Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP37443
DateThu Jan 5 11:55:38 GMT 2012
Unique Job ID981abe20ffaa131c

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2bibA_
Top template information
PDB header:hydrolase
Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding
PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae
Confidence and coverage
Confidence:100.0% Coverage: 31%
236 residues ( 31% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MKITTVGVCIISGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWG
Secondary structure 

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   .........70.........80.........90.........100.........110.........120
Sequence  ILSAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQGRRIFPASGLVMYGEYLP
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   .........130.........140.........150.........160.........170.........180
Sequence  QAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPLTGRFLQASVIEPNCSLRAQY
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   .........190.........200.........210.........220.........230.........240
Sequence  LASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
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   .........250.........260.........270.........280.........290.........300
Sequence  GLIRSGQIFLPGRWIHWQIPLIGGICCAAFYAWLTGMQPPALRTMVALATWGMLKLSGRQ
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?
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?
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   .........310.........320.........330.........340.........350.........360
Sequence  WSGWDVWICCLAAILLMDPVAILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVS
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   .........370.........380.........390.........400.........410.........420
Sequence  LIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTFITVPLILAAMVVHLSGPLIL
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   .........430.........440.........450.........460.........470.........480
Sequence  EQGLWFLADRSLALLFWGLKSLPEGWINIAECWQWLSFSPWFLLVVWRLNAWRTLPAMCV
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   .........490.........500.........510.........520.........530.........540
Sequence  AGGLLMCWPLWQKPRPDEWQLYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLII
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   .........550.........560.........570.........580.........590.........600
Sequence  PWLHWHNLEPEGVILSHEHLDHRGGLDSILHIWPMLWIRSPLNWEHHQPCVRGEAWQWQG
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   .........610.........620.........630.........640.........650.........660
Sequence  LRFSAHWPLQGSNDKGNNHSCVVKVDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQ
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   .........670.........680.........690.........700.........710.........720
Sequence  VPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQLQGYQWIDTPHQGQT
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   .........730.........740.........750....
Sequence  TVNFSAQGWRISSLREQILPRWYHQWFGVPVDNG
Secondary structure 















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???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2bib chain A

3D model

Region: 494 - 730
Aligned: 236
Modelled: 237
Confidence: 100.0%
Identity: 16%
PDB header:hydrolase
Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding
PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae

Phyre2

PDB 1wra chain A domain 1

3D model

Region: 498 - 740
Aligned: 239
Modelled: 243
Confidence: 100.0%
Identity: 15%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Pce catalytic domain-like

Phyre2

PDB 1k07 chain A

3D model

Region: 490 - 706
Aligned: 199
Modelled: 212
Confidence: 99.6%
Identity: 16%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Zn metallo-beta-lactamase

Phyre2

PDB 1qh5 chain A

3D model

Region: 499 - 681
Aligned: 169
Modelled: 182
Confidence: 99.6%
Identity: 16%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Glyoxalase II (hydroxyacylglutathione hydrolase)

Phyre2

PDB 2dkf chain A domain 1

3D model

Region: 500 - 708
Aligned: 194
Modelled: 203
Confidence: 99.5%
Identity: 19%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: beta-CASP RNA-metabolising hydrolases

Phyre2

PDB 2xf4 chain A

3D model

Region: 499 - 680
Aligned: 166
Modelled: 182
Confidence: 99.5%
Identity: 19%
PDB header:hydrolase
Chain: A: PDB Molecule:hydroxyacylglutathione hydrolase;
PDBTitle: crystal structure of salmonella enterica serovar2 typhimurium ycbl

Phyre2

PDB 1xm8 chain A

3D model

Region: 499 - 681
Aligned: 166
Modelled: 175
Confidence: 99.5%
Identity: 16%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Glyoxalase II (hydroxyacylglutathione hydrolase)

