Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	A	V	T	Q	T	A	Q	A	C	D	L	V	I	F	G	A	K	G	D	L	A	R	R	K	L	L	P	S	L	Y	Q	L	E	K	A	G	Q	L	N	P	D	T	R	I	I	G	V	G	R	A	D	W	D	K	A	A	Y	T	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		V	V	R	E	A	L	E	T	F	M	K	E	T	I	D	E	G	L	W	D	T	L	S	A	R	L	D	F	C	N	L	D	V	N	D	T	A	A	F	S	R	L	G	A	M	L	D	Q	K	N	R	I	T	I	N	Y	F	A	M	P
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		P	S	T	F	G	A	I	C	K	G	L	G	E	A	K	L	N	A	K	P	A	R	V	V	M	E	K	P	L	G	T	S	L	A	T	S	Q	E	I	N	D	Q	V	G	E	Y	F	E	E	C	Q	V	Y	R	I	D	H	Y	L	G
Secondary structure
SS confidence
Disorder																?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		K	E	T	V	L	N	L	L	A	L	R	F	A	N	S	L	F	V	N	N	W	D	N	R	T	I	D	H	V	E	I	T	V	A	E	E	V	G	I	E	G	R	W	G	Y	F	D	K	A	G	Q	M	R	D	M	I	Q	N	H	L
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	Q	I	L	C	M	I	A	M	S	P	P	S	D	L	S	A	D	S	I	R	D	E	K	V	K	V	L	K	S	L	R	R	I	D	R	S	N	V	R	E	K	T	V	R	G	Q	Y	T	A	G	F	A	Q	G	K	K	V	P	G
Secondary structure
SS confidence
Disorder																	?																																		?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		Y	L	E	E	E	G	A	N	K	S	S	N	T	E	T	F	V	A	I	R	V	D	I	D	N	W	R	W	A	G	V	P	F	Y	L	R	T	G	K	R	L	P	T	K	C	S	E	V	V	V	Y	F	K	T	P	E	L	N	L	F
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		K	E	S	W	Q	D	L	P	Q	N	K	L	T	I	R	L	Q	P	D	E	G	V	D	I	Q	V	L	N	K	V	P	G	L	D	H	K	H	N	L	Q	I	T	K	L	D	L	S	Y	S	E	T	F	N	Q	T	H	L	A	D	A
Secondary structure
SS confidence
Disorder				?	?	?																												?	?	?	?	?		?												?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		Y	E	R	L	L	L	E	T	M	R	G	I	Q	A	L	F	V	R	R	D	E	V	E	E	A	W	K	W	V	D	S	I	T	E	A	W	A	M	D	N	D	A	P	K	P	Y	Q	A	G	T	W	G	P	V	A	S	V	A	M	I
Secondary structure
SS confidence
Disorder																		?																							?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.
Sequence		T	R	D	G	R	S	W	N	E	F	E
Secondary structure
SS confidence
Disorder					?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2bhl chain B Region: 6 - 488 Aligned: 471 Modelled: 480 Confidence: 100.0% Identity: 37% PDB header:oxidoreductase (choh(d)-nadp) Chain: B: PDB Molecule:glucose-6-phosphate 1-dehydrogenase; PDBTitle: x-ray structure of human glucose-6-phosphate dehydrogenase2 (deletion variant) complexed with glucose-6-phosphate Phyre2 PDB 1h9a chain A Region: 6 - 490 Aligned: 475 Modelled: 485 Confidence: 100.0% Identity: 33% PDB header:oxidoreductase (choh(d) - nad(p)) Chain: A: PDB Molecule:glucose 6-phosphate 1-dehydrogenase; PDBTitle: complex of active mutant (q365->c) of glucose 6-phosphate2 dehydrogenase from l. mesenteroides with coenzyme nadp Phyre2 PDB 1qki chain E Region: 3 - 489 Aligned: 475 Modelled: 484 Confidence: 100.0% Identity: 36% PDB header:oxidoreductase Chain: E: PDB Molecule:glucose-6-phosphate 1-dehydrogenase; PDBTitle: x-ray structure of human glucose 6-phosphate dehydrogenase2 (variant canton r459l) complexed with structural nadp+ Phyre2 PDB 1qki chain A domain 2 Region: 176 - 489 Aligned: 290 Modelled: 307 Confidence: 100.0% Identity: 41% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 1h9a chain A domain 2 Region: 181 - 490 Aligned: 289 Modelled: 295 Confidence: 100.0% Identity: 34% Fold: FwdE/GAPDH domain-like Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family: Glucose 6-phosphate dehydrogenase-like Phyre2 PDB 1h9a chain A domain 1 Region: 6 - 194 Aligned: 186 Modelled: 189 Confidence: 100.0% Identity: 30% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 1qki chain A domain 1 Region: 5 - 189 Aligned: 180 Modelled: 185 Confidence: 100.0% Identity: 27% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3m2t chain A Region: 8 - 455 Aligned: 321 Modelled: 346 Confidence: 97.8% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum Phyre2 PDB 3btu chain D Region: 8 - 257 Aligned: 200 Modelled: 218 Confidence: 97.8% Identity: 20% PDB header:transcription Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k] Phyre2 PDB 2nvw chain A domain 1 Region: 1 - 165 Aligned: 130 Modelled: 141 Confidence: 97.7% Identity: 13% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3kux chain A Region: 3 - 467 Aligned: 345 