Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	L	W	G	G	R	F	T	Q	A	A	D	Q	R	F	K	Q	F	N	D	S	L	R	F	D	Y	R	L	A	E	Q	D	I	V	G	S	V	A	W	S	K	A	L	V	T	V	G	V	L	T	A	E	E	Q	A	Q	L	E	E
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	L	N	V	L	L	E	D	V	R	A	R	P	Q	Q	I	L	E	S	D	A	E	D	I	H	S	W	V	E	G	K	L	I	D	K	V	G	Q	L	G	K	K	L	H	T	G	R	S	R	N	D	Q	V	A	T	D	L	K	L	W
Secondary structure
SS confidence
Disorder													?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	K	D	T	V	S	E	L	L	T	A	N	R	Q	L	Q	S	A	L	V	E	T	A	Q	N	N	Q	D	A	V	M	P	G	Y	T	H	L	Q	R	A	Q	P	V	T	F	A	H	W	C	L	A	Y	V	E	M	L	A	R	D	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		S	R	L	Q	D	A	L	K	R	L	D	V	S	P	L	G	C	G	A	L	A	G	T	A	Y	E	I	D	R	E	Q	L	A	G	W	L	G	F	A	S	A	T	R	N	S	L	D	S	V	S	D	R	D	H	V	L	E	L	L	S
Secondary structure
SS confidence
Disorder														?				?																								?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	A	A	I	G	M	V	H	L	S	R	F	A	E	D	L	I	F	F	N	T	G	E	A	G	F	V	E	L	S	D	R	V	T	S	G	S	S	L	M	P	Q	K	K	N	P	D	A	L	E	L	I	R	G	K	C	G	R	V	Q
Secondary structure
SS confidence
Disorder																																?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		G	A	L	T	G	M	M	M	T	L	K	G	L	P	L	A	Y	N	K	D	M	Q	E	D	K	E	G	L	F	D	A	L	D	T	W	L	D	C	L	H	M	A	A	L	V	L	D	G	I	Q	V	K	R	P	R	C	Q	E	A	A
Secondary structure
SS confidence
Disorder														?		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		Q	Q	G	Y	A	N	A	T	E	L	A	D	Y	L	V	A	K	G	V	P	F	R	E	A	H	H	I	V	G	E	A	V	V	E	A	I	R	Q	G	K	P	L	E	D	L	P	L	S	E	L	Q	K	F	S	Q	V	I	D	E	D
Secondary structure
SS confidence
Disorder																																							?														?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.
Sequence		V	Y	P	I	L	S	L	Q	S	C	L	D	K	R	A	A	K	G	G	V	S	P	Q	Q	V	A	Q	A	I	A	F	A	Q	A	R	L	G
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?	?																?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1tj7 chain A Region: 3 - 457 Aligned: 455 Modelled: 455 Confidence: 100.0% Identity: 100% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1i0a chain A Region: 6 - 456 Aligned: 449 Modelled: 451 Confidence: 100.0% Identity: 41% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1tjv chain A Region: 12 - 456 Aligned: 443 Modelled: 445 Confidence: 100.0% Identity: 44% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1k62 chain A Region: 10 - 456 Aligned: 445 Modelled: 447 Confidence: 100.0% Identity: 44% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 2e9f chain C Region: 12 - 457 Aligned: 445 Modelled: 446 Confidence: 100.0% Identity: 50% PDB header:lyase Chain: C: PDB Molecule:argininosuccinate lyase; PDBTitle: crystal structure of t.th.hb8 argininosuccinate lyase complexed with2 l-arginine Phyre2 PDB 1hy0 chain A Region: 13 - 456 Aligned: 442 Modelled: 444 Confidence: 100.0% Identity: 43% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 2pfm chain A Region: 6 - 448 Aligned: 423 Modelled: 438 Confidence: 100.0% Identity: 18% PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of adenylosuccinate lyase (purb) from bacillus2 anthracis Phyre2 PDB 1c3c chain A Region: 7 - 448 Aligned: 417 Modelled: 438 Confidence: 100.0% Identity: 18% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1q5n chain A Region: 2 - 452 Aligned: 424 Modelled: 451 Confidence: 100.0% Identity: 19% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1re5 chain A Region: 2 - 455 Aligned: 430 Modelled: 441 Confidence: 100.0% Identity: 23% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 3c8t chain A Region: 3 - 450 Aligned: 417 Modelled: 433 Confidence: 100.0% Identity: 22% PDB header:lyase Chain: A: PDB Molecule:fumarate lyase; PDBTitle: crystal structure of fumarate lyase from mesorhizobium sp. bnc1 Phyre2 PDB 1fuo chain A Region: 2 - 429 Aligned: 409 Modelled: 415 Confidence: 100.0% Identity: 20% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1j3u chain A Region: 2 - 441 Aligned: 414 Modelled: 436 Confidence: 100.0% Identity: 20% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 2vd6 chain B Region: 6 - 451 Aligned: 415 Modelled: 436 Confidence: 100.0% Identity: 17% PDB header:lyase Chain: B: PDB Molecule:adenylosuccinate lyase; PDBTitle: human adenylosuccinate lyase in complex with its substrate2 n6-(1,2-dicarboxyethyl)-amp, and its products amp and3 fumarate. Phyre2 PDB 1yfm chain A Region: 2 - 431 Aligned: 410 Modelled: 430 Confidence: 100.0% Identity: 20% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 1yfm chain A Region: 2 - 431 Aligned: 410 Modelled: 430 Confidence: 100.0% Identity: 20% PDB header:lyase Chain: A: PDB Molecule:fumarase; PDBTitle: recombinant yeast fumarase Phyre2 PDB 1vdk chain A Region: 2 - 440 Aligned: 411 Modelled: 430 Confidence: 100.0% Identity: 20% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 3no9 chain C Region: 2 - 433 Aligned: 413 Modelled: 432 Confidence: 100.0% Identity: 19% PDB header:lyase Chain: C: PDB Molecule:fumarate hydratase class ii; PDBTitle: crystal structure of apo fumarate hydratase from mycobacterium2 tuberculosis Phyre2 PDB 1jsw chain A Region: 6 - 426 Aligned: 406 Modelled: 412 Confidence: 100.0% Identity: 19% Fold: L-aspartase-like Superfamily: L-aspartase-like Family: L-aspartase/fumarase Phyre2 PDB 2qga chain C Region: 6 - 451 Aligned: 419 Modelled: 444 Confidence: 100.0% Identity: 16% PDB header:lyase Chain: C: PDB Molecule:adenylosuccinate lyase; PDBTitle: plasmodium vivax adenylosuccinate lyase pv003765 with amp bound Phyre2 1 d1tj7a_ 2 d1i0aa_ 3 d1tjva_ 4 d1k62a_ 5 c2e9fC_ 6 d1hy0a_ 7 c2pfmA_ 8 d1c3ca_ 9 d1q5na_ 10 d1re5a_ 11 c3c8tA_ 12 d1fuoa_ 13 d1j3ua_ 14 c2vd6B_ 15 d1yfma_ 16 c1yfmA_ 17 d1vdka_ 18 c3no9C_ 19 d1jswa_ 20 c2qgaC_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tj7a_ 100.0 100 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 2 d1i0aa_ 100.0 41 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 3 d1tjva_ 100.0 44 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 4 d1k62a_ 100.0 44 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 5 c2e9fC_ 100.0 50 PDB header:lyase Chain: C: PDB Molecule:argininosuccinate lyase; PDBTitle: crystal structure of t.th.hb8 argininosuccinate lyase complexed with2 l-arginine 6 d1hy0a_ 100.0 43 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 7 c2pfmA_ 100.0 18 PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of adenylosuccinate lyase (purb) from bacillus2 anthracis 8 d1c3ca_ 100.0 18 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 9 d1q5na_ 100.0 19 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 10 d1re5a_ 100.0 23 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 11 c3c8tA_ 100.0 22 PDB header:lyase Chain: A: PDB Molecule:fumarate lyase; PDBTitle: crystal structure of fumarate lyase from mesorhizobium sp. bnc1 12 d1fuoa_ 100.0 20 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 13 d1j3ua_ 100.0 20 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 14 c2vd6B_ 100.0 17 PDB header:lyase Chain: B: PDB Molecule:adenylosuccinate lyase; PDBTitle: human adenylosuccinate lyase in complex with its substrate2 n6-(1,2-dicarboxyethyl)-amp, and its products amp and3 fumarate. 15 d1yfma_ 100.0 20 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 16 c1yfmA_ 100.0 20 PDB header:lyase Chain: A: PDB Molecule:fumarase; PDBTitle: recombinant yeast fumarase 17 d1vdka_ 100.0 20 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 18 c3no9C_ 100.0 19 PDB header:lyase Chain: C: PDB Molecule:fumarate hydratase class ii; PDBTitle: crystal structure of apo fumarate hydratase from mycobacterium2 tuberculosis 19 d1jswa_ 100.0 19 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 20 c2qgaC_ 100.0 16 PDB header:lyase Chain: C: PDB Molecule:adenylosuccinate lyase; PDBTitle: plasmodium vivax adenylosuccinate lyase pv003765 with amp bound 21 c3ocfB_ not modelled 100.0 22 PDB header:lyase Chain: B: PDB Molecule:fumarate lyase:delta crystallin; PDBTitle: crystal structure of fumarate lyase:delta crystallin from brucella2 melitensis in native form 22 d1dofa_ not modelled 100.0 19 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 23 c3bhgA_ not modelled 100.0 16 PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of adenylosuccinate lyase from legionella2 pneumophila 24 d1jswc_ not modelled 100.0 19 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 