Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	P	F	M	T	E	D	F	L	L	D	T	E	F	A	R	R	L	Y	H	D	Y	A	K	D	Q	P	I	F	D	Y	H	C	H	L	P	P	Q	Q	I	A	E	D	Y	R	F	K	N	L	Y	D	I	W	L	K	G	D	H	Y
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		K	W	R	A	M	R	T	N	G	V	A	E	R	L	C	T	G	D	A	S	D	R	E	K	F	D	A	W	A	A	T	V	P	H	T	I	G	N	P	L	Y	H	W	T	H	L	E	L	R	R	P	F	G	I	T	G	K	L	L	S
Secondary structure
SS confidence
Disorder																?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	S	T	A	D	E	I	W	N	E	C	N	E	L	L	A	Q	D	N	F	S	A	R	G	I	M	Q	Q	M	N	V	K	M	V	G	T	T	D	D	P	I	D	S	L	E	H	H	A	E	I	A	K	D	G	S	F	T	I	K	V
Secondary structure
SS confidence
Disorder																	?	?	?																																		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	P	S	W	R	P	D	K	A	F	N	I	E	Q	A	T	F	N	D	Y	M	A	K	L	G	E	V	S	D	T	D	I	R	R	F	A	D	L	Q	T	A	L	T	K	R	L	D	H	F	A	A	H	G	C	K	V	S	D	H	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	D	V	V	M	F	A	E	A	N	E	A	E	L	D	S	I	L	A	R	R	L	A	G	E	T	L	S	E	H	E	V	A	Q	F	K	T	A	V	L	V	F	L	G	A	E	Y	A	R	R	G	W	V	Q	Q	Y	H	I	G	A
Secondary structure
SS confidence
Disorder																								?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	R	N	N	N	L	R	Q	F	K	L	L	G	P	D	V	G	F	D	S	I	N	D	R	P	M	A	E	E	L	S	K	L	L	S	K	Q	N	E	E	N	L	L	P	K	T	I	L	Y	C	L	N	P	R	D	N	E	V	L	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		T	M	I	G	N	F	Q	G	E	G	M	P	G	K	M	Q	F	G	S	G	W	W	F	N	D	Q	K	D	G	M	E	R	Q	M	T	Q	L	A	Q	L	G	L	L	S	R	F	V	G	M	L	T	D	S	R	S	F	L	S	Y	T
Secondary structure
SS confidence
Disorder												?																													?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470
Sequence		R	H	E	Y	F	R	R	I	L	C	Q	M	I	G	R	W	V	E	A	G	E	A	P	A	D	I	N	L	L	G	E	M	V	K	N	I	C	F	N	N	A	R	D	Y	F	A	I	E	L	N
Secondary structure
SS confidence
Disorder																																															?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3iac chain A Region: 3 - 468 Aligned: 465 Modelled: 463 Confidence: 100.0% Identity: 66% PDB header:isomerase Chain: A: PDB Molecule:glucuronate isomerase; PDBTitle: 2.2 angstrom crystal structure of glucuronate isomerase from2 salmonella typhimurium. Phyre2 PDB 2q01 chain A Region: 4 - 470 Aligned: 455 Modelled: 461 Confidence: 100.0% Identity: 26% PDB header:isomerase Chain: A: PDB Molecule:uronate isomerase; PDBTitle: crystal structure of glucuronate isomerase from caulobacter crescentus Phyre2 PDB 1j5s chain A Region: 4 - 465 Aligned: 446 Modelled: 456 Confidence: 100.0% Identity: 37% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Uronate isomerase-like Phyre2 PDB 2qee chain C domain 1 Region: 14 - 468 Aligned: 402 Modelled: 432 Confidence: 100.0% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: Uronate isomerase-like Phyre2 PDB 2qpx chain A Region: 22 - 468 Aligned: 353 Modelled: 386 Confidence: 99.9% Identity: 18% PDB header:hydrolase Chain: A: PDB Molecule:predicted metal-dependent hydrolase of the tim-barrel fold; PDBTitle: crystal structure of putative metal-dependent hydrolase (yp_805737.1)2 from lactobacillus casei atcc 334 at 1.40 a resolution Phyre2 PDB 1xwy chain A domain 1 Region: 194 - 467 Aligned: 222 Modelled: 229 Confidence: 96.3% Identity: 9% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3rcm chain A Region: 274 - 468 Aligned: 143 Modelled: 150 Confidence: 95.7% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida Phyre2 PDB 2dvt chain A domain 1 Region: 196 - 468 Aligned: 228 Modelled: 247 Confidence: 94.1% Identity: 12% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 