Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP22259
DateThu Jan 5 11:38:50 GMT 2012
Unique Job IDac626557b65f9943

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1ylhA_
Top template information
PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase from2 actinobaccilus succinogenes in complex with manganese and3 pyruvate
Confidence and coverage
Confidence:100.0% Coverage: 96%
518 residues ( 96% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTG
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Disorder  ???????


































??














?
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   .........70.........80.........90.........100.........110.........120
Sequence  IFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTRQLSGKRLFV
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Disorder  ?????





















?????????























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   .........130.........140.........150.........160.........170.........180
Sequence  VDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQW
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?????


















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   .........190.........200.........210.........220.........230.........240
Sequence  KEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEK
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Disorder  ?
??


















































????
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   .........250.........260.........270.........280.........290.........300
Sequence  GDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEI
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   .........310.........320.........330.........340.........350.........360
Sequence  YNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFL
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   .........370.........380.........390.........400.........410.........420
Sequence  TADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQ
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?????????????????







??
?




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   .........430.........440.........450.........460.........470.........480
Sequence  YAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNL
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   .........490.........500.........510.........520.........530.........540
Sequence  AIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
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Disorder 







??
?































??
???



??????
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Sequence 
Secondary structure 
SS confidence 
Disorder 
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1ylh chain A

3D model

Region: 10 - 539
Aligned: 518
Modelled: 530
Confidence: 100.0%
Identity: 77%
PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase from2 actinobaccilus succinogenes in complex with manganese and3 pyruvate

Phyre2

PDB 2pc9 chain B

3D model

Region: 10 - 539
Aligned: 504
Modelled: 530
Confidence: 100.0%
Identity: 49%
PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase [atp];
PDBTitle: crystal structure of atp-dependent phosphoenolpyruvate carboxykinase2 from thermus thermophilus hb8

Phyre2

PDB 1yvy chain A

3D model

Region: 9 - 524
Aligned: 504
Modelled: 506
Confidence: 100.0%
Identity: 67%
PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase [atp];
PDBTitle: crystal strucutre of anaerobiospirillum succiniciproducens2 phosphoenolpyruvate carboxykinase

Phyre2

PDB 1ii2 chain B

3D model

Region: 23 - 540
Aligned: 499
Modelled: 518
Confidence: 100.0%
Identity: 45%
PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase2 (pepck) from trypanosoma cruzi

Phyre2

PDB 2olr chain A domain 1

3D model

Region: 228 - 540
Aligned: 313
Modelled: 313
Confidence: 100.0%
Identity: 100%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: PEP carboxykinase C-terminal domain

Phyre2

PDB 1ii2 chain A domain 1

3D model

Region: 228 - 540
Aligned: 312
Modelled: 313
Confidence: 100.0%
Identity: 47%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: PEP carboxykinase C-terminal domain

Phyre2

PDB 2fah chain B

3D model

Region: 13 - 536
Aligned: 507
Modelled: 516
Confidence: 100.0%
Identity: 17%
PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: the structure of mitochondrial pepck, complex with mn and gdp

Phyre2

PDB 1j3b chain A domain 1

3D model

Region: 228 - 540
Aligned: 302
Modelled: 313
Confidence: 100.0%
Identity: 54%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: PEP carboxykinase C-terminal domain

Phyre2

PDB 2zci chain D

3D model

Region: 13 - 536
Aligned: 498
Modelled: 512
Confidence: 100.0%
Identity: 14%
PDB header:signaling protein, lyase
Chain: D: PDB Molecule:phosphoenolpyruvate carboxykinase [gtp];
PDBTitle: structure of a gtp-dependent bacterial pep-carboxykinase2 from corynebacterium glutamicum

Phyre2

PDB 2qey chain A

3D model

Region: 13 - 535
Aligned: 505
Modelled: 523
Confidence: 100.0%
Identity: 16%
PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase, cytosolic [gtp];
PDBTitle: rat cytosolic pepck in complex with gtp