Phyre2

PDB 2i7t chain A domain 1

3D model

Region: 497 - 706
Aligned: 171
Modelled: 180
Confidence: 99.5%
Identity: 17%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: beta-CASP RNA-metabolising hydrolases

Phyre2

PDB 3kl7 chain A

3D model

Region: 490 - 711
Aligned: 196
Modelled: 209
Confidence: 99.5%
Identity: 10%
PDB header:hydrolase
Chain: A: PDB Molecule:putative metal-dependent hydrolase;
PDBTitle: crystal structure of putative metal-dependent hydrolase2 (yp_001302908.1) from parabacteroides distasonis atcc 8503 at 2.30 a3 resolution

Phyre2

PDB 2ohi chain B

3D model

Region: 507 - 711
Aligned: 193
Modelled: 205
Confidence: 99.5%
Identity: 17%
PDB header:oxidoreductase
Chain: B: PDB Molecule:type a flavoprotein fpra;
PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state

Phyre2

PDB 2p4z chain A

3D model

Region: 496 - 720
Aligned: 209
Modelled: 210
Confidence: 99.5%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:metal-dependent hydrolases of the beta-lactamase
PDBTitle: a ferredoxin-like metallo-beta-lactamase superfamily protein from2 thermoanaerobacter tengcongensis

Phyre2

PDB 2qed chain A domain 1

3D model

Region: 499 - 681
Aligned: 164
Modelled: 182
Confidence: 99.4%
Identity: 19%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Glyoxalase II (hydroxyacylglutathione hydrolase)

Phyre2

PDB 3zq4 chain C

3D model

Region: 509 - 716
Aligned: 199
Modelled: 202
Confidence: 99.4%
Identity: 17%
PDB header:hydrolase
Chain: C: PDB Molecule:ribonuclease j 1;
PDBTitle: unusual, dual endo- and exo-nuclease activity in the degradosome2 explained by crystal structure analysis of rnase j1

Phyre2

PDB 2zwr chain A

3D model

Region: 500 - 680
Aligned: 169
Modelled: 181
Confidence: 99.4%
Identity: 18%
PDB header:hydrolase
Chain: A: PDB Molecule:metallo-beta-lactamase superfamily protein;
PDBTitle: crystal structure of ttha1623 from thermus thermophilus hb8

Phyre2

PDB 2q0i chain A domain 1

3D model

Region: 500 - 666
Aligned: 154
Modelled: 167
Confidence: 99.3%
Identity: 24%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: PqsE-like

Phyre2

PDB 2gcu chain D

3D model

Region: 502 - 680
Aligned: 168
Modelled: 174
Confidence: 99.3%
Identity: 13%
PDB header:hydrolase
Chain: D: PDB Molecule:putative hydroxyacylglutathione hydrolase 3;
PDBTitle: x-ray structure of gene product from arabidopsis thaliana2 at1g53580

Phyre2

PDB 1zkp chain D

3D model

Region: 492 - 720
Aligned: 208
Modelled: 220
Confidence: 99.3%
Identity: 18%
PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical protein ba1088;
PDBTitle: 1.5a resolution crystal structure of a metallo beta lactamase family2 protein, the elac homolgue of bacillus anthracis, a putative3 ribonuclease

Phyre2

PDB 1m2x chain A

3D model

Region: 510 - 681
Aligned: 160
Modelled: 172
Confidence: 99.3%
Identity: 18%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Zn metallo-beta-lactamase

Phyre2

PDB 2gmn chain A domain 1

3D model

Region: 501 - 669
Aligned: 157
Modelled: 169
Confidence: 99.3%
Identity: 17%
Fold: Metallo-hydrolase/oxidoreductase
Superfamily: Metallo-hydrolase/oxidoreductase
Family: Zn metallo-beta-lactamase

Phyre2

PDB 3r2u chain C

3D model

Region: 511 - 680
Aligned: 158
Modelled: 165
Confidence: 99.3%
Identity: 18%
PDB header:hydrolase
Chain: C: PDB Molecule:metallo-beta-lactamase family protein;
PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col

