Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	E	N	Y	L	I	D	N	L	D	R	G	I	L	E	A	L	M	G	N	A	R	T	A	Y	A	E	L	A	K	Q	F	G	V	S	P	G	T	I	H	V	R	V	E	K	M	K	Q	A	G	I	I	T	G	A	R	I	D	V	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	K	Q	L	G	Y	D	V	G	C	F	I	G	I	I	L	K	S	A	K	D	Y	P	S	A	L	A	K	L	E	S	L	D	E	V	T	E	A	Y	Y	T	T	G	H	Y	S	I	F	I	K	V	M	C	R	S	I	D	A	L	Q
Secondary structure
SS confidence
Disorder																		?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
Sequence		H	V	L	I	N	K	I	Q	T	I	D	E	I	Q	S	T	E	T	L	I	V	L	Q	N	P	I	M	R	T	I	K	P
Secondary structure
SS confidence
Disorder										?														?		?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2cg4 chain B Region: 4 - 152 Aligned: 149 Modelled: 149 Confidence: 100.0% Identity: 99% PDB header:transcription Chain: B: PDB Molecule:regulatory protein asnc; PDBTitle: structure of e.coli asnc Phyre2 PDB 2e7x chain A Region: 6 - 152 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 20% PDB header:transcription regulator Chain: A: PDB Molecule:150aa long hypothetical transcriptional regulator; PDBTitle: structure of the lrp/asnc like transcriptional regulator from2 sulfolobus tokodaii 7 complexed with its cognate ligand Phyre2 PDB 2p6t chain H Region: 6 - 152 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 22% PDB header:transcription Chain: H: PDB Molecule:transcriptional regulator, lrp/asnc family; PDBTitle: crystal structure of transcriptional regulator nmb0573 and l-leucine2 complex from neisseria meningitidis Phyre2 PDB 2gqq chain B Region: 6 - 152 Aligned: 147 Modelled: 147 Confidence: 100.0% Identity: 22% PDB header:transcription Chain: B: PDB Molecule:leucine-responsive regulatory protein; PDBTitle: crystal structure of e. coli leucine-responsive regulatory protein2 (lrp) Phyre2 PDB 2e1c chain A Region: 5 - 152 Aligned: 146 Modelled: 148 Confidence: 100.0% Identity: 29% PDB header:transcription/dna Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph1519; PDBTitle: structure of putative hth-type transcriptional regulator ph1519/dna2 complex Phyre2 PDB 1i1g chain A Region: 6 - 146 Aligned: 140 Modelled: 141 Confidence: 100.0% Identity: 31% PDB header:transcription Chain: A: PDB Molecule:transcriptional regulator lrpa; PDBTitle: crystal structure of the lrp-like transcriptional regulator from the2 archaeon pyrococcus furiosus Phyre2 PDB 2dbb chain A Region: 5 - 148 Aligned: 143 Modelled: 144 Confidence: 100.0% Identity: 21% PDB header:transcriptional regulator Chain: A: PDB Molecule:putative hth-type transcriptional regulator ph0061; PDBTitle: crystal structure of ph0061 Phyre2 PDB 2cfx chain D Region: 4 - 148 Aligned: 140 Modelled: 145 Confidence: 100.0% Identity: 24% PDB header:transcription Chain: D: PDB Molecule:hth-type transcriptional regulator lrpc; PDBTitle: structure of b.subtilis lrpc Phyre2 PDB 3i4p chain A Region: 7 - 152 Aligned: 145 Modelled: 146 Confidence: 100.0% Identity: 26% PDB header:transcription regulator Chain: A: PDB Molecule:transcriptional regulator, asnc family; PDBTitle: crystal structure of asnc family transcriptional regulator from2 agrobacterium tumefaciens Phyre2 PDB 2vbz chain A Region: 6 - 152 Aligned: 146 Modelled: 147 Confidence: 100.0% Identity: 26% PDB