Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	R	N	K	N	I	I	M	L	L	M	S	S	L	I	L	S	G	C	G	P	Q	P	E	N	K	E	S	Q	Q	Q	Q	P	S	T	P	T	E	Q	Q	V	L	A	A	Q	Q	A	A	I	K	E	A	E	Q	S	A	A	A	A	K
Secondary structure
SS confidence
Disorder		?	?	?														?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	A	Q	Q	E	V	Q	Q	Y	S	D	K	Q	A	L	Q	G	R	L	Q	E	A	P	T	F	A	R	A	A	K	A	K	A	T	H	I	A	N	P	G	T	A	R	Y	Q	Q	F	D	D	N	P	V	K	Q	V	A	Q	N	P
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?	?	?	?		?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	A	T	F	S	L	D	V	D	T	G	S	Y	A	N	V	R	R	F	L	N	Q	G	L	L	P	P	P	D	A	V	R	V	E	E	I	V	N	Y	F	P	S	D	W	D	I	K	D	K	Q	S	I	P	A	S	K	P	I	P	F
Secondary structure
SS confidence
Disorder																										?	?		?																		?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	M	R	Y	E	L	A	P	A	P	W	N	E	Q	R	T	L	L	K	V	D	I	L	A	K	D	R	K	S	E	E	L	P	A	S	N	L	V	F	L	I	D	T	S	G	S	M	I	S	D	E	R	L	P	L	I	Q	S	S	L
Secondary structure
SS confidence
Disorder									?	?														?	?	?	?	?	?	?	?	?	?																?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		K	L	L	V	K	E	L	R	E	Q	D	N	I	A	I	V	T	Y	A	G	D	S	R	I	A	L	P	S	I	S	G	S	H	K	A	E	I	N	A	A	I	D	S	L	D	A	E	G	S	T	N	G	G	A	G	L	E	L	A	Y
Secondary structure
SS confidence
Disorder																													?	?															?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Q	Q	A	T	K	G	F	I	K	G	G	I	N	R	I	L	L	A	T	D	G	D	F	N	V	G	I	D	D	P	K	S	I	E	S	M	V	K	K	Q	R	E	S	G	V	T	L	S	T	F	G	V	G	N	S	N	Y	N	E	A
Secondary structure
SS confidence
Disorder						?	?	?	?	?	?	?	?												?	?	?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		M	M	V	R	I	A	D	V	G	N	G	N	Y	S	Y	I	D	T	L	S	E	A	Q	K	V	L	N	S	E	M	R	Q	M	L	I	T	V	A	K	D	V	K	A	Q	I	E	F	N	P	A	W	V	T	E	Y	R	Q	I	G	Y
Secondary structure
SS confidence
Disorder											?																																								?		?					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		E	K	R	Q	L	R	V	E	H	F	N	N	D	N	V	D	A	G	D	I	G	A	G	K	H	I	T	L	L	F	E	L	T	L	N	G	Q	K	A	S	I	D	K	L	R	Y	A	P	D	N	K	L	A	K	S	D	K	T	K	E
Secondary structure
SS confidence
Disorder		?	?	?	?			?	?																														?	?		?									?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		L	A	W	L	K	I	R	W	K	Y	P	Q	G	K	E	S	Q	L	V	E	F	P	L	G	P	T	I	N	A	P	S	E	D	M	R	F	R	A	A	V	A	A	Y	G	Q	K	L	R	G	S	E	Y	L	N	N	T	S	W	Q	Q
Secondary structure
SS confidence
Disorder														?									?	?	?	?	?	?	?	?	?	?																	?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.