Phyre2
1

c2bibA_
2

d1wraa1
3

d1k07a_
4

d1qh5a_
5

d2dkfa1
6

c2xf4A_
7

d1xm8a_
8

d2i7ta1
9

c3kl7A_
10

c2ohiB_
11

c2p4zA_
12

d2qeda1
13

c3zq4C_
14

c2zwrA_
15

d2q0ia1
16

c2gcuD_
17

c1zkpD_
18

d1m2xa_
19

d2gmna1
20

c3r2uC_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2bibA_



100.0 16 PDB header:hydrolase
Chain: A: PDB Molecule:teichoic acid phosphorylcholine esterase/ choline binding
PDBTitle: crystal structure of the complete modular teichioic acid2 phosphorylcholine esterase pce (cbpe) from streptococcus3 pneumoniae
2d1wraa1



100.0 15 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Pce catalytic domain-like
3d1k07a_



99.6 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
4d1qh5a_



99.6 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Glyoxalase II (hydroxyacylglutathione hydrolase)
5d2dkfa1



99.5 19 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:beta-CASP RNA-metabolising hydrolases
6c2xf4A_



99.5 19 PDB header:hydrolase
Chain: A: PDB Molecule:hydroxyacylglutathione hydrolase;
PDBTitle: crystal structure of salmonella enterica serovar2 typhimurium ycbl
7d1xm8a_



99.5 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Glyoxalase II (hydroxyacylglutathione hydrolase)
8d2i7ta1



99.5 17 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:beta-CASP RNA-metabolising hydrolases
9c3kl7A_



99.5 10 PDB header:hydrolase
Chain: A: PDB Molecule:putative metal-dependent hydrolase;
PDBTitle: crystal structure of putative metal-dependent hydrolase2 (yp_001302908.1) from parabacteroides distasonis atcc 8503 at 2.30 a3 resolution
10c2ohiB_



99.5 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:type a flavoprotein fpra;
PDBTitle: crystal structure of coenzyme f420h2 oxidase (fpra), a diiron2 flavoprotein, reduced state
11c2p4zA_



99.5 18 PDB header:hydrolase
Chain: A: PDB Molecule:metal-dependent hydrolases of the beta-lactamase
PDBTitle: a ferredoxin-like metallo-beta-lactamase superfamily protein from2 thermoanaerobacter tengcongensis
12d2qeda1



99.4 19 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Glyoxalase II (hydroxyacylglutathione hydrolase)
13c3zq4C_



99.4 17 PDB header:hydrolase
Chain: C: PDB Molecule:ribonuclease j 1;
PDBTitle: unusual, dual endo- and exo-nuclease activity in the degradosome2 explained by crystal structure analysis of rnase j1
14c2zwrA_



99.4 18 PDB header:hydrolase
Chain: A: PDB Molecule:metallo-beta-lactamase superfamily protein;
PDBTitle: crystal structure of ttha1623 from thermus thermophilus hb8
15d2q0ia1



99.3 24 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:PqsE-like
16c2gcuD_



99.3 13 PDB header:hydrolase
Chain: D: PDB Molecule:putative hydroxyacylglutathione hydrolase 3;
PDBTitle: x-ray structure of gene product from arabidopsis thaliana2 at1g53580
17c1zkpD_



99.3 18 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:hypothetical protein ba1088;
PDBTitle: 1.5a resolution crystal structure of a metallo beta lactamase family2 protein, the elac homolgue of bacillus anthracis, a putative3 ribonuclease
18d1m2xa_



