Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionA0AVT1
DateTue Apr 3 14:58:27 BST 2012
Unique Job ID13c0206945bc8832

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3cmmA_
Top template information
PDB header:ligase/protein binding
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of the uba1-ubiquitin complex
Confidence and coverage
Confidence:100.0% Coverage: 93%
980 residues ( 93% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEGSEPVAAHQGEEASCSSWGTGSTNKNLPIMSTASVEIDDALYSRQRYVLGDTAMQKMA
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Disorder  ?????



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   .........70.........80.........90.........100.........110.........120
Sequence  KSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTEKCQAWDLGTNFFLSEDDVVNKRNRAE
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   .........130.........140.........150.........160.........170.........180
Sequence  AVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKYQCVVLTEMKLPLQKKINDFCRSQCPP
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   .........190.........200.........210.........220.........230.........240
Sequence  IKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPKEIFISNITQANPGIVTCLENHPHKLE
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   .........250.........260.........270.........280.........290.........300
Sequence  TGQFLTFREINGMTGLNGSIQQITVISPFSFSIGDTTELEPYLHGGIAVQVKTPKTVFFE
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   .........310.........320.........330.........340.........350.........360
Sequence  SLERQLKHPKCLIVDFSNPEAPLEIHTAMLALDQFQEKYSRKPNVGCQQDSEELLKLATS
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   .........370.........380.........390.........400.........410.........420
Sequence  ISETLEEKPDVNADIVHWLSWTAQGFLSPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLE
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   .........430.........440.........450.........460.........470.........480
Sequence  AADIVESLGKPECEEFLPRGDRYDALRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFA
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   .........490.........500.........510.........520.........530.........540
Sequence  LLGVGTSKEKGMITVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDA
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   .........550.........560.........570.........580.........590.........600
Sequence  HLNKVCPTTETIYNDEFYTKQDVIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHT
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   .........610.........620.........630.........640.........650.........660
Sequence  EVIVPHLTESYNSHRDPPEEEIPFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFW
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   .........670.........680.........690.........700.........710.........720
Sequence  QTYSSAEEVLQKIQSGHSLEGCFQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLH
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   .........730.........740.........750.........760.........770.........780
Sequence  CFPLDIRLKDGSLFWQSPKRPPSPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSA
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??
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   .........790.........800.........810.........820.........830.........840
Sequence  DALLNILSEVKIQEFKPSNKVVQTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKS
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?

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   .........850.........860.........870.........880.........890.........900
Sequence  DLQMAVLSFEKDDDHNGHIDFITAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTAT
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   .........910.........920.........930.........940.........950.........960
Sequence  VSGLVALEMIKVTGGYPFEAYKNCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTV
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   .........970.........980.........990.........1000.........1010.........1020
Sequence  HGKEDFTLLDFINAVKEKYGIEPTMVVQGVKMLYVPVMPGHAKRLKLTMHKLVKPTTEKK
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   .........1030.........1040.........1050..
Sequence  YVDLTVSFAPDIDGDEDLPGPPVRYYFSHDTD
Secondary structure 









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??













?????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3cmm chain A

3D model

Region: 38 - 1047
Aligned: 980
Modelled: 1010
Confidence: 100.0%
Identity: 43%
PDB header:ligase/protein binding
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of the uba1-ubiquitin complex

Phyre2

PDB 1y8q chain D

3D model

Region: 448 - 1043
Aligned: 495
Modelled: 514
Confidence: 100.0%
Identity: 28%
PDB header:ligase
Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex

Phyre2

PDB 3kyd chain B

3D model

Region: 448 - 1043
Aligned: 460
Modelled: 496
Confidence: 100.0%
Identity: 30%
PDB header:ligase
Chain: B: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic

Phyre2

PDB 3gzn chain B

3D model

Region: 452 - 1014
Aligned: 354
Modelled: 372
Confidence: 100.0%
Identity: 33%
PDB header:protein binding/ligase
Chain: B: PDB Molecule:nedd8-activating enzyme e1 catalytic subunit;
PDBTitle: structure of nedd8-activating enzyme in complex with nedd8 and mln4924

