Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0C0R7
DateWed Jan 25 15:20:35 GMT 2012
Unique Job IDe41077afe0f0a17f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d1ej0a_
Top template information
Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:RNA methyltransferase FtsJ
Confidence and coverage
Confidence:100.0% Coverage: 86%
180 residues ( 86% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGA
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Disorder  ?????????







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??
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   .........70.........80.........90.........100.........110.........120
Sequence  APGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQV
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   .........130.........140.........150.........160.........170.........180
Sequence  VMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRS
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Disorder 





?




















































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   .........190.........200.........
Sequence  LFTKVKVRKPDSSRARSREVYIVATGRKP
Secondary structure 















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Disorder 






















??????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1ej0 chain A

3D model

Region: 30 - 209
Aligned: 180
Modelled: 180
Confidence: 100.0%
Identity: 100%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: RNA methyltransferase FtsJ

Phyre2

PDB 2nyu chain A

3D model

Region: 31 - 208
Aligned: 170
Modelled: 178
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2;
PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine

Phyre2

PDB 2plw chain A

3D model

Region: 31 - 208
Aligned: 173
Modelled: 178
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative;
PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).

Phyre2

PDB 3dou chain A

3D model

Region: 31 - 208
Aligned: 169
Modelled: 178
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j;
PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1

Phyre2

PDB 2wa1 chain A

3D model

Region: 10 - 208
Aligned: 190
Modelled: 199
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)

Phyre2

PDB 2px2 chain B

3D model

Region: 3 - 209
Aligned: 196
Modelled: 202
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c
PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)

Phyre2

PDB 2p3q chain A

3D model

Region: 3 - 209
Aligned: 197
Modelled: 203
Confidence: 100.0%
Identity: 19%
PDB header:viral protein,transferase
Chain: A: PDB Molecule:type ii methyltransferase;
PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine

Phyre2

PDB 3lkz chain B

3D model

Region: 3 - 209
Aligned: 197
Modelled: 206
Confidence: 100.0%
Identity: 21%
PDB header:viral protein
Chain: B: PDB Molecule:non-structural protein 5;
PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase

Phyre2

PDB 3gcz chain A

3D model

Region: 15 - 209
Aligned: 184
Modelled: 195
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:polyprotein;
PDBTitle: yokose virus methyltransferase in complex with adomet

Phyre2

PDB 2p41 chain A domain 1

3D model

Region: 16 - 209
Aligned: 183
Modelled: 183
Confidence: 100.0%
Identity: 17%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: mRNA cap methylase

Phyre2

PDB 3eva chain A

3D model

Region: 3 - 209
Aligned: 196
Modelled: 205
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase ns5;
PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine

Phyre2

PDB 3opn chain A

3D model

Region: 31 - 208
Aligned: 162
Modelled: 162
Confidence: 99.9%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis

Phyre2

PDB 2frx chain D

3D model

Region: 50 - 209
Aligned: 153
Modelled: 160
Confidence: 99.9%
Identity: 20%
PDB header:transferase
Chain: D: PDB Molecule:hypothetical protein yebu;
PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli

Phyre2

PDB 3m6w chain A

3D model

Region: 49 - 209
Aligned: 160
Modelled: 161
Confidence: 99.8%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine

Phyre2

PDB 3hp7 chain A

3D model

Region: 19 - 209
Aligned: 170
Modelled: 177
Confidence: 99.8%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.

Phyre2

PDB 3m4x chain A

3D model

Region: 49 - 209
Aligned: 158
Modelled: 161
Confidence: 99.8%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:nol1/nop2/sun family protein;
PDBTitle: structure of a ribosomal methyltransferase

Phyre2

PDB 2yxl chain A

3D model

Region: 50 - 208
Aligned: 153
Modelled: 153
Confidence: 99.8%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851

Phyre2

PDB 1ixk chain A

3D model

Region: 49 - 191
Aligned: 135
Modelled: 143
Confidence: 99.8%
Identity: 23%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: NOL1/NOP2/sun