Modelled: 383 Confidence: 97.6% Identity: 17% PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis Phyre2 PDB 3e18 chain A Region: 9 - 461 Aligned: 341 Modelled: 363 Confidence: 97.6% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua Phyre2 PDB 3ezy chain B Region: 11 - 461 Aligned: 322 Modelled: 362 Confidence: 97.4% Identity: 13% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima Phyre2 PDB 3db2 chain C Region: 8 - 166 Aligned: 113 Modelled: 128 Confidence: 97.4% Identity: 19% PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution Phyre2 PDB 1zh8 chain B Region: 9 - 166 Aligned: 115 Modelled: 135 Confidence: 97.3% Identity: 24% PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution Phyre2 PDB 3gfg chain B Region: 5 - 166 Aligned: 115 Modelled: 131 Confidence: 97.3% Identity: 20% PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa; PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form Phyre2 PDB 1h6d chain A domain 1 Region: 1 - 166 Aligned: 126 Modelled: 142 Confidence: 97.3% Identity: 21% Fold: NAD(P)-binding Rossmann-fold domains Superfamily: NAD(P)-binding Rossmann-fold domains Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain Phyre2 PDB 3euw chain B Region: 9 - 166 Aligned: 112 Modelled: 135 Confidence: 97.3% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 Phyre2 PDB 1evj chain C Region: 9 - 468 Aligned: 321 Modelled: 334 Confidence: 97.2% Identity: 18% PDB header:oxidoreductase Chain: C: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d Phyre2 PDB 2nvw chain B Region: 2 - 166 Aligned: 130 Modelled: 142 Confidence: 97.1% Identity: 14% PDB header:transcription Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis Phyre2 1 c2bhlB_ 2 c1h9aA_ 3 c1qkiE_ 4 d1qkia2 5 d1h9aa2 6 d1h9aa1 7 d1qkia1 8 c3m2tA_ 9 c3btuD_ 10 d2nvwa1 11 c3kuxA_ 12 c3e18A_ 13 c3ezyB_ 14 c3db2C_ 15 c1zh8B_ 16 c3gfgB_ 17 d1h6da1 18 c3euwB_ 19 c1evjC_ 20 c2nvwB_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2bhlB_ 100.0 37 PDB header:oxidoreductase (choh(d)-nadp) Chain: B: PDB Molecule:glucose-6-phosphate 1-dehydrogenase; PDBTitle: x-ray structure of human glucose-6-phosphate dehydrogenase2 (deletion variant) complexed with glucose-6-phosphate 2 c1h9aA_ 100.0 33 PDB header:oxidoreductase (choh(d) - nad(p)) Chain: A: PDB Molecule:glucose 6-phosphate 1-dehydrogenase; PDBTitle: complex of active mutant (q365->c) of glucose 6-phosphate2 dehydrogenase from l. mesenteroides with coenzyme nadp 3 c1qkiE_ 100.0 36 PDB header:oxidoreductase Chain: E: PDB Molecule:glucose-6-phosphate 1-dehydrogenase; PDBTitle: x-ray structure of human glucose 6-phosphate dehydrogenase2 (variant canton r459l) complexed with structural nadp+ 4 d1qkia2 100.0 41 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:Glucose 6-phosphate dehydrogenase-like 5 d1h9aa2 100.0 34 Fold:FwdE/GAPDH domain-like Superfamily:Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Family:Glucose 6-phosphate dehydrogenase-like 6 d1h9aa1 100.0 30 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 7 d1qkia1 100.0 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 8 c3m2tA_ 97.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from chromobacterium2 violaceum 9 c3btuD_ 97.8 20 PDB header:transcription Chain: D: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal structure of the super-repressor mutant of gal80p2 from saccharomyces cerevisiae; gal80(s2) [e351k] 10 d2nvwa1 97.7 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 11 c3kuxA_ 97.