2f6k chain A domain 1 Region: 280 - 466 Aligned: 156 Modelled: 177 Confidence: 92.1% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 1yix chain A domain 1 Region: 275 - 468 Aligned: 141 Modelled: 149 Confidence: 91.7% Identity: 11% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 3irs chain B Region: 280 - 467 Aligned: 141 Modelled: 166 Confidence: 90.6% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica Phyre2 PDB 3k2g chain A Region: 265 - 469 Aligned: 157 Modelled: 178 Confidence: 88.4% Identity: 24% PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides Phyre2 PDB 2ffi chain A domain 1 Region: 280 - 468 Aligned: 147 Modelled: 155 Confidence: 88.2% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 PDB 3nur chain A Region: 280 - 467 Aligned: 168 Modelled: 188 Confidence: 88.0% Identity: 10% PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus Phyre2 PDB 1j6o chain A Region: 274 - 466 Aligned: 139 Modelled: 148 Confidence: 87.1% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: TatD Mg-dependent DNase-like Phyre2 PDB 2wm1 chain A Region: 280 - 468 Aligned: 169 Modelled: 172 Confidence: 85.4% Identity: 11% PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis Phyre2 PDB 2rag chain B Region: 13 - 260 Aligned: 214 Modelled: 230 Confidence: 78.3% Identity: 14% PDB header:hydrolase Chain: B: PDB Molecule:dipeptidase; PDBTitle: crystal structure of aminohydrolase from caulobacter crescentus Phyre2 PDB 3pnz chain D Region: 274 - 468 Aligned: 159 Modelled: 165 Confidence: 76.2% Identity: 12% PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes Phyre2 PDB 3cjp chain A Region: 283 - 467 Aligned: 128 Modelled: 151 Confidence: 70.2% Identity: 13% PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum Phyre2 PDB 2hbv chain A domain 1 Region: 280 - 468 Aligned: 154 Modelled: 161 Confidence: 69.3% Identity: 14% Fold: TIM beta/alpha-barrel Superfamily: Metallo-dependent hydrolases Family: PP1699/LP2961-like Phyre2 1 c3iacA_ 2 c2q01A_ 3 d1j5sa_ 4 d2qeec1 5 c2qpxA_ 6 d1xwya1 7 c3rcmA_ 8 d2dvta1 9 d2f6ka1 10 d1yixa1 11 c3irsB_ 12 c3k2gA_ 13 d2ffia1 14 c3nurA_ 15 d1j6oa_ 16 c2wm1A_ 17 c2ragB_ 18 c3pnzD_ 19 c3cjpA_ 20 d2hbva1 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3iacA_ 100.0 66 PDB header:isomerase Chain: A: PDB Molecule:glucuronate isomerase; PDBTitle: 2.2 angstrom crystal structure of glucuronate isomerase from2 salmonella typhimurium. 2 c2q01A_ 100.0 26 PDB header:isomerase Chain: A: PDB Molecule:uronate isomerase; PDBTitle: crystal structure of glucuronate isomerase from caulobacter crescentus 3 d1j5sa_ 100.0 37 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Uronate isomerase-like 4 d2qeec1 100.0 16 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Uronate isomerase-like 5 c2qpxA_ 99.9 18 PDB header:hydrolase Chain: A: PDB Molecule:predicted metal-dependent hydrolase of the tim-barrel fold; PDBTitle: crystal structure of putative metal-dependent hydrolase (yp_805737.1)2 from lactobacillus casei atcc 334 at 1.40 a resolution 6 d1xwya1 96.3 9 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 7 c3rcmA_ 95.7 17 PDB header:hydrolase Chain: A: PDB Molecule:tatd family hydrolase; PDBTitle: crystal structure of efi target 500140:tatd family hydrolase from2 pseudomonas putida 8 d2dvta1 94.1 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 9 d2f6ka1 92.1 15 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 10 d1yixa1 91.7 11 