Phyre2

PDB 3ely chain A

3D model

Region: 3 - 203
Aligned: 193
Modelled: 201
Confidence: 99.7%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: wesselsbron virus methyltransferase in complex with adohcy

Phyre2

PDB 1sqg chain A

3D model

Region: 49 - 208
Aligned: 150
Modelled: 154
Confidence: 99.7%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution

Phyre2
1

d1ej0a_
2

c2nyuA_
3

c2plwA_
4

c3douA_
5

c2wa1A_
6

c2px2B_
7

c2p3qA_
8

c3lkzB_
9

c3gczA_
10

d2p41a1
11

c3evaA_
12

c3opnA_
13

c2frxD_
14

c3m6wA_
15

c3hp7A_
16

c3m4xA_
17

c2yxlA_
18

d1ixka_
19

c3elyA_
20

c1sqgA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d1ej0a_



100.0 100 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:RNA methyltransferase FtsJ
2c2nyuA_



100.0 37 PDB header:transferase
Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2;
PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine
3c2plwA_



100.0 29 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative;
PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).
4c3douA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j;
PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1
5c2wa1A_



100.0 21 PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)
6c2px2B_



100.0 18 PDB header:transferase
Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c
PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)
7c2p3qA_



100.0 19 PDB header:viral protein,transferase
Chain: A: PDB Molecule:type ii methyltransferase;
PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine
8c3lkzB_



100.0 21 PDB header:viral protein
Chain: B: PDB Molecule:non-structural protein 5;
PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase
9c3gczA_



100.0 22 PDB header:transferase
Chain: A: PDB Molecule:polyprotein;
PDBTitle: yokose virus methyltransferase in complex with adomet
10d2p41a1



100.0 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap methylase
11c3evaA_



100.0 20 PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase ns5;
PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine
12c3opnA_



99.9 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
13c2frxD_



99.9 20 PDB header:transferase
Chain: D: PDB Molecule:hypothetical protein yebu;
PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli
14c3m6wA_



99.8 21 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine
15c3hp7A_



99.8 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.
16c3m4xA_



99.8 20 PDB header:transferase
Chain: A: PDB Molecule:nol1/nop2/sun family protein;
PDBTitle: structure of a ribosomal methyltransferase
17c2yxlA_



99.8 31 PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851
18d1ixka_



99.8 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
19c3elyA_



99.7 17 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: wesselsbron virus methyltransferase in complex with adohcy
20c1sqgA_



99.7 22 PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution
21c2oxtC_



not modelled 99.7 21 PDB header:viral protein
Chain: C: PDB Molecule:nucleoside-2'-o-methyltransferase;
PDBTitle: crystal structure of meaban virus nucleoside-2'-o-2 methyltransferase
22c3a4tA_



not modelled 99.7 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase mj0026;
PDBTitle: crystal structure of atrm4 from m.jannaschii with sinefungin
23d1wg8a2



not modelled 99.6 27 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
24d1sqga2



not modelled 99.6 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
25c3eeyJ_



not modelled 99.6 21 PDB header:transferase
Chain: J: PDB Molecule:putative rrna methylase;
PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum
26d1m6ya2



not modelled 99.6 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
27d2b9ea1



not modelled 99.5 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
28d1g8aa_



not modelled 99.5 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
29c2ipxA_



not modelled 99.5 20 PDB header:transferase
Chain: A: PDB Molecule:rrna 2'-o-methyltransferase fibrillarin;
PDBTitle: human fibrillarin
30c3id5F_



not modelled 99.5 20 PDB header:transferase/ribosomal protein/rna
Chain: F: PDB Molecule:fibrillarin-like rrna/trna 2'-o-methyltransferase;
PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna
31d1prya_



not modelled 99.4 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
32c3bkxB_



not modelled 99.4 15 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution
33d2as0a2



not modelled 99.4 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
34d1yb2a1



not modelled 99.4 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
35c1yb2A_



not modelled 99.4 17 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ta0852;
PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
36c3mtiA_



not modelled 99.4 13 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
37d1o54a_



not modelled 99.4 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
38d1i9ga_



