Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	E	Q	H	A	Q	G	A	D	A	V	V	D	L	N	N	E	L	K	T	R	R	E	K	L	A	N	L	R	E	Q	G	I	A	F	P	N	D	F	R	R	D	H	T	S	D	Q	L	H	A	E	F	D	G	K	E	N	E	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?																		?																								?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	E	A	L	N	I	E	V	A	V	A	G	R	M	M	T	R	R	I	M	G	K	A	S	F	V	T	L	Q	D	V	G	G	R	I	Q	L	Y	V	A	R	D	D	L	P	E	G	V	Y	N	E	Q	F	K	K	W	D	L	G	D
Secondary structure
SS confidence
Disorder			?	?	?													?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	L	G	A	K	G	K	L	F	K	T	K	T	G	E	L	S	I	H	C	T	E	L	R	L	L	T	K	A	L	R	P	L	P	D	K	F	H	G	L	Q	D	Q	E	A	R	Y	R	Q	R	Y	L	D	L	I	S	N	D	E	S
Secondary structure
SS confidence
Disorder												?	?	?																							?			?	?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	N	T	F	K	V	R	S	Q	I	L	S	G	I	R	Q	F	M	V	N	R	G	F	M	E	V	E	T	P	M	M	Q	V	I	P	G	G	A	A	A	R	P	F	I	T	H	H	N	A	L	D	L	D	M	Y	L	R	I	A	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		E	L	Y	L	K	R	L	V	V	G	G	F	E	R	V	F	E	I	N	R	N	F	R	N	E	G	I	S	V	R	H	N	P	E	F	T	M	M	E	L	Y	M	A	Y	A	D	Y	K	D	L	I	E	L	T	E	S	L	F	R	T
Secondary structure
SS confidence
Disorder																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	A	Q	D	I	L	G	K	T	E	V	T	Y	G	D	V	T	L	D	F	G	K	P	F	E	K	L	T	M	R	E	A	I	K	K	Y	R	P	E	T	D	M	A	D	L	D	N	F	D	S	A	K	A	I	A	E	S	I	G	I
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		H	V	E	K	S	W	G	L	G	R	I	V	T	E	I	F	E	E	V	A	E	A	H	L	I	Q	P	T	F	I	T	E	Y	P	A	E	V	S	P	L	A	R	R	N	D	V	N	P	E	I	T	D	R	F	E	F	F	I	G	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	E	I	G	N	G	F	S	E	L	N	D	A	E	D	Q	A	Q	R	F	L	D	Q	V	A	A	K	D	A	G	D	D	E	A	M	F	Y	D	E	D	Y	V	T	A	L	E	H	G	L	P	P	T	A	G	L	G	I	G	I	D
Secondary structure
SS confidence
Disorder																													?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.
Sequence		R	M	V	M	L	F	T	N	S	H	T	I	R	D	V	I	L	F	P	A	M	R	P	V	K
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1e22 chain A Region: 12 - 503 Aligned: 485 Modelled: 492 Confidence: 100.0% Identity: 89% PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp Phyre2 PDB 3bju chain B Region: 14 - 502 Aligned: 480 Modelled: 489 Confidence: 100.0% Identity: 44% PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase Phyre2 PDB 3e9h chain B Region: 14 - 502 Aligned: 482 Modelled: 489 Confidence: 100.0% Identity: 55% PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine Phyre2 PDB 1b8a chain B Region: 41 - 502 Aligned: 421 Modelled: 443 Confidence: 100.0% Identity: 24% PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase Phyre2 PDB 1eqr chain C Region: 42 - 500 Aligned: 428 Modelled: 447 Confidence: 100.0% Identity: 28% PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli Phyre2 PDB 1efw chain A Region: 40 - 505 Aligned: 436 Modelled: 466 Confidence: 100.0% Identity: 27% PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli Phyre2 PDB 1wyd chain B Region: 41 - 502 Aligned: 414 Modelled: 443 Confidence: 100.0% Identity: 26% PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii Phyre2 PDB 1asy chain A Region: 41 - 500 Aligned: 430 Modelled: 441 Confidence: 100.0% Identity: 24% PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp Phyre2 PDB 2xgt chain B Region: 62 - 502 Aligned: 408 Modelled: 416 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate Phyre2 PDB 1x55 chain A Region: 42 - 502 Aligned: 415 Modelled: 442 Confidence: 100.0% Identity: 26% PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue Phyre2 PDB 3i7f chain A Region: 32 - 500 Aligned: 442 Modelled: 450 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica Phyre2 PDB 3m4q chain A Region: 61 - 502 Aligned: 398 Modelled: 424 Confidence: 100.0% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) Phyre2 PDB 1n9w chain A Region: 61 - 499 Aligned: 342 Modelled: 391 Confidence: 100.0% Identity: 28% PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus Phyre2 PDB 1l0w chain A domain 3 Region: 152 - 503 Aligned: 321 Modelled: 338 Confidence: 100.0% Identity: 28% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1c0a chain A domain 3 Region: 153 - 503 Aligned: 318 Modelled: 334 Confidence: 100.0% Identity: 28% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1eov chain A domain 2 Region: 159 - 503 Aligned: 317 Modelled: 326 Confidence: 100.0% Identity: 25% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1b8a chain A domain 2 Region: 152 - 503 Aligned: 322 Modelled: 333 Confidence: 100.0% Identity: 25% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1e1o chain A domain 2 Region: 162 - 503 Aligned: 341 Modelled: 342 Confidence: 100.0% Identity: 91% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1bbu chain A domain 2 