25 c2ptsA_ not modelled 100.0 18 PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: crystal structure of wild type escherichia coli adenylosuccinate lyase 26 c1yisA_ not modelled 100.0 15 PDB header:lyase Chain: A: PDB Molecule:adenylosuccinate lyase; PDBTitle: structural genomics of caenorhabditis elegans: adenylosuccinate lyase 27 c3e04C_ not modelled 100.0 19 PDB header:lyase Chain: C: PDB Molecule:fumarate hydratase; PDBTitle: crystal structure of human fumarate hydratase 28 c3gtdB_ not modelled 100.0 18 PDB header:lyase Chain: B: PDB Molecule:fumarate hydratase class ii; PDBTitle: 2.4 angstrom crystal structure of fumarate hydratase from rickettsia2 prowazekii 29 c2fenA_ not modelled 100.0 17 PDB header:isomerase Chain: A: PDB Molecule:3-carboxy-cis,cis-muconate lactonizing enzyme; PDBTitle: 3-carboxy-cis,cis-muconate lactonizing enzyme from agrobacterium2 radiobacter s2 30 d1f1oa_ not modelled 100.0 19 Fold:L-aspartase-like Superfamily:L-aspartase-like Family:L-aspartase/fumarase 31 c3r6yG_ not modelled 100.0 21 PDB header:lyase Chain: G: PDB Molecule:aspartase; PDBTitle: crystal structure of chymotrypsin-treated aspartase from bacillus sp.2 ym55-1 32 c2rcyB_ not modelled 61.8 22 PDB header:oxidoreductase Chain: B: PDB Molecule:pyrroline carboxylate reductase; PDBTitle: crystal structure of plasmodium falciparum pyrroline carboxylate2 reductase (mal13p1.284) with nadp bound 33 c1x5bA_ not modelled 50.7 29 PDB header:protein binding Chain: A: PDB Molecule:signal transducing adaptor molecule 2; PDBTitle: the solution structure of the vhs domain of human signal2 transducing adaptor molecule 2 34 d2ahra1 not modelled 38.0 28 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:ProC C-terminal domain-like 35 d2di4a1 not modelled 33.6 18 Fold:FtsH protease domain-like Superfamily:FtsH protease domain-like Family:FtsH protease domain-like 36 d1yqga1 not modelled 32.1 25 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:ProC C-terminal domain-like 37 c2ctoA_ not modelled 30.2 58 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:novel protein; PDBTitle: solution structure of the hmg box like domain from human2 hypothetical protein flj14904 38 c2xgvA_ not modelled 27.8 28 PDB header:viral protein Chain: A: PDB Molecule:psiv capsid n-terminal domain; PDBTitle: structure of the n-terminal domain of capsid protein from2 rabbit endogenous lentivirus (relik) 39 d1u5ta1 not modelled 22.9 23 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:Vacuolar sorting protein domain 40 c1p74B_ not modelled 19.6 16 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase (aroe) from2 haemophilus influenzae 41 d1nvta2 not modelled 19.0 14 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like 42 c3fbtB_ not modelled 18.7 13 PDB header:oxidoreductase, lyase Chain: B: PDB Molecule:chorismate mutase and shikimate 5-dehydrogenase PDBTitle: crystal structure of a chorismate mutase/shikimate 5-2 dehydrogenase fusion protein from clostridium3 acetobutylicum 43 d1vi2a2 not modelled 16.5 15 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like 44 c3bbnC_ not modelled 16.1 63 PDB header:ribosome Chain: C: PDB Molecule:ribosomal protein s3; PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome. 45 c2vs0B_ not modelled 15.6 10 PDB header:cell invasion Chain: B: PDB Molecule:virulence factor esxa; PDBTitle: structural analysis of homodimeric staphylococcal aureus2 virulence factor esxa 46 d1npya2 not modelled 15.1 21 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like 47 c3pgjB_ not modelled 14.9 17 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.49 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. n169613 in complex with shikimate 48 c2ev9B_ not modelled 14.9 15 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from thermus2 thermophilus hb8 in complex with nadp(h) and shikimate 49 c2zmeA_ not modelled 14.4 13 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 50 d1phza2 not modelled 14.4 22 Fold:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Superfamily:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Family:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 51 d1g3pa2 not modelled 14.3 33 Fold:N-terminal domains of the minor coat protein g3p Superfamily:N-terminal domains of the minor coat protein g3p Family:N-terminal domains of the minor coat protein g3p 52 c1nvtA_ not modelled 14.0 14 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5'-dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase (aroe or2 mj1084) in complex with nadp+ 53 d2ga1a1 not modelled 13.8 24 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Alr1493-like 54 c3o8qB_ not modelled 13.