Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP60716
DateThu Jan 5 12:07:02 GMT 2012
Unique Job ID385ba29e472c656a

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3cixA_
Top template information
PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
Confidence and coverage
Confidence: 99.9% Coverage: 61%
195 residues ( 61% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMR
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Disorder  ?????????????????????
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   .........70.........80.........90.........100.........110.........120
Sequence  KNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLA
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Disorder 

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   .........130.........140.........150.........160.........170.........180
Sequence  QTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRAL
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?

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   .........190.........200.........210.........220.........230.........240
Sequence  DILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGE
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   .........250.........260.........270.........280.........290.........300
Sequence  TNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAA
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   .........310.........320.
Sequence  CGPFVRSSYHADLQAKGMEVK
Secondary structure 




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Disorder 

















???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3cix chain A

3D model

Region: 86 - 292
Aligned: 195
Modelled: 207
Confidence: 99.9%
Identity: 20%
PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate

Phyre2

PDB 1r30 chain A

3D model

Region: 84 - 294
Aligned: 202
Modelled: 211
Confidence: 99.9%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:biotin synthase;
PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme

Phyre2

PDB 1r30 chain A

3D model

Region: 84 - 294
Aligned: 202
Modelled: 211
Confidence: 99.9%
Identity: 17%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: Biotin synthase

Phyre2

PDB 2qgq chain F

3D model

Region: 98 - 269
Aligned: 172
Modelled: 172
Confidence: 99.9%
Identity: 12%
PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:protein tm_1862;
PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77

Phyre2

PDB 3t7v chain A

3D model

Region: 86 - 292
Aligned: 200
Modelled: 207
Confidence: 99.9%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)

Phyre2

PDB 1olt chain A

3D model

Region: 94 - 317
Aligned: 222
Modelled: 224
Confidence: 99.8%
Identity: 19%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: Oxygen-independent coproporphyrinogen III oxidase HemN

Phyre2

PDB 1tv8 chain A

3D model

Region: 87 - 294
Aligned: 199
Modelled: 206
Confidence: 99.8%
Identity: 13%
Fold: TIM beta/alpha-barrel
Superfamily: Radical SAM enzymes
Family: MoCo biosynthesis proteins

Phyre2

PDB 3c8f chain A

3D model

Region: 81 - 300
Aligned: 212
Modelled: 219
Confidence: 99.7%
Identity: 13%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme;
PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet

Phyre2

PDB 3rfa chain A

3D model

Region: 80 - 296
Aligned: 209
Modelled: 217
Confidence: 99.6%
Identity: 13%
PDB header:oxidoreductase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n;
PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine

Phyre2

PDB 2yx0 chain A

3D model

Region: 88 - 293
Aligned: 192
Modelled: 201
Confidence: 99.5%
Identity: 16%
PDB header:metal binding protein
Chain: A: PDB Molecule:radical sam enzyme;
PDBTitle: crystal structure of p. horikoshii tyw1

Phyre2

PDB 2a5h chain C

3D model

Region: 61 - 275
Aligned: 203
Modelled: 206
Confidence: 99.4%
Identity: 15%
PDB header:isomerase
Chain: C: PDB Molecule:l-lysine 2,3-aminomutase;
PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate).

Phyre2

PDB 3can chain A

3D model

Region: 131 - 302
Aligned: 156
Modelled: 172
Confidence: 98.8%
Identity: 12%
PDB header:lyase activator
Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme;
PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482

Phyre2

PDB 2z2u chain A

3D model

Region: 94 - 297
Aligned: 176
Modelled: 196
Confidence: 98.5%
Identity: 14%
PDB header:metal binding protein
Chain: A: PDB Molecule:upf0026 protein mj0257;
PDBTitle: crystal structure of archaeal tyw1

Phyre2

PDB 3ewb chain X

3D model

Region: 101 - 262
Aligned: 151
Modelled: 162
Confidence: 97.8%
Identity: 13%
PDB header:transferase
Chain: X: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes

Phyre2

PDB 3ivu chain B

3D model

Region: 105 - 262
Aligned: 145
Modelled: 158
Confidence: 97.7%
Identity: 12%
PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og

Phyre2

PDB 3eeg chain B

3D model

Region: 111 - 262
Aligned: 143
Modelled: 152
Confidence: 97.6%
Identity: 7%
PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii

Phyre2

PDB 3ble chain A

3D model

Region: 105 - 262
Aligned: 152
Modelled: 158
Confidence: 97.4%
Identity: 13%
PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate

Phyre2

PDB 2ftp chain A

3D model

Region: 98 - 262
Aligned: 158
Modelled: 160
Confidence: 97.4%
Identity: 13%
PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa

Phyre2

PDB 1nvm chain A domain 2

3D model

Region: 108 - 262
Aligned: 141
Modelled: 155
Confidence: 97.4%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: Aldolase
Family: HMGL-like

Phyre2

PDB 2cw6 chain B

3D model

Region: 97 - 262
Aligned: 159
Modelled: 166
Confidence: 97.2%
Identity: 10%
PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria

Phyre2

PDB 1yx1 chain A domain 1

3D model

Region: 41 - 278
Aligned: 195
Modelled: 194
Confidence: 91.7%
Identity: 14%
Fold: TIM beta/alpha-barrel
Superfamily: Xylose isomerase-like
Family: KguE-like

Phyre2

PDB 3fkk chain A

3D model

Region: 176 - 319
Aligned: 130
Modelled: 130
Confidence: 80.6%
Identity: 13%
PDB header:lyase
Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase;
PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase

Phyre2
1

c3cixA_
2

c1r30A_
3

d1r30a_
4

c2qgqF_
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c3t7vA_
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d1olta_
7

d1tv8a_
8

c3c8fA_
9

c3rfaA_
10

c2yx0A_
11

c2a5hC_
12

c3canA_
13

c2z2uA_
14

c3ewbX_
15

c3ivuB_
16

c3eegB_
17

c3bleA_
18

c2ftpA_
19

d1nvma2
20

c2cw6B_
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d1yx1a1
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c3fkkA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3cixA_



99.9 20 PDB header:adomet binding protein
Chain: A: PDB Molecule:fefe-hydrogenase maturase;
PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate
2c1r30A_



99.9 17 PDB header:transferase
Chain: A: PDB Molecule:biotin synthase;
PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme
3d1r30a_



99.9 17 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Biotin synthase
4c2qgqF_



99.9 12 PDB header:structural genomics, unknown function
Chain: F: PDB Molecule:protein tm_1862;
PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77
5c3t7vA_



99.9 15 PDB header:transferase
Chain: A: PDB Molecule:methylornithine synthase pylb;
PDBTitle: crystal structure of methylornithine synthase (pylb)
6d1olta_



99.8 19 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:Oxygen-independent coproporphyrinogen III oxidase HemN
7d1tv8a_



99.8 13 Fold:TIM beta/alpha-barrel
Superfamily:Radical SAM enzymes
Family:MoCo biosynthesis proteins
8c3c8fA_



99.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme;
PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet
9c3rfaA_



99.6 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n;
PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine
10c2yx0A_



99.5 16 PDB header:metal binding protein
Chain: A: PDB Molecule:radical sam enzyme;
PDBTitle: crystal structure of p. horikoshii tyw1
11c2a5hC_



99.4 15 PDB header:isomerase
Chain: C: PDB Molecule:l-lysine 2,3-aminomutase;
PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate).
12c3canA_



98.8 12 PDB header:lyase activator
Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme;
PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482
13c2z2uA_



98.5 14 PDB header:metal binding protein
Chain: A: PDB Molecule:upf0026 protein mj0257;
PDBTitle: crystal structure of archaeal tyw1
14c3ewbX_



97.8 13 PDB header:transferase
Chain: X: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes
15c3ivuB_



97.7 12 PDB header:transferase
Chain: B: PDB Molecule:homocitrate synthase, mitochondrial;
PDBTitle: homocitrate synthase lys4 bound to 2-og
16c3eegB_



97.6 7 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii
17c3bleA_



97.4 13 PDB header:transferase
Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans;
PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate
18c2ftpA_



97.4 13 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa
19d1nvma2



97.4 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
20c2cw6B_



97.2 10 PDB header:lyase
Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial;
PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
21c1rr2A_



not modelled 97.0 15 PDB header:transferase
Chain: A: PDB Molecule:transcarboxylase 5s subunit;
PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid
22c2nx9B_



not modelled 96.9 12 PDB header:lyase
Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha;
PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae
23c1sr9A_



not modelled 96.9 12 PDB header:transferase
Chain: A: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of leua from mycobacterium tuberculosis
24c1nvmG_



not modelled 96.7 13 PDB header:lyase/oxidoreductase
Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase;
PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate
25c3navB_



not modelled 96.5 12 PDB header:lyase
Chain: B: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961
26c2y7eA_



