Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	P	F	R	S	N	N	P	I	T	R	D	E	L	L	S	R	F	F	P	Q	Y	H	P	V	T	T	F	N	S	G	L	S	G	G	S	F	L	I	E	H	Q	G	Q	R	F	V	V	R	Q	P	H	D	P	D	A	P	Q	S	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																		?																															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		F	L	R	Q	Y	R	A	L	S	Q	L	P	A	C	I	A	P	K	P	H	L	Y	L	R	D	W	M	V	V	D	Y	L	P	G	A	V	K	T	Y	L	P	D	T	N	E	L	A	G	L	L	Y	Y	L	H	Q	Q	P	R	F	G
Secondary structure
SS confidence
Disorder																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		W	R	I	T	L	L	P	L	L	E	L	Y	W	Q	Q	S	D	P	A	R	R	T	V	G	W	L	R	M	L	K	R	L	R	K	A	R	E	P	R	P	L	R	L	S	P	L	H	M	D	V	H	A	G	N	L	V	H	S	A	S
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	L	K	L	I	D	W	E	Y	A	G	D	G	D	I	A	L	E	L	A	A	V	W	V	E	N	T	E	Q	H	R	Q	L	V	N	D	Y	A	T	R	A	K	I	Y	P	A	Q	L	W	R	Q	V	R	R	W	F	P	W	L	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.
Sequence		M	L	K	A	G	W	F	E	Y	R	W	R	Q	T	G	D	Q	Q	F	I	R	L	A	D	D	T	W	R	Q	L	L	I	K	Q
Secondary structure
SS confidence
Disorder																																	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ig7 chain A Region: 16 - 269 Aligned: 252 Modelled: 254 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:choline/ethanolamine kinase; PDBTitle: crystal structure of human choline kinase b Phyre2 PDB 1nw1 chain A Region: 16 - 271 Aligned: 254 Modelled: 256 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:choline kinase (49.2 kd); PDBTitle: crystal structure of choline kinase Phyre2 PDB 1nw1 chain A Region: 16 - 271 Aligned: 254 Modelled: 256 Confidence: 100.0% Identity: 18% Fold: Protein kinase-like (PK-like) Superfamily: Protein kinase-like (PK-like) Family: Choline kinase Phyre2 PDB 3c5i chain D Region: 7 - 269 Aligned: 261 Modelled: 263 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:choline kinase; PDBTitle: crystal structure of plasmodium knowlesi choline kinase, pkh_134520 Phyre2 PDB 3f2r chain A Region: 5 - 271 Aligned: 267 Modelled: 267 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: A: PDB Molecule:choline kinase alpha; PDBTitle: crystal structure of human choline kinase alpha in complex2 with hemicholinium-3 Phyre2 PDB 3mes chain B Region: 13 - 271 Aligned: 253 Modelled: 253 Confidence: 100.0% Identity: 18% PDB header:transferase Chain: B: PDB Molecule:choline kinase; PDBTitle: crystal structure of choline kinase from cryptosporidium2 parvum iowa ii, cgd3_2030 Phyre2 PDB 3dxq chain B Region: 11 - 270 Aligned: 246 Modelled: 260 Confidence: 100.0% Identity: 21% PDB header:transferase Chain: B: PDB Molecule:choline/ethanolamine kinase family protein; PDBTitle: crystal structure of choline/ethanolamine kinase family protein2 (np_106042.1) from mesorhizobium loti at 2.55 a resolution Phyre2 PDB 2qg7 chain A Region: 21 - 269 Aligned: 244 Modelled: 249 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:ethanolamine kinase pv091845; PDBTitle: plasmodium vivax ethanolamine kinase pv091845 Phyre2 PDB 3ovc chain A Region: 12 - 271 Aligned: 251 Modelled: 260 Confidence: 100.0% Identity: 16% PDB header:transferase/antibiotic Chain: A: PDB Molecule:hygromycin-b 4-o-kinase; PDBTitle: crystal structure of aminoglycoside phosphotransferase aph(4)-ia Phyre2 PDB 3jr1 chain A Region: 12 - 273 Aligned: 253 Modelled: 262 Confidence: 100.0% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase2 (yp_719053.1) from haemophilus somnus 129pt at 2.32 a3 resolution Phyre2 PDB 2ppq chain A domain 1 Region: 8 - 256 Aligned: 244 Modelled: 249 Confidence: 100.0% Identity: 16% Fold: Protein kinase-like (PK-like) Superfamily: Protein kinase-like (PK-like) Family: APH phosphotransferases Phyre2 PDB 1zyl chain A domain 1 Region: 9 - 261 Aligned: 247 Modelled: 253 Confidence: 100.0% Identity: 18% Fold: Protein kinase-like (PK-like) Superfamily: Protein kinase-like (PK-like) Family: APH phosphotransferases Phyre2 PDB 3lzh chain A Region: 12 - 268 Aligned: 249 Modelled: 257 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:aph(2")-id/aph(2")-iva; PDBTitle: crystal structure of aminoglycoside phosphotransferase aph(2")-2 id/aph(2")-iva Phyre2 PDB 3ham chain A Region: 12 - 273 Aligned: 254 Modelled: 262 Confidence: 100.0% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:aminoglycoside phosphotransferase; PDBTitle: structure of the gentamicin-aph(2")-iia complex Phyre2 PDB 3dxp chain A Region: 12 - 270 Aligned: 252 Modelled: 258 Confidence: 100.0% Identity: 17% PDB header:transferase Chain: A: PDB Molecule:putative acyl-coa dehydrogenase; PDBTitle: crystal structure of a putative aminoglycoside phosphotransferase2 (reut_a1007) from ralstonia eutropha jmp134 at 2.32 a resolution Phyre2 PDB 3f7w chain A Region: 11 - 254 Aligned: 241 Modelled: 244 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase (yp_290396.1) from2 thermobifida fusca yx-er1 at 1.85 a resolution Phyre2 PDB 2pul chain A domain 1 Region: 7 - 246 Aligned: 229 Modelled: 233 Confidence: 99.9% Identity: 17% Fold: Protein kinase-like (PK-like) Superfamily: Protein kinase-like (PK-like) Family: APH phosphotransferases Phyre2 PDB 3csv chain A Region: 10 - 270 Aligned: 253 Modelled: 261 Confidence: 99.9% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:aminoglycoside phosphotransferase; PDBTitle: crystal structure of a putative aminoglycoside phosphotransferase2 (yp_614837.1) from silicibacter sp. tm1040 at 2.15 a resolution Phyre2 PDB 3att chain A Region: 12 - 274 Aligned: 259 Modelled: 263 Confidence: 99.9% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of rv3168 with atp Phyre2 PDB 1j7l chain A Region: 9 - 241 Aligned: 228 Modelled: 233 Confidence: 99.9% Identity: 13% Fold: Protein kinase-like (PK-like) Superfamily: Protein kinase-like (PK-like) Family: APH phosphotransferases Phyre2 1 c2ig7A_ 2 c1nw1A_ 3 d1nw1a_ 4 c3c5iD_ 5 c3f2rA_ 6 c3mesB_ 7 c3dxqB_ 8 c2qg7A_ 9 c3ovcA_ 10 c3jr1A_ 11 d2ppqa1 12 d1zyla1 13 c3lzhA_ 14 c3hamA_ 15 c3dxpA_ 16 c3f7wA_ 17 d2pula1 18 c3csvA_ 19 c3attA_ 20 d1j7la_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ig7A_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:choline/ethanolamine kinase; PDBTitle: crystal structure of human choline kinase b 2 c1nw1A_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:choline kinase (49.2 kd); PDBTitle: crystal structure of choline kinase 3 d1nw1a_ 100.0 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Choline kinase 4 c3c5iD_ 100.0 17 PDB header:transferase Chain: D: PDB Molecule:choline kinase; PDBTitle: crystal structure of plasmodium knowlesi choline kinase, pkh_134520 5 c3f2rA_ 100.0 18 PDB header:transferase Chain: A: PDB Molecule:choline kinase alpha; PDBTitle: crystal structure of human choline kinase alpha in complex2 with hemicholinium-3 6 c3mesB_ 100.0 18 PDB header:transferase Chain: B: PDB Molecule:choline kinase; PDBTitle: crystal structure of choline kinase from cryptosporidium2 parvum iowa ii, cgd3_2030 7 c3dxqB_ 100.0 21 PDB header:transferase Chain: B: PDB Molecule:choline/ethanolamine kinase family protein; PDBTitle: crystal structure of choline/ethanolamine kinase family protein2 (np_106042.1) from mesorhizobium loti at 2.55 a resolution 8 c2qg7A_ 100.0 15 PDB header:transferase Chain: A: PDB Molecule:ethanolamine kinase pv091845; PDBTitle: plasmodium vivax ethanolamine kinase pv091845 9 c3ovcA_ 100.0 16 PDB header:transferase/antibiotic Chain: A: PDB Molecule:hygromycin-b 4-o-kinase; PDBTitle: crystal structure of aminoglycoside phosphotransferase aph(4)-ia 10 c3jr1A_ 100.0 13 PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase2 (yp_719053.1) from haemophilus somnus 129pt at 2.32 a3 resolution 11 d2ppqa1 100.0 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:APH phosphotransferases 12 d1zyla1 100.0 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:APH phosphotransferases 13 c3lzhA_ 100.0 14 PDB header:transferase Chain: A: PDB Molecule:aph(2")-id/aph(2")-iva; PDBTitle: crystal structure of aminoglycoside phosphotransferase aph(2")-2 id/aph(2")-iva 14 c3hamA_ 100.0 15 PDB header:transferase Chain: A: PDB Molecule:aminoglycoside phosphotransferase; PDBTitle: structure of the gentamicin-aph(2")-iia complex 15 c3dxpA_ 100.0 17 PDB header:transferase Chain: A: PDB Molecule:putative acyl-coa dehydrogenase; PDBTitle: crystal structure of a putative aminoglycoside phosphotransferase2 (reut_a1007) from ralstonia eutropha jmp134 at 2.32 a resolution 16 c3f7wA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:putative fructosamine-3-kinase; PDBTitle: crystal structure of putative fructosamine-3-kinase (yp_290396.1) from2 thermobifida fusca yx-er1 at 1.85 a resolution 17 d2pula1 99.9 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:APH phosphotransferases 18 c3csvA_ 99.9 15 PDB header:transferase Chain: A: PDB Molecule:aminoglycoside phosphotransferase; PDBTitle: crystal structure of a putative aminoglycoside phosphotransferase2 (yp_614837.1) from silicibacter sp. tm1040 at 2.15 a resolution 19 c3attA_ 99.9 16 PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of rv3168 with atp 20 d1j7la_ 99.9 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:APH phosphotransferases 21 c2pywA_ not modelled 99.9 15 PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: structure of a. thaliana 5-methylthioribose kinase in complex with adp2 and mtr 22 d1nd4a_ not modelled 99.9 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:APH phosphotransferases 23 c3i0oA_ not modelled 99.9 11 PDB header:transferase Chain: A: PDB Molecule:spectinomycin phosphotransferase; PDBTitle: crystal structure of spectinomycin phosphotransferase,2 aph(9)-ia, in complex with adp and spectinomcyin 24 c3r78B_ not modelled 99.9 17 PDB header:transferase Chain: B: PDB Molecule:aminoglycoside 3'-phosphotransferase apha1-iab; PDBTitle: crystal structure of the aminoglycoside phosphotransferase aph(3')-ia,2 atp-bound 25 c2q83A_ not modelled 99.8 17 PDB header:transferase Chain: A: PDB Molecule:ytaa protein; PDBTitle: crystal structure of ytaa (2635576) from bacillus subtilis at 2.50 a2 resolution 26 c3en9B_ not modelled 99.2 17 PDB header:hydrolase Chain: B: PDB Molecule:o-sialoglycoprotein endopeptidase/protein kinase; PDBTitle: structure of the methanococcus jannaschii kae1-bud32 fusion2 protein 27 c2pziA_ not modelled 98.9 21 PDB header:transferase Chain: A: PDB Molecule:probable serine/threonine-protein kinase pkng; PDBTitle: crystal structure of protein kinase pkng from mycobacterium2 tuberculosis in complex with tetrahydrobenzothiophene ax20017 28 c1tqmA_ not modelled 98.9 15 PDB header:ribosome Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of a. fulgidus rio2 serine protein kinase bound to2 amppnp 29 d1zara2 not modelled 98.7 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:RIO1-like kinases 30 c3qa8A_ not modelled 98.3 29 PDB header:immune system, signaling protein Chain: A: PDB Molecule:mgc80376 protein; PDBTitle: crystal structure of inhibitor of kappa b kinase beta 31 c1zp9A_ not modelled 98.1 19 PDB header:transferase Chain: A: PDB Molecule:rio1 kinase; PDBTitle: crystal structure of full-legnth a.fulgidus rio1 serine kinase bound2 to atp and mn2+ ions. 32 c2fo0A_ not modelled 97.9 10 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase abl1 (1b isoform); PDBTitle: organization of the sh3-sh2 unit in active and inactive forms of the2 c-abl tyrosine