Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	I	I	A	L	M	L	F	L	T	F	F	A	H	A	N	D	S	E	P	G	S	Q	Y	L	K	A	A	E	A	G	D	R	R	A	Q	Y	F	L	A	D	S	W	F	S	S	G	D	L	S	K	A	E	Y	W	A	Q	K
Secondary structure
SS confidence
Disorder		?														?																																?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		A	A	D	S	G	D	A	D	A	C	A	L	L	A	Q	I	K	I	T	N	P	V	S	L	D	Y	P	Q	A	K	V	L	A	E	K	A	A	Q	A	G	S	K	E	G	E	V	T	L	A	H	I	L	V	N	T	Q	A	G	K	P
Secondary structure
SS confidence
Disorder							?															?	?		?																	?																	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		D	Y	P	K	A	I	S	L	L	E	N	A	S	E	D	L	E	N	D	S	A	V	D	A	Q	M	L	L	G	L	I	Y	A	N	G	V	G	I	K	A	D	D	D	K	A	T	W	Y	F	K	R	S	S	A	I	S	R	T	G	Y
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?																			?															?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Sequence		S	E	Y	W	A	G	M	M	F	L	N	G	E	E	G	F	I	E	K	N	K	Q	K	A	L	H	W	L	N	L	S	C	M	E	G	F	D	T	G	C	E	E	F	E	K	L	T	N	G
Secondary structure
SS confidence
Disorder																?	?	?																		?	?											?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3rjv chain A Region: 21 - 228 Aligned: 208 Modelled: 208 Confidence: 100.0% Identity: 68% PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution Phyre2 PDB 1ouv chain A Region: 5 - 228 Aligned: 222 Modelled: 224 Confidence: 99.9% Identity: 14% Fold: alpha-alpha superhelix Superfamily: HCP-like Family: HCP-like Phyre2 PDB 3e4b chain D Region: 4 - 229 Aligned: 216 Modelled: 226 Confidence: 99.9% Identity: 15% PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r Phyre2 PDB 2xm6 chain A Region: 5 - 228 Aligned: 222 Modelled: 222 Confidence: 99.9% Identity: 25% PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain Phyre2 PDB 1klx chain A Region: 11 - 223 Aligned: 133 Modelled: 135 Confidence: 99.8% Identity: 14% Fold: alpha-alpha superhelix Superfamily: HCP-like Family: HCP-like Phyre2 PDB 2pl2 chain A Region: 36 - 227 Aligned: 186 Modelled: 192 Confidence: 98.2% Identity: 12% PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 Phyre2 PDB 2q7f chain A Region: 22 - 224 Aligned: 189 Modelled: 203 Confidence: 98.1% Identity: 12% PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site Phyre2 PDB 1fch chain B Region: 6 - 213 Aligned: 197 Modelled: 208 Confidence: 98.0% Identity: 13% PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 Phyre2 PDB 3hym chain B Region: 5 - 227 Aligned: 217 Modelled: 223 Confidence: 98.0% Identity: 12% PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure Phyre2 PDB 3cvp chain A Region: 6 - 227 Aligned: 216 Modelled: 222 Confidence: 97.8% Identity: 11% PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) Phyre2 PDB 1fch chain A Region: 6 - 213 Aligned: 197 Modelled: 208 Confidence: 97.7% Identity: 13% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 2vq2 chain A Region: 5 - 223 Aligned: 209 Modelled: 215 Confidence: 97.7% Identity: 11% PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor Phyre2 PDB 1xnf chain A Region: 5 - 228 Aligned: 212 Modelled: 218 Confidence: 97.6% Identity: 9% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 PDB 3pe3 chain D Region: 5 - 227 Aligned: 140 Modelled: 146 Confidence: 97.5% Identity: 17% PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate Phyre2 PDB 3sf4 chain B Region: 10 - 227 Aligned: 212 Modelled: 212 Confidence: 97.5% Identity: 17% PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn Phyre2 PDB 3q15 chain A Region: 4 - 213 Aligned: 204 Modelled: 210 Confidence: 97.5% Identity: 16% PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f Phyre2 PDB 2ho1 chain B Region: 35 - 226 Aligned: 180 Modelled: 192 