Email l.a.kelley@imperial.ac.uk Description P76134 Date Thu Jan 5 12:19:23 GMT 2012 Unique Job ID 12c84bdfa13d7a73

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1tv8a_ 100.0 17 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:MoCo biosynthesis proteins 2 c2yx0A_ 99.9 13 PDB header:metal binding protein Chain: A: PDB Molecule:radical sam enzyme; PDBTitle: crystal structure of p. horikoshii tyw1 3 c3c8fA_ 99.8 15 PDB header:oxidoreductase Chain: A: PDB Molecule:pyruvate formate-lyase 1-activating enzyme; PDBTitle: 4fe-4s-pyruvate formate-lyase activating enzyme with2 partially disordered adomet 4 c2a5hC_ 99.6 15 PDB header:isomerase Chain: C: PDB Molecule:l-lysine 2,3-aminomutase; PDBTitle: 2.1 angstrom x-ray crystal structure of lysine-2,3-aminomutase from2 clostridium subterminale sb4, with michaelis analog (l-alpha-lysine3 external aldimine form of pyridoxal-5'-phosphate). 5 d1olta_ 99.6 10 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Oxygen-independent coproporphyrinogen III oxidase HemN 6 c1r30A_ 99.6 11 PDB header:transferase Chain: A: PDB Molecule:biotin synthase; PDBTitle: the crystal structure of biotin synthase, an s-2 adenosylmethionine-dependent radical enzyme 7 d1r30a_ 99.6 11 Fold:TIM beta/alpha-barrel Superfamily:Radical SAM enzymes Family:Biotin synthase 8 c3t7vA_ 99.5 13 PDB header:transferase Chain: A: PDB Molecule:methylornithine synthase pylb; PDBTitle: crystal structure of methylornithine synthase (pylb) 9 c3cixA_ 99.5 12 PDB header:adomet binding protein Chain: A: PDB Molecule:fefe-hydrogenase maturase; PDBTitle: x-ray structure of the [fefe]-hydrogenase maturase hyde from2 thermotoga maritima in complex with thiocyanate 10 c2z2uA_ 99.5 20 PDB header:metal binding protein Chain: A: PDB Molecule:upf0026 protein mj0257; PDBTitle: crystal structure of archaeal tyw1 11 c3canA_ 99.5 15 PDB header:lyase activator Chain: A: PDB Molecule:pyruvate-formate lyase-activating enzyme; PDBTitle: crystal structure of a domain of pyruvate-formate lyase-activating2 enzyme from bacteroides vulgatus atcc 8482 12 c3rfaA_ 99.4 16 PDB header:oxidoreductase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase n; PDBTitle: x-ray structure of rlmn from escherichia coli in complex with s-2 adenosylmethionine 13 c2qgqF_ 98.9 9 PDB header:structural genomics, unknown function Chain: F: PDB Molecule:protein tm_1862; PDBTitle: crystal structure of tm_1862 from thermotoga maritima.2 northeast structural genomics consortium target vr77 14 c3ivuB_ 97.2 12 PDB header:transferase Chain: B: PDB Molecule:homocitrate synthase, mitochondrial; PDBTitle: homocitrate synthase lys4 bound to 2-og 15 c3bleA_ 96.9 11 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 16 c3ewbX_ 96.9 11 PDB header:transferase Chain: X: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of n-terminal domain of putative 2-2 isopropylmalate synthase from listeria monocytogenes 17 c2ftpA_ 96.8 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of hydroxymethylglutaryl-coa lyase from pseudomonas2 aeruginosa 18 c2cw6B_ 95.9 11 PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria 19 c1ydoC_ 95.8 12 PDB header:lyase Chain: C: PDB Molecule:hmg-coa lyase; PDBTitle: crystal structure of the bacillis subtilis hmg-coa lyase, northeast2 structural genomics target sr181. 20 c1ydnA_ 95.4 7 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 21 c3eegB_ not modelled 93.7 8 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of a 2-isopropylmalate synthase from2 cytophaga hutchinsonii 22 c1nvmG_ not modelled 85.9 8 PDB header:lyase/oxidoreductase Chain: G: PDB Molecule:4-hydroxy-2-oxovalerate aldolase; PDBTitle: crystal structure of a bifunctional aldolase-dehydrogenase :2 sequestering a reactive and volatile intermediate 23 c1sr9A_ not modelled 84.6 9 PDB header:transferase Chain: A: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of leua from mycobacterium tuberculosis 24 c2qv5A_ not modelled 72.7 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu2773; PDBTitle: crystal structure of uncharacterized protein atu2773 from2 agrobacterium tumefaciens c58 25 d1nvma2 not modelled 70.9 9 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 26 c1rr2A_ not modelled 70.7 14 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 27 c2zyfA_ not modelled 69.1 11 PDB header:transferase Chain: A: PDB Molecule:homocitrate synthase; PDBTitle: crystal structure of homocitrate synthase from thermus thermophilus2 complexed with magnesuim ion and alpha-ketoglutarate 28 c3dxiB_ not modelled 65.9 9 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative aldolase; PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus 29 c2vefB_ not modelled 59.6 9 PDB header:transferase Chain: B: PDB Molecule:dihydropteroate synthase; PDBTitle: dihydropteroate synthase from streptococcus pneumoniae 30 c2nx9B_ not modelled 57.2 12 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 31 d2nlya1 not modelled 55.1 9 Fold:7-stranded beta/alpha barrel Superfamily:Glycoside hydrolase/deacetylase Family:Divergent polysaccharide deacetylase 32 c3iwpK_ not modelled 54.9 11 PDB header:metal binding protein Chain: K: PDB Molecule:copper homeostasis protein cutc homolog; PDBTitle: crystal structure of human copper homeostasis protein cutc 33 c2zq0B_ not modelled 54.3 11 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 34 c2bdqA_ not modelled 54.2 11 PDB header:metal transport Chain: A: PDB Molecule:copper homeostasis protein cutc; PDBTitle: crystal structure of the putative copper homeostasis2 protein cutc from streptococcus agalactiae, northeast3 strucural genomics target sar15. 35 d1muwa_ not modelled 53.7 8 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 36 c3hpxB_ not modelled 52.5 9 PDB header:transferase Chain: B: PDB Molecule:2-isopropylmalate synthase; PDBTitle: crystal structure of mycobacterium tuberculosis leua active site2 domain 1-425 (truncation mutant delta:426-644) 37 d1ajza_ not modelled 51.5 13 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 38 c3czkA_ not modelled 50.3 8 PDB header:hydrolase Chain: A: PDB Molecule:sucrose hydrolase; PDBTitle: crystal structure analysis of sucrose hydrolase(suh) e322q-2 sucrose complex 39 d1tx2a_ not modelled 50.1 15 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 40 c1tx2A_ not modelled 50.1 15 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 41 d1g5aa2 not modelled 49.8 8 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 42 c3bg3B_ not modelled 47.8 14 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase, mitochondrial; PDBTitle: crystal structure of human pyruvate carboxylase (missing2 the biotin carboxylase domain at the n-terminus) 43 d2zdra2 not modelled 47.6 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 44 c1jgiA_ not modelled 47.5 8 PDB header:transferase Chain: A: PDB Molecule:amylosucrase; PDBTitle: crystal structure of the active site mutant glu328gln of2 amylosucrase from neisseria polysaccharea in complex with3 the natural substrate sucrose 45 c3n2xB_ not modelled 46.8 13 PDB header:lyase Chain: B: PDB Molecule:uncharacterized protein yage; PDBTitle: crystal structure of yage, a prophage protein belonging to the2 dihydrodipicolinic acid synthase family from e. coli k12 in complex3 with pyruvate 46 c3ol0C_ not modelled 45.0 14 PDB header:de novo protein Chain: C: PDB Molecule:de novo designed monomer trefoil-fold sub-domain which PDBTitle: crystal structure of monofoil-4p homo-trimer: de novo designed monomer2 trefoil-fold sub-domain which forms homo-trimer assembly 47 c2knpA_ not modelled 44.9 43 PDB header:unknown function Chain: A: PDB Molecule:mcocc-1; PDBTitle: isolation and characterization of peptides from momordica2 cochinchinensis seeds. 