Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	L	T	A	S	S	S	S	R	A	V	T	N	S	P	V	V	V	A	L	D	Y	H	N	R	D	D	A	L	A	F	V	D	K	I	D	P	R	D	C	R	L	K	V	G	K	E	M	F	T	L	F	G	P	Q	F	V	R	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	Q	Q	R	G	F	D	I	F	L	D	L	K	F	H	D	I	P	N	T	A	A	H	A	V	A	A	A	A	D	L	G	V	W	M	V	N	V	H	A	S	G	G	A	R	M	M	T	A	A	R	E	A	L	V	P	F	G	K	D
Secondary structure
SS confidence
Disorder																																											?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		A	P	L	L	I	A	V	T	V	L	T	S	M	E	A	S	D	L	V	D	L	G	M	T	L	S	P	A	D	Y	A	E	R	L	A	A	L	T	Q	K	C	G	L	D	G	V	V	C	S	A	Q	E	A	V	R	F	K	Q	V	F
Secondary structure
SS confidence
Disorder										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	Q	E	F	K	L	V	T	P	G	I	R	P	Q	G	S	E	A	G	D	Q	R	R	I	M	T	P	E	Q	A	L	S	A	G	V	D	Y	M	V	I	G	R	P	V	T	Q	S	V	D	P	A	Q	T	L	K	A	I	N	A	S
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?																									?		?
Disorder confidence
		.	.	.	.	.
Sequence		L	Q	R	S	A
Secondary structure
SS confidence
Disorder				?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1eix chain A Region: 12 - 242 Aligned: 231 Modelled: 231 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 1dbt chain A Region: 12 - 243 Aligned: 232 Modelled: 232 Confidence: 100.0% Identity: 39% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 3ldv chain B Region: 13 - 241 Aligned: 223 Modelled: 229 Confidence: 100.0% Identity: 69% PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961 Phyre2 PDB 3tr2 chain A Region: 14 - 241 Aligned: 218 Modelled: 228 Confidence: 100.0% Identity: 49% PDB header:lyase Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii Phyre2 PDB 2yyt chain A Region: 16 - 241 Aligned: 210 Modelled: 210 Confidence: 100.0% Identity: 40% PDB header:lyase Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus Phyre2 PDB 2qcn chain A Region: 10 - 244 Aligned: 219 Modelled: 235 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump Phyre2 PDB 3ru6 chain C Region: 16 - 242 Aligned: 216 Modelled: 218 Confidence: 100.0% Identity: 34% PDB header:lyase Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168 Phyre2 PDB 3tfx chain B Region: 14 - 242 Aligned: 218 Modelled: 229 Confidence: 100.0% Identity: 38% PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus Phyre2 PDB 3bvj chain A Region: 10 - 244 Aligned: 219 Modelled: 235 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp Phyre2 PDB 1dqw chain A Region: 10 - 244 Aligned: 225 Modelled: 235 Confidence: 100.0% Identity: 20% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 3qw3 chain B Region: 1 - 243 Aligned: 227 Modelled: 236 Confidence: 100.0% Identity: 20% PDB header:transferase, lyase Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate PDBTitle: structure of leishmania donovani omp decarboxylase Phyre2 PDB 1km4 chain A Region: 14 - 241 Aligned: 210 Modelled: 220 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 1dvj chain A Region: 15 - 244 Aligned: 212 Modelled: 222 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 3qw4 chain B Region: 1 - 243 Aligned: 225 Modelled: 236 Confidence: 100.0% Identity: 23% PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase Phyre2 PDB 2czd chain A domain 1 Region: 17 - 242 Aligned: 204 Modelled: 226 Confidence: 100.0% Identity: 24% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 2q8z chain A domain 1 Region: 1 - 243 Aligned: 235 Modelled: 243 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 1los chain C Region: 15 - 225 Aligned: 189 Modelled: 189 Confidence: 100.0% Identity: 25% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 2ffc chain A domain 1 Region: 8 - 244 Aligned: 228 Modelled: 237 Confidence: 100.0% Identity: 19% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 PDB 2fds chain A Region: 9 - 244 Aligned: 223 Modelled: 236 Confidence: 100.0% Identity: 17% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase; PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225) Phyre2 PDB 2fds chain A domain 1 Region: 9 - 244 Aligned: 223 Modelled: 236 Confidence: 100.0% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Ribulose-phoshate binding barrel Family: Decarboxylase Phyre2 1 d1eixa_ 2 d1dbta_ 3 c3ldvB_ 4 c3tr2A_ 5 c2yytA_ 6 c2qcnA_ 7 c3ru6C_ 8 c3tfxB_ 9 c3bvjA_ 10 d1dqwa_ 11 c3qw3B_ 12 d1km4a_ 13 d1dvja_ 14 c3qw4B_ 15 d2czda1 16 d2q8za1 17 d1losc_ 18 