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 11 c3irsB_ 90.6 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein bb4693; PDBTitle: crystal structure of uncharacterized tim-barrel protein bb4693 from2 bordetella bronchiseptica 12 c3k2gA_ 88.4 24 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 13 d2ffia1 88.2 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 14 c3nurA_ 88.0 10 PDB header:hydrolase Chain: A: PDB Molecule:amidohydrolase; PDBTitle: crystal structure of a putative amidohydrolase from staphylococcus2 aureus 15 d1j6oa_ 87.1 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 16 c2wm1A_ 85.4 11 PDB header:lyase Chain: A: PDB Molecule:2-amino-3-carboxymuconate-6-semialdehyde PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis 17 c2ragB_ 78.3 14 PDB header:hydrolase Chain: B: PDB Molecule:dipeptidase; PDBTitle: crystal structure of aminohydrolase from caulobacter crescentus 18 c3pnzD_ 76.2 12 PDB header:hydrolase Chain: D: PDB Molecule:phosphotriesterase family protein; PDBTitle: crystal structure of the lactonase lmo2620 from listeria monocytogenes 19 c3cjpA_ 70.2 13 PDB header:hydrolase Chain: A: PDB Molecule:predicted amidohydrolase, dihydroorotase family; PDBTitle: crystal structure of an uncharacterized amidohydrolase cac3332 from2 clostridium acetobutylicum 20 d2hbva1 69.3 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:PP1699/LP2961-like 21 c2xioA_ not modelled 67.8 11 PDB header:hydrolase Chain: A: PDB Molecule:putative deoxyribonuclease tatdn1; PDBTitle: structure of putative deoxyribonuclease tatdn1 isoform a 22 c2xi5D_ not modelled 67.3 50 PDB header:transferase Chain: D: PDB Molecule:rna polymerase l; PDBTitle: n-terminal endonuclease domain of la crosse virus l-protein 23 c2xi7B_ not modelled 67.2 50 PDB header:transferase Chain: B: PDB Molecule:rna polymerase l; PDBTitle: n-terminal endonuclease domain of la crosse virus l-protein 24 c3ipwA_ not modelled 62.5 21 PDB header:hydrolase Chain: A: PDB Molecule:hydrolase tatd family protein; PDBTitle: crystal structure of hydrolase tatd family protein from entamoeba2 histolytica 25 c1pscA_ not modelled 61.5 16 PDB header:hydrolase Chain: A: PDB Molecule:phosphotriesterase; PDBTitle: phosphotriesterase from pseudomonas diminuta 26 d1vmea1 not modelled 60.0 9 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 27 c2gzxB_ not modelled 59.6 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative tatd related dnase; PDBTitle: crystal structure of the tatd deoxyribonuclease mw0446 from2 staphylococcus aureus. northeast structural genomics consortium3 target zr237. 28 c3f4cA_ not modelled 59.3 12 PDB header:hydrolase Chain: A: PDB Molecule:organophosphorus hydrolase; PDBTitle: crystal structure of organophosphorus hydrolase from geobacillus2 stearothermophilus strain 10, with glycerol bound 29 c3guwB_ not modelled 58.9 14 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein af_1765; PDBTitle: crystal structure of the tatd-like protein (af1765) from2 archaeoglobus fulgidus, northeast structural genomics3 consortium target gr121 30 c3gg7A_ not modelled 56.2 17 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized metalloprotein; PDBTitle: crystal structure of an uncharacterized metalloprotein from2 deinococcus radiodurans 31 d1zzma1 not modelled 56.2 19 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:TatD Mg-dependent DNase-like 32 d1bf6a_ not modelled 55.3 17 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 