Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	T	L	T	A	R	P	E	A	I	T	F	D	P	Q	Q	S	A	L	I	V	V	D	M	Q	N	A	Y	A	T	P	G	G	Y	L	D	L	A	G	F	D	V	S	T	T	R	P	V	I	A	N	I	Q	T	A	V	T	A	A
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	A	A	G	M	L	I	I	W	F	Q	N	G	W	D	E	Q	Y	V	E	A	G	G	P	G	S	P	N	F	H	K	S	N	A	L	K	T	M	R	K	Q	P	Q	L	Q	G	K	L	L	A	K	G	S	W	D	Y	Q	L	V	D
Secondary structure
SS confidence
Disorder																						?			?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		E	L	V	P	Q	P	G	D	I	V	L	P	K	P	R	Y	S	G	F	F	N	T	P	L	D	S	I	L	R	S	R	G	I	R	H	L	V	F	T	G	I	A	T	N	V	C	V	E	S	T	L	R	D	G	F	F	L	E	Y	F
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Sequence		G	V	V	L	E	D	A	T	H	Q	A	G	P	K	F	A	Q	K	A	A	L	F	N	I	E	T	F	F	G	W	V	S	D	V	E	T	F	C	D	A	L	S	P	T	S	F	A	H	I	A
Secondary structure
SS confidence
Disorder																																													?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1nba chain A Region: 15 - 225 Aligned: 194 Modelled: 200 Confidence: 100.0% Identity: 25% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 2fq1 chain A Region: 4 - 218 Aligned: 191 Modelled: 198 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains Phyre2 PDB 3kl2 chain K Region: 12 - 222 Aligned: 199 Modelled: 200 Confidence: 100.0% Identity: 32% PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis Phyre2 PDB 3irv chain A Region: 4 - 223 Aligned: 201 Modelled: 206 Confidence: 100.0% Identity: 33% PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a Phyre2 PDB 1nf9 chain A Region: 4 - 219 Aligned: 190 Modelled: 199 Confidence: 100.0% Identity: 24% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 1j2r chain A Region: 11 - 221 Aligned: 187 Modelled: 187 Confidence: 100.0% Identity: 28% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3oqp chain A Region: 17 - 230 Aligned: 180 Modelled: 179 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3oqp chain B Region: 17 - 228 Aligned: 178 Modelled: 184 Confidence: 100.0% Identity: 29% PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution Phyre2 PDB 3hu5 chain B Region: 16 - 223 Aligned: 189 Modelled: 195 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough Phyre2 PDB 3mcw chain A Region: 10 - 227 Aligned: 183 Modelled: 183 Confidence: 100.0% Identity: 25% PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution Phyre2 PDB 3ot4 chain F Region: 5 - 219 Aligned: 192 Modelled: 194 Confidence: 100.0% Identity: 21% PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf Phyre2 PDB 3hb7 chain G Region: 16 - 222 Aligned: 182 Modelled: 189 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a Phyre2 PDB 2wta chain A Region: 11 - 219 Aligned: 198 Modelled: 209 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease Phyre2 PDB 3eef chain A Region: 16 - 218 Aligned: 172 Modelled: 181 Confidence: 100.0% Identity: 27% PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum Phyre2 PDB 3r2j chain C Region: 11 - 218 Aligned: 183 Modelled: 191 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate Phyre2 PDB 1im5 chain A Region: 17 - 212 Aligned: 172 Modelled: 179 Confidence: 100.0% Identity: 26% Fold: Isochorismatase-like hydrolases Superfamily: Isochorismatase-like hydrolases Family: Isochorismatase-like hydrolases Phyre2 PDB 3lqy chain A Region: 12 - 219 Aligned: 175 Modelled: 179 Confidence: 100.0% Identity: 20% PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica Phyre2 PDB 3o93 chain A Region: 17 - 217 Aligned: 177 Modelled: 183 Confidence: 100.0% Identity: 23% PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes Phyre2 PDB 2a67 chain C Region: 16 - 213 Aligned: 159 Modelled: 166 Confidence: 100.0% Identity: 24% PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein Phyre2 PDB 3gbc chain A Region: 19 - 214 Aligned: 174 Modelled: 181 Confidence: 100.0% Identity: 26% PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide Phyre2 1 d1nbaa_ 2 c2fq1A_ 3 c3kl2K_ 4 c3irvA_ 5 d1nf9a_ 6 d1j2ra_ 7 c3oqpA_ 8 c3oqpB_ 9 c3hu5B_ 10 c3mcwA_ 11 c3ot4F_ 12 c3hb7G_ 13 c2wtaA_ 14 c3eefA_ 15 c3r2jC_ 16 d1im5a_ 17 c3lqyA_ 18 c3o93A_ 19 c2a67C_ 20 c3gbcA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1nbaa_ 100.0 25 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 2 c2fq1A_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:isochorismatase; PDBTitle: crystal structure of the two-domain non-ribosomal peptide synthetase2 entb containing isochorismate lyase and aryl-carrier protein domains 3 c3kl2K_ 100.0 32 PDB header:structural genomics, unknown function Chain: K: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase from streptomyces2 avermitilis 4 c3irvA_ 100.0 33 PDB header:hydrolase Chain: A: PDB Molecule:cysteine hydrolase; PDBTitle: crystal structure of cysteine hydrolase pspph_2384 from pseudomonas2 syringae pv. phaseolicola 1448a 5 d1nf9a_ 100.0 24 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 6 d1j2ra_ 100.0 28 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 7 c3oqpA_ 100.0 29 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 8 c3oqpB_ 100.0 29 PDB header:hydrolase Chain: B: PDB Molecule:putative isochorismatase; PDBTitle: crystal structure of a putative isochorismatase (bxe_a0706) from2 burkholderia xenovorans lb400 at 1.22 a resolution 9 c3hu5B_ 100.0 26 PDB header:hydrolase Chain: B: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein from desulfovibrio2 vulgaris subsp. vulgaris str. hildenborough 10 c3mcwA_ 100.0 25 PDB header:hydrolase Chain: A: PDB Molecule:putative hydrolase; PDBTitle: crystal structure of an a putative hydrolase of the isochorismatase2 family (cv_1320) from chromobacterium violaceum atcc 12472 at 1.06 a3 resolution 11 c3ot4F_ 100.0 21 PDB header:hydrolase Chain: F: PDB Molecule:putative isochorismatase; PDBTitle: structure and catalytic mechanism of bordetella bronchiseptica nicf 12 c3hb7G_ 100.0 26 PDB header:hydrolase Chain: G: PDB Molecule:isochorismatase hydrolase; PDBTitle: the crystal structure of an isochorismatase-like hydrolase from2 alkaliphilus metalliredigens to 2.3a 13 c2wtaA_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: acinetobacter baumanii nicotinamidase pyrazinamidease 14 c3eefA_ 100.0 27 PDB header:hydrolase Chain: A: PDB Molecule:n-carbamoylsarcosine amidase related protein; PDBTitle: crystal structure of n-carbamoylsarcosine amidase from thermoplasma2 acidophilum 15 c3r2jC_ 100.0 26 PDB header:hydrolase Chain: C: PDB Molecule:alpha/beta-hydrolase-like protein; PDBTitle: crystal structure of pnc1 from l. infantum in complex with nicotinate 16 d1im5a_ 100.0 26 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 17 c3lqyA_ 100.0 20 PDB header:hydrolase Chain: A: PDB Molecule:putative isochorismatase hydrolase; PDBTitle: crystal structure of putative isochorismatase hydrolase from2 oleispira antarctica 18 c3o93A_ 100.0 23 PDB header:hydrolase Chain: A: PDB Molecule:nicotinamidase; PDBTitle: high resolution crystal structures of streptococcus pneumoniae2 nicotinamidase with trapped intermediates provide insights into3 catalytic mechanism