Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP06960
DateThu Jan 5 10:59:30 GMT 2012
Unique Job ID9f4e76347dbc4c26

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2otcA_
Top template information
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine
Confidence and coverage
Confidence:100.0% Coverage:100%
333 residues (100% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSDLYKKHFLKLLDFTPAQFTSLLTLAAQLKADKKNGKEVQKLTGKNIALIFEKDSTRTR
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Disorder  ??????


























??????




















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   .........70.........80.........90.........100.........110.........120
Sequence  CSFEVAAFDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGHGQEVVETLAQY
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????????
































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   .........130.........140.........150.........160.........170.........180
Sequence  AGVPVWNGLTNEFHPTQLLADLMTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALT
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   .........190.........200.........210.........220.........230.........240
Sequence  GLDLRLLAPKACWPEESLVAECSALAEKHGGKITLTEDVAAGVKGADFIYTDVWVSMGEA
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??
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   .........250.........260.........270.........280.........290.........300
Sequence  KEKWAERIALLRGYQVNAQMMALTDNPNVKFLHCLPAFHDDQTTLGKQMAKEFDLHGGME
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Disorder  ???




































?????
?

????






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   .........310.........320.........330....
Sequence  VTDEVFESAASIVFDQAENRMHTIKAVMMATLGE
Secondary structure 







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???
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2otc chain A

3D model

Region: 2 - 334
Aligned: 333
Modelled: 333
Confidence: 100.0%
Identity: 88%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine

Phyre2

PDB 3upd chain A

3D model

Region: 2 - 333
Aligned: 331
Modelled: 332
Confidence: 100.0%
Identity: 67%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus

Phyre2

PDB 1ort chain D

3D model

Region: 3 - 334
Aligned: 331
Modelled: 332
Confidence: 100.0%
Identity: 58%
PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa

Phyre2

PDB 2w37 chain A

3D model

Region: 2 - 334
Aligned: 328
Modelled: 333
Confidence: 100.0%
Identity: 48%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii

Phyre2

PDB 1a1s chain A

3D model

Region: 3 - 334
Aligned: 309
Modelled: 314
Confidence: 100.0%
Identity: 42%
PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus

Phyre2

PDB 1vlv chain A

3D model

Region: 2 - 332
Aligned: 300
Modelled: 313
Confidence: 100.0%
Identity: 46%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution

Phyre2

PDB 1fvo chain B

3D model

Region: 3 - 334
Aligned: 308
Modelled: 313
Confidence: 100.0%
Identity: 39%
PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate

Phyre2

PDB 1ml4 chain A

3D model

Region: 3 - 334
Aligned: 303
Modelled: 312
Confidence: 100.0%
Identity: 27%
PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi

Phyre2

PDB 2p2g chain D

3D model

Region: 7 - 334
Aligned: 292
Modelled: 297
Confidence: 100.0%
Identity: 40%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form

Phyre2

PDB 1zq2 chain A

3D model

Region: 7 - 332
Aligned: 301
Modelled: 304
Confidence: 100.0%
Identity: 36%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp

Phyre2

PDB 3tpf chain F

3D model

Region: 6 - 334
Aligned: 296
Modelled: 306
Confidence: 100.0%
Identity: 37%
PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168

Phyre2

PDB 1tug chain A domain 1

3D model

Region: 2 - 334
Aligned: 299
Modelled: 313
Confidence: 100.0%
Identity: 27%
Fold: ATC-like
Superfamily: Aspartate/ornithine carbamoyltransferase
Family: Aspartate/ornithine carbamoyltransferase

Phyre2

PDB 3grf chain A

3D model

Region: 5 - 334
Aligned: 290
Modelled: 312
Confidence: 100.0%
Identity: 33%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia

Phyre2

PDB 3sds chain A

3D model

Region: 5 - 332
Aligned: 296
Modelled: 306
Confidence: 100.0%
Identity: 34%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis

Phyre2

PDB 1pg5 chain A

3D model

Region: 7 - 334
Aligned: 288
Modelled: 308
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius

Phyre2

PDB 2rgw chain D

3D model

Region: 7 - 334
Aligned: 294
Modelled: 308
Confidence: 100.0%
Identity: 23%
PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase

Phyre2

PDB 2ef0 chain A

3D model

Region: 5 - 332
Aligned: 285
Modelled: 301
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus

Phyre2

PDB 3gd5 chain D

3D model

Region: 3 - 333
Aligned: 285
Modelled: 309
Confidence: 100.0%
Identity: 42%
PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus

Phyre2

PDB 1js1 chain Z

3D model

Region: 7 - 333
Aligned: 288
Modelled: 298
Confidence: 100.0%
Identity: 30%
PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution

Phyre2

PDB 3q98 chain A

3D model

Region: 1 - 334
Aligned: 303
Modelled: 309
Confidence: 100.0%
Identity: 24%
PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli

Phyre2
1

c2otcA_
2

c3updA_
3

c1ortD_
4

c2w37A_
5

c1a1sA_
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c1vlvA_
7

c1fvoB_
8

c1ml4A_
9

c2p2gD_
10

c1zq2A_
11

c3tpfF_
12

d1tuga1
13

c3grfA_
14

c3sdsA_
15

c1pg5A_
16

c2rgwD_
17

c2ef0A_
18

c3gd5D_
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c1js1Z_
20

c3q98A_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2otcA_



100.0 88 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine transcarbamoylase complexed with n-2 (phosphonacetyl)-l-ornithine
2c3updA_



100.0 67 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: 2.9 angstrom crystal structure of ornithine carbamoyltransferase2 (argf) from vibrio vulnificus
3c1ortD_



100.0 58 PDB header:transferase
Chain: D: PDB Molecule:ornithine transcarbamoylase;
PDBTitle: ornithine transcarbamoylase from pseudomonas aeruginosa
4c2w37A_



100.0 48 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, catabolic;
PDBTitle: crystal structure of the hexameric catabolic ornithine2 transcarbamylase from lactobacillus hilgardii
5c1a1sA_



100.0 42 PDB header:transcarbamylase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: ornithine carbamoyltransferase from pyrococcus furiosus
6c1vlvA_



100.0 46 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase (tm1097) from2 thermotoga maritima at 2.25 a resolution
7c1fvoB_



100.0 39 PDB header:transferase
Chain: B: PDB Molecule:ornithine transcarbamylase;
PDBTitle: crystal structure of human ornithine transcarbamylase complexed with2 carbamoyl phosphate
8c1ml4A_



100.0 27 PDB header:transferase
Chain: A: PDB Molecule:aspartate transcarbamoylase;
PDBTitle: the pala-liganded aspartate transcarbamoylase catalytic subunit from2 pyrococcus abyssi
9c2p2gD_



100.0 40 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from mycobacterium2 tuberculosis (rv1656): orthorhombic form
10c1zq2A_



100.0 36 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of n-acetyl-l-ornithine transcarbamylase2 complexed with cp
11c3tpfF_



100.0 37 PDB header:transferase
Chain: F: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of anabolic ornithine carbamoyltransferase from2 campylobacter jejuni subsp. jejuni nctc 11168
12d1tuga1



100.0 27 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
13c3grfA_



100.0 33 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: x-ray structure of ornithine transcarbamoylase from giardia2 lamblia
14c3sdsA_



100.0 34 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase, mitochondrial;
PDBTitle: crystal structure of a mitochondrial ornithine carbamoyltransferase2 from coccidioides immitis
15c1pg5A_



100.0 23 PDB header:transferase
Chain: A: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of the unligated (t-state) aspartate2 transcarbamoylase from the extremely thermophilic archaeon sulfolobus3 acidocaldarius
16c2rgwD_



100.0 23 PDB header:transferase
Chain: D: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: catalytic subunit of m. jannaschii aspartate2 transcarbamoylase
17c2ef0A_



100.0 42 PDB header:transferase
Chain: A: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from thermus2 thermophilus
18c3gd5D_



100.0 42 PDB header:transferase
Chain: D: PDB Molecule:ornithine carbamoyltransferase;
PDBTitle: crystal structure of ornithine carbamoyltransferase from gloeobacter2 violaceus
19c1js1Z_



100.0 30 PDB header:transferase
Chain: Z: PDB Molecule:transcarbamylase;
PDBTitle: crystal structure of a new transcarbamylase from the2 anaerobic bacterium bacteroides fragilis at 2.0 a3 resolution
20c3q98A_



