Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	T	L	I	A	R	H	K	A	G	E	H	I	G	I	C	S	V	C	S	A	H	P	L	V	I	E	A	A	L	A	F	D	R	N	S	T	R	K	V	L	I	E	A	T	S	N	Q	V	N	Q	F	G	G	Y	T	G	M	T
Secondary structure
SS confidence
Disorder		?	?																																		?		?													?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		P	A	D	F	R	E	F	V	F	T	I	A	D	K	V	G	F	A	R	E	R	I	I	L	G	G	D	H	L	G	P	N	C	W	Q	Q	E	N	A	D	A	A	M	E	K	S	V	E	L	V	K	E	Y	V	R	A	G	F	S	K
Secondary structure
SS confidence
Disorder																																				?		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		I	H	L	D	A	S	M	S	C	A	G	D	P	I	P	L	A	P	E	T	V	A	E	R	A	A	V	L	C	F	A	A	E	S	V	A	T	D	C	Q	R	E	Q	L	S	Y	V	I	G	T	E	V	P	V	P	G	G	E	A	S
Secondary structure
SS confidence
Disorder												?																												?	?														?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		A	I	Q	S	V	H	I	T	H	V	E	D	A	A	N	T	L	R	T	H	Q	K	A	F	I	A	R	G	L	T	E	A	L	T	R	V	I	A	I	V	V	Q	P	G	V	E	F	D	H	S	N	I	I	H	Y	Q	P	Q	E	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		Q	P	L	A	Q	W	I	E	N	T	R	M	V	Y	E	A	H	S	T	D	Y	Q	T	R	T	A	Y	W	E	L	V	R	D	H	F	A	I	L	K	V	G	P	A	L	T	F	A	L	R	E	A	I	F	A	L	A	Q	I	E	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		E	L	I	A	P	E	N	R	S	G	C	L	A	V	I	E	E	V	M	L	D	E	P	Q	Y	W	K	K	Y	Y	R	T	G	F	N	D	S	L	L	D	I	R	Y	S	L	S	D	R	I	R	Y	Y	W	P	H	S	R	I	K	N
Secondary structure
SS confidence
Disorder																						?		?								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		S	V	E	T	M	M	V	N	L	E	G	V	D	I	P	L	G	M	I	S	Q	Y	L	P	K	Q	F	E	R	I	Q	S	G	E	L	S	A	I	P	H	Q	L	I	M	D	K	I	Y	D	V	L	R	A	Y	R	Y	G	C	A	E
Secondary structure
SS confidence
Disorder																																	?	?	?																								?	?	?
Disorder confidence
Sequence
Secondary structure
SS confidence
Disorder
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2fiq chain A domain 1 Region: 1 - 420 Aligned: 410 Modelled: 419 Confidence: 100.0% Identity: 96% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: GatZ-like Phyre2 PDB 3q94 chain B Region: 1 - 331 Aligned: 263 Modelled: 276 Confidence: 99.9% Identity: 15% PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' Phyre2 PDB 1rvg chain A Region: 1 - 331 Aligned: 263 Modelled: 291 Confidence: 99.9% Identity: 17% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 1dos chain A Region: 1 - 295 Aligned: 260 Modelled: 273 Confidence: 99.9% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 1gvf chain A Region: 1 - 331 Aligned: 259 Modelled: 279 Confidence: 99.9% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Aldolase Family: Class II FBP aldolase Phyre2 PDB 3c52 chain B Region: 1 - 331 Aligned: 258 Modelled: 278 Confidence: 99.9% Identity: 15% PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor Phyre2 PDB 3elf chain A Region: 3 - 338 Aligned: 295 Modelled: 317 Confidence: 99.9% Identity: 15% PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase Phyre2 PDB 3qm3 chain C Region: 1 - 295 Aligned: 257 Modelled: 280 Confidence: 99.9% Identity: 17% PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni Phyre2 PDB 2isw chain B Region: 1 - 331 Aligned: 243 Modelled: 272 Confidence: 99.9% Identity: 17% PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate Phyre2 PDB 3pm6 chain B Region: 2 - 339 Aligned: 249 Modelled: 277 Confidence: 99.9% Identity: 16% PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr Phyre2 PDB 1f6y chain A Region: 1 - 133 Aligned: 111 Modelled: 120 Confidence: 95.8% Identity: 21% Fold: TIM beta/alpha-barrel Superfamily: Dihydropteroate synthetase-like Family: Methyltetrahydrofolate-utiluzing methyltransferases Phyre2 PDB 3bol chain B Region: 1 - 133 