Phyre2

PDB 2nvu chain B

3D model

Region: 388 - 1040
Aligned: 425
Modelled: 450
Confidence: 100.0%
Identity: 31%
PDB header:protein turnover, ligase
Chain: B: PDB Molecule:maltose binding protein/nedd8-activating enzyme
PDBTitle: structure of appbp1-uba3~nedd8-nedd8-mgatp-ubc12(c111a), a2 trapped ubiquitin-like protein activation complex

Phyre2

PDB 1yov chain A domain 1

3D model

Region: 39 - 424
Aligned: 379
Modelled: 386
Confidence: 100.0%
Identity: 25%
Fold: Activating enzymes of the ubiquitin-like proteins
Superfamily: Activating enzymes of the ubiquitin-like proteins
Family: Ubiquitin activating enzymes (UBA)

Phyre2

PDB 1yov chain B domain 1

3D model

Region: 439 - 1005
Aligned: 352
Modelled: 368
Confidence: 100.0%
Identity: 33%
Fold: Activating enzymes of the ubiquitin-like proteins
Superfamily: Activating enzymes of the ubiquitin-like proteins
Family: Ubiquitin activating enzymes (UBA)

Phyre2

PDB 1y8q chain A

3D model

Region: 37 - 424
Aligned: 301
Modelled: 309
Confidence: 100.0%
Identity: 29%
PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-like 1 activating enzyme e1a;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex

Phyre2

PDB 1z7l chain C

3D model

Region: 622 - 889
Aligned: 255
Modelled: 268
Confidence: 100.0%
Identity: 40%
PDB header:ligase
Chain: C: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of fragment of mouse ubiquitin-activating2 enzyme

Phyre2

PDB 2px9 chain A

3D model

Region: 618 - 889
Aligned: 216
Modelled: 232
Confidence: 100.0%
Identity: 19%
PDB header:protein binding
Chain: A: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: the intrinsic affinity between e2 and the cys domain of e12 in ubiquitin-like modifications

Phyre2

PDB 3h9g chain A

3D model

Region: 381 - 613
Aligned: 222
Modelled: 227
Confidence: 100.0%
Identity: 22%
PDB header:transferase/antibiotic
Chain: A: PDB Molecule:mccb protein;
PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn

Phyre2

PDB 1jw9 chain B

3D model

Region: 442 - 624
Aligned: 173
Modelled: 177
Confidence: 100.0%
Identity: 25%
Fold: Activating enzymes of the ubiquitin-like proteins
Superfamily: Activating enzymes of the ubiquitin-like proteins
Family: Molybdenum cofactor biosynthesis protein MoeB

Phyre2

PDB 1zfn chain A

3D model

Region: 442 - 626
Aligned: 175
Modelled: 179
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase thif;
PDBTitle: structural analysis of escherichia coli thif

Phyre2

PDB 3vh3 chain A

3D model

Region: 448 - 626
Aligned: 173
Modelled: 179
Confidence: 100.0%
Identity: 20%
PDB header:metal binding protein/protein transport
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of atg7ctd-atg8 complex

Phyre2

PDB 3vh1 chain A

3D model

Region: 455 - 627
Aligned: 165
Modelled: 173
Confidence: 100.0%
Identity: 22%
PDB header:metal binding protein
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of saccharomyces cerevisiae atg7 (1-595)

Phyre2

PDB 3guc chain B

3D model

Region: 456 - 621
Aligned: 149
Modelled: 160
Confidence: 100.0%
Identity: 17%
PDB header:transferase
Chain: B: PDB Molecule:ubiquitin-like modifier-activating enzyme 5;
PDBTitle: human ubiquitin-activating enzyme 5 in complex with amppnp

