Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	I	K	T	R	F	A	P	S	P	T	G	Y	L	H	V	G	G	A	R	T	A	L	Y	S	W	L	F	A	R	N	H	G	G	E	F	V	L	R	I	E	D	T	D	L	E	R	S	T	P	E	A	I	E	A	I	M	D	G
Secondary structure
SS confidence
Disorder		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		M	N	W	L	S	L	E	W	D	E	G	P	Y	Y	Q	T	K	R	F	D	R	Y	N	A	V	I	D	Q	M	L	E	E	G	T	A	Y	K	C	Y	C	S	K	E	R	L	E	A	L	R	E	E	Q	M	A	K	G	E	K	P	R
Secondary structure
SS confidence
Disorder																																																				?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	D	G	R	C	R	H	S	H	E	H	H	A	D	D	E	P	C	V	V	R	F	A	N	P	Q	E	G	S	V	V	F	D	D	Q	I	R	G	P	I	E	F	S	N	Q	E	L	D	D	L	I	I	R	R	T	D	G	S	P	T
Secondary structure
SS confidence
Disorder			?					?	?			?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	N	F	C	V	V	V	D	D	W	D	M	E	I	T	H	V	I	R	G	E	D	H	I	N	N	T	P	R	Q	I	N	I	L	K	A	L	K	A	P	V	P	V	Y	A	H	V	S	M	I	N	G	D	D	G	K	K	L	S	K
Secondary structure
SS confidence
Disorder																																																						?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		R	H	G	A	V	S	V	M	Q	Y	R	D	D	G	Y	L	P	E	A	L	L	N	Y	L	V	R	L	G	W	S	H	G	D	Q	E	I	F	T	R	E	E	M	I	K	Y	F	T	L	N	A	V	S	K	S	A	S	A	F	N	T
Secondary structure
SS confidence
Disorder																																																						?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	K	L	L	W	L	N	H	H	Y	I	N	A	L	P	P	E	Y	V	A	T	H	L	Q	W	H	I	E	Q	E	N	I	D	T	R	N	G	P	Q	L	A	D	L	V	K	L	L	G	E	R	C	K	T	L	K	E	M	A	Q	S
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		C	R	Y	F	Y	E	D	F	A	E	F	D	A	D	A	A	K	K	H	L	R	P	V	A	R	Q	P	L	E	V	V	R	D	K	L	A	A	I	T	D	W	T	A	E	N	V	H	H	A	I	Q	A	T	A	D	E	L	E	V	G
Secondary structure
SS confidence
Disorder												?																																														?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
Sequence		M	G	K	V	G	M	P	L	R	V	A	V	T	G	A	G	Q	S	P	A	L	D	V	T	V	H	A	I	G	K	T	R	S	I	E	R	I	N	K	A	L	D	F	I	A	E	R	E	N	Q	Q
Secondary structure
SS confidence
Disorder																		?	?	?	?																										?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2cfo chain A Region: 2 - 469 Aligned: 468 Modelled: 467 Confidence: 100.0% Identity: 41% PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu Phyre2 PDB 3al0 chain C Region: 3 - 466 Aligned: 451 Modelled: 464 Confidence: 100.0% Identity: 36% PDB header:ligase/rna Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c, glutamyl- PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state. Phyre2 PDB 2ja2 chain A Region: 2 - 460 Aligned: 457 Modelled: 459 Confidence: 100.0% Identity: 37% PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: mycobacterium tuberculosis glutamyl-trna synthetase Phyre2 PDB 3afh chain A Region: 3 - 466 Aligned: 451 Modelled: 453 Confidence: 100.0% Identity: 36% PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 2; PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog Phyre2 PDB 1g59 chain A Region: 3 - 462 Aligned: 452 Modelled: 460 Confidence: 100.0% Identity: 37% PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: glutamyl-trna synthetase complexed with trna(glu). Phyre2 PDB 2o5r chain A Region: 3 - 461 Aligned: 450 Modelled: 459 Confidence: 100.0% Identity: 40% PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 1; PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution Phyre2 PDB 1j09 chain A domain 2 Region: 3 - 298 Aligned: 290 Modelled: 296 Confidence: 100.0% Identity: 41% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1gtr chain A domain 2 Region: 2 - 290 Aligned: 286 Modelled: 289 Confidence: 100.0% Identity: 23% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1nzj chain A Region: 2 - 297 Aligned: 266 Modelled: 270 Confidence: 100.0% Identity: 36% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 2hz7 chain A Region: 2 - 317 Aligned: 291 Modelled: 291 Confidence: 100.0% Identity: 26% PDB header:ligase Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of the glutaminyl-trna synthetase from2 deinococcus radiodurans Phyre2 PDB 1exd chain