not modelled 99.4 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
39c3mb5A_



not modelled 99.4 23 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine
40d1g8sa_



not modelled 99.4 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
41d2b78a2



not modelled 99.3 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
42c2as0A_



not modelled 99.3 20 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ph1915;
PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase
43c2ozvA_



not modelled 99.3 15 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein atu0636;
PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens.
44d1nt2a_



not modelled 99.3 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
45c3g5tA_



not modelled 99.3 17 PDB header:transferase
Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase;
PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
46c2yvlB_



not modelled 99.3 19 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
47c2b78A_



not modelled 99.3 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein smu.776;
PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans
48c2fk8A_



not modelled 99.3 22 PDB header:transferase
Chain: A: PDB Molecule:methoxy mycolic acid synthase 4;
PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
49d1wxxa2



not modelled 99.3 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
50d1yzha1



not modelled 99.3 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
51d2fk8a1



not modelled 99.3 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
52d1l1ea_



not modelled 99.3 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
53c3e05B_



not modelled 99.3 16 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating);
PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
54d1kpia_



not modelled 99.3 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
55c2pwyB_



not modelled 99.3 23 PDB header:transferase
Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase;
PDBTitle: crystal structure of a m1a58 trna methyltransferase
56d2b3ta1



not modelled 99.3 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
57d1kpga_



not modelled 99.3 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
58c1wxwA_



not modelled 99.2 19 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha1280;
PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8
59c3ujcA_



not modelled 99.2 14 PDB header:transferase
Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase;
PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine
60d1tpya_



not modelled 99.2 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
61c3bgvC_



not modelled 99.2 18 PDB header:transferase
Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase;
PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah
62c3c0kB_



not modelled 99.2 16 PDB header:transferase
Chain: B: PDB Molecule:upf0064 protein yccw;
PDBTitle: crystal structure of a ribosomal rna methyltranferase
63c3lpmA_



not modelled 99.2 16 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes
64d1l3ia_



not modelled 99.2 21 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Precorrin-6Y methyltransferase (CbiT)
65c3ofkA_



not modelled 99.2 14 PDB header:transferase
Chain: A: PDB Molecule:nodulation protein s;
PDBTitle: crystal structure of n-methyltransferase nods from bradyrhizobium2 japonicum wm9 in complex with s-adenosyl-l-homocysteine (sah)
66c3ku1E_



not modelled 99.2 15 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
67d1i1na_



not modelled 99.2 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
68d2b25a1



not modelled 99.2 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
69c3grzA_



not modelled 99.2 15 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase;
PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
70c1wg8B_



not modelled 99.2 30 PDB header:transferase
Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent
PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8.
71d1dusa_



not modelled 99.2 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein MJ0882
72c3lecA_



not modelled 99.1 15 PDB header:structure genomics, unknown function
Chain: A: PDB Molecule:nadb-rossmann superfamily protein;
PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
73d1dl5a1



not modelled 99.1 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
74d2nxca1



not modelled 99.1 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ribosomal protein L11 methyltransferase PrmA
75d1jqea_



not modelled 99.1 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Histamine methyltransferase
76c3e23A_



not modelled 99.1 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein rpa2492;
PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299
77d1xcla_



not modelled 99.1 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
78c3a26A_



not modelled 99.1 19 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein ph0793;
PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado
79c3ggdA_



not modelled 99.1 12 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of sam-dependent methyltransferase (yp_325210.1)2 from anabaena variabilis atcc 29413 at 2.11 a resolution
80d1ve3a1



not modelled 99.1 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
81c1m6yA_



not modelled 99.1 24 PDB header:transferase
Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw;
PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah
82c3hm2G_



not modelled 99.1 13 PDB header:transferase
Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase;
PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae
83d2o57a1



not modelled 99.1 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
84d2igta1



not modelled 99.1 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
85c3e7pA_



not modelled 99.1 24 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of of putative methyltransferase from bacteroides2 vulgatus atcc 8482
86d1nkva_