Confidence: 97.4% Identity: 12% PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf Phyre2 PDB 3as5 chain A Region: 1 - 213 Aligned: 165 Modelled: 171 Confidence: 97.4% Identity: 11% PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 Phyre2 PDB 2ifu chain A Region: 20 - 226 Aligned: 201 Modelled: 207 Confidence: 97.3% Identity: 16% PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio Phyre2 PDB 3gw4 chain B Region: 16 - 229 Aligned: 185 Modelled: 191 Confidence: 97.1% Identity: 12% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. Phyre2 PDB 1hxi chain A Region: 6 - 93 Aligned: 88 Modelled: 85 Confidence: 96.8% Identity: 15% Fold: alpha-alpha superhelix Superfamily: TPR-like Family: Tetratricopeptide repeat (TPR) Phyre2 1 c3rjvA_ 2 d1ouva_ 3 c3e4bD_ 4 c2xm6A_ 5 d1klxa_ 6 c2pl2A_ 7 c2q7fA_ 8 c1fchB_ 9 c3hymB_ 10 c3cvpA_ 11 d1fcha_ 12 c2vq2A_ 13 d1xnfa_ 14 c3pe3D_ 15 c3sf4B_ 16 c3q15A_ 17 c2ho1B_ 18 c3as5A_ 19 c2ifuA_ 20 c3gw4B_ 21 22 23 24 25 d1hxia_ 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3rjvA_ 100.0 68 PDB header:protein binding Chain: A: PDB Molecule:putative sel1 repeat protein; PDBTitle: crystal structure of a putative sel1 repeat protein (kpn_04481) from2 klebsiella pneumoniae subsp. pneumoniae at 1.65 a resolution 2 d1ouva_ 99.9 14 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 3 c3e4bD_ 99.9 15 PDB header:protein binding Chain: D: PDB Molecule:algk; PDBTitle: crystal structure of algk from pseudomonas fluorescens wcs374r 4 c2xm6A_ 99.9 25 PDB header:unknown function Chain: A: PDB Molecule:protein corresponding to locus c5321 from cft073 e.coli PDBTitle: crystal structure of the protein corresponding to locus c5321 from2 cft073 e.coli strain 5 d1klxa_ 99.8 14 Fold:alpha-alpha superhelix Superfamily:HCP-like Family:HCP-like 6 c2pl2A_ 98.2 12 PDB header:protein binding Chain: A: PDB Molecule:hypothetical conserved protein ttc0263; PDBTitle: crystal structure of ttc0263: a thermophilic tpr protein in thermus2 thermophilus hb27 7 c2q7fA_ 98.1 12 PDB header:protein binding Chain: A: PDB Molecule:yrrb protein; PDBTitle: crystal structure of yrrb: a tpr protein with an unusual peptide-2 binding site 8 c1fchB_ 98.0 13 PDB header:signaling protein Chain: B: PDB Molecule:peroxisomal targeting signal 1 receptor; PDBTitle: crystal structure of the pts1 complexed to the tpr region2 of human pex5 9 c3hymB_ 98.0 12 PDB header:cell cycle, ligase Chain: B: PDB Molecule:cell division cycle protein 16 homolog; PDBTitle: insights into anaphase promoting complex tpr subdomain2 assembly from a cdc26-apc6 structure 10 c3cvpA_ 97.8 11 PDB header:transport protein Chain: A: PDB Molecule:peroxisome targeting signal 1 receptor pex5; PDBTitle: structure of peroxisomal targeting signal 1 (pts1) binding2 domain of trypanosoma brucei peroxin 5 (tbpex5)complexed3 to pts1 peptide (10-skl) 11 d1fcha_ 97.7 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 12 c2vq2A_ 97.7 11 PDB header:structural protein Chain: A: PDB Molecule:putative fimbrial biogenesis and twitching PDBTitle: crystal structure of pilw, widely conserved type iv pilus2 biogenesis factor 13 d1xnfa_ 97.6 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 14 c3pe3D_ 97.5 17 PDB header:transferase Chain: D: PDB Molecule:udp-n-acetylglucosamine--peptide n- PDBTitle: structure of human o-glcnac transferase and its complex with a peptide2 substrate 15 c3sf4B_ 97.5 17 PDB header:signaling protein/protein binding Chain: B: PDB Molecule:g-protein-signaling modulator 2; PDBTitle: crystal structure of the complex between the conserved cell polarity2 proteins inscuteable and lgn 16 c3q15A_ 97.5 16 PDB header:hydrolase/kinase Chain: A: PDB Molecule:response regulator aspartate phosphatase h; PDBTitle: crystal structure of raph complexed with spo0f 17 c2ho1B_ 97.4 12 PDB header:protein binding Chain: B: PDB Molecule:type 4 fimbrial biogenesis protein pilf; PDBTitle: functional characterization of pseudomonas aeruginosa pilf 18 c3as5A_ 97.4 11 PDB header:protein binding Chain: A: PDB Molecule:mama; PDBTitle: mama amb-1 p212121 19 c2ifuA_ 97.3 16 PDB header:endocytosis/exocytosis Chain: A: PDB Molecule:gamma-snap; PDBTitle: crystal structure of a gamma-snap from danio rerio 20 c3gw4B_ 97.1 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of uncharacterized protein from deinococcus2 radiodurans. northeast structural genomics consortium target drr162b. 21 c1wao4_ not modelled 97.0 16 PDB header:hydrolase Chain: 4: PDB Molecule:serine/threonine protein phosphatase 5; PDBTitle: pp5 structure 22 c3ulqA_ not modelled 96.9 11 PDB header:gene regulation/transcription activator Chain: A: PDB Molecule:response regulator aspartate phosphatase f; PDBTitle: crystal structure of the anti-activator rapf complexed with the2 response regulator coma dna binding domain 23 c2xpiA_ not modelled 96.9 10 PDB header:cell cycle Chain: A: PDB Molecule:anaphase-promoting complex subunit cut9; PDBTitle: crystal structure of apc/c hetero-tetramer cut9-hcn1 24 c3beeB_ not modelled 96.9 21 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative yfre protein; PDBTitle: crystal structure of putative yfre protein from vibrio2 parahaemolyticus 25 d1hxia_ 96.8 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 26 c2if4A_ not modelled 96.8 16 PDB header:signaling protein Chain: A: PDB Molecule:atfkbp42; PDBTitle: crystal structure of a multi-domain immunophilin from2 arabidopsis thaliana 27 c2kcvA_ not modelled 96.6 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tetratricopeptide repeat domain protein; PDBTitle: solution nmr structure of tetratricopeptide repeat domain2 protein sru_0103 from salinibacter ruber, northeast3 structural genomics consortium (nesg) target srr115c 28 d1w3ba_ not modelled 96.6 23 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 29 c2katA_ not modelled 96.6 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: solution structure of protein bpp2914 from bordetella2 parapertussis. northeast structural genomics consortium3 target bpr206 30 c3mkrA_ not modelled 96.5 9 PDB header:transport protein Chain: A: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of yeast alpha/epsilon-cop subcomplex of the copi2 vesicular coat 31 d1tjca_ not modelled 96.5 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 32 c2gw1A_ not modelled 96.5 20 PDB header:protein transport Chain: A: PDB Molecule:mitochondrial precursor proteins import receptor; PDBTitle: crystal structure of the yeast tom70 33 c2avpA_ not modelled 96.4 23 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix 34 c3fp4A_ not modelled 96.4 25 PDB header:transport protein Chain: A: PDB Molecule:tpr repeat-containing protein yhr117w; PDBTitle: crystal structure of tom71 complexed with ssa1 c-terminal2 fragment 35 c3k9iA_ not modelled 96.4 14 PDB header:protein binding Chain: A: PDB Molecule:bh0479 protein; PDBTitle: crystal structure of putative protein binding protein (np_241345.1)2 from bacillus halodurans at 2.71 a resolution 36 c3fflC_ not modelled 96.4 13 PDB header:cell cycle Chain: C: PDB Molecule:anaphase-promoting complex subunit 7; PDBTitle: crystal structure of the n-terminal domain of anaphase-2 promoting complex subunit 7 37 c3iegB_ not modelled 96.3 19 PDB header:chaperone Chain: B: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of p58(ipk) tpr domain at 