Phyre2

PDB 2olr chain A domain 2

3D model

Region: 6 - 227
Aligned: 222
Modelled: 222
Confidence: 100.0%
Identity: 100%
Fold: PEP carboxykinase N-terminal domain
Superfamily: PEP carboxykinase N-terminal domain
Family: PEP carboxykinase N-terminal domain

Phyre2

PDB 1j3b chain A domain 2

3D model

Region: 10 - 227
Aligned: 204
Modelled: 218
Confidence: 100.0%
Identity: 40%
Fold: PEP carboxykinase N-terminal domain
Superfamily: PEP carboxykinase N-terminal domain
Family: PEP carboxykinase N-terminal domain

Phyre2

PDB 1ii2 chain A domain 2

3D model

Region: 23 - 227
Aligned: 193
Modelled: 205
Confidence: 100.0%
Identity: 40%
Fold: PEP carboxykinase N-terminal domain
Superfamily: PEP carboxykinase N-terminal domain
Family: PEP carboxykinase N-terminal domain

Phyre2

PDB 1khb chain A domain 1

3D model

Region: 228 - 535
Aligned: 292
Modelled: 308
Confidence: 100.0%
Identity: 18%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: PEP carboxykinase C-terminal domain

Phyre2

PDB 1khb chain A domain 2

3D model

Region: 1 - 227
Aligned: 226
Modelled: 227
Confidence: 100.0%
Identity: 14%
Fold: PEP carboxykinase N-terminal domain
Superfamily: PEP carboxykinase N-terminal domain
Family: PEP carboxykinase N-terminal domain

Phyre2

PDB 3tqf chain A

3D model

Region: 230 - 277
Aligned: 47
Modelled: 48
Confidence: 95.5%
Identity: 23%
PDB header:transferase, hydrolase
Chain: A: PDB Molecule:hpr(ser) kinase;
PDBTitle: structure of the hpr(ser) kinase/phosphatase from coxiella burnetii

Phyre2

PDB 1knx chain A domain 2

3D model

Region: 229 - 277
Aligned: 48
Modelled: 49
Confidence: 94.9%
Identity: 25%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: HPr kinase HprK C-terminal domain

Phyre2

PDB 1kkm chain A

3D model

Region: 229 - 277
Aligned: 48
Modelled: 49
Confidence: 94.7%
Identity: 29%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: HPr kinase HprK C-terminal domain

Phyre2

PDB 1ko7 chain A domain 2

3D model

Region: 229 - 277
Aligned: 48
Modelled: 49
Confidence: 94.7%
Identity: 25%
Fold: PEP carboxykinase-like
Superfamily: PEP carboxykinase-like
Family: HPr kinase HprK C-terminal domain

Phyre2

PDB 2qmh chain K

3D model

Region: 230 - 277
Aligned: 47
Modelled: 48
Confidence: 94.5%
Identity: 30%
PDB header:transferase
Chain: K: PDB Molecule:hpr kinase/phosphorylase;
PDBTitle: structure of v267f mutant hprk/p

Phyre2
1

c1ylhA_
2

c2pc9B_
3

c1yvyA_
4

c1ii2B_
5

d2olra1
6

d1ii2a1
7

c2fahB_
8

d1j3ba1
9

c2zciD_
10

c2qeyA_
11

d2olra2
12

d1j3ba2
13

d1ii2a2
14

d1khba1
15

d1khba2
16

c3tqfA_
17

d1knxa2
18

d1kkma_
19

d1ko7a2
20

c2qmhK_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1ylhA_



100.0 77 PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase from2 actinobaccilus succinogenes in complex with manganese and3 pyruvate
2c2pc9B_



100.0 49 PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase [atp];
PDBTitle: crystal structure of atp-dependent phosphoenolpyruvate carboxykinase2 from thermus thermophilus hb8
3c1yvyA_



