Phyre 2 Results for P0C0R7

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Email | l.a.kelley@imperial.ac.uk
Description | P0C0R7
Date | Wed Jan 25 15:20:35 GMT 2012
Unique Job ID | e41077afe0f0a17f

Summary |

Top model
Image coloured by rainbow N → C terminus
| Close Jmol

Model (left) based on template d1ej0a_
Top template information
Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:RNA methyltransferase FtsJ
Confidence and coverage
Confidence: | 100.0% | Coverage: | 86%
180 residues ( 86% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis |

Secondary structure and disorder prediction |

|  | 1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60
Sequence |  | M | T | G | K | K | R | S | A | S | S | S | R | W | L | Q | E | H | F | S | D | K | Y | V | Q | Q | A | Q | K | K | G | L | R | S | R | A | W | F | K | L | D | E | I | Q | Q | S | D | K | L | F | K | P | G | M | T | V | V | D | L | G | A
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  | ? | ? | ? | ? | ? | ? | ? | ? | ? |  |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  | ? | ? |  | ? | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120
Sequence |  | A | P | G | G | W | S | Q | Y | V | V | T | Q | I | G | G | K | G | R | I | I | A | C | D | L | L | P | M | D | P | I | V | G | V | D | F | L | Q | G | D | F | R | D | E | L | V | M | K | A | L | L | E | R | V | G | D | S | K | V | Q | V
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180
Sequence |  | V | M | S | D | M | A | P | N | M | S | G | T | P | A | V | D | I | P | R | A | M | Y | L | V | E | L | A | L | E | M | C | R | D | V | L | A | P | G | G | S | F | V | V | K | V | F | Q | G | E | G | F | D | E | Y | L | R | E | I | R | S
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  | ? |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | .
Sequence |  | L | F | T | K | V | K | V | R | K | P | D | S | S | R | A | R | S | R | E | V | Y | I | V | A | T | G | R | K | P
Secondary structure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
SS confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | ? | ? | ? | ? | ? | ?
Disorder confidence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |

Confidence Key
High(9) |  |  |  |  |  |  |  |  |  |  | Low (0)

? | Disordered
| Alpha helix
| Beta strand

Domain analysis |

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank | Aligned region
--- | ---
1 |
| d1ej0a_ |

### PDB 1ej0 chain A

Region: 30 - 209
Aligned: 180
Modelled: 180
Confidence: 100.0%
Identity: 100%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: RNA methyltransferase FtsJ

Phyre2
2 |
| c2nyuA_ |

### PDB 2nyu chain A

Region: 31 - 208
Aligned: 170
Modelled: 178
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2;
PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine

Phyre2
3 |
| c2plwA_ |

### PDB 2plw chain A

Region: 31 - 208
Aligned: 173
Modelled: 178
Confidence: 100.0%
Identity: 29%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative;
PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).

Phyre2
4 |
| c3douA_ |

### PDB 3dou chain A

Region: 31 - 208
Aligned: 169
Modelled: 178
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j;
PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1

Phyre2
5 |
| c2wa1A_ |

### PDB 2wa1 chain A

Region: 10 - 208
Aligned: 190
Modelled: 199
Confidence: 100.0%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)

Phyre2
6 |
| c2px2B_ |

### PDB 2px2 chain B

Region: 3 - 209
Aligned: 196
Modelled: 202
Confidence: 100.0%
Identity: 18%
PDB header:transferase
Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c
PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)

Phyre2
7 |
| c2p3qA_ |

### PDB 2p3q chain A

Region: 3 - 209
Aligned: 197
Modelled: 203
Confidence: 100.0%
Identity: 19%
PDB header:viral protein,transferase
Chain: A: PDB Molecule:type ii methyltransferase;
PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine

Phyre2
8 |
| c3lkzB_ |

### PDB 3lkz chain B

Region: 3 - 209
Aligned: 197
Modelled: 206
Confidence: 100.0%
Identity: 21%
PDB header:viral protein
Chain: B: PDB Molecule:non-structural protein 5;
PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase

Phyre2
9 |
| c3gczA_ |

### PDB 3gcz chain A

Region: 15 - 209
Aligned: 184
Modelled: 195
Confidence: 100.0%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:polyprotein;
PDBTitle: yokose virus methyltransferase in complex with adomet

Phyre2
10 |
| d2p41a1 |

### PDB 2p41 chain A domain 1

Region: 16 - 209
Aligned: 183
Modelled: 183
Confidence: 100.0%
Identity: 17%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: mRNA cap methylase

Phyre2
11 |
| c3evaA_ |

### PDB 3eva chain A

Region: 3 - 209
Aligned: 196
Modelled: 205
Confidence: 100.0%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase ns5;
PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine

Phyre2
12 |
| c3opnA_ |

### PDB 3opn chain A

Region: 31 - 208
Aligned: 162
Modelled: 162
Confidence: 99.9%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis

Phyre2
13 |
| c2frxD_ |

### PDB 2frx chain D

Region: 50 - 209
Aligned: 153
Modelled: 160
Confidence: 99.9%
Identity: 20%
PDB header:transferase
Chain: D: PDB Molecule:hypothetical protein yebu;
PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli

Phyre2
14 |
| c3m6wA_ |

### PDB 3m6w chain A

Region: 49 - 209
Aligned: 160
Modelled: 161
Confidence: 99.8%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine

Phyre2
15 |
| c3hp7A_ |

### PDB 3hp7 chain A

Region: 19 - 209
Aligned: 170
Modelled: 177
Confidence: 99.8%
Identity: 17%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.

Phyre2
16 |
| c3m4xA_ |

### PDB 3m4x chain A

Region: 49 - 209
Aligned: 158
Modelled: 161
Confidence: 99.8%
Identity: 20%
PDB header:transferase
Chain: A: PDB Molecule:nol1/nop2/sun family protein;
PDBTitle: structure of a ribosomal methyltransferase

Phyre2
17 |
| c2yxlA_ |

### PDB 2yxl chain A

Region: 50 - 208
Aligned: 153
Modelled: 153
Confidence: 99.8%
Identity: 31%
PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851

Phyre2
18 |
| d1ixka_ |

### PDB 1ixk chain A

Region: 49 - 191
Aligned: 135
Modelled: 143
Confidence: 99.8%
Identity: 23%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: NOL1/NOP2/sun

Phyre2
19 |
| c3elyA_ |

### PDB 3ely chain A

Region: 3 - 203
Aligned: 193
Modelled: 201
Confidence: 99.7%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: wesselsbron virus methyltransferase in complex with adohcy

Phyre2
20 |
| c1sqgA_ |

### PDB 1sqg chain A

Region: 49 - 208
Aligned: 150
Modelled: 154
Confidence: 99.7%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution

Phyre2
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Detailed template information |

