Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0AG20
DateThu Jan 5 11:27:53 GMT 2012
Unique Job IDd7085604ab271c15

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1vj7B_
Top template information
PDB header:hydrolase, transferase
Chain: B: PDB Molecule:bifunctional rela/spot;
PDBTitle: crystal structure of the bifunctional catalytic fragment of relseq,2 the rela/spot homolog from streptococcus equisimilis.
Confidence and coverage
Confidence:100.0% Coverage: 40%
299 residues ( 40% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
530 residues ( 71%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGV
Secondary structure 
SS confidence 
Disorder  ?????????
?
????
Disorder confidence 
 
   .........70.........80.........90.........100.........110.........120
Sequence  EMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLK
Secondary structure 
SS confidence 
Disorder 
?????
Disorder confidence 
 
   .........130.........140.........150.........160.........170.........180
Sequence  ATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTN
Secondary structure 
SS confidence 
Disorder  ????????
?
Disorder confidence 
 
   .........190.........200.........210.........220.........230.........240
Sequence  IYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEM
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........250.........260.........270.........280.........290.........300
Sequence  KAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHY
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 
   .........310.........320.........330.........340.........350.........360
Sequence  RHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEG
Secondary structure 
SS confidence 
Disorder 
?
???
Disorder confidence 
 
   .........370.........380.........390.........400.........410.........420
Sequence  AAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPA
Secondary structure 
SS confidence 
Disorder  ???????
???????
Disorder confidence 
 
   .........430.........440.........450.........460.........470.........480
Sequence  GSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNL
Secondary structure 
SS confidence 
Disorder 
??
??????
Disorder confidence 
 
   .........490.........500.........510.........520.........530.........540
Sequence  GYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVD
Secondary structure 
SS confidence 
Disorder 
?
????
Disorder confidence 
 
   .........550.........560.........570.........580.........590.........600
Sequence  ELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVE
Secondary structure 
SS confidence 
Disorder 
??????????????????????????????????
Disorder confidence 
 
   .........610.........620.........630.........640.........650.........660
Sequence  GVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGES
Secondary structure 
SS confidence 
Disorder 
????
?
?
Disorder confidence 
 
   .........670.........680.........690.........700.........710.........720
Sequence  YSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQ
Secondary structure 
SS confidence 
Disorder  ??
?
?
?
Disorder confidence 
 
   .........730.........740....
Sequence  VLGRVLGKLNQVPDVIDARRLHGS
Secondary structure 
SS confidence 
Disorder 
???
?
????
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1vj7 chain B

3D model

Region: 15 - 355
Aligned: 299
Modelled: 315
Confidence: 100.0%
Identity: 39%
PDB header:hydrolase, transferase
Chain: B: PDB Molecule:bifunctional rela/spot;
PDBTitle: crystal structure of the bifunctional catalytic fragment of relseq,2 the rela/spot homolog from streptococcus equisimilis.

Phyre2

PDB 1vj7 chain A domain 1

3D model

Region: 14 - 207
Aligned: 168
Modelled: 174
Confidence: 100.0%
Identity: 30%
Fold: HD-domain/PDEase-like
Superfamily: HD-domain/PDEase-like
Family: HD domain

Phyre2

PDB 3nr1 chain A

3D model

Region: 31 - 214
Aligned: 169
Modelled: 184
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:hd domain-containing protein 3;
PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses

Phyre2

PDB 1vj7 chain A domain 2

3D model

Region: 207 - 360
Aligned: 151
Modelled: 154
Confidence: 100.0%
Identity: 49%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: RelA/SpoT domain

Phyre2

PDB 3nqw chain B

3D model

Region: 33 - 201
Aligned: 155
Modelled: 169
Confidence: 100.0%
Identity: 21%
PDB header:hydrolase
Chain: B: PDB Molecule:cg11900;
PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses

Phyre2

PDB 2be3 chain A domain 1

3D model

Region: 210 - 403
Aligned: 188
Modelled: 194
Confidence: 100.0%
Identity: 21%
Fold: Nucleotidyltransferase
Superfamily: Nucleotidyltransferase
Family: RelA/SpoT domain

