Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0A8M3
DateThu Jan 5 11:08:11 GMT 2012
Unique Job ID21bd3ef6b59ac1d9

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1qf6A_
Top template information
PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna
Confidence and coverage
Confidence:100.0% Coverage:100%
641 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSII
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Disorder  ??


??




















































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   .........70.........80.........90.........100.........110.........120
Sequence  TAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEAL
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   .........130.........140.........150.........160.........170.........180
Sequence  EKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVD
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?










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   .........190.........200.........210.........220.........230.........240
Sequence  MCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAA
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?

???
















????????
???
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   .........250.........260.........270.........280.........290.........300
Sequence  KRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMD
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Disorder  ??























































??
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   .........310.........320.........330.........340.........350.........360
Sequence  RVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGS
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?

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   .........370.........380.........390.........400.........410.........420
Sequence  CHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKL
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   .........430.........440.........450.........460.........470.........480
Sequence  STRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQC
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?????



















































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   .........490.........500.........510.........520.........530.........540
Sequence  GTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPV
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   .........550.........560.........570.........580.........590.........600
Sequence  QVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKE
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   .........610.........620.........630.........640..
Sequence  VESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
Secondary structure 









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?

??














??


???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1qf6 chain A

3D model

Region: 2 - 642
Aligned: 641
Modelled: 641
Confidence: 100.0%
Identity: 100%
PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna

Phyre2

PDB 1nyq chain A

3D model

Region: 2 - 638
Aligned: 634
Modelled: 637
Confidence: 100.0%
Identity: 44%
PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase 1;
PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate

Phyre2

PDB 3a32 chain A

3D model

Region: 226 - 636
Aligned: 408
Modelled: 411
Confidence: 100.0%
Identity: 30%
PDB header:ligase
Chain: A: PDB Molecule:probable threonyl-trna synthetase 1;
PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix

Phyre2

PDB 1fyf chain B

3D model

Region: 242 - 642
Aligned: 401
Modelled: 401
Confidence: 100.0%
Identity: 100%
PDB header:ligase
Chain: B: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog

Phyre2

PDB 2i4l chain C

3D model

Region: 238 - 628
Aligned: 385
Modelled: 391
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: C: PDB Molecule:proline-trna ligase;
PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase

Phyre2

PDB 1nyr chain A domain 4

3D model

Region: 243 - 525
Aligned: 283
Modelled: 283
Confidence: 100.0%
Identity: 41%
Fold: Class II aaRS and biotin synthetases
Superfamily: Class II aaRS and biotin synthetases
Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

Phyre2

PDB 2j3m chain A

3D model

Region: 255 - 632
Aligned: 374
Modelled: 378
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol

Phyre2

PDB 1qf6 chain A domain 4

3D model

Region: 242 - 532
Aligned: 291
Modelled: 291
Confidence: 100.0%
Identity: 100%
Fold: Class II aaRS and biotin synthetases
Superfamily: Class II aaRS and biotin synthetases
Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

Phyre2

PDB 1ggm chain B

3D model

Region: 255 - 633
Aligned: 365
Modelled: 379
Confidence: 100.0%
Identity: 19%
PDB header:ligase
Chain: B: PDB Molecule:protein (glycyl-trna synthetase);
PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate

Phyre2

PDB 3ial chain B

3D model

Region: 244 - 642
Aligned: 363
Modelled: 369
Confidence: 100.0%
Identity: 21%
PDB header:ligase
Chain: B: PDB Molecule:prolyl-trna synthetase;
PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate

Phyre2

PDB 1ati chain A

3D model

Region: 246 - 633
Aligned: 374
Modelled: 387
Confidence: 100.0%
Identity: 18%
PDB header:protein biosynthesis
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus

Phyre2

PDB 1nj8 chain C

3D model

Region: 245 - 641
Aligned: 359
Modelled: 367
Confidence: 100.0%
Identity: 21%
PDB header:ligase
Chain: C: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii

Phyre2

PDB 1h4t chain D

3D model

Region: 220 - 641
Aligned: 366
Modelled: 379
Confidence: 100.0%
Identity: 23%
PDB header:aminoacyl-trna synthetase
Chain: D: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline

Phyre2

PDB 1nj2 chain A

3D model

Region: 246 - 641
Aligned: 353
Modelled: 366
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus

Phyre2

PDB 1g5h chain A

3D model

Region: 234 - 636
Aligned: 363
Modelled: 374
Confidence: 100.0%
Identity: 14%
PDB header:dna binding protein
Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit;
PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma

Phyre2

PDB 2pmf chain A

3D model

Region: 255 - 642
Aligned: 385
Modelled: 388
Confidence: 100.0%
Identity: 20%
PDB header:ligase
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant

Phyre2

PDB 1tke chain A

3D model

Region: 1 - 225
Aligned: 225
Modelled: 224
Confidence: 100.0%
Identity: 100%
PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of the editing domain of threonyl-trna2 synthetase complexed with serine

Phyre2

PDB 3ikm chain C

3D model

Region: 234 - 636
Aligned: 358
Modelled: 368
Confidence: 100.0%
Identity: 15%
PDB header:transferase
Chain: C: PDB Molecule:dna polymerase subunit gamma-2;
PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme

Phyre2

PDB 2el9 chain B

3D model

Region: 258 - 632
Aligned: 355
Modelled: 364
Confidence: 100.0%
Identity: 16%
PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue

Phyre2

PDB 1qe0 chain B

3D model

Region: 258 - 629
Aligned: 335
Modelled: 370
Confidence: 100.0%
Identity: 18%
PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase

Phyre2
1

c1qf6A_
2

c1nyqA_
3

c3a32A_
4

c1fyfB_
5

c2i4lC_
6

d1nyra4
7

c2j3mA_
8

d1qf6a4
9

c1ggmB_
10

c3ialB_
11

c1atiA_
12

c1nj8C_
13

c1h4tD_
14

c1nj2A_
15

c1g5hA_
16

c2pmfA_
17

c1tkeA_
18

c3ikmC_
19

c2el9B_
20

c1qe0B_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1qf6A_



100.0 100 PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna
2c1nyqA_



100.0 44 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase 1;
PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate
3c3a32A_



100.0 30 PDB header:ligase
Chain: A: PDB Molecule:probable threonyl-trna synthetase 1;
PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix
4c1fyfB_



100.0 100 PDB header:ligase
Chain: B: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog
5c2i4lC_



100.0 22 PDB header:ligase
Chain: C: PDB Molecule:proline-trna ligase;
PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase
6d1nyra4



100.0 41 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
7c2j3mA_



100.0 22 PDB header:ligase
Chain: A: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol
8d1qf6a4



100.0 100 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
9c1ggmB_



100.0 19 PDB header:ligase
Chain: B: PDB Molecule:protein (glycyl-trna synthetase);
PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate
10c3ialB_



100.0 21 PDB header:ligase
Chain: B: PDB Molecule:prolyl-trna synthetase;
PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate
11c1atiA_



100.0 18 PDB header:protein biosynthesis
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus
12c1nj8C_



100.0 21 PDB header:ligase
Chain: C: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii
13c1h4tD_



100.0 23 PDB header:aminoacyl-trna synthetase
Chain: D: PDB Molecule:prolyl-trna synthetase;
PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline
14c1nj2A_



100.0 22 PDB header:ligase
Chain: A: PDB Molecule:proline-trna synthetase;
PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus
15c1g5hA_



100.0 14 PDB header:dna binding protein
Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit;
PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma
16c2pmfA_



100.0 20 PDB header:ligase
Chain: A: PDB Molecule:glycyl-trna synthetase;
PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant
17c1tkeA_



100.0 100 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of the editing domain of threonyl-trna2 synthetase complexed with serine
18c3ikmC_



100.0 15 PDB header:transferase
Chain: C: PDB Molecule:dna polymerase subunit gamma-2;
PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme
19c2el9B_



100.0 16 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue
20c1qe0B_



100.0 18 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase
21c1adyA_



not modelled 100.0 21 PDB header:trna synthetase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate
22c3netB_



not modelled 100.0 14 PDB header:ligase
Chain: B: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120
23c3hriF_



not modelled 100.0 15 PDB header:ligase
Chain: F: PDB Molecule:histidyl-trna synthetase;
PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei
24c2cj9A_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate
25c3qo8A_



not modelled 100.0 16 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic;
PDBTitle: crystal structure of seryl-trna synthetase from candida albicans
26c2dq0A_



not modelled 100.0 14 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog
27c1wu7A_



not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:histidyl-trna synthetase;
PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum
28c1sryB_



not modelled 100.0 13 PDB header:ligase(synthetase)
Chain: B: PDB Molecule:seryl-trna synthetase;
PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution
29d1seta2



not modelled 100.0 16 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
30c1wleB_



not modelled 100.0 20 PDB header:ligase
Chain: B: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate
31c2dq3A_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: crystal structure of aq_298
32d1nj8a3



not modelled 100.0 19 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
33c3lssA_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:seryl-trna synthetase;
PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp
34d1nyra3



not modelled 100.0 51 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:ThrRS/AlaRS common domain
Family:Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
35d1hc7a2