99.3 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
19d2gmna1



99.3 17 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
20c3r2uC_



99.3 18 PDB header:hydrolase
Chain: C: PDB Molecule:metallo-beta-lactamase family protein;
PDBTitle: 2.1 angstrom resolution crystal structure of metallo-beta-lactamase2 from staphylococcus aureus subsp. aureus col
21c3bk2A_



not modelled 99.3 19 PDB header:hydrolase
Chain: A: PDB Molecule:metal dependent hydrolase;
PDBTitle: crystal structure analysis of the rnase j/ump complex
22c3tp9B_



not modelled 99.2 22 PDB header:hydrolase
Chain: B: PDB Molecule:beta-lactamase and rhodanese domain protein;
PDBTitle: crystal structure of alicyclobacillus acidocaldarius protein with2 beta-lactamase and rhodanese domains
23c3g1pA_



not modelled 99.2 16 PDB header:lyase
Chain: A: PDB Molecule:protein phnp;
PDBTitle: crystals structure of phnp from e.coli k-12
24c2az4A_



not modelled 99.2 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein ef2904;
PDBTitle: crystal structure of a protein of unknown function from enterococcus2 faecalis v583
25c2p18A_



not modelled 99.2 14 PDB header:hydrolase
Chain: A: PDB Molecule:glyoxalase ii;
PDBTitle: crystal structure of the leishmania infantum glyoxalase ii
26c3lvzA_



not modelled 99.2 17 PDB header:hydrolase
Chain: A: PDB Molecule:blr6230 protein;
PDBTitle: new refinement of the crystal structure of bjp-1, a subclass b32 metallo-beta-lactamase of bradyrhizobium japonicum
27c1vmeB_



not modelled 99.2 24 PDB header:electron transport
Chain: B: PDB Molecule:flavoprotein;
PDBTitle: crystal structure of flavoprotein (tm0755) from thermotoga maritima at2 1.80 a resolution
28c2ycbA_



not modelled 99.2 18 PDB header:hydrolase
Chain: A: PDB Molecule:cleavage and polyadenylation specificity factor;
PDBTitle: structure of the archaeal beta-casp protein with n-terminal2 kh domains from methanothermobacter thermautotrophicus
29c3adrA_



not modelled 99.2 22 PDB header:signaling protein
Chain: A: PDB Molecule:putative uncharacterized protein st1585;
PDBTitle: the first crystal structure of an archaeal metallo-beta-lactamase2 superfamily protein; st1585 from sulfolobus tokodaii
30d2aioa1



not modelled 99.2 19 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
31c2i7xA_



not modelled 99.2 16 PDB header:rna binding protein, protein binding
Chain: A: PDB Molecule:protein cft2;
PDBTitle: structure of yeast cpsf-100 (ydh1p)
32d2i7xa1



not modelled 99.2 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:beta-CASP RNA-metabolising hydrolases
33c3zwfA_



not modelled 99.2 20 PDB header:hydrolase
Chain: A: PDB Molecule:zinc phosphodiesterase elac protein 1;
PDBTitle: crystal structure of human trnase z, short form (elac1).
34c1e5dA_



not modelled 99.1 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:rubredoxin\:oxygen oxidoreductase;
PDBTitle: rubredoxin oxygen:oxidoreductase (roo) from anaerobe2 desulfovibrio gigas
35c3af5A_



not modelled 99.1 17 PDB header:hydrolase
Chain: A: PDB Molecule:putative uncharacterized protein ph1404;
PDBTitle: the crystal structure of an archaeal cpsf subunit, ph1404 from2 pyrococcus horikoshii
36d1mqoa_



not modelled 99.1 17 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
37c2q9uB_



not modelled 99.1 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:a-type flavoprotein;
PDBTitle: crystal structure of the flavodiiron protein from giardia2 intestinalis
38c2xr1A_



not modelled 99.1 16 PDB header:hydrolase
Chain: A: PDB Molecule:cleavage and polyadenylation specificity factor 100 kd
PDBTitle: dimeric archaeal cleavage and polyadenylation specificity2 factor with n-terminal kh domains (kh-cpsf) from methanosarcina3 mazei
39c2xr1B_