2.5 a 38 c3gyzB_ not modelled 96.2 10 PDB header:chaperone Chain: B: PDB Molecule:chaperone protein ipgc; PDBTitle: crystal structure of ipgc from shigella flexneri 39 c2vsnB_ not modelled 96.2 15 PDB header:transferase Chain: B: PDB Molecule:xcogt; PDBTitle: structure and topological arrangement of an o-glcnac2 transferase homolog: insight into molecular control of3 intracellular glycosylation 40 c2xcbA_ not modelled 96.2 12 PDB header:protein binding Chain: A: PDB Molecule:regulatory protein pcrh; PDBTitle: crystal structure of pcrh in complex with the chaperone2 binding region of popd 41 c2y4tA_ not modelled 96.2 21 PDB header:chaperone Chain: A: PDB Molecule:dnaj homolog subfamily c member 3; PDBTitle: crystal structure of the human co-chaperone p58(ipk) 42 c3draA_ not modelled 96.0 10 PDB header:transferase Chain: A: PDB Molecule:protein PDBTitle: candida albicans protein geranylgeranyltransferase-i2 complexed with ggpp 43 c3urzB_ not modelled 95.9 10 PDB header:protein binding Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a hypothetical protein (bacova_03105) from2 bacteroides ovatus atcc 8483 at 2.19 a resolution 44 d1hz4a_ not modelled 95.8 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Transcription factor MalT domain III 45 c1kt0A_ not modelled 95.7 12 PDB header:isomerase Chain: A: PDB Molecule:51 kda fk506-binding protein; PDBTitle: structure of the large fkbp-like protein, fkbp51, involved in steroid2 receptor complexes 46 c2kc7A_ not modelled 95.5 14 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:bfr218_protein; PDBTitle: solution nmr structure of bacteroides fragilis protein2 bf1650. northeast structural genomics consortium target3 bfr218 47 c2c2lD_ not modelled 95.5 16 PDB header:chaperone Chain: D: PDB Molecule:carboxy terminus of hsp70-interacting protein; PDBTitle: crystal structure of the chip u-box e3 ubiquitin ligase 48 d1p5qa1 not modelled 95.4 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 49 c2r5sB_ not modelled 95.4 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized protein vp0806; PDBTitle: the crystal structure of a domain of protein vp0806 (unknown function)2 from vibrio parahaemolyticus rimd 2210633 50 d1pc2a_ not modelled 95.1 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 51 c2kckA_ not modelled 95.0 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:tpr repeat; PDBTitle: nmr solution structure of the northeast structural genomics2 consortium (nesg) target mrr121a 52 c2l6jA_ not modelled 94.9 13 PDB header:protein binding Chain: A: PDB Molecule:tpr repeat-containing protein associated with hsp90; PDBTitle: tah1 complexed by meevd 53 c1na3A_ not modelled 94.9 23 PDB header:de novo protein Chain: A: PDB Molecule:designed protein ctpr2; PDBTitle: design of stable alpha-helical arrays from an idealized tpr2 motif 54 c3mv3B_ not modelled 94.8 9 PDB header:protein transport Chain: B: PDB Molecule:coatomer subunit epsilon; PDBTitle: crystal structure of a-cop in complex with e-cop 55 d1nzna_ not modelled 94.7 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 56 d1hh8a_ not modelled 94.6 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 57 c3qkyA_ not modelled 94.6 10 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane assembly lipoprotein yfio; PDBTitle: crystal structure of rhodothermus marinus bamd 58 c1ihgA_ not modelled 94.4 18 PDB header:isomerase Chain: A: PDB Molecule:cyclophilin 40; PDBTitle: bovine cyclophilin 40, monoclinic form 59 d1elwa_ not modelled 94.3 5 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 60 d1y8ma1 not modelled 94.2 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 61 d1elra_ not modelled 