and inhibition by aldehydes 19 c2a67C_ 100.0 24 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:isochorismatase family protein; PDBTitle: crystal structure of isochorismatase family protein 20 c3gbcA_ 100.0 26 PDB header:hydrolase Chain: A: PDB Molecule:pyrazinamidase/nicotinamidas pnca; PDBTitle: determination of the crystal structure of the pyrazinamidase from2 m.tuberculosis : a structure-function analysis for prediction3 resistance to pyrazinamide 21 c2h0rD_ not modelled 100.0 22 PDB header:hydrolase Chain: D: PDB Molecule:nicotinamidase; PDBTitle: structure of the yeast nicotinamidase pnc1p 22 d1yaca_ not modelled 100.0 17 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 23 c1yzvA_ not modelled 100.0 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein; PDBTitle: hypothetical protein from trypanosoma cruzi 24 c2b34C_ not modelled 100.0 23 PDB header:hydrolase Chain: C: PDB Molecule:mar1 ribonuclease; PDBTitle: structure of mar1 ribonuclease from caenorhabditis elegans 25 d1x9ga_ not modelled 100.0 16 Fold:Isochorismatase-like hydrolases Superfamily:Isochorismatase-like hydrolases Family:Isochorismatase-like hydrolases 26 d1cmwa2 not modelled 89.7 13 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 27 c3g8rA_ not modelled 74.8 13 PDB header:biosynthetic protein Chain: A: PDB Molecule:probable spore coat polysaccharide biosynthesis protein e; PDBTitle: crystal structure of putative spore coat polysaccharide biosynthesis2 protein e from chromobacterium violaceum atcc 12472 28 c1xuzA_ not modelled 71.9 14 PDB header:biosynthetic protein Chain: A: PDB Molecule:polysialic acid capsule biosynthesis protein siac; PDBTitle: crystal structure analysis of sialic acid synthase (neub)from2 neisseria meningitidis, bound to mn2+, phosphoenolpyruvate, and n-3 acetyl mannosaminitol 29 c2ihnA_ not modelled 64.3 5 PDB header:hydrolase/dna Chain: A: PDB Molecule:ribonuclease h; PDBTitle: co-crystal of bacteriophage t4 rnase h with a fork dna2 substrate 30 d1tfra2 not modelled 64.1 2 Fold:PIN domain-like Superfamily:PIN domain-like Family:5' to 3' exonuclease catalytic domain 31 d2zdra2 not modelled 62.2 14 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 32 d1vlia2 not modelled 53.7 12 Fold:TIM beta/alpha-barrel Superfamily:Aldolase Family:NeuB-like 33 c1ddzA_ not modelled 47.7 14 PDB header:lyase Chain: A: PDB Molecule:carbonic anhydrase; PDBTitle: x-ray structure of a beta-carbonic anhydrase from the red2 alga, porphyridium purpureum r-1 34 d1a9xa3 not modelled 46.8 13 Fold:PreATP-grasp domain Superfamily:PreATP-grasp domain Family:BC N-terminal domain-like 35 d4pfka_ not modelled 46.1 16 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 36 c1vliA_ not modelled 44.1 12 PDB header:biosynthetic protein Chain: A: PDB Molecule:spore coat polysaccharide biosynthesis protein spse; PDBTitle: crystal structure of spore coat polysaccharide biosynthesis protein2 spse (bsu37870) from bacillus subtilis at 2.38 a resolution 37 c1z2iA_ not modelled 37.3 20 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of agrobacterium tumefaciens malate2 dehydrogenase, new york structural genomics consortium 38 c2nwqA_ not modelled 35.1 20 PDB header:oxidoreductase Chain: A: PDB Molecule:probable short-chain dehydrogenase; PDBTitle: short chain dehydrogenase from pseudomonas aeruginosa 39 d1tyza_ not modelled 34.8 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 40 d1xrha_ not modelled 33.0 14 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 