Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP0ADR6
DateThu Jan 5 11:21:40 GMT 2012
Unique Job IDa2f54fd99549edbe

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template d2p41a1
Top template information
Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap methylase
Confidence and coverage
Confidence: 99.9% Coverage: 40%
145 residues ( 40% of your sequence) have been modelled with 99.9% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
334 residues ( 91%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELP
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Disorder  ???
























































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   .........70.........80.........90.........100.........110.........120
Sequence  FSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFC
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?












??







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   .........130.........140.........150.........160.........170.........180
Sequence  RKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKF
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Disorder  ??









????????????





















?

??????




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   .........190.........200.........210.........220.........230.........240
Sequence  PADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVD
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Disorder  ??



















????

































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   .........250.........260.........270.........280.........290.........300
Sequence  NGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRE
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Disorder 



?

















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   .........310.........320.........330.........340.........350.........360
Sequence  TIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVG
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?












































????
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   ......
Sequence  GRRDER
Secondary structure 





SS confidence 





Disorder  ??????
Disorder confidence 





 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2p41 chain A domain 1

3D model

Region: 167 - 322
Aligned: 145
Modelled: 156
Confidence: 99.9%
Identity: 26%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: mRNA cap methylase

Phyre2

PDB 3gcz chain A

3D model

Region: 167 - 322
Aligned: 147
Modelled: 156
Confidence: 99.9%
Identity: 22%
PDB header:transferase
Chain: A: PDB Molecule:polyprotein;
PDBTitle: yokose virus methyltransferase in complex with adomet

Phyre2

PDB 3lkz chain B

3D model

Region: 151 - 327
Aligned: 161
Modelled: 177
Confidence: 99.9%
Identity: 26%
PDB header:viral protein
Chain: B: PDB Molecule:non-structural protein 5;
PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase

Phyre2

PDB 2p3q chain A

3D model

Region: 167 - 322
Aligned: 145
Modelled: 156
Confidence: 99.8%
Identity: 26%
PDB header:viral protein,transferase
Chain: A: PDB Molecule:type ii methyltransferase;
PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine

Phyre2

PDB 3eva chain A

3D model

Region: 183 - 322
Aligned: 130
Modelled: 140
Confidence: 99.8%
Identity: 25%
PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase ns5;
PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine

Phyre2

PDB 2px2 chain B

3D model

Region: 174 - 322
Aligned: 139
Modelled: 149
Confidence: 99.8%
Identity: 27%
PDB header:transferase
Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c
PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)

Phyre2

PDB 3hp7 chain A

3D model

Region: 181 - 341
Aligned: 148
Modelled: 161
Confidence: 99.7%
Identity: 24%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.

Phyre2

PDB 2wa1 chain A

3D model

Region: 185 - 322
Aligned: 129
Modelled: 138
Confidence: 99.6%
Identity: 19%
PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)

Phyre2

PDB 3dou chain A

3D model

Region: 186 - 281
Aligned: 85
Modelled: 95
Confidence: 99.5%
Identity: 28%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j;
PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1

Phyre2

PDB 2plw chain A

3D model

Region: 185 - 321
Aligned: 124
Modelled: 137
Confidence: 99.5%
Identity: 17%
PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative;
PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).

Phyre2

PDB 2nyu chain A

3D model

Region: 185 - 323
Aligned: 126
Modelled: 139
Confidence: 99.5%
Identity: 21%
PDB header:transferase
Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2;
PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine

Phyre2

PDB 1ej0 chain A

3D model

Region: 186 - 323
Aligned: 125
Modelled: 138
Confidence: 99.4%
Identity: 27%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: RNA methyltransferase FtsJ

Phyre2

PDB 3opn chain A

3D model

Region: 186 - 354
Aligned: 156
Modelled: 167
Confidence: 99.4%
Identity: 21%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis

Phyre2

PDB 1g8a chain A

3D model

Region: 191 - 354
Aligned: 159
Modelled: 164
Confidence: 98.7%
Identity: 11%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Fibrillarin homologue

Phyre2

PDB 1nt2 chain A

3D model

Region: 184 - 355
Aligned: 164
Modelled: 172
Confidence: 98.6%
Identity: 15%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Fibrillarin homologue

