Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP75783
DateThu Jan 5 12:14:05 GMT 2012
Unique Job ID785c43833a7cfdad

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2vv5D_
Top template information
PDB header:membrane protein
Chain: D: PDB Molecule:small-conductance mechanosensitive channel;
PDBTitle: the open structure of mscs
Confidence and coverage
Confidence:100.0% Coverage: 33%
246 residues ( 33% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDT
Secondary structure 



























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Disorder  ??















???????????????????????????










?


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   .........70.........80.........90.........100.........110.........120
Sequence  SRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEVSRHYGEALSARFGQLYRN
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?????????????????





























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   .........130.........140.........150.........160.........170.........180
Sequence  ITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCALPLYRKMGQWARQKNRERSNW
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Disorder 


???????





































????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  LQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVL
Secondary structure 





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?
???
??





















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   .........250.........260.........270.........280.........290.........300
Sequence  RLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIGYGLIVAVPIISNQVNVQIGALANV
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??????







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   .........310.........320.........330.........340.........350.........360
Sequence  IIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFF
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?????????
























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   .........370.........380.........390.........400.........410.........420
Sequence  FSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAKTITLSPHTQRNYPELQKRLN
Secondary structure 


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????
???
??





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   .........430.........440.........450.........460.........470.........480
Sequence  GWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVG
Secondary structure 

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?
























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   .........490.........500.........510.........520.........530.........540
Sequence  WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPL
Secondary structure 






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???????
?



























???




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   .........550.........560.........570.........580.........590.........600
Sequence  LAGAGALGLAISFGSQTLVKDIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVR
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   .........610.........620.........630.........640.........650.........660
Sequence  QDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDADKANQALKDAVAELMENEEIR
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??
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   .........670.........680.........690.........700.........710.........720
Sequence  GLIIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY
Secondary structure 



















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Disorder 
?

























































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   .........730.........740.
Sequence  QVLPAPGATPAEPLPPGEPTL
Secondary structure 
















SS confidence 




















Disorder 



?
???????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 2vv5 chain D

3D model

Region: 466 - 725
Aligned: 246
Modelled: 260
Confidence: 100.0%
Identity: 20%
PDB header:membrane protein
Chain: D: PDB Molecule:small-conductance mechanosensitive channel;
PDBTitle: the open structure of mscs

Phyre2

PDB 2vv5 chain A domain 2

3D model

Region: 622 - 726
Aligned: 99
Modelled: 105
Confidence: 99.4%
Identity: 16%
Fold: Ferredoxin-like
Superfamily: Mechanosensitive channel protein MscS (YggB), C-terminal domain
Family: Mechanosensitive channel protein MscS (YggB), C-terminal domain

Phyre2

PDB 2vv5 chain A domain 1

3D model

Region: 558 - 621
Aligned: 64
Modelled: 64
Confidence: 99.0%
Identity: 28%
Fold: Sm-like fold
Superfamily: Sm-like ribonucleoproteins
Family: Mechanosensitive channel protein MscS (YggB), middle domain

Phyre2

PDB 2vv5 chain A domain 3

3D model

Region: 466 - 556
Aligned: 83
Modelled: 91
Confidence: 98.2%
Identity: 19%
Fold: Mechanosensitive channel protein MscS (YggB), transmembrane region
Superfamily: Mechanosensitive channel protein MscS (YggB), transmembrane region
Family: Mechanosensitive channel protein MscS (YggB), transmembrane region

Phyre2

PDB 2e6z chain A

3D model

Region: 571 - 614
Aligned: 44
Modelled: 44
Confidence: 78.1%
Identity: 16%
PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt5;
PDBTitle: solution structure of the second kow motif of human2 transcription elongation factor spt5

Phyre2

PDB 1nz9 chain A

3D model

Region: 573 - 593
Aligned: 21
Modelled: 21
Confidence: 77.8%
Identity: 33%
Fold: SH3-like barrel
Superfamily: Translation proteins SH3-like domain
Family: N-utilization substance G protein NusG, C-terminal domain

Phyre2

PDB 2vfy chain A

3D model

Region: 626 - 722
Aligned: 90
Modelled: 97
Confidence: 77.5%
Identity: 13%
PDB header:hydrolase
Chain: A: PDB Molecule:akap18 delta;
PDBTitle: akap18 delta central domain

Phyre2

PDB 2kvq chain G

3D model

Region: 571 - 593
Aligned: 23
Modelled: 23
Confidence: 76.9%
Identity: 22%
PDB header:transcription
Chain: G: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: solution structure of nuse:nusg-ctd complex

Phyre2

PDB 2jvv chain A

3D model

Region: 571 - 593
Aligned: 23
Modelled: 23
Confidence: 76.9%
Identity: 22%
PDB header:transcription
Chain: A: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: solution structure of e. coli nusg carboxyterminal domain