Phyre2

PDB 3l9d chain A

3D model

Region: 211 - 401
Aligned: 178
Modelled: 191
Confidence: 99.9%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:putative gtp pyrophosphokinase;
PDBTitle: the crystal structure of smu.1046c from streptococcus mutans ua159

Phyre2

PDB 2kmm chain A

3D model

Region: 405 - 474
Aligned: 70
Modelled: 70
Confidence: 99.9%
Identity: 49%
PDB header:hydrolase
Chain: A: PDB Molecule:guanosine-3',5'-bis(diphosphate) 3'-
PDBTitle: solution nmr structure of the tgs domain of pg1808 from2 porphyromonas gingivalis. northeast structural genomics3 consortium target pgr122a (418-481)

Phyre2

PDB 3hvz chain B

3D model

Region: 404 - 467
Aligned: 64
Modelled: 64
Confidence: 99.9%
Identity: 59%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the tgs domain of the clolep_03100 protein from2 clostridium leptum, northeast structural genomics consortium target3 qlr13a

Phyre2

PDB 2eki chain A

3D model

Region: 406 - 470
Aligned: 65
Modelled: 65
Confidence: 99.8%
Identity: 32%
PDB header:signaling protein
Chain: A: PDB Molecule:developmentally-regulated gtp-binding protein 1;
PDBTitle: solution structures of the tgs domain of human2 developmentally-regulated gtp-binding protein 1

Phyre2

PDB 1tke chain A domain 1

3D model

Region: 406 - 466
Aligned: 61
Modelled: 61
Confidence: 99.7%
Identity: 23%
Fold: beta-Grasp (ubiquitin-like)
Superfamily: TGS-like
Family: TGS domain

Phyre2

PDB 1wxq chain A domain 2

3D model

Region: 414 - 465
Aligned: 52
Modelled: 52
Confidence: 99.7%
Identity: 35%
Fold: beta-Grasp (ubiquitin-like)
Superfamily: TGS-like
Family: G domain-linked domain

Phyre2

PDB 1nyr chain A domain 2

3D model

Region: 406 - 464
Aligned: 59
Modelled: 59
Confidence: 99.7%
Identity: 25%
Fold: beta-Grasp (ubiquitin-like)
Superfamily: TGS-like
Family: TGS domain

Phyre2

PDB 3ibw chain A

3D model

Region: 663 - 742
Aligned: 78
Modelled: 80
Confidence: 99.6%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:gtp pyrophosphokinase;
PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a

Phyre2

PDB 1wwt chain A

3D model

Region: 403 - 473
Aligned: 71
Modelled: 71
Confidence: 99.5%
Identity: 18%
PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase, cytoplasmic;
PDBTitle: solution structure of the tgs domain from human threonyl-2 trna synthetase

Phyre2

PDB 1u8s chain A domain 2

3D model

Region: 661 - 739
Aligned: 77
Modelled: 79
Confidence: 98.6%
Identity: 16%
Fold: Ferredoxin-like
Superfamily: ACT-like
Family: Glycine cleavage system transcriptional repressor

Phyre2

PDB 1tke chain A

3D model

Region: 406 - 468
Aligned: 63
Modelled: 63
Confidence: 98.6%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of the editing domain of threonyl-trna2 synthetase complexed with serine

Phyre2

PDB 2dwq chain B

3D model

Region: 406 - 466
Aligned: 60
Modelled: 60
Confidence: 98.4%
Identity: 33%
PDB header:hydrolase
Chain: B: PDB Molecule:gtp-binding protein;
PDBTitle: thermus thermophilus ychf gtp-binding protein

Phyre2

PDB 1sc6 chain A domain 3

3D model

Region: 668 - 741
Aligned: 71
Modelled: 74
Confidence: 98.3%
Identity: 23%
Fold: Ferredoxin-like
Superfamily: ACT-like
Family: Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain

Phyre2

PDB 2ohf chain A

3D model

Region: 377 - 466
Aligned: 90
Modelled: 90
Confidence: 98.2%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:gtp-binding protein 9;
PDBTitle: crystal structure of human ola1 in complex with amppcp