kinase 33 c2vwiC_ not modelled 97.9 22 PDB header:transferase Chain: C: PDB Molecule:serine/threonine-protein kinase osr1; PDBTitle: structure of the osr1 kinase, a hypertension drug target 34 c3ckxA_ not modelled 97.8 18 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 24; PDBTitle: crystal structure of sterile 20-like kinase 3 (mst3, stk24)2 in complex with staurosporine 35 c1oplA_ not modelled 97.7 16 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase; PDBTitle: structural basis for the auto-inhibition of c-abl tyrosine2 kinase 36 c3dzoA_ not modelled 97.7 18 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase domain; PDBTitle: crystal structure of a rhoptry kinase from toxoplasma gondii 37 c3e7eA_ not modelled 97.7 18 PDB header:transferase Chain: A: PDB Molecule:mitotic checkpoint serine/threonine-protein kinase bub1; PDBTitle: structure and substrate recruitment of the human spindle checkpoint2 kinase bub 38 c1k9aB_ not modelled 97.7 24 PDB header:transferase Chain: B: PDB Molecule:carboxyl-terminal src kinase; PDBTitle: crystal structure analysis of full-length carboxyl-terminal2 src kinase at 2.5 a resolution 39 c2j0kB_ not modelled 97.7 19 PDB header:transferase Chain: B: PDB Molecule:focal adhesion kinase 1; PDBTitle: crystal structure of a fragment of focal adhesion kinase2 containing the ferm and kinase domains. 40 c3pfqA_ not modelled 97.7 20 PDB header:transferase Chain: A: PDB Molecule:protein kinase c beta type; PDBTitle: crystal structure and allosteric activation of protein kinase c beta2 ii 41 c2vuwA_ not modelled 97.6 17 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase haspin; PDBTitle: structure of human haspin kinase domain 42 c3q60A_ not modelled 97.6 28 PDB header:transferase Chain: A: PDB Molecule:rop5b; PDBTitle: crystal structure of virulent allele rop5b pseudokinase domain bound2 to atp 43 d1qcfa3 not modelled 97.6 21 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 44 c2ozoA_ not modelled 97.5 16 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase zap-70; PDBTitle: autoinhibited intact human zap-70 45 c2c0iA_ not modelled 97.5 16 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase hck; PDBTitle: src family kinase hck with bound inhibitor a-420983 46 c2h8hA_ not modelled 97.5 14 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: src kinase in complex with a quinazoline inhibitor 47 c1y57A_ not modelled 97.5 15 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase src; PDBTitle: structure of unphosphorylated c-src in complex with an inhibitor 48 d1opja_ not modelled 97.4 11 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 49 c3c4yA_ not modelled 97.4 12 PDB header:transferase Chain: A: PDB Molecule:rhodopsin kinase; PDBTitle: crystal structure of apo form of g protein coupled receptor kinase 12 at 7.51a 50 c2a1aB_ not modelled 97.4 22 PDB header:protein synthesis/transferase Chain: B: PDB Molecule:interferon-induced, double-stranded rna-activated protein PDBTitle: pkr kinase domain-eif2alpha complex 51 c3p23B_ not modelled 97.4 15 PDB header:hydrolase, transferase Chain: B: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the human kinase and rnase domains in complex2 with adp 52 c3soaA_ not modelled 97.3 18 PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase type ii subunit PDBTitle: full-length human camkii 53 c2acxB_ not modelled 97.3 16 PDB header:transferase Chain: B: PDB Molecule:g protein-coupled receptor kinase 6; PDBTitle: crystal structure of g protein coupled receptor kinase 6 bound to2 amppnp 54 c2bujA_ not modelled 97.2 16 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase 16; PDBTitle: crystal structure of the human serine-threonine kinase 162 in complex with staurosporine 55 c1ym7C_ not modelled 