Phyre2

PDB 1npp chain A domain 2

3D model

Region: 573 - 593
Aligned: 21
Modelled: 21
Confidence: 76.4%
Identity: 43%
Fold: SH3-like barrel
Superfamily: Translation proteins SH3-like domain
Family: N-utilization substance G protein NusG, C-terminal domain

Phyre2

PDB 2hqh chain A domain 1

3D model

Region: 573 - 593
Aligned: 21
Modelled: 21
Confidence: 75.6%
Identity: 29%
Fold: SH3-like barrel
Superfamily: Cap-Gly domain
Family: Cap-Gly domain

Phyre2

PDB 2dfa chain A domain 1

3D model

Region: 637 - 717
Aligned: 60
Modelled: 64
Confidence: 75.2%
Identity: 23%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: LamB/YcsF-like

Phyre2

PDB 2zkr chain T

3D model

Region: 573 - 610
Aligned: 38
Modelled: 38
Confidence: 71.8%
Identity: 16%
PDB header:ribosomal protein/rna
Chain: T: PDB Molecule:rna expansion segment es39 part iii;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map

Phyre2

PDB 3p8b chain B

3D model

Region: 574 - 618
Aligned: 45
Modelled: 45
Confidence: 69.9%
Identity: 20%
PDB header:transferase/transcription
Chain: B: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: x-ray crystal structure of pyrococcus furiosus transcription2 elongation factor spt4/5

Phyre2

PDB 2cqa chain A domain 1

3D model

Region: 569 - 593
Aligned: 25
Modelled: 25
Confidence: 69.0%
Identity: 24%
Fold: OB-fold
Superfamily: Nucleic acid-binding proteins
Family: TIP49 domain

Phyre2

PDB 1v6t chain A

3D model

Region: 637 - 720
Aligned: 66
Modelled: 67
Confidence: 68.2%
Identity: 18%
Fold: 7-stranded beta/alpha barrel
Superfamily: Glycoside hydrolase/deacetylase
Family: LamB/YcsF-like

Phyre2

PDB 2cp6 chain A domain 1

3D model

Region: 571 - 593
Aligned: 23
Modelled: 23
Confidence: 66.4%
Identity: 30%
Fold: SH3-like barrel
Superfamily: Cap-Gly domain
Family: Cap-Gly domain

Phyre2

PDB 1oy8 chain A

3D model

Region: 612 - 710
Aligned: 96
Modelled: 99
Confidence: 65.8%
Identity: 13%
PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump

Phyre2

PDB 2d5w chain A

3D model

Region: 634 - 715
Aligned: 68
Modelled: 82
Confidence: 65.5%
Identity: 15%
PDB header:peptide binding protein
Chain: A: PDB Molecule:peptide abc transporter, peptide-binding protein;
PDBTitle: the crystal structure of oligopeptide binding protein from thermus2 thermophilus hb8 complexed with pentapeptide

Phyre2

PDB 1t9h chain A domain 1

3D model

Region: 576 - 596
Aligned: 21
Modelled: 21
Confidence: 64.3%
Identity: 24%
Fold: OB-fold
Superfamily: Nucleic acid-binding proteins
Family: Cold shock DNA-binding domain-like

Phyre2
1

c2vv5D_
2

d2vv5a2
3

d2vv5a1
4

d2vv5a3
5

c2e6zA_
6

d1nz9a_
7

c2vfyA_
8

c2kvqG_
9

c2jvvA_
10

d1nppa2
11

d2hqha1
12

d2dfaa1
13

c2zkrt_
14

c3p8bB_
15

d2cqaa1
16

d1v6ta_
17

d2cp6a1
18

c1oy8A_
19

c2d5wA_
20

d1t9ha1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c2vv5D_



100.0 20 PDB header:membrane protein
Chain: D: PDB Molecule:small-conductance mechanosensitive channel;
PDBTitle: the open structure of mscs
2d2vv5a2



99.4 16 Fold:Ferredoxin-like
Superfamily:Mechanosensitive channel protein MscS (YggB), C-terminal domain
Family:Mechanosensitive channel protein MscS (YggB), C-terminal domain
3d2vv5a1



99.0 28 Fold:Sm-like fold
Superfamily:Sm-like ribonucleoproteins
Family:Mechanosensitive channel protein MscS (YggB), middle domain
4d2vv5a3



98.2 19 Fold:Mechanosensitive channel protein MscS (YggB), transmembrane region
Superfamily:Mechanosensitive channel protein MscS (YggB), transmembrane region
Family:Mechanosensitive channel protein MscS (YggB), transmembrane region
5c2e6zA_



78.1 16 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt5;
PDBTitle: solution structure of the second kow motif of human2 transcription elongation factor spt5
6d1nz9a_



77.8 33 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:N-utilization substance G protein NusG, C-terminal domain
7c2vfyA_



77.5 13 PDB header:hydrolase
Chain: A: PDB Molecule:akap18 delta;
PDBTitle: akap18 delta central domain
8c2kvqG_