Aligned: 110 Modelled: 120 Confidence: 95.8% Identity: 16% PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ Phyre2 PDB 3bof chain A domain 1 Region: 1 - 133 Aligned: 110 Modelled: 120 Confidence: 95.4% Identity: 16% Fold: TIM beta/alpha-barrel Superfamily: Dihydropteroate synthetase-like Family: Methyltetrahydrofolate-utiluzing methyltransferases Phyre2 PDB 1rr2 chain A Region: 1 - 216 Aligned: 172 Modelled: 183 Confidence: 94.8% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid Phyre2 PDB 1mum chain A Region: 30 - 344 Aligned: 253 Modelled: 298 Confidence: 93.7% Identity: 15% Fold: TIM beta/alpha-barrel Superfamily: Phosphoenolpyruvate/pyruvate domain Family: Phosphoenolpyruvate mutase/Isocitrate lyase-like Phyre2 PDB 2h9a chain A Region: 17 - 132 Aligned: 82 Modelled: 101 Confidence: 93.1% Identity: 22% PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein Phyre2 PDB 2yci chain X Region: 17 - 170 Aligned: 124 Modelled: 139 Confidence: 91.9% Identity: 20% PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native Phyre2 PDB 3k13 chain A Region: 17 - 180 Aligned: 126 Modelled: 141 Confidence: 91.4% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron Phyre2 PDB 2dza chain A Region: 17 - 162 Aligned: 115 Modelled: 131 Confidence: 91.2% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate Phyre2 PDB 2nx9 chain B Region: 1 - 216 Aligned: 172 Modelled: 182 Confidence: 90.8% Identity: 15% PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae Phyre2 1 d2fiqa1 2 c3q94B_ 3 d1rvga_ 4 d1dosa_ 5 d1gvfa_ 6 c3c52B_ 7 c3elfA_ 8 c3qm3C_ 9 c2iswB_ 10 c3pm6B_ 11 d1f6ya_ 12 c3bolB_ 13 d3bofa1 14 c1rr2A_ 15 d1muma_ 16 c2h9aA_ 17 c2yciX_ 18 c3k13A_ 19 c2dzaA_ 20 c2nx9B_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2fiqa1 100.0 96 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:GatZ-like 2 c3q94B_ 99.9 15 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase, class ii; PDBTitle: the crystal structure of fructose 1,6-bisphosphate aldolase from2 bacillus anthracis str. 'ames ancestor' 3 d1rvga_ 99.9 17 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 4 d1dosa_ 99.9 15 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 5 d1gvfa_ 99.9 16 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:Class II FBP aldolase 6 c3c52B_ 99.9 15 PDB header:lyase Chain: B: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: class ii fructose-1,6-bisphosphate aldolase from2 helicobacter pylori in complex with3 phosphoglycolohydroxamic acid, a competitive inhibitor 7 c3elfA_ 99.9 15 PDB header:lyase Chain: A: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: structural characterization of tetrameric mycobacterium tuberculosis2 fructose 1,6-bisphosphate aldolase - substrate binding and catalysis3 mechanism of a class iia bacterial aldolase 8 c3qm3C_ 99.9 17 PDB header:lyase Chain: C: PDB Molecule:fructose-bisphosphate aldolase; PDBTitle: 1.85 angstrom resolution crystal structure of fructose-bisphosphate2 aldolase (fba) from campylobacter jejuni 9 c2iswB_ 99.9 17 PDB header:lyase Chain: B: PDB Molecule:putative fructose-1,6-bisphosphate aldolase; PDBTitle: structure of giardia fructose-1,6-biphosphate aldolase in2 complex with phosphoglycolohydroxamate 10 c3pm6B_ 99.9 16 PDB header:lyase Chain: B: PDB Molecule:putative fructose-bisphosphate aldolase; PDBTitle: crystal structure of a putative fructose-1,6-biphosphate aldolase from2 coccidioides immitis solved by combined sad mr 11 d1f6ya_ 95.8 21 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 12 c3bolB_ 95.8 16 PDB header:transferase Chain: B: PDB Molecule:5-methyltetrahydrofolate