100.0 67 PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase [atp];
PDBTitle: crystal strucutre of anaerobiospirillum succiniciproducens2 phosphoenolpyruvate carboxykinase
4c1ii2B_



100.0 45 PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: crystal structure of phosphoenolpyruvate carboxykinase2 (pepck) from trypanosoma cruzi
5d2olra1



100.0 100 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:PEP carboxykinase C-terminal domain
6d1ii2a1



100.0 47 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:PEP carboxykinase C-terminal domain
7c2fahB_



100.0 17 PDB header:lyase
Chain: B: PDB Molecule:phosphoenolpyruvate carboxykinase;
PDBTitle: the structure of mitochondrial pepck, complex with mn and gdp
8d1j3ba1



100.0 54 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:PEP carboxykinase C-terminal domain
9c2zciD_



100.0 14 PDB header:signaling protein, lyase
Chain: D: PDB Molecule:phosphoenolpyruvate carboxykinase [gtp];
PDBTitle: structure of a gtp-dependent bacterial pep-carboxykinase2 from corynebacterium glutamicum
10c2qeyA_



100.0 16 PDB header:lyase
Chain: A: PDB Molecule:phosphoenolpyruvate carboxykinase, cytosolic [gtp];
PDBTitle: rat cytosolic pepck in complex with gtp
11d2olra2



100.0 100 Fold:PEP carboxykinase N-terminal domain
Superfamily:PEP carboxykinase N-terminal domain
Family:PEP carboxykinase N-terminal domain
12d1j3ba2



100.0 40 Fold:PEP carboxykinase N-terminal domain
Superfamily:PEP carboxykinase N-terminal domain
Family:PEP carboxykinase N-terminal domain
13d1ii2a2



100.0 40 Fold:PEP carboxykinase N-terminal domain
Superfamily:PEP carboxykinase N-terminal domain
Family:PEP carboxykinase N-terminal domain
14d1khba1



100.0 18 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:PEP carboxykinase C-terminal domain
15d1khba2



100.0 14 Fold:PEP carboxykinase N-terminal domain
Superfamily:PEP carboxykinase N-terminal domain
Family:PEP carboxykinase N-terminal domain
16c3tqfA_



95.5 23 PDB header:transferase, hydrolase
Chain: A: PDB Molecule:hpr(ser) kinase;
PDBTitle: structure of the hpr(ser) kinase/phosphatase from coxiella burnetii
17d1knxa2



94.9 25 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:HPr kinase HprK C-terminal domain
18d1kkma_



94.7 29 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:HPr kinase HprK C-terminal domain
19d1ko7a2



94.7 25 Fold:PEP carboxykinase-like
Superfamily:PEP carboxykinase-like
Family:HPr kinase HprK C-terminal domain
20c2qmhK_



94.5 30 PDB header:transferase
Chain: K: PDB Molecule:hpr kinase/phosphorylase;
PDBTitle: structure of v267f mutant hprk/p
21c1xnjB_



not modelled 94.2 52 PDB header:transferase
Chain: B: PDB Molecule:bifunctional 3'-phosphoadenosine 5'-phosphosulfate
PDBTitle: aps complex of human paps synthetase 1
22d1qzxa3



not modelled 93.0 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
23d1x6va3



not modelled 92.7 48 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Adenosine-5'phosphosulfate kinase (APS kinase)
24c3cr8C_



not modelled 92.3 50 PDB header:transferase
Chain: C: PDB Molecule:sulfate adenylyltranferase, adenylylsulfate
PDBTitle: hexameric aps kinase from thiobacillus denitrificans
25d2qy9a2



not modelled 92.3 40 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
26d1okkd2



not modelled 91.7 47 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
27c2yvuA_



not modelled 91.7 48 PDB header:transferase
Chain: A: PDB Molecule:probable adenylyl-sulfate kinase;
PDBTitle: crystal structure of ape1195
28d1m8pa3