Phyre2

PDB 2nyi chain B

3D model

Region: 642 - 732
Aligned: 90
Modelled: 89
Confidence: 97.5%
Identity: 16%
PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:unknown protein;
PDBTitle: crystal structure of an unknown protein from galdieria2 sulphuraria

Phyre2

PDB 2kgr chain A

3D model

Region: 471 - 546
Aligned: 68
Modelled: 68
Confidence: 62.1%
Identity: 13%
PDB header:protein binding
Chain: A: PDB Molecule:intersectin-1;
PDBTitle: solution structure of protein itsn1 from homo sapiens.2 northeast structural genomics consortium target hr5524a

Phyre2
1
c1vj7B_
2
d1vj7a1
3
c3nr1A_
4
d1vj7a2
5
c3nqwB_
6
d2be3a1
7
c3l9dA_
8
c2kmmA_
9
c3hvzB_
10
c2ekiA_
11
d1tkea1
12
d1wxqa2
13
d1nyra2
14
c3ibwA_
15
c1wwtA_
16
d1u8sa2
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c1tkeA_
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c2dwqB_
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d1sc6a3
20
c2ohfA_
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c2nyiB_
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c2kgrA_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1vj7B_
100.0 39 PDB header:hydrolase, transferase
Chain: B: PDB Molecule:bifunctional rela/spot;
PDBTitle: crystal structure of the bifunctional catalytic fragment of relseq,2 the rela/spot homolog from streptococcus equisimilis.
2d1vj7a1
100.0 30 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
3c3nr1A_
100.0 21 PDB header:hydrolase
Chain: A: PDB Molecule:hd domain-containing protein 3;
PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses
4d1vj7a2
100.0 49 Fold:Nucleotidyltransferase
Superfamily:Nucleotidyltransferase
Family:RelA/SpoT domain
5c3nqwB_
100.0 21 PDB header:hydrolase
Chain: B: PDB Molecule:cg11900;
PDBTitle: a metazoan ortholog of spot hydrolyzes ppgpp and plays a role in2 starvation responses
6d2be3a1
100.0 21 Fold:Nucleotidyltransferase
Superfamily:Nucleotidyltransferase
Family:RelA/SpoT domain
7c3l9dA_
99.9 24 PDB header:transferase
Chain: A: PDB Molecule:putative gtp pyrophosphokinase;
PDBTitle: the crystal structure of smu.1046c from streptococcus mutans ua159
8c2kmmA_
99.9 49 PDB header:hydrolase
Chain: A: PDB Molecule:guanosine-3',5'-bis(diphosphate) 3'-
PDBTitle: solution nmr structure of the tgs domain of pg1808 from2 porphyromonas gingivalis. northeast structural genomics3 consortium target pgr122a (418-481)
9c3hvzB_
99.9 59 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: crystal structure of the tgs domain of the clolep_03100 protein from2 clostridium leptum, northeast structural genomics consortium target3 qlr13a
10c2ekiA_
99.8 32 PDB header:signaling protein
Chain: A: PDB Molecule:developmentally-regulated gtp-binding protein 1;
PDBTitle: solution structures of the tgs domain of human2 developmentally-regulated gtp-binding protein 1
11d1tkea1
99.7 23 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:TGS domain
12d1wxqa2
99.7 35 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:G domain-linked domain
13d1nyra2
99.7 25 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:TGS domain
14c3ibwA_
99.6 23 PDB header:transferase
Chain: A: PDB Molecule:gtp pyrophosphokinase;
PDBTitle: crystal structure of the act domain from gtp2 pyrophosphokinase of chlorobium tepidum. northeast3 structural genomics consortium target ctr148a
15c1wwtA_
99.5 18 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase, cytoplasmic;
PDBTitle: solution structure of the tgs domain from human threonyl-2 trna synthetase
16d1u8sa2
98.6 16 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Glycine cleavage system transcriptional repressor
17c1tkeA_
98.6 24 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: crystal structure of the editing domain of threonyl-trna2 synthetase complexed with serine
18c2dwqB_
98.4 33 PDB header:hydrolase
Chain: B: PDB Molecule:gtp-binding protein;
PDBTitle: thermus thermophilus ychf gtp-binding protein
19d1sc6a3