not modelled 99.1 16 PDB header:hydrolase
Chain: B: PDB Molecule:cleavage and polyadenylation specificity factor 100 kd
PDBTitle: dimeric archaeal cleavage and polyadenylation specificity2 factor with n-terminal kh domains (kh-cpsf) from methanosarcina3 mazei
40d1ycga2



not modelled 99.1 19 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:ROO N-terminal domain-like
41d1zkpa1



not modelled 99.1 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:YhfI-like
42d1vmea2



not modelled 99.1 21 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:ROO N-terminal domain-like
43d1znba_



not modelled 99.1 21 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
44c2cfuA_



not modelled 99.1 24 PDB header:hydrolase
Chain: A: PDB Molecule:sdsa1;
PDBTitle: crystal structure of sdsa1, an alkylsulfatase from2 pseudomonas aeruginosa, in complex with 1-decane-sulfonic-3 acid.
45d1y44a1



not modelled 99.1 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:RNase Z-like
46d1ztca1



not modelled 99.1 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:TM0894-like
47d2cfua2



not modelled 99.0 24 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Alkylsulfatase-like
48c3eshB_



not modelled 99.0 18 PDB header:hydrolase
Chain: B: PDB Molecule:protein similar to metal-dependent hydrolase;
PDBTitle: crystal structure of a probable metal-dependent hydrolase2 from staphylococcus aureus. northeast structural genomics3 target zr314
49c3l6nA_



not modelled 99.0 17 PDB header:hydrolase
Chain: A: PDB Molecule:metallo-beta-lactamase;
PDBTitle: crystal structure of metallo-beta-lactamase ind-7
50c1ychD_



not modelled 99.0 16 PDB header:oxidoreductase
Chain: D: PDB Molecule:nitric oxide reductase;
PDBTitle: x-ray crystal structures of moorella thermoacetica fpra.2 novel diiron site structure and mechanistic insights into3 a scavenging nitric oxide reductase
51c2zo4A_



not modelled 99.0 20 PDB header:hydrolase
Chain: A: PDB Molecule:metallo-beta-lactamase family protein;
PDBTitle: crystal structure of metallo-beta-lactamase family protein ttha14292 from thermus thermophilus hb8
52d1ko3a_



not modelled 99.0 19 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
53c3hnnD_



not modelled 98.9 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:putative diflavin flavoprotein a 5;
PDBTitle: crystal structure of putative diflavin flavoprotein a 5 (fragment 1-2 254) from nostoc sp. pcc 7120, northeast structural genomics3 consortium target nsr435a
54d1p9ea_



not modelled 98.9 24 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Methyl parathion hydrolase
55c1p9eA_



not modelled 98.9 24 PDB header:hydrolase
Chain: A: PDB Molecule:methyl parathion hydrolase;
PDBTitle: crystal structure analysis of methyl parathion hydrolase from2 pseudomonas sp wbc-3
56d2cbna1



not modelled 98.9 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:RNase Z-like
57d1e5da2



not modelled 98.9 21 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:ROO N-terminal domain-like
58c2wylF_



not modelled 98.9 16 PDB header:hydrolase
Chain: F: PDB Molecule:l-ascorbate-6-phosphate lactonase ulag;
PDBTitle: apo structure of a metallo-b-lactamase
59c2fhxB_



not modelled 98.8 22 PDB header:hydrolase, metal binding protein
Chain: B: PDB Molecule:spm-1;
PDBTitle: pseudomonas aeruginosa spm-1 metallo-beta-lactamase
60c3md7A_



not modelled 98.8 16 PDB header:hydrolase
Chain: A: PDB Molecule:beta-lactamase-like;
PDBTitle: crystal structure of a beta-lactamase-like protein bound to gmp from2 brucella melitensis
61d1vjna_



not modelled 98.8 23 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Hypothetical protein TM0207
62c2r2dC_