not modelled 91.7 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ATP sulfurylase C-terminal domain
29c3pihA_



not modelled 91.5 41 PDB header:hydrolase/dna
Chain: A: PDB Molecule:uvrabc system protein a;
PDBTitle: t. maritima uvra in complex with fluorescein-modified dna
30c2ygrD_



not modelled 91.4 45 PDB header:hydrolase
Chain: D: PDB Molecule:uvrabc system protein a;
PDBTitle: mycobacterium tuberculosis uvra
31d1m7gb_



not modelled 91.3 40 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Adenosine-5'phosphosulfate kinase (APS kinase)
32c2j41A_



not modelled 91.1 53 PDB header:transferase
Chain: A: PDB Molecule:guanylate kinase;
PDBTitle: crystal structure of staphylococcus aureus guanylate2 monophosphate kinase
33c3cmvG_



not modelled 90.9 32 PDB header:recombination
Chain: G: PDB Molecule:protein reca;
PDBTitle: mechanism of homologous recombination from the reca-2 ssdna/dsdna structures
34d1knqa_



not modelled 90.9 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Gluconate kinase
35d1zp6a1



not modelled 90.8 33 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Atu3015-like
36d1vmaa2



not modelled 90.6 47 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
37d1ls1a2



not modelled 90.6 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
38c2vf7B_



not modelled 90.5 36 PDB header:dna-binding protein
Chain: B: PDB Molecule:excinuclease abc, subunit a.;
PDBTitle: crystal structure of uvra2 from deinococcus radiodurans
39d1m7ga_



not modelled 90.4 38 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Adenosine-5'phosphosulfate kinase (APS kinase)
40d1ukza_



not modelled 90.2 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
41c1m8pB_



not modelled 90.2 20 PDB header:transferase
Chain: B: PDB Molecule:sulfate adenylyltransferase;
PDBTitle: crystal structure of p. chrysogenum atp sulfurylase in the t-state
42c1ko7B_



not modelled 90.2 28 PDB header:transferase,hydrolase
Chain: B: PDB Molecule:hpr kinase/phosphatase;
PDBTitle: x-ray structure of the hpr kinase/phosphatase from2 staphylococcus xylosus at 1.95 a resolution
43d1yj5a2



not modelled 90.1 33 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
44d1ki9a_



not modelled 89.7 37 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
45c3akcA_



not modelled 89.7 21 PDB header:transferase
Chain: A: PDB Molecule:cytidylate kinase;
PDBTitle: crystal structure of cmp kinase in complex with cdp and adp from2 thermus thermophilus hb8
46d3adka_



not modelled 89.7 30 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
47d1ly1a_



not modelled 89.6 31 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
48c1ly1A_



not modelled 89.6 31 PDB header:transferase
Chain: A: PDB Molecule:polynucleotide kinase;
PDBTitle: structure and mechanism of t4 polynucleotide kinase
49d1y63a_



not modelled 89.5 40 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
50d1tmka_



not modelled 89.4 40 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
51d1qhxa_



not modelled 89.3 21 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Chloramphenicol phosphotransferase
52c2vliB_



not modelled 89.3 26 PDB header:transferase
Chain: B: PDB Molecule:antibiotic resistance protein;
PDBTitle: structure of deinococcus radiodurans tunicamycin resistance2 protein
53c2f1rA_



not modelled 89.2 17 PDB header:biosynthetic protein
Chain: A: PDB Molecule:molybdopterin-guanine dinucleotide biosynthesis
PDBTitle: crystal structure of molybdopterin-guanine biosynthesis2 protein b (mobb)
54c2plrB_



not modelled 89.0 37 PDB header:transferase
Chain: B: PDB Molecule:probable thymidylate kinase;
PDBTitle: crystal structure of dtmp kinase (st1543) from sulfolobus tokodaii2 strain7
55c3d31B_