A Region: 2 - 317 Aligned: 280 Modelled: 280 Confidence: 100.0% Identity: 23% PDB header:ligase/rna Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of a tight-binding glutamine trna bound2 to glutamine aminoacyl trna synthetase Phyre2 PDB 1irx chain A Region: 2 - 460 Aligned: 447 Modelled: 451 Confidence: 100.0% Identity: 14% PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of class i lysyl-trna synthetase Phyre2 PDB 3aii chain A Region: 2 - 316 Aligned: 283 Modelled: 293 Confidence: 100.0% Identity: 29% PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: archaeal non-discriminating glutamyl-trna synthetase from2 methanothermobacter thermautotrophicus Phyre2 PDB 1f7u chain A domain 2 Region: 2 - 308 Aligned: 294 Modelled: 307 Confidence: 100.0% Identity: 15% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1u0b chain B Region: 7 - 423 Aligned: 370 Modelled: 397 Confidence: 100.0% Identity: 15% PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys Phyre2 PDB 1li5 chain A domain 2 Region: 2 - 285 Aligned: 244 Modelled: 246 Confidence: 100.0% Identity: 16% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 2d5b chain A domain 2 Region: 3 - 289 Aligned: 283 Modelled: 284 Confidence: 100.0% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 3sp1 chain B Region: 7 - 423 Aligned: 370 Modelled: 402 Confidence: 100.0% Identity: 14% PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi Phyre2 PDB 1irx chain A domain 2 Region: 2 - 279 Aligned: 251 Modelled: 253 Confidence: 100.0% Identity: 17% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 PDB 1pfv chain A domain 2 Region: 3 - 293 Aligned: 280 Modelled: 280 Confidence: 100.0% Identity: 14% Fold: Adenine nucleotide alpha hydrolase-like Superfamily: Nucleotidylyl transferase Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain Phyre2 1 c2cfoA_ 2 c3al0C_ 3 c2ja2A_ 4 c3afhA_ 5 c1g59A_ 6 c2o5rA_ 7 d1j09a2 8 d1gtra2 9 d1nzja_ 10 c2hz7A_ 11 c1exdA_ 12 c1irxA_ 13 c3aiiA_ 14 d1f7ua2 15 c1u0bB_ 16 d1li5a2 17 d2d5ba2 18 c3sp1B_ 19 d1irxa2 20 d1pfva2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2cfoA_ 100.0 41 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu 2 c3al0C_ 100.0 36 PDB header:ligase/rna Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c, glutamyl- PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state. 3 c2ja2A_ 100.0 37 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: mycobacterium tuberculosis glutamyl-trna synthetase 4 c3afhA_ 100.0 36 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 2; PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog 5 c1g59A_ 100.0 37 PDB header:ligase/rna Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: glutamyl-trna synthetase complexed with trna(glu). 6 c2o5rA_ 100.0 40 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase 1; PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution 7 d1j09a2 100.0 41 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 8 d1gtra2 100.0 23 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 9 d1nzja_ 100.0 36 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 10 c2hz7A_ 100.0 26 PDB header:ligase Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of the glutaminyl-trna synthetase from2 deinococcus radiodurans 11 c1exdA_ 100.0 23 PDB header:ligase/rna Chain: A: PDB Molecule:glutaminyl-trna synthetase; PDBTitle: crystal structure of a tight-binding glutamine trna bound2 to glutamine aminoacyl trna synthetase 12 c1irxA_ 100.0 14 PDB header:ligase Chain: A: PDB Molecule:lysyl-trna synthetase; PDBTitle: crystal structure of class i lysyl-trna synthetase 13 c3aiiA_ 100.0 29 PDB header:ligase Chain: A: PDB Molecule:glutamyl-trna synthetase; PDBTitle: archaeal non-discriminating glutamyl-trna synthetase from2 methanothermobacter thermautotrophicus 14 d1f7ua2 100.0 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 15 c1u0bB_ 100.0 15 PDB header:ligase/rna Chain: B: PDB Molecule:cysteinyl trna; PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys 16 d1li5a2 100.0 16 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 17 d2d5ba2 100.