Sequence		I	K	Q	W	A	Q	Q	A	K	G	E	D	P	Q	G	Y	R	A	E	F	I	R	L	I	E	L	A	D	G	V	T	D	I	S	Q
Secondary structure
SS confidence
Disorder									?	?	?	?	?	?	?																		?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1rs0 chain A Region: 214 - 395 Aligned: 180 Modelled: 182 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) Phyre2 PDB 2ok5 chain A Region: 204 - 391 Aligned: 185 Modelled: 185 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b Phyre2 PDB 3ibs chain A Region: 215 - 393 Aligned: 171 Modelled: 178 Confidence: 100.0% Identity: 30% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron Phyre2 PDB 2ok5 chain A domain 1 Region: 204 - 396 Aligned: 190 Modelled: 190 Confidence: 100.0% Identity: 19% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 2i6s chain A Region: 206 - 390 Aligned: 177 Modelled: 185 Confidence: 99.9% Identity: 19% PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a Phyre2 PDB 2x5n chain A Region: 217 - 378 Aligned: 158 Modelled: 162 Confidence: 99.9% Identity: 18% PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain Phyre2 PDB 2x31 chain F Region: 210 - 390 Aligned: 177 Modelled: 181 Confidence: 99.9% Identity: 21% PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang Phyre2 PDB 1shu chain X Region: 212 - 394 Aligned: 177 Modelled: 181 Confidence: 99.9% Identity: 22% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1pd0 chain A domain 3 Region: 214 - 395 Aligned: 177 Modelled: 182 Confidence: 99.9% Identity: 16% Fold: vWA-like Superfamily: vWA-like Family: Trunk domain of Sec23/24 Phyre2 PDB 1ijb chain A Region: 214 - 395 Aligned: 178 Modelled: 182 Confidence: 99.9% Identity: 14% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1u0o chain C domain 1 Region: 212 - 394 Aligned: 179 Modelled: 183 Confidence: 99.9% Identity: 17% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 3n2n chain C Region: 212 - 394 Aligned: 177 Modelled: 181 Confidence: 99.9% Identity: 20% PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain Phyre2 PDB 3gxb chain B Region: 214 - 394 Aligned: 166 Modelled: 181 Confidence: 99.9% Identity: 15% PDB header:cell adhesion Chain: B: PDB Molecule:von willebrand factor; PDBTitle: crystal structure of vwf a2 domain Phyre2 PDB 2iue chain A Region: 214 - 393 Aligned: 174 Modelled: 177 Confidence: 99.9% Identity: 17% PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold Phyre2 PDB 2b2x chain B Region: 215 - 394 Aligned: 171 Modelled: 180 Confidence: 99.9% Identity: 15% PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab Phyre2 PDB 1q0p chain A Region: 214 - 378 Aligned: 163 Modelled: 165 Confidence: 99.9% Identity: 21% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1jey chain A domain 2 Region: 217 - 356 Aligned: 138 Modelled: 140 Confidence: 99.8% Identity: 19% Fold: vWA-like Superfamily: vWA-like Family: Ku70 subunit N-terminal domain Phyre2 PDB 1atz chain A Region: 213 - 387 Aligned: 167 Modelled: 175 Confidence: 99.8% Identity: 15% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1jey chain B domain 2 Region: 217 - 356 Aligned: 136 Modelled: 140 Confidence: 99.8% Identity: 15% Fold: vWA-like Superfamily: vWA-like Family: Ku80 subunit N-terminal domain Phyre2 PDB 1ck4 chain A Region: 214 - 393 Aligned: 172 Modelled: 180 Confidence: 99.8% Identity: 16% Fold: vWA-like Superfamily: vWA-like Family: Integrin A (or I) domain Phyre2 PDB 1pd0 chain A Region: 202 - 559 Aligned: 327 Modelled: 327 Confidence: 99.7% Identity: 14% PDB header:transport protein Chain: A: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the copii coat subunit, sec24,2 complexed with a peptide from the snare protein sed53 (yeast syntaxin-5) Phyre2 1 c1rs0A_ 2 c2ok5A_ 