100.0 24 PDB header:transferase
Chain: A: PDB Molecule:transcarbamylase;
PDBTitle: structure of ygew encoded protein from e. coli
21c3d6nB_



not modelled 100.0 22 PDB header:hydrolase/transferase
Chain: B: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: crystal structure of aquifex dihydroorotase activated by aspartate2 transcarbamoylase
22c2at2B_



not modelled 100.0 28 PDB header:
PDB COMPND:
23c3lxmC_



not modelled 100.0 31 PDB header:transferase
Chain: C: PDB Molecule:aspartate carbamoyltransferase;
PDBTitle: 2.00 angstrom resolution crystal structure of a catalytic2 subunit of an aspartate carbamoyltransferase (pyrb) from3 yersinia pestis co92
24d1duvg2



not modelled 100.0 87 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
25d1dxha2



not modelled 100.0 55 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
26d1duvg1



not modelled 100.0 89 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
27d1pvva1



not modelled 100.0 43 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
28d1vlva1



not modelled 100.0 49 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
29d1dxha1



not modelled 100.0 62 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
30d1ml4a1



not modelled 100.0 31 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
31d1otha1



not modelled 100.0 40 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
32d1ekxa1



not modelled 100.0 35 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
33d1otha2



not modelled 100.0 38 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
34d1pvva2



not modelled 100.0 40 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
35d1pg5a1



not modelled 100.0 30 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
36d2at2a1



not modelled 100.0 36 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
37d1vlva2



not modelled 100.0 43 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
38d1js1x1



not modelled 100.0 29 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
39d1ml4a2



not modelled 100.0 23 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
40d1ekxa2



not modelled 100.0 19 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
41d1pg5a2



not modelled 100.0 17 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
42d1js1x2



not modelled 100.0 30 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
43d2at2a2



not modelled 100.0 21 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
44d2atca2



not modelled 100.0 20 Fold:ATC-like
Superfamily:Aspartate/ornithine carbamoyltransferase
Family:Aspartate/ornithine carbamoyltransferase
45c3oneA_



not modelled 98.4 19 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
46c3gvpB_



not modelled 98.3 17 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
47c1d4fD_



not modelled 98.2 13 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase
48c3n58D_



not modelled 98.2 16 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
49c3dhyC_



not modelled 98.0 21 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
50c1xdwA_



not modelled 98.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:nad+-dependent (r)-2-hydroxyglutarate
PDBTitle: nad+-dependent (r)-2-hydroxyglutarate dehydrogenase from2 acidaminococcus fermentans
51c3d4oA_



not modelled 98.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
52c1v8bA_



not modelled 97.9 15 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
53c2j6iC_



not modelled 97.8 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:formate dehydrogenase;
PDBTitle: candida boidinii formate dehydrogenase (fdh) c-terminal2 mutant
54c3n7uD_



not modelled 97.7 18 PDB header:oxidoreductase
Chain: D: PDB Molecule:formate dehydrogenase;
PDBTitle: nad-dependent formate dehydrogenase from higher-plant arabidopsis2 thaliana in complex with nad and azide
55c3l07B_



not modelled 97.7 14 PDB header:oxidoreductase,hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate2 cyclohydrolase, putative bifunctional protein fold from francisella3 tularensis.
56c3d64A_



not modelled 97.7 19 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
57c1ybaC_



not modelled 97.6 17 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: the active form of phosphoglycerate dehydrogenase
58c3k5pA_



not modelled 97.6 19 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of amino acid-binding act: d-isomer specific 2-2 hydroxyacid dehydrogenase catalytic domain from brucella melitensis
59c4a26B_



not modelled 97.6 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative c-1-tetrahydrofolate synthase, cytoplasmic;
PDBTitle: the crystal structure of leishmania major n5,n10-2 methylenetetrahydrofolate dehydrogenase/cyclohydrolase
60c2gcgB_



not modelled 97.5 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate reductase/hydroxypyruvate reductase;
PDBTitle: ternary crystal structure of human glyoxylate2 reductase/hydroxypyruvate reductase
61c2dbqA_



not modelled 97.4 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:glyoxylate reductase;
PDBTitle: crystal structure of glyoxylate reductase (ph0597) from pyrococcus2 horikoshii ot3, complexed with nadp (i41)
62c2nacA_