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the ypo2259 putative oxidoreductase from yersinia pestis 12 c3e18A_ 97.6 18 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of nad-binding protein from listeria innocua 13 c3ezyB_ 97.4 13 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:dehydrogenase; PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima 14 c3db2C_ 97.4 19 PDB header:oxidoreductase Chain: C: PDB Molecule:putative nadph-dependent oxidoreductase; PDBTitle: crystal structure of a putative nadph-dependent oxidoreductase2 (dhaf_2064) from desulfitobacterium hafniense dcb-2 at 1.70 a3 resolution 15 c1zh8B_ 97.3 24 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of oxidoreductase (tm0312) from thermotoga maritima2 at 2.50 a resolution 16 c3gfgB_ 97.3 20 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized oxidoreductase yvaa; PDBTitle: structure of putative oxidoreductase yvaa from bacillus subtilis in2 triclinic form 17 d1h6da1 97.3 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 18 c3euwB_ 97.3 18 PDB header:oxidoreductase Chain: B: PDB Molecule:myo-inositol dehydrogenase; PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032 19 c1evjC_ 97.2 18 PDB header:oxidoreductase Chain: C: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: crystal structure of glucose-fructose oxidoreductase (gfor)2 delta1-22 s64d 20 c2nvwB_ 97.1 14 PDB header:transcription Chain: B: PDB Molecule:galactose/lactose metabolism regulatory protein PDBTitle: crystal sctucture of transcriptional regulator gal80p from2 kluyveromymes lactis 21 c3ec7C_ not modelled 97.0 14 PDB header:oxidoreductase Chain: C: PDB Molecule:putative dehydrogenase; PDBTitle: crystal structure of putative dehydrogenase from salmonella2 typhimurium lt2 22 c3e82A_ not modelled 97.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from2 klebsiella pneumoniae 23 c3uuwB_ not modelled 97.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase with nad(p)-binding rossmann-fold PDBTitle: 1.63 angstrom resolution crystal structure of dehydrogenase (mvim)2 from clostridium difficile. 24 c2glxD_ not modelled 96.9 13 PDB header:oxidoreductase Chain: D: PDB Molecule:1,5-anhydro-d-fructose reductase; PDBTitle: crystal structure analysis of bacterial 1,5-af reductase 25 c3c1aB_ not modelled 96.8 22 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase (zp_00056571.1) from2 magnetospirillum magnetotacticum ms-1 at 1.85 a resolution 26 c3fd8A_ not modelled 96.7 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 27 c1ofgF_ not modelled 96.7 16 PDB header:oxidoreductase Chain: F: PDB Molecule:glucose-fructose oxidoreductase; PDBTitle: glucose-fructose oxidoreductase 28 c1h6dL_ not modelled 96.7 16 PDB header:protein translocation Chain: L: PDB Molecule:precursor form of glucose-fructose PDBTitle: oxidized precursor form of glucose-fructose oxidoreductase2 from zymomonas mobilis complexed with glycerol 29 c3nt5B_ not modelled 96.7 13 PDB header:oxidoreductase Chain: B: PDB Molecule:inositol 2-dehydrogenase/d-chiro-inositol 3-dehydrogenase; PDBTitle: crystal structure of myo-inositol dehydrogenase from bacillus subtilis2 with bound cofactor and product inosose 30 c3f4lF_ not modelled 96.6 16 PDB header:oxidoreductase Chain: F: PDB Molecule:putative oxidoreductase yhhx; PDBTitle: crystal structure of a probable oxidoreductase yhhx in2 triclinic form. northeast structural genomics target er647 31 c3rbvA_ not modelled 96.6 13 PDB header:sugar binding protein Chain: A: PDB Molecule:sugar 3-ketoreductase; PDBTitle: crystal structure of kijd10, a 3-ketoreductase from actinomadura2 kijaniata incomplex with nadp 32 d1zh8a1 not modelled 96.6 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 33 c3e9mC_ not modelled 96.5 17 PDB header:oxidoreductase Chain: C: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from enterococcus2 faecalis 34 c2o48X_ not modelled 96.3 13 PDB header:oxidoreductase Chain: X: PDB Molecule:dimeric dihydrodiol dehydrogenase; PDBTitle: crystal structure of mammalian dimeric dihydrodiol dehydrogenase 35 c3dtyA_ not modelled 96.2 19 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of an oxidoreductase from pseudomonas2 syringae 36 d1ryda1 not modelled 96.2 23 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 37 c2ho3D_ not modelled 96.2 19 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of oxidoreductase, gfo/idh/moca family from2 streptococcus pneumoniae 38 c3ceaA_ not modelled 96.2 13 PDB header:oxidoreductase Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase; PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution 39 c2q4eB_ not modelled 95.8 20 PDB header:oxidoreductase Chain: B: PDB Molecule:probable