Phyre2

PDB 1pry chain A

3D model

Region: 191 - 355
Aligned: 160
Modelled: 165
Confidence: 98.6%
Identity: 11%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Fibrillarin homologue

Phyre2

PDB 1g8s chain A

3D model

Region: 185 - 353
Aligned: 163
Modelled: 169
Confidence: 98.6%
Identity: 12%
Fold: S-adenosyl-L-methionine-dependent methyltransferases
Superfamily: S-adenosyl-L-methionine-dependent methyltransferases
Family: Fibrillarin homologue

Phyre2

PDB 3ldu chain A

3D model

Region: 3 - 277
Aligned: 246
Modelled: 261
Confidence: 98.6%
Identity: 15%
PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.

Phyre2

PDB 2ipx chain A

3D model

Region: 185 - 355
Aligned: 165
Modelled: 171
Confidence: 98.6%
Identity: 16%
PDB header:transferase
Chain: A: PDB Molecule:rrna 2'-o-methyltransferase fibrillarin;
PDBTitle: human fibrillarin

Phyre2

PDB 3id5 chain F

3D model

Region: 191 - 354
Aligned: 156
Modelled: 164
Confidence: 98.5%
Identity: 14%
PDB header:transferase/ribosomal protein/rna
Chain: F: PDB Molecule:fibrillarin-like rrna/trna 2'-o-methyltransferase;
PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna

Phyre2
1

d2p41a1
2

c3gczA_
3

c3lkzB_
4

c2p3qA_
5

c3evaA_
6

c2px2B_
7

c3hp7A_
8

c2wa1A_
9

c3douA_
10

c2plwA_
11

c2nyuA_
12

d1ej0a_
13

c3opnA_
14

d1g8aa_
15

d1nt2a_
16

d1prya_
17

d1g8sa_
18

c3lduA_
19

c2ipxA_
20

c3id5F_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1d2p41a1



99.9 26 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:mRNA cap methylase
2c3gczA_



99.9 22 PDB header:transferase
Chain: A: PDB Molecule:polyprotein;
PDBTitle: yokose virus methyltransferase in complex with adomet
3c3lkzB_



99.9 26 PDB header:viral protein
Chain: B: PDB Molecule:non-structural protein 5;
PDBTitle: structural and functional analyses of a conserved hydrophobic pocket2 of flavivirus methyltransferase
4c2p3qA_



99.8 26 PDB header:viral protein,transferase
Chain: A: PDB Molecule:type ii methyltransferase;
PDBTitle: crystal structure of dengue methyltransferase in complex with gpppg2 and s-adenosyl-l-homocysteine
5c3evaA_



99.8 25 PDB header:transferase
Chain: A: PDB Molecule:rna-directed rna polymerase ns5;
PDBTitle: crystal structure of yellow fever virus methyltransferase complexed2 with s-adenosyl-l-homocysteine
6c2px2B_



99.8 27 PDB header:transferase
Chain: B: PDB Molecule:genome polyprotein [contains: capsid protein c
PDBTitle: crystal structure of the murray valley encephalitis virus2 ns5 2'-o methyltransferase domain in complex with sah3 (monoclinic form 1)
7c3hp7A_



99.7 24 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hemolysin, putative;
PDBTitle: putative hemolysin from streptococcus thermophilus.
8c2wa1A_



99.6 19 PDB header:transferase
Chain: A: PDB Molecule:non-structural protein 5;
PDBTitle: structure of the methyltransferase domain from modoc virus,2 a flavivirus with no known vector (nkv)
9c3douA_



99.5 28 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna large subunit methyltransferase j;
PDBTitle: crystal structure of methyltransferase involved in cell2 division from thermoplasma volcanicum gss1
10c2plwA_



99.5 17 PDB header:transferase
Chain: A: PDB Molecule:ribosomal rna methyltransferase, putative;
PDBTitle: crystal structure of a ribosomal rna methyltransferase, putative, from2 plasmodium falciparum (pf13_0052).
11c2nyuA_