Phyre2

PDB 2v31 chain A

3D model

Region: 198 - 308
Aligned: 111
Modelled: 111
Confidence: 99.9%
Identity: 44%
PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 x;
PDBTitle: structure of first catalytic cysteine half-domain of mouse2 ubiquitin-activating enzyme

Phyre2

PDB 3ong chain A

3D model

Region: 956 - 1044
Aligned: 86
Modelled: 89
Confidence: 97.7%
Identity: 19%
PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1-like;
PDBTitle: crystal structure of uba2ufd-ubc9: insights into e1-e2 interactions in2 sumo pathways

Phyre2

PDB 1pjq chain A domain 1

3D model

Region: 458 - 588
Aligned: 91
Modelled: 99
Confidence: 97.4%
Identity: 16%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Siroheme synthase N-terminal domain-like

Phyre2

PDB 2axq chain A

3D model

Region: 462 - 592
Aligned: 95
Modelled: 105
Confidence: 97.0%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae

Phyre2

PDB 1gpj chain A

3D model

Region: 4 - 187
Aligned: 140
Modelled: 140
Confidence: 96.4%
Identity: 19%
PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri

Phyre2
1

c3cmmA_
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c1y8qD_
3

c3kydB_
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c3gznB_
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c2nvuB_
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d1yova1
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d1yovb1
8

c1y8qA_
9

c1z7lC_
10

c2px9A_
11

c3h9gA_
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d1jw9b_
13

c1zfnA_
14

c3vh3A_
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c3vh1A_
16

c3gucB_
17

c2v31A_
18

c3ongA_
19

d1pjqa1
20

c2axqA_
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c1gpjA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3cmmA_



100.0 43 PDB header:ligase/protein binding
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of the uba1-ubiquitin complex
2c1y8qD_



100.0 28 PDB header:ligase
Chain: D: PDB Molecule:ubiquitin-like 2 activating enzyme e1b;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex
3c3kydB_



100.0 30 PDB header:ligase
Chain: B: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: human sumo e1~sumo1-amp tetrahedral intermediate mimic
4c3gznB_



100.0 33 PDB header:protein binding/ligase
Chain: B: PDB Molecule:nedd8-activating enzyme e1 catalytic subunit;
PDBTitle: structure of nedd8-activating enzyme in complex with nedd8 and mln4924
5c2nvuB_



100.0 31 PDB header:protein turnover, ligase
Chain: B: PDB Molecule:maltose binding protein/nedd8-activating enzyme
PDBTitle: structure of appbp1-uba3~nedd8-nedd8-mgatp-ubc12(c111a), a2 trapped ubiquitin-like protein activation complex
6d1yova1



100.0 25 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Ubiquitin activating enzymes (UBA)
7d1yovb1



100.0 33 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Ubiquitin activating enzymes (UBA)
8c1y8qA_



100.0 29 PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-like 1 activating enzyme e1a;
PDBTitle: sumo e1 activating enzyme sae1-sae2-mg-atp complex
9c1z7lC_



100.0 40 PDB header:ligase
Chain: C: PDB Molecule:ubiquitin-activating enzyme e1 1;
PDBTitle: crystal structure of fragment of mouse ubiquitin-activating2 enzyme
10c2px9A_



100.0 19 PDB header:protein binding
Chain: A: PDB Molecule:sumo-activating enzyme subunit 2;
PDBTitle: the intrinsic affinity between e2 and the cys domain of e12 in ubiquitin-like modifications
11c3h9gA_



100.0 22 PDB header:transferase/antibiotic
Chain: A: PDB Molecule:mccb protein;
PDBTitle: crystal structure of e. coli mccb + mcca-n7isoasn
12d1jw9b_



100.0 25 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Molybdenum cofactor biosynthesis protein MoeB
13c1zfnA_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:adenylyltransferase thif;
PDBTitle: structural analysis of escherichia coli thif
14c3vh3A_