48 d1twda_ not modelled 44.3 10 Fold:TIM beta/alpha-barrel Superfamily:CutC-like Family:CutC-like 49 d1yhta1 not modelled 40.9 15 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 50 c3dz1A_ not modelled 39.1 11 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 rhodopseudomonas palustris at 1.87a resolution 51 c3chvA_ not modelled 36.8 13 PDB header:metal binding protein Chain: A: PDB Molecule:prokaryotic domain of unknown function (duf849) with a tim PDBTitle: crystal structure of a prokaryotic domain of unknown function (duf849)2 member (spoa0042) from silicibacter pomeroyi dss-3 at 1.45 a3 resolution 52 c2gjxE_ not modelled 35.3 9 PDB header:hydrolase Chain: E: PDB Molecule:beta-hexosaminidase alpha chain; PDBTitle: crystallographic structure of human beta-hexosaminidase a 53 c2ekcA_ not modelled 33.8 11 PDB header:lyase Chain: A: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: structural study of project id aq_1548 from aquifex aeolicus vf5 54 c3hf3A_ not modelled 33.7 20 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 55 c3lciA_ not modelled 31.1 15 PDB header:lyase Chain: A: PDB Molecule:n-acetylneuraminate lyase; PDBTitle: the d-sialic acid aldolase mutant v251w 56 d1qwga_ not modelled 30.5 14 Fold:TIM beta/alpha-barrel Superfamily:(2r)-phospho-3-sulfolactate synthase ComA Family:(2r)-phospho-3-sulfolactate synthase ComA 57 c3cprB_ not modelled 29.9 11 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthetase; PDBTitle: the crystal structure of corynebacterium glutamicum2 dihydrodipicolinate synthase to 2.2 a resolution 58 d1qt1a_ not modelled 29.8 9 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 59 c2v9dB_ not modelled 26.9 13 PDB header:lyase Chain: B: PDB Molecule:yage; PDBTitle: crystal structure of yage, a prophage protein belonging to2 the dihydrodipicolinic acid synthase family from e. coli3 k12 60 c3navB_ not modelled 26.5 11 PDB header:lyase Chain: B: PDB Molecule:tryptophan synthase alpha chain; PDBTitle: crystal structure of an alpha subunit of tryptophan synthase from2 vibrio cholerae o1 biovar el tor str. n16961 61 d2a6na1 not modelled 26.2 11 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 62 d1v93a_ not modelled 25.5 15 Fold:TIM beta/alpha-barrel Superfamily:FAD-linked oxidoreductase Family:Methylenetetrahydrofolate reductase 63 c1ps9A_ not modelled 25.3 12 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 64 c3rpmA_ not modelled 25.2 14 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetyl-hexosaminidase; PDBTitle: crystal structure of the first gh20 domain of a novel beta-n-acetyl-2 hexosaminidase strh from streptococcus pneumoniae r6 65 c3e02A_ not modelled 25.2 11 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein duf849; PDBTitle: crystal structure of a duf849 family protein (bxe_c0271) from2 burkholderia xenovorans lb400 at 1.90 a resolution 66 d1hl2a_ not modelled 25.1 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 67 d1ad1a_ not modelled 25.1 9 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 68 c1nouA_ not modelled 25.0 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase beta chain; PDBTitle: native human lysosomal beta-hexosaminidase isoform b 69 d1m53a2 not modelled 24.3 10 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 70 c1qysA_ not modelled 24.2 13 PDB header:de novo protein Chain: A: PDB Molecule:top7; PDBTitle: crystal structure of top7: a computationally designed2 protein with a novel fold 71 c2ylaA_ not modelled 24.1 12 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: inhibition of the pneumococcal virulence factor strh and2 molecular insights into n-glycan recognition and3 hydrolysis 72 c2g7zB_ not modelled 23.8 5 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:conserved hypothetical protein spy1493; PDBTitle: conserved degv-like protein of unknown function from streptococcus2 pyogenes m1 gas binds long-chain fatty acids 73 c3khdC_ not modelled 23.6 7 PDB header:transferase Chain: C: PDB Molecule:pyruvate kinase; PDBTitle: crystal structure of pff1300w. 74 d1nowa1 not modelled 22.1 13 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 75 d1z41a1 not modelled 22.1 11 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 76 c2ou4C_ not modelled 21.1 9 PDB header:isomerase Chain: C: PDB Molecule:d-tagatose 