99.5 21 PDB header:transferase
Chain: A: PDB Molecule:putative ribosomal rna methyltransferase 2;
PDBTitle: crystal structure of human ftsj homolog 2 (e.coli) protein2 in complex with s-adenosylmethionine
12d1ej0a_



99.4 27 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:RNA methyltransferase FtsJ
13c3opnA_



99.4 21 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative hemolysin;
PDBTitle: the crystal structure of a putative hemolysin from lactococcus lactis
14d1g8aa_



98.7 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
15d1nt2a_



98.6 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
16d1prya_



98.6 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
17d1g8sa_



98.6 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Fibrillarin homologue
18c3lduA_



98.6 15 PDB header:transferase
Chain: A: PDB Molecule:putative methylase;
PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630.
19c2ipxA_



98.6 16 PDB header:transferase
Chain: A: PDB Molecule:rrna 2'-o-methyltransferase fibrillarin;
PDBTitle: human fibrillarin
20c3id5F_



98.5 14 PDB header:transferase/ribosomal protein/rna
Chain: F: PDB Molecule:fibrillarin-like rrna/trna 2'-o-methyltransferase;
PDBTitle: crystal structure of sulfolobus solfataricus c/d rnp assembled with2 nop5, fibrillarin, l7ae and a split half c/d rna
21c3mtiA_



not modelled 98.4 11 PDB header:transferase
Chain: A: PDB Molecule:rrna methylase;
PDBTitle: the crystal structure of a rrna methylase from streptococcus2 thermophilus to 1.95a
22c3elyA_



not modelled 98.4 25 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: wesselsbron virus methyltransferase in complex with adohcy
23c3eeyJ_



not modelled 98.3 15 PDB header:transferase
Chain: J: PDB Molecule:putative rrna methylase;
PDBTitle: crystal structure of putative rrna-methylase from clostridium2 thermocellum
24c2oxtC_



not modelled 98.2 27 PDB header:viral protein
Chain: C: PDB Molecule:nucleoside-2'-o-methyltransferase;
PDBTitle: crystal structure of meaban virus nucleoside-2'-o-2 methyltransferase
25d1qama_



not modelled 98.2 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
26d1l3ia_



not modelled 98.1 22 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Precorrin-6Y methyltransferase (CbiT)
27d2i6ga1



not modelled 98.0 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:TehB-like
28d1vl5a_



not modelled 98.0 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
29c1vl5B_



not modelled 98.0 13 PDB header:transferase
Chain: B: PDB Molecule:unknown conserved protein bh2331;
PDBTitle: crystal structure of a putative methyltransferase (bh2331) from2 bacillus halodurans c-125 at 1.95 a resolution
30d1ixka_



not modelled 98.0 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
31c2yxdA_



not modelled 98.0 17 PDB header:transferase
Chain: A: PDB Molecule:probable cobalt-precorrin-6y c(15)-methyltransferase
PDBTitle: crystal structure of cobalamin biosynthesis precorrin 8w decarboxylase2 (cbit)
32d1wg8a2



not modelled 97.9 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
33d1vbfa_



not modelled 97.9 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
34c3bkxB_



not modelled 97.9 17 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of cyclopropane-fatty-acyl-phospholipid synthase-2 like protein (yp_807781.1) from lactobacillus casei atcc 334 at 1.853 a resolution
35c3grrA_



not modelled 97.9 14 PDB header:transferase
Chain: A: PDB Molecule:dimethyladenosine transferase;
PDBTitle: crystal structure of the complex between s-adenosyl homocysteine and2 methanocaldococcus jannaschi dim1.
36c3fydA_



not modelled 97.9 14 PDB header:transferase
Chain: A: PDB Molecule:probable dimethyladenosine transferase;
PDBTitle: crystal structure of dim1 from the thermophilic archeon,2 methanocaldococcus jannaschi
37c3gdhC_



not modelled 97.9 18 PDB header:transferase
Chain: C: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form)
38c3cggB_



not modelled 97.9 14 PDB header:transferase
Chain: B: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of tehb-like sam-dependent methyltransferase2 (np_600671.1) from corynebacterium glutamicum atcc 13032 kitasato at3 2.00 a resolution
39d2ex4a1