3 c3ibsA_ 4 d2ok5a1 5 c2i6sA_ 6 c2x5nA_ 7 c2x31F_ 8 d1shux_ 9 d1pd0a3 10 d1ijba_ 11 d1u0oc1 12 c3n2nC_ 13 c3gxbB_ 14 c2iueA_ 15 c2b2xB_ 16 d1q0pa_ 17 d1jeya2 18 d1atza_ 19 d1jeyb2 20 d1ck4a_ 21 22 23 24 25 26 27 28 29 c1pd0A_ 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1rs0A_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: crystal structure analysis of the bb segment of factor b2 complexed with di-isopropyl-phosphate (dip) 2 c2ok5A_ 100.0 21 PDB header:hydrolase Chain: A: PDB Molecule:complement factor b; PDBTitle: human complement factor b 3 c3ibsA_ 100.0 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein batb; PDBTitle: crystal structure of conserved hypothetical protein batb from2 bacteroides thetaiotaomicron 4 d2ok5a1 100.0 19 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 5 c2i6sA_ 99.9 19 PDB header:hydrolase Chain: A: PDB Molecule:complement c2a fragment; PDBTitle: complement component c2a 6 c2x5nA_ 99.9 18 PDB header:nuclear protein Chain: A: PDB Molecule:26s proteasome regulatory subunit rpn10; PDBTitle: crystal structure of the sprpn10 vwa domain 7 c2x31F_ 99.9 21 PDB header:ligase Chain: F: PDB Molecule:magnesium-chelatase 60 kda subunit; PDBTitle: modelling of the complex between subunits bchi and bchd of magnesium2 chelatase based on single-particle cryo-em reconstruction at 7.5 ang 8 d1shux_ 99.9 22 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 9 d1pd0a3 99.9 16 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 10 d1ijba_ 99.9 14 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 11 d1u0oc1 99.9 17 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 12 c3n2nC_ 99.9 20 PDB header:toxin receptor Chain: C: PDB Molecule:anthrax toxin receptor 1; PDBTitle: the crystal structure of tumor endothelial marker 8 (tem8)2 extracellular domain 13 c3gxbB_ 99.9 15 PDB header:cell adhesion Chain: B: PDB Molecule:von willebrand factor; PDBTitle: crystal structure of vwf a2 domain 14 c2iueA_ 99.9 17 PDB header:membrane protein Chain: A: PDB Molecule:pactolus i-domain; PDBTitle: pactolus i-domain: functional switching of the rossmann2 fold 15 c2b2xB_ 99.9 15 PDB header:immune system Chain: B: PDB Molecule:integrin alpha-1; PDBTitle: vla1 rdeltah i-domain complexed with a quadruple mutant of the aqc22 fab 16 d1q0pa_ 99.9 21 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 17 d1jeya2 99.8 19 Fold:vWA-like Superfamily:vWA-like Family:Ku70 subunit N-terminal domain 18 d1atza_ 99.8 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 19 d1jeyb2 99.8 15 Fold:vWA-like Superfamily:vWA-like Family:Ku80 subunit N-terminal domain 20 d1ck4a_ 99.8 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 21 d1v7pc_ not modelled 99.8 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 22 d1n3ya_ not modelled 99.8 14 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 23 c2xggB_ not modelled 99.8 28 PDB header:hydrolase Chain: B: PDB Molecule:microneme protein 2; PDBTitle: structure of toxoplasma gondii micronemal protein 2 a_i2 domain 24 d1pt6a_ not modelled 99.8 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 25 d1yvra2 not modelled 99.8 15 Fold:vWA-like Superfamily:vWA-like Family:RoRNP C-terminal domain-like 26 d1mf7a_ not modelled 99.7 16 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 27 d1mjna_ not modelled 99.7 15 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 28 c2nvoA_ not modelled 99.7 16 PDB header:rna binding protein Chain: A: PDB Molecule:ro sixty-related protein, rsr; PDBTitle: crystal structure of deinococcus radiodurans ro (rsr) protein 29 c1pd0A_ 99.7 14 PDB header:transport protein Chain: A: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the copii coat