not modelled 99.1 24 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical Protein YjhP
87c3evzA_



not modelled 99.1 12 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus
88d1nv8a_



not modelled 99.1 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK
89c3gnlB_



not modelled 99.1 14 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472;
PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
90d2gh1a1



not modelled 99.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:BC2162-like
91c3dliB_



not modelled 99.1 15 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of a sam dependent methyltransferase from2 archaeoglobus fulgidus
92c3ccfB_



not modelled 99.1 17 PDB header:transferase
Chain: B: PDB Molecule:cyclopropane-fatty-acyl-phospholipid synthase;
PDBTitle: crystal structure of putative methyltransferase (yp_321342.1) from2 anabaena variabilis atcc 29413 at 1.90 a resolution
93d2frna1



not modelled 99.1 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Met-10+ protein-like
94d2fcaa1



not modelled 99.1 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TrmB-like
95c1z3cA_



not modelled 99.0 23 PDB header:transferase
Chain: A: PDB Molecule:mrna capping enzyme;
PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet
96d1ri5a_



not modelled 99.0 23 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap (Guanine N-7) methyltransferase
97c3ocjA_



not modelled 99.0 12 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative exported protein;
PDBTitle: the crystal structure of a possilbe exported protein from bordetella2 parapertussis
98c3dmgA_



not modelled 99.0 17 PDB header:transferase
Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase;
PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy
99c3f4kA_



not modelled 99.0 20 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a probable methyltransferase from2 bacteroides thetaiotaomicron. northeast structural3 genomics target btr309.
100c1dl5A_



not modelled 99.0 23 PDB header:transferase
Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: protein-l-isoaspartate o-methyltransferase
101d1zx0a1



not modelled 99.0 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
102c3njrB_



not modelled 99.0 16 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y methylase;
PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus
103d2ex4a1



not modelled 99.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
104c2yxeB_



not modelled 99.0 22 PDB header:transferase
Chain: B: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: crystal structure of l-isoaspartyl protein carboxyl methyltranferase
105c3dxyA_



not modelled 99.0 9 PDB header:transferase
Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase;
PDBTitle: crystal structure of ectrmb in complex with sam
106c3h2bB_



not modelled 99.0 20 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of the sam-dependent methyltransferase2 cg3271 from corynebacterium glutamicum in complex with s-3 adenosyl-l-homocysteine and pyrophosphate. northeast4 structural genomics consortium target cgr113a
107d1r18a_



not modelled 99.0 25 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
108c2pbfA_



not modelled 99.0 14 PDB header:transferase
Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase beta-aspartate
PDBTitle: crystal structure of a putative protein-l-isoaspartate o-2 methyltransferase beta-aspartate methyltransferase (pcmt) from3 plasmodium falciparum in complex with s-adenosyl-l-homocysteine
109c3a27A_



not modelled 99.0 16 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet
110d1p1ca_



not modelled 99.0 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Guanidinoacetate methyltransferase
111d1xxla_



not modelled 99.0 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
112c2yx1A_



not modelled 99.0 22 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein mj0883;
PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase
113c2yxdA_



not modelled 99.0 16 PDB header:transferase
Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase
PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit)
114c3duwB_



not modelled 99.0 14 PDB header:transferase
Chain: B: PDB Molecule:o-methyltransferase, putative;
PDBTitle: crystal structural analysis of the o-methyltransferase from2 bacillus cereus in complex sah
115c2yr0A_



not modelled 99.0 22 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha0223;
PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8
116c3cc8A_



not modelled 99.0 13 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a putative methyltransferase (bce_1332) from2 bacillus cereus atcc 10987 at 1.64 a resolution
117d1r74a_



not modelled 99.0 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glycine N-methyltransferase
118c1vl5B_



not modelled 99.0 19 PDB header:transferase
Chain: B: PDB Molecule:unknown conserved protein bh2331;
PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution
119d1y8ca_



not modelled 99.0 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
120c2pjdA_



not modelled 99.0 14 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c;
PDBTitle: crystal structure of 16s rrna methyltransferase rsmc

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0