41 d1f2da_ not modelled 32.8 15 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 42 c1vbiA_ not modelled 31.0 15 PDB header:oxidoreductase Chain: A: PDB Molecule:type 2 malate/lactate dehydrogenase; PDBTitle: crystal structure of type 2 malate/lactate dehydrogenase from thermus2 thermophilus hb8 43 d1xsea_ not modelled 30.8 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 44 c3uoeB_ not modelled 29.6 14 PDB header:oxidoreductase Chain: B: PDB Molecule:dehydrogenase; PDBTitle: the crystal structure of dehydrogenase from sinorhizobium meliloti 45 d1gz6a_ not modelled 28.6 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 46 d1rfma_ not modelled 28.4 20 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 47 d1pfka_ not modelled 27.8 18 Fold:Phosphofructokinase Superfamily:Phosphofructokinase Family:Phosphofructokinase 48 d1nxua_ not modelled 27.3 14 Fold:L-sulfolactate dehydrogenase-like Superfamily:L-sulfolactate dehydrogenase-like Family:L-sulfolactate dehydrogenase-like 49 c2b4qB_ not modelled 26.9 10 PDB header:oxidoreductase Chain: B: PDB Molecule:rhamnolipids biosynthesis 3-oxoacyl-[acyl- PDBTitle: pseudomonas aeruginosa rhlg/nadp active-site complex 50 d1qsga_ not modelled 26.5 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 51 c2ptgA_ not modelled 25.8 10 PDB header:oxidoreductase Chain: A: PDB Molecule:enoyl-acyl carrier reductase; PDBTitle: crystal structure of eimeria tenella enoyl reductase 52 c3ijrF_ not modelled 24.7 7 PDB header:oxidoreductase Chain: F: PDB Molecule:oxidoreductase, short chain dehydrogenase/reductase family; PDBTitle: 2.05 angstrom resolution crystal structure of a short chain2 dehydrogenase from bacillus anthracis str. 'ames ancestor' in complex3 with nad+ 53 c2nm0B_ not modelled 24.1 13 PDB header:oxidoreductase Chain: B: PDB Molecule:probable 3-oxacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of sco1815: a beta-ketoacyl-acyl carrier protein2 reductase from streptomyces coelicolor a3(2) 54 c1v9nA_ not modelled 23.9 18 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: structure of malate dehydrogenase from pyrococcus horikoshii ot3 55 d1mxia_ not modelled 23.7 13 Fold:alpha/beta knot Superfamily:alpha/beta knot Family:SpoU-like RNA 2'-O ribose methyltransferase 56 c2g8yB_ not modelled 23.6 14 PDB header:oxidoreductase Chain: B: PDB Molecule:malate/l-lactate dehydrogenases; PDBTitle: the structure of a putative malate/lactate dehydrogenase from e. coli. 57 d1xp8a1 not modelled 23.5 17 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 58 d1j0aa_ not modelled 23.5 17 Fold:Tryptophan synthase beta subunit-like PLP-dependent enzymes Superfamily:Tryptophan synthase beta subunit-like PLP-dependent enzymes Family:Tryptophan synthase beta subunit-like PLP-dependent enzymes 59 d1xq1a_ not modelled 23.2 7 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 60 c3eywA_ not modelled 22.8 20 PDB header:transport protein Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff 61 c2rgoA_ not modelled 22.6 11 PDB header:oxidoreductase Chain: A: PDB Molecule:alpha-glycerophosphate oxidase; PDBTitle: structure of alpha-glycerophosphate oxidase from2 streptococcus sp.: a template for the mitochondrial alpha-3 glycerophosphate dehydrogenase 62 c3toxG_ not modelled 22.1 13 PDB header:oxidoreductase Chain: G: PDB Molecule:short chain dehydrogenase; PDBTitle: crystal structure of a short chain dehydrogenase in complex with2 nad(p) from sinorhizobium meliloti 1021 63 c3fkjA_ not modelled 