not modelled 89.0 42 PDB header:transport protein
Chain: B: PDB Molecule:sulfate/molybdate abc transporter, atp-binding
PDBTitle: modbc from methanosarcina acetivorans
56c1oxtB_



not modelled 88.9 26 PDB header:transport protein
Chain: B: PDB Molecule:abc transporter, atp binding protein;
PDBTitle: crystal structure of glcv, the abc-atpase of the glucose abc2 transporter from sulfolobus solfataricus
57c2yz2B_



not modelled 88.8 37 PDB header:hydrolase
Chain: B: PDB Molecule:putative abc transporter atp-binding protein tm_0222;
PDBTitle: crystal structure of the abc transporter in the cobalt transport2 system
58c2grjH_



not modelled 88.8 44 PDB header:transferase
Chain: H: PDB Molecule:dephospho-coa kinase;
PDBTitle: crystal structure of dephospho-coa kinase (ec 2.7.1.24)2 (dephosphocoenzyme a kinase) (tm1387) from thermotoga maritima at3 2.60 a resolution
59c2ql6H_



not modelled 88.7 37 PDB header:signaling protein,transferase
Chain: H: PDB Molecule:nicotinamide riboside kinase 1;
PDBTitle: human nicotinamide riboside kinase (nrk1)
60d1e4va1



not modelled 88.7 29 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
61c2jatA_



not modelled 88.7 50 PDB header:transferase
Chain: A: PDB Molecule:deoxyguanosine kinase;
PDBTitle: structure of deoxyadenosine kinase from m.mycoides with2 products dcmp and a flexible dcdp bound
62d1kaga_



not modelled 88.6 37 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Shikimate kinase (AroK)
63c2yyzA_



not modelled 88.5 42 PDB header:transport protein
Chain: A: PDB Molecule:sugar abc transporter, atp-binding protein;
PDBTitle: crystal structure of sugar abc transporter, atp-binding protein
64c2rhmD_



not modelled 88.5 40 PDB header:unknown function
Chain: D: PDB Molecule:putative kinase;
PDBTitle: crystal structure of a putative kinase (caur_3907) from chloroflexus2 aurantiacus j-10-fl at 1.70 a resolution
65c3cm0A_



not modelled 88.4 37 PDB header:transferase
Chain: A: PDB Molecule:adenylate kinase;
PDBTitle: crystal structure of adenylate kinase from thermus2 thermophilus hb8
66c3tauB_



not modelled 88.3 44 PDB header:transferase
Chain: B: PDB Molecule:guanylate kinase;
PDBTitle: crystal structure of a putative guanylate monophosphaste kinase from2 listeria monocytogenes egd-e
67c2qz4A_



not modelled 88.3 34 PDB header:hydrolase
Chain: A: PDB Molecule:paraplegin;
PDBTitle: human paraplegin, aaa domain in complex with adp
68c1z47B_



not modelled 88.3 42 PDB header:ligand binding protein
Chain: B: PDB Molecule:putative abc-transporter atp-binding protein;
PDBTitle: structure of the atpase subunit cysa of the putative2 sulfate atp-binding cassette (abc) transporter from3 alicyclobacillus acidocaldarius
69d2vp4a1



not modelled 88.3 33 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
70d1akya1



not modelled 88.3 43 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
71d1g8fa3



not modelled 88.2 20 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ATP sulfurylase C-terminal domain
72c2d3wB_



not modelled 88.1 42 PDB header:biosynthetic protein
Chain: B: PDB Molecule:probable atp-dependent transporter sufc;
PDBTitle: crystal structure of escherichia coli sufc, an atpase2 compenent of the suf iron-sulfur cluster assembly machinery
73c3fvqB_



not modelled 88.1 47 PDB header:hydrolase
Chain: B: PDB Molecule:fe(3+) ions import atp-binding protein fbpc;
PDBTitle: crystal structure of the nucleotide binding domain fbpc2 complexed with atp
74c2ghiD_