97.1 18 PDB header:transferase Chain: C: PDB Molecule:beta-adrenergic receptor kinase 1; PDBTitle: g protein-coupled receptor kinase 2 (grk2) 56 c3d9vA_ not modelled 97.0 20 PDB header:transferase Chain: A: PDB Molecule:rho-associated protein kinase 1; PDBTitle: crystal structure of rock i bound to h-1152p a di-2 methylated variant of fasudil 57 d1iasa_ not modelled 97.0 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 58 c3dfaA_ not modelled 97.0 22 PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase cgd3_920; PDBTitle: crystal structure of kinase domain of calcium-dependent protein kinase2 cgd3_920 from cryptosporidium parvum 59 d1qpca_ not modelled 97.0 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 60 c1koaA_ not modelled 97.0 21 PDB header:kinase Chain: A: PDB Molecule:twitchin; PDBTitle: twitchin kinase fragment (c.elegans), autoregulated protein2 kinase and immunoglobulin domains 61 d1fmka3 not modelled 96.8 13 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 62 c3fbvL_ not modelled 96.8 18 PDB header:transferase, hydrolase Chain: L: PDB Molecule:serine/threonine-protein kinase/endoribonuclease ire1; PDBTitle: crystal structure of the oligomer formed by the kinase-ribonuclease2 domain of ire1 63 c2y7jB_ not modelled 96.8 22 PDB header:transferase Chain: B: PDB Molecule:phosphorylase b kinase gamma catalytic chain, PDBTitle: structure of human phosphorylase kinase, gamma 2 64 d1phka_ not modelled 96.8 21 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 65 c2c30A_ not modelled 96.7 19 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase pak 6; PDBTitle: crystal structure of the human p21-activated kinase 6 66 c3cokB_ not modelled 96.6 13 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase plk4; PDBTitle: crystal structure of plk4 kinase 67 c3q5iA_ not modelled 96.6 17 PDB header:transferase Chain: A: PDB Molecule:protein kinase; PDBTitle: crystal structure of pbanka_031420 68 c3kvwA_ not modelled 96.6 19 PDB header:transferase Chain: A: PDB Molecule:dual specificity tyrosine-phosphorylation-regulated kinase PDBTitle: crystal structure of dual-specificity tyrosine phosphorylation2 regulated kinase 2 (dyrk2) in complex with an indirubin ligand 69 c2j51A_ not modelled 96.6 13 PDB header:transferase Chain: A: PDB Molecule:ste20-like serine/threonine-protein kinase; PDBTitle: crystal structure of human ste20-like kinase bound to 5-2 amino-3-((4-(aminosulfonyl)phenyl)amino)-n-(2,6-3 difluorophenyl)-1h-1,2,4-triazole-1-carbothioamide 70 c2zv2A_ not modelled 96.6 24 PDB header:transferase/transferase inhibitor Chain: A: PDB Molecule:calcium/calmodulin-dependent protein kinase kinase 2; PDBTitle: crystal structure of human calcium/calmodulin-dependent protein kinase2 kinase 2, beta, camkk2 kinase domain in complex with sto-609 71 c2jiiA_ not modelled 96.5 19 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase vrk3 molecule: vaccinia PDBTitle: structure of vaccinia related kinase 3 72 d1u59a_ not modelled 96.5 16 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 73 c3lltA_ not modelled 96.5 16 PDB header:transferase Chain: A: PDB Molecule:serine/threonine kinase-1, pflammer; PDBTitle: crystal structure of pf14_0431, kinase domain. 