not modelled 97.9 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
40c3tqsB_



not modelled 97.9 15 PDB header:transferase
Chain: B: PDB Molecule:ribosomal rna small subunit methyltransferase a;
PDBTitle: structure of the dimethyladenosine transferase (ksga) from coxiella2 burnetii
41d1ve3a1



not modelled 97.9 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:CAC2371-like
42c2fk8A_



not modelled 97.9 17 PDB header:transferase
Chain: A: PDB Molecule:methoxy mycolic acid synthase 4;
PDBTitle: crystal structure of hma (mmaa4) from mycobacterium tuberculosis2 complexed with s-adenosylmethionine
43c3e05B_



not modelled 97.8 9 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y c5,15-methyltransferase (decarboxylating);
PDBTitle: crystal structure of precorrin-6y c5,15-methyltransferase from2 geobacter metallireducens gs-15
44c3lecA_



not modelled 97.8 9 PDB header:structure genomics, unknown function
Chain: A: PDB Molecule:nadb-rossmann superfamily protein;
PDBTitle: the crystal structure of a protein in the nadb-rossmann2 superfamily from streptococcus agalactiae to 1.8a
45c3ujcA_



not modelled 97.8 9 PDB header:transferase
Chain: A: PDB Molecule:phosphoethanolamine n-methyltransferase;
PDBTitle: phosphoethanolamine methyltransferase mutant (h132a) from plasmodium2 falciparum in complex with phosphocholine
46c3egeA_



not modelled 97.8 19 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase from antibiotic biosynthesis
PDBTitle: crystal structure of putative methyltransferase from antibiotic2 biosynthesis pathway (yp_324569.1) from anabaena variabilis atcc3 29413 at 2.40 a resolution
47d2fk8a1



not modelled 97.8 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
48c2yr0A_



not modelled 97.8 15 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha0223;
PDBTitle: crystal structure of hypothetical methyltransferase ttha0223 from2 thermus thermophilus hb8
49d1xxla_



not modelled 97.8 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
50d1dusa_



not modelled 97.8 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical protein MJ0882
51c2yxlA_



not modelled 97.8 27 PDB header:transferase
Chain: A: PDB Molecule:450aa long hypothetical fmu protein;
PDBTitle: crystal structure of ph0851
52d1dl5a1



not modelled 97.8 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
53d2igta1



not modelled 97.8 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
54c3m33B_



not modelled 97.7 13 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of a functionally unknown protein from2 deinococcus radiodurans r1
55d2nxca1



not modelled 97.7 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ribosomal protein L11 methyltransferase PrmA
56d1g6q1_



not modelled 97.7 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
57c3njrB_



not modelled 97.7 9 PDB header:transferase
Chain: B: PDB Molecule:precorrin-6y methylase;
PDBTitle: crystal structure of c-terminal domain of precorrin-6y c5,15-2 methyltransferase from rhodobacter capsulatus
58d1i9ga_



not modelled 97.7 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
59d2b78a2



not modelled 97.7 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
60d1fp2a2



not modelled 97.7 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Plant O-methyltransferase, C-terminal domain
61d2fyta1



not modelled 97.7 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
62c3mggB_



not modelled 97.7 21 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of methyl transferase from methanosarcina2 mazei
63c3e7pA_



not modelled 97.7 14 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of of putative methyltransferase from bacteroides2 vulgatus atcc 8482
64c3mb5A_



not modelled 97.7 18 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of p. abyssi trna m1a58 methyltransferase in complex2 with s-adenosyl-l-methionine
65d2b9ea1



not modelled 97.7 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:NOL1/NOP2/sun
66d2o57a1



not modelled 97.7 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
67c3fuxB_



not modelled 97.7 15 PDB header:transferase
Chain: B: PDB Molecule:dimethyladenosine transferase;
PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121
68c3ofkA_



not modelled 97.7 15 PDB header:transferase
Chain: A: PDB Molecule:nodulation protein s;
PDBTitle: crystal structure of n-methyltransferase nods from bradyrhizobium2 japonicum wm9 in complex with s-adenosyl-l-homocysteine (sah)
69c3ku1E_