oxidoreductase at4g09670; PDBTitle: ensemble refinement of the protein crystal structure of gene product2 from arabidopsis thaliana at4g09670 40 c3moiA_ not modelled 95.6 17 PDB header:oxidoreductase Chain: A: PDB Molecule:probable dehydrogenase; PDBTitle: the crystal structure of the putative dehydrogenase from bordetella2 bronchiseptica rb50 41 d1ydwa1 not modelled 95.1 20 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 42 c3oa0B_ not modelled 94.9 16 PDB header:oxidoreductase Chain: B: PDB Molecule:lipopolysaccaride biosynthesis protein wbpb; PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from thermus2 thermophilus in complex with nad and udp-glcnaca 43 c3oqbF_ not modelled 94.8 20 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase from bradyrhizobium2 japonicum usda 110 44 c3fhlC_ not modelled 94.6 19 PDB header:oxidoreductase Chain: C: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of a putative oxidoreductase from bacteroides2 fragilis nctc 9343 45 c1lc3A_ not modelled 94.4 22 PDB header:oxidoreductase Chain: A: PDB Molecule:biliverdin reductase a; PDBTitle: crystal structure of a biliverdin reductase enzyme-cofactor2 complex 46 c1xeaD_ not modelled 94.0 10 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of a gfo/idh/moca family oxidoreductase2 from vibrio cholerae 47 c3q2kB_ not modelled 94.0 15 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase; PDBTitle: crystal structure of the wlba dehydrogenase from bordetella pertussis2 in complex with nadh and udp-glcnaca 48 c1tltB_ not modelled 93.6 15 PDB header:oxidoreductase Chain: B: PDB Molecule:putative oxidoreductase (virulence factor mvim homolog); PDBTitle: crystal structure of a putative oxidoreductase (virulence factor mvim2 homolog) 49 c3oa2B_ not modelled 93.6 17 PDB header:oxidoreductase Chain: B: PDB Molecule:wbpb; PDBTitle: crystal structure of the wlba (wbpb) dehydrogenase from pseudomonas2 aeruginosa in complex with nad at 1.5 angstrom resolution 50 c3ip3D_ not modelled 93.6 14 PDB header:oxidoreductase Chain: D: PDB Molecule:oxidoreductase, putative; PDBTitle: structure of putative oxidoreductase (tm_0425) from2 thermotoga maritima 51 d1tlta1 not modelled 93.4 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 52 d1xeaa1 not modelled 93.4 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 53 c2ixaA_ not modelled 93.0 18 PDB header:hydrolase Chain: A: PDB Molecule:alpha-n-acetylgalactosaminidase; PDBTitle: a-zyme, n-acetylgalactosaminidase 54 d1lc0a1 not modelled 92.4 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 55 c3evnA_ not modelled 91.5 14 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, gfo/idh/moca family; PDBTitle: crystal structure of putative oxidoreductase from streptococcus2 agalactiae 2603v/r 56 d1oi7a1 not modelled 90.2 6 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 57 c3v5nA_ not modelled 89.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase; PDBTitle: the crystal structure of oxidoreductase from sinorhizobium meliloti 58 c2zcuA_ not modelled 89.4 21 PDB header:oxidoreductase Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg; PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli 59 d1xgka_ not modelled 86.9 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 60 c2vrcD_ not modelled 86.3 18 PDB header:oxidoreductase Chain: D: PDB Molecule:triphenylmethane reductase; PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h) 61 c2c20D_ not modelled 81.5 24 PDB header:isomerase Chain: D: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: crystal structure of udp-glucose 4-epimerase 62 d2nu7a1 not modelled 79.5 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 63 c2v6gA_ not modelled 79.0 19 PDB header:oxidoreductase Chain: A: PDB Molecule:progesterone 5-beta-reductase; PDBTitle: structure of progesterone 5beta-reductase from digitalis2 lanata in complex with nadp 64 d1wvga1 not modelled 77.0 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 65 c2gn9B_ not modelled 74.5 20 PDB header:lyase Chain: B: PDB Molecule:udp-glcnac c6 