# | Template | Alignment Coverage | 3D Model | Confidence | % i.d. | Template Information
--- | --- | --- | --- | --- | --- | ---
1 | d1ej0a_ |
|  | 100.0 | 100 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:RNA methyltransferase FtsJ
2 | c2nyuA_ |
|  | 100.0 | 37 | PDB header:transferase Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2; PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine
3 | c2plwA_ |
|  | 100.0 | 29 | PDB header:transferase Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative; PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).
4 | c3douA_ |
|  | 100.0 | 33 | PDB header:transferase Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j; PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1
5 | c2wa1A_ |
|  | 100.0 | 21 | PDB header:transferase Chain: A: PDB Molecule:non-structural protein 5; PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)
6 | c2px2B_ |
|  | 100.0 | 18 | PDB header:transferase Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)
7 | c2p3qA_ |
|  | 100.0 | 19 | PDB header:viral protein,transferase Chain: A: PDB Molecule:type ii methyltransferase; PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine
8 | c3lkzB_ |
|  | 100.0 | 21 | PDB header:viral protein Chain: B: PDB Molecule:non-structural protein 5; PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase
9 | c3gczA_ |
|  | 100.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:polyprotein; PDBTitle: yokose virus methyltransferase in complex with adomet
10 | d2p41a1 |
|  | 100.0 | 17 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:mRNA cap methylase
11 | c3evaA_ |
|  | 100.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:rna-directed rna polymerase ns5; PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine
12 | c3opnA_ |
|  | 99.9 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative hemolysin; PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
13 | c2frxD_ |
|  | 99.9 | 20 | PDB header:transferase Chain: D: PDB Molecule:hypothetical protein yebu; PDBTitle: crystal structure of yebu, a m5c rna methyltransferase from e.coli
14 | c3m6wA_ |
|  | 99.8 | 21 | PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: multi-site-specific 16s rrna methyltransferase rsmf from thermus2 thermophilus in space group p21212 in complex with s-adenosyl-l-3 methionine
15 | c3hp7A_ |
|  | 99.8 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hemolysin, putative; PDBTitle: putative hemolysin from streptococcus thermophilus.
16 | c3m4xA_ |
|  | 99.8 | 20 | PDB header:transferase Chain: A: PDB Molecule:nol1/nop2/sun family protein; PDBTitle: structure of a ribosomal methyltransferase
17 | c2yxlA_ |
|  | 99.8 | 31 | PDB header:transferase Chain: A: PDB Molecule:450aa long hypothetical fmu protein; PDBTitle: crystal structure of ph0851
18 | d1ixka_ |
|  | 99.8 | 23 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun
19 | c3elyA_ |
|  | 99.7 | 17 | PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: wesselsbron virus methyltransferase in complex with adohcy
20 | c1sqgA_ |
|  | 99.7 | 22 | PDB header:transferase Chain: A: PDB Molecule:sun protein; PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution
21 | c2oxtC_ |
| not modelled | 99.7 | 21 | PDB header:viral protein Chain: C: PDB Molecule:nucleoside-2'-o-methyltransferase; PDBTitle: crystal structure of meaban virus nucleoside-2'-o-2 methyltransferase
22 | c3a4tA_ |
| not modelled | 99.7 | 16 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase mj0026; PDBTitle: crystal structure of atrm4 from m.jannaschii with sinefungin
23 | d1wg8a2 |
| not modelled | 99.6 | 27 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:MraW-like putative methyltransferases
24 | d1sqga2 |
| not modelled | 99.6 | 20 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun
25 | c3eeyJ_ |
| not modelled | 99.6 | 21 | PDB header:transferase Chain: J: PDB Molecule:putative rrna methylase; PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum
26 | d1m6ya2 |
| not modelled | 99.6 | 22 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:MraW-like putative methyltransferases
27 | d2b9ea1 |
| not modelled | 99.5 | 19 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:NOL1/NOP2/sun
28 | d1g8aa_ |
| not modelled | 99.5 | 25 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue
29 | c2ipxA_ |
| not modelled | 99.5 | 20 | PDB header:transferase Chain: A: PDB Molecule:rrna 2'-o-methyltransferase fibrillarin; PDBTitle: human fibrillarin
30 | c3id5F_ |
| not modelled | 99.5 | 20 | PDB header:transferase/ribosomal protein/rna Chain: F: PDB Molecule:fibrillarin-like rrna/trna 2'-o-methyltransferase; PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna
31 | d1prya_ |