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 18 c3sp1B_ 100.0 14 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi 19 d1irxa2 100.0 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 20 d1pfva2 100.0 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 21 d1j09a1 not modelled 100.0 29 Fold:An anticodon-binding domain of class I aminoacyl-tRNA synthetases Superfamily:An anticodon-binding domain of class I aminoacyl-tRNA synthetases Family:C-terminal domain of glutamyl-tRNA synthetase (GluRS) 22 c3tqoA_ not modelled 100.0 15 PDB header:ligase Chain: A: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: structure of the cysteinyl-trna synthetase (cyss) from coxiella2 burnetii. 23 c3c8zB_ not modelled 99.9 19 PDB header:ligase Chain: B: PDB Molecule:cysteinyl-trna synthetase; PDBTitle: the 1.6 a crystal structure of mshc: the rate limiting2 enzyme in the mycothiol biosynthetic pathway 24 c3fnrA_ not modelled 99.9 16 PDB header:transferase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni; 25 c2x1lC_ not modelled 99.9 13 PDB header:ligase Chain: C: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine 26 c1woyA_ not modelled 99.9 22 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus 27 c2ct8A_ not modelled 99.9 16 PDB header:ligase/rna Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue 28 d1ivsa4 not modelled 99.9 18 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 29 d1rqga2 not modelled 99.9 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 30 c1pfuA_ not modelled 99.9 16 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate 31 c3kflA_ not modelled 99.9 14 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate 32 d1ilea3 not modelled 99.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 33 d1ffya3 not modelled 99.8 19 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 34 c1rqgA_ not modelled 99.8 20 PDB header:ligase Chain: A: PDB Molecule:methionyl-trna synthetase; PDBTitle: methionyl-trna synthetase from pyrococcus abyssi 35 d1irxa1 not modelled 99.8 12 Fold:An anticodon-binding domain of class I aminoacyl-tRNA synthetases Superfamily:An anticodon-binding domain of class I aminoacyl-tRNA synthetases Family:C-terminal domain of class I lysyl-tRNA synthetase 36 d1iq0a2 not modelled 99.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 37 d1h3na3 not modelled 99.8 22 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 38 c2zufA_ not modelled 99.7 22 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg) 39 c1gaxB_ not modelled 99.7 24 PDB header:ligase/rna Chain: B: PDB Molecule:valyl-trna synthetase; PDBTitle: crystal structure of thermus thermophilus valyl-trna2 synthetase complexed with trna(val) and valyl-adenylate3 analogue 40 c1ileA_ not modelled 99.7 23 PDB header:aminoacyl-trna synthetase Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: isoleucyl-trna synthetase 41 c1iq0A_ not modelled 99.6 16 PDB header:ligase Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: thermus thermophilus arginyl-trna synthetase 42 c1qu2A_ not modelled 99.6 20 PDB header:ligase/rna Chain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin 43 c1f7uA_ not modelled 99.6 22 PDB header:ligase/rna Chain: A: PDB Molecule:arginyl-trna synthetase; PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg 44 c1wz2B_ not modelled 99.6 28 PDB header:ligase/rna Chain: B: PDB Molecule:leucyl-trna synthetase; PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex 45 c1wkbA_ not modelled 99.5 29 PDB header:ligase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation 46 c1obhA_ not modelled 99.3 27 PDB header:synthetase Chain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site 47 c2g36A_ not modelled 99.0 23 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution 48 c2cybA_ not modelled 98.8 21 