Region: 162 - 503 Aligned: 342 Modelled: 342 Confidence: 100.0% Identity: 100% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1n9w chain A domain 2 Region: 169 - 499 Aligned: 259 Modelled: 283 Confidence: 100.0% Identity: 28% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 1 c1e22A_ 2 c3bjuB_ 3 c3e9hB_ 4 c1b8aB_ 5 c1eqrC_ 6 c1efwA_ 7 c1wydB_ 8 c1asyA_ 9 c2xgtB_ 10 c1x55A_ 11 c3i7fA_ 12 c3m4qA_ 13 c1n9wA_ 14 d1l0wa3 15 d1c0aa3 16 d1eova2 17 d1b8aa2 18 d1e1oa2 19 d1bbua2 20 d1n9wa2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1e22A_ 100.0 89 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp 2 c3bjuB_ 100.0 44 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase 3 c3e9hB_ 100.0 55 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine 4 c1b8aB_ 100.0 24 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 5 c1eqrC_ 100.0 28 PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli 6 c1efwA_ 100.0 27 PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli 7 c1wydB_ 100.0 26 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 8 c1asyA_ 100.0 24 PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp 9 c2xgtB_ 100.0 19 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 10 c1x55A_ 100.0 26 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 11 c3i7fA_ 100.0 22 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 12 c3m4qA_ 100.0 21 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) 13 c1n9wA_ 100.0 28 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 14 d1l0wa3 100.0 28 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 15 d1c0aa3 100.0 28 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 16 d1eova2 100.0 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 17 d1b8aa2 100.0 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 18 d1e1oa2 100.0 91 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 19 d1bbua2 100.0 100 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 20 d1n9wa2 100.0 28 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 21 d1nnha_ not modelled 100.0 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 22 c3g1zB_ not modelled 100.0 32 PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium 23 d1e1oa1 not modelled 100.0 85 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 24 d1bbua1 not modelled 100.0 100 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 25 c2znjB_ not modelled 100.0 22 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense 26 c2zimA_ not modelled 100.0 21 PDB header:ligase Chain: A: PDB Molecule:pyrrolysyl-trna synthetase; PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate 27 d1kmma2 not modelled 100.0 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 28 d1h4vb2 not modelled 100.0 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 29 c1z7nB_ not modelled 100.0 14 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 30 c2rhqA_ not modelled 100.0 18 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 31 d1krta_ not modelled 99.9 100 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 32 d1qe0a2 not modelled 99.9 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 33 d1wu7a2 not modelled 99.9 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 34 c3racA_ not modelled 99.9 12 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 35 d1jjca_ not modelled 99.9 25 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 36 c1b70A_ not modelled 99.9 27 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine 37 d1l0wa1 not modelled 99.9 25 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 38 d1c0aa1 not modelled 99.9 21 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 39 d1b8aa1 not modelled 99.9 21 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 40 c3pcoC_ not modelled 99.9 21 PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 41 d1n9wa1 not modelled 99.9 28 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 42 d1eova1 not modelled 99.8 22 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Anticodon-binding domain 43 c3l4gI_ not modelled 99.7 31 PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 44 c2du4B_ not modelled 99.6 21 PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys 45 c1adyA_ not modelled 99.5 14 PDB header:trna synthetase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate 46 c2du7C_ not modelled 99.5 24 PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase 47 c3cmqA_ not modelled 99.4 27 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial; PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase 48 c3od1A_ not modelled 99.3 15 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c 49 d1z7ma1 not modelled 99.3 