Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76639
DateThu Jan 5 12:25:10 GMT 2012
Unique Job ID54e7285a0e32ba83

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3ly8A_
Top template information
PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
Confidence and coverage
Confidence:100.0% Coverage: 64%
294 residues ( 64% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
430 residues ( 94%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MDLENKFSYHFLEGLTLTEDGILTQGNEQVYIPQKELGVLIVLLESAGHVVLKDMIIESV
Secondary structure 
SS confidence 
Disorder  ???????
?
?
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  WKNIIVSDESLTRCIYSLRCIFEKIGYDRCIETIYRKGYRFSGQVFKTKINEDNTSDYSI
Secondary structure 
SS confidence 
Disorder 
?
??
?
??????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  AIFPFTTSLNTLDPLILNQELVQIISNKKIDGLYTYPMAATNFCNDHISQNSFLSRFKPD
Secondary structure 
SS confidence 
Disorder 
??????
??
?
??????????
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  YFVTGRINQNNAVNTLYIELIDAKNLFLIASNHLPVDELHNTSQFIIDNILQTVHKPERS
Secondary structure 
SS confidence 
Disorder 
??
??????
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  VRLAKQDQGYKNHYLSDEMLAGKKELYDFTPESIYRAMTIFDRLQNKSDIQTLKTECYCL
Secondary structure 
SS confidence 
Disorder  ??????????
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  LAECHMSLALHGKSELELAAQKALELLDYVSDITTVDGKILAIMGLITGLSGQAKVSHIL
Secondary structure 
SS confidence 
Disorder 
?
??
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  FEQAKIHSTDIASLYYYRALVHFHNEKIEEARICIDKSLQLEPRRRKAVVIKECVDMYVP
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........430.........440.........450........
Sequence  NPLKNNIKLYYKETESESHRVIIDNILKLKQLTRICMR
Secondary structure 
SS confidence 
Disorder 
????????
???
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3ly8 chain A

3D model

Region: 126 - 434
Aligned: 294
Modelled: 304
Confidence: 100.0%
Identity: 11%
PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc

Phyre2

PDB 3pe3 chain D

3D model

Region: 291 - 454
Aligned: 154
Modelled: 164
Confidence: 99.9%
Identity: 11%
PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate

Phyre2

PDB 2hqn chain A

3D model

Region: 4 - 110
Aligned: 107
Modelled: 107
Confidence: 99.9%
Identity: 18%
PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism

Phyre2

PDB 2jzy chain A

3D model

Region: 6 - 106
Aligned: 101
Modelled: 101
Confidence: 99.9%
Identity: 16%
PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein pcor;
PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae

Phyre2

PDB 1p2f chain A domain 1

3D model

Region: 9 - 103
Aligned: 94
Modelled: 95
Confidence: 99.9%
Identity: 29%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2

PDB 1gxq chain A

3D model

Region: 3 - 102
Aligned: 100
Modelled: 100
Confidence: 99.9%
Identity: 23%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2

PDB 2pmu chain D

3D model

Region: 8 - 104
Aligned: 95
Modelled: 97
Confidence: 99.9%
Identity: 19%
PDB header:transcription regulation
Chain: D: PDB Molecule:response regulator phop;
PDBTitle: crystal structure of the dna-binding domain of phop

Phyre2

PDB 2hwv chain A

3D model

Region: 7 - 104
Aligned: 98
Modelled: 98
Confidence: 99.9%
Identity: 14%
PDB header:transcription
Chain: A: PDB Molecule:dna-binding response regulator vicr;
PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily.

Phyre2

PDB 3q9v chain B

3D model

Region: 6 - 103
Aligned: 98
Modelled: 98
Confidence: 99.9%
Identity: 17%
PDB header:dna binding protein
Chain: B: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra c-terminal domain(123-221) from deinococcus2 radiodurans

Phyre2

PDB 1ys7 chain A domain 1

3D model

Region: 4 - 101
Aligned: 96
Modelled: 98
Confidence: 99.9%
Identity: 18%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2

PDB 1opc chain A

3D model

Region: 9 - 104
Aligned: 96
Modelled: 96
Confidence: 99.8%
Identity: 19%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2

PDB 2xpi chain A

3D model

Region: 209 - 449
Aligned: 225
Modelled: 241
Confidence: 99.8%
Identity: 11%
PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1