33 d1e5da1 not modelled 50.0 15 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 34 c2qahA_ not modelled 49.9 13 PDB header:hydrolase Chain: A: PDB Molecule:2-pyrone-4,6-dicarboxylic acid hydrolase; PDBTitle: crystal structure of the 2-pyrone-4,6-dicarboxylic acid2 hydrolase from sphingomonas paucimobilis 35 c2fmoA_ not modelled 47.5 14 PDB header:oxidoreductase Chain: A: PDB Molecule:5,10-methylenetetrahydrofolate reductase; PDBTitle: ala177val mutant of e. coli methylenetetrahydrofolate2 reductase 36 d1xrta2 not modelled 44.4 7 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 37 d2amxa1 not modelled 44.0 30 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Adenosine/AMP deaminase 38 c3ou8B_ not modelled 38.6 29 PDB header:hydrolase Chain: B: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 39 d1yoba1 not modelled 38.0 18 Fold:Flavodoxin-like Superfamily:Flavoproteins Family:Flavodoxin-related 40 d1w5ra1 not modelled 35.7 23 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase 41 d1zbsa1 not modelled 33.9 11 Fold:Ribonuclease H-like motif Superfamily:Actin-like ATPase domain Family:BadF/BadG/BcrA/BcrD-like 42 d1bpoa1 not modelled 33.5 21 Fold:alpha-alpha superhelix Superfamily:ARM repeat Family:Clathrin heavy-chain linker domain 43 c3ou8A_ not modelled 33.1 29 PDB header:hydrolase Chain: A: PDB Molecule:adenosine deaminase; PDBTitle: the crystal structure of adenosine deaminase from pseudomonas2 aeruginosa 44 c1deqF_ not modelled 32.9 64 PDB header: PDB COMPND: 45 d2ffha2 not modelled 31.9 32 Fold:Signal peptide-binding domain Superfamily:Signal peptide-binding domain Family:Signal peptide-binding domain 46 c2w48D_ not modelled 31.4 16 PDB header:transcription Chain: D: PDB Molecule:sorbitol operon regulator; PDBTitle: crystal structure of the full-length sorbitol operon2 regulator sorc from klebsiella pneumoniae 47 c3dzdA_ not modelled 30.3 18 PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator (ntrc family); PDBTitle: crystal structure of sigma54 activator ntrc4 in the inactive2 state 48 d2cbia2 not modelled 29.7 22 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:alpha-D-glucuronidase/Hyaluronidase catalytic domain 49 c1zbsA_ not modelled 28.8 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein pg1100; PDBTitle: crystal structure of the putative n-acetylglucosamine kinase (pg1100)2 from porphyromonas gingivalis, northeast structural genomics target3 pgr18 50 c1ei3E_ not modelled 28.2 45 PDB header: PDB COMPND: 51 d1k78a1 not modelled 27.6 30 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Paired domain 52 c3ghgK_ not modelled 26.9 45 PDB header:blood clotting Chain: K: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of human fibrinogen 53 d2ajta2 not modelled 26.7 15 Fold:FucI/AraA N-terminal and middle domains Superfamily:FucI/AraA N-terminal and middle domains Family:AraA N-terminal and middle domain-like 54 c1deqO_ not modelled 26.3 42 PDB header: PDB COMPND: 55 c2y7eA_ not modelled 26.0 12 PDB header:lyase Chain: A: PDB Molecule:3-keto-5-aminohexanoate cleavage enzyme; PDBTitle: crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme2 (kce) from candidatus cloacamonas acidaminovorans (tetragonal form) 56 c2yz5B_ not modelled 25.6 25 PDB header:hydrolase Chain: B: PDB Molecule:histidinol phosphatase; PDBTitle: histidinol phosphate phosphatase complexed with phosphate 57 d1qb2a_ not modelled 25.4 24 Fold:Signal peptide-binding