94.1 22 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 62 c3ly8A_ not modelled 94.0 12 PDB header:signaling protein Chain: A: PDB Molecule:transcriptional activator cadc; PDBTitle: crystal structure of mutant d471e of the periplasmic domain of cadc 63 c3ceqB_ not modelled 93.9 12 PDB header:motor protein, transport protein Chain: B: PDB Molecule:kinesin light chain 2; PDBTitle: the tpr domain of human kinesin light chain 2 (hklc2) 64 d1qqea_ not modelled 92.9 13 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 65 d2buga1 not modelled 92.7 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 66 d2c2la1 not modelled 92.2 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 67 c2hyzA_ not modelled 92.2 23 PDB header:de novo protein Chain: A: PDB Molecule:synthetic consensus tpr protein; PDBTitle: crystal structure of an 8 repeat consensus tpr superhelix2 (orthorombic crystal form) 68 d1iyga_ not modelled 91.9 9 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 69 c2xevB_ not modelled 91.7 17 PDB header:metal binding Chain: B: PDB Molecule:ybgf; PDBTitle: crystal structure of the tpr domain of xanthomonas2 campestris ybgf 70 d1kt1a1 not modelled 90.8 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 71 c2dbaA_ not modelled 90.7 19 PDB header:structural protein Chain: A: PDB Molecule:smooth muscle cell associated protein-1, isoform PDBTitle: the solution structure of the tetratrico peptide repeat of2 human smooth muscle cell associated protein-1, isoform 2 72 c2vgxA_ not modelled 90.7 13 PDB header:chaperone Chain: A: PDB Molecule:chaperone sycd; PDBTitle: structure of the yersinia enterocolitica type iii secretion2 translocator chaperone sycd 73 c2yhcA_ not modelled 90.7 8 PDB header:membrane protein Chain: A: PDB Molecule:upf0169 lipoprotein yfio; PDBTitle: structure of bamd from e. coli 74 c3q49B_ not modelled 90.4 14 PDB header:ligase/chaperone Chain: B: PDB Molecule:stip1 homology and u box-containing protein 1; PDBTitle: crystal structure of the tpr domain of chip complexed with hsp70-c2 peptide 75 c3nf1A_ not modelled 88.7 11 PDB header:motor protein, transport protein Chain: A: PDB Molecule:kinesin light chain 1; PDBTitle: crystal structure of the tpr domain of kinesin light chain 1 76 c3sz7A_ not modelled 88.3 12 PDB header:chaperone regulator Chain: A: PDB Molecule:hsc70 cochaperone (sgt); PDBTitle: crystal structure of the sgt2 tpr domain from aspergillus fumigatus 77 d1qsaa1 not modelled 88.0 10 Fold:alpha-alpha superhelix Superfamily:Bacterial muramidases Family:Bacterial muramidases 78 c2e2eA_ not modelled 87.8 17 PDB header:lyase Chain: A: PDB Molecule:formate-dependent nitrite reductase complex nrfg subunit; PDBTitle: tpr domain of nrfg mediates the complex formation between heme lyase2 and formate-dependent nitrite reductase in escherichia coli o157:h7 79 d1zbpa1 not modelled 87.5 11 Fold:ImpE-like Superfamily:ImpE-like Family:ImpE-like 80 d1dcea1 not modelled 87.0 4 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 81 d1d8da_ not modelled 85.9 8 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 82 d2hr2a1 not modelled 85.5 17 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:CT2138-like 83 c3rkvA_ not modelled 85.5 13 PDB header:isomerase Chain: A: PDB Molecule:putative peptidylprolyl isomerase; PDBTitle: c-terminal domain of protein c56c10.10, a putative peptidylprolyl2 isomerase, from caenorhabditis elegans 84 c2vyiA_ not modelled 85.3 11 PDB header:chaperone Chain: A: PDB Molecule:sgta protein; PDBTitle: crystal structure of the tpr domain of human sgt 85 c1slyA_ not modelled 85.2 10 PDB header:glycosyltransferase Chain: A: PDB Molecule:70-kda soluble