Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	K	N	I	Q	A	I	R	G	M	N	D	Y	L	P	G	E	T	A	I	W	Q	R	I	E	G	T	L	K	N	V	L	G	S	Y	G	Y	S	E	I	R	L	P	I	V	E	Q	T	P	L	F	K	R	A	I	G	E	V	T
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																													?	?	?	?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		D	V	V	E	K	E	M	Y	T	F	E	D	R	N	G	D	S	L	T	L	R	P	E	G	T	A	G	C	V	R	A	G	I	E	H	G	L	L	Y	N	Q	E	Q	R	L	W	Y	I	G	P	M	F	R	H	E	R	P	Q	K	G
Secondary structure
SS confidence
Disorder		?																																				?	?																		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		R	Y	R	Q	F	H	Q	L	G	C	E	V	F	G	L	Q	G	P	D	I	D	A	E	L	I	M	L	T	A	R	W	W	R	A	L	G	I	S	E	H	V	T	L	E	L	N	S	I	G	S	L	E	A	R	A	N	Y	R	D	A
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	V	A	F	L	E	Q	H	K	E	K	L	D	E	D	C	K	R	R	M	Y	T	N	P	L	R	V	L	D	S	K	N	P	E	V	Q	A	L	L	N	D	A	P	A	L	G	D	Y	L	D	E	E	S	R	E	H	F	A	G	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		C	K	L	L	E	S	A	G	I	A	Y	T	V	N	Q	R	L	V	R	G	L	D	Y	Y	N	R	T	V	F	E	W	V	T	N	S	L	G	S	Q	G	T	V	C	A	G	G	R	Y	D	G	L	V	E	Q	L	G	G	R	A	T
Secondary structure
SS confidence
Disorder																																			?					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		P	A	V	G	F	A	M	G	L	E	R	L	V	L	L	V	Q	A	V	N	P	E	F	K	A	D	P	V	V	D	I	Y	L	V	A	S	G	A	D	T	Q	S	A	A	M	A	L	A	E	R	L	R	D	E	L	P	G	V	K	L
Secondary structure
SS confidence
Disorder																			?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		M	T	N	H	G	G	G	N	F	K	K	Q	F	A	R	A	D	K	W	G	A	R	V	A	V	V	L	G	E	S	E	V	A	N	G	T	A	V	V	K	D	L	R	S	G	E	Q	T	A	V	A	Q	D	S	V	A	A	H	L	R
Secondary structure
SS confidence
Disorder						?		?	?																											?
Disorder confidence
		.	.	.	.
Sequence		T	L	L	G
Secondary structure
SS confidence
Disorder				?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ady chain A Region: 6 - 424 Aligned: 415 Modelled: 419 Confidence: 100.0% Identity: 42% PDB header:trna synthetase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate Phyre2 PDB 2el9 chain B Region: 4 - 424 Aligned: 376 Modelled: 376 Confidence: 100.0% Identity: 100% PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue Phyre2 PDB 1wu7 chain A Region: 1 - 423 Aligned: 413 Modelled: 423 Confidence: 100.0% Identity: 27% PDB header:ligase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum Phyre2 PDB 3net chain B Region: 4 - 423 Aligned: 405 Modelled: 420 Confidence: 100.0% Identity: 22% PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120 Phyre2 PDB 3hri chain F Region: 1 - 413 Aligned: 365 Modelled: 379 Confidence: 100.0% Identity: 25% PDB header:ligase Chain: F: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei Phyre2 PDB 1qe0 chain B Region: 5 - 420 Aligned: 336 Modelled: 357 Confidence: 100.0% Identity: 41% PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase Phyre2 PDB 2j3m chain A Region: 6 - 423 Aligned: 411 Modelled: 418 Confidence: 100.0% Identity: 19% PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol Phyre2 PDB 3od1 chain A Region: 2 - 385 Aligned: 361 Modelled: 380 Confidence: 100.0% Identity: 22% PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c Phyre2 PDB 2i4l chain C Region: 6 - 419 Aligned: 388 Modelled: 396 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: C: PDB Molecule:proline-trna ligase; PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase Phyre2 PDB 1fyf chain B Region: 6 - 423 Aligned: 361 Modelled: 372 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: B: PDB Molecule:threonyl-trna synthetase; PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog Phyre2 PDB 1qf6 chain A Region: 9 - 423 Aligned: 339 Modelled: 344 Confidence: 100.0% Identity: 19% PDB header:ligase/rna Chain: A: PDB Molecule:threonyl-trna synthetase; PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna Phyre2 PDB 1nyq chain A Region: 9 - 423 Aligned: 367 Modelled: 377 Confidence: 100.0% Identity: 18% PDB header:ligase Chain: A: PDB Molecule:threonyl-trna synthetase 1; PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate Phyre2 PDB 1ggm chain B Region: 8 - 423 Aligned: 367 Modelled: 376 Confidence: 100.0% Identity: 20% PDB header:ligase Chain: B: PDB Molecule:protein (glycyl-trna synthetase); PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate Phyre2 PDB 1ati chain A Region: 8 - 423 Aligned: 367 Modelled: 382 Confidence: 