PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.2

Fold library entry viewer: c3pryA_

Fold library id	PDB Header	Molecule	Title
c3pryA_	PDB header: chaperone	Chain: A: PDB Molecule: heat shock protein hsp 90-beta;	PDBTitle: crystal structure of the middle domain of human hsp90-beta refined at2 2.3 a resolution

Links to external resources
Added to library: Sat Dec 18 18:29:11 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence K T K P I W T R N P D D I T Q E E Y G E F Y K S L T N D W E D H L A V K H F S V E G Q L E F R A L L F I P R R A P F K N N I K L Y V R R V F

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
G G G S
G G G
S S
S
S S S
S S
T T

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence I M D S C D E L I P E Y L N F I R G V V D S E D L P L N I S R E M L Q Q S K I L K V I R K N I V K K C L E L F S E L A E D K E N Y K K F Y E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
G G G S
G G G T T
S S S
S S
S S
T S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence A F S K N L K L G I H E D S T N R R R L S E L L R Y H T S Q S G D E M T S L S E Y V S R M K E T Q K S I Y Y I T G E S K E Q V A N S A F V E

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
G G G T
T T T T T S
T S
T T
S
T

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . .

Sequence R V R K R G F E V V Y M T E P I D E Y C V Q Q L K E F D G K S L V S V T K E G L E L A E N

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T
S T T
T T T T
S S

Download: PDB structure FASTA sequence
Hidden Markov model

Image coloured by rainbow N → C terminus

Interactive 3D view in JSmol

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Accessibility Statement

Please cite: Phyre2.2: A Community Resource for Template-based Protein Structure Prediction

Powell HR et al. Journal of Molecular Biology (2025) in press DOI: https://doi.org/10.1016/j.jmb.2025.168960

© Structural Bioinformatics Group, Imperial College, London

Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	K	T	K	P	I	W	T	R	N	P	D	D	I	T	Q	E	E	Y	G	E	F	Y	K	S	L	T	N	D	W	E	D	H	L	A	V	K	H	F	S	V	E	G	Q	L	E	F	R	A	L	L	F	I	P	R	R	A	P	F	K	N	N	I	K	L	Y	V	R	R	V	F
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S		G	G	G	S		G	G	G																	S	S			S									S	S	S										S	S												T	T
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	I	M	D	S	C	D	E	L	I	P	E	Y	L	N	F	I	R	G	V	V	D	S	E	D	L	P	L	N	I	S	R	E	M	L	Q	Q	S	K	I	L	K	V	I	R	K	N	I	V	K	K	C	L	E	L	F	S	E	L	A	E	D	K	E	N	Y	K	K	F	Y	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			S			G	G	G	S		G	G	G	T	T								S	S	S		S	S		S	S																													T	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	A	F	S	K	N	L	K	L	G	I	H	E	D	S	T	N	R	R	R	L	S	E	L	L	R	Y	H	T	S	Q	S	G	D	E	M	T	S	L	S	E	Y	V	S	R	M	K	E	T	Q	K	S	I	Y	Y	I	T	G	E	S	K	E	Q	V	A	N	S	A	F	V	E
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														G	G	G							T						T	T	T	T	T	S										T	S		T	T									S								T
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Sequence	R	V	R	K	R	G	F	E	V	V	Y	M	T	E	P	I	D	E	Y	C	V	Q	Q	L	K	E	F	D	G	K	S	L	V	S	V	T	K	E	G	L	E	L	A	E	N
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				T	T	T								S	T	T												T	T						T	T		S	S