d2ffca1 19 c2fdsA_ 20 d2fdsa1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1eixa_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 2 d1dbta_ 100.0 39 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 3 c3ldvB_ 100.0 69 PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: 1.77 angstrom resolution crystal structure of orotidine 5'-2 phosphate decarboxylase from vibrio cholerae o1 biovar3 eltor str. n16961 4 c3tr2A_ 100.0 49 PDB header:lyase Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: structure of a orotidine 5'-phosphate decarboxylase (pyrf) from2 coxiella burnetii 5 c2yytA_ 100.0 40 PDB header:lyase Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of uncharacterized conserved protein from2 geobacillus kaustophilus 6 c2qcnA_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: covalent complex of the orotidine-5'-monophosphate decarboxylase2 domain of human ump synthase with 6-iodo-ump 7 c3ru6C_ 100.0 34 PDB header:lyase Chain: C: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: 1.8 angstrom resolution crystal structure of orotidine 5'-phosphate2 decarboxylase (pyrf) from campylobacter jejuni subsp. jejuni nctc3 11168 8 c3tfxB_ 100.0 38 PDB header:lyase Chain: B: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of orotidine 5'-phosphate decarboxylase from2 lactobacillus acidophilus 9 c3bvjA_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:uridine 5'-monophosphate synthase; PDBTitle: crystal structure of human orotidine 5'-monophosphate decarboxylase2 complexed with xmp 10 d1dqwa_ 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 11 c3qw3B_ 100.0 20 PDB header:transferase, lyase Chain: B: PDB Molecule:orotidine-5-phosphate decarboxylase/orotate PDBTitle: structure of leishmania donovani omp decarboxylase 12 d1km4a_ 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 13 d1dvja_ 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 14 c3qw4B_ 100.0 23 PDB header:transferase, lyase Chain: B: PDB Molecule:ump synthase; PDBTitle: structure of leishmania donovani ump synthase 15 d2czda1 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 16 d2q8za1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 17 d1losc_ 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 18 d2ffca1 100.0 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 19 c2fdsA_ 100.0 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:orotidine-monophosphate-decarboxylase; PDBTitle: crystal structure of plasmodium berghei orotidine 5'-2 monophosphate decarboxylase (ortholog of plasmodium3 falciparum pf10_0225) 20 d2fdsa1 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 21 c3l52A_ not modelled 100.0 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of putative orotidine 5'-phosphate2 decarboxylase from streptomyces avermitilis ma-4680 22 d1vqta1 not modelled 100.0 26 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 23 c3r89A_ not modelled 100.0 14 PDB header:lyase Chain: A: PDB Molecule:orotidine 5'-phosphate decarboxylase; PDBTitle: crystal structure of orotidine 5-phosphate decarboxylase from2 anaerococcus prevotii dsm 20548 24 c3exsB_ not modelled 100.0 18 PDB header:lyase Chain: B: PDB Molecule:rmpd (hexulose-6-phosphate synthase); PDBTitle: crystal structure of kgpdc from streptococcus mutans in2 complex with d-r5p 25 d1q6oa_ not modelled 100.0 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Decarboxylase 26 c3jr2D_ not modelled 100.0 14 PDB header:biosynthetic protein Chain: D: PDB Molecule:hexulose-6-phosphate synthase sgbh; PDBTitle: x-ray crystal structure of the mg-bound 3-keto-l-gulonate-6-phosphate2 decarboxylase from vibrio cholerae o1 biovar el tor str. n16961 27 c3ajxA_ not modelled 100.0 17 PDB header:lyase Chain: A: PDB Molecule:3-hexulose-6-phosphate synthase; PDBTitle: crystal structure of 3-hexulose-6-phosphate synthase 28 c3f4wA_ not modelled 100.0 19 PDB header:synthase, lyase Chain: A: PDB Molecule:putative hexulose 6 phosphate synthase; PDBTitle: the 1.65a crystal structure of 3-hexulose-6-phosphate2 synthase from salmonella typhimurium 29 c3ct7E_ not modelled 100.0 14 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 30 c3cu2A_ not modelled 100.0 11 PDB header:isomerase Chain: A: PDB Molecule:ribulose-5-phosphate 3-epimerase; PDBTitle: crystal structure of ribulose-5-phosphate 3-epimerase (yp_718263.1)2 