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha; PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae 55 c3tozA_ not modelled 13.5 27 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad. 56 c2nloA_ not modelled 13.5 16 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of the quinate dehydrogenase from corynebacterium2 glutamicum 57 c2hk8B_ not modelled 12.9 20 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from aquifex2 aeolicus at 2.35 angstrom resolution 58 c2ag8A_ not modelled 12.8 13 PDB header:oxidoreductase Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase; PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis 59 d1mlwa_ not modelled 12.3 17 Fold:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Superfamily:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Family:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 60 c1u5tA_ not modelled 12.1 23 PDB header:transport protein Chain: A: PDB Molecule:appears to be functionally related to snf7; PDBTitle: structure of the escrt-ii endosomal trafficking complex 61 c3e2tA_ not modelled 11.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:tryptophan 5-hydroxylase 1; PDBTitle: the catalytic domain of chicken tryptophan hydroxylase 12 with bound tryptophan 62 d1dlja1 not modelled 11.4 20 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:UDP-glucose/GDP-mannose dehydrogenase dimerisation domain 63 c1wjvA_ not modelled 11.2 56 PDB header:dna binding protein Chain: A: PDB Molecule:cell growth regulating nucleolar protein lyar; PDBTitle: solution structure of the n-terminal zinc finger domain of2 mouse cell growth regulating nucleolar protein lyar 64 d1j8ua_ not modelled 11.2 22 Fold:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Superfamily:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Family:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 65 c3gt0A_ not modelled 11.1 26 PDB header:oxidoreductase Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase; PDBTitle: crystal structure of pyrroline 5-carboxylate reductase from bacillus2 cereus. northeast structural genomics consortium target bcr38b 66 d2qalc1 not modelled 11.0 38 Fold:Alpha-lytic protease prodomain-like Superfamily:Prokaryotic type KH domain (KH-domain type II) Family:Prokaryotic type KH domain (KH-domain type II) 67 c3pwzA_ not modelled 10.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase 3; PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida 68 c2eggA_ not modelled 10.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: crystal structure of shikimate 5-dehydrogenase (aroe) from2 geobacillus kaustophilus 69 d1p77a2 not modelled 10.8 15 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like 70 d1k6ya1 not modelled 10.7 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase 71 c1nytC_ not modelled 10.7 18 PDB header:oxidoreductase Chain: C: PDB Molecule:shikimate 5-dehydrogenase; PDBTitle: shikimate dehydrogenase aroe complexed with nadp+ 72 c3cuqA_ not modelled 10.5 13 PDB header:protein transport Chain: A: PDB Molecule:vacuolar-sorting protein snf8; PDBTitle: integrated structural and functional model of the human escrt-ii2 complex 73 d1e0ea_ not modelled 10.5 35 Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase 74 d2qy9a1 not modelled 10.5 21 Fold:Four-helical up-and-down bundle Superfamily:Domain of the SRP/SRP receptor G-proteins Family:Domain of the SRP/SRP receptor G-proteins 75 c3u62A_ not modelled 10.4 15 PDB header:oxidoreductase Chain: A: PDB Molecule:shikimate dehydrogenase; PDBTitle: crystal