domain Superfamily:Signal peptide-binding domain Family:Signal peptide-binding domain 58 d1jjcb2 not modelled 24.8 26 Fold:Putative DNA-binding domain Superfamily:Putative DNA-binding domain Family:Domains B1 and B5 of PheRS-beta, PheT 59 d1khda1 not modelled 24.6 19 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 60 c1zxoB_ not modelled 24.1 14 PDB header:unknown function Chain: B: PDB Molecule:conserved hypothetical protein q8a1p1; PDBTitle: x-ray crystal structure of protein q8a1p1 from bacteroides2 thetaiotaomicron. northeast structural genomics consortium3 target btr25. 61 c1ei3C_ not modelled 23.5 64 PDB header: PDB COMPND: 62 d2tpta1 not modelled 22.8 22 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 63 c2wc1A_ not modelled 22.7 16 PDB header:electron transport Chain: A: PDB Molecule:flavodoxin; PDBTitle: three-dimensional structure of the nitrogen fixation2 flavodoxin (niff) from rhodobacter capsulatus at 2.2 a 64 d2fvka2 not modelled 22.4 13 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Hydantoinase (dihydropyrimidinase), catalytic domain 65 c3h87D_ not modelled 22.1 42 PDB header:toxin/antitoxin Chain: D: PDB Molecule:putative uncharacterized protein; PDBTitle: rv0301 rv0300 toxin antitoxin complex from mycobacterium tuberculosis 66 c1lwuH_ not modelled 22.1 36 PDB header:blood clotting Chain: H: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of fragment d from lamprey fibrinogen complexed with2 the peptide gly-his-arg-pro-amide 67 c2yguA_ not modelled 21.1 35 PDB header:allergen Chain: A: PDB Molecule:venom allergen 2; PDBTitle: crystal structure of fire ant venom allergen, sol i 2 68 d1w4ta1 not modelled 20.7 19 Fold:Cysteine proteinases Superfamily:Cysteine proteinases Family:Arylamine N-acetyltransferase 69 d1ra0a2 not modelled 20.5 22 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Cytosine deaminase catalytic domain 70 c3bvhC_ not modelled 19.9 64 PDB header:blood clotting Chain: C: PDB Molecule:fibrinogen gamma chain; PDBTitle: crystal structure of recombinant gammad364a fibrinogen fragment d with2 the peptide ligand gly-pro-arg-pro-amide 71 c1n73C_ not modelled 19.4 64 PDB header:blood clotting Chain: C: PDB Molecule:fibrin gamma chain; PDBTitle: fibrin d-dimer, lamprey complexed with the peptide ligand: gly-his-2 arg-pro-amide 72 c2hpcF_ not modelled 19.2 64 PDB header:blood clotting Chain: F: PDB Molecule:fibrinogen, gamma polypeptide; PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide. 73 c3bvhE_ not modelled 19.2 50 PDB header:blood clotting Chain: E: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of recombinant gammad364a fibrinogen fragment d with2 the peptide ligand gly-pro-arg-pro-amide 74 d1qzxa2 not modelled 19.0 24 Fold:Signal peptide-binding domain Superfamily:Signal peptide-binding domain Family:Signal peptide-binding domain 75 c2infB_ not modelled 18.9 11 PDB header:lyase Chain: B: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: crystal structure of uroporphyrinogen decarboxylase from2 bacillus subtilis 76 d1lwuc1 not modelled 18.9 64 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 77 c3kwkA_ not modelled 18.