from haemophilus somnus 129pt at 1.91 a resolution 31 d1h1ya_ not modelled 100.0 13 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 32 d1ojxa_ not modelled 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 33 c3qc3B_ not modelled 100.0 16 PDB header:isomerase Chain: B: PDB Molecule:d-ribulose-5-phosphate-3-epimerase; PDBTitle: crystal structure of a d-ribulose-5-phosphate-3-epimerase (np_954699)2 from homo sapiens at 2.20 a resolution 34 c3inpA_ not modelled 99.9 13 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 35 d2flia1 not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 36 d1rpxa_ not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 37 d1tqxa_ not modelled 99.9 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 38 c2qjhH_ not modelled 99.9 15 PDB header:lyase Chain: H: PDB Molecule:putative aldolase mj0400; PDBTitle: m. jannaschii adh synthase covalently bound to2 dihydroxyacetone phosphate 39 c3gndC_ not modelled 99.9 17 PDB header:lyase Chain: C: PDB Molecule:aldolase lsrf; PDBTitle: crystal structure of e. coli lsrf in complex with ribulose-5-phosphate 40 d1tqja_ not modelled 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:D-ribulose-5-phosphate 3-epimerase 41 c3thaB_ not modelled 99.4 13 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: tryptophan synthase subunit alpha from campylobacter jejuni. 42 d1wbha1 not modelled 99.4 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 43 d1wa3a1 not modelled 99.3 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 44 c2ekcA_ not modelled 99.3 10 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 45 d1xcfa_ not modelled 99.3 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 46 d1qopa_ not modelled 99.2 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 47 c2bdqA_ not modelled 99.2 14 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 48 d1rd5a_ not modelled 99.2 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 49 c2v82A_ not modelled 99.1 15 PDB header:lyase Chain: A: PDB Molecule:2-dehydro-3-deoxy-6-phosphogalactonate aldolase; PDBTitle: kdpgal complexed to kdpgal 50 d1j5ta_ not modelled 99.1 18 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 51 c3navB_ not modelled 99.1 21 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 52 d1geqa_ not modelled 99.0 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 53 d1vhca_ not modelled 99.0 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 54 c3qjaA_ not modelled 99.0 12 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of the mycobacterium tuberculosis indole-3-glycerol2 phosphate synthase (trpc) in apo form 55 d1piia2 not modelled 99.0 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 56 c3igsB_ not modelled 99.0 16 PDB header:isomerase Chain: B: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase 2; PDBTitle: structure of the salmonella enterica n-acetylmannosamine-6-phosphate2 2-epimerase 57 d1mxsa_ not modelled 99.0 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 58 d1i4na_ not modelled 98.9 19 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 59 d2tpsa_ not modelled 98.9 16 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 60 c3labA_ not modelled 98.9 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate) PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica 61 c2c3zA_ not modelled 98.8 15 PDB header:lyase Chain: A: PDB Molecule:indole-3-glycerol phosphate synthase; PDBTitle: crystal structure of a truncated variant of indole-3-2 glycerol phosphate synthase from sulfolobus solfataricus 62 c3o63B_ not modelled 98.8 15 PDB header:transferase Chain: B: PDB Molecule:probable thiamine-phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamin phosphate synthase from mycobacterium2 tuberculosis 63 c3q58A_ not modelled 98.8 14 PDB header:isomerase Chain: A: PDB Molecule:n-acetylmannosamine-6-phosphate 2-epimerase; PDBTitle: structure of n-acetylmannosamine-6-phosphate epimerase from salmonella2 enterica 64 c1yadD_ not modelled 98.7 15 PDB header:transcription Chain: D: PDB Molecule:regulatory protein teni; PDBTitle: structure of teni from bacillus subtilis 65 d1xi3a_ not modelled 98.7 16 Fold:TIM beta/alpha-barrel Superfamily:Thiamin phosphate synthase Family:Thiamin phosphate synthase 66 d1y0ea_ not modelled 98.7 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 