Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	R	V	S	I	T	E	R	P	D	W	R	E	K	A	H	E	Y	G	F	N	F	H	T	M	Y	G	E	P	Y	W	C	E	D	A	Y	Y	K	L	T	L	A	Q	V	E	K	L	E	E	V	T	A	E	L	H	Q	M	C	L
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	V	V	E	K	V	I	A	S	D	E	L	M	T	K	F	R	I	P	K	H	T	W	S	F	V	R	Q	S	W	L	T	H	Q	P	S	L	Y	S	R	L	D	L	A	W	D	G	T	G	E	P	K	L	L	E	N	N	A	D	T
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	T	S	L	Y	E	A	A	F	F	Q	W	I	W	L	E	D	Q	L	N	A	G	N	L	P	E	G	S	D	Q	F	N	S	L	Q	E	K	L	I	D	R	F	V	E	L	R	E	Q	Y	G	F	Q	L	L	H	L	T	C	C	R
Secondary structure
SS confidence
Disorder																					?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		D	T	V	E	D	R	G	T	I	Q	Y	L	Q	D	C	A	T	E	A	E	I	A	T	E	F	L	Y	I	D	D	I	G	L	G	E	K	G	Q	F	T	D	L	Q	D	Q	V	I	S	N	L	F	K	L	Y	P	W	E	F	M	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	E	M	F	S	T	K	L	E	D	A	G	V	R	W	L	E	P	A	W	K	S	I	I	S	N	K	A	L	L	P	L	L	W	E	M	F	P	N	H	P	N	L	L	P	A	Y	F	A	E	D	D	H	P	Q	M	E	K	Y	V
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		V	K	P	I	F	S	R	E	G	A	N	V	S	I	I	E	N	G	K	T	I	E	A	A	E	G	P	Y	G	E	E	G	M	I	V	Q	Q	F	H	P	L	P	K	F	G	D	S	Y	M	L	I	G	S	W	L	V	N	D	Q	P
Secondary structure
SS confidence
Disorder																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
Sequence		A	G	I	G	I	R	E	D	R	A	L	I	T	Q	D	M	S	R	F	Y	P	H	I	F	V	E
Secondary structure
SS confidence
Disorder														?											?		?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ioa chain A Region: 33 - 386 Aligned: 342 Modelled: 354 Confidence: 100.0% Identity: 28% PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor Phyre2 PDB 2vpm chain B Region: 37 - 384 Aligned: 316 Modelled: 322 Confidence: 100.0% Identity: 29% PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase Phyre2 PDB 2io8 chain A domain 3 Region: 11 - 383 Aligned: 270 Modelled: 271 Confidence: 100.0% Identity: 33% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Glutathionylspermidine synthase ATP-binding domain-like Phyre2 PDB 3n6x chain A Region: 1 - 377 Aligned: 360 Modelled: 376 Confidence: 100.0% Identity: 13% PDB header:ligase Chain: A: PDB Molecule:putative glutathionylspermidine synthase; PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution Phyre2 PDB 2io8 chain A domain 1 Region: 171 - 279 Aligned: 108 Modelled: 109 Confidence: 99.8% Identity: 20% Fold: PreATP-grasp domain Superfamily: PreATP-grasp domain Family: Glutathionylspermidine synthase substrate-binding domain-like Phyre2 PDB 2hgs chain A Region: 11 - 384 Aligned: 358 Modelled: 368 Confidence: 99.5% Identity: 15% PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase Phyre2 PDB 3kal chain B Region: 37 - 366 Aligned: 316 Modelled: 330 Confidence: 99.5% Identity: 17% PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound Phyre2 PDB 1m0t chain B Region: 37 - 366 Aligned: 313 Modelled: 330 Confidence: 99.3% Identity: 16% PDB header:ligase Chain: B: PDB Molecule:glutathione synthetase; PDBTitle: yeast glutathione synthase Phyre2 PDB 2wyo chain C Region: 11 - 384 Aligned: 353 Modelled: 359 Confidence: 99.3% Identity: 17% PDB header:ligase Chain: C: PDB Molecule:glutathione synthetase; PDBTitle: trypanosoma brucei glutathione synthetase Phyre2 PDB 1gsh chain A Region: 173 - 368 Aligned: 185 Modelled: 196 Confidence: 99.1% Identity: 14% PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 Phyre2 PDB 2p0a chain A Region: 171 - 377 Aligned: 200 Modelled: 207 Confidence: 98.5% Identity: 13% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp Phyre2 PDB 1i7n chain A Region: 244 - 377 Aligned: 128 Modelled: 134 Confidence: 98.3% Identity: 13% PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain Phyre2 PDB 1pk8 chain D Region: 243 - 386 Aligned: 138 Modelled: 144 Confidence: 98.2% Identity: 13% PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp Phyre2 PDB 1uc8 chain B Region: 174 - 373 Aligned: 175 Modelled: 200 Confidence: 98.2% Identity: 13% PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 Phyre2 PDB 2hgs chain A domain 4 Region: 11 - 384 Aligned: 267 Modelled: 273 Confidence: 98.0% Identity: 16% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Eukaryotic glutathione synthetase ATP-binding domain Phyre2 PDB 2qb5 chain B Region: 192 - 384 Aligned: 173 Modelled: 193 Confidence: 98.0% Identity: 13% PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ Phyre2 PDB 1pk8 chain A domain 2 Region: 257 - 375 Aligned: 114 Modelled: 119 Confidence: 97.9% Identity: 8% Fold: ATP-grasp Superfamily: Glutathione synthetase ATP-binding domain-like Family: Synapsin C-terminal domain Phyre2 PDB 2dln chain A Region: 171 - 374 Aligned: 191 Modelled: 204 Confidence: 97.6% Identity: 12% PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution Phyre2 PDB 3ln6 chain A Region: 257 - 375 Aligned: 107 Modelled: 119 Confidence: 97.4% Identity: 20% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae Phyre2 PDB 3ln7 chain A Region: 298 - 380 Aligned: 75 Modelled: 83 Confidence: 97.4% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida Phyre2 1 c2ioaA_ 2 c2vpmB_ 3 d2io8a3 4 c3n6xA_ 5 d2io8a1 6 c2hgsA_ 7 c3kalB_ 8 c1m0tB_ 9 c2wyoC_ 10 c1gshA_ 11 c2p0aA_ 12 c1i7nA_ 13 c1pk8D_ 14 c1uc8B_ 15 d2hgsa4 16 c2qb5B_ 17 d1pk8a2 18 c2dlnA_ 19 c3ln6A_ 20 c3ln7A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2ioaA_ 100.0 28 PDB header:ligase, hydrolase Chain: A: PDB Molecule:bifunctional glutathionylspermidine PDBTitle: e. coli bifunctional glutathionylspermidine2 synthetase/amidase incomplex with mg2+ and adp and3 phosphinate inhibitor 2 c2vpmB_ 100.0 29 PDB header:ligase Chain: B: PDB Molecule:trypanothione synthetase; PDBTitle: trypanothione synthetase 3 d2io8a3 100.0 33 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Glutathionylspermidine synthase ATP-binding domain-like 4 c3n6xA_ 100.0 13 PDB header:ligase Chain: A: PDB Molecule:putative glutathionylspermidine synthase; PDBTitle: crystal structure of a putative glutathionylspermidine synthase2 (mfla_0391) from methylobacillus flagellatus kt at 2.35 a resolution 5 d2io8a1 99.8 20 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Glutathionylspermidine synthase substrate-binding domain-like 6 c2hgsA_ 99.5 15 PDB header:amine/carboxylate ligase Chain: A: PDB Molecule:protein (glutathione synthetase); PDBTitle: human glutathione synthetase 7 c3kalB_ 99.5 17 PDB header:ligase Chain: B: PDB Molecule:homoglutathione synthetase; PDBTitle: structure of homoglutathione synthetase from glycine max in2 closed conformation with homoglutathione, adp, a sulfate3 ion, and three magnesium ions bound 8 c1m0tB_ 99.3 16 PDB header:ligase Chain: B: PDB Molecule:glutathione synthetase; PDBTitle: yeast glutathione synthase 9 c2wyoC_ 99.3 17 PDB header:ligase Chain: C: PDB Molecule:glutathione synthetase; PDBTitle: trypanosoma brucei glutathione synthetase 10 c1gshA_ 99.1 14 PDB header:glutathione biosynthesis ligase Chain: A: PDB Molecule:glutathione biosynthetic ligase; PDBTitle: structure of escherichia coli glutathione synthetase at ph 7.5 11 c2p0aA_ 98.5 13 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin-3; PDBTitle: the crystal structure of human synapsin iii (syn3) in complex with2 amppnp 12 c1i7nA_ 98.3 13 PDB header:neuropeptide Chain: A: PDB Molecule:synapsin ii; PDBTitle: crystal structure analysis of the c domain of synapsin ii2 from rat brain 13 c1pk8D_ 98.2 13 PDB header:membrane protein Chain: D: PDB Molecule:rat synapsin i; PDBTitle: crystal structure of rat synapsin i c domain complexed to2 ca.atp 14 c1uc8B_ 98.2 13 PDB header:biosynthetic protein Chain: B: PDB Molecule:lysine biosynthesis enzyme; PDBTitle: crystal structure of a lysine biosynthesis enzyme, lysx,2 from thermus thermophilus hb8 15 d2hgsa4 98.0 16 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Eukaryotic glutathione synthetase ATP-binding domain 16 c2qb5B_ 98.0 13 PDB header:transferase Chain: B: PDB Molecule:inositol-tetrakisphosphate 1-kinase; PDBTitle: crystal structure of human inositol 1,3,4-trisphosphate 5/6-kinase2 (itpk1) in complex with adp and mn2+ 17 d1pk8a2 97.9 8 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 18 c2dlnA_ 97.6 12 PDB header:ligase(peptidoglycan synthesis) Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: vancomycin resistance: structure of d-alanine:d-alanine2 ligase at 2.3 angstroms resolution 19 c3ln6A_ 97.4 20 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 streptococcus agalactiae 20 c3ln7A_ 97.4 17 PDB header:ligase Chain: A: PDB Molecule:glutathione biosynthesis bifunctional protein gshab; PDBTitle: crystal structure of a bifunctional glutathione synthetase from2 pasteurella multocida 21 d1i7na2 not modelled 97.3 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Synapsin C-terminal domain 22 c3t9aA_ not modelled 97.2 16 PDB header:transferase Chain: A: PDB Molecule:inositol pyrophosphate kinase; PDBTitle: crystal structure of the catalytic domain of human diphosphoinositol2 pentakisphosphate kinase 2 (ppip5k2) in complex with amppnp at ph 7.0 23 c1kjjA_ not modelled 97.1 14 PDB header:transferase Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2; PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s 24 c2yyaB_ not modelled 97.1 14 PDB header:ligase Chain: B: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of gar synthetase from aquifex aeolicus 25 c2xd4A_ not modelled 97.0 13 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: nucleotide-bound structures of bacillus subtilis glycinamide2 ribonucleotide synthetase 26 c3tqtB_ not modelled 97.0 13 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: structure of the d-alanine-d-alanine ligase from coxiella burnetii 27 c3i12A_ not modelled 97.0 13 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: the crystal structure of the d-alanyl-alanine synthetase a from2 salmonella enterica subsp. enterica serovar typhimurium str. lt2 28 d1gsaa2 not modelled 96.8 18 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 29 d1m0wa2 not modelled 96.7 17 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Eukaryotic glutathione synthetase ATP-binding domain 30 c1e4eB_ not modelled 96.7 9 PDB header:ligase Chain: B: PDB Molecule:vancomycin/teicoplanin a-type resistance protein vana; PDBTitle: d-alanyl-d-lacate ligase 31 c2pvpB_ not modelled 96.7 12 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: crystal structure of d-alanine-d-alanine ligase from helicobacter2 pylori 32 c3lp8A_ not modelled 96.4 17 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine-glycine ligase; PDBTitle: crystal structure of phosphoribosylamine-glycine ligase from2 ehrlichia chaffeensis 33 c3lwbA_ not modelled 96.3 13 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of