not modelled 88.1 32 PDB header:transport protein
Chain: D: PDB Molecule:transport protein;
PDBTitle: crystal structure of plasmodium yoelii multidrug resistance2 protein 2
75d1k6ma1



not modelled 88.0 38 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
76c1q1bD_



not modelled 88.0 53 PDB header:transport protein
Chain: D: PDB Molecule:maltose/maltodextrin transport atp-binding protein malk;
PDBTitle: crystal structure of e. coli malk in the nucleotide-free form
77c3gd7C_



not modelled 87.9 37 PDB header:hydrolase
Chain: C: PDB Molecule:fusion complex of cystic fibrosis transmembrane
PDBTitle: crystal structure of human nbd2 complexed with n6-2 phenylethyl-atp (p-atp)
78c2vp4D_



not modelled 87.8 32 PDB header:transferase
Chain: D: PDB Molecule:deoxynucleoside kinase;
PDBTitle: structural studies of nucleoside analog and feedback2 inhibitor binding to drosophila melanogaster3 multisubstrate deoxyribonucleoside kinase
79d1g2912



not modelled 87.8 42 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
80d1qf9a_



not modelled 87.8 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
81d1ak2a1



not modelled 87.8 45 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
82c3t61A_



not modelled 87.7 30 PDB header:transferase
Chain: A: PDB Molecule:gluconokinase;
PDBTitle: crystal structure of a gluconokinase from sinorhizobium meliloti 1021
83c2z0hA_



not modelled 87.6 38 PDB header:transferase
Chain: A: PDB Molecule:thymidylate kinase;
PDBTitle: crystal structure of thymidylate kinase in complex with dtdp2 and adp from thermotoga maritima
84c3tlxA_



not modelled 87.6 33 PDB header:transferase
Chain: A: PDB Molecule:adenylate kinase 2;
PDBTitle: crystal structure of pf10_0086, adenylate kinase from plasmodium2 falciparum
85d1nn5a_



not modelled 87.6 35 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
86d1e6ca_



not modelled 87.6 26 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Shikimate kinase (AroK)
87c3nwjB_



not modelled 87.5 37 PDB header:transferase
Chain: B: PDB Molecule:atsk2;
PDBTitle: crystal structure of shikimate kinase from arabidopsis thaliana2 (atsk2)
88d2iyva1



not modelled 87.4 50 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Shikimate kinase (AroK)
89c3a4mB_



not modelled 87.4 44 PDB header:transferase
Chain: B: PDB Molecule:l-seryl-trna(sec) kinase;
PDBTitle: crystal structure of archaeal o-phosphoseryl-trna(sec)2 kinase
90c2nq2C_



not modelled 87.4 47 PDB header:metal transport
Chain: C: PDB Molecule:hypothetical abc transporter atp-binding protein
PDBTitle: an inward-facing conformation of a putative metal-chelate2 type abc transporter.
91d1l2ta_



not modelled 87.3 37 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
92d1np6a_



not modelled 87.2 60 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
93c3bosA_



not modelled 87.1 24 PDB header:hydrolase regulator,dna binding protein
Chain: A: PDB Molecule:putative dna replication factor;
PDBTitle: crystal structure of a putative dna replication regulator hda2 (sama_1916) from shewanella amazonensis sb2b at 1.75 a resolution
94d1viaa_



not modelled 87.1 50 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Shikimate kinase (AroK)
95c3b9pA_



not modelled 87.1 19 PDB header:hydrolase
Chain: A: PDB Molecule:cg5977-pa, isoform a;
PDBTitle: spastin
96c3be4A_



not modelled 87.1 29 PDB header:transferase
Chain: A: PDB Molecule:adenylate kinase;
PDBTitle: crystal structure of cryptosporidium parvum adenylate kinase cgd5_3360
97c1vciA_