98.3 23 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
20c2ohfA_
98.2 18 PDB header:hydrolase
Chain: A: PDB Molecule:gtp-binding protein 9;
PDBTitle: crystal structure of human ola1 in complex with amppcp
21c1wxqA_
not modelled 98.2 26 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:gtp-binding protein;
PDBTitle: crystal structure of gtp binding protein from pyrococcus horikoshii2 ot3
22d1ygya3
not modelled 98.2 22 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
23d2f1fa1
not modelled 98.2 16 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:IlvH-like
24d2fgca2
not modelled 98.1 9 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:IlvH-like
25d2pc6a2
not modelled 98.1 11 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:IlvH-like
26c1jalA_
not modelled 98.0 31 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:ychf protein;
PDBTitle: ychf protein (hi0393)
27c2pc6C_
not modelled 98.0 11 PDB header:lyase
Chain: C: PDB Molecule:probable acetolactate synthase isozyme iii (small subunit);
PDBTitle: crystal structure of putative acetolactate synthase- small subunit2 from nitrosomonas europaea
28c2fgcA_
not modelled 97.9 10 PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase, small subunit;
PDBTitle: crystal structure of acetolactate synthase- small subunit from2 thermotoga maritima
29c1ni3A_
not modelled 97.9 24 PDB header:hydrolase
Chain: A: PDB Molecule:ychf gtp-binding protein;
PDBTitle: structure of the schizosaccharomyces pombe ychf gtpase
30c2f1fA_
not modelled 97.9 16 PDB header:transferase
Chain: A: PDB Molecule:acetolactate synthase isozyme iii small subunit;
PDBTitle: crystal structure of the regulatory subunit of2 acetohydroxyacid synthase isozyme iii from e. coli
31c1nyqA_
not modelled 97.9 25 PDB header:ligase
Chain: A: PDB Molecule:threonyl-trna synthetase 1;
PDBTitle: structure of staphylococcus aureus threonyl-trna synthetase2 complexed with an analogue of threonyl adenylate
32c1qf6A_
not modelled 97.8 26 PDB header:ligase/rna
Chain: A: PDB Molecule:threonyl-trna synthetase;
PDBTitle: structure of e. coli threonyl-trna synthetase complexed with its2 cognate trna
33d1zpva1
not modelled 97.6 14 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:SP0238-like
34c1u8sB_
not modelled 97.5 14 PDB header:transcription
Chain: B: PDB Molecule:glycine cleavage system transcriptional
PDBTitle: crystal structure of putative glycine cleavage system2 transcriptional repressor
35c2nyiB_
97.5 16 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:unknown protein;
PDBTitle: crystal structure of an unknown protein from galdieria2 sulphuraria
36c3n0vD_
not modelled 97.5 12 PDB header:hydrolase
Chain: D: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pp_0327)2 from pseudomonas putida kt2440 at 2.25 a resolution
37c1y7pB_
not modelled 97.4 25 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:hypothetical protein af1403;
PDBTitle: 1.9 a crystal structure of a protein of unknown function2 af1403 from archaeoglobus fulgidus, probable metabolic3 regulator
38d1u8sa1
not modelled 97.2 20 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Glycine cleavage system transcriptional repressor
39c3nrbD_
not modelled 97.1 17 PDB header:hydrolase
Chain: D: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution
40c1ygyA_
not modelled 97.0 22 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of d-3-phosphoglycerate dehydrogenase from2 mycobacterium tuberculosis
41c1ybaC_
not modelled 97.0 24 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: the active form of phosphoglycerate dehydrogenase
42c3o1lB_
not modelled 96.9 14 PDB header:hydrolase
Chain: B: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution
43c3k5pA_
not modelled 96.9 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of amino acid-binding act: d-isomer specific 2-2 hydroxyacid dehydrogenase catalytic domain from brucella melitensis
44c3obiC_
not modelled 96.6 20 PDB header:hydrolase