| not modelled | 99.4 | 21 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue
32 | c3bkxB_ |
| not modelled | 99.4 | 15 | PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution
33 | d2as0a2 |
| not modelled | 99.4 | 21 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase
34 | d1yb2a1 |
| not modelled | 99.4 | 17 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like
35 | c1yb2A_ |
| not modelled | 99.4 | 17 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ta0852; PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
36 | c3mtiA_ |
| not modelled | 99.4 | 13 | PDB header:transferase Chain: A: PDB Molecule:rrna methylase; PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
37 | d1o54a_ |
| not modelled | 99.4 | 23 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like
38 | d1i9ga_ |
| not modelled | 99.4 | 20 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like
39 | c3mb5A_ |
| not modelled | 99.4 | 23 | PDB header:transferase Chain: A: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine
40 | d1g8sa_ |
| not modelled | 99.4 | 17 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue
41 | d2b78a2 |
| not modelled | 99.3 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase
42 | c2as0A_ |
| not modelled | 99.3 | 20 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ph1915; PDBTitle: crystal structure of ph1915 (apc 5817): a hypothetical rna2 methyltransferase
43 | c2ozvA_ |
| not modelled | 99.3 | 15 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein atu0636; PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens.
44 | d1nt2a_ |
| not modelled | 99.3 | 21 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Fibrillarin homologue
45 | c3g5tA_ |
| not modelled | 99.3 | 17 | PDB header:transferase Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase; PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
46 | c2yvlB_ |
| not modelled | 99.3 | 19 | PDB header:transferase Chain: B: PDB Molecule:hypothetical protein; PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
47 | c2b78A_ |
| not modelled | 99.3 | 16 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein smu.776; PDBTitle: a putative sam-dependent methyltransferase from2 streptococcus mutans
48 | c2fk8A_ |
| not modelled | 99.3 | 22 | PDB header:transferase Chain: A: PDB Molecule:methoxy mycolic acid synthase 4; PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
49 | d1wxxa2 |
| not modelled | 99.3 | 18 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase
50 | d1yzha1 |
| not modelled | 99.3 | 14 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like
51 | d2fk8a1 |
| not modelled | 99.3 | 22 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
52 | d1l1ea_ |
| not modelled | 99.3 | 21 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
53 | c3e05B_ |
| not modelled | 99.3 | 16 | PDB header:transferase Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating); PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
54 | d1kpia_ |
| not modelled | 99.3 | 15 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
55 | c2pwyB_ |
| not modelled | 99.3 | 23 | PDB header:transferase Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase; PDBTitle: crystal structure of a m1a58 trna methyltransferase
56 | d2b3ta1 |
| not modelled | 99.3 | 14 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK
57 | d1kpga_ |
| not modelled | 99.3 | 18 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
58 | c1wxwA_ |
| not modelled | 99.2 | 19 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ttha1280; PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8
59 | c3ujcA_ |
| not modelled | 99.2 | 14 | PDB header:transferase Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase; PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine
60 | d1tpya_ |
| not modelled | 99.2 | 20 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
61 | c3bgvC_ |
| not modelled | 99.2 | 18 | PDB header:transferase Chain: C: PDB Molecule:mrna cap guanine-n7 methyltransferase; PDBTitle: crystal structure of mrna cap guanine-n7 methyltransferase2 in complex with sah
62 | c3c0kB_ |
| not modelled | 99.2 | 16 | PDB header:transferase Chain: B: PDB Molecule:upf0064 protein yccw; PDBTitle: crystal structure of a ribosomal rna methyltranferase
63 | c3lpmA_ |
| not modelled | 99.2 | 16 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of putative methyltransferase small domain protein2 from listeria monocytogenes
64 | d1l3ia_ |
| not modelled | 99.2 | 21 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Precorrin-6Y methyltransferase (CbiT)
65 | c3ofkA_ |
| not modelled | 99.2 | 14 | PDB header:transferase Chain: A: PDB Molecule:nodulation protein s; PDBTitle: crystal structure of n-methyltransferase nods from bradyrhizobium2 japonicum wm9 in complex with s-adenosyl-l-homocysteine (sah)