not modelled 96.2 19 PDB header:lyase
Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme;
PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form)
27d1qopa_



not modelled 96.2 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
28c1ydnA_



not modelled 96.0 9 PDB header:lyase
Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase;
PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35.
29c2ekcA_



not modelled 95.9 19 PDB header:lyase
Chain: A: PDB Molecule:tryptophan synthase alpha chain;
PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5
30c3hpxB_



not modelled 95.9 14 PDB header:transferase
Chain: B: PDB Molecule:2-isopropylmalate synthase;
PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644)
31c3no5C_



not modelled 95.8 16 PDB header:structural genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution
32c3c6cA_



not modelled 95.7 14 PDB header:hydrolase
Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme;
PDBTitle: crystal structure of a putative 3-keto-5-aminohexanoate cleavage2 enzyme (reut_c6226) from ralstonia eutropha jmp134 at 1.72 a3 resolution
33c1ydoC_



not modelled 95.6 16 PDB header:lyase
Chain: C: PDB Molecule:hmg-coa lyase;
PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181.
34c3chvA_



not modelled 95.5 14 PDB header:metal binding protein
Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim
PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution
35c2zyfA_



not modelled 95.3 10 PDB header:transferase
Chain: A: PDB Molecule:homocitrate synthase;
PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate
36c3e02A_



not modelled 94.7 14 PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein duf849;
PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution
37d1rqba2



not modelled 94.4 15 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:HMGL-like
38c3b0vD_



not modelled 94.3 17 PDB header:oxidoreductase/rna
Chain: D: PDB Molecule:trna-dihydrouridine synthase;
PDBTitle: trna-dihydrouridine synthase from thermus thermophilus in complex with2 trna
39d1b5ta_



not modelled 93.8 13 Fold:TIM beta/alpha-barrel
Superfamily:FAD-linked oxidoreductase
Family:Methylenetetrahydrofolate reductase
40c3na8A_



not modelled 93.2 10 PDB header:lyase
Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase;
PDBTitle: crystal structure of a putative dihydrodipicolinate synthetase from2 pseudomonas aeruginosa
41c3dxiB_



not modelled 93.1 7 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative aldolase;
PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus
42c3khdC_



not modelled 92.9 10 PDB header:transferase
Chain: C: PDB Molecule:pyruvate kinase;
PDBTitle: crystal structure of pff1300w.
43c3ktcB_



not modelled 92.8 13 PDB header:isomerase
Chain: B: PDB Molecule:xylose isomerase;
PDBTitle: crystal structure of putative sugar isomerase (yp_050048.1) from2 erwinia carotovora atroseptica scri1043 at 1.54 a resolution
44c3e49A_



not modelled 92.6 13 PDB header:metal binding protein
Chain: A: PDB Molecule:uncharacterized protein duf849 with a tim barrel fold;
PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 with a tim barrel fold (bxe_c0966) from burkholderia xenovorans lb4003 at 1.75 a resolution
45c2vc6A_



not modelled 92.5 12 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: structure of mosa from s. meliloti with pyruvate bound
46c2ehhE_



not modelled 91.9 12 PDB header:lyase
Chain: E: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus
47d1o5ka_



not modelled 91.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
48d1yx1a1



91.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:KguE-like
49c3noeA_



not modelled 91.7 11 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from pseudomonas2 aeruginosa
50c3ggsA_



not modelled 91.6 15 PDB header:transferase
Chain: A: PDB Molecule:purine nucleoside phosphorylase;
PDBTitle: human purine nucleoside phosphorylase double mutant e201q,n243d2 complexed with 2-fluoro-2'-deoxyadenosine
51c3lotC_



not modelled 91.5 19 PDB header:structure genomics, unknown function
Chain: C: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of protein of unknown function (np_070038.1) from2 archaeoglobus fulgidus at 1.89 a resolution
52c3lciA_



not modelled 91.4 14 PDB header:lyase
Chain: A: PDB Molecule:n-acetylneuraminate lyase;
PDBTitle: the d-sialic acid aldolase mutant v251w
53c3g0sA_



not modelled 91.0 13 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2
54c3n2xB_



not modelled 90.9 12 PDB header:lyase
Chain: B: PDB Molecule:uncharacterized protein yage;
PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate
55c3daqB_



not modelled 90.8 11 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus
56c2r8wB_



not modelled 90.8 15 PDB header:lyase
Chain: B: PDB Molecule:agr_c_1641p;
PDBTitle: the crystal structure of dihydrodipicolinate synthase (atu0899) from2 agrobacterium tumefaciens str. c58
57c3labA_