3-epimerase; PDBTitle: crystal structure of d-tagatose 3-epimerase from2 pseudomonas cichorii 77 c3b4uB_ not modelled 20.6 11 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from agrobacterium2 tumefaciens str. c58 78 c2qmaB_ not modelled 20.4 18 PDB header:transferase Chain: B: PDB Molecule:diaminobutyrate-pyruvate transaminase and l-2,4- PDBTitle: crystal structure of glutamate decarboxylase domain of2 diaminobutyrate-pyruvate transaminase and l-2,4-diaminobutyrate3 decarboxylase from vibrio parahaemolyticus 79 c3g0sA_ not modelled 20.1 13 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: dihydrodipicolinate synthase from salmonella typhimurium lt2 80 c3fluD_ not modelled 20.0 10 PDB header:lyase Chain: D: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from the pathogen2 neisseria meningitidis 81 d1uwva2 not modelled 19.9 45 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:(Uracil-5-)-methyltransferase 82 d1eyea_ not modelled 19.8 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 83 c3pueA_ not modelled 19.7 15 PDB header:lyase Chain: A: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of the complex of dhydrodipicolinate synthase from2 acinetobacter baumannii with lysine at 2.6a resolution 84 c2jvfA_ not modelled 19.6 17 PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein 85 c3qfeB_ not modelled 19.6 8 PDB header:lyase Chain: B: PDB Molecule:putative dihydrodipicolinate synthase family protein; PDBTitle: crystal structures of a putative dihydrodipicolinate synthase family2 protein from coccidioides immitis 86 c3lmyA_ not modelled 19.3 8 PDB header:hydrolase Chain: A: PDB Molecule:beta-hexosaminidase subunit beta; PDBTitle: the crystal structure of beta-hexosaminidase b in complex with2 pyrimethamine 87 c1xuzA_ not modelled 19.0 16 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 88 c2dh3A_ not modelled 18.6 21 PDB header:transport protein, signaling protein Chain: A: PDB Molecule:4f2 cell-surface antigen heavy chain; PDBTitle: crystal structure of human ed-4f2hc 89 c3ogfA_ not modelled 18.3 10 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed dimeric trefoil-fold sub-domain which PDBTitle: crystal structure of difoil-4p homo-trimer: de novo designed dimeric2 trefoil-fold sub-domain which forms homo-trimer assembly 90 c3ct7E_ not modelled 17.5 11 PDB header:isomerase Chain: E: PDB Molecule:d-allulose-6-phosphate 3-epimerase; PDBTitle: crystal structure of d-allulose 6-phosphate 3-epimerase2 from escherichia coli k-12 91 c3lppA_ not modelled 16.7 14 PDB header:hydrolase Chain: A: PDB Molecule:sucrase-isomaltase; PDBTitle: crystal complex of n-terminal sucrase-isomaltase with kotalanol 92 c3rcnA_ not modelled 16.7 13 PDB header:hydrolase Chain: A: PDB Molecule:beta-n-acetylhexosaminidase; PDBTitle: crystal structure of beta-n-acetylhexosaminidase from arthrobacter2 aurescens 93 c3no5C_ not modelled 16.4 15 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a pfam duf849 domain containing protein2 (reut_a1631) from ralstonia eutropha jmp134 at 1.90 a resolution 94 c1uwvA_ not modelled 16.0 50 PDB header:transferase Chain: A: PDB Molecule:23s rrna (uracil-5-)-methyltransferase ruma; PDBTitle: crystal structure of ruma, the iron-sulfur cluster2 containing e. coli 23s ribosomal rna 5-methyluridine3 methyltransferase 95 d1qbaa3 not modelled 15.6 23 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-N-acetylhexosaminidase catalytic domain 96 c2ehhE_ not modelled 15.6 16 PDB header:lyase Chain: E: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from2 aquifex aeolicus 97 d1o5ka_ not modelled 15.5 10 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class I aldolase 98 c3daqB_ not modelled 15.4 9 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from methicillin-2 resistant staphylococcus aureus 99 c2rfgB_ not modelled 15.3 9 PDB header:lyase Chain: B: PDB Molecule:dihydrodipicolinate synthase; PDBTitle: crystal structure of dihydrodipicolinate synthase from hahella2 chejuensis at 1.5a resolution