67 d1ujpa_ not modelled 98.7 17 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 68 d1yxya1 not modelled 98.6 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:NanE-like 69 c2yw3E_ not modelled 98.6 15 PDB header:lyase Chain: E: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- PDBTitle: crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-2 deydro-3-deoxyphosphogluconate aldolase from tthb1 70 d1thfd_ not modelled 98.6 12 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 71 d1a53a_ not modelled 98.6 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 72 d1znna1 not modelled 98.6 15 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:PdxS-like 73 d1wv2a_ not modelled 98.6 19 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 74 c3fokH_ not modelled 98.5 16 PDB header:structural genomics, unknown function Chain: H: PDB Molecule:uncharacterized protein cgl0159; PDBTitle: crystal structure of cgl0159 from corynebacterium2 glutamicum (brevibacterium flavum). northeast structural3 genomics target cgr115 75 c1znnF_ not modelled 98.5 15 PDB header:biosynthetic protein Chain: F: PDB Molecule:plp synthase; PDBTitle: structure of the synthase subunit of plp synthase 76 d1vc4a_ not modelled 98.5 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Tryptophan biosynthesis enzymes 77 d1h5ya_ not modelled 98.4 11 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 78 c2htmB_ not modelled 98.3 17 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiazole biosynthesis protein thig; PDBTitle: crystal structure of ttha0676 from thermus thermophilus hb8 79 d1to3a_ not modelled 98.3 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 80 d1ka9f_ not modelled 98.3 16 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 81 c2y85D_ not modelled 98.3 14 PDB header:isomerase Chain: D: PDB Molecule:phosphoribosyl isomerase a; PDBTitle: crystal structure of mycobacterium tuberculosis phosphoribosyl2 isomerase with bound rcdrp 82 d1vzwa1 not modelled 98.0 14 Fold:TIM beta/alpha-barrel Superfamily:Ribulose-phoshate binding barrel Family:Histidine biosynthesis enzymes 83 d1xm3a_ not modelled 98.0 15 Fold:TIM beta/alpha-barrel Superfamily:ThiG-like Family:ThiG-like 84 c3nm3D_ not modelled 97.9 15 PDB header:transferase Chain: D: PDB Molecule:thiamine biosynthetic bifunctional enzyme; PDBTitle: the crystal structure of candida glabrata thi6, a bifunctional enzyme2 involved in thiamin biosyhthesis of eukaryotes 85 d1w0ma_ not modelled 97.9 15 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 86 c1piiA_ not modelled 97.8 13 PDB header:bifunctional(isomerase and synthase) Chain: A: PDB Molecule:n-(5'phosphoribosyl)anthranilate isomerase; PDBTitle: three-dimensional structure of the bifunctional enzyme2 phosphoribosylanthranilate isomerase:3 indoleglycerolphosphate synthase from escherichia coli4 refined at 2.0 angstroms resolution 87 d1hg3a_ not modelled 97.7 15 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 88 c2h6rG_ not modelled 97.7 15 PDB header:isomerase Chain: G: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase (tim) from2 methanocaldococcus jannaschii 89 d1vhna_ not modelled 97.5 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 90 c2d69B_ not modelled 97.5 16 PDB header:lyase Chain: B: PDB Molecule:ribulose bisphosphate carboxylase; PDBTitle: crystal structure of the complex of sulfate ion and octameric2 ribulose-1,5-bisphosphate carboxylase/oxygenase (rubisco) from3 pyrococcus horikoshii ot3 (form-2 crystal) 91 d2d69a1 not modelled 97.4 16 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 92 c3jrkG_ not modelled 97.3 13 PDB header:lyase Chain: G: PDB Molecule:tagatose 1,6-diphosphate aldolase 2; PDBTitle: a putative tagatose 1,6-diphosphate aldolase from streptococcus2 pyogenes 93 c1bwvA_ not modelled 97.2 11 PDB header:lyase Chain: A: PDB Molecule:protein (ribulose bisphosphate carboxylase); PDBTitle: activated ribulose 1,5-bisphosphate carboxylase/oxygenase (rubisco)2 complexed with the reaction intermediate analogue 2-carboxyarabinitol3 1,5-bisphosphate 94 c3ceuA_ not modelled 97.0 9 PDB header:transferase Chain: A: PDB Molecule:thiamine phosphate pyrophosphorylase; PDBTitle: crystal structure of thiamine phosphate pyrophosphorylase2 (bt_0647) from bacteroides thetaiotaomicron. northeast3 structural genomics