66 | c3ku1E_ |
| not modelled | 99.2 | 15 | PDB header:transferase Chain: E: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
67 | d1i1na_ |
| not modelled | 99.2 | 23 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Protein-L-isoaspartyl O-methyltransferase
68 | d2b25a1 |
| not modelled | 99.2 | 24 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:tRNA(1-methyladenosine) methyltransferase-like
69 | c3grzA_ |
| not modelled | 99.2 | 15 | PDB header:transferase Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase; PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
70 | c1wg8B_ |
| not modelled | 99.2 | 30 | PDB header:transferase Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8.
71 | d1dusa_ |
| not modelled | 99.2 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical protein MJ0882
72 | c3lecA_ |
| not modelled | 99.1 | 15 | PDB header:structure genomics, unknown function Chain: A: PDB Molecule:nadb-rossmann superfamily protein; PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
73 | d1dl5a1 |
| not modelled | 99.1 | 23 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Protein-L-isoaspartyl O-methyltransferase
74 | d2nxca1 |
| not modelled | 99.1 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Ribosomal protein L11 methyltransferase PrmA
75 | d1jqea_ |
| not modelled | 99.1 | 18 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Histamine methyltransferase
76 | c3e23A_ |
| not modelled | 99.1 | 14 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein rpa2492; PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299
77 | d1xcla_ |
| not modelled | 99.1 | 11 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Guanidinoacetate methyltransferase
78 | c3a26A_ |
| not modelled | 99.1 | 19 | PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein ph0793; PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado
79 | c3ggdA_ |
| not modelled | 99.1 | 12 | PDB header:transferase Chain: A: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of sam-dependent methyltransferase (yp_325210.1)2 from anabaena variabilis atcc 29413 at 2.11 a resolution
80 | d1ve3a1 |
| not modelled | 99.1 | 25 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:CAC2371-like
81 | c1m6yA_ |
| not modelled | 99.1 | 24 | PDB header:transferase Chain: A: PDB Molecule:s-adenosyl-methyltransferase mraw; PDBTitle: crystal structure analysis of tm0872, a putative sam-2 dependent methyltransferase, complexed with sah
82 | c3hm2G_ |
| not modelled | 99.1 | 13 | PDB header:transferase Chain: G: PDB Molecule:precorrin-6y c5,15-methyltransferase; PDBTitle: crystal structure of putative precorrin-6y c5,15-2 methyltransferase targeted domain from corynebacterium3 diphtheriae
83 | d2o57a1 |
| not modelled | 99.1 | 20 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Mycolic acid cyclopropane synthase
84 | d2igta1 |
| not modelled | 99.1 | 14 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:hypothetical RNA methyltransferase
85 | c3e7pA_ |
| not modelled | 99.1 | 24 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of of putative methyltransferase from bacteroides2 vulgatus atcc 8482
86 | d1nkva_ |
| not modelled | 99.1 | 24 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Hypothetical Protein YjhP
87 | c3evzA_ |
| not modelled | 99.1 | 12 | PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus
88 | d1nv8a_ |
| not modelled | 99.1 | 13 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:N5-glutamine methyltransferase, HemK
89 | c3gnlB_ |
| not modelled | 99.1 | 14 | PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472; PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
90 | d2gh1a1 |
| not modelled | 99.1 | 15 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:BC2162-like
91 | c3dliB_ |
| not modelled | 99.1 | 15 | PDB header:transferase Chain: B: PDB Molecule:methyltransferase; PDBTitle: crystal structure of a sam dependent methyltransferase from2 archaeoglobus fulgidus
92 | c3ccfB_ |
| not modelled | 99.1 | 17 | PDB header:transferase Chain: B: PDB Molecule:cyclopropane-fatty-acyl-phospholipid synthase; PDBTitle: crystal structure of putative methyltransferase (yp_321342.1) from2 anabaena variabilis atcc 29413 at 1.90 a resolution
93 | d2frna1 |
| not modelled | 99.1 | 17 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Met-10+ protein-like
94 | d2fcaa1 |
| not modelled | 99.1 | 15 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:TrmB-like
95 | c1z3cA_ |
| not modelled | 99.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:mrna capping enzyme; PDBTitle: encephalitozooan cuniculi mrna cap (guanine-n7)2 methyltransferasein complexed with azoadomet