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus 49 c2j5bA_ not modelled 98.8 22 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol 50 c2el7A_ not modelled 98.6 19 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus 51 c2cyaA_ not modelled 98.5 18 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix 52 c3jxeB_ not modelled 98.5 14 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp 53 c3hzrD_ not modelled 98.5 16 PDB header:ligase Chain: D: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica 54 c3focB_ not modelled 98.5 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from giardia lamblia 55 c3a05A_ not modelled 98.4 21 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 hyperthermophilic archaeon, aeropyrum pernix k1 complex3 with tryptophan 56 c3m5wB_ not modelled 98.3 15 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni 57 c3prhB_ not modelled 98.3 20 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis 58 c2yy5C_ not modelled 98.1 16 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae 59 c2quiB_ not modelled 98.1 14 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp 60 c3p0jD_ not modelled 98.1 14 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1 61 d1i6la_ not modelled 98.1 15 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 62 c1yi8C_ not modelled 98.0 20 PDB header:ligase Chain: C: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp 63 c2cycB_ not modelled 97.9 17 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii 64 c2janD_ not modelled 97.8 16 PDB header:ligase Chain: D: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state 65 d1h3fa1 not modelled 97.8 17 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 66 c2ip1A_ not modelled 97.7 13 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase 67 d1r6ta2 not modelled 97.6 11 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 68 c2dlcX_ not modelled 97.6 14 PDB header:ligase/trna Chain: X: PDB Molecule:tyrosyl-trna synthetase, cytoplasmic; PDBTitle: crystal structure of the ternary complex of yeast tyrosyl-trna2 synthetase 69 c1h3eA_ not modelled 97.5 22 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol 70 d2ts1a_ not modelled 97.3 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 71 c2ts1A_ not modelled 97.3 14 PDB header:ligase (synthetase) Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: structure of tyrosyl-t/rna synthetase refined at 2.3 angstroms2 resolution. interaction of the enzyme with the tyrosyl adenylate3 intermediate 72 c1jiiA_ not modelled 97.3 14 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of s. aureus tyrrs in complex with sb-219383 73 d1jila_ not modelled 97.1 13 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 74 c1x8xA_ not modelled 97.0 17 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: tyrosyl t-rna synthetase from e.coli complexed with tyrosine 75 c3hv0A_ not modelled 96.9 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from cryptosporidium parvum 76 d1n3la_ not modelled 96.7 14 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 77 c3n9iA_ not modelled 96.4 17 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92 78 c3sz3A_ not modelled 96.1 15 PDB header:ligase Chain: A: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of tryptophanyl-trna synthetase from vibrio cholerae2 with an endogenous tryptophan 79 c1q11A_ not modelled 95.8 15 PDB header:ligase Chain: A: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol 80 c2rkjM_ not modelled 95.7 17 PDB header:ligase/rna Chain: M: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: cocrystal structure of a tyrosyl-trna synthetase splicing2 factor with a group i intron rna 81 d1j1ua_ not modelled 95.6 12 Fold:Adenine nucleotide alpha hydrolase-like Superfamily:Nucleotidylyl transferase Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain 82 c3i05B_ not modelled 95.4 8 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: tryptophanyl-trna synthetase from trypanosoma brucei 83 c1r6uB_ not modelled 92.9 10 PDB header:ligase Chain: B: PDB Molecule:tryptophanyl-trna synthetase; PDBTitle: crystal structure of an active fragment of human tryptophanyl-trna2 synthetase with cytokine activity 84 c2pidB_ not modelled 53.6 13 PDB header:ligase Chain: B: PDB Molecule:tyrosyl-trna synthetase; PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog 85 d2p10a1 not modelled 52.5 15 Fold:TIM beta/alpha-barrel Superfamily:Phosphoenolpyruvate/pyruvate domain Family:Mll9387-like 86 d1w7ca1 not modelled 36.9 17 Fold:Supersandwich Superfamily:Amine oxidase catalytic domain Family:Amine oxidase catalytic domain 87 c2p10D_ not modelled 35.6 15 PDB header:hydrolase Chain: D: PDB Molecule:mll9387 protein; PDBTitle: crystal structure of a putative phosphonopyruvate hydrolase (mll9387)2 from mesorhizobium loti maff303099 at 2.15 a resolution 88 d1d6za1 not modelled 35.2 33 Fold:Supersandwich Superfamily:Amine oxidase catalytic domain Family:Amine oxidase catalytic domain 89 c1n9eA_ not modelled 33.9 17 PDB header:oxidoreductase Chain: A: PDB Molecule:lysyl oxidase; PDBTitle: crystal structure of pichia pastoris lysyl oxidase pplo 90 c1lw7A_ not modelled 33.6 8 PDB header:transferase Chain: A: PDB Molecule:transcriptional regulator nadr; PDBTitle: nadr protein from haemophilus influenzae 91 c2pncB_ not modelled 33.3 22 PDB header:oxidoreductase Chain: B: PDB Molecule:copper amine oxidase, liver isozyme; PDBTitle: crystal structure of bovine plasma copper-containing amine oxidase in2 complex with clonidine 92 c1w7cA_ not modelled 33.0 17 PDB header:oxidoreductase Chain: A: PDB Molecule:lysyl oxidase; PDBTitle: pplo at 1.23 angstroms 93 c1h3oA_ not modelled 31.8 13 PDB header:transcription/tbp-associated factors Chain: A: PDB Molecule:transcription initiation factor tfiid 135 kda PDBTitle: crystal structure of the human taf4-taf122 (tafii135-tafii20) complex 94 d1h3oa_ not modelled 31.8 13 Fold:Histone-fold Superfamily:Histone-fold Family:TBP-associated factors, TAFs 95 d1w6ga1 not modelled 30.0 33 Fold:Supersandwich Superfamily:Amine oxidase catalytic domain Family:Amine oxidase catalytic domain 96 c1ui7A_ not modelled 29.9 33 PDB header:oxidoreductase Chain: A: PDB Molecule:phenylethylamine oxidase; PDBTitle: site-directed mutagenesis of his433 involved in binding of2 copper ion in arthrobacter globiformis amine oxidase 97 c1ksiA_ not modelled 29.4 33 PDB header:oxidoreductase Chain: A: PDB Molecule:copper amine oxidase; PDBTitle: crystal structure of a eukaryotic (pea seedling) copper-containing2 amine oxidase at 2.2a resolution 98 c3higB_ not modelled 28.9 22 PDB header:oxidoreductase Chain: B: PDB Molecule:amiloride-sensitive amine oxidase; PDBTitle: crystal structure of human diamine oxidase in complex with the2 inhibitor berenil 99 c1d6uB_ not modelled 26.8 33 PDB header:oxidoreductase Chain: B: PDB Molecule:copper amine oxidase; PDBTitle: crystal structure of e. coli amine oxidase anaerobically reduced with2 beta-phenylethylamine 100 c3pgbA_ not modelled 26.1 22 PDB header:oxidoreductase Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of aspergillus nidulans amine oxidase 101 c1ekmC_ not modelled 25.9 28 PDB header:oxidoreductase Chain: C: PDB Molecule:copper amine oxidase; PDBTitle: crystal structure at 2.5 a resolution of zinc-substituted2 copper amine oxidase of hansenula polymorpha expressed in3 escherichia coli 102 c3loyB_ not modelled 25.7 33 PDB header:oxidoreductase Chain: B: PDB Molecule:copper amine oxidase; PDBTitle: crystal structure of a copper-containing benzylamine oxidase from2 hansenula polymorpha 103 d2oqea1 not modelled 25.1 28 Fold:Supersandwich Superfamily:Amine oxidase catalytic domain Family:Amine oxidase catalytic domain 104 d1w2za1 not modelled 24.6 33 Fold:Supersandwich Superfamily:Amine oxidase catalytic domain Family:Amine oxidase catalytic domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0