PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c2wm1A_

Fold library id	PDB Header	Molecule	Title
c2wm1A_	PDB header: lyase	Chain: A: PDB Molecule: 2-amino-3-carboxymuconate-6-semialdehyde	PDBTitle: the crystal structure of human alpha-amino-beta-2 carboxymuconate-epsilon-semialdehyde decarboxylase in3 complex with 1,3- dihydroxyacetonephosphate suggests a4 regulatory link between nad synthesis and glycolysis

Links to external resources
Added to library: Sun Aug 29 03:59:30 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence M K I D I H S H I L P K E W P D L K K R F G Y G G W V Q L Q H H S K G E A K L L K D G K V F R V V R E N C W D P E V R I R E M D Q K G V T V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
T T T T G G G T
T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Q A L S T V P V M F S Y W A K P E D T L N L C Q L L N N D L A S T V V S Y P R R F V G L G T L P M Q A P E L A V K E M E R C V K E L G F P G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G G
T T S
S T T T
T T S T S
S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence V Q I G T H V N E W D L N A Q E L F P V Y A A A E R L K C S L F V H P W D M Q M D G R M A K Y W L P W L V G M P A E T T I A I C S M I M G G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T T T
G G G T
S
S G G G S S T T T T T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence V F E K F P K L K V C F A H G G G A F P F T V G R I S H G F S M R P D L C A Q D N P M N P K K Y L G S F Y T D A L V H D P L S L K L L T D V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
S G G G T T
S S S
S
G G G G T T S S
S

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . .

Sequence I G K D K V I L G T D Y P F P L G E L E P G K L I E S M E E F D E E T K N K L K A G N A L A F L G L E R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
B T S T T S
S S T T T
T T S
T T

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	M	K	I	D	I	H	S	H	I	L	P	K	E	W	P	D	L	K	K	R	F	G	Y	G	G	W	V	Q	L	Q	H	H	S	K	G	E	A	K	L	L	K	D	G	K	V	F	R	V	V	R	E	N	C	W	D	P	E	V	R	I	R	E	M	D	Q	K	G	V	T	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)												S										S	S											T	T							T	T								G	G	G	T													T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Q	A	L	S	T	V	P	V	M	F	S	Y	W	A	K	P	E	D	T	L	N	L	C	Q	L	L	N	N	D	L	A	S	T	V	V	S	Y	P	R	R	F	V	G	L	G	T	L	P	M	Q	A	P	E	L	A	V	K	E	M	E	R	C	V	K	E	L	G	F	P	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)							G	G	G	G		T	T	S																							S	T	T	T									T	T	S														T	S			S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	V	Q	I	G	T	H	V	N	E	W	D	L	N	A	Q	E	L	F	P	V	Y	A	A	A	E	R	L	K	C	S	L	F	V	H	P	W	D	M	Q	M	D	G	R	M	A	K	Y	W	L	P	W	L	V	G	M	P	A	E	T	T	I	A	I	C	S	M	I	M	G	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)					S			T	T			T	T		G	G	G											T									S				S	G	G	G	S	S	T	T					T																T	T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	V	F	E	K	F	P	K	L	K	V	C	F	A	H	G	G	G	A	F	P	F	T	V	G	R	I	S	H	G	F	S	M	R	P	D	L	C	A	Q	D	N	P	M	N	P	K	K	Y	L	G	S	F	Y	T	D	A	L	V	H	D	P	L	S	L	K	L	L	T	D	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T						S	G	G	G	T	T																				S	S	S			S		G	G	G	G	T	T	S	S								S
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.
Sequence	I	G	K	D	K	V	I	L	G	T	D	Y	P	F	P	L	G	E	L	E	P	G	K	L	I	E	S	M	E	E	F	D	E	E	T	K	N	K	L	K	A	G	N	A	L	A	F	L	G	L	E	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S							B	T	S	T	T	S		S	S	T	T					T		T	T	S										T								T