96 | d1ri5a_ |
| not modelled | 99.0 | 23 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:mRNA cap (Guanine N-7) methyltransferase
97 | c3ocjA_ |
| not modelled | 99.0 | 12 | PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative exported protein; PDBTitle: the crystal structure of a possilbe exported protein from bordetella2 parapertussis
98 | c3dmgA_ |
| not modelled | 99.0 | 17 | PDB header:transferase Chain: A: PDB Molecule:probable ribosomal rna small subunit methyltransferase; PDBTitle: t. thermophilus 16s rrna n2 g1207 methyltransferase (rsmc) in complex2 with adohcy
99 | c3f4kA_ |
| not modelled | 99.0 | 20 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of a probable methyltransferase from2 bacteroides thetaiotaomicron. northeast structural3 genomics target btr309.
100 | c1dl5A_ |
| not modelled | 99.0 | 23 | PDB header:transferase Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase; PDBTitle: protein-l-isoaspartate o-methyltransferase
101 | d1zx0a1 |
| not modelled | 99.0 | 11 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Guanidinoacetate methyltransferase
102 | c3njrB_ |
| not modelled | 99.0 | 16 | PDB header:transferase Chain: B: PDB Molecule:precorrin-6y methylase; PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus
103 | d2ex4a1 |
| not modelled | 99.0 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:AD-003 protein-like
104 | c2yxeB_ |
| not modelled | 99.0 | 22 | PDB header:transferase Chain: B: PDB Molecule:protein-l-isoaspartate o-methyltransferase; PDBTitle: crystal structure of l-isoaspartyl protein carboxyl methyltranferase
105 | c3dxyA_ |
| not modelled | 99.0 | 9 | PDB header:transferase Chain: A: PDB Molecule:trna (guanine-n(7)-)-methyltransferase; PDBTitle: crystal structure of ectrmb in complex with sam
106 | c3h2bB_ |
| not modelled | 99.0 | 20 | PDB header:transferase Chain: B: PDB Molecule:sam-dependent methyltransferase; PDBTitle: crystal structure of the sam-dependent methyltransferase2 cg3271 from corynebacterium glutamicum in complex with s-3 adenosyl-l-homocysteine and pyrophosphate. northeast4 structural genomics consortium target cgr113a
107 | d1r18a_ |
| not modelled | 99.0 | 25 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Protein-L-isoaspartyl O-methyltransferase
108 | c2pbfA_ |
| not modelled | 99.0 | 14 | PDB header:transferase Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase beta-aspartate PDBTitle: crystal structure of a putative protein-l-isoaspartate o-2 methyltransferase beta-aspartate methyltransferase (pcmt) from3 plasmodium falciparum in complex with s-adenosyl-l-homocysteine
109 | c3a27A_ |
| not modelled | 99.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:uncharacterized protein mj1557; PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet
110 | d1p1ca_ |
| not modelled | 99.0 | 11 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Guanidinoacetate methyltransferase
111 | d1xxla_ |
| not modelled | 99.0 | 13 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:UbiE/COQ5-like
112 | c2yx1A_ |
| not modelled | 99.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein mj0883; PDBTitle: crystal structure of m.jannaschii trna m1g37 methyltransferase
113 | c2yxdA_ |
| not modelled | 99.0 | 16 | PDB header:transferase Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit)
114 | c3duwB_ |
| not modelled | 99.0 | 14 | PDB header:transferase Chain: B: PDB Molecule:o-methyltransferase, putative; PDBTitle: crystal structural analysis of the o-methyltransferase from2 bacillus cereus in complex sah
115 | c2yr0A_ |
| not modelled | 99.0 | 22 | PDB header:transferase Chain: A: PDB Molecule:hypothetical protein ttha0223; PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8
116 | c3cc8A_ |
| not modelled | 99.0 | 13 | PDB header:transferase Chain: A: PDB Molecule:putative methyltransferase; PDBTitle: crystal structure of a putative methyltransferase (bce_1332) from2 bacillus cereus atcc 10987 at 1.64 a resolution
117 | d1r74a_ |
| not modelled | 99.0 | 16 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:Glycine N-methyltransferase
118 | c1vl5B_ |
| not modelled | 99.0 | 19 | PDB header:transferase Chain: B: PDB Molecule:unknown conserved protein bh2331; PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution
119 | d1y8ca_ |
| not modelled | 99.0 | 15 | Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:CAC2371-like
120 | c2pjdA_ |
| not modelled | 99.0 | 14 | PDB header:transferase Chain: A: PDB Molecule:ribosomal rna small subunit methyltransferase c; PDBTitle: crystal structure of 16s rrna methyltransferase rsmc

Binding site prediction |

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0