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
36d1tkea2



not modelled 100.0 100 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:ThrRS/AlaRS common domain
Family:Threonyl-tRNA synthetase (ThrRS), second 'additional' domain
37d1nj1a3



not modelled 100.0 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
38c3errB_



not modelled 100.0 16 PDB header:ligase
Chain: B: PDB Molecule:fusion protein of microtubule binding domain from
PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase
39c3od1A_



not modelled 100.0 13 PDB header:transferase
Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit;
PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c
40d1b76a2



not modelled 100.0 16 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
41d1atia2



not modelled 100.0 17 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
42c3mf2B_



not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:bll0957 protein;
PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp
43d1g5ha2



not modelled 100.0 15 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
44d1wu7a2



not modelled 100.0 15 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
45d2g4ca2



not modelled 100.0 12 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
46d1kmma2



not modelled 100.0 18 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
47c2zimA_



not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:pyrrolysyl-trna synthetase;
PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate
48d1qf6a1



not modelled 100.0 100 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
49c2znjB_



not modelled 100.0 16 PDB header:ligase
Chain: B: PDB Molecule:putative uncharacterized protein;
PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense
50d1nyra1



not modelled 100.0 44 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
51c3racA_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:histidine-trna ligase;
PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446.
52c2ztgA_



not modelled 100.0 17 PDB header:ligase
Chain: A: PDB Molecule:alanyl-trna synthetase;
PDBTitle: crystal structure of archaeoglobus fulgidus alanyl-trna2 synthetase lacking the c-terminal dimerization domain in3 complex with ala-sa
53c2zzfA_



not modelled 100.0 14 PDB header:ligase
Chain: A: PDB Molecule:alanyl-trna synthetase;
PDBTitle: crystal structure of alanyl-trna synthetase without2 oligomerization domain
54d1z7ma1



not modelled 100.0 18 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
55d1v4pa_



not modelled 100.0 20 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:ThrRS/AlaRS common domain
Family:AlaX-like
56d1h4vb2



not modelled 99.9 19 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
57c1z7nB_



not modelled 99.9 18 PDB header:transferase
Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit;
PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate
58d1nj8a1



not modelled 99.9 25 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
59d1nj1a1



not modelled 99.9 28 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
60d1qe0a2



not modelled 99.9 20 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
61c3kewA_



not modelled 99.9 17 PDB header:transferase
Chain: A: PDB Molecule:dhha1 domain protein;
PDBTitle: crystal structure of probable alanyl-trna-synthase from clostridium2 perfringens
62d1hc7a1



not modelled 99.9 29 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
63d1g5ha1



not modelled 99.9 17 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
64d1atia1



not modelled 99.9 23 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
65d2g4ca1



not modelled 99.9 17 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
66d1usya_



not modelled 99.9 11 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
67d1wu7a1



not modelled 99.9 18 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
68d1kmma1



not modelled 99.9 14 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
69d1qe0a1



not modelled 99.8 19 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
70c3g1zB_



not modelled 99.8 14 PDB header:ligase
Chain: B: PDB Molecule:putative lysyl-trna synthetase;
PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium
71d2e1ba2



not modelled 99.8 20 Fold:RRF/tRNA synthetase additional domain-like
Superfamily:ThrRS/AlaRS common domain
Family:AlaX-like
72c2e1bA_



not modelled 99.8 18 PDB header:ligase, hydrolase
Chain: A: PDB Molecule:216aa long hypothetical alanyl-trna synthetase;
PDBTitle: crystal structure of the alax-m trans-editing enzyme from2 pyrococcus horikoshii
73d1h4vb1



not modelled 99.8 17 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
74d1e1oa2



not modelled 99.8 13 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
75d1bbua2



not modelled 99.8 13 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
76c1wwtA_



not modelled 99.8 28 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase, cytoplasmic;
PDBTitle: solution structure of the tgs domain from human threonyl-2 trna synthetase
77d1c0aa3



not modelled 99.7 17 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
78c1b70A_



not modelled 99.7 16 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase;
PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine
79d1jjca_



not modelled 99.7 18 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
80d1eova2



not modelled 99.7 17 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
81d1nnha_



not modelled 99.7 14 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
82d1b8aa2



not modelled 99.6 17 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
83d1tkea1



not modelled 99.6 100 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:TGS domain
84c3l4gI_



