Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	F	T	S	S	C	C	D	N	L	S	I	D	E	I	I	E	R	A	E	K	G	D	C	E	A	Q	Y	I	V	G	F	Y	Y	N	R	D	S	A	I	D	S	P	D	D	E	K	A	F	Y	W	L	K	L	A	A	E	Q	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		H	C	E	A	Q	Y	S	L	G	Q	K	Y	T	E	D	K	S	R	H	K	D	N	E	Q	A	I	F	W	L	K	K	A	A	L	Q	G	H	T	F	A	S	N	A	L	G	W	T	L	D	R	G	E	A	P	N	Y	K	E	A	V
Secondary structure
SS confidence
Disorder																																						?															?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		V	W	Y	Q	I	A	A	E	S	G	M	S	Y	A	Q	N	N	L	G	W	M	Y	R	N	G	N	G	V	A	K	D	Y	A	L	A	F	F	W	Y	K	Q	A	A	L	Q	G	H	S	D	A	Q	N	N	L	A	D	L	Y	E	D
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		G	K	G	V	A	Q	N	K	T	L	A	A	F	W	Y	L	K	S	A	Q	Q	G	N	R	H	A	Q	F	Q	I	A	W	D	Y	N	A	G	E	G	V	D	Q	D	Y	K	Q	A	M	Y	W	Y	L	K	A	A	A	Q	G	S	V
Secondary structure
SS confidence
Disorder																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	A	Y	V	N	I	G	Y	M	Y	K	H	G	Q	G	V	E	K	D	Y	Q	A	A	F	E	W	F	T	K	A	A	E	C	N	D	A	T	A	W	Y	N	L	A	I	M	Y	H	Y	G	E	G	R	P	V	D	L	R	Q	A	L
Secondary structure
SS confidence
Disorder																																			?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.
Sequence		D	L	Y	R	K	V	Q	S	S	G	T	R	D	V	S	Q	E	I	R	E	T	E	D	L	L
Secondary structure
SS confidence
Disorder												?													?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2xm6 chain A Region: 13 - 325 Aligned: 312 Modelled: 313 Confidence: 100.0% Identity: 34% PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain Phyre2 PDB 1ouv chain A Region: 24 - 321 Aligned: 259 Modelled: 264 Confidence: 100.0% Identity: 22% Fold: alpha-alpha superhelix Superfamily: HCP-like Family: HCP-like Phyre2 PDB 3e4b chain D Region: 4 - 325 Aligned: 175 Modelled: 179 Confidence: 100.0% Identity: 34% PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r Phyre2 PDB 3rjv chain A Region: 12 - 323 Aligned: 204 Modelled: 209 Confidence: 99.9% Identity: 30% PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution Phyre2 PDB 1klx chain A Region: 38 - 318 Aligned: 132 Modelled: 133 Confidence: 99.8% Identity: 24% Fold: alpha-alpha superhelix Superfamily: HCP-like Family: HCP-like Phyre2 PDB 3hym chain B Region: 24 - 325 Aligned: 291 Modelled: 299 Confidence: 98.9% Identity: 8% PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure Phyre2 PDB 2y4t chain A Region: 10 - 325 Aligned: 307 Modelled: 311 Confidence: 98.8% Identity: 10% PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) Phyre2 PDB 3ieg chain B Region: 10 - 325 Aligned: 307 Modelled: 316 Confidence: 98.8% Identity: 11% PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a Phyre2 PDB 1w3b chain A Region: 10 - 325 Aligned: 307 Modelled: 311 Confidence: 98.6% Identity: 12% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2xpi chain A Region: 10 - 320 Aligned: 161 Modelled: 170 Confidence: 98.4% Identity: 19% PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 Phyre2 PDB 2gw1 chain A Region: 10 - 308 Aligned: 290 Modelled: 294 Confidence: 98.4% Identity: 16% PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 Phyre2 PDB 1fch chain B Region: 10 - 308 Aligned: 213 Modelled: 217 Confidence: 98.4% Identity: 17% PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 Phyre2 PDB 3pe3 chain D Region: 24 - 325 Aligned: 145 Modelled: 154 Confidence: 98.1% Identity: 19% PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate Phyre2 PDB 2ho1 chain B Region: 25 - 320 Aligned: 209 Modelled: 213 Confidence: 98.1% Identity: 16% PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf Phyre2 PDB 1xnf chain A Region: 1 - 323 Aligned: 202 Modelled: 211 Confidence: 98.1% Identity: 15% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2q7f chain A Region: 12 - 319 Aligned: 185 Modelled: 194 Confidence: 98.0% Identity: 18% PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site Phyre2 PDB 3sf4 chain B Region: 10 - 325 Aligned: 307 Modelled: 316 Confidence: 98.0% Identity: 11% PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn Phyre2 PDB 2vq2 chain A Region: 25 - 318 Aligned: 208 Modelled: 217 Confidence: 97.9% Identity: 12% PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor Phyre2 PDB 2pl2 chain A Region: 26 - 321 Aligned: 184 Modelled: 193 Confidence: 97.9% Identity: 23% PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 Phyre2 PDB 1fch chain A Region: 10 - 308 Aligned: 212 Modelled: 216 Confidence: 97.9% Identity: 14% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 1 c2xm6A_ 2 d1ouva_ 3 c3e4bD_ 4 c3rjvA_ 5 d1klxa_ 6 c3hymB_ 7 c2y4tA_ 8 c3iegB_ 9 d1w3ba_ 10 c2xpiA_ 11 c2gw1A_ 12 c1fchB_ 13 c3pe3D_ 14 c2ho1B_ 15 d1xnfa_ 16 c2q7fA_ 17 c3sf4B_ 18 c2vq2A_ 19 c2pl2A_ 20 d1fcha_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2xm6A_ 100.0 34 PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain 2 d1ouva_ 100.0 22 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 3 c3e4bD_ 100.0 34 PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r 4 c3rjvA_ 99.9 30 PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution 5 d1klxa_ 99.8 24 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 6 c3hymB_ 98.9 8 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 7 c2y4tA_ 98.8 10 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 8 c3iegB_ 98.8 11 PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a 9 d1w3ba_ 98.6 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 10 c2xpiA_ 98.4 19 PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 11 c2gw1A_ 98.4 16 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 12 c1fchB_ 98.4 17 PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 13 c3pe3D_ 98.1 19 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 14 c2ho1B_ 98.1 16 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 15 d1xnfa_ 98.1 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 16 c2q7fA_ 98.0 18 PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site 17 c3sf4B_ 98.0 11 PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn 18 c2vq2A_ 97.9 12 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 19 c2pl2A_ 97.9 23 PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 20 d1fcha_ 97.9 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 21 c3as5A_ not modelled 97.8 20 PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 22 c3cvpA_ not modelled 97.8 15 PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) 23 c3urzB_ not modelled 97.7 12 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 24 d1tjca_ not modelled 97.7 20 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 25 c2ifuA_ not modelled 97.5 13 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio 26 d1y8ma1 not modelled 97.4 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 27 d1hxia_ not modelled 97.4 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 28 c3draA_ not modelled 97.4 7 PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp 29 d1dcea1 not modelled 97.4 5 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 30 c3q15A_ not modelled 97.3 12 PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f 31 c2katA_ not modelled 97.3 13 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 32 c3nf1A_ not modelled 97.2 12 PDB header:motor protein, transport protein Chain: A: PDB Molecule:kinesin light chain 1; PDBTitle: crystal structure of the tpr domain of kinesin light chain 1 33 c2e2eA_ not modelled 97.0 21 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 34 d1iyga_ not modelled 96.9 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 35 c2xcbA_ not modelled 96.9 8 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 36 c2c2lD_ not modelled 96.9 14 PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase 37 c1wao4_ not modelled 96.9 12 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 38 c3k9iA_ not modelled 96.8 12 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 39 c3ulqA_ not modelled 96.8 13 PDB header:gene regulation/transcription activator Chain: A: PDB Molecule:response regulator aspartate phosphatase f; PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain 40 c3fp4A_ not modelled 96.8 17 PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment 41 d2buga1 not modelled 96.8 25 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 42 c1ihgA_ not modelled 96.7 25 PDB header:isomerase Chain: A: PDB Molecule:cyclophilin 40; PDBTitle: bovine cyclophilin 40, monoclinic form 43 d1elwa_ not modelled 96.7 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 44 d1pc2a_ not modelled 96.6 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 45 c2dbaA_ not modelled 96.6 23 PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 46 c3gyzB_ not modelled 96.6 11 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 47 c2kckA_ not modelled 96.6 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tpr repeat; PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a 48 d1nzna_ not modelled 96.5 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 49 c3beeB_ not modelled 96.5 10 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 50 c2kc7A_ not modelled 96.5 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bfr218_protein; PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218 51 c1na3A_ not modelled 96.4 25 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 52 c2kcvA_ not modelled 96.4 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 53 c2vsnB_ not modelled 96.1 9 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 54 d1zu2a1 not modelled 96.1 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 55 c1kt0A_ not modelled 96.1 16 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 56 d1p5qa1 not modelled 96.0 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 57 c3fflC_ not modelled 96.0 14 PDB header:cell cycle Chain: C: PDB Molecule:anaphase-promoting complex subunit 7; PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7 58 c3q75A_ not modelled 95.9 7 PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide 59 d2pqrb1 not modelled 95.9 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 60 c2xevB_ not modelled 95.8 16 PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf 61 c2avpA_ not modelled 95.7 38 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix 62 c2if4A_ not modelled 95.7 24 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 63 d1hh8a_ not modelled 95.7 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 64 c1qz2B_ not modelled 95.6 17 PDB header:isomerase/chaperone Chain: B: PDB Molecule:fk506-binding protein 4; PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90 