Phyre2

PDB 2zxj chain B

3D model

Region: 7 - 102
Aligned: 96
Modelled: 96
Confidence: 99.8%
Identity: 16%
PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulatory protein walr;
PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus

Phyre2

PDB 1d8d chain A

3D model

Region: 259 - 448
Aligned: 174
Modelled: 190
Confidence: 99.8%
Identity: 9%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 2k4j chain A

3D model

Region: 4 - 102
Aligned: 99
Modelled: 99
Confidence: 99.8%
Identity: 18%
PDB header:transcription
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: arsr dna binding domain

Phyre2

PDB 1kgs chain A domain 1

3D model

Region: 4 - 104
Aligned: 97
Modelled: 101
Confidence: 99.8%
Identity: 22%
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: C-terminal effector domain of the bipartite response regulators
Family: PhoB-like

Phyre2

PDB 2h6f chain A domain 1

3D model

Region: 271 - 448
Aligned: 166
Modelled: 178
Confidence: 99.8%
Identity: 10%
Fold: alpha-alpha superhelix
Superfamily: Protein prenylyltransferase
Family: Protein prenylyltransferase

Phyre2

PDB 1tno chain I

3D model

Region: 259 - 448
Aligned: 174
Modelled: 187
Confidence: 99.8%
Identity: 9%
PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b

Phyre2

PDB 2y4t chain A

3D model

Region: 253 - 454
Aligned: 186
Modelled: 202
Confidence: 99.8%
Identity: 27%
PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)

Phyre2

PDB 2oqr chain A

3D model

Region: 1 - 102
Aligned: 102
Modelled: 102
Confidence: 99.8%
Identity: 18%
PDB header:transcription,signaling protein
Chain: A: PDB Molecule:sensory transduction protein regx3;
PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis

Phyre2

PDB 2e2e chain A

3D model

Region: 321 - 458
Aligned: 137
Modelled: 137
Confidence: 99.7%
Identity: 19%
PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7