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 50 c1wu7A_ not modelled 99.2 12 PDB header:ligase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum 51 d1nyra4 not modelled 99.2 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 52 c2i4lC_ not modelled 99.2 15 PDB header:ligase Chain: C: PDB Molecule:proline-trna ligase; PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase 53 c1nyqA_ not modelled 99.2 16 PDB header:ligase Chain: A: PDB Molecule:threonyl-trna synthetase 1; PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate 54 c3a32A_ not modelled 99.1 15 PDB header:ligase Chain: A: PDB Molecule:probable threonyl-trna synthetase 1; PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix 55 d1hc7a2 not modelled 99.1 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 56 c2j3mA_ not modelled 99.1 17 PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol 57 c2el9B_ not modelled 99.1 14 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue 58 d12asa_ not modelled 99.1 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 59 c1wleB_ not modelled 99.1 20 PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate 60 d1qf6a4 not modelled 99.1 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 61 c1fyfB_ not modelled 99.1 16 PDB header:ligase Chain: B: PDB Molecule:threonyl-trna synthetase; PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog 62 c3hriF_ not modelled 99.1 14 PDB header:ligase Chain: F: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei 63 c3mf2B_ not modelled 99.0 20 PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp 64 c1h4tD_ not modelled 99.0 13 PDB header:aminoacyl-trna synthetase Chain: D: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline 65 d1nj8a3 not modelled 98.9 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 66 c1qf6A_ not modelled 98.9 13 PDB header:ligase/rna Chain: A: PDB Molecule:threonyl-trna synthetase; PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna 67 c3ialB_ not modelled 98.9 14 PDB header:ligase Chain: B: PDB Molecule:prolyl-trna synthetase; PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate 68 c1ggmB_ not modelled 98.9 13 PDB header:ligase Chain: B: PDB Molecule:protein (glycyl-trna synthetase); PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate 69 c1atiA_ not modelled 98.9 16 PDB header:protein biosynthesis Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus 70 c1nj8C_ not modelled 98.8 19 PDB header:ligase Chain: C: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii 71 c3lssA_ not modelled 98.8 15 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 72 d1nj1a3 not modelled 98.8 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 73 c3netB_ not modelled 98.8 15 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120 74 d1atia2 not modelled 98.8 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 75 c1nj2A_ not modelled 98.7 20 PDB header:ligase Chain: A: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus 76 d1seta2 not modelled 98.7 24 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 77 c2dq0A_ not modelled 98.6 17 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 78 c2dq3A_ not modelled 98.6 17 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 79 c1sryB_ not modelled 98.6 23 PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution 80 d1b76a2 not modelled 98.6 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 81 c1qe0B_ not modelled 98.5 14 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase 82 c3qo8A_ not modelled 98.4 16 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 83 c3errB_ not modelled 98.4 23 PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase 84 c2cj9A_ not modelled 98.2 14 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate 85 c3kf6A_ not modelled 98.0 14 PDB header:structural protein Chain: A: PDB Molecule:protein stn1; PDBTitle: crystal structure of s. pombe stn1-ten1 complex 86 d1j5wa_ not modelled 98.0 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 87 d1usya_ not modelled 97.9 10 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 88 c2pmfA_ not modelled 97.8 24 PDB header:ligase Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant 89 c3e0eA_ not modelled 97.8 21 PDB header:replication Chain: A: PDB Molecule:replication protein a; PDBTitle: crystal structure of a domain of replication protein a from2 methanococcus maripaludis. northeast structural genomics3 targe mrr110b 90 c3ikmC_ not modelled 97.7 17 PDB header:transferase Chain: C: PDB Molecule:dna polymerase subunit gamma-2; PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme 91 d1g5ha2 not modelled 97.7 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 