not modelled 99.6 12 PDB header:ligase
Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain;
PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
85d1l0wa3



not modelled 99.6 21 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
86d1nyra2



not modelled 99.4 37 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:TGS domain
87c3e9hB_



not modelled 99.3 17 PDB header:ligase
Chain: B: PDB Molecule:lysyl-trna synthetase;
PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine
88c1e22A_



not modelled 99.3 14 PDB header:ligase
Chain: A: PDB Molecule:lysyl-trna synthetase;
PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp
89c2du4B_



not modelled 99.2 16 PDB header:ligase/rna
Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase;
PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys
90c2rhqA_



not modelled 99.1 11 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain;
PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies
91c2kmmA_



not modelled 99.1 22 PDB header:hydrolase
Chain: A: PDB Molecule:guanosine-3',5'-bis(diphosphate) 3'-
PDBTitle: solution nmr structure of the tgs domain of pg1808 from2 porphyromonas gingivalis. northeast structural genomics3 consortium target pgr122a (418-481)
92c3bjuB_



not modelled 99.0 18 PDB header:ligase
Chain: B: PDB Molecule:lysyl-trna synthetase;
PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase
93c1eqrC_



not modelled 99.0 19 PDB header:ligase
Chain: C: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli
94c1efwA_



not modelled 98.9 19 PDB header:ligase/rna
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli
95c3hvzB_



not modelled 98.9 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the tgs domain of the clolep_03100 protein from2 clostridium leptum, northeast structural genomics consortium target3 qlr13a
96c2xgtB_



not modelled 98.9 13 PDB header:ligase
Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic;
PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate
97c1x55A_



not modelled 98.9 13 PDB header:ligase
Chain: A: PDB Molecule:asparaginyl-trna synthetase;
PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue
98c1wydB_



not modelled 98.8 12 PDB header:ligase
Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase;
PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii
99c1asyA_



not modelled 98.8 17 PDB header:complex (aminoacyl-trna synthase/trna)
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp
100c3pcoC_



not modelled 98.8 16 PDB header:ligase
Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit;
PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp
101c1b8aB_



not modelled 98.8 15 PDB header:ligase
Chain: B: PDB Molecule:protein (aspartyl-trna synthetase);
PDBTitle: aspartyl-trna synthetase
102c2du7C_



not modelled 98.8 18 PDB header:ligase
Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase;
PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase
103c3m4qA_



not modelled 98.7 16 PDB header:ligase
Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative;
PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs)
104d1v95a_



not modelled 98.6 12 Fold:Anticodon-binding domain-like
Superfamily:Class II aaRS ABD-related
Family:Anticodon-binding domain of Class II aaRS
105c3ig2B_



not modelled 98.4 12 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: the crystal structure of a putative phenylalanyl-trna synthetase2 (phers) beta chain domain from bacteroides fragilis to 2.1a
106c3l4gL_



not modelled 98.3 13 PDB header:ligase
Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase
107c3icaB_



not modelled 98.2 14 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: the crystal structure of the beta subunit of a phenylalanyl-trna2 synthetase from porphyromonas gingivalis w83
108d1jjcb5



not modelled 98.0 16 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
109c3i7fA_



not modelled 97.9 16 PDB header:ligase
Chain: A: PDB Molecule:aspartyl-trna synthetase;
PDBTitle: aspartyl trna synthetase from entamoeba histolytica
110c2rhsB_



not modelled 97.5 8 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies
111c3cmqA_



not modelled 97.5 14 PDB header:ligase
Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial;
PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase
112d1wxqa2



not modelled 97.3 17 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:G domain-linked domain
113c2ekiA_



not modelled 97.2 20 PDB header:signaling protein
Chain: A: PDB Molecule:developmentally-regulated gtp-binding protein 1;
PDBTitle: solution structures of the tgs domain of human2 developmentally-regulated gtp-binding protein 1
114c1n9wA_



not modelled 97.1 20 PDB header:biosynthetic protein
Chain: A: PDB Molecule:aspartyl-trna synthetase 2;
PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus
115d1n9wa2



not modelled 97.0 21 Fold:Class II aaRS and biotin synthetases
Superfamily:Class II aaRS and biotin synthetases
Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain
116c3pcoD_



not modelled 96.9 16 PDB header:ligase
Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain;
PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp
117c2akwB_



not modelled 96.3 21 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine
118d1zud21



not modelled 95.5 12 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS
119d3c8ya2



not modelled 94.8 25 Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
120d1tygb_



not modelled 93.9 13 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0