Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	N	P	T	V	I	K	L	Q	D	G	N	V	M	P	Q	L	G	L	G	V	W	Q	A	S	N	E	E	V	I	T	A	I	Q	K	A	L	E	V	G	Y	R	S	I	D	T	A	A	A	Y	K	N	E	E	G	V	G	K	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	K	N	A	S	V	N	R	E	E	L	F	I	T	T	K	L	W	N	D	D	H	K	R	P	R	E	A	L	L	D	S	L	K	K	L	Q	L	D	Y	I	D	L	Y	L	M	H	W	P	V	P	A	I	D	H	Y	V	E	A	W
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		K	G	M	I	E	L	Q	K	E	G	L	I	K	S	I	G	V	C	N	F	Q	I	H	H	L	Q	R	L	I	D	E	T	G	V	T	P	V	I	N	Q	I	E	L	H	P	L	M	Q	Q	R	Q	L	H	A	W	N	A	T	H	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	Q	T	E	S	W	S	P	L	A	Q	G	G	K	G	V	F	D	Q	K	V	I	R	D	L	A	D	K	Y	G	K	T	P	A	Q	I	V	I	R	W	H	L	D	S	G	L	V	V	I	P	K	S	V	T	P	S	R	I	A	E
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.
Sequence		N	F	D	V	W	D	F	R	L	D	K	D	E	L	G	E	I	A	K	L	D	Q	G	K	R	L	G	P	D	P	D	Q	F	G	G
Secondary structure
SS confidence
Disorder																							?		?							?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1mzr chain A Region: 2 - 275 Aligned: 274 Modelled: 274 Confidence: 100.0% Identity: 100% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1vbj chain B Region: 1 - 274 Aligned: 270 Modelled: 274 Confidence: 100.0% Identity: 42% PDB header:oxidoreductase Chain: B: PDB Molecule:prostaglandin f synthase; PDBTitle: the crystal structure of prostaglandin f synthase from2 trypanosoma brucei Phyre2 PDB 1frb chain A Region: 5 - 275 Aligned: 271 Modelled: 271 Confidence: 100.0% Identity: 41% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3f7j chain B Region: 2 - 272 Aligned: 267 Modelled: 271 Confidence: 100.0% Identity: 45% PDB header:oxidoreductase Chain: B: PDB Molecule:yvgn protein; PDBTitle: b.subtilis yvgn Phyre2 PDB 1hw6 chain A Region: 2 - 261 Aligned: 256 Modelled: 260 Confidence: 100.0% Identity: 51% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3h7u chain A Region: 2 - 275 Aligned: 273 Modelled: 274 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c9 Phyre2 PDB 1hqt chain A Region: 5 - 275 Aligned: 271 Modelled: 271 Confidence: 100.0% Identity: 38% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 2wzt chain A Region: 2 - 262 Aligned: 258 Modelled: 261 Confidence: 100.0% Identity: 42% PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of a mycobacterium aldo-keto reductase in2 its apo and liganded form Phyre2 PDB 3o0k chain B Region: 2 - 261 Aligned: 254 Modelled: 260 Confidence: 100.0% Identity: 51% PDB header:oxidoreductase Chain: B: PDB Molecule:aldo/keto reductase; PDBTitle: crystal structure of aldo/keto reductase from brucella melitensis Phyre2 PDB 1qwk chain A Region: 5 - 275 Aligned: 270 Modelled: 271 Confidence: 100.0% Identity: 39% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1vp5 chain A Region: 5 - 269 Aligned: 262 Modelled: 262 Confidence: 100.0% Identity: 45% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3b3d chain A Region: 2 - 274 Aligned: 269 Modelled: 273 Confidence: 100.0% Identity: 46% PDB header:oxidoreductase Chain: A: PDB Molecule:putative morphine dehydrogenase; PDBTitle: b.subtilis ytbe Phyre2 PDB 2bgs chain A Region: 5 - 273 Aligned: 269 Modelled: 269 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: A: PDB Molecule:aldose reductase; PDBTitle: holo aldose reductase from barley Phyre2 PDB 1q5m chain A Region: 3 - 275 Aligned: 273 Modelled: 273 Confidence: 100.0% Identity: 36% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1c9w chain A Region: 5 - 274 Aligned: 270 Modelled: 270 Confidence: 100.0% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1ah4 chain A Region: 5 - 275 Aligned: 271 Modelled: 271 Confidence: 100.0% Identity: 41% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 1mi3 chain A Region: 2 - 272 Aligned: 270 Modelled: 271 Confidence: 100.0% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 2alr chain A Region: 5 - 275 Aligned: 267 Modelled: 271 Confidence: 100.0% Identity: 40% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 PDB 3up8 chain B Region: 3 - 273 Aligned: 268 Modelled: 268 Confidence: 100.0% Identity: 28% PDB header:oxidoreductase Chain: B: PDB Molecule:putative 2,5-diketo-d-gluconic acid reductase b; PDBTitle: crystal structure of a putative 2,5-diketo-d-gluconic acid reductase b Phyre2 PDB 1afs chain A Region: 2 - 275 Aligned: 273 Modelled: 274 Confidence: 100.0% Identity: 34% Fold: TIM beta/alpha-barrel Superfamily: NAD(P)-linked oxidoreductase Family: Aldo-keto reductases (NADP) Phyre2 1 d1mzra_ 2 c1vbjB_ 3 d1frba_ 4 c3f7jB_ 5 