92 c1g5hA_ not modelled 97.5 17 PDB header:dna binding protein Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit; PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma 93 c3icaB_ not modelled 97.4 12 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of the beta subunit of a phenylalanyl-trna2 synthetase from porphyromonas gingivalis w83 94 c3dm3A_ not modelled 97.4 18 PDB header:replication Chain: A: PDB Molecule:replication factor a; PDBTitle: crystal structure of a domain of a replication factor a2 protein, from methanocaldococcus jannaschii. northeast3 structural genomics target mjr118e 95 c3ig2B_ not modelled 97.2 10 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of a putative phenylalanyl-trna synthetase2 (phers) beta chain domain from bacteroides fragilis to 2.1a 96 c3l4gL_ not modelled 97.1 13 PDB header:ligase Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 97 d2pi2a1 not modelled 96.9 13 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 98 c3kf8C_ not modelled 96.8 15 PDB header:structural protein Chain: C: PDB Molecule:protein stn1; PDBTitle: crystal structure of c. tropicalis stn1-ten1 complex 99 d1jjcb5 not modelled 96.7 23 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 100 d1gm5a2 not modelled 96.5 21 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:RecG "wedge" domain 101 c2k50A_ not modelled 96.5 24 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:replication factor a related protein; PDBTitle: solution nmr structure of the replication factor a related2 protein from methanobacterium thermoautotrophicum.3 northeast structural genomics target tr91a. 102 c2pi2A_ not modelled 96.0 13 PDB header:replication, dna binding protein Chain: A: PDB Molecule:replication protein a 32 kda subunit; PDBTitle: full-length replication protein a subunits rpa14 and rpa32 103 c3pcoD_ not modelled 95.6 19 PDB header:ligase Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 104 c2k75A_ not modelled 95.3 15 PDB header:dna binding protein Chain: A: PDB Molecule:uncharacterized protein ta0387; PDBTitle: solution nmr structure of the ob domain of ta0387 from2 thermoplasma acidophilum. northeast structural genomics3 consortium target tar80b. 105 c1yfsB_ not modelled 95.2 18 PDB header:ligase Chain: B: PDB Molecule:alanyl-trna synthetase; PDBTitle: the crystal structure of alanyl-trna synthetase in complex2 with l-alanine 106 c1ynxA_ not modelled 95.0 12 PDB header:dna binding protein Chain: A: PDB Molecule:replication factor-a protein 1; PDBTitle: solution structure of dna binding domain a (dbd-a) of2 s.cerevisiae replication protein a (rpa) 107 d2g4ca2 not modelled 95.0 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 108 d1jmca1 not modelled 94.1 16 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 109 c1gm5A_ not modelled 93.6 21 PDB header:helicase Chain: A: PDB Molecule:recg; PDBTitle: structure of recg bound to three-way dna junction 110 c1fguA_ not modelled 93.0 18 PDB header:replication Chain: A: PDB Molecule:replication protein a 70 kda dna-binding subunit; PDBTitle: ssdna-binding domain of the large subunit of replication2 protein a 111 d1nnxa_ not modelled 92.8 17 Fold:OB-fold Superfamily:Hypothetical protein YgiW Family:Hypothetical protein YgiW 112 d1o7ia_ not modelled 90.9 16 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 113 c3rf1B_ not modelled 90.9 16 PDB header:ligase Chain: B: PDB Molecule:glycyl-trna synthetase alpha subunit; PDBTitle: the crystal structure of glycyl-trna synthetase subunit alpha from2 campylobacter jejuni subsp. jejuni nctc 11168 114 c2rhsB_ not modelled 90.7 18 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 115 c2kenA_ not modelled 90.2 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved protein; PDBTitle: solution nmr structure of the ob domain (residues 67-166)2 of mm0293 from methanosarcina mazei. northeast structural3 genomics consortium target mar214a. 116 c2pqaB_ not modelled 88.7 18 PDB header:replication Chain: B: PDB Molecule:replication protein a 14 kda subunit; PDBTitle: crystal structure of full-length human rpa 14/32 heterodimer 117 c2ztgA_ not modelled 86.6 35 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa 118 c2akwB_ not modelled 86.5 24 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine 119 c2zzfA_ not modelled 86.2 29 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of alanyl-trna synthetase without2 oligomerization domain 120 c3hxxA_ not modelled 85.7 22 PDB header:ligase Chain: A: PDB Molecule:alanyl-trna synthetase; PDBTitle: crystal structure of catalytic fragment of e. coli alars in complex2 with amppcp

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0