structure of shikimate dehydrogenase from thermotoga maritima 76 c1npyA_ not modelled 10.4 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical shikimate 5-dehydrogenase-like PDBTitle: structure of shikimate 5-dehydrogenase-like protein hi0607 77 c3ke2A_ not modelled 10.3 19 PDB header:unknown function Chain: A: PDB Molecule:uncharacterized protein yp_928783.1; PDBTitle: crystal structure of a duf2131 family protein (sama_2911) from2 shewanella amazonensis sb2b at 2.50 a resolution 78 d1q3ma_ not modelled 10.0 33 Fold:GLA-domain Superfamily:GLA-domain Family:GLA-domain 79 d1nyta2 not modelled 9.9 15 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Shikimate dehydrogenase-like 80 d1wjfa_ not modelled 9.9 20 Fold:DNA/RNA-binding 3-helical bundle Superfamily:N-terminal Zn binding domain of HIV integrase Family:N-terminal Zn binding domain of HIV integrase 81 c2o8kA_ not modelled 9.4 23 PDB header:transcription/dna Chain: A: PDB Molecule:rna polymerase sigma factor rpon; PDBTitle: nmr structure of the sigma-54 rpon domain bound to the-242 promoter element 82 c3hfrA_ not modelled 9.0 24 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of glutamate racemase from listeria monocytogenes 83 d1vkma_ not modelled 9.0 15 Fold:Indigoidine synthase A-like Superfamily:Indigoidine synthase A-like Family:Indigoidine synthase A-like 84 d1ltza_ not modelled 9.0 25 Fold:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Superfamily:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains Family:Aromatic aminoacid monoxygenases, catalytic and oligomerization domains 85 c3c24A_ not modelled 9.0 12 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution 86 c2jfqA_ not modelled 8.8 24 PDB header:isomerase Chain: A: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of staphylococcus aureus glutamate2 racemase in complex with d-glutamate 87 d2voua2 not modelled 8.8 12 Fold:FAD-linked reductases, C-terminal domain Superfamily:FAD-linked reductases, C-terminal domain Family:PHBH-like 88 c1dipA_ not modelled 8.8 22 PDB header:acetylation Chain: A: PDB Molecule:delta-sleep-inducing peptide immunoreactive PDBTitle: the solution structure of porcine delta-sleep-inducing2 peptide immunoreactive peptide, nmr, 10 structures 89 c3m1eA_ not modelled 8.7 11 PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator benm; PDBTitle: crystal structure of benm_dbd 90 c2gzmB_ not modelled 8.2 21 PDB header:isomerase Chain: B: PDB Molecule:glutamate racemase; PDBTitle: crystal structure of the glutamate racemase from bacillus2 anthracis 91 c1vi2B_ not modelled 8.1 15 PDB header:oxidoreductase Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2; PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad 92 c3lq9B_ not modelled 7.7 20 PDB header:signaling protein Chain: B: PDB Molecule:dna-damage-inducible transcript 4 protein; PDBTitle: crystal strucure of human redd1, a hypoxia-induced regulator2 of mtor 93 d1sxjb1 not modelled 7.6 14 Fold:post-AAA+ oligomerization domain-like Superfamily:post-AAA+ oligomerization domain-like Family:DNA polymerase III clamp loader subunits, C-terminal domain 94 d1v5pa_ not modelled 7.5 50 Fold:PH domain-like barrel Superfamily:PH domain-like Family:Pleckstrin-homology domain (PH domain) 95 c3eq5G_ not modelled 7.3 29 PDB header:signaling protein Chain: G: PDB Molecule:ski-like protein; PDBTitle: crystal structure of fragment 137 to 238 of the human ski-like protein 96 d1q8ha_ not modelled 7.3 29 Fold:GLA-domain Superfamily:GLA-domain Family:GLA-domain 97 c1q8hA_ not modelled 7.3 29 PDB header:metal binding protein Chain: A: PDB Molecule:osteocalcin; PDBTitle: crystal structure of porcine osteocalcin 98 c2p9xB_ not modelled 7.3 25 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:hypothetical protein ph0832; PDBTitle: crystal structure of ph0832 from pyrococcus horikoshii ot3 99 c2v27A_ not modelled 7.3 21 PDB header:oxidoreductase Chain: A: PDB Molecule:phenylalanine hydroxylase; PDBTitle: structure of the cold active phenylalanine hydroxylase from2 colwellia psychrerythraea 34h

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0