65 d1kt1a1 not modelled 95.5 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 66 d2c2la1 not modelled 95.2 14 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 67 c2l6jA_ not modelled 95.1 12 PDB header:protein binding Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90; PDBTitle: tah1 complexed by meevd 68 c3ceqB_ not modelled 95.0 22 PDB header:motor protein, transport protein Chain: B: PDB Molecule:kinesin light chain 2; PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2) 69 c3qkyA_ not modelled 94.7 15 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd 70 d1elra_ not modelled 94.6 25 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 71 d2fbna1 not modelled 94.6 25 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 72 c2fbnA_ not modelled 94.6 25 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative; PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain 73 c3ly8A_ not modelled 94.4 10 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 74 d1ihga1 not modelled 94.3 25 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 75 c2vyiA_ not modelled 94.3 12 PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt 76 c2r5sB_ not modelled 94.0 11 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 77 c3mkrA_ not modelled 93.5 16 PDB header:transport protein Chain: A: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat 78 c2vgxA_ not modelled 93.3 8 PDB header:chaperone Chain: A: PDB Molecule:chaperone sycd; PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd 79 d1qsaa1 not modelled 92.9 10 Fold:alpha-alpha superhelix Superfamily:Bacterial muramidases Family:Bacterial muramidases 80 d1a17a_ not modelled 92.2 22 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 81 c3rkvA_ not modelled 90.9 13 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 82 c3gw4B_ not modelled 90.2 17 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. 83 c2hyzA_ not modelled 89.3 38 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) 84 d1d8da_ not modelled 88.3 12 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 85 d2hr2a1 not modelled 86.9 22 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:CT2138-like 86 c3sz7A_ not modelled 85.1 18 PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus 87 d2ooea1 not modelled 85.0 5 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 88 c3oxgA_ not modelled 84.6 13 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii) 89 d1zbpa1 not modelled 84.1 16 Fold:ImpE-like Superfamily:ImpE-like Family:ImpE-like 90 d1hz4a_ not modelled 84.0 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Transcription factor MalT domain III 91 d1qqea_ not modelled 83.7 12 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 92 c2uy1A_ not modelled 83.5 12 PDB header:rna-binding protein Chain: A: PDB Molecule:cleavage stimulation factor 77; PDBTitle: crystal structure of cstf-77 93 c3q49B_ not modelled 83.4 14 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 94 c3mv3B_ not modelled 83.0 8 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 95 c1slyA_ not modelled 77.9 10 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 96 c1tnoI_ not modelled 76.8 12 PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b 97 c3mekA_ not modelled 74.7 13 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine 98 c2yhcA_ not modelled 70.0 10 PDB header:membrane protein Chain: A: PDB Molecule:upf0169 lipoprotein yfio; PDBTitle: structure of bamd from e. coli 99 c3qwvA_ not modelled 69.6 23 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 2; PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy 100 c1xi4D_ not modelled 66.6 8 PDB header:endocytosis/exocytosis Chain: D: PDB Molecule:clathrin heavy chain; PDBTitle: clathrin d6 coat 101 c3n71A_ not modelled 64.0 10 PDB header:transcription Chain: A: PDB Molecule:histone lysine methyltransferase smyd1; PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1 102 d1ya0a1 not modelled 62.0 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 103 c3qtmB_ not modelled 52.4 14 PDB header:translation Chain: B: PDB Molecule:uncharacterized protein c4b3.07; PDBTitle: structure of a yeast protein 104 c3qdnA_ not modelled 51.8 9 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 105 d1wy6a1 not modelled 48.3 19 Fold:alpha-alpha superhelix Superfamily:Hypothetical protein ST1625 Family:Hypothetical protein ST1625 106 c2hz8A_ not modelled 39.9 32 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed diiron protein; PDBTitle: qm/mm structure refined from nmr-structure of a single2 chain diiron protein 107 d2ff4a2 not modelled 32.9 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:BTAD-like 108 d1wfda_ not modelled 31.0 35 Fold:Spectrin repeat-like Superfamily:MIT domain Family:MIT domain 109 d1wr0a1 not modelled 29.2 26 Fold:Spectrin repeat-like Superfamily:MIT domain Family:MIT domain 110 d2jq9a1 not modelled 21.4 30 Fold:Spectrin repeat-like Superfamily:MIT domain Family:MIT domain 111 c2w2uA_ not modelled 20.7 19 PDB header:hydrolase/transport Chain: A: PDB Molecule:hypothetical p60 katanin; PDBTitle: structural insight into the interaction between archaeal2 escrt-iii and aaa-atpase

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0