d1hw6a_ 6 c3h7uA_ 7 d1hqta_ 8 c2wztA_ 9 c3o0kB_ 10 d1qwka_ 11 d1vp5a_ 12 c3b3dA_ 13 c2bgsA_ 14 d1q5ma_ 15 d1c9wa_ 16 d1ah4a_ 17 d1mi3a_ 18 d2alra_ 19 c3up8B_ 20 d1afsa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1mzra_ 100.0 100 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 2 c1vbjB_ 100.0 42 PDB header:oxidoreductase Chain: B: PDB Molecule:prostaglandin f synthase; PDBTitle: the crystal structure of prostaglandin f synthase from2 trypanosoma brucei 3 d1frba_ 100.0 41 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 4 c3f7jB_ 100.0 45 PDB header:oxidoreductase Chain: B: PDB Molecule:yvgn protein; PDBTitle: b.subtilis yvgn 5 d1hw6a_ 100.0 51 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 6 c3h7uA_ 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c9 7 d1hqta_ 100.0 38 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 8 c2wztA_ 100.0 42 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of a mycobacterium aldo-keto reductase in2 its apo and liganded form 9 c3o0kB_ 100.0 51 PDB header:oxidoreductase Chain: B: PDB Molecule:aldo/keto reductase; PDBTitle: crystal structure of aldo/keto reductase from brucella melitensis 10 d1qwka_ 100.0 39 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 11 d1vp5a_ 100.0 45 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 12 c3b3dA_ 100.0 46 PDB header:oxidoreductase Chain: A: PDB Molecule:putative morphine dehydrogenase; PDBTitle: b.subtilis ytbe 13 c2bgsA_ 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:aldose reductase; PDBTitle: holo aldose reductase from barley 14 d1q5ma_ 100.0 36 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 15 d1c9wa_ 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 16 d1ah4a_ 100.0 41 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 17 d1mi3a_ 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 18 d2alra_ 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 19 c3up8B_ 100.0 28 PDB header:oxidoreductase Chain: B: PDB Molecule:putative 2,5-diketo-d-gluconic acid reductase b; PDBTitle: crystal structure of a putative 2,5-diketo-d-gluconic acid reductase b 20 d1afsa_ 100.0 34 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 21 d1j96a_ not modelled 100.0 38 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 22 d1us0a_ not modelled 100.0 40 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 23 d1s1pa_ not modelled 100.0 37 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 24 c1zgdB_ not modelled 100.0 37 PDB header:plant protein Chain: B: PDB Molecule:chalcone reductase; PDBTitle: chalcone reductase complexed with nadp+ at 1.7 angstrom2 resolution 25 c3h7rA_ not modelled 100.0 38 PDB header:oxidoreductase Chain: A: PDB Molecule:aldo-keto reductase; PDBTitle: crystal structure of the plant stress-response enzyme akr4c8 26 c3buvB_ not modelled 100.0 35 PDB header:oxidoreductase Chain: B: PDB Molecule:3-oxo-5-beta-steroid 4-dehydrogenase; PDBTitle: crystal structure of human delta(4)-3-ketosteroid 5-beta-reductase in2 complex with nadp and hepes. resolution: 1.35 a. 27 d1ur3m_ not modelled 100.0 24 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 28 d1lqaa_ not modelled 100.0 29 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 29 c3n2tA_ not modelled 100.0 23 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the glycerol dehydrogenase akr11b4 from gluconobacter2 oxydans 30 c3krbB_ not modelled 100.0 37 PDB header:oxidoreductase Chain: B: PDB Molecule:aldose reductase; PDBTitle: structure of aldose reductase from giardia lamblia at 1.75a resolution 31 c3erpA_ not modelled 100.0 26 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of idp01002, a putative oxidoreductase from and essential2 gene of salmonella typhimurium 32 d1pz1a_ not modelled 100.0 27 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 33 d1pyfa_ not modelled 100.0 25 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 34 d3eaua1 not modelled 100.0 27 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 35 c3lutA_ not modelled 100.0 27 PDB header:membrane protein Chain: A: PDB Molecule:voltage-gated potassium channel subunit beta-2; PDBTitle: a structural model for the full-length shaker potassium channel kv1.2 36 c3n6qF_ not modelled 100.0 23 PDB header:oxidoreductase Chain: F: PDB Molecule:yghz aldo-keto reductase; PDBTitle: crystal structure of yghz from e. coli 37 c1ynpA_ not modelled 100.