22.0 12 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerases; PDBTitle: crystal structure of a putative phosphosugar isomerase (stm_0572) from2 salmonella typhimurium lt2 at 2.12 a resolution 64 c3nugA_ not modelled 21.7 13 PDB header:oxidoreductase Chain: A: PDB Molecule:3-oxoacyl-(acyl-carrier protein) reductase; PDBTitle: crystal structure of wild type tetrameric pyridoxal 4-dehydrogenase2 from mesorhizobium loti 65 c1zxxA_ not modelled 21.6 21 PDB header:transferase Chain: A: PDB Molecule:6-phosphofructokinase; PDBTitle: the crystal structure of phosphofructokinase from lactobacillus2 delbrueckii 66 c2ha8A_ not modelled 21.4 12 PDB header:rna binding protein Chain: A: PDB Molecule:tar (hiv-1) rna loop binding protein; PDBTitle: methyltransferase domain of human tar (hiv-1) rna binding2 protein 1 67 d1ooea_ not modelled 20.8 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 68 c3euaD_ not modelled 20.8 11 PDB header:isomerase Chain: D: PDB Molecule:putative fructose-aminoacid-6-phosphate deglycase; PDBTitle: crystal structure of a putative phosphosugar isomerase (bsu32610) from2 bacillus subtilis at 1.90 a resolution 69 d1ddza2 not modelled 20.8 9 Fold:Resolvase-like Superfamily:beta-carbonic anhydrase, cab Family:beta-carbonic anhydrase, cab 70 c3rd5A_ not modelled 20.2 20 PDB header:oxidoreductase Chain: A: PDB Molecule:mypaa.01249.c; PDBTitle: crystal structure of a putative uncharacterized protein from2 mycobacterium paratuberculosis 71 d1ulua_ not modelled 19.9 3 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 72 d1ddza1 not modelled 19.9 16 Fold:Resolvase-like Superfamily:beta-carbonic anhydrase, cab Family:beta-carbonic anhydrase, cab 73 d1nlfa_ not modelled 19.9 18 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:RecA protein-like (ATPase-domain) 74 c3iccA_ not modelled 19.5 7 PDB header:oxidoreductase Chain: A: PDB Molecule:putative 3-oxoacyl-(acyl carrier protein) reductase; PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl carrier protein)2 reductase from bacillus anthracis at 1.87 a resolution 75 c3i0pA_ not modelled 19.5 20 PDB header:oxidoreductase Chain: A: PDB Molecule:malate dehydrogenase; PDBTitle: crystal structure of malate dehydrogenase from entamoeba histolytica 76 c3grkE_ not modelled 19.3 10 PDB header:oxidoreductase Chain: E: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of short chain dehydrogenase reductase2 sdr glucose-ribitol dehydrogenase from brucella melitensis 77 c1wtjB_ not modelled 19.3 22 PDB header:oxidoreductase Chain: B: PDB Molecule:ureidoglycolate dehydrogenase; PDBTitle: crystal structure of delta1-piperideine-2-carboxylate2 reductase from pseudomonas syringae pvar.tomato 78 c1cmwA_ not modelled 19.0 13 PDB header:transferase Chain: A: PDB Molecule:protein (dna polymerase i); PDBTitle: crystal structure of taq dna-polymerase shows a new2 orientation for the structure-specific nuclease domain 79 c3g68A_ not modelled 18.9 16 PDB header:isomerase Chain: A: PDB Molecule:putative phosphosugar isomerase; PDBTitle: crystal structure of a putative phosphosugar isomerase (cd3275) from2 clostridium difficile 630 at 1.80 a resolution 80 d1k2wa_ not modelled 17.9 10 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 81 c3tfoD_ not modelled 17.6 13 PDB header:oxidoreductase Chain: D: PDB Molecule:putative 3-oxoacyl-(acyl-carrier-protein) reductase; PDBTitle: crystal structure of a putative 3-oxoacyl-(acyl-carrier-protein)2 reductase from sinorhizobium meliloti 82 c1f8sA_ not modelled 17.3 22 PDB header:oxidoreductase Chain: A: PDB Molecule:l-amino acid oxidase; PDBTitle: crystal structure of l-amino acid oxidase from calloselasma2 rhodostoma, complexed with three molecules of o-aminobenzoate. 