100.0 20 PDB header:metal binding protein/protein transport
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of atg7ctd-atg8 complex
15c3vh1A_



100.0 22 PDB header:metal binding protein
Chain: A: PDB Molecule:ubiquitin-like modifier-activating enzyme atg7;
PDBTitle: crystal structure of saccharomyces cerevisiae atg7 (1-595)
16c3gucB_



100.0 17 PDB header:transferase
Chain: B: PDB Molecule:ubiquitin-like modifier-activating enzyme 5;
PDBTitle: human ubiquitin-activating enzyme 5 in complex with amppnp
17c2v31A_



99.9 44 PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1 x;
PDBTitle: structure of first catalytic cysteine half-domain of mouse2 ubiquitin-activating enzyme
18c3ongA_



97.7 19 PDB header:ligase
Chain: A: PDB Molecule:ubiquitin-activating enzyme e1-like;
PDBTitle: crystal structure of uba2ufd-ubc9: insights into e1-e2 interactions in2 sumo pathways
19d1pjqa1



97.4 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
20c2axqA_



97.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
21c3ic5A_



not modelled 96.9 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
22c1e5lA_



not modelled 96.9 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
23c2z2vA_



not modelled 96.5 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1688;
PDBTitle: crystal structure of l-lysine dehydrogenase from2 hyperthermophilic archaeon pyrococcus horikoshii
24d1vkna1



not modelled 96.4 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
25c1gpjA_



96.4 19 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
26c3dfzB_



not modelled 96.2 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
27d2naca1



not modelled 96.1 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
28c3hg7A_



not modelled 96.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-isomer specific 2-hydroxyacid dehydrogenase family
PDBTitle: crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase2 family protein from aeromonas salmonicida subsp. salmonicida a449
29c3gvxA_



not modelled 95.9 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerate dehydrogenase related protein;
PDBTitle: crystal structure of glycerate dehydrogenase related2 protein from thermoplasma acidophilum
30c1xdwA_



not modelled 95.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate
PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans
31c1dxyA_



not modelled 95.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-2-hydroxyisocaproate dehydrogenase;
PDBTitle: structure of d-2-hydroxyisocaproate dehydrogenase
32d1y8xb1



not modelled 95.8 13 Fold:Activating enzymes of the ubiquitin-like proteins
Superfamily:Activating enzymes of the ubiquitin-like proteins
Family:Ubiquitin activating enzymes (UBA)
33d2hjsa1



not modelled 95.7 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
34c1pjtB_



not modelled 95.7 15 PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis
35d1l7da1



not modelled 95.6 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
36d1lpfa2



not modelled 95.6 28 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
37c2gcgB_



not modelled 95.6 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase;
PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase
38c3pgjB_



not modelled 95.5 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate dehydrogenase;
PDBTitle: 2.49 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae o1 biovar eltor str. n169613 in complex with shikimate
39d1gtea4



not modelled 95.5 17 Fold:Nucleotide-binding domain
Superfamily:Nucleotide-binding domain
Family:N-terminal domain of adrenodoxin reductase-like
40d1gdha1



not modelled 95.5 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
41c2nloA_



not modelled 95.4 23 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase;
PDBTitle: crystal structure of the quinate dehydrogenase from corynebacterium2 glutamicum
42d2gz1a1



not modelled 95.4 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
43c1vi2B_



not modelled 95.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate 5-dehydrogenase 2;
PDBTitle: crystal structure of shikimate-5-dehydrogenase with nad
44d1vi2a1



not modelled 95.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
45c1qp8A_



not modelled 95.3 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:formate dehydrogenase;
PDBTitle: crystal structure of a putative formate dehydrogenase from2 pyrobaculum aerophilum
46c1vknC_



not modelled 95.3 22 PDB header:oxidoreductase
Chain: C: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase;
PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (tm1782) from thermotoga maritima at 1.80 a resolution
47c2yv3B_



not modelled 95.3 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase from thermus2 thermophilus hb8
48d3lada2