apo d-alanine:d-alanine ligase (ddl) from2 mycobacterium tuberculosis 34 c3bg5C_ not modelled 96.1 16 PDB header:ligase Chain: C: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of staphylococcus aureus pyruvate2 carboxylase 35 c2hjwA_ not modelled 95.9 14 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: crystal structure of the bc domain of acc2 36 d1gsaa1 not modelled 95.8 9 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:Prokaryotic glutathione synthetase, N-terminal domain 37 c2ip4A_ not modelled 95.8 19 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of glycinamide ribonucleotide synthetase from2 thermus thermophilus hb8 38 c2zdqA_ not modelled 95.7 18 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine:d-alanine ligase with atp2 and d-alanine:d-alanine from thermus thermophius hb8 39 c1vkzA_ not modelled 95.5 14 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylamine--glycine ligase; PDBTitle: crystal structure of phosphoribosylamine--glycine ligase (tm1250) from2 thermotoga maritima at 2.30 a resolution 40 c1z2pX_ not modelled 95.5 15 PDB header:transferase Chain: X: PDB Molecule:inositol 1,3,4-trisphosphate 5/6-kinase; PDBTitle: inositol 1,3,4-trisphosphate 5/6-kinase in complex with mg2+/amp-2 pcp/ins(1,3,4)p3 41 c3tinA_ not modelled 95.4 15 PDB header:ligase Chain: A: PDB Molecule:ttl protein; PDBTitle: tubulin tyrosine ligase 42 c2dzdB_ not modelled 95.2 11 PDB header:ligase Chain: B: PDB Molecule:pyruvate carboxylase; PDBTitle: crystal structure of the biotin carboxylase domain of2 pyruvate carboxylase 43 c1ehiB_ not modelled 95.2 9 PDB header:ligase Chain: B: PDB Molecule:d-alanine:d-lactate ligase; PDBTitle: d-alanine:d-lactate ligase (lmddl2) of vancomycin-resistant2 leuconostoc mesenteroides 44 c1w96B_ not modelled 95.1 11 PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a 45 c3g8cB_ not modelled 95.0 11 PDB header:ligase Chain: B: PDB Molecule:biotin carboxylase; PDBTitle: crystal stucture of biotin carboxylase in complex with2 biotin, bicarbonate, adp and mg ion 46 c3ouzA_ not modelled 94.9 15 PDB header:ligase Chain: A: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of biotin carboxylase-adp complex from campylobacter2 jejuni 47 c2cqyA_ not modelled 94.8 13 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: solution structure of b domain from human propionyl-coa2 carboxylase alpha subunit 48 d1uc8a2 not modelled 94.4 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:Lysine biosynthesis enzyme LysX ATP-binding domain 49 c3df7A_ not modelled 94.4 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative atp-grasp superfamily protein; PDBTitle: crystal structure of a putative atp-grasp superfamily2 protein from archaeoglobus fulgidus 50 c1ulzA_ not modelled 94.3 18 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase n-terminal domain; PDBTitle: crystal structure of the biotin carboxylase subunit of pyruvate2 carboxylase 51 c2vpqA_ not modelled 94.0 14 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase; PDBTitle: crystal structure of biotin carboxylase from s. aureus2 complexed with amppnp 52 c3orqA_ not modelled 93.9 9 PDB header:ligase,biosynthetic protein Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp 53 c3gidB_ not modelled 93.9 11 PDB header:ligase Chain: B: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: the biotin carboxylase (bc) domain of human acetyl-coa2 carboxylase 2 (acc2) in complex with soraphen a 54 c3uvzB_ not modelled 93.8 9 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria 55 c3k5iB_ not modelled 93.7 9 PDB header:lyase Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase; PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide 56 d1w96a3 not modelled 92.9 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 57 d1e4ea2 not modelled 91.8 23 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 58 c2i80B_ not modelled 91.1 24 PDB header:ligase Chain: B: PDB Molecule:d-alanine-d-alanine ligase; PDBTitle: allosteric inhibition of staphylococcus aureus d-alanine:d-alanine2 ligase revealed by crystallographic studies 59 c3se7A_ not modelled 90.9 11 PDB header:ligase Chain: A: PDB Molecule:vana; PDBTitle: ancient vana 60 d1a9xa5 not modelled 90.8 12 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 61 d1gsoa3 not modelled 90.4 32 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 62 c2ys6A_ not modelled 90.0 13 PDB header:ligase Chain: A: PDB Molecule:phosphoribosylglycinamide synthetase; PDBTitle: crystal structure of gar synthetase from geobacillus kaustophilus 63 d2r85a2 not modelled 89.4 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 64 d1ehia2 not modelled 88.8 33 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 65 c3e5nA_ not modelled 88.8 23 PDB header:ligase Chain: A: PDB Molecule:d-alanine-d-alanine ligase a; PDBTitle: crystal strucutre of d-alanine-d-alanine ligase from2 xanthomonas oryzae pv. oryzae kacc10331 66 d2r7ka2 not modelled 88.7 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:PurP ATP-binding domain-like 67 d1vkza3 not modelled 87.8 14 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 68 d1iowa2 not modelled 87.7 36 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:ATP-binding domain of peptide synthetases 69 c3k3pA_ not modelled 86.8 33 PDB header:ligase Chain: A: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of the apo form of d-alanine:d-alanine ligase (ddl)2 from streptococcus mutans 70 c1m6vE_ not modelled 85.5 14 PDB header:ligase Chain: E: PDB Molecule:carbamoyl phosphate synthetase large chain; PDBTitle: crystal structure of the g359f (small subunit) point mutant of2 carbamoyl phosphate synthetase 71 c3q2oB_ not modelled 83.7 10 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit; PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase 72 c3r23B_ not modelled 83.4 9 PDB header:ligase Chain: B: PDB Molecule:d-alanine--d-alanine ligase; PDBTitle: crystal structure of d-alanine--d-alanine ligase from bacillus2 anthracis 73 d1kjqa3 not modelled 79.0 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 74 c1gsoA_ not modelled 75.7 32 PDB header:ligase Chain: A: PDB Molecule:protein (glycinamide ribonucleotide synthetase); PDBTitle: glycinamide ribonucleotide synthetase (gar-syn) from e.2 coli. 75 c2z04A_ not modelled 75.5 8 PDB header:lyase Chain: A: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure of phosphoribosylaminoimidazole2 carboxylase atpase subunit from aquifex aeolicus 76 c3u9sE_ not modelled 74.4 18 PDB header:ligase Chain: E: PDB Molecule:methylcrotonyl-coa carboxylase, alpha-subunit; PDBTitle: crystal structure of p. aeruginosa 3-methylcrotonyl-coa carboxylase2 (mcc) 750 kd holoenzyme, coa complex 77 d3etja3 not modelled 73.9 7 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 78 d1ulza3 not modelled 72.6 10 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 79 c2r85B_ not modelled 72.0 15 PDB header:unknown function Chain: B: PDB Molecule:purp protein pf1517; PDBTitle: crystal structure of purp from pyrococcus furiosus complexed with