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 Protein Homology/analogY Recognition Engine V 2.0


 

Fold library entry viewer: c2vqqA_

Fold library idPDB HeaderMoleculeTitle
c2vqqA_PDB header: hydrolaseChain: A: PDB Molecule: histone deacetylase 4;PDBTitle: structure of hdac4 catalytic domain (a double cysteine-to-2 alanine mutant) bound to a trifluoromethylketone inhbitor


Added to library: Tue Mar 16 13:28:55 2010
 
Links to external resources


 1........10.........20.........30.........40.........50.........60.........70
Sequence RFTTGLVYDTLMLKHQHAGRIQSIWSRLQETGLRGKCEAIRGRKATLEELQTVHSEAHTLLYGTNPLVDS
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Known secondary structure (DSSP)

S

GGG
S




TSS





TTTS
S




T
 .........80.........90.........100.........110.........120.........130.........140
Sequence DTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQR
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Known secondary structure (DSSP) TSTTTSSS

SS

TT
BTTB
BTTBSS
 .........150.........160.........170.........180.........190.........200.........210
Sequence LSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGL
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Known secondary structure (DSSP)

S

SSS

TTT
TT
TTT
STT



TT


SGGGTT

S
S
 .........220.........230.........240.........250.........260.........270.........280
Sequence DPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRI
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Known secondary structure (DSSP) SS


T

S

TTBTTS
TTS



B
TTSGGG
 .........290.........300.........310.........320.........330.........340.........350
Sequence VLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTA
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Known secondary structure (DSSP)




TT






T



TTT
GGGTS



T
 .........360.
Sequence GRSLIEAQTCE
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Known secondary structure (DSSP) TS
T


Download:PDB structure FASTA sequence

Hidden Markov model

Image coloured by rainbow N → C terminus
Interactive 3D view in JSmol


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Please cite: The Phyre2 web portal for protein modeling, prediction and analysis
Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]
 
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Michael Sternberg 
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