not modelled 87.0 47 PDB header:transport protein
Chain: A: PDB Molecule:sugar-binding transport atp-binding protein;
PDBTitle: crystal structure of the atp-binding cassette of multisugar2 transporter from pyrococcus horikoshii ot3 complexed with3 atp
98c2gksB_



not modelled 86.9 30 PDB header:transferase
Chain: B: PDB Molecule:bifunctional sat/aps kinase;
PDBTitle: crystal structure of the bi-functional atp sulfurylase-aps kinase from2 aquifex aeolicus, a chemolithotrophic thermophile
99c2bwjC_



not modelled 86.9 30 PDB header:transferase
Chain: C: PDB Molecule:adenylate kinase 5;
PDBTitle: structure of adenylate kinase 5
100c2pt5D_



not modelled 86.9 29 PDB header:transferase
Chain: D: PDB Molecule:shikimate kinase;
PDBTitle: crystal structure of shikimate kinase (aq_2177) from aquifex aeolicus2 vf5
101c3asyB_



not modelled 86.9 44 PDB header:transferase
Chain: B: PDB Molecule:uridine kinase;
PDBTitle: ligand-free structure of uridine kinase from thermus thermophilus hb8
102d1b0ua_



not modelled 86.8 47 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
103c1zuiA_



not modelled 86.8 43 PDB header:transferase
Chain: A: PDB Molecule:shikimate kinase;
PDBTitle: structural basis for shikimate-binding specificity of helicobacter2 pylori shikimate kinase
104d1v5wa_



not modelled 86.8 43 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
105d1v43a3



not modelled 86.6 47 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
106c2it1B_



not modelled 86.5 42 PDB header:transport protein
Chain: B: PDB Molecule:362aa long hypothetical maltose/maltodextrin
PDBTitle: structure of ph0203 protein from pyrococcus horikoshii
107c2olkD_



not modelled 86.4 47 PDB header:hydrolase
Chain: D: PDB Molecule:amino acid abc transporter;
PDBTitle: abc protein artp in complex with adp-beta-s
108d1nksa_



not modelled 86.3 31 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
109d1nlfa_



not modelled 86.3 32 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:RecA protein-like (ATPase-domain)
110d1uf9a_



not modelled 86.2 25 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
111d1mv5a_



not modelled 86.1 37 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:ABC transporter ATPase domain-like
112d2bdta1



not modelled 86.0 31 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Atu3015-like
113d1khta_



not modelled 86.0 44 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nucleotide and nucleoside kinases
114c3ozxA_



not modelled 85.9 25 PDB header:hydrolase, translation
Chain: A: PDB Molecule:rnase l inhibitor;
PDBTitle: crystal structure of abce1 of sulfolubus solfataricus (-fes domain)
115c2wwiC_



not modelled 85.9 50 PDB header:transferase
Chain: C: PDB Molecule:thymidilate kinase, putative;
PDBTitle: plasmodium falciparum thymidylate kinase in complex with2 aztmp and adp
116c1g8gB_



not modelled 85.9 20 PDB header:transferase
Chain: B: PDB Molecule:sulfate adenylyltransferase;
PDBTitle: atp sulfurylase from s. cerevisiae: the binary product complex with2 aps
117d1bifa1



not modelled 85.8 44 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, kinase domain
118c2j7pA_



not modelled 85.8 24 PDB header:signal recognition
Chain: A: PDB Molecule:signal recognition particle protein;
PDBTitle: gmppnp-stabilized ng domain complex of the srp gtpases ffh2 and ftsy
119d1xjca_



not modelled 85.8 41 Fold:P-loop containing nucleoside triphosphate hydrolases
Superfamily:P-loop containing nucleoside triphosphate hydrolases
Family:Nitrogenase iron protein-like
120c1knxF_



not modelled 85.7 23 PDB header:transferase/hydrolase
Chain: F: PDB Molecule:probable hpr(ser) kinase/phosphatase;
PDBTitle: hpr kinase/phosphatase from mycoplasma pneumoniae

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0