not modelled 95.2 29 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
49d2dlda1



not modelled 95.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
50d1f0ya2



not modelled 95.2 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
51d1ebda2



not modelled 95.1 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
52d1e5qa1



not modelled 95.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
53c2g76A_



not modelled 95.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
54c2qz9B_



not modelled 94.9 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: crystal structure of aspartate semialdehyde dehydrogenase2 ii from vibrio cholerae
55c2cukC_



not modelled 94.9 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase;
PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8
56d2q49a1



not modelled 94.9 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
57d1qp8a1



not modelled 94.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
58d1dxya1



not modelled 94.8 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
59d1wdka3



not modelled 94.8 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
60c3eywA_



not modelled 94.8 16 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
61d1h6va2



not modelled 94.7 21 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
62d1j4aa1



not modelled 94.7 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
63c2ep5B_



not modelled 94.7 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:350aa long hypothetical aspartate-semialdehyde
PDBTitle: structural study of project id st1242 from sulfolobus tokodaii strain7
64d1ygya1



not modelled 94.6 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
65c1z82A_



not modelled 94.6 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase;
PDBTitle: crystal structure of glycerol-3-phosphate dehydrogenase (tm0378) from2 thermotoga maritima at 2.00 a resolution
66c1j4aA_



not modelled 94.5 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus
67c2ofpB_



not modelled 94.5 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketopantoate reductase;
PDBTitle: crystal structure of escherichia coli ketopantoate2 reductase in a ternary complex with nadp+ and pantoate
68c1pzfD_



not modelled 94.5 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:lactate dehydrogenase;
PDBTitle: t.gondii ldh1 ternary complex with apad+ and oxalate
69c3pwzA_



not modelled 94.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase 3;
PDBTitle: crystal structure of an ael1 enzyme from pseudomonas putida
70c3oetF_



not modelled 94.4 15 PDB header:oxidoreductase
Chain: F: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: d-erythronate-4-phosphate dehydrogenase complexed with nad
71d1mx3a1



not modelled 94.4 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
72c1wwkA_



not modelled 94.4 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3
73d1pzga1



not modelled 94.4 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
74d1gesa2



not modelled 94.3 17 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
75d1gpja2



not modelled 94.3 26 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
76c1gdhA_



not modelled 94.3 16 PDB header:oxidoreductase(choh (d)-nad(p)+ (a))
Chain: A: PDB Molecule:d-glycerate dehydrogenase;
PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution
77c3evtA_



not modelled 94.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum
78c3kboB_



not modelled 94.2 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a;
PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp
79d1kyqa1



not modelled 94.2 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
80d1onfa2



not modelled 94.2 27 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
81c2qx7A_



not modelled 94.1 21 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
82c3n7uD_



not modelled 94.1 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
83d1i24a_



not modelled 94.1 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
84c2eklA_



not modelled 94.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: structure of st1218 protein from sulfolobus tokodaii
85d1pjca1



not modelled 94.1 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
86c2dbqA_



not modelled 94.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
87c2omeA_



not modelled 94.0 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:c-terminal-binding protein 2;
PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h)
88d1v59a2



not modelled 93.9 37 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
89c1ldbA_



not modelled 93.9 18 PDB header:oxidoreductase(choh(d)-nad(a))
Chain: A: PDB Molecule:apo-l-lactate dehydrogenase;
PDBTitle: structure determination and refinement of bacillus2 stearothermophilus lactate dehydrogenase
90c3k96B_



not modelled 93.7 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
91c2hjrK_



not modelled 93.7 14 PDB header:oxidoreductase
Chain: K: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of cryptosporidium parvum malate2 dehydrogenase
92c3bazA_



not modelled 93.7 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
93c2j6iC_



not modelled 93.7 19 PDB header:oxidoreductase
Chain: C: PDB Molecule:formate dehydrogenase;
PDBTitle: candida boidinii formate dehydrogenase (fdh) c-terminal2 mutant
94d2nu7a1