not modelled 97.4 13 PDB header:oxidoreductase(aldehyde(d),nad+(a))
Chain: A: PDB Molecule:nad-dependent formate dehydrogenase;
PDBTitle: high resolution structures of holo and apo formate dehydrogenase
63c2rirA_



not modelled 97.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
64d1mx3a1



not modelled 97.4 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
65c2omeA_



not modelled 97.4 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:c-terminal-binding protein 2;
PDBTitle: crystal structure of human ctbp2 dehydrogenase complexed with nad(h)
66c1b0aA_



not modelled 97.3 15 PDB header:oxidoreductase,hydrolase
Chain: A: PDB Molecule:protein (fold bifunctional protein);
PDBTitle: 5,10, methylene-tetrahydropholate2 dehydrogenase/cyclohydrolase from e coli.
67c3evtA_



not modelled 97.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from2 lactobacillus plantarum
68c1gdhA_



not modelled 97.3 18 PDB header:oxidoreductase(choh (d)-nad(p)+ (a))
Chain: A: PDB Molecule:d-glycerate dehydrogenase;
PDBTitle: crystal structure of a nad-dependent d-glycerate2 dehydrogenase at 2.4 angstroms resolution
69c2eklA_



not modelled 97.2 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: structure of st1218 protein from sulfolobus tokodaii
70c3oetF_



not modelled 97.2 15 PDB header:oxidoreductase
Chain: F: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: d-erythronate-4-phosphate dehydrogenase complexed with nad
71c2o4cB_



not modelled 97.2 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:erythronate-4-phosphate dehydrogenase;
PDBTitle: crystal structure of d-erythronate-4-phosphate dehydrogenase complexed2 with nad
72c1gpjA_



not modelled 97.2 14 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri
73c3gg9C_



not modelled 97.1 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-3-phosphoglycerate dehydrogenase oxidoreductase protein;
PDBTitle: crystal structure of putative d-3-phosphoglycerate dehydrogenase2 oxidoreductase from ralstonia solanacearum
74c1dxyA_



not modelled 97.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-2-hydroxyisocaproate dehydrogenase;
PDBTitle: structure of d-2-hydroxyisocaproate dehydrogenase
75c1j4aA_



not modelled 97.1 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: insights into domain closure, substrate specificity and2 catalysis of d-lactate dehydrogenase from lactobacillus3 bulgaricus
76c3bazA_



not modelled 97.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:hydroxyphenylpyruvate reductase;
PDBTitle: structure of hydroxyphenylpyruvate reductase from coleus blumei in2 complex with nadp+
77c1qp8A_



not modelled 97.1 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:formate dehydrogenase;
PDBTitle: crystal structure of a putative formate dehydrogenase from2 pyrobaculum aerophilum
78c3hg7A_



not modelled 97.0 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-isomer specific 2-hydroxyacid dehydrogenase family
PDBTitle: crystal structure of d-isomer specific 2-hydroxyacid dehydrogenase2 family protein from aeromonas salmonicida subsp. salmonicida a449
79d1gpja2



not modelled 97.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
80d1qp8a1



not modelled 97.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
81c2pi1C_



not modelled 96.9 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:d-lactate dehydrogenase;
PDBTitle: crystal structure of d-lactate dehydrogenase from aquifex2 aeolicus complexed with nad and lactic acid
82d1gdha1



not modelled 96.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
83c3kboB_



not modelled 96.9 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glyoxylate/hydroxypyruvate reductase a;
PDBTitle: 2.14 angstrom crystal structure of putative oxidoreductase (ycdw) from2 salmonella typhimurium in complex with nadp
84c2cukC_



not modelled 96.9 20 PDB header:oxidoreductase
Chain: C: PDB Molecule:glycerate dehydrogenase/glyoxylate reductase;
PDBTitle: crystal structure of tt0316 protein from thermus thermophilus hb8
85c2w2kB_



not modelled 96.9 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:d-mandelate dehydrogenase;
PDBTitle: crystal structure of the apo forms of rhodotorula graminis2 d-mandelate dehydrogenase at 1.8a.
86c3gvxA_



not modelled 96.8 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:glycerate dehydrogenase related protein;
PDBTitle: crystal structure of glycerate dehydrogenase related2 protein from thermoplasma acidophilum
87d2naca1



not modelled 96.8 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
88d2dlda1