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative nadh dehydrogenase/nad(p)h nitroreductase; PDBTitle: crystal structure of putative nadh dehydrogenase/nad(p)h2 nitroreductase (np_809094.1) from bacteroides thetaiotaomicron vpi-3 5482 at 1.54 a resolution 78 d1o17a1 not modelled 18.4 18 Fold:Methionine synthase domain-like Superfamily:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Family:Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain 79 c2hpcH_ not modelled 18.3 42 PDB header:blood clotting Chain: H: PDB Molecule:fibrinogen beta chain; PDBTitle: crystal structure of fragment d from human fibrinogen complexed with2 gly-pro-arg-pro-amide. 80 c2j61B_ not modelled 18.1 27 PDB header:lectin Chain: B: PDB Molecule:ficolin-2; PDBTitle: l-ficolin complexed to n-acetylglucosamine (forme c) 81 d1m1jc1 not modelled 18.1 64 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 82 d1lwub1 not modelled 17.7 36 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 83 d6paxa1 not modelled 17.7 33 Fold:DNA/RNA-binding 3-helical bundle Superfamily:Homeodomain-like Family:Paired domain 84 c3m1eA_ not modelled 17.6 18 PDB header:transcription regulator Chain: A: PDB Molecule:hth-type transcriptional regulator benm; PDBTitle: crystal structure of benm_dbd 85 c2vc7A_ not modelled 16.4 12 PDB header:hydrolase Chain: A: PDB Molecule:aryldialkylphosphatase; PDBTitle: structural basis for natural lactonase and promiscuous2 phosphotriesterase activities 86 d1fida_ not modelled 16.3 64 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 87 d2paja2 not modelled 16.2 12 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:SAH/MTA deaminase-like 88 c2i7hE_ not modelled 15.9 8 PDB header:oxidoreductase Chain: E: PDB Molecule:nitroreductase-like family protein; PDBTitle: crystal structure of the nitroreductase-like family protein from2 bacillus cereus 89 d1re3b1 not modelled 15.8 42 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 90 d1i0da_ not modelled 15.8 14 Fold:TIM beta/alpha-barrel Superfamily:Metallo-dependent hydrolases Family:Phosphotriesterase-like 91 c2vfbA_ not modelled 15.6 15 PDB header:transferase Chain: A: PDB Molecule:arylamine n-acetyltransferase; PDBTitle: the structure of mycobacterium marinum arylamine n-2 acetyltransferase 92 d1jc9a_ not modelled 15.4 27 Fold:Fibrinogen C-terminal domain-like Superfamily:Fibrinogen C-terminal domain-like Family:Fibrinogen C-terminal domain-like 93 c1jc9A_ not modelled 15.4 27 PDB header:sugar binding protein Chain: A: PDB Molecule:techylectin-5a; PDBTitle: tachylectin 5a from tachypleus tridentatus (japanese horseshoe crab) 94 c3tgnA_ not modelled 15.0 8 PDB header:transcription Chain: A: PDB Molecule:adc operon repressor adcr; PDBTitle: crystal structure of the zinc-dependent marr family transcriptional2 regulator adcr in the zn(ii)-bound state 95 c3r6uA_ not modelled 15.0 13 PDB header:transport protein Chain: A: PDB Molecule:choline-binding protein; PDBTitle: crystal structure of choline binding protein opubc from bacillus2 subtilis 96 c2jubA_ not modelled 14.7 38 PDB header:endonuclease inhibitor Chain: A: PDB Molecule:internal protein i; PDBTitle: solution structure of ipi* 97 c3pjwA_ not modelled 14.7 8 PDB header:lyase Chain: A: PDB Molecule:cyclic dimeric gmp binding protein; PDBTitle: structure of pseudomonas fluorescence lapd ggdef-eal dual domain, i23 98 c1af7A_ not modelled 14.6 15 PDB header:methyltransferase Chain: A: PDB Molecule:chemotaxis receptor methyltransferase cher; PDBTitle: cher from salmonella typhimurium 99 d1rrma_ not modelled 14.5 13 Fold:Dehydroquinate synthase-like Superfamily:Dehydroquinate synthase-like Family:Iron-containing alcohol dehydrogenase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0