lytic transglycosylase; PDBTitle: complex of the 70-kda soluble lytic transglycosylase with2 bulgecin a 86 d1a17a_ not modelled 84.6 16 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 87 c3q75A_ not modelled 82.9 8 PDB header:transferase Chain: A: PDB Molecule:farnesyltransferase alpha subunit; PDBTitle: cryptococcus neoformans protein farnesyltransferase in complex with2 fpt-ii and tkcvvm peptide 88 d1zu2a1 not modelled 82.5 6 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 89 c1qz2B_ not modelled 80.0 17 PDB header:isomerase/chaperone Chain: B: PDB Molecule:fk506-binding protein 4; PDBTitle: crystal structure of fkbp52 c-terminal domain complex with2 the c-terminal peptide meevd of hsp90 90 d2pqrb1 not modelled 79.9 15 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 91 c2fbnA_ not modelled 78.4 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:70 kda peptidylprolyl isomerase, putative; PDBTitle: plasmodium falciparum putative fk506-binding protein2 pfl2275c, c-terminal tpr-containing domain 92 d2fbna1 not modelled 78.4 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 93 c3qdnA_ not modelled 78.4 10 PDB header:oxidoreductase Chain: A: PDB Molecule:putative thioredoxin protein; PDBTitle: putative thioredoxin protein from salmonella typhimurium 94 d2h6fa1 not modelled 73.5 8 Fold:alpha-alpha superhelix Superfamily:Protein prenylyltransferase Family:Protein prenylyltransferase 95 c3n71A_ not modelled 71.5 9 PDB header:transcription Chain: A: PDB Molecule:histone lysine methyltransferase smyd1; PDBTitle: crystal structure of cardiac specific histone methyltransferase smyd1 96 c3mekA_ not modelled 71.4 9 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: crystal structure of human histone-lysine n-2 methyltransferase smyd3 in complex with s-adenosyl-l-3 methionine 97 d2ooea1 not modelled 68.6 10 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:HAT/Suf repeat 98 d1ihga1 not modelled 67.6 19 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 99 d1wy6a1 not modelled 63.7 22 Fold:alpha-alpha superhelix Superfamily:Hypothetical protein ST1625 Family:Hypothetical protein ST1625 100 c2uy1A_ not modelled 60.5 10 PDB header:rna-binding protein Chain: A: PDB Molecule:cleavage stimulation factor 77; PDBTitle: crystal structure of cstf-77 101 c3oxgA_ not modelled 60.2 9 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 3; PDBTitle: human lysine methyltransferase smyd3 in complex with adohcy (form iii) 102 d2ff4a2 not modelled 57.3 11 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:BTAD-like 103 c1tnoI_ not modelled 55.3 8 PDB header:transferase Chain: I: PDB Molecule:geranylgeranyltransferase type i alpha subunit; PDBTitle: rat protein geranylgeranyltransferase type-i complexed with2 a ggpp analog and a kkksktkcvim peptide derived from k-3 ras4b 104 c1xi4D_ not modelled 54.5 21 PDB header:endocytosis/exocytosis Chain: D: PDB Molecule:clathrin heavy chain; PDBTitle: clathrin d6 coat 105 d1ya0a1 not modelled 53.8 23 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 106 c3qwvA_ not modelled 45.5 8 PDB header:transferase Chain: A: PDB Molecule:set and mynd domain-containing protein 2; PDBTitle: crystal structure of histone lysine methyltransferase smyd2 in complex2 with the cofactor product adohcy 107 d1iipa1 not modelled 32.3 28 Fold:alpha-alpha superhelix Superfamily:TPR-like Family:Tetratricopeptide repeat (TPR) 108 c2hz8A_ not modelled 25.8 21 PDB header:de novo protein Chain: A: PDB Molecule:de novo designed diiron protein; PDBTitle: qm/mm structure refined from nmr-structure of a single2 chain diiron protein

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0