dehydratase; PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc 66 c1t2aC_ not modelled 73.5 17 PDB header:structural genomics,lyase Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase; PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase 67 d1t2aa_ not modelled 73.5 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 68 c2z1mC_ not modelled 68.0 17 PDB header:lyase Chain: C: PDB Molecule:gdp-d-mannose dehydratase; PDBTitle: crystal structure of gdp-d-mannose dehydratase from aquifex aeolicus2 vf5 69 d1db3a_ not modelled 67.0 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 70 d1x1na1 not modelled 65.2 25 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 71 d1z45a2 not modelled 64.6 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 72 d1tz7a1 not modelled 63.5 25 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 73 d1eswa_ not modelled 61.0 30 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:Amylase, catalytic domain 74 d1rkxa_ not modelled 60.7 11 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 75 d1udca_ not modelled 59.9 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 76 c2qx7A_ not modelled 57.5 16 PDB header:plant protein Chain: A: PDB Molecule:eugenol synthase 1; PDBTitle: structure of eugenol synthase from ocimum basilicum 77 d2q46a1 not modelled 55.9 16 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 78 c2iodD_ not modelled 55.4 16 PDB header:oxidoreductase Chain: D: PDB Molecule:dihydroflavonol 4-reductase; PDBTitle: binding of two substrate analogue molecules to2 dihydroflavonol-4-reductase alters the functional geometry3 of the catalytic site 79 c3enkB_ not modelled 54.8 17 PDB header:isomerase Chain: B: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei 80 c2p5uC_ not modelled 53.7 13 PDB header:isomerase Chain: C: PDB Molecule:udp-glucose 4-epimerase; PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad 81 c3e48B_ not modelled 53.2 16 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase; PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319 82 c3mjsA_ not modelled 52.9 19 PDB header:oxidoreductase Chain: A: PDB Molecule:amphb; PDBTitle: structure of a-type ketoreductases from modular polyketide synthase 83 c2pk3B_ not modelled 52.2 25 PDB header:oxidoreductase Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase; PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase 84 c3slgB_ not modelled 51.6 19 PDB header:transferase Chain: B: PDB Molecule:pbgp3 protein; PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei 85 d1i24a_ not modelled 51.5 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 86 d2blla1 not modelled 50.2 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 87 d1n7ha_ not modelled 48.2 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 88 c2q1wC_ not modelled 47.6 23 PDB header:sugar binding protein Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+ 89 d1euca1 not modelled 47.3 15 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 90 c3qvoA_ not modelled 46.6 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:nmra family protein; PDBTitle: structure of a rossmann-fold nad(p)-binding family protein from2 shigella flexneri. 91 c2p2sA_ not modelled 44.6 16 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: crystal structure of putative oxidoreductase (yp_050235.1) from2 erwinia carotovora atroseptica scri1043 at 1.25 a resolution 92 c3r6dA_ not modelled 43.9 17 PDB header:lyase, isomerase Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of nad-dependent epimerase/dehydratase from2 veillonella parvula dsm 2008 with cz-methylated lysine 93 d1bxka_ not modelled 43.8 19 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 94 d1orra_ not modelled 42.9 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 95 c1e5lA_ not modelled 41.3 25 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine reductase; PDBTitle: apo saccharopine reductase from magnaporthe grisea 96 c3h2sA_ not modelled 40.3 16 PDB header:oxidoreductase Chain: A: PDB Molecule:putative nadh-flavin reductase; PDBTitle: crystal structure of the q03b84 protein from lactobacillus2 casei. northeast structural genomics consortium target3 lcr19. 