not modelled 97.6 14 PDB header:transferase
Chain: E: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of streptococcus pneumoniae sp1610, a2 putative trna (m1a22) methyltransferase, in complex with s-3 adenosyl-l-methionine
70c3e23A_



not modelled 97.6 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein rpa2492;
PDBTitle: crystal structure of the rpa2492 protein in complex with2 sam from rhodopseudomonas palustris, northeast structural3 genomics consortium target rpr299
71c3grzA_



not modelled 97.6 16 PDB header:transferase
Chain: A: PDB Molecule:ribosomal protein l11 methyltransferase;
PDBTitle: crystal structure of ribosomal protein l11 methylase from2 lactobacillus delbrueckii subsp. bulgaricus
72c3cc8A_



not modelled 97.6 13 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a putative methyltransferase (bce_1332) from2 bacillus cereus atcc 10987 at 1.64 a resolution
73d1yuba_



not modelled 97.6 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
74d1nkva_



not modelled 97.6 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Hypothetical Protein YjhP
75d1wxxa2



not modelled 97.6 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:hypothetical RNA methyltransferase
76d1oria_



not modelled 97.6 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
77c1wxwA_



not modelled 97.6 19 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein ttha1280;
PDBTitle: crystal structure of tt1595, a putative sam-dependent2 methyltransferase from thermus thermophillus hb8
78d2avna1



not modelled 97.6 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
79c3ccfB_



not modelled 97.6 20 PDB header:transferase
Chain: B: PDB Molecule:cyclopropane-fatty-acyl-phospholipid synthase;
PDBTitle: crystal structure of putative methyltransferase (yp_321342.1) from2 anabaena variabilis atcc 29413 at 1.90 a resolution
80c3lbfC_



not modelled 97.6 19 PDB header:transferase
Chain: C: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: crystal structure of protein l-isoaspartyl methyltransferase from2 escherichia coli
81d1m6ya2



not modelled 97.6 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:MraW-like putative methyltransferases
82c3a27A_



not modelled 97.6 17 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein mj1557;
PDBTitle: crystal structure of m. jannaschii tyw2 in complex with2 adomet
83c3gnlB_



not modelled 97.6 11 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:uncharacterized protein, duf633, lmof2365_1472;
PDBTitle: structure of uncharacterized protein (lmof2365_1472) from2 listeria monocytogenes serotype 4b
84d2fpoa1



not modelled 97.5 11 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
85c1orhA_



not modelled 97.5 10 PDB header:transferase
Chain: A: PDB Molecule:protein arginine n-methyltransferase 1;
PDBTitle: structure of the predominant protein arginine methyltransferase prmt1
86d1f3la_



not modelled 97.5 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Arginine methyltransferase
87d1zq9a1



not modelled 97.5 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:rRNA adenine dimethylase-like
88d1uwva2



not modelled 97.5 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:(Uracil-5-)-methyltransferase
89c3m70A_



not modelled 97.5 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:tellurite resistance protein tehb homolog;
PDBTitle: crystal structure of tehb from haemophilus influenzae
90c3f4kA_



not modelled 97.5 12 PDB header:transferase
Chain: A: PDB Molecule:putative methyltransferase;
PDBTitle: crystal structure of a probable methyltransferase from2 bacteroides thetaiotaomicron. northeast structural3 genomics target btr309.
91d2p7ia1



not modelled 97.5 13 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:UbiE/COQ5-like
92d2esra1



not modelled 97.5 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:YhhF-like
93d1pjza_



not modelled 97.5 6 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Thiopurine S-methyltransferase
94d1xdza_



not modelled 97.5 14 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Glucose-inhibited division protein B (GidB)
95d1l1ea_



not modelled 97.5 17 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
96c3g5tA_



not modelled 97.5 16 PDB header:transferase
Chain: A: PDB Molecule:trans-aconitate 3-methyltransferase;
PDBTitle: crystal structure of trans-aconitate 3-methyltransferase2 from yeast
97c2pwyB_



not modelled 97.5 16 PDB header:transferase
Chain: B: PDB Molecule:trna (adenine-n(1)-)-methyltransferase;
PDBTitle: crystal structure of a m1a58 trna methyltransferase
98c3egiA_