Phyre2
1
c3ly8A_
2
c3pe3D_
3
c2hqnA_
4
c2jzyA_
5
d1p2fa1
6
d1gxqa_
7
c2pmuD_
8
c2hwvA_
9
c3q9vB_
10
d1ys7a1
11
d1opca_
12
c2xpiA_
13
c2zxjB_
14
d1d8da_
15
c2k4jA_
16
d1kgsa1
17
d2h6fa1
18
c1tnoI_
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c2y4tA_
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c2oqrA_
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c2e2eA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3ly8A_
100.0 11 PDB header:signaling protein
Chain: A: PDB Molecule:transcriptional activator cadc;
PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc
2c3pe3D_
99.9 11 PDB header:transferase
Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n-
PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate
3c2hqnA_
99.9 18 PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism
4c2jzyA_
99.9 16 PDB header:transcription
Chain: A: PDB Molecule:transcriptional regulatory protein pcor;
PDBTitle: solution structure of c-terminal effector domain of2 putative two-component-system response regulator involved3 in copper resistance from klebsiella pneumoniae
5d1p2fa1
99.9 29 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
6d1gxqa_
99.9 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
7c2pmuD_
99.9 19 PDB header:transcription regulation
Chain: D: PDB Molecule:response regulator phop;
PDBTitle: crystal structure of the dna-binding domain of phop
8c2hwvA_
99.9 14 PDB header:transcription
Chain: A: PDB Molecule:dna-binding response regulator vicr;
PDBTitle: crystal structure of an essential response regulator dna binding2 domain, vicrc in enterococcus faecalis, a member of the yycf3 subfamily.
9c3q9vB_
99.9 17 PDB header:dna binding protein
Chain: B: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra c-terminal domain(123-221) from deinococcus2 radiodurans
10d1ys7a1
99.9 18 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
11d1opca_
99.8 19 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
12c2xpiA_
99.8 11 PDB header:cell cycle
Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9;
PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1
13c2zxjB_
99.8 16 PDB header:transcription
Chain: B: PDB Molecule:transcriptional regulatory protein walr;
PDBTitle: crystal structure of yycf dna-binding domain from staphylococcus2 aureus
14d1d8da_
99.8 9 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
15c2k4jA_
99.8 18 PDB header:transcription
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: arsr dna binding domain
16d1kgsa1
99.8 22 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
17d2h6fa1
99.8 10 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
18c1tnoI_
99.8 9 PDB header:transferase
Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit;
PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b
19c2y4tA_
99.8 27 PDB header:chaperone
Chain: A: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of the human co-chaperone p58(ipk)
20c2oqrA_
99.8 18 PDB header:transcription,signaling protein
Chain: A: PDB Molecule:sensory transduction protein regx3;
PDBTitle: the structure of the response regulator regx3 from mycobacterium2 tuberculosis
21c1ys7B_
not modelled 99.8 19 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulatory protein prra;
PDBTitle: crystal structure of the response regulator protein prra comlexed with2 mg2+
22d1dcea1
not modelled 99.7 8 Fold:alpha-alpha superhelix
Superfamily:Protein prenylyltransferase
Family:Protein prenylyltransferase
23c2hqrA_
not modelled 99.7 18 PDB header:signaling protein
Chain: A: PDB Molecule:putative transcriptional regulator;
PDBTitle: structure of a atypical orphan response regulator protein revealed a2 new phosphorylation-independent regulatory mechanism
24c3iegB_
not modelled 99.7 27 PDB header:chaperone
Chain: B: PDB Molecule:dnaj homolog subfamily c member 3;
PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a
25c3q75A_
not modelled 99.7 8 PDB header:transferase
Chain: A: PDB Molecule:farnesyltransferase alpha subunit;
PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide
26d1w3ba_
not modelled 99.7 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
27c1fchB_
not modelled 99.7 11 PDB header:signaling protein
Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor;
PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5
28c3as5A_
not modelled 99.7 11 PDB header:protein binding
Chain: A: PDB Molecule:mama;
PDBTitle: mama amb-1 p212121
29c3hymB_
not modelled 99.7 14 PDB header:cell cycle, ligase
Chain: B: PDB Molecule:cell division cycle protein 16 homolog;
PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure
30c2r5sB_
not modelled 99.7 15 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein vp0806;
PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633
31c1wao4_
not modelled 99.7 11 PDB header:hydrolase
Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5;
PDBTitle: pp5 structure
32c3fp4A_
not modelled 99.7 14 PDB header:transport protein
Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w;
PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment
33c3urzB_
not modelled 99.7 10 PDB header:protein binding
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution
34c2e2eA_
99.7 19 PDB header:lyase
Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit;
PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7
35c3gyzB_
not modelled 99.7 8 PDB header:chaperone
Chain: B: PDB Molecule:chaperone protein ipgc;
PDBTitle: crystal structure of ipgc from shigella flexneri
36d2c2la1
not modelled 99.7 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
37c2gwrA_
not modelled 99.7 19 PDB header:signaling protein
Chain: A: PDB Molecule:dna-binding response regulator mtra;
PDBTitle: crystal structure of the response regulator protein mtra from2 mycobacterium tuberculosis
38c2xcbA_