s-homocysteine PDBTitle: cobalamin-dependent methionine synthase (1-566) from2 thermotoga maritima complexed with zn2+ 13 d3bofa1 95.4 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Methyltetrahydrofolate-utiluzing methyltransferases 14 c1rr2A_ 94.8 13 PDB header:transferase Chain: A: PDB Molecule:transcarboxylase 5s subunit; PDBTitle: propionibacterium shermanii transcarboxylase 5s subunit bound to 2-2 ketobutyric acid 15 d1muma_ 93.7 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 16 c2h9aA_ 93.1 22 PDB header:oxidoreductase Chain: A: PDB Molecule:carbon monoxide dehydrogenase corrinoid/iron- PDBTitle: corrinoid iron-sulfur protein 17 c2yciX_ 91.9 20 PDB header:transferase Chain: X: PDB Molecule:5-methyltetrahydrofolate corrinoid/iron sulfur protein PDBTitle: methyltransferase native 18 c3k13A_ 91.4 21 PDB header:transferase Chain: A: PDB Molecule:5-methyltetrahydrofolate-homocysteine methyltransferase; PDBTitle: structure of the pterin-binding domain metr of 5-2 methyltetrahydrofolate-homocysteine methyltransferase from3 bacteroides thetaiotaomicron 19 c2dzaA_ 91.2 21 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of dihydropteroate synthase from thermus2 thermophilus hb8 in complex with 4-aminobenzoate 20 c2nx9B_ 90.8 15 PDB header:lyase Chain: B: PDB Molecule:oxaloacetate decarboxylase 2, subunit alpha; PDBTitle: crystal structure of the carboxyltransferase domain of the2 oxaloacetate decarboxylase na+ pump from vibrio cholerae 21 c2vp8A_ not modelled 90.1 18 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase 2; PDBTitle: structure of mycobacterium tuberculosis rv1207 22 c2ze3A_ not modelled 89.5 17 PDB header:isomerase Chain: A: PDB Molecule:dfa0005; PDBTitle: crystal structure of dfa0005 complexed with alpha-ketoglutarate: a2 novel member of the icl/pepm superfamily from alkali-tolerant3 deinococcus ficus 23 c2qiwA_ not modelled 88.6 14 PDB header:transferase Chain: A: PDB Molecule:pep phosphonomutase; PDBTitle: crystal structure of a putative phosphoenolpyruvate phosphonomutase2 (ncgl1015, cgl1060) from corynebacterium glutamicum atcc 13032 at3 1.80 a resolution 24 c1ps9A_ not modelled 86.8 14 PDB header:oxidoreductase Chain: A: PDB Molecule:2,4-dienoyl-coa reductase; PDBTitle: the crystal structure and reaction mechanism of e. coli 2,4-2 dienoyl coa reductase 25 d1tx2a_ not modelled 84.5 17 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 26 c1tx2A_ not modelled 84.5 17 PDB header:transferase Chain: A: PDB Molecule:dhps, dihydropteroate synthase; PDBTitle: dihydropteroate synthetase, with bound inhibitor manic, from bacillus2 anthracis 27 c3hf3A_ not modelled 83.2 21 PDB header:oxidoreductase Chain: A: PDB Molecule:chromate reductase; PDBTitle: old yellow enzyme from thermus scotoductus sa-01 28 c3b8iF_ not modelled 83.0 18 PDB header:lyase Chain: F: PDB Molecule:pa4872 oxaloacetate decarboxylase; PDBTitle: crystal structure of oxaloacetate decarboxylase from pseudomonas2 aeruginosa (pa4872) in complex with oxalate and mg2+. 29 c3cqkB_ not modelled 83.0 9 PDB header:isomerase Chain: B: PDB Molecule:l-ribulose-5-phosphate 3-epimerase ulae; PDBTitle: crystal structure of l-xylulose-5-phosphate 3-epimerase ulae (form b)2 complex with zn2+ and sulfate 30 d1eyea_ not modelled 82.4 16 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 31 d1vhna_ not modelled 80.8 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 32 d1ps9a1 not modelled 79.7 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 33 d1ad1a_ not modelled 77.9 20 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 34 c3lhlA_ not modelled 77.2 17 PDB header:hydrolase