not modelled 97.5 16 PDB header:transferase
Chain: A: PDB Molecule:trimethylguanosine synthase homolog;
PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase tgs1 bound to m7gpppa (inactive form)
99c1sqgA_



not modelled 97.5 24 PDB header:transferase
Chain: A: PDB Molecule:sun protein;
PDBTitle: the crystal structure of the e. coli fmu apoenzyme at 1.652 a resolution
100c3dliB_



not modelled 97.4 7 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of a sam dependent methyltransferase from2 archaeoglobus fulgidus
101c2ozvA_



not modelled 97.4 13 PDB header:transferase
Chain: A: PDB Molecule:hypothetical protein atu0636;
PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens.
102c3l8dA_



not modelled 97.4 14 PDB header:transferase
Chain: A: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of methyltransferase from bacillus2 thuringiensis
103c2yxeB_



not modelled 97.4 15 PDB header:transferase
Chain: B: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: crystal structure of l-isoaspartyl protein carboxyl methyltranferase
104c1wg8B_



not modelled 97.4 16 PDB header:transferase
Chain: B: PDB Molecule:predicted s-adenosylmethionine-dependent
PDBTitle: crystal structure of a predicted s-adenosylmethionine-2 dependent methyltransferase tt1512 from thermus3 thermophilus hb8.
105d1i1na_



not modelled 97.4 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Protein-L-isoaspartyl O-methyltransferase
106d1o54a_



not modelled 97.4 16 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
107c2yvlB_



not modelled 97.4 10 PDB header:transferase
Chain: B: PDB Molecule:hypothetical protein;
PDBTitle: crystal structure of trna (m1a58) methyltransferase trmi from aquifex2 aeolicus
108c3a26A_



not modelled 97.4 12 PDB header:transferase
Chain: A: PDB Molecule:uncharacterized protein ph0793;
PDBTitle: crystal structure of p. horikoshii tyw2 in complex with2 mesado
109c3b3jA_



not modelled 97.4 13 PDB header:transferase
Chain: A: PDB Molecule:histone-arginine methyltransferase carm1;
PDBTitle: the 2.55 a crystal structure of the apo catalytic domain of2 coactivator-associated arginine methyl transferase i(carm1:28-507,3 residues 28-146 and 479-507 not ordered)
110d1wy7a1



not modelled 97.4 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Ta1320-like
111d1xtpa_



not modelled 97.4 15 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:AD-003 protein-like
112c1dl5A_



not modelled 97.4 17 PDB header:transferase
Chain: A: PDB Molecule:protein-l-isoaspartate o-methyltransferase;
PDBTitle: protein-l-isoaspartate o-methyltransferase
113c3busB_



not modelled 97.4 14 PDB header:transferase
Chain: B: PDB Molecule:methyltransferase;
PDBTitle: crystal structure of rebm
114c1yb2A_



not modelled 97.4 18 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ta0852;
PDBTitle: structure of a putative methyltransferase from thermoplasma2 acidophilum.
115d1yb2a1



not modelled 97.4 18 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:tRNA(1-methyladenosine) methyltransferase-like
116c3mq2A_



not modelled 97.4 14 PDB header:transferase
Chain: A: PDB Molecule:16s rrna methyltransferase;
PDBTitle: crystal structure of 16s rrna methyltranferase kamb
117d1kpia_



not modelled 97.4 19 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Mycolic acid cyclopropane synthase
118d2frna1



not modelled 97.4 10 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:Met-10+ protein-like
119c3ggdA_



not modelled 97.3 14 PDB header:transferase
Chain: A: PDB Molecule:sam-dependent methyltransferase;
PDBTitle: crystal structure of sam-dependent methyltransferase (yp_325210.1)2 from anabaena variabilis atcc 29413 at 2.11 a resolution
120d2b3ta1



not modelled 97.3 20 Fold:S-adenosyl-L-methionine-dependent methyltransferases
Superfamily:S-adenosyl-L-methionine-dependent methyltransferases
Family:N5-glutamine methyltransferase, HemK

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0