 26 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 15 c2kccA_ 96.9 16 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 16 c2l5tA_ 96.8 32 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 17 d1iyua_ 96.7 19 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 18 d1bdoa_ 96.7 21 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 19 d1ghja_ 96.5 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 20 d1k8ma_ 96.4 17 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 21 d1qjoa_ not modelled 96.3 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 22 d1laba_ not modelled 96.2 22 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 23 d1gjxa_ not modelled 95.9 29 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 24 d1y8ob1 not modelled 95.8 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 25 d2pnrc1 not modelled 95.5 21 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 26 d1glaf_ not modelled 95.5 43 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 27 c2q8iB_ not modelled 95.3 22 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 28 d1gpra_ not modelled 95.3 34 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 29 d2gpra_ not modelled 95.3 39 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 30 c2qf7A_ not modelled 95.3 26 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 31 d2f3ga_ not modelled 95.2 42 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 32 d1pmra_ not modelled 95.2 15 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 33 c2dncA_ not modelled 94.6 14 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 34 c2jkuA_ not modelled 94.6 23 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 35 c2dneA_ not modelled 94.1 13 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 36 d1brwa3 not modelled 92.7 31 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 37 d2tpta3 not modelled 92.6 20 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 38 d1uoua3 not modelled 92.5 22 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 39 c2gu1A_ not modelled 91.9 14 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 40 c2hsiB_ not modelled 91.5 24 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 41 c2dsjA_ not modelled 89.0 26 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 42 c3h5qA_ not modelled 88.9 30 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 43 c2j0fC_ not modelled 88.7 28 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 44 c1brwB_ not modelled 87.0 31 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 45 c1otpA_ not modelled 87.0 22 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 46 c3nyyA_ not modelled 86.4 18 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 47 c2aukA_ not modelled 85.4 35 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 48 c3fmcC_ not modelled 84.4 11 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 49 d1qwya_ not modelled 84.1 26 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 50 c2qj8B_ not modelled 83.3 19 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 51 d1wp1a_ not modelled 82.1 17 Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP) 52 c3pikA_ not modelled 81.1 16 PDB header:transport protein Chain: A: PDB Molecule:cation efflux system protein cusc; PDBTitle: outer membrane protein cusc 53 d1qpoa2 not modelled 80.5 29 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 54 d1ci3m2 not modelled 80.2 38 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 55 d1e2wa2 not modelled 79.2 31 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 56 c2xhaB_ not modelled 78.4 33 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg) 57 c1yc9A_ not modelled 76.1 15 PDB header:membrane protein Chain: A: PDB Molecule:multidrug resistance protein; PDBTitle: the crystal structure of the outer membrane protein vcec from the2 bacterial pathogen vibrio cholerae at 1.8 resolution 58 c3na6A_ not modelled 76.0 22 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 59 c2b44A_ not modelled 76.0 26 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 60 d1o4ua2 not modelled 75.5 14 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 61 c3ojaB_ not modelled 75.2 12 PDB header:protein binding Chain: B: PDB Molecule:anopheles plasmodium-responsive leucine-rich repeat protein PDBTitle: crystal structure of lrim1/apl1c complex 62 c1tqqC_ not modelled 74.4 13 PDB header:transport protein Chain: C: PDB Molecule:outer membrane protein tolc; PDBTitle: structure of tolc in complex with hexamminecobalt 63 d1y14b1 not modelled 74.2 13 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 64 d1ek9a_ not modelled 73.7 12 Fold:Outer membrane efflux proteins (OEP) Superfamily:Outer membrane efflux proteins (OEP) Family:Outer membrane efflux proteins (OEP) 65 d1qapa2 not modelled 72.5 20 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 66 c3cdxB_ not modelled 71.9 16 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 67 c2xhcA_ not modelled 71.5 33 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of thermotoga maritima n-utilization substance g2 (nusg) 68 d2ix0a1 not modelled 70.7 12 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 69 c2aujD_ not modelled 68.0 22 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 70 d1fr3a_ not modelled 67.3 17 Fold:OB-fold Superfamily:MOP-like Family:Molybdate/tungstate binding protein MOP 71 c1h9sA_ not modelled 67.2 13 PDB header:transcription regulator Chain: A: PDB Molecule:molybdenum transport protein mode; PDBTitle: molybdate bound complex of dimop domain of mode from e.coli 72 c3it5B_ not modelled 66.3 19 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 73 d1h9ma2 not modelled 63.9 20 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 74 c3gnnA_ not modelled 62.8 4 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide2 pyrophosphorylase from burkholderi pseudomallei 75 c1ctmA_ not modelled 62.5 31 PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation 76 c1e2vB_ not modelled 62.0 31 PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii 77 c2jxmB_ not modelled 61.4 44 PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex 78 c3d4rE_ not modelled 61.0 18 PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution 79 c1tu2B_ not modelled 60.1 50 PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures 80 c1qpoA_ not modelled 59.7 26 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 81 d1h9ma1 not modelled 59.7 19 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 82 c1q90A_ not modelled 58.6 31 PDB header:photosynthesis Chain: A: PDB Molecule:apocytochrome f; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 83 c1o4uA_ not modelled 58.4 16 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution 84 d1h9ra2 not modelled 56.8 13 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 85 c2e75C_ not modelled 56.4 56 PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus 86 c1h9mB_ not modelled 56.1 15 PDB header:binding protein Chain: B: PDB Molecule:molybdenum-binding-protein; PDBTitle: two crystal structures of the cytoplasmic molybdate-binding2 protein modg suggest a novel cooperative binding mechanism3 and provide insights into ligand-binding specificity.4 peg-grown form with molybdate bound 87 c2jbmA_ not modelled 55.6 6 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: qprtase structure from human 88 c3pajA_ not modelled 55.0 19 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase, carboxylating; PDBTitle: 2.00 angstrom resolution crystal structure of a quinolinate2 phosphoribosyltransferase from vibrio cholerae o1 biovar eltor str.3 n16961 89 c1qapA_ not modelled 54.9 20 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 90 d2c35b1 not modelled 54.1 10 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 91 c3tqvA_ not modelled 54.0 16 PDB header:transferase Chain: A: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: structure of the nicotinate-nucleotide pyrophosphorylase from2 francisella tularensis. 92 c3csqC_ not modelled 54.0 33 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 93 c2b7pA_ not modelled 53.3 17 PDB header:transferase Chain: A: PDB Molecule:probable nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of quinolinic acid phosphoribosyltransferase from2 helicobacter pylori 94 d1guta_ not modelled 53.0 22 Fold:OB-fold Superfamily:MOP-like Family:Molybdate/tungstate binding protein MOP 95 d1tu2b2 not modelled 52.7 56 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 96 c3l0gD_ not modelled 52.7 9 PDB header:transferase Chain: D: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of nicotinate-nucleotide pyrophosphorylase from2 ehrlichia chaffeensis at 2.05a resolution 97 d3d31a1 not modelled 47.5 19 Fold:OB-fold Superfamily:MOP-like Family:ABC-transporter additional domain 98 d1hcza2 not modelled 45.9 31 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 99 d1h9ra1 not modelled 44.5 12 Fold:OB-fold Superfamily:MOP-like Family:BiMOP, duplicated molybdate-binding domain 100 c1x1oC_ not modelled 44.1 13 PDB header:transferase Chain: C: PDB Molecule:nicotinate-nucleotide pyrophosphorylase; PDBTitle: crystal structure of project id tt0268 from thermus thermophilus hb8 101 c1y4cA_ not modelled 42.0 10 PDB header:de novo protein Chain: A: PDB Molecule:maltose binding protein fused with designed PDBTitle: designed helical protein fusion mbp 102 c2edgA_ not modelled 39.8 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: solution structure of the gcv_h domain from mouse glycine 103 c3iftA_ not modelled 39.6 20 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from2 mycobacterium tuberculosis, using x-rays from the compact light3 source. 104 d1onla_ not modelled 39.5 16 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 105 d2je6i2 not modelled 39.3 28 Fold:Barrel-sandwich hybrid Superfamily:Ribosomal L27 protein-like Family:ECR1 N-terminal domain-like 106 d1whla_ not modelled 37.8 21 Fold:SH3-like barrel Superfamily:Cap-Gly domain Family:Cap-Gly domain 107 c3e20A_ not modelled 37.2 17 PDB header:translation Chain: A: PDB Molecule:eukaryotic peptide chain release factor gtp-binding PDBTitle: crystal structure of s.pombe erf1/erf3 complex 108 c1deqF_ not modelled 35.9 6 PDB header: PDB COMPND: 109 d1q46a2 not modelled 35.7 16 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 110 c3mxuA_ not modelled 34.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae 111 c2khjA_ not modelled 34.3 25 PDB header:ribosomal protein Chain: A: PDB Molecule:30s ribosomal protein s1; PDBTitle: nmr structure of the domain 6 of the e. coli ribosomal2 protein s1 112 d1krha1 not modelled 33.7 18 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 113 d1hpca_ not modelled 32.6 16 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 114 c2gl2B_ not modelled 30.5 22 PDB header:cell adhesion Chain: B: PDB Molecule:adhesion a; PDBTitle: crystal structure of the tetra muntant (t66g,r67g,f68g,2 y69g) of bacterial adhesin fada 115 d1go3e1 not modelled 30.0 17 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 116 d1hh2p1 not modelled 29.9 18 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Cold shock DNA-binding domain-like 117 c3ghgK_ not modelled 29.3 12 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 118 c2jz2A_ not modelled 27.7 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ssl0352 protein; PDBTitle: solution nmr structure of ssl0352 protein from synechocystis sp. pcc2 6803. northeast structural genomics consortium target sgr42 119 d1vf5c2 not modelled 27.6 56 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 120 c3tbiB_ not modelled 27.5 36 PDB header:transcription Chain: B: PDB Molecule:dna-directed rna polymerase subunit beta; PDBTitle: crystal structure of t4 gp33 bound to e. coli rnap beta-flap domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0