Chain: A: PDB Molecule:putative agmatinase; PDBTitle: crystal structure of a putative agmatinase from clostridium difficile 35 d1z41a1 not modelled 75.2 19 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 36 c3k2gA_ not modelled 75.1 13 PDB header:resiniferatoxin binding protein Chain: A: PDB Molecule:resiniferatoxin-binding, phosphotriesterase- PDBTitle: crystal structure of a resiniferatoxin-binding protein from2 rhodobacter sphaeroides 37 d1vyra_ not modelled 72.1 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 38 d1ajza_ not modelled 71.9 19 Fold:TIM beta/alpha-barrel Superfamily:Dihydropteroate synthetase-like Family:Dihydropteroate synthetase 39 c3d0kA_ not modelled 71.5 15 PDB header:hydrolase Chain: A: PDB Molecule:putative poly(3-hydroxybutyrate) depolymerase lpqc; PDBTitle: crystal structure of the lpqc, poly(3-hydroxybutyrate) depolymerase2 from bordetella parapertussis 40 c1vraB_ not modelled 69.9 23 PDB header:transferase Chain: B: PDB Molecule:arginine biosynthesis bifunctional protein argj; PDBTitle: crystal structure of arginine biosynthesis bifunctional protein argj2 (10175521) from bacillus halodurans at 2.00 a resolution 41 c2y5sA_ not modelled 68.3 14 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: crystal structure of burkholderia cenocepacia dihydropteroate2 synthase complexed with 7,8-dihydropteroate. 42 c3inpA_ not modelled 68.2 14 PDB header:isomerase Chain: A: PDB Molecule:d-ribulose-phosphate 3-epimerase; PDBTitle: 2.05 angstrom resolution crystal structure of d-ribulose-phosphate 3-2 epimerase from francisella tularensis. 43 d1gq6a_ not modelled 67.8 19 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 44 c3it4B_ not modelled 67.2 19 PDB header:transferase Chain: B: PDB Molecule:arginine biosynthesis bifunctional protein argj PDBTitle: the crystal structure of ornithine acetyltransferase from2 mycobacterium tuberculosis (rv1653) at 1.7 a 45 c3l5aA_ not modelled 67.2 11 PDB header:oxidoreductase Chain: A: PDB Molecule:nadh/flavin oxidoreductase/nadh oxidase; PDBTitle: crystal structure of a probable nadh-dependent flavin oxidoreductase2 from staphylococcus aureus 46 c3nioF_ not modelled 66.9 19 PDB header:hydrolase Chain: F: PDB Molecule:guanidinobutyrase; PDBTitle: crystal structure of pseudomonas aeruginosa guanidinobutyrase 47 c2gq8A_ not modelled 65.0 14 PDB header:oxidoreductase Chain: A: PDB Molecule:oxidoreductase, fmn-binding; PDBTitle: structure of sye1, an oye homologue from s. ondeidensis, in complex2 with p-hydroxyacetophenone 48 d1pq3a_ not modelled 63.7 19 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 49 d1xfka_ not modelled 63.6 18 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 50 d2a0ma1 not modelled 62.6 26 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 51 d2ceva_ not modelled 61.4 18 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 52 d2glka1 not modelled 59.4 14 Fold:TIM beta/alpha-barrel Superfamily:Xylose isomerase-like Family:Xylose isomerase 53 c3atyA_ not modelled 57.3 19 PDB header:oxidoreductase Chain: A: PDB Molecule:prostaglandin f2a synthase; PDBTitle: crystal structure of tcoye 54 d2ihta3 not modelled 55.5 27 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 55 c3r4iB_ not modelled 55.2 6 PDB header:lyase Chain: B: PDB Molecule:citrate lyase; PDBTitle: crystal structure of a citrate lyase (bxe_b2899) from burkholderia2 xenovorans lb400 at 2.24 a resolution 56 d1woha_ not modelled 54.4 21 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 57 c1cqxB_ not modelled 50.3 25 PDB header:lipid binding protein Chain: B: PDB Molecule:flavohemoprotein; PDBTitle: crystal structure of the flavohemoglobin from alcaligenes eutrophus at2 1.75 a resolution 58 d1ujqa_ not modelled 49.5 17 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Phosphoenolpyruvate mutase/Isocitrate lyase-like 59 d1t4ba1 not modelled 48.6 14 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 60 d2csua1 not modelled 47.9 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:CoA-binding domain 61 c3nipB_ not modelled 47.9 16 PDB header:hydrolase Chain: B: PDB Molecule:3-guanidinopropionase; PDBTitle: crystal structure of pseudomonas aeruginosa guanidinopropionase2 complexed with 1,6-diaminohexane 62 d1qi9a_ not modelled 47.3 17 Fold:Acid phosphatase/Vanadium-dependent haloperoxidase Superfamily:Acid phosphatase/Vanadium-dependent haloperoxidase Family:Haloperoxidase (bromoperoxidase) 63 d1gwja_ not modelled 46.9 17 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 64 d1m6ja_ not modelled 46.4 19 Fold:TIM beta/alpha-barrel Superfamily:Triosephosphate isomerase (TIM) Family:Triosephosphate isomerase (TIM) 65 c3qxbB_ not modelled 46.1 8 PDB header:isomerase Chain: B: PDB Molecule:putative xylose isomerase; PDBTitle: crystal structure of a putative xylose isomerase (yp_426450.1) from2 rhodospirillum rubrum atcc 11170 at 1.90 a resolution 66 d1yl7a1 not modelled 45.7 26 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain 67 d1icpa_ not modelled 45.3 15 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 68 d1h6za1 not modelled 43.9 18 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Pyruvate phosphate dikinase, C-terminal domain 69 d1t9ba3 not modelled 43.4 21 Fold:Thiamin diphosphate-binding fold (THDP-binding) Superfamily:Thiamin diphosphate-binding fold (THDP-binding) Family:Pyruvate oxidase and decarboxylase PP module 70 c2h9aB_ not modelled 43.3 15 PDB header:oxidoreductase Chain: B: PDB Molecule:co dehydrogenase/acetyl-coa synthase, iron- PDBTitle: corrinoid iron-sulfur protein 71 c3gr7A_ not modelled 43.3 15 PDB header:oxidoreductase Chain: A: PDB Molecule:nadph dehydrogenase; PDBTitle: structure of oye from geobacillus kaustophilus, hexagonal2 crystal form 72 d1vz6a_ not modelled 42.5 20 Fold:DmpA/ArgJ-like Superfamily:DmpA/ArgJ-like Family:ArgJ-like 73 d1oyaa_ not modelled 41.9 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 74 c2o1tB_ not modelled 41.6 12 PDB header:chaperone Chain: B: PDB Molecule:endoplasmin; PDBTitle: structure of middle plus c-terminal domains (m+c) of grp94 75 c2vzkD_ not modelled 41.3 19 PDB header:transferase Chain: D: PDB Molecule:glutamate n-acetyltransferase 2 beta chain; PDBTitle: structure of the acyl-enzyme complex of an n-terminal2 nucleophile (ntn) hydrolase, oat2 76 c2qw5B_ not modelled 40.0 9 PDB header:isomerase Chain: B: PDB Molecule:xylose isomerase-like tim barrel; PDBTitle: crystal structure of a putative sugar phosphate isomerase/epimerase2 (ava4194) from anabaena variabilis atcc 29413 at 1.78 a resolution 77 c3m1rF_ not modelled 39.8 32 PDB header:hydrolase Chain: F: PDB Molecule:formimidoylglutamase; PDBTitle: the crystal structure of formimidoylglutamase from bacillus2 subtilis subsp. subtilis str. 168 78 c3no4A_ not modelled 39.3 16 PDB header:hydrolase Chain: A: PDB Molecule:creatinine amidohydrolase; PDBTitle: crystal structure of a creatinine amidohydrolase (npun_f1913) from2 nostoc punctiforme pcc 73102 at 2.00 a resolution 79 c3o1lB_ not modelled 39.0 13 PDB header:hydrolase Chain: B: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (pspto_4314)2 from pseudomonas syringae pv. tomato str. dc3000 at 2.20 a resolution 80 c2gq0B_ not modelled 38.1 19 