not modelled 90.7 15 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative kdpg (2-keto-3-deoxy-6-phosphogluconate)
PDBTitle: crystal structure of a putative kdpg (2-keto-3-deoxy-6-2 phosphogluconate) aldolase from oleispira antarctica
58c2yxgD_



not modelled 90.7 13 PDB header:lyase
Chain: D: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihyrodipicolinate synthase (dapa)
59c2pa6A_



not modelled 90.7 14 PDB header:lyase
Chain: A: PDB Molecule:enolase;
PDBTitle: crystal structure of mj0232 from methanococcus jannaschii
60c3eb2A_



not modelled 90.6 12 PDB header:lyase
Chain: A: PDB Molecule:putative dihydrodipicolinate synthetase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 2.0a resolution
61c3lerA_



not modelled 90.5 14 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 campylobacter jejuni subsp. jejuni nctc 11168
62c3bi8A_



not modelled 90.3 10 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: structure of dihydrodipicolinate synthase from clostridium2 botulinum
63c3c52B_



not modelled 90.2 9 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase;
PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor
64c2rfgB_



not modelled 90.2 11 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution
65c2v9dB_



not modelled 90.1 12 PDB header:lyase
Chain: B: PDB Molecule:yage;
PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12
66d1f74a_



not modelled 90.1 11 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
67d3pnpa_



not modelled 89.9 18 Fold:Phosphorylase/hydrolase-like
Superfamily:Purine and uridine phosphorylases
Family:Purine and uridine phosphorylases
68c2f06B_



not modelled 89.8 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron
69d1xkya1



not modelled 89.7 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
70d1xxxa1



not modelled 89.7 16 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
71d2a6na1



not modelled 89.5 12 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
72c3fluD_



not modelled 89.4 13 PDB header:lyase
Chain: D: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis
73d3bgsa1



not modelled 89.4 16 Fold:Phosphorylase/hydrolase-like
Superfamily:Purine and uridine phosphorylases
Family:Purine and uridine phosphorylases
74d1hl2a_



not modelled 89.3 14 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
75c2fmoA_



not modelled 89.3 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate reductase;
PDBTitle: ala177val mutant of e. coli methylenetetrahydrofolate2 reductase
76c2pjuD_



not modelled 88.7 12 PDB header:transcription
Chain: D: PDB Molecule:propionate catabolism operon regulatory protein;
PDBTitle: crystal structure of propionate catabolism operon2 regulatory protein prpr
77c3q94B_



not modelled 88.4 10 PDB header:lyase
Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii;
PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor'
78c2qv5A_



not modelled 88.4 7 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein atu2773;
PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58
79c3pueA_



not modelled 88.4 11 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution
80c3si9B_



not modelled 88.3 11 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from bartonella2 henselae
81c3kwsB_



not modelled 88.1 9 PDB header:isomerase
Chain: B: PDB Molecule:putative sugar isomerase;
PDBTitle: crystal structure of putative sugar isomerase (yp_001305149.1) from2 parabacteroides distasonis atcc 8503 at 1.68 a resolution
82c3qfeB_



not modelled 87.6 14 PDB header:lyase
Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein;
PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis
83c3h5dD_



not modelled 87.6 18 PDB header:lyase
Chain: D: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: dihydrodipicolinate synthase from drug-resistant streptococcus2 pneumoniae
84c3g8rA_



not modelled 87.5 12 PDB header:biosynthetic protein
Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e;
PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472
85d2pjua1



not modelled 87.1 12 Fold:Chelatase-like
Superfamily:PrpR receptor domain-like
Family:PrpR receptor domain-like
86d1mxsa_



not modelled 86.9 20 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
87d1ps9a1



not modelled 86.6 15 Fold:TIM beta/alpha-barrel
Superfamily:FMN-linked oxidoreductases
Family:FMN-linked oxidoreductases
88d1pkla2



not modelled 86.6 14 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
89c3e96B_



not modelled 86.5 13 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 bacillus clausii
90d1liua2



not modelled 86.2 13 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Pyruvate kinase
91c3cprB_



not modelled 86.0 15 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthetase;
PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution
92c3otrC_



not modelled 85.9 13 PDB header:lyase
Chain: C: PDB Molecule:enolase;
PDBTitle: 2.75 angstrom crystal structure of enolase 1 from toxoplasma gondii
93d1xcfa_



not modelled 85.3 17 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Tryptophan biosynthesis enzymes
94d1k77a_