subunit, sec24,2 complexed with a peptide from the snare protein sed53 (yeast syntaxin-5) 30 c1m2vB_ not modelled 99.6 13 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24; PDBTitle: crystal structure of the yeast sec23/24 heterodimer 31 c3eh2B_ not modelled 99.6 14 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24c; PDBTitle: crystal structure of the human copii-coat protein sec24c 32 c3egxB_ not modelled 99.6 13 PDB header:protein transport Chain: B: PDB Molecule:protein transport protein sec24a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23a/24a complexed with the snare protein sec22b and3 bound to the transport signal sequence of the snare protein4 bet1 33 c3eg9B_ not modelled 99.6 14 PDB header:protein transport Chain: B: PDB Molecule:sec24 related gene family, member d; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 34 c3eg9A_ not modelled 99.6 14 PDB header:protein transport Chain: A: PDB Molecule:protein transport protein sec23a; PDBTitle: crystal structure of the mammalian copii-coat protein2 sec23/24 bound to the transport signal sequence of membrin 35 c1jeyB_ not modelled 99.6 13 PDB header:dna binding protein/dna Chain: B: PDB Molecule:ku80; PDBTitle: crystal structure of the ku heterodimer bound to dna 36 c1m2oA_ not modelled 99.6 18 PDB header:protein transport/signaling protein Chain: A: PDB Molecule:protein transport protein sec23; PDBTitle: crystal structure of the sec23-sar1 complex 37 d1tyeb2 not modelled 99.6 20 Fold:vWA-like Superfamily:vWA-like Family:Integrin A (or I) domain 38 c3v4pB_ not modelled 99.5 16 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-7; PDBTitle: crystal structure of a4b7 headpiece complexed with fab act-1 39 d2qtva3 not modelled 99.5 18 Fold:vWA-like Superfamily:vWA-like Family:Trunk domain of Sec23/24 40 c3fcuB_ not modelled 99.5 17 PDB header:cell adhesion/blood clotting Chain: B: PDB Molecule:integrin beta-3; PDBTitle: structure of headpiece of integrin aiibb3 in open conformation 41 c3ragA_ not modelled 99.4 22 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein aaci_0196 from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446 42 c1jeqA_ not modelled 99.2 16 PDB header:dna binding protein Chain: A: PDB Molecule:ku70; PDBTitle: crystal structure of the ku heterodimer 43 c1u8cB_ not modelled 99.1 18 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-3; PDBTitle: a novel adaptation of the integrin psi domain revealed from its2 crystal structure 44 c1yvrA_ not modelled 99.0 16 PDB header:rna binding protein Chain: A: PDB Molecule:60-kda ss-a/ro ribonucleoprotein; PDBTitle: ro autoantigen 45 c3k6sB_ not modelled 98.6 16 PDB header:cell adhesion Chain: B: PDB Molecule:integrin beta-2; PDBTitle: structure of integrin alphaxbeta2 ectodomain 46 d1vlpa2 not modelled 53.2 13 Fold:TIM beta/alpha-barrel Superfamily:Nicotinate/Quinolinate PRTase C-terminal domain-like Family:Monomeric nicotinate phosphoribosyltransferase C-terminal domain 47 d1o98a1 not modelled 49.3 20 Fold:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Superfamily:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Family:2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain 48 d1jsca3 not modelled 48.7 14 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 49 d2fcja1 not modelled 48.5 17 Fold:Toprim domain Superfamily:Toprim domain Family:Toprim domain 50 c2e5cA_ not modelled 48.3 25 PDB header:transferase Chain: A: PDB Molecule:nicotinamide phosphoribosyltransferase; PDBTitle: crystal structure of human nmprtase complexed with 5'-phosphoribosyl-2 1'-pyrophosphate 51 c1vlpA_ not modelled 41.1 14 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: crystal structure of a