74 d2j4za1 not modelled 96.5 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 75 c2wu6A_ not modelled 96.5 15 PDB header:transferase Chain: A: PDB Molecule:dual specificity protein kinase clk3; PDBTitle: crystal structure of the human clk3 in complex with dki 76 c2cgvA_ not modelled 96.5 17 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: identification of chemically diverse chk1 inhibitors by2 receptor-based virtual screening 77 c2wtkC_ not modelled 96.5 16 PDB header:transferase/metal-binding protein Chain: C: PDB Molecule:serine/threonine-protein kinase 11; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 78 c2qluA_ not modelled 96.5 15 PDB header:transferase Chain: A: PDB Molecule:activin receptor type iib; PDBTitle: crystal structure of activin receptor type ii kinase domain2 from human 79 c1mruB_ not modelled 96.4 14 PDB header:transferase Chain: B: PDB Molecule:probable serine/threonine-protein kinase pknb; PDBTitle: intracellular ser/thr protein kinase domain of2 mycobacterium tuberculosis pknb. 80 d1yhwa1 not modelled 96.4 24 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 81 c2bmcD_ not modelled 96.4 17 PDB header:transferase Chain: D: PDB Molecule:serine threonine-protein kinase 6; PDBTitle: aurora-2 t287d t288d complexed with pha-680632 82 c2wqmA_ not modelled 96.4 13 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase nek7; PDBTitle: structure of apo human nek7 83 c2clqA_ not modelled 96.3 18 PDB header:transferase Chain: A: PDB Molecule:mitogen-activated protein kinase kinase kinase 5; PDBTitle: structure of mitogen-activated protein kinase kinase kinase2 5 84 c3byvA_ not modelled 96.3 23 PDB header:transferase Chain: A: PDB Molecule:rhoptry kinase; PDBTitle: crystal structure of toxoplasma gondii specific rhoptry2 antigen kinase domain 85 c2ivsA_ not modelled 96.2 16 PDB header:transferase Chain: A: PDB Molecule:proto-oncogene tyrosine-protein kinase receptor PDBTitle: crystal structure of non-phosphorylated ret tyrosine kinase2 domain 86 d1o6ya_ not modelled 96.2 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 87 c2wtkB_ not modelled 96.1 13 PDB header:transferase/metal-binding protein Chain: B: PDB Molecule:ste20-related kinase adapter protein alpha; PDBTitle: structure of the heterotrimeric lkb1-stradalpha-mo25alpha2 complex 88 c2vd5A_ not modelled 96.1 19 PDB header:transferase Chain: A: PDB Molecule:dmpk protein; PDBTitle: structure of human myotonic dystrophy protein kinase in2 complex with the bisindoylmaleide inhibitor bim viii 89 c2qg5D_ not modelled 96.1 17 PDB header:transferase Chain: D: PDB Molecule:calcium/calmodulin-dependent protein kinase; PDBTitle: cryptosporidium parvum calcium dependent protein kinase cgd7_1840 90 c3is5E_ not modelled 96.1 17 PDB header:transferase Chain: E: PDB Molecule:calcium-dependent protein kinase; PDBTitle: crystal structure of cdpk kinase domain from toxoplasma gondii,2 tgme49_018720 91 d1jksa_ not modelled 96.1 18 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 92 c3g0eA_ not modelled 96.0 20 PDB header:transferase Chain: A: PDB Molecule:mast/stem cell growth factor receptor; PDBTitle: kit kinase domain in complex with sunitinib 93 d1nvra_ not modelled 95.9 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 94 c3zzwA_ not modelled 95.9 12 PDB header:transferase Chain: A: PDB Molecule:tyrosine-protein kinase transmembrane receptor ror2; PDBTitle: crystal structure of the kinase domain of ror2 95 d1k2pa_ not modelled 95.8 12 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 96 c2a27B_ not modelled 95.8 19 PDB header:transferase Chain: B: PDB Molecule:death-associated protein kinase 2; PDBTitle: human drp-1 kinase, w305s s308a d40 mutant, crystal form with 82 monomers in the asymmetric unit 97 d1sm2a_ not modelled 95.7 11 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 98 c3lijA_ not modelled 95.6 19 PDB header:transferase Chain: A: PDB Molecule:calcium/calmodulin dependent protein kinase with PDBTitle: crystal structure of full length cpcdpk3 (cgd5_820) in2 complex with ca2+ and amppnp 99 c2r7bA_ not modelled 95.6 21 PDB header:signaling protein, transferase Chain: A: PDB Molecule:phosphoinositide-dependent protein kinase 1; PDBTitle: crystal structure of the phosphoinositide-dependent kinase-2 1 (pdk-1)catalytic domain bound to a