not modelled 98.8 19 PDB header:hydrolase
Chain: C: PDB Molecule:zn-dependent hydrolases;
PDBTitle: structure of a quorum-quenching lactonase (aiib) from agrobacterium2 tumefaciens
63d1jjta_



not modelled 98.8 21 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
64c3sd9B_



not modelled 98.8 11 PDB header:hydrolase
Chain: B: PDB Molecule:beta-lactamase;
PDBTitle: crystal structure of serratia fonticola sfh-i: source of the2 nucleophile in the catalytic mechanism of mono-zinc metallo-beta-3 lactamases
65d1xtoa_



not modelled 98.7 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Coenzyme PQQ synthesis protein B, PqqB
66c3spuB_



not modelled 98.7 20 PDB header:hydrolase
Chain: B: PDB Molecule:beta-lactamase ndm-1;
PDBTitle: apo ndm-1 crystal structure
67d1x8ha_



not modelled 98.7 16 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Zn metallo-beta-lactamase
68c3h3eA_



not modelled 98.7 15 PDB header:structural genomics, metal binding prote
Chain: A: PDB Molecule:uncharacterized protein tm1679;
PDBTitle: crystal structure of tm1679, a metal-dependent hydrolase of2 the beta-lactamase superfamily
69c2yz3B_



not modelled 98.7 19 PDB header:hydrolase
Chain: B: PDB Molecule:metallo-beta-lactamase;
PDBTitle: crystallographic investigation of inhibition mode of the2 vim-2 metallo-beta-lactamase from pseudomonas aeruginosa3 with mercaptocarboxylate inhibitor
70c3aj3A_



not modelled 98.7 26 PDB header:hydrolase
Chain: A: PDB Molecule:4-pyridoxolactonase;
PDBTitle: crystal structure of selenomethionine substituted 4-pyridoxolactonase2 from mesorhizobium loti
71c2br6A_



not modelled 98.6 19 PDB header:hydrolase
Chain: A: PDB Molecule:aiia-like protein;
PDBTitle: crystal structure of quorum-quenching n-acyl homoserine2 lactone lactonase
72c3rpcD_



not modelled 98.5 14 PDB header:hydrolase
Chain: D: PDB Molecule:possible metal-dependent hydrolase;
PDBTitle: the crystal structure of a possible metal-dependent hydrolase from2 veillonella parvula dsm 2008
73c3rkjA_



not modelled 98.5 19 PDB header:hydrolase
Chain: A: PDB Molecule:beta-lactamase ndm-1;
PDBTitle: crystal structure of new delhi metallo-beta-lactamase-1 from2 klebsiella pnueumoniae
74d2az4a1



not modelled 98.4 18 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:beta-CASP RNA-metabolising hydrolases
75d2e7ya1



not modelled 98.4 22 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:RNase Z-like
76c3bv6D_



not modelled 98.3 14 PDB header:hydrolase
Chain: D: PDB Molecule:metal-dependent hydrolase;
PDBTitle: crystal structure of uncharacterized metallo protein from vibrio2 cholerae with beta-lactamase like fold
77d2p97a1



not modelled 97.9 14 Fold:Metallo-hydrolase/oxidoreductase
Superfamily:Metallo-hydrolase/oxidoreductase
Family:Ava3068-like
78d2nu7b1



not modelled 89.9 12 Fold:Flavodoxin-like
Superfamily:Succinyl-CoA synthetase domains
Family:Succinyl-CoA synthetase domains
79d1eucb1



not modelled 89.7 8 Fold:Flavodoxin-like
Superfamily:Succinyl-CoA synthetase domains
Family:Succinyl-CoA synthetase domains
80c2gm2A_



not modelled 89.4 20 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: nmr structure of xanthomonas campestris xcc1710: northeast2 structural genomics consortium target xcr35
81d2fi9a1



not modelled 87.1 8 Fold:MTH938-like
Superfamily:MTH938-like
Family:MTH938-like
82d2z06a1