PDB header:chaperone, hydrolase Chain: B: PDB Molecule:chaperone protein htpg; PDBTitle: crystal structure of the middle domain of htpg, the e. coli2 hsp90 81 c1y6zA_ not modelled 36.8 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:heat shock protein, putative; PDBTitle: middle domain of plasmodium falciparum putative heat shock protein2 pf14_0417 82 c3dxiB_ not modelled 36.3 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative aldolase; PDBTitle: crystal structure of the n-terminal domain of a putative2 aldolase (bvu_2661) from bacteroides vulgatus 83 c3tr9A_ not modelled 35.3 15 PDB header:transferase Chain: A: PDB Molecule:dihydropteroate synthase; PDBTitle: structure of a dihydropteroate synthase (folp) in complex with pteroic2 acid from coxiella burnetii 84 c3nrbD_ not modelled 34.0 21 PDB header:hydrolase Chain: D: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (puru,2 pp_1943) from pseudomonas putida kt2440 at 2.05 a resolution 85 c3mmrA_ not modelled 33.6 17 PDB header:hydrolase Chain: A: PDB Molecule:arginase; PDBTitle: structure of plasmodium falciparum arginase in complex with abh 86 c1nofA_ not modelled 33.3 11 PDB header:hydrolase Chain: A: PDB Molecule:xylanase; PDBTitle: the first crystallographic structure of a xylanase from2 glycosyl hydrolase family 5: implications for catalysis 87 c3icgD_ not modelled 33.3 16 PDB header:hydrolase Chain: D: PDB Molecule:endoglucanase d; PDBTitle: crystal structure of the catalytic and carbohydrate binding domain of2 endoglucanase d from clostridium cellulovorans 88 c3pzlA_ not modelled 32.5 19 PDB header:hydrolase Chain: A: PDB Molecule:agmatine ureohydrolase; PDBTitle: the crystal structure of agmatine ureohydrolase of thermoplasma2 volcanium 89 c3obiC_ not modelled 31.9 14 PDB header:hydrolase Chain: C: PDB Molecule:formyltetrahydrofolate deformylase; PDBTitle: crystal structure of a formyltetrahydrofolate deformylase (np_949368)2 from rhodopseudomonas palustris cga009 at 1.95 a resolution 90 d1vjia_ not modelled 31.9 13 Fold:TIM beta/alpha-barrel Superfamily:FMN-linked oxidoreductases Family:FMN-linked oxidoreductases 91 d2aeba1 not modelled 31.7 19 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 92 d1luaa2 not modelled 31.1 22 Fold:Aminoacid dehydrogenase-like, N-terminal domain Superfamily:Aminoacid dehydrogenase-like, N-terminal domain Family:Methylene-tetrahydromethanopterin dehydrogenase 93 c3i05B_ not modelled 30.4 19 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from trypanosoma brucei 94 c2cgeD_ not modelled 30.3 14 PDB header:chaperone Chain: D: PDB Molecule:atp-dependent molecular chaperone hsp82; PDBTitle: crystal structure of an hsp90-sba1 closed chaperone complex 95 c1gqkB_ not modelled 30.2 55 PDB header:hydrolase Chain: B: PDB Molecule:alpha-d-glucuronidase; PDBTitle: structure of pseudomonas cellulosa alpha-d-glucuronidase2 complexed with glucuronic acid 96 c1ydnA_ not modelled 29.9 10 PDB header:lyase Chain: A: PDB Molecule:hydroxymethylglutaryl-coa lyase; PDBTitle: crystal structure of the hmg-coa lyase from brucella melitensis,2 northeast structural genomics target lr35. 