dibenzonaphthyridine3 inhibitor 100 c3comB_ not modelled 95.6 25 PDB header:transferase Chain: B: PDB Molecule:serine/threonine-protein kinase 4; PDBTitle: crystal structure of mst1 kinase 101 c2in6A_ not modelled 95.4 20 PDB header:transferase Chain: A: PDB Molecule:wee1-like protein kinase; PDBTitle: wee1 kinase complex with inhibitor pd311839 102 d2jfla1 not modelled 95.3 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 103 c3dpkA_ not modelled 95.3 22 PDB header:transferase Chain: A: PDB Molecule:macrophage colony-stimulating factor 1 receptor; PDBTitle: cfms tyrosine kinase in complex with a pyridopyrimidinone2 inhibitor 104 c2x7fA_ not modelled 95.3 14 PDB header:transferase Chain: A: PDB Molecule:traf2 and nck-interacting protein kinase; PDBTitle: crystal structure of the kinase domain of human traf2- and2 nck-interacting kinase with wee1chk1 inhibitor 105 c3h9rA_ not modelled 95.3 16 PDB header:isomerase/protein kinase Chain: A: PDB Molecule:activin receptor type-1; PDBTitle: crystal structure of the kinase domain of type i activin receptor2 (acvr1) in complex with fkbp12 and dorsomorphin 106 c3begA_ not modelled 95.2 11 PDB header:transferase/splicing Chain: A: PDB Molecule:serine/threonine-protein kinase srpk1; PDBTitle: crystal structure of sr protein kinase 1 complexed to its substrate2 asf/sf2 107 c1lufA_ not modelled 95.1 15 PDB header:transferase Chain: A: PDB Molecule:muscle-specific tyrosine kinase receptor musk; PDBTitle: crystal structure of the musk tyrosine kinase: insights2 into receptor autoregulation 108 d1lufa_ not modelled 95.1 15 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 109 d1ckia_ not modelled 95.0 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 110 c2hakH_ not modelled 95.0 14 PDB header:signaling protein,transferase Chain: H: PDB Molecule:serine/threonine-protein kinase mark1; PDBTitle: catalytic and ubiqutin-associated domains of mark1/par-1 111 d2psqa1 not modelled 95.0 14 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 112 c2psqA_ not modelled 95.0 14 PDB header:transferase Chain: A: PDB Molecule:fibroblast growth factor receptor 2; PDBTitle: crystal structure of unphosphorylated unactivated wild type2 fgf receptor 2 (fgfr2) kinase domain 113 c3rgfA_ not modelled 95.0 16 PDB header:transferase,transcription Chain: A: PDB Molecule:cyclin-dependent kinase 8; PDBTitle: crystal structure of human cdk8/cycc 114 c2x4fA_ not modelled 95.0 15 PDB header:transferase Chain: A: PDB Molecule:myosin light chain kinase family member 4; PDBTitle: the crystal structure of the human myosin light chain2 kinase loc340156. 115 c2h6dA_ not modelled 94.9 21 PDB header:signaling protein,transferase Chain: A: PDB Molecule:5'-amp-activated protein kinase catalytic subunit PDBTitle: protein kinase domain of the human 5'-amp-activated protein2 kinase catalytic subunit alpha-2 (ampk alpha-2 chain) 116 c2qhnA_ not modelled 94.8 16 PDB header:transferase Chain: A: PDB Molecule:serine/threonine-protein kinase chk1; PDBTitle: crystal structure of chek1 in complex with inhibitor 1a 117 c3hztA_ not modelled 94.7 21 PDB header:transferase Chain: A: PDB Molecule:calcium-dependent protein kinase 3; PDBTitle: crystal structure of toxoplasma gondii cdpk3, tgme49_105860 118 c2c47D_ not modelled 94.7 24 PDB header:transferase Chain: D: PDB Molecule:casein kinase 1 gamma 2 isoform; PDBTitle: structure of casein kinase 1 gamma 2 119 d1koaa2 not modelled 94.7 17 Fold:Protein kinase-like (PK-like) Superfamily:Protein kinase-like (PK-like) Family:Protein kinases, catalytic subunit 120 c2chlA_ not modelled 94.6 22 PDB header:transferase Chain: A: PDB Molecule:casein kinase i isoform gamma-3; PDBTitle: structure of casein kinase 1 gamma 3

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0