not modelled 99.7 7 PDB header:protein binding
Chain: A: PDB Molecule:regulatory protein pcrh;
PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd
39c2hyzA_
not modelled 99.7 16 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form)
40c3cvpA_
not modelled 99.7 16 PDB header:transport protein
Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5;
PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl)
41c2ho1B_
not modelled 99.7 12 PDB header:protein binding
Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf;
PDBTitle: functional characterization of pseudomonas aeruginosa pilf
42c2vq2A_
not modelled 99.7 9 PDB header:structural protein
Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching
PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor
43d1fcha_
not modelled 99.7 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
44d1zu2a1
not modelled 99.7 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
45c2q7fA_
not modelled 99.7 10 PDB header:protein binding
Chain: A: PDB Molecule:yrrb protein;
PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site
46d1hh8a_
not modelled 99.6 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
47c2vsnB_
not modelled 99.6 14 PDB header:transferase
Chain: B: PDB Molecule:xcogt;
PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation
48d1xnfa_
not modelled 99.6 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
49c2c2lD_
not modelled 99.6 15 PDB header:chaperone
Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein;
PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase
50c3sz7A_
not modelled 99.6 14 PDB header:chaperone regulator
Chain: A: PDB Molecule:hsc70 cochaperone (sgt);
PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus
51c3draA_
not modelled 99.6 6 PDB header:transferase
Chain: A: PDB Molecule:protein
PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp
52c1p2fA_
not modelled 99.6 29 PDB header:transcription
Chain: A: PDB Molecule:response regulator;
PDBTitle: crystal structure analysis of response regulator drrb, a2 thermotoga maritima ompr/phob homolog
53c2katA_
not modelled 99.6 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206
54d1elwa_
not modelled 99.6 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
55d2ff4a1
not modelled 99.6 23 Fold:DNA/RNA-binding 3-helical bundle
Superfamily:C-terminal effector domain of the bipartite response regulators
Family:PhoB-like
56c3mkrA_
not modelled 99.6 10 PDB header:transport protein
Chain: A: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat
57c2kckA_
not modelled 99.6 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tpr repeat;
PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a
58c3r0jA_
not modelled 99.6 19 PDB header:dna binding protein
Chain: A: PDB Molecule:possible two component system response transcriptional
PDBTitle: structure of phop from mycobacterium tuberculosis
59c2gw1A_
not modelled 99.6 9 PDB header:protein transport
Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor;
PDBTitle: crystal structure of the yeast tom70
60c3k9iA_
not modelled 99.6 10 PDB header:protein binding
Chain: A: PDB Molecule:bh0479 protein;
PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution
61d1a17a_
not modelled 99.6 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
62c3mv3B_
not modelled 99.6 12 PDB header:protein transport
Chain: B: PDB Molecule:coatomer subunit epsilon;
PDBTitle: crystal structure of a-cop in complex with e-cop
63c2vyiA_
not modelled 99.5 14 PDB header:chaperone
Chain: A: PDB Molecule:sgta protein;
PDBTitle: crystal structure of the tpr domain of human sgt
64c1ltxA_
not modelled 99.5 9 PDB header:transferase/protein binding
Chain: A: PDB Molecule:rab geranylgeranyltransferase alpha subunit;
PDBTitle: structure of rab escort protein-1 in complex with rab2 geranylgeranyl transferase and isoprenoid
65c2pl2A_
not modelled 99.5 18 PDB header:protein binding
Chain: A: PDB Molecule:hypothetical conserved protein ttc0263;
PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27
66d2hqsa2
not modelled 99.5 14 Fold:Anticodon-binding domain-like
Superfamily:TolB, N-terminal domain
Family:TolB, N-terminal domain
67d1elra_
not modelled 99.5 11 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
68c2vgxA_
not modelled 99.5 8 PDB header:chaperone
Chain: A: PDB Molecule:chaperone sycd;
PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd
69d1hxia_
not modelled 99.5 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
70c3q49B_
not modelled 99.5 16 PDB header:ligase/chaperone
Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1;
PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide
71d2buga1
not modelled 99.5 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
72d2ooea1
not modelled 99.5 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
73c1kgsA_
not modelled 99.4 23 PDB header:dna binding protein
Chain: A: PDB Molecule:dna binding response regulator d;
PDBTitle: crystal structure at 1.50 a of an ompr/phob homolog from thermotoga2 maritima
74c1na3A_
not modelled 99.4 14 PDB header:de novo protein
Chain: A: PDB Molecule:designed protein ctpr2;
PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif
75c2dbaA_
not modelled 99.4 15 PDB header:structural protein
Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform
PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2
76c3qdnA_
not modelled 99.4 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative thioredoxin protein;
PDBTitle: putative thioredoxin protein from salmonella typhimurium
77d1nzna_
not modelled 99.4 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
78d1iyga_
not modelled 99.4 14 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
79c1ihgA_
not modelled 99.4 11 PDB header:isomerase
Chain: A: PDB Molecule:cyclophilin 40;
PDBTitle: bovine cyclophilin 40, monoclinic form