not modelled 84.8 18 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:TTHA0625-like
83d2csua3



not modelled 82.0 16 Fold:Flavodoxin-like
Superfamily:Succinyl-CoA synthetase domains
Family:Succinyl-CoA synthetase domains
84c2k2eA_



not modelled 80.7 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein bp2786;
PDBTitle: solution nmr structure of bordetella pertussis protein2 bp2786, a mth938-like domain. northeast structural3 genomics consortium target ber31
85d1t70a_



not modelled 79.5 14 Fold:Metallo-dependent phosphatases
Superfamily:Metallo-dependent phosphatases
Family:DR1281-like
86d2fvta1



not modelled 79.4 8 Fold:MTH938-like
Superfamily:MTH938-like
Family:MTH938-like
87c1u2pA_



not modelled 78.8 19 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-
PDBTitle: crystal structure of mycobacterium tuberculosis low2 molecular protein tyrosine phosphatase (mptpa) at 1.9a3 resolution
88d2q4qa1



not modelled 78.0 8 Fold:MTH938-like
Superfamily:MTH938-like
Family:MTH938-like
89c2fekA_



not modelled 77.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:low molecular weight protein-tyrosine-
PDBTitle: structure of a protein tyrosine phosphatase
90d2ioja1



not modelled 75.1 20 Fold:MurF and HprK N-domain-like
Superfamily:HprK N-terminal domain-like
Family:DRTGG domain
91c2wmyH_



not modelled 74.1 13 PDB header:hydrolase
Chain: H: PDB Molecule:putative acid phosphatase wzb;
PDBTitle: crystal structure of the tyrosine phosphatase wzb from2 escherichia coli k30 in complex with sulphate.
92d1vfsa2



not modelled 72.9 18 Fold:TIM beta/alpha-barrel
Superfamily:PLP-binding barrel
Family:Alanine racemase-like, N-terminal domain
93d1bd0a2



not modelled 70.5 11 Fold:TIM beta/alpha-barrel
Superfamily:PLP-binding barrel
Family:Alanine racemase-like, N-terminal domain
94c1vftA_



not modelled 69.5 18 PDB header:isomerase
Chain: A: PDB Molecule:alanine racemase;
PDBTitle: crystal structure of l-cycloserine-bound form of alanine2 racemase from d-cycloserine-producing streptomyces3 lavendulae
95d1y1la_



not modelled 69.1 18 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
96c2csuB_



not modelled 68.7 10 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:457aa long hypothetical protein;
PDBTitle: crystal structure of ph0766 from pyrococcus horikoshii ot3
97c3rh0A_



not modelled 68.5 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:arsenate reductase;
PDBTitle: corynebacterium glutamicum mycothiol/mycoredoxin1-dependent arsenate2 reductase cg_arsc2
98c2nu9E_



not modelled 67.0 13 PDB header:ligase
Chain: E: PDB Molecule:succinyl-coa synthetase beta chain;
PDBTitle: c123at mutant of e. coli succinyl-coa synthetase2 orthorhombic crystal form
99c3oo2A_



not modelled 66.2 18 PDB header:isomerase
Chain: A: PDB Molecule:alanine racemase 1;
PDBTitle: 2.37 angstrom resolution crystal structure of an alanine racemase2 (alr) from staphylococcus aureus subsp. aureus col
100d1gdha2



not modelled 65.7 16 Fold:Flavodoxin-like
Superfamily:Formate/glycerate dehydrogenase catalytic domain-like
Family:Formate/glycerate dehydrogenases, substrate-binding domain
101c2r79A_



not modelled 65.5 10 PDB header:transport protein
Chain: A: PDB Molecule:periplasmic binding protein;
PDBTitle: crystal structure of a periplasmic heme binding protein from2 pseudomonas aeruginosa
102c2dy3B_



not modelled 65.3 18 PDB header:isomerase
Chain: B: PDB Molecule:alanine racemase;
PDBTitle: crystal structure of alanine racemase from corynebacterium glutamicum
103d2c4ka2