Chain: C: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (np_949368)2 from rhodopseudomonas palustris cga009 at 1.95 a resolution
45c3louB_
not modelled 96.6 8 PDB header:hydrolase
Chain: B: PDB Molecule:formyltetrahydrofolate deformylase;
PDBTitle: crystal structure of formyltetrahydrofolate deformylase (yp_105254.1)2 from burkholderia mallei atcc 23344 at 1.90 a resolution
46d2f06a2
not modelled 96.3 16 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:BT0572-like
47d1rwua_
not modelled 96.1 9 Fold:Ferredoxin-like
Superfamily:YbeD/HP0495-like
Family:YbeD-like
48c1rwuA_
not modelled 96.1 9 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical upf0250 protein ybed;
PDBTitle: solution structure of conserved protein ybed from e. coli
49d1phza1
not modelled 96.0 13 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Phenylalanine metabolism regulatory domain
50d1zud21
not modelled 95.7 23 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS
51c2qmxB_
not modelled 95.6 11 PDB header:ligase
Chain: B: PDB Molecule:prephenate dehydratase;
PDBTitle: the crystal structure of l-phe inhibited prephenate dehydratase from2 chlorobium tepidum tls
52c2f06B_
not modelled 95.4 18 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of protein bt0572 from bacteroides thetaiotaomicron
53d2qmwa2
not modelled 95.3 17 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:Phenylalanine metabolism regulatory domain
54d2hj1a1
not modelled 95.1 28 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:HI0395-like
55c2hj1A_
not modelled 95.1 28 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of a 3d domain-swapped dimer of protein hi0395 from2 haemophilus influenzae
56c2phmA_
not modelled 95.1 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:protein (phenylalanine-4-hydroxylase);
PDBTitle: structure of phenylalanine hydroxylase dephosphorylated
57c3mwbA_
not modelled 95.0 22 PDB header:lyase
Chain: A: PDB Molecule:prephenate dehydratase;
PDBTitle: the crystal structure of prephenate dehydratase in complex with l-phe2 from arthrobacter aurescens to 2.0a
58c3mtjA_
not modelled 94.7 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:homoserine dehydrogenase;
PDBTitle: the crystal structure of a homoserine dehydrogenase from thiobacillus2 denitrificans to 2.15a
59d2f06a1
not modelled 94.5 20 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:BT0572-like
60c3cwiA_
not modelled 93.9 9 PDB header:biosynthetic protein
Chain: A: PDB Molecule:thiamine-biosynthesis protein this;
PDBTitle: crystal structure of thiamine biosynthesis protein (this)2 from geobacter metallireducens. northeast structural3 genomics consortium target gmr137
61c3luyA_
not modelled 93.8 14 PDB header:isomerase
Chain: A: PDB Molecule:probable chorismate mutase;
PDBTitle: putative chorismate mutase from bifidobacterium adolescentis
62d1tygb_
not modelled 93.8 19 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS
63c1tygG_
not modelled 92.2 19 PDB header:biosynthetic protein
Chain: G: PDB Molecule:yjbs;
PDBTitle: structure of the thiazole synthase/this complex
64d1vjka_
not modelled 91.8 22 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:MoaD
65c2kl0A_
not modelled 91.8 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative thiamin biosynthesis this;
PDBTitle: solution nmr structure of rhodopseudomonas palustris rpa3574,2 northeast structural genomics consortium (nesg) target rpr325
66c2qieB_
not modelled 91.6 14 PDB header:transferase
Chain: B: PDB Molecule:molybdopterin synthase small subunit;
PDBTitle: staphylococcus aureus molybdopterin synthase in complex2 with precursor z
67c1tdjA_
not modelled 91.6 16 PDB header:allostery
Chain: A: PDB Molecule:biosynthetic threonine deaminase;
PDBTitle: threonine deaminase (biosynthetic) from e. coli
68d2cu3a1
not modelled 91.4 18 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS
69c3po0A_