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: aldo-keto reductase akr11c1 from bacillus halodurans (apo form) 38 d1gvea_ not modelled 100.0 20 Fold:TIM beta/alpha-barrel Superfamily:NAD(P)-linked oxidoreductase Family:Aldo-keto reductases (NADP) 39 c2bp1C_ not modelled 100.0 19 PDB header:oxidoreductase Chain: C: PDB Molecule:aflatoxin b1 aldehyde reductase member 2; PDBTitle: structure of the aflatoxin aldehyde reductase in complex2 with nadph 40 c3ln3A_ not modelled 100.0 33 PDB header:oxidoreductase Chain: A: PDB Molecule:dihydrodiol dehydrogenase; PDBTitle: crystal structure of putative reductase (np_038806.2) from2 mus musculus at 1.18 a resolution 41 c3g8rA_ not modelled 74.8 13 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 42 c2ftpA_ not modelled 59.7 17 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 43 d1jpma1 not modelled 58.7 8 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 44 d1x87a_ not modelled 56.2 18 Fold:Urocanase Superfamily:Urocanase Family:Urocanase 45 c3oa3A_ not modelled 46.7 12 PDB header:lyase Chain: A: PDB Molecule:aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 coccidioides immitis 46 c3k13A_ not modelled 45.5 16 PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron 47 c1vliA_ not modelled 43.3 9 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 48 d1o0ya_ not modelled 40.7 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 49 c3eegB_ not modelled 39.4 14 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 50 d1ub3a_ not modelled 39.3 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 51 d1r0ma1 not modelled 36.9 14 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 52 c1xuzA_ not modelled 35.8 15 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 53 d1vlia2 not modelled 35.5 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 54 d1sr9a2 not modelled 34.4 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 55 d1mzha_ not modelled 34.2 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 56 c2yl8A_ not modelled 32.8 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 57 c3ngjC_ not modelled 32.7 7 PDB header:lyase Chain: C: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of a putative deoxyribose-phosphate aldolase from2 entamoeba histolytica 58 c3ewbX_ not modelled 31.7 12 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 59 c2ph5A_ not modelled 29.7 7 PDB header:transferase Chain: A: PDB Molecule:homospermidine synthase; PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54 60 c3ke8A_ not modelled 29.7 24 PDB header:oxidoreductase Chain: A: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate PDBTitle: crystal structure of isph:hmbpp-complex 61 c2cw6B_ not modelled 29.7 23 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 62 c2it0A_ not modelled 27.1 12 PDB header:transcription/dna Chain: A: PDB Molecule:iron-dependent repressor ider; PDBTitle: crystal structure of a two-domain ider-dna complex crystal2 form ii 63 c2ylaA_ not modelled 26.8 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 64 c2qdeA_ not modelled 26.7 11 PDB header:lyase Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing enzyme family PDBTitle: crystal structure of mandelate racemase/muconate lactonizing family2 protein from azoarcus sp. ebn1 65 d2ijqa1 not modelled 26.6 9 Fold:Hyaluronidase domain-like Superfamily:TTHA0068-like Family:TTHA0068-like 66 d1oi7a1 not modelled 25.3 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 67 c3dnfB_ not modelled 24.9 16 PDB header:oxidoreductase Chain: B: PDB Molecule:4-hydroxy-3-methylbut-2-enyl diphosphate reductase; PDBTitle: structure of (e)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase,2 the terminal enzyme of the non-mevalonate pathway 68 c3rpmA_ not modelled 24.6 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetyl-hexosaminidase; PDBTitle: crystal structure of the first gh20 domain of a novel beta-n-acetyl-2 hexosaminidase strh from streptococcus pneumoniae r6 69 d1wlza1 not modelled 24.4 4 Fold:EF Hand-like Superfamily:EF-hand Family:EF-hand modules in multidomain proteins 70 c1wlzD_ not modelled 24.4 4 PDB header:unknown function Chain: D: PDB Molecule:cap-binding protein complex interacting protein PDBTitle: crystal structure of djbp fragment which was obtained by2 limited proteolysis 71 c2x4hA_ not modelled 24.1 7 PDB header:transcription Chain: A: PDB Molecule:hypothetical protein sso2273; PDBTitle: crystal structure of the hypothetical protein sso2273 from2 sulfolobus solfataricus 72 d1vcva1 