not modelled 93.7 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:CoA-binding domain
95d1uxja1



not modelled 93.6 28 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
96c4dioB_



not modelled 93.6 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:nad(p) transhydrogenase subunit alpha part 1;
PDBTitle: the crystal structure of transhydrogenase from sinorhizobium meliloti
97c3d0oA_



not modelled 93.5 25 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-lactate dehydrogenase 1;
PDBTitle: crystal structure of lactate dehydrogenase from2 staphylococcus aureus
98c2w2kB_



not modelled 93.5 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-mandelate dehydrogenase;
PDBTitle: crystal structure of the apo forms of rhodotorula graminis2 d-mandelate dehydrogenase at 1.8a.
99d1nhpa1



not modelled 93.5 15 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
100c2d0iC_



not modelled 93.5 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure ph0520 protein from pyrococcus horikoshii ot3
101d1nvta1



not modelled 93.4 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
102c1zcjA_



not modelled 93.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:peroxisomal bifunctional enzyme;
PDBTitle: crystal structure of 3-hydroxyacyl-coa dehydrogenase
103d1mv8a2



not modelled 93.4 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
104c2fnzA_



not modelled 93.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:lactate dehydrogenase;
PDBTitle: crystal structure of the lactate dehydrogenase from cryptosporidium2 parvum complexed with cofactor (b-nicotinamide adenine dinucleotide)3 and inhibitor (oxamic acid)
105d2f1ka2



not modelled 93.4 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
106c2ozpA_



not modelled 93.4 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-acetyl-gamma-glutamyl-phosphate reductase;
PDBTitle: crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase2 (ttha1904) from thermus thermophilus
107d1m6ia2



not modelled 93.4 16 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
108d1xhca2



not modelled 93.4 24 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
109c1ys4A_



not modelled 93.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:aspartate-semialdehyde dehydrogenase;
PDBTitle: structure of aspartate-semialdehyde dehydrogenase from2 methanococcus jannaschii
110c3o8qB_



not modelled 93.3 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:shikimate 5-dehydrogenase i alpha;
PDBTitle: 1.45 angstrom resolution crystal structure of shikimate 5-2 dehydrogenase (aroe) from vibrio cholerae
111d1hyea1



not modelled 93.3 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
112c1zejA_



not modelled 93.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the 3-hydroxyacyl-coa dehydrogenase (hbd-9,2 af2017) from archaeoglobus fulgidus dsm 4304 at 2.00 a resolution
113c3tozA_



not modelled 93.3 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:shikimate dehydrogenase;
PDBTitle: 2.2 angstrom crystal structure of shikimate 5-dehydrogenase from2 listeria monocytogenes in complex with nad.
114c3gg9C_



not modelled 93.2 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase oxidoreductase protein;
PDBTitle: crystal structure of putative d-3-phosphoglycerate dehydrogenase2 oxidoreductase from ralstonia solanacearum
115d3grsa2



not modelled 93.2 23 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
116d1d7ya2



not modelled 93.2 26 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
117d1gera2



not modelled 93.1 23 Fold:FAD/NAD(P)-binding domain
Superfamily:FAD/NAD(P)-binding domain
Family:FAD/NAD-linked reductases, N-terminal and central domains
118c1vl6C_



not modelled 93.1 26 PDB header:oxidoreductase
Chain: C: PDB Molecule:malate oxidoreductase;
PDBTitle: crystal structure of nad-dependent malic enzyme (tm0542) from2 thermotoga maritima at 2.61 a resolution
119c1drwA_



not modelled 93.1 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:dihydrodipicolinate reductase;
PDBTitle: escherichia coli dhpr/nhdh complex
120c2hjsA_



not modelled 93.1 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:usg-1 protein homolog;
PDBTitle: the structure of a probable aspartate-semialdehyde dehydrogenase from2 pseudomonas aeruginosa

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