header:dna-binding protein Chain: A: PDB Molecule:transcriptional regulatory protein; PDBTitle: feast or famine regulatory protein (rv3291c)from m.2 tuberculosis complexed with l-tryptophan Phyre2 PDB 2ia0 chain A Region: 5 - 147 Aligned: 142 Modelled: 143 Confidence: 100.0% Identity: 22% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative hth-type transcriptional regulator pf0864; PDBTitle: transcriptional regulatory protein pf0864 from pyrococcus furiosus a2 member of the asnc family (pf0864) Phyre2 PDB 2cg4 chain A domain 1 Region: 4 - 66 Aligned: 63 Modelled: 63 Confidence: 99.7% Identity: 98% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Lrp/AsnC-like transcriptional regulator N-terminal domain Phyre2 PDB 2cg4 chain A domain 2 Region: 68 - 152 Aligned: 85 Modelled: 85 Confidence: 99.7% Identity: 100% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Lrp/AsnC-like transcriptional regulator C-terminal domain Phyre2 PDB 2cfx chain A domain 1 Region: 4 - 66 Aligned: 63 Modelled: 63 Confidence: 99.7% Identity: 30% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Lrp/AsnC-like transcriptional regulator N-terminal domain Phyre2 PDB 2cyy chain A domain 1 Region: 6 - 65 Aligned: 60 Modelled: 60 Confidence: 99.6% Identity: 28% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Lrp/AsnC-like transcriptional regulator N-terminal domain Phyre2 PDB 1i1g chain A domain 1 Region: 6 - 65 Aligned: 60 Modelled: 60 Confidence: 99.6% Identity: 43% Fold: DNA/RNA-binding 3-helical bundle Superfamily: "Winged helix" DNA-binding domain Family: Lrp/AsnC-like transcriptional regulator N-terminal domain Phyre2 PDB 2cyy chain A domain 2 Region: 66 - 152 Aligned: 85 Modelled: 87 Confidence: 99.6% Identity: 29% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Lrp/AsnC-like transcriptional regulator C-terminal domain Phyre2 PDB 1i1g chain A domain 2 Region: 66 - 146 Aligned: 80 Modelled: 81 Confidence: 99.6% Identity: 23% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Lrp/AsnC-like transcriptional regulator C-terminal domain Phyre2 PDB 2l4a chain A Region: 5 - 60 Aligned: 56 Modelled: 56 Confidence: 99.5% Identity: 32% PDB header:dna binding protein Chain: A: PDB Molecule:leucine responsive regulatory protein; PDBTitle: nmr structure of the dna-binding domain of e.coli lrp Phyre2 PDB 2zbc chain H Region: 68 - 145 Aligned: 77 Modelled: 78 Confidence: 99.5% Identity: 27% PDB header:transcription Chain: H: PDB Molecule:83aa long hypothetical transcriptional regulator asnc; PDBTitle: crystal structure of sts042, a stand-alone ram module protein, from2 hyperthermophilic archaeon sulfolobus tokodaii strain7. Phyre2 1 c2cg4B_ 2 c2e7xA_ 3 c2p6tH_ 4 c2gqqB_ 5 c2e1cA_ 6 c1i1gA_ 7 c2dbbA_ 8 c2cfxD_ 9 c3i4pA_ 10 c2vbzA_ 11 c2ia0A_ 12 d2cg4a1 13 d2cg4a2 14 d2cfxa1 15 d2cyya1 16 d1i1ga1 17 d2cyya2 18 d1i1ga2 19 c2l4aA_ 20 c2zbcH_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 425 426 427 428 429 430 431 432 433 434 435 436 437 438 439 440 441 442 443 444 445 446 447 448 449 450 451 452 453 454 455 456 457 458 459 460 461 462 463 464 465 466 467 468 469 470 471 472 473 474 475 476 477 478 479 480 481 482 483 484 485 486 487 488 489 490 491 492 493 494 495 496 497 498 499