putative nicotinate phosphoribosyltransferase2 (yor209c, npt1) from saccharomyces cerevisiae at 1.75 a resolution 52 d2hk6a1 not modelled 35.8 9 Fold:Chelatase-like Superfamily:Chelatase Family:Ferrochelatase 53 d1xpma1 not modelled 32.1 10 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 54 c3d3kD_ not modelled 30.4 15 PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 55 c3igzB_ not modelled 26.2 15 PDB header:isomerase Chain: B: PDB Molecule:cofactor-independent phosphoglycerate mutase; PDBTitle: crystal structures of leishmania mexicana phosphoglycerate2 mutase at low cobalt concentration 56 c2bdqA_ not modelled 25.3 16 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 57 c3lq1A_ not modelled 24.1 14 PDB header:transferase Chain: A: PDB Molecule:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- PDBTitle: crystal structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene2 1-carboxylic acid synthase/2-oxoglutarate decarboxylase3 from listeria monocytogenes str. 4b f2365 58 c1m6yA_ not modelled 23.2 18 PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah 59 c1iszA_ not modelled 21.1 21 PDB header:hydrolase Chain: A: PDB Molecule:endo-1,4-beta-d-xylanase; PDBTitle: crystal structure of xylanase from streptomyces2 olivaceoviridis e-86 complexed with galactose 60 c1txtB_ not modelled 20.0 11 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 61 c2dunA_ not modelled 19.7 13 PDB header:transferase Chain: A: PDB Molecule:dna polymerase mu; PDBTitle: solution structure of brct domain of dna polymerase mu 62 c1t10A_ not modelled 19.6 12 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: phosphoglucose isomerase from leishmania mexicana in complex with2 substrate d-fructose-6-phosphate 63 c2coeA_ not modelled 19.3 6 PDB header:transferase Chain: A: PDB Molecule:deoxynucleotidyltransferase, terminal variant; PDBTitle: solution structure of brct domain of terminal2 deoxynucleotidyltransferase 64 d2ihta3 not modelled 18.9 19 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 65 d1hm5a_ not modelled 18.6 16 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 66 c1wg8B_ not modelled 18.0 10 PDB header:transferase Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8. 67 c3euoB_ not modelled 17.8 20 PDB header:transferase Chain: B: PDB Molecule:type iii pentaketide synthase; PDBTitle: crystal structure of a fungal type iii polyketide synthase,2 oras 68 c1o98A_ not modelled 17.6 20 PDB header:isomerase Chain: A: PDB Molecule:2,3-bisphosphoglycerate-independent PDBTitle: 1.4a crystal structure of phosphoglycerate mutase from2 bacillus stearothermophilus complexed with3 2-phosphoglycerate 69 d1r85a_ not modelled 17.2 25 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 70 c3os4A_ not modelled 15.8 17 PDB header:transferase Chain: A: PDB Molecule:nicotinate phosphoribosyltransferase; PDBTitle: the crystal structure of nicotinate phosphoribosyltransferase from2 yersinia pestis 71 c2gfqC_ not modelled 15.6 16 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:upf0204 protein ph0006; PDBTitle: structure of protein of unknown function ph0006 from pyrococcus2 horikoshii 72 d2csua1 not modelled 15.3 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 73 c1jscA_ not modelled 15.3 13 PDB header:lyase Chain: A: PDB Molecule:acetohydroxy-acid synthase; PDBTitle: crystal structure of the catalytic subunit of yeast2 acetohydroxyacid synthase: a target for herbicidal3 inhibitors 74 d1u0fa_ not modelled 15.3 19 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 75 c1tllA_ not modelled 14.3 13 PDB header:oxidoreductase Chain: A: PDB Molecule:nitric-oxide synthase, brain; PDBTitle: crystal structure of rat neuronal nitric-oxide synthase2 reductase module at 2.3 a resolution. 