97 c3ay3C_ not modelled 38.3 22 PDB header:oxidoreductase Chain: C: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of glucuronic acid dehydrogeanse from2 chromohalobacter salexigens 98 d1gy8a_ not modelled 35.1 9 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 99 c2p4hX_ not modelled 35.1 30 PDB header:plant protein Chain: X: PDB Molecule:vestitone reductase; PDBTitle: crystal structure of vestitone reductase from alfalfa2 (medicago sativa l.) 100 c1j5pA_ not modelled 34.8 6 PDB header:oxidoreductase Chain: A: PDB Molecule:aspartate dehydrogenase; PDBTitle: crystal structure of aspartate dehydrogenase (tm1643) from thermotoga2 maritima at 1.9 a resolution 101 c2axqA_ not modelled 34.8 23 PDB header:oxidoreductase Chain: A: PDB Molecule:saccharopine dehydrogenase; PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae 102 d1vl0a_ not modelled 34.2 27 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 103 c3dqpA_ not modelled 32.5 34 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase ylbe; PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121. 104 c3dhnA_ not modelled 32.4 33 PDB header:isomerase, lyase Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase; PDBTitle: crystal structure of the putative epimerase q89z24_bactn2 from bacteroides thetaiotaomicron. northeast structural3 genomics consortium target btr310. 105 c2ggsB_ not modelled 32.3 25 PDB header:oxidoreductase Chain: B: PDB Molecule:273aa long hypothetical dtdp-4-dehydrorhamnose PDBTitle: crystal structure of hypothetical dtdp-4-dehydrorhamnose2 reductase from sulfolobus tokodaii 106 c3ew7A_ not modelled 31.8 28 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo0794 protein; PDBTitle: crystal structure of the lmo0794 protein from listeria2 monocytogenes. northeast structural genomics consortium3 target lmr162. 107 c1z7eC_ not modelled 31.3 11 PDB header:hydrolase Chain: C: PDB Molecule:protein arna; PDBTitle: crystal structure of full length arna 108 c2pzlB_ not modelled 30.8 16 PDB header:sugar binding protein Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase; PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp 109 c3th6B_ not modelled 30.5 20 PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase from rhipicephalus2 (boophilus) microplus. 110 d1n2sa_ not modelled 30.3 25 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 111 d1ebfa1 not modelled 29.7 18 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 112 d1rpna_ not modelled 29.5 21 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 113 c3rfxB_ not modelled 29.2 19 PDB header:oxidoreductase Chain: B: PDB Molecule:uronate dehydrogenase; PDBTitle: crystal structure of uronate dehydrogenase from agrobacterium2 tumefaciens, y136a mutant complexed with nad 114 c3sc6F_ not modelled 27.8 30 PDB header:oxidoreductase Chain: F: PDB Molecule:dtdp-4-dehydrorhamnose reductase; PDBTitle: 2.65 angstrom resolution crystal structure of dtdp-4-dehydrorhamnose2 reductase (rfbd) from bacillus anthracis str. ames in complex with3 nadp 115 d1nnxa_ not modelled 27.5 60 Fold:OB-fold Superfamily:Hypothetical protein YgiW Family:Hypothetical protein YgiW 116 c2vz8B_ not modelled 27.4 23 PDB header:transferase Chain: B: PDB Molecule:fatty acid synthase; PDBTitle: crystal structure of mammalian fatty acid synthase 117 c1n7gB_ not modelled 27.1 19 PDB header:lyase Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase; PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose. 118 d1ek6a_ not modelled 27.1 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 119 c2ysrA_ not modelled 26.6 24 PDB header:signaling protein Chain: A: PDB Molecule:dep domain-containing protein 1; PDBTitle: solution structure of the dep domain from human dep domain-2 containing protein 1 120 c3kxqB_ not modelled 26.2 17 PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: crystal structure of triosephosphate isomerase from bartonella2 henselae at 1.6a resolution

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0