80d1zbpa1
not modelled 99.4 11 Fold:ImpE-like
Superfamily:ImpE-like
Family:ImpE-like
81d1pc2a_
not modelled 99.4 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
82c1kt0A_
not modelled 99.4 16 PDB header:isomerase
Chain: A: PDB Molecule:51 kda fk506-binding protein;
PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes
83c2uy1A_
not modelled 99.4 12 PDB header:rna-binding protein
Chain: A: PDB Molecule:cleavage stimulation factor 77;
PDBTitle: crystal structure of cstf-77
84c3gw4B_
not modelled 99.4 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b.
85c2kcvA_
not modelled 99.4 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tetratricopeptide repeat domain protein;
PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c
86d1kt1a1
not modelled 99.4 12 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
87c2xevB_
not modelled 99.4 11 PDB header:metal binding
Chain: B: PDB Molecule:ybgf;
PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf
88d1p5qa1
not modelled 99.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
89c3rkvA_
not modelled 99.3 13 PDB header:isomerase
Chain: A: PDB Molecule:putative peptidylprolyl isomerase;
PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans
90d1ihga1
not modelled 99.3 13 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
91d1hz4a_
not modelled 99.3 15 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Transcription factor MalT domain III
92c2ff4B_
not modelled 99.3 20 PDB header:transcription
Chain: B: PDB Molecule:probable regulatory protein embr;
PDBTitle: mycobacterium tuberculosis embr in complex with low affinity2 phosphopeptide
93c2l6jA_
not modelled 99.3 8 PDB header:protein binding
Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90;
PDBTitle: tah1 complexed by meevd
94c3q15A_
not modelled 99.3 8 PDB header:hydrolase/kinase
Chain: A: PDB Molecule:response regulator aspartate phosphatase h;
PDBTitle: crystal structure of raph complexed with spo0f
95c1qz2B_
not modelled 99.3 15 PDB header:isomerase/chaperone
Chain: B: PDB Molecule:fk506-binding protein 4;
PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90
96d2hr2a1
not modelled 99.3 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:CT2138-like
97c2fbnA_
not modelled 99.3 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative;
PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain
98d2fbna1
not modelled 99.3 16 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
99d1qsaa1
not modelled 99.3 8 Fold:alpha-alpha superhelix
Superfamily:Bacterial muramidases
Family:Bacterial muramidases
100c2avpA_
not modelled 99.3 18 PDB header:de novo protein
Chain: A: PDB Molecule:synthetic consensus tpr protein;
PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix
101c2if4A_
not modelled 99.2 12 PDB header:signaling protein
Chain: A: PDB Molecule:atfkbp42;
PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana
102c2yhcA_
not modelled 99.2 13 PDB header:membrane protein
Chain: A: PDB Molecule:upf0169 lipoprotein yfio;
PDBTitle: structure of bamd from e. coli
103c2ifuA_
not modelled 99.2 13 PDB header:endocytosis/exocytosis
Chain: A: PDB Molecule:gamma-snap;
PDBTitle: crystal structure of a gamma-snap from danio rerio
104d2onda1
not modelled 99.2 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:HAT/Suf repeat
105d1y8ma1
not modelled 99.2 8 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
106c3q9sA_
not modelled 99.2 15 PDB header:dna binding protein
Chain: A: PDB Molecule:dna-binding response regulator;
PDBTitle: crystal structure of rra(1-215) from deinococcus radiodurans
107c3qkyA_
not modelled 99.1 13 PDB header:membrane protein
Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio;
PDBTitle: crystal structure of rhodothermus marinus bamd
108c2kc7A_
not modelled 99.1 11 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:bfr218_protein;
PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218
109c3ulqA_
not modelled 99.1 9 PDB header:gene regulation/transcription activator
Chain: A: PDB Molecule:response regulator aspartate phosphatase f;
PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain
110d1tjca_
not modelled 99.1 17 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
111d1qqea_
not modelled 99.0 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
112c3beeB_
not modelled 99.0 20 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative yfre protein;
PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus
113c3sf4B_
not modelled 98.9 18 PDB header:signaling protein/protein binding
Chain: B: PDB Molecule:g-protein-signaling modulator 2;
PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn
114c3fflC_
not modelled 98.9 17 PDB header:cell cycle
Chain: C: PDB Molecule:anaphase-promoting complex subunit 7;
PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7
115d2pqrb1
not modelled 98.8 9 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:Tetratricopeptide repeat (TPR)
116c3n71A_
not modelled 98.8 13 PDB header:transcription
Chain: A: PDB Molecule:histone lysine methyltransferase smyd1;
PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1
117d2ff4a2
not modelled 98.7 10 Fold:alpha-alpha superhelix
Superfamily:TPR-like
Family:BTAD-like
118c3nf1A_
not modelled 98.6 11 PDB header:motor protein, transport protein
Chain: A: PDB Molecule:kinesin light chain 1;
PDBTitle: crystal structure of the tpr domain of kinesin light chain 1
119c3q3hA_
not modelled 98.5 6 PDB header:transferase
Chain: A: PDB Molecule:hmw1c-like glycosyltransferase;
PDBTitle: crystal structure of the actinobacillus pleuropneumoniae hmw1c2 glycosyltransferase in complex with udp-glc
120c1slyA_
not modelled 98.4 8 PDB header:glycosyltransferase
Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase;
PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0