not modelled 90.8 16 PDB header:protein binding
Chain: A: PDB Molecule:small archaeal modifier protein 1;
PDBTitle: crystal structure of samp1 from haloferax volcanii
70c2qmwA_
not modelled 90.4 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:prephenate dehydratase;
PDBTitle: the crystal structure of the prephenate dehydratase (pdt) from2 staphylococcus aureus subsp. aureus mu50
71c2dqbB_
not modelled 90.3 28 PDB header:hydrolase, dna binding protein
Chain: B: PDB Molecule:deoxyguanosinetriphosphate triphosphohydrolase, putative;
PDBTitle: crystal structure of dntp triphosphohydrolase from thermus2 thermophilus hb8, which is homologous to dgtp triphosphohydrolase
72d1y7pa2
not modelled 90.0 25 Fold:Ferredoxin-like
Superfamily:ACT-like
Family:AF1403 N-terminal domain-like
73c1dm9A_
not modelled 88.6 4 PDB header:structural genomics
Chain: A: PDB Molecule:hypothetical 15.5 kd protein in mrca-pcka
PDBTitle: heat shock protein 15 kd
74d1dm9a_
not modelled 88.6 4 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Heat shock protein 15 kD
75d2qgsa1
not modelled 88.5 14 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
76c2ogiA_
not modelled 87.3 21 PDB header:hydrolase
Chain: A: PDB Molecule:hypothetical protein sag1661;
PDBTitle: crystal structure of a putative metal dependent phosphohydrolase2 (sag1661) from streptococcus agalactiae serogroup v at 1.85 a3 resolution
77c2dtjA_
not modelled 86.9 19 PDB header:transferase
Chain: A: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of regulatory subunit of aspartate kinase2 from corynebacterium glutamicum
78d1jala2
not modelled 86.2 31 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:G domain-linked domain
79c2o08B_
not modelled 86.2 19 PDB header:hydrolase
Chain: B: PDB Molecule:bh1327 protein;
PDBTitle: crystal structure of a putative hd superfamily hydrolase (bh1327) from2 bacillus halodurans at 1.90 a resolution
80c3ccgA_
not modelled 85.4 14 PDB header:hydrolase
Chain: A: PDB Molecule:hd superfamily hydrolase;
PDBTitle: crystal structure of predicted hd superfamily hydrolase involved in2 nad metabolism (np_347894.1) from clostridium acetobutylicum at 1.503 a resolution
81c2k6pA_
not modelled 84.8 18 PDB header:unknown function
Chain: A: PDB Molecule:uncharacterized protein hp_1423;
PDBTitle: solution structure of hypothetical protein, hp1423
82d2piea1
not modelled 84.5 19 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
83d1fm0d_
not modelled 83.4 24 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:MoaD
84c3gqsB_
not modelled 82.0 17 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:adenylate cyclase-like protein;
PDBTitle: crystal structure of the fha domain of ct664 protein from chlamydia2 trachomatis
85d1ni3a2
not modelled 81.8 21 Fold:beta-Grasp (ubiquitin-like)
Superfamily:TGS-like
Family:G domain-linked domain
86d2cyya2
not modelled 80.5 19 Fold:Ferredoxin-like
Superfamily:Dimeric alpha+beta barrel
Family:Lrp/AsnC-like transcriptional regulator C-terminal domain
87c3fm8A_
not modelled 80.1 30 PDB header:transport protein/hydrolase activator
Chain: A: PDB Molecule:kinesin-like protein kif13b;
PDBTitle: crystal structure of full length centaurin alpha-1 bound with the fha2 domain of kif13b (capri target)
88c3p96A_
not modelled 79.9 18 PDB header:hydrolase
Chain: A: PDB Molecule:phosphoserine phosphatase serb;
PDBTitle: crystal structure of phosphoserine phosphatase serb from mycobacterium2 avium, native form
89d3djba1
not modelled 79.1 18 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
90d1rwsa_
not modelled 79.0 35 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:ThiS
91d2joqa1
not modelled 77.7 9 Fold:Ferredoxin-like
Superfamily:YbeD/HP0495-like
Family:HP0495-like
92d3b57a1
not modelled 77.6 21 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
93c3l76B_
not modelled 77.0 15 PDB header:transferase
Chain: B: PDB Molecule:aspartokinase;
PDBTitle: crystal structure of aspartate kinase from synechocystis