100.0% Identity: 20% PDB header:protein biosynthesis Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus Phyre2 PDB 3a32 chain A Region: 8 - 423 Aligned: 379 Modelled: 384 Confidence: 100.0% Identity: 17% PDB header:ligase Chain: A: PDB Molecule:probable threonyl-trna synthetase 1; PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix Phyre2 PDB 1nj8 chain C Region: 1 - 423 Aligned: 340 Modelled: 344 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: C: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii Phyre2 PDB 1kmm chain A domain 2 Region: 4 - 325 Aligned: 287 Modelled: 287 Confidence: 100.0% Identity: 100% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1z7m chain A domain 1 Region: 6 - 321 Aligned: 303 Modelled: 316 Confidence: 100.0% Identity: 20% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1wu7 chain A domain 2 Region: 1 - 324 Aligned: 317 Modelled: 324 Confidence: 100.0% Identity: 28% Fold: Class II aaRS and biotin synthetases Superfamily: Class II aaRS and biotin synthetases Family: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain Phyre2 PDB 1nj2 chain A Region: 1 - 423 Aligned: 320 Modelled: 331 Confidence: 100.0% Identity: 15% PDB header:ligase Chain: A: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus Phyre2 1 c1adyA_ 2 c2el9B_ 3 c1wu7A_ 4 c3netB_ 5 c3hriF_ 6 c1qe0B_ 7 c2j3mA_ 8 c3od1A_ 9 c2i4lC_ 10 c1fyfB_ 11 c1qf6A_ 12 c1nyqA_ 13 c1ggmB_ 14 c1atiA_ 15 c3a32A_ 16 c1nj8C_ 17 d1kmma2 18 d1z7ma1 19 d1wu7a2 20 c1nj2A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c1adyA_ 100.0 42 PDB header:trna synthetase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase in complex with histidyl-adenylate 2 c2el9B_ 100.0 100 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of e.coli histidyl-trna synthetase2 complexed with a histidyl-adenylate analogue 3 c1wu7A_ 100.0 27 PDB header:ligase Chain: A: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from2 thermoplasma acidophilum 4 c3netB_ 100.0 22 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of histidyl-trna synthetase from nostoc sp. pcc 7120 5 c3hriF_ 100.0 25 PDB header:ligase Chain: F: PDB Molecule:histidyl-trna synthetase; PDBTitle: histidyl-trna synthetase (apo) from trypanosoma brucei 6 c1qe0B_ 100.0 41 PDB header:ligase Chain: B: PDB Molecule:histidyl-trna synthetase; PDBTitle: crystal structure of apo s. aureus histidyl-trna synthetase 7 c2j3mA_ 100.0 19 PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol 8 c3od1A_ 100.0 22 PDB header:transferase Chain: A: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: the crystal structure of an atp phosphoribosyltransferase regulatory2 subunit/histidyl-trna synthetase from bacillus halodurans c 9 c2i4lC_ 100.0 17 PDB header:ligase Chain: C: PDB Molecule:proline-trna ligase; PDBTitle: rhodopseudomonas palustris prolyl-trna synthetase 10 c1fyfB_ 100.0 17 PDB header:ligase Chain: B: PDB Molecule:threonyl-trna synthetase; PDBTitle: crystal structure of a truncated form of threonyl-trna2 synthetase complexed with a seryl adenylate analog 11 c1qf6A_ 100.0 19 PDB header:ligase/rna Chain: A: PDB Molecule:threonyl-trna synthetase; PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna 12 c1nyqA_ 100.0 18 PDB header:ligase Chain: A: PDB Molecule:threonyl-trna synthetase 1; PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate 13 c1ggmB_ 100.0 20 PDB header:ligase Chain: B: PDB Molecule:protein (glycyl-trna synthetase); PDBTitle: glycyl-trna synthetase from thermus thermophilus complexed with2 glycyl-adenylate 14 c1atiA_ 100.0 20 PDB header:protein biosynthesis Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: crystal structure of glycyl-trna synthetase from thermus thermophilus 15 c3a32A_ 100.0 17 PDB header:ligase Chain: A: PDB Molecule:probable threonyl-trna synthetase 1; PDBTitle: crystal structure of putative threonyl-trna synthetase2 thrrs-1 from aeropyrum pernix 16 c1nj8C_ 100.0 15 PDB header:ligase Chain: C: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from2 methanocaldococcus janaschii 17 d1kmma2 100.0 100 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 18 d1z7ma1 100.0 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 19 d1wu7a2 100.0 28 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 20 c1nj2A_ 100.0 15 PDB header:ligase Chain: A: PDB