97 c1wr2A_ not modelled 29.9 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein ph1789; PDBTitle: crystal structure of ph1788 from pyrococcus horikoshii ot3 98 c3bleA_ not modelled 29.3 18 PDB header:transferase Chain: A: PDB Molecule:citramalate synthase from leptospira interrogans; PDBTitle: crystal structure of the catalytic domain of licms in2 complexed with malonate 99 d1d3va_ not modelled 28.2 18 Fold:Arginase/deacetylase Superfamily:Arginase/deacetylase Family:Arginase-like amidino hydrolases 100 d1oy0a_ not modelled 28.0 22 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Ketopantoate hydroxymethyltransferase PanB 101 d1zs9a1 not modelled 27.8 13 Fold:HAD-like Superfamily:HAD-like Family:Enolase-phosphatase E1 102 c3ih1A_ not modelled 27.7 12 PDB header:lyase Chain: A: PDB Molecule:methylisocitrate lyase; PDBTitle: crystal structure of carboxyvinyl-carboxyphosphonate phosphorylmutase2 from bacillus anthracis 103 c3n2tA_ not modelled 27.4 19 PDB header:oxidoreductase Chain: A: PDB Molecule:putative oxidoreductase; PDBTitle: structure of the glycerol dehydrogenase akr11b4 from gluconobacter2 oxydans 104 c3lyeA_ not modelled 27.2 14 PDB header:hydrolase Chain: A: PDB Molecule:oxaloacetate acetyl hydrolase; PDBTitle: crystal structure of oxaloacetate acetylhydrolase 105 c3epmB_ not modelled 27.1 19 PDB header:biosynthetic protein Chain: B: PDB Molecule:thiamine biosynthesis protein thic; PDBTitle: crystal structure of caulobacter crescentus thic 106 c3q6nF_ not modelled 27.0 17 PDB header:chaperone Chain: F: PDB Molecule:heat shock protein hsp 90-alpha; PDBTitle: crystal structure of human mc-hsp90 in p21 space group 107 d2p02a1 not modelled 26.9 20 Fold:S-adenosylmethionine synthetase Superfamily:S-adenosylmethionine synthetase Family:S-adenosylmethionine synthetase 108 c3opbA_ not modelled 24.9 19 PDB header:protein binding Chain: A: PDB Molecule:swi5-dependent ho expression protein 4; PDBTitle: crystal structure of she4p 109 d2hcfa1 not modelled 24.8 9 Fold:HAD-like Superfamily:HAD-like Family:beta-Phosphoglucomutase-like 110 c3mwdB_ not modelled 24.8 14 PDB header:transferase Chain: B: PDB Molecule:atp-citrate synthase; PDBTitle: truncated human atp-citrate lyase with citrate bound 111 c3krsB_ not modelled 24.8 16 PDB header:isomerase Chain: B: PDB Molecule:triosephosphate isomerase; PDBTitle: structure of triosephosphate isomerase from cryptosporidium parvum at2 1.55a resolution 112 d1r5ja_ not modelled 24.6 14 Fold:Isocitrate/Isopropylmalate dehydrogenase-like Superfamily:Isocitrate/Isopropylmalate dehydrogenase-like Family:Phosphotransacetylase 113 c1vm6B_ not modelled 24.5 9 PDB header:oxidoreductase Chain: B: PDB Molecule:dihydrodipicolinate reductase; PDBTitle: crystal structure of dihydrodipicolinate reductase (tm1520) from2 thermotoga maritima at 2.27 a resolution 114 d1qh8b_ not modelled 24.3 19 Fold:Chelatase-like Superfamily:"Helical backbone" metal receptor Family:Nitrogenase iron-molybdenum protein 115 c3pryA_ not modelled 24.2 14 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein hsp 90-beta; PDBTitle: crystal structure of the middle domain of human hsp90-beta refined at2 2.3 a resolution 116 c3gkaB_ not modelled 23.7 17 PDB header:oxidoreductase Chain: B: PDB Molecule:n-ethylmaleimide reductase; PDBTitle: crystal structure of n-ethylmaleimidine reductase from2 burkholderia pseudomallei 117 d1rqba2 not modelled 23.4 13 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:HMGL-like 118 c3hjcA_ not modelled 23.0 24 PDB header:chaperone Chain: A: PDB Molecule:heat shock protein 83-1; PDBTitle: crystal structure of the carboxy-terminal domain of hsp90 from2 leishmania major, lmjf33.0312 119 c2v1dA_ not modelled 22.7 15 PDB header:oxidoreductase/repressor Chain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition 120 c3cyvA_ not modelled 22.3 12 PDB header:lyase Chain: A: PDB Molecule:uroporphyrinogen decarboxylase; PDBTitle: crystal structure of uroporphyrinogen decarboxylase from2 shigella flexineri: new insights into its catalytic3 mechanism

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0