consortium target btr268 95 d1o4ua1 not modelled 97.0 19 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 96 c2zbtB_ not modelled 97.0 14 PDB header:lyase Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: crystal structure of pyridoxine biosynthesis protein from thermus2 thermophilus hb8 97 d1svda1 not modelled 97.0 13 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 98 c1qpoA_ not modelled 96.8 16 PDB header:transferase Chain: A: PDB Molecule:quinolinate acid phosphoribosyl transferase; PDBTitle: quinolinate phosphoribosyl transferase (qaprtase) apo-enzyme from2 mycobacterium tuberculosis 99 c2oemA_ not modelled 96.8 15 PDB header:isomerase Chain: A: PDB Molecule:2,3-diketo-5-methylthiopentyl-1-phosphate enolase; PDBTitle: crystal structure of a rubisco-like protein from geobacillus2 kaustophilus liganded with mg2+ and 2,3-diketohexane 1-phosphate 100 d1bxna1 not modelled 96.8 13 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 101 c3ivuB_ not modelled 96.8 15 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 102 c1qapA_ not modelled 96.8 17 PDB header:glycosyltransferase Chain: A: PDB Molecule:quinolinic acid phosphoribosyltransferase; PDBTitle: quinolinic acid phosphoribosyltransferase with bound2 quinolinic acid 103 d1qpoa1 not modelled 96.8 19 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 104 d8ruca1 not modelled 96.6 15 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 105 d1qapa1 not modelled 96.5 16 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:NadC C-terminal domain-like 106 c1rldB_ not modelled 96.5 14 PDB header:lyase(carbon-carbon) Chain: B: PDB Molecule:ribulose 1,5 bisphosphate carboxylase/oxygenase (large PDBTitle: solid-state phase transition in the crystal structure of ribulose 1,5-2 biphosphate carboxylase(slash)oxygenase 107 d1bwva1 not modelled 96.5 13 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 108 c1rcxH_ not modelled 96.5 14 PDB header:lyase (carbon-carbon) Chain: H: PDB Molecule:ribulose bisphosphate carboxylase/oxygenase; PDBTitle: non-activated spinach rubisco in complex with its substrate2 ribulose-1,5-bisphosphate 109 d1gk8a1 not modelled 96.4 13 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 110 c1telA_ not modelled 96.4 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:ribulose bisphosphate carboxylase, large subunit; PDBTitle: crystal structure of a rubisco-like protein from chlorobium2 tepidum 111 c2nv2U_ not modelled 96.4 15 PDB header:lyase/transferase Chain: U: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: structure of the plp synthase complex pdx1/2 (yaad/e) from bacillus2 subtilis 112 c2yzrB_ not modelled 96.3 28 PDB header:lyase Chain: B: PDB Molecule:pyridoxal biosynthesis lyase pdxs; PDBTitle: crystal structure of pyridoxine biosynthesis protein from2 methanocaldococcus jannaschii 113 d1ej7l1 not modelled 96.3 14 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 114 d2f6ua1 not modelled 96.3 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 115 c3femB_ not modelled 96.3 13 PDB header:biosynthetic protein, transferase Chain: B: PDB Molecule:pyridoxine biosynthesis protein snz1; PDBTitle: structure of the synthase subunit pdx1.1 (snz1) of plp synthase from2 saccharomyces cerevisiae 116 c3fk4A_ not modelled 96.2 9 PDB header:isomerase Chain: A: PDB Molecule:rubisco-like protein; PDBTitle: crystal structure of rubisco-like protein from bacillus2 cereus atcc 14579 117 c3ffsC_ not modelled 96.1 19 PDB header:oxidoreductase Chain: C: PDB Molecule:inosine-5-monophosphate dehydrogenase; PDBTitle: the crystal structure of cryptosporidium parvum inosine-5'-2 monophosphate dehydrogenase 118 c2qygC_ not modelled 96.0 16 PDB header:unknown function Chain: C: PDB Molecule:ribulose bisphosphate carboxylase-like protein 2; PDBTitle: crystal structure of a rubisco-like protein rlp2 from rhodopseudomonas2 palustris 119 d1ykwa1 not modelled 95.9 16 Fold:TIM beta/alpha-barrel Superfamily:RuBisCo, C-terminal domain Family:RuBisCo, large subunit, C-terminal domain 120 c1o4uA_ not modelled 95.8 18 PDB header:transferase Chain: A: PDB Molecule:type ii quinolic acid phosphoribosyltransferase; PDBTitle: crystal structure of a nicotinate nucleotide pyrophosphorylase2 (tm1645) from thermotoga maritima at 2.50 a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0