Molecule:proline-trna synthetase; PDBTitle: crystal structure of prolyl-trna synthetase from methanothermobacter2 thermautotrophicus 21 c2pmfA_ not modelled 100.0 18 PDB header:ligase Chain: A: PDB Molecule:glycyl-trna synthetase; PDBTitle: the crystal structure of a human glycyl-trna synthetase mutant 22 c3ialB_ not modelled 100.0 14 PDB header:ligase Chain: B: PDB Molecule:prolyl-trna synthetase; PDBTitle: giardia lamblia prolyl-trna synthetase in complex with prolyl-2 adenylate 23 c1h4tD_ not modelled 100.0 18 PDB header:aminoacyl-trna synthetase Chain: D: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from thermus thermophilus complexed2 with l-proline 24 c1z7nB_ not modelled 100.0 22 PDB header:transferase Chain: B: PDB Molecule:atp phosphoribosyltransferase regulatory subunit; PDBTitle: atp phosphoribosyl transferase (hiszg atp-prtase) from2 lactococcus lactis with bound prpp substrate 25 d1h4vb2 not modelled 100.0 46 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 26 c3racA_ not modelled 100.0 24 PDB header:ligase Chain: A: PDB Molecule:histidine-trna ligase; PDBTitle: crystal strucutre of histidine--trna ligase subunit from2 alicyclobacillus acidocaldarius subsp. acidocaldarius dsm 446. 27 d1qe0a2 not modelled 100.0 44 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 28 c1g5hA_ not modelled 100.0 14 PDB header:dna binding protein Chain: A: PDB Molecule:mitochondrial dna polymerase accessory subunit; PDBTitle: crystal structure of the accessory subunit of murine mitochondrial2 polymerase gamma 29 c3ikmC_ not modelled 100.0 11 PDB header:transferase Chain: C: PDB Molecule:dna polymerase subunit gamma-2; PDBTitle: crystal structure of human mitochondrial dna polymerase2 holoenzyme 30 d1usya_ not modelled 100.0 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 31 d1nyra4 not modelled 100.0 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 32 d1e1oa2 not modelled 100.0 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 33 d1qf6a4 not modelled 100.0 21 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 34 d1bbua2 not modelled 100.0 12 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 35 d1nj8a3 not modelled 100.0 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 36 c3g1zB_ not modelled 99.9 15 PDB header:ligase Chain: B: PDB Molecule:putative lysyl-trna synthetase; PDBTitle: structure of idp01693/yjea, a potential t-rna synthetase from2 salmonella typhimurium 37 d1nj1a3 not modelled 99.9 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 38 d1b76a2 not modelled 99.9 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 39 d1atia2 not modelled 99.9 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 40 d1hc7a2 not modelled 99.9 19 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 41 c3mf2B_ not modelled 99.9 16 PDB header:ligase Chain: B: PDB Molecule:bll0957 protein; PDBTitle: crystal structure of class ii aars homologue (bll0957) complexed with2 amp 42 d1seta2 not modelled 99.9 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 43 c2cj9A_ not modelled 99.9 16 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of methanosarcina barkeri seryl-trna2 synthetase complexed with an analog of seryladenylate 44 c3lssA_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: trypanosoma brucei seryl-trna synthetase in complex with atp 45 c3qo8A_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of seryl-trna synthetase from candida albicans 46 c1wleB_ not modelled 99.9 14 PDB header:ligase Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of mammalian mitochondrial seryl-trna2 synthetase complexed with seryl-adenylate 47 c1sryB_ not modelled 99.9 14 PDB header:ligase(synthetase) Chain: B: PDB Molecule:seryl-trna synthetase; PDBTitle: refined crystal structure of the seryl-trna synthetase from2 thermus thermophilus at 2.5 angstroms resolution 48 d1eova2 not modelled 99.9 15 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 49 c2dq0A_ not modelled 99.9 15 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of seryl-trna synthetase from pyrococcus2 horikoshii complexed with a seryl-adenylate analog 50 c2dq3A_ not modelled 99.8 17 PDB header:ligase Chain: A: PDB Molecule:seryl-trna synthetase; PDBTitle: crystal structure of aq_298 51 d1qf6a1 not modelled 99.8 13 