not modelled 96.8 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
89d1sc6a1



not modelled 96.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
90d1a4ia1



not modelled 96.8 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
91c3p2oB_



not modelled 96.8 17 PDB header:oxidoreductase, hydrolase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
92c2g76A_



not modelled 96.7 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
93c1wwkA_



not modelled 96.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of phosphoglycerate dehydrogenase from pyrococcus2 horikoshii ot3
94c1ygyA_



not modelled 96.6 24 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of d-3-phosphoglycerate dehydrogenase from2 mycobacterium tuberculosis
95d1b0aa1



not modelled 96.6 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
96c4a5oB_



not modelled 96.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of pseudomonas aeruginosa n5, n10-2 methylenetetrahydrofolate dehydrogenase-cyclohydrolase (fold)
97d1j4aa1



not modelled 96.5 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
98c3nglA_



not modelled 96.5 12 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of bifunctional 5,10-methylenetetrahydrofolate2 dehydrogenase / cyclohydrolase from thermoplasma acidophilum
99d1li4a1



not modelled 96.5 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
100d1pjca1



not modelled 96.4 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
101d1dxya1



not modelled 96.3 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
102c3p2oA_



not modelled 96.3 18 PDB header:oxidoreductase, hydrolase
Chain: A: PDB Molecule:bifunctional protein fold;
PDBTitle: crystal structure of fold bifunctional protein from campylobacter2 jejuni
103c3g79A_



not modelled 96.3 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:ndp-n-acetyl-d-galactosaminuronic acid dehydrogenase;
PDBTitle: crystal structure of ndp-n-acetyl-d-galactosaminuronic acid2 dehydrogenase from methanosarcina mazei go1
104d1ygya1



not modelled 96.3 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
105c1u8xX_



not modelled 96.1 16 PDB header:hydrolase
Chain: X: PDB Molecule:maltose-6'-phosphate glucosidase;
PDBTitle: crystal structure of glva from bacillus subtilis, a metal-requiring,2 nad-dependent 6-phospho-alpha-glucosidase
106c1vjtA_



not modelled 96.1 22 PDB header:hydrolase
Chain: A: PDB Molecule:alpha-glucosidase;
PDBTitle: crystal structure of alpha-glucosidase (tm0752) from thermotoga2 maritima at 2.50 a resolution
107d1v8ba1



not modelled 96.0 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
108c3gg2B_



not modelled 95.8 23 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
109c1l7eC_



not modelled 95.7 18 PDB header:oxidoreductase
Chain: C: PDB Molecule:nicotinamide nucleotide transhydrogenase,
PDBTitle: crystal structure of r. rubrum transhydrogenase domain i2 with bound nadh
110d1vjta1



not modelled 95.5 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
111d1l7da1



not modelled 95.5 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
112c2d0iC_



not modelled 95.4 10 PDB header:oxidoreductase
Chain: C: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure ph0520 protein from pyrococcus horikoshii ot3
113c3oj0A_



not modelled 95.4 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: crystal structure of glutamyl-trna reductase from thermoplasma2 volcanium (nucleotide binding domain)
114c2y0dB_



not modelled 95.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
115c1s6yA_



not modelled 95.3 22 PDB header:hydrolase
Chain: A: PDB Molecule:6-phospho-beta-glucosidase;
PDBTitle: 2.3a crystal structure of phospho-beta-glucosidase
116c1a4iB_



not modelled 94.9 19 PDB header:oxidoreductase
Chain: B: PDB Molecule:methylenetetrahydrofolate dehydrogenase /
PDBTitle: human tetrahydrofolate dehydrogenase / cyclohydrolase
117c1obbB_



not modelled 94.9 18 PDB header:hydrolase
Chain: B: PDB Molecule:alpha-glucosidase;
PDBTitle: alpha-glucosidase a, agla, from thermotoga maritima in2 complex with maltose and nad+
118c2eezG_



not modelled 94.9 20 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
119d1civa1



not modelled 94.8 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
120c7mdhA_



not modelled 94.8 17 PDB header:chloroplastic malate dehydrogenase
Chain: A: PDB Molecule:protein (malate dehydrogenase);
PDBTitle: structural basis for light acitvation of a chloroplast enzyme. the2 structure of sorghum nadp-malate dehydrogenase in its oxidized form

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
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Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0