83 d1mg5a_ not modelled 17.3 13 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 84 c2cfcB_ not modelled 17.3 13 PDB header:oxidoreductase Chain: B: PDB Molecule:2-(r)-hydroxypropyl-com dehydrogenase; PDBTitle: structural basis for stereo selectivity in the (r)- and2 (s)-hydroxypropylethane thiosulfonate dehydrogenases 85 d1xg5a_ not modelled 16.9 17 Fold:NAD(P)-binding Rossmann-fold domains Superfamily:NAD(P)-binding Rossmann-fold domains Family:Tyrosine-dependent oxidoreductases 86 c3o8oB_ not modelled 16.9 25 PDB header:transferase Chain: B: PDB Molecule:6-phosphofructokinase subunit beta; PDBTitle: structure of phosphofructokinase from saccharomyces cerevisiae 87 c3llvA_ not modelled 16.4 5 PDB header:nad(p) binding protein Chain: A: PDB Molecule:exopolyphosphatase-related protein; PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a 88 c3fwzA_ not modelled 16.1 15 PDB header:membrane protein Chain: A: PDB Molecule:inner membrane protein ybal; PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli 89 c3kvoB_ not modelled 16.0 10 PDB header:oxidoreductase Chain: B: PDB Molecule:hydroxysteroid dehydrogenase-like protein 2; PDBTitle: crystal structure of the catalytic domain of human hydroxysteroid2 dehydrogenase like 2 (hsdl2) 90 c3lasA_ not modelled 15.9 13 PDB header:lyase Chain: A: PDB Molecule:putative carbonic anhydrase; PDBTitle: crystal structure of carbonic anhydrase from streptococcus mutans to2 1.4 angstrom resolution 91 c2zroA_ not modelled 15.7 13 PDB header:hydrolase Chain: A: PDB Molecule:protein reca; PDBTitle: msreca adp form iv 92 c3i1jB_ not modelled 15.6 23 PDB header:oxidoreductase Chain: B: PDB Molecule:oxidoreductase, short chain PDBTitle: structure of a putative short chain dehydrogenase from2 pseudomonas syringae 93 c3v2hB_ not modelled 15.5 17 PDB header:oxidoreductase Chain: B: PDB Molecule:d-beta-hydroxybutyrate dehydrogenase; PDBTitle: the crystal structure of d-beta-hydroxybutyrate dehydrogenase from2 sinorhizobium meliloti 94 c2pd6D_ not modelled 15.4 7 PDB header:oxidoreductase Chain: D: PDB Molecule:estradiol 17-beta-dehydrogenase 8; PDBTitle: structure of human hydroxysteroid dehydrogenase type 8, hsd17b8 95 c3ek2D_ not modelled 15.1 10 PDB header:oxidoreductase Chain: D: PDB Molecule:enoyl-(acyl-carrier-protein) reductase (nadh); PDBTitle: crystal structure of eonyl-(acyl carrier protein) reductase2 from burkholderia pseudomallei 1719b 96 c3rkrC_ not modelled 15.0 20 PDB header:oxidoreductase Chain: C: PDB Molecule:short chain oxidoreductase; PDBTitle: crystal structure of a metagenomic short-chain oxidoreductase (sdr) in2 complex with nadp 97 c3m1aF_ not modelled 14.8 7 PDB header:oxidoreductase Chain: F: PDB Molecule:putative dehydrogenase; PDBTitle: the crystal structure of a short-chain dehydrogenase from2 streptomyces avermitilis to 2a 98 c3nklA_ not modelled 14.5 7 PDB header:oxidoreductase/lyase Chain: A: PDB Molecule:udp-d-quinovosamine 4-dehydrogenase; PDBTitle: crystal structure of udp-d-quinovosamine 4-dehydrogenase from vibrio2 fischeri 99 d1t9ha2 not modelled 14.4 20 Fold:P-loop containing nucleoside triphosphate hydrolases Superfamily:P-loop containing nucleoside triphosphate hydrolases Family:G proteins

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0