not modelled 84.8 12 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:Hypothetical protein YgbM (EC1530)
95d1muma_



not modelled 84.8 17 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like
96c2r94B_



not modelled 84.2 13 PDB header:lyase
Chain: B: PDB Molecule:2-keto-3-deoxy-(6-phospho-)gluconate aldolase;
PDBTitle: crystal structure of kd(p)ga from t.tenax
97d1oy0a_



not modelled 83.8 16 Fold:TIM beta/alpha-barrel
Superfamily:Phosphoenolpyruvate/pyruvate domain
Family:Ketopantoate hydroxymethyltransferase PanB
98c3d0cB_



not modelled 83.5 15 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 oceanobacillus iheyensis at 1.9 a resolution
99d1wbha1



not modelled 83.4 19 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
100c3s5oA_



not modelled 83.1 17 PDB header:lyase
Chain: A: PDB Molecule:4-hydroxy-2-oxoglutarate aldolase, mitochondrial;
PDBTitle: crystal structure of human 4-hydroxy-2-oxoglutarate aldolase bound to2 pyruvate
101d1vhca_



not modelled 82.6 20 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class I aldolase
102d1vp8a_



not modelled 82.1 15 Fold:Pyruvate kinase C-terminal domain-like
Superfamily:PK C-terminal domain-like
Family:MTH1675-like
103d1thfd_



not modelled 81.9 14 Fold:TIM beta/alpha-barrel
Superfamily:Ribulose-phoshate binding barrel
Family:Histidine biosynthesis enzymes
104c3kw2A_



not modelled 81.5 10 PDB header:transferase
Chain: A: PDB Molecule:probable r-rna methyltransferase;
PDBTitle: crystal structure of probable rrna-methyltransferase from2 porphyromonas gingivalis
105c3fkkA_



80.6 13 PDB header:lyase
Chain: A: PDB Molecule:l-2-keto-3-deoxyarabonate dehydratase;
PDBTitle: structure of l-2-keto-3-deoxyarabonate dehydratase
106c3ct7E_



not modelled 80.6 10 PDB header:isomerase
Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase;
PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12
107d1i60a_



not modelled 80.3 11 Fold:TIM beta/alpha-barrel
Superfamily:Xylose isomerase-like
Family:IolI-like
108c3bg3B_



not modelled 79.7 16 PDB header:ligase
Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial;
PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus)
109d1gvfa_



not modelled 79.5 8 Fold:TIM beta/alpha-barrel
Superfamily:Aldolase
Family:Class II FBP aldolase
110c3aamA_



not modelled 79.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:endonuclease iv;
PDBTitle: crystal structure of endonuclease iv from thermus thermophilus hb8
111c3dz1A_



not modelled 78.6 13 PDB header:lyase
Chain: A: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution
112c1zlpA_



not modelled 78.5 18 PDB header:lyase
Chain: A: PDB Molecule:petal death protein;
PDBTitle: petal death protein psr132 with cysteine-linked glutaraldehyde forming2 a thiohemiacetal adduct
113c2z1kA_



not modelled 78.4 23 PDB header:hydrolase
Chain: A: PDB Molecule:(neo)pullulanase;
PDBTitle: crystal structure of ttha1563 from thermus thermophilus hb8
114d2akza1



not modelled 77.9 15 Fold:TIM beta/alpha-barrel
Superfamily:Enolase C-terminal domain-like
Family:Enolase
115c1jpkA_



not modelled 77.8 12 PDB header:lyase
Chain: A: PDB Molecule:uroporphyrinogen decarboxylase;
PDBTitle: gly156asp mutant of human urod, human uroporphyrinogen iii2 decarboxylase
116c3dx5A_



not modelled 77.7 11 PDB header:lyase
Chain: A: PDB Molecule:uncharacterized protein asbf;
PDBTitle: crystal structure of the probable 3-dhs dehydratase asbf involved in2 the petrobactin synthesis from bacillus anthracis
117c3b4uB_



not modelled 77.2 15 PDB header:lyase
Chain: B: PDB Molecule:dihydrodipicolinate synthase;
PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58
118d1ktba2



not modelled 77.2 14 Fold:TIM beta/alpha-barrel
Superfamily:(Trans)glycosidases
Family:Amylase, catalytic domain
119c1xuzA_



not modelled 76.4 20 PDB header:biosynthetic protein
Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac;
PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol
120c1uasA_



not modelled 76.2 10 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-galactosidase;
PDBTitle: crystal structure of rice alpha-galactosidase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0