amp 80 c3n6rK_ not modelled 70.9 23 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 81 c2pn1A_ not modelled 70.1 13 PDB header:ligase Chain: A: PDB Molecule:carbamoylphosphate synthase large subunit; PDBTitle: crystal structure of carbamoylphosphate synthase large subunit (split2 gene in mj) (zp_00538348.1) from exiguobacterium sp. 255-15 at 2.00 a3 resolution 82 c2dwcB_ not modelled 67.0 8 PDB header:transferase Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp 83 c2qk4A_ not modelled 63.0 12 PDB header:ligase Chain: A: PDB Molecule:trifunctional purine biosynthetic protein adenosine-3; PDBTitle: human glycinamide ribonucleotide synthetase 84 c3etjB_ not modelled 59.0 12 PDB header:lyase Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase atpase PDBTitle: crystal structure e. coli purk in complex with mg, adp, and2 pi 85 c2gpwC_ not modelled 56.7 14 PDB header:ligase Chain: C: PDB Molecule:biotin carboxylase; PDBTitle: crystal structure of the biotin carboxylase subunit, f363a2 mutant, of acetyl-coa carboxylase from escherichia coli. 86 d2j9ga3 not modelled 55.5 9 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 87 d1a9xa6 not modelled 47.5 15 Fold:ATP-grasp Superfamily:Glutathione synthetase ATP-binding domain-like Family:BC ATP-binding domain-like 88 c3k1tA_ not modelled 44.2 15 PDB header:ligase Chain: A: PDB Molecule:glutamate--cysteine ligase gsha; PDBTitle: crystal structure of putative gamma-glutamylcysteine synthetase2 (yp_546622.1) from methylobacillus flagellatus kt at 1.90 a3 resolution 89 c3l4eA_ not modelled 27.9 15 PDB header:hydrolase Chain: A: PDB Molecule:uncharacterized peptidase lmo0363; PDBTitle: 1.5a crystal structure of a putative peptidase e protein from listeria2 monocytogenes egd-e 90 c3oetF_ not modelled 23.7 25 PDB header:oxidoreductase Chain: F: PDB Molecule:erythronate-4-phosphate dehydrogenase; PDBTitle: d-erythronate-4-phosphate dehydrogenase complexed with nad 91 c3d3kD_ not modelled 22.1 7 PDB header:protein binding Chain: D: PDB Molecule:enhancer of mrna-decapping protein 3; PDBTitle: crystal structure of human edc3p 92 d1v65a_ not modelled 20.5 14 Fold:KRAB domain (Kruppel-associated box) Superfamily:KRAB domain (Kruppel-associated box) Family:KRAB domain (Kruppel-associated box) 93 c2o4cB_ not modelled 20.3 19 PDB header:oxidoreductase Chain: B: PDB Molecule:erythronate-4-phosphate dehydrogenase; PDBTitle: crystal structure of d-erythronate-4-phosphate dehydrogenase complexed2 with nad 94 d2q22a1 not modelled 18.1 11 Fold:Ava3019-like Superfamily:Ava3019-like Family:Ava3019-like 95 c3e90C_ not modelled 17.6 33 PDB header:hydrolase Chain: C: PDB Molecule:ns2b cofactor; PDBTitle: west nile vi rus ns2b-ns3protease in complexed with2 inhibitor naph-kkr-h 96 d2oo3a1 not modelled 17.4 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:LPG1296-like 97 c2ijoA_ not modelled 16.4 33 PDB header:hydrolase/hydrolase inhibitor Chain: A: PDB Molecule:polyprotein; PDBTitle: crystal structure of the west nile virus ns2b-ns3 protease2 complexed with bovine pancreatic trypsin inhibitor 98 c1f13A_ not modelled 15.5 14 PDB header:coagulation factor Chain: A: PDB Molecule:cellular coagulation factor xiii zymogen; PDBTitle: recombinant human cellular coagulation factor xiii 99 c2r7mA_ not modelled 14.0 12 PDB header:ligase Chain: A: PDB Molecule:5-formaminoimidazole-4-carboxamide-1-(beta)-d- PDBTitle: crystal structure of faicar synthetase (purp) from m.2 jannaschii complexed with amp

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0