76 c1x9eB_ not modelled 14.0 10 PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis 77 c3hjbA_ not modelled 13.8 13 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: 1.5 angstrom crystal structure of glucose-6-phosphate isomerase from2 vibrio cholerae. 78 c3nbuC_ not modelled 13.4 16 PDB header:isomerase Chain: C: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: crystal structure of pgi glucosephosphate isomerase 79 c2jvfA_ not modelled 13.0 18 PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein 80 d1iata_ not modelled 12.7 19 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 81 c2p8uB_ not modelled 12.6 15 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i 82 c1nuiA_ not modelled 12.2 17 PDB header:replication Chain: A: PDB Molecule:dna primase/helicase; PDBTitle: crystal structure of the primase fragment of bacteriophage t7 primase-2 helicase protein 83 c2i2xD_ not modelled 12.1 12 PDB header:transferase Chain: D: PDB Molecule:methyltransferase 1; PDBTitle: crystal structure of methanol:cobalamin methyltransferase complex2 mtabc from methanosarcina barkeri 84 c3ugsB_ not modelled 12.1 14 PDB header:transferase Chain: B: PDB Molecule:undecaprenyl pyrophosphate synthase; PDBTitle: crystal structure of a probable undecaprenyl diphosphate synthase2 (upps) from campylobacter jejuni 85 c2og2A_ not modelled 11.9 16 PDB header:protein transport Chain: A: PDB Molecule:putative signal recognition particle receptor; PDBTitle: crystal structure of chloroplast ftsy from arabidopsis2 thaliana 86 d1twda_ not modelled 11.8 21 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 87 c3hl0B_ not modelled 11.7 14 PDB header:oxidoreductase Chain: B: PDB Molecule:maleylacetate reductase; PDBTitle: crystal structure of maleylacetate reductase from agrobacterium2 tumefaciens 88 d1isia_ not modelled 11.6 21 Fold:Flavodoxin-like Superfamily:N-(deoxy)ribosyltransferase-like Family:ADP ribosyl cyclase-like 89 c2vjjA_ not modelled 11.6 15 PDB header:viral protein Chain: A: PDB Molecule:tailspike protein; PDBTitle: tailspike protein of e.coli bacteriophage hk620 in complex2 with hexasaccharide 90 d2ji7a3 not modelled 11.3 15 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 91 d1gzda_ not modelled 11.2 17 Fold:SIS domain Superfamily:SIS domain Family:Phosphoglucose isomerase, PGI 92 c2wu8A_ not modelled 11.1 16 PDB header:isomerase Chain: A: PDB Molecule:glucose-6-phosphate isomerase; PDBTitle: structural studies of phosphoglucose isomerase from2 mycobacterium tuberculosis h37rv 93 c3ca8B_ not modelled 11.0 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ydcf; PDBTitle: crystal structure of escherichia coli ydcf, an s-adenosyl-l-methionine2 utilizing enzyme 94 c3lklB_ not modelled 11.0 15 PDB header:transport protein Chain: B: PDB Molecule:antisigma-factor antagonist stas; PDBTitle: crystal structure of the c-terminal domain of anti-sigma factor2 antagonist stas from rhodobacter sphaeroides 95 c3lehA_ not modelled 10.9 14 PDB header:transferase Chain: A: PDB Molecule:putative hydroxymethylglutaryl-coa synthase; PDBTitle: the crystal structure of smu.943c from streptococcus mutans ua159 96 d1ozha3 not modelled 10.9 12 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 97 c3e1hA_ not modelled 10.7 21 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a type iii polyketide synthase2 pksiiinc from neurospora crassa 98 d1csca_ not modelled 10.5 11 Fold:Citrate synthase Superfamily:Citrate synthase Family:Citrate synthase 99 d2d1pa1 not modelled 10.5 16 Fold:DsrEFH-like Superfamily:DsrEFH-like Family:DsrEF-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0