not modelled 64.9 14 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like
104d1n2za_



not modelled 64.7 8 Fold:Chelatase-like
Superfamily:"Helical backbone" metal receptor
Family:TroA-like
105c1xfcB_



not modelled 64.4 9 PDB header:isomerase
Chain: B: PDB Molecule:alanine racemase;
PDBTitle: the 1.9 a crystal structure of alanine racemase from mycobacterium2 tuberculosis contains a conserved entryway into the active site
106c2vqqA_



not modelled 64.2 19 PDB header:hydrolase
Chain: A: PDB Molecule:histone deacetylase 4;
PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor
107c3jx9B_



not modelled 64.1 14 PDB header:isomerase
Chain: B: PDB Molecule:putative phosphoheptose isomerase;
PDBTitle: crystal structure of putative phosphoheptose isomerase2 (yp_001815198.1) from exiguobacterium sp. 255-15 at 1.95 a resolution
108c3ew8A_



not modelled 61.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:histone deacetylase 8;
PDBTitle: crystal structure analysis of human hdac8 d101l variant
109c1vl6C_



not modelled 61.2 9 PDB header:oxidoreductase
Chain: C: PDB Molecule:malate oxidoreductase;
PDBTitle: crystal structure of nad-dependent malic enzyme (tm0542) from2 thermotoga maritima at 2.61 a resolution
110c3efhB_



not modelled 59.6 15 PDB header:transferase
Chain: B: PDB Molecule:ribose-phosphate pyrophosphokinase 1;
PDBTitle: crystal structure of human phosphoribosyl pyrophosphate2 synthetase 1
111c3e6eC_



not modelled 57.7 15 PDB header:isomerase
Chain: C: PDB Molecule:alanine racemase;
PDBTitle: crystal structure of alanine racemase from e.faecalis2 complex with cycloserine
112c3oo2B_



not modelled 57.5 18 PDB header:isomerase
Chain: B: PDB Molecule:alanine racemase 1;
PDBTitle: 2.37 angstrom resolution crystal structure of an alanine racemase2 (alr) from staphylococcus aureus subsp. aureus col
113c2r7aC_



not modelled 56.5 17 PDB header:transport protein
Chain: C: PDB Molecule:bacterial heme binding protein;
PDBTitle: crystal structure of a periplasmic heme binding protein2 from shigella dysenteriae
114d1jf8a_



not modelled 56.5 9 Fold:Phosphotyrosine protein phosphatases I-like
Superfamily:Phosphotyrosine protein phosphatases I
Family:Low-molecular-weight phosphotyrosine protein phosphatases
115c3co8B_



not modelled 55.5 18 PDB header:isomerase
Chain: B: PDB Molecule:alanine racemase;
PDBTitle: crystal structure of alanine racemase from oenococcus oeni
116c1ww8A_



not modelled 55.4 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:malate oxidoreductase;
PDBTitle: crystal structure of malic enzyme from pyrococcus2 horikoshii ot3
117c2a9fB_



not modelled 53.9 7 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative malic enzyme ((s)-malate:nad+
PDBTitle: crystal structure of a putative malic enzyme ((s)-2 malate:nad+ oxidoreductase (decarboxylating))
118d1ko7a1



not modelled 53.4 6 Fold:MurF and HprK N-domain-like
Superfamily:HprK N-terminal domain-like
Family:HPr kinase/phoshatase HprK N-terminal domain
119c1t6zB_



not modelled 53.1 9 PDB header:transferase
Chain: B: PDB Molecule:riboflavin kinase/fmn adenylyltransferase;
PDBTitle: crystal structure of riboflavin bound tm379
120d1u9ya2



not modelled 52.3 13 Fold:PRTase-like
Superfamily:PRTase-like
Family:Phosphoribosylpyrophosphate synthetase-like

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0