94c2g1eA_
not modelled 76.7 13 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ta0895;
PDBTitle: solution structure of ta0895
95c2eh0A_
not modelled 76.2 26 PDB header:transport protein
Chain: A: PDB Molecule:kinesin-like protein kif1b;
PDBTitle: solution structure of the fha domain from human kinesin-2 like protein kif1b
96d1c06a_
not modelled 75.1 23 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Ribosomal protein S4
97d2g1la1
not modelled 75.0 22 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
98c2bs2E_
not modelled 74.0 21 PDB header:oxidoreductase
Chain: E: PDB Molecule:quinol-fumarate reductase iron-sulfur subunit b;
PDBTitle: quinol:fumarate reductase from wolinella succinogenes
99d2fug33
not modelled 73.3 22 Fold:beta-Grasp (ubiquitin-like)
Superfamily:2Fe-2S ferredoxin-like
Family:2Fe-2S ferredoxin domains from multidomain proteins
100d1yjma1
not modelled 72.9 21 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
101c2re1A_
not modelled 72.9 14 PDB header:transferase
Chain: A: PDB Molecule:aspartokinase, alpha and beta subunits;
PDBTitle: crystal structure of aspartokinase alpha and beta subunits
102c3bbnD_
not modelled 72.4 32 PDB header:ribosome
Chain: D: PDB Molecule:ribosomal protein s4;
PDBTitle: homology model for the spinach chloroplast 30s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome.
103c2qjlA_
not modelled 72.2 26 PDB header:signaling protein
Chain: A: PDB Molecule:ubiquitin-related modifier 1;
PDBTitle: crystal structure of urm1
104c3mzoA_
not modelled 71.8 7 PDB header:hydrolase
Chain: A: PDB Molecule:lin2634 protein;
PDBTitle: crystal structure of a hd-domain phosphohydrolase (lin2634) from2 listeria innocua at 1.98 a resolution
105d1xo3a_
not modelled 71.3 36 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:C9orf74 homolog
106c2jqlA_
not modelled 71.0 35 PDB header:cell cycle
Chain: A: PDB Molecule:dna damage response protein kinase dun1;
PDBTitle: nmr structure of the yeast dun1 fha domain in complex with2 a doubly phosphorylated (pt) peptide derived from rad533 scd1
107d1gxca_
not modelled 70.7 17 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
108c1gxcA_
not modelled 70.7 17 PDB header:phosphoprotein-binding domain
Chain: A: PDB Molecule:serine/threonine-protein kinase chk2;
PDBTitle: fha domain from human chk2 kinase in complex with a2 synthetic phosphopeptide
109d2uubd1
not modelled 70.5 32 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Ribosomal protein S4
110d2heka1
not modelled 70.5 24 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
111d2pq7a1
not modelled 69.4 15 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
112d1p9ka_
not modelled 69.2 14 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:YbcJ-like
113c3dwmA_
not modelled 68.9 15 PDB header:transferase
Chain: A: PDB Molecule:9.5 kda culture filtrate antigen cfp10a;
PDBTitle: crystal structure of mycobacterium tuberculosis cyso, an antigen
114d1g3ga_
not modelled 68.2 30 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
115d1dmza_
not modelled 68.2 23 Fold:SMAD/FHA domain
Superfamily:SMAD/FHA domain
Family:FHA domain
116c3kt9A_
not modelled 68.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:aprataxin;
PDBTitle: aprataxin fha domain
117d3dtoa1
not modelled 68.0 20 Fold:HD-domain/PDEase-like
Superfamily:HD-domain/PDEase-like
Family:HD domain
118d1vioa2
not modelled 67.5 36 Fold:Alpha-L RNA-binding motif
Superfamily:Alpha-L RNA-binding motif
Family:Pseudouridine synthase RsuA N-terminal domain
119d1wgka_
not modelled 67.2 25 Fold:beta-Grasp (ubiquitin-like)
Superfamily:MoaD/ThiS
Family:C9orf74 homolog
120c3hx1B_
not modelled 67.1 36 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:slr1951 protein;
PDBTitle: crystal structure of the slr1951 protein from synechocystis sp.2 northeast structural genomics consortium target sgr167a

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0