not modelled 23.9 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 73 d1n7ka_ not modelled 23.6 6 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 74 d1yhta1 not modelled 23.4 11 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 75 c1u83A_ not modelled 23.0 14 PDB header:lyase Chain: A: PDB Molecule:phosphosulfolactate synthase; PDBTitle: psl synthase from bacillus subtilis 76 d1u83a_ not modelled 23.0 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 77 c3ng3A_ not modelled 22.7 12 PDB header:lyase Chain: A: PDB Molecule:deoxyribose-phosphate aldolase; PDBTitle: crystal structure of deoxyribose phosphate aldolase from mycobacterium2 avium 104 in a schiff base with an unknown aldehyde 78 c2k6xA_ not modelled 22.0 4 PDB header:transcription Chain: A: PDB Molecule:rna polymerase sigma factor rpod; PDBTitle: autoregulation of a group 1 bacterial sigma factor involves2 the formation of a region 1.1- induced compacted structure 79 c3lmzA_ not modelled 21.8 10 PDB header:isomerase Chain: A: PDB Molecule:putative sugar isomerase; PDBTitle: crystal structure of putative sugar isomerase. (yp_001305105.1) from2 parabacteroides distasonis atcc 8503 at 1.44 a resolution 80 c2nqlB_ not modelled 21.5 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:isomerase/lactonizing enzyme; PDBTitle: crystal structure of a member of the enolase superfamily from2 agrobacterium tumefaciens 81 c2eeeA_ not modelled 21.0 32 PDB header:gene regulation Chain: A: PDB Molecule:uncharacterized protein c6orf130; PDBTitle: solution structure of the a1pp domain from human protein2 c6orf130 82 c3smaD_ not modelled 20.8 21 PDB header:transferase Chain: D: PDB Molecule:frbf; PDBTitle: a new n-acetyltransferase fold in the structure and mechanism of the2 phosphonate biosynthetic enzyme frbf 83 d1p1xa_ not modelled 19.9 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 84 d2zdra2 not modelled 19.5 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 85 c2zyfA_ not modelled 18.6 9 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 86 c3e4fB_ not modelled 18.4 23 PDB header:transferase Chain: B: PDB Molecule:aminoglycoside n3-acetyltransferase; PDBTitle: crystal structure of ba2930- a putative aminoglycoside n3-2 acetyltransferase from bacillus anthracis 87 d1sjda1 not modelled 17.9 16 Fold:TIM beta/alpha-barrel Superfamily:Enolase C-terminal domain-like Family:D-glucarate dehydratase-like 88 d1g3wa2 not modelled 17.2 10 Fold:Iron-dependent repressor protein, dimerization domain Superfamily:Iron-dependent repressor protein, dimerization domain Family:Iron-dependent repressor protein, dimerization domain 89 c3ejfA_ not modelled 17.2 32 PDB header:hydrolase Chain: A: PDB Molecule:non-structural protein 3; PDBTitle: crystal structure of ibv x-domain at ph 8.5 90 c1ydnA_ not modelled 16.7 20 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 91 c3ik4A_ not modelled 16.6 13 PDB header:isomerase Chain: A: PDB Molecule:mandelate racemase/muconate lactonizing protein; PDBTitle: crystal structure of mandelate racemase/muconate lactonizing protein2 from herpetosiphon aurantiacus 92 c3i6eA_ not modelled 16.5 11 PDB header:isomerase Chain: A: PDB Molecule:muconate cycloisomerase i; PDBTitle: crystal structure of muconate lactonizing enzyme from2 ruegeria pomeroyi. 93 d1sfla_ not modelled 16.4 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 94 c1nvmG_ not modelled 16.4 11 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 95 c3l2iB_ not modelled 15.3 14 PDB header:lyase Chain: B: PDB Molecule:3-dehydroquinate dehydratase; PDBTitle: 1.85 angstrom crystal structure of the 3-dehydroquinate dehydratase2 (arod) from salmonella typhimurium lt2. 96 c3ivuB_ not modelled 15.3 11 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 97 c3ktcB_ not modelled 14.9 35 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase; PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution 98 c3ddmD_ not modelled 14.8 10 PDB header:lyase Chain: D: PDB Molecule:putative mandelate racemase/muconate lactonizing PDBTitle: crystal structure of mandelate racemase/muconate2 lactonizing enzyme from bordetella bronchiseptica rb50 99 c2qgyA_ not modelled 14.7 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:enolase from the environmental genome shotgun PDBTitle: crystal structure of an enolase from the environmental2 genome shotgun sequencing of the sargasso sea

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0