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 52 d1b8aa2 not modelled 99.8 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 53 d1nj1a1 not modelled 99.8 16 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 54 d1nj8a1 not modelled 99.8 12 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 55 d1nyra1 not modelled 99.8 17 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 56 d1kmma1 not modelled 99.8 100 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 57 c2znjB_ not modelled 99.8 18 PDB header:ligase Chain: B: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of pyrrolysyl-trna synthetase from2 desulfitobacterium hafniense 58 c3errB_ not modelled 99.8 14 PDB header:ligase Chain: B: PDB Molecule:fusion protein of microtubule binding domain from PDBTitle: microtubule binding domain from mouse cytoplasmic dynein as2 a fusion with seryl-trna synthetase 59 d1l0wa3 not modelled 99.8 16 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 60 d1hc7a1 not modelled 99.8 17 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 61 d1g5ha1 not modelled 99.8 11 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 62 d1c0aa3 not modelled 99.8 14 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 63 d1atia1 not modelled 99.8 24 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 64 d1h4vb1 not modelled 99.8 32 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 65 c2zimA_ not modelled 99.7 18 PDB header:ligase Chain: A: PDB Molecule:pyrrolysyl-trna synthetase; PDBTitle: pyrrolysyl-trna synthetase bound to adenylated pyrrolysine and2 pyrophosphate 66 d2g4ca1 not modelled 99.7 11 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 67 d1wu7a1 not modelled 99.7 25 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 68 d1qe0a1 not modelled 99.7 26 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 69 d1g5ha2 not modelled 99.7 13 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 70 d2g4ca2 not modelled 99.7 10 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 71 d1nnha_ not modelled 99.7 24 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 72 c1b70A_ not modelled 99.6 21 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase; PDBTitle: phenylalanyl trna synthetase complexed with phenylalanine 73 d1jjca_ not modelled 99.6 20 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 74 c1e22A_ not modelled 99.4 15 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase (lysu) hexagonal form complexed with2 lysine and the non-hydrolysable atp analogue amp-pcp 75 c3e9hB_ not modelled 99.4 20 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: lysyl-trna synthetase from bacillus stearothermophilus2 complexed with l-lysylsulfamoyl adenosine 76 c3l4gI_ not modelled 99.4 18 PDB header:ligase Chain: I: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 77 c3bjuB_ not modelled 99.3 18 PDB header:ligase Chain: B: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of tetrameric form of human lysyl-trna2 synthetase 78 c1eqrC_ not modelled 99.2 17 PDB header:ligase Chain: C: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of free aspartyl-trna synthetase from2 escherichia coli 79 c1efwA_ not modelled 99.2 19 PDB header:ligase/rna Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from thermus2 thermophilus complexed to trnaasp from escherichia coli 80 c2xgtB_ not modelled 99.1 14 PDB header:ligase Chain: B: PDB Molecule:asparaginyl-trna synthetase, cytoplasmic; PDBTitle: asparaginyl-trna synthetase from brugia malayi complexed2 with the sulphamoyl analogue of asparaginyl-adenylate 81 c1x55A_ not modelled 99.1 18 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase; PDBTitle: crystal structure of asparaginyl-trna synthetase from pyrococcus2 horikoshii complexed with asparaginyl-adenylate analogue 82 c1asyA_ not modelled 99.1 18 PDB header:complex (aminoacyl-trna synthase/trna) Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: class ii aminoacyl transfer rna synthetases: crystal2 structure of yeast aspartyl-trna synthetase complexed with3 trna asp 83 c1wydB_ not modelled 99.1 16 PDB header:ligase Chain: B: PDB Molecule:hypothetical aspartyl-trna synthetase; PDBTitle: crystal structure of aspartyl-trna synthetase from sulfolobus tokodaii 84 c1b8aB_ not modelled 99.0 18 PDB header:ligase Chain: B: PDB Molecule:protein (aspartyl-trna synthetase); PDBTitle: aspartyl-trna synthetase 85 c2du4B_ not modelled 99.0 18 PDB header:ligase/rna Chain: B: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of archaeoglobus fulgidus o-phosphoseryl-2 trna synthetase complexed with trnacys 86 c2rhqA_ not modelled 98.9 13 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase alpha chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 87 c3m4qA_ not modelled 98.9 17 PDB header:ligase Chain: A: PDB Molecule:asparaginyl-trna synthetase, putative; PDBTitle: entamoeba histolytica asparaginyl-trna synthetase (asnrs) 88 c3pcoC_ not modelled 98.7 15 PDB header:ligase Chain: C: PDB Molecule:phenylalanyl-trna synthetase, alpha subunit; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 89 c2du7C_ not modelled 98.7 18 PDB header:ligase Chain: C: PDB Molecule:o-phosphoseryl-trna synthetase; PDBTitle: crystal structure of methanococcus jannacshii o-phosphoseryl-trna2 synthetase 90 c3ig2B_ not modelled 98.4 15 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of a putative phenylalanyl-trna synthetase2 (phers) beta chain domain from bacteroides fragilis to 2.1a 91 c3i7fA_ not modelled 98.3 19 PDB header:ligase Chain: A: PDB Molecule:aspartyl-trna synthetase; PDBTitle: aspartyl trna synthetase from entamoeba histolytica 92 c3icaB_ not modelled 98.2 13 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: the crystal structure of the beta subunit of a phenylalanyl-trna2 synthetase from porphyromonas gingivalis w83 93 c3l4gL_ not modelled 98.1 9 PDB header:ligase Chain: L: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of homo sapiens cytoplasmic phenylalanyl-trna2 synthetase 94 d1v95a_ not modelled 97.8 14 Fold:Anticodon-binding domain-like Superfamily:Class II aaRS ABD-related Family:Anticodon-binding domain of Class II aaRS 95 d1jjcb5 not modelled 97.7 17 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 96 c2rhsB_ not modelled 97.5 16 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies 97 d1n9wa2 not modelled 97.4 18 Fold:Class II aaRS and biotin synthetases Superfamily:Class II aaRS and biotin synthetases Family:Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain 98 c3pcoD_ not modelled 97.4 14 PDB header:ligase Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain; PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp 99 c1n9wA_ not modelled 97.4 18 PDB header:biosynthetic protein Chain: A: PDB Molecule:aspartyl-trna synthetase 2; PDBTitle: crystal structure of the non-discriminating and archaeal-2 type aspartyl-trna synthetase from thermus thermophilus 100 c2akwB_ not modelled 96.7 15 PDB header:ligase Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain; PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine 101 c3cmqA_ not modelled 96.5 15 PDB header:ligase Chain: A: PDB Molecule:phenylalanyl-trna synthetase, mitochondrial; PDBTitle: crystal structure of human mitochondrial phenylalanine trna2 synthetase 102 d2cx4a1 not modelled 50.6 18 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione peroxidase-like 103 c2jwlB_ not modelled 47.6 13 PDB header:membrane protein Chain: B: PDB Molecule:protein tolr; PDBTitle: solution structure of periplasmic domain of tolr from h.2 influenzae with saxs data 104 d2jgra1 not modelled 40.7 13 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 105 c3h16A_ not modelled 40.2 24 PDB header:signaling protein Chain: A: PDB Molecule:tir protein; PDBTitle: crystal structure of a bacteria tir domain, pdtir from2 paracoccus denitrificans 106 c3or5A_ not modelled 24.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:thiol:disulfide interchange protein, thioredoxin family PDBTitle: crystal structure of thiol:disulfide interchange protein, thioredoxin2 family protein from chlorobium tepidum tls 107 d2bona1 not modelled 24.9 13 Fold:NAD kinase/diacylglycerol kinase-like Superfamily:NAD kinase/diacylglycerol kinase-like Family:Diacylglycerol kinase-like 108 d1u9da_ not modelled 22.2 12 Fold:Tautomerase/MIF Superfamily:Tautomerase/MIF Family:VC0714-like 109 c2yzhD_ not modelled 21.2 18 PDB header:oxidoreductase Chain: D: PDB Molecule:probable thiol peroxidase; PDBTitle: crystal structure of peroxiredoxin-like protein from aquifex aeolicus

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0