76.9 22 PDB header:transcription
Chain: G: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: solution structure of nuse:nusg-ctd complex
9c2jvvA_



76.9 22 PDB header:transcription
Chain: A: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: solution structure of e. coli nusg carboxyterminal domain
10d1nppa2



76.4 43 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:N-utilization substance G protein NusG, C-terminal domain
11d2hqha1



75.6 29 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
12d2dfaa1



75.2 23 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
13c2zkrt_



71.8 16 PDB header:ribosomal protein/rna
Chain: T: PDB Molecule:rna expansion segment es39 part iii;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
14c3p8bB_



69.9 20 PDB header:transferase/transcription
Chain: B: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: x-ray crystal structure of pyrococcus furiosus transcription2 elongation factor spt4/5
15d2cqaa1



69.0 24 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:TIP49 domain
16d1v6ta_



68.2 18 Fold:7-stranded beta/alpha barrel
Superfamily:Glycoside hydrolase/deacetylase
Family:LamB/YcsF-like
17d2cp6a1



66.4 30 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
18c1oy8A_



65.8 13 PDB header:membrane protein
Chain: A: PDB Molecule:acriflavine resistance protein b;
PDBTitle: structural basis of multiple drug binding capacity of the acrb2 multidrug efflux pump
19c2d5wA_



65.5 15 PDB header:peptide binding protein
Chain: A: PDB Molecule:peptide abc transporter, peptide-binding protein;
PDBTitle: the crystal structure of oligopeptide binding protein from thermus2 thermophilus hb8 complexed with pentapeptide
20d1t9ha1



64.3 24 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
21d1u0la1



not modelled 63.0 25 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Cold shock DNA-binding domain-like
22c2x5cB_



not modelled 62.8 21 PDB header:viral protein
Chain: B: PDB Molecule:hypothetical protein orf131;
PDBTitle: crystal structure of hypothetical protein orf131 from2 pyrobaculum spherical virus
23c3ftjA_



not modelled 60.3 18 PDB header:hydrolase
Chain: A: PDB Molecule:macrolide export atp-binding/permease protein
PDBTitle: crystal structure of the periplasmic region of macb from2 actinobacillus actinomycetemcomitans
24d1whka_



not modelled 59.7 17 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
25c3ry3B_



not modelled 58.1 20 PDB header:transport protein
Chain: B: PDB Molecule:putative solute-binding protein;
PDBTitle: putative solute-binding protein from yersinia pestis.
26d1vqot1



not modelled 55.9 30 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:Ribosomal proteins L24p and L21e
27d1h6za2



not modelled 55.0 26 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:Phosphohistidine domain
Family:Pyruvate phosphate dikinase, central domain
28c3pamB_



not modelled 54.5 18 PDB header:transport protein
Chain: B: PDB Molecule:transmembrane protein;
PDBTitle: crystal structure of a domain of transmembrane protein of abc-type2 oligopeptide transport system from bartonella henselae str. houston-1
29c2rcnA_



not modelled 54.3 31 PDB header:hydrolase
Chain: A: PDB Molecule:probable gtpase engc;
PDBTitle: crystal structure of the ribosomal interacting gtpase yjeq from the2 enterobacterial species salmonella typhimurium.
30c4a1cS_



not modelled 53.1 25 PDB header:ribosome
Chain: S: PDB Molecule:rpl26;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 4.
31d1vqoq1



not modelled 52.7 30 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:Ribosomal proteins L24p and L21e
32d2coya1



not modelled 51.6 23 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
33d1whma_



not modelled 51.5 18 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
34d2p13a1



not modelled 51.0 13 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
35d1whja_



not modelled 50.5 33 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
36c1t9hA_



not modelled 50.4 21 PDB header:hydrolase
Chain: A: PDB Molecule:probable gtpase engc;
PDBTitle: the crystal structure of yloq, a circularly permuted gtpase.
37d2do3a1



not modelled 50.2 19 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:SPT5 KOW domain-like
38d2e3ia1



not modelled 50.2 15 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
39d2cp5a1



not modelled 50.1 14 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
40d2cp2a1



not modelled 48.8 25 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
41c2e4hA_



not modelled 48.8 27 PDB header:structural protein
Chain: A: PDB Molecule:restin;
PDBTitle: solution structure of cytoskeletal protein in complex with2 tubulin tail
42d2plsa1



not modelled 48.6 20 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
43c1m1gB_



not modelled 48.3 43 PDB header:transcription
Chain: B: PDB Molecule:transcription antitermination protein nusg;
PDBTitle: crystal structure of aquifex aeolicus n-utilization2 substance g (nusg), space group p2(1)
44c2z0wA_



not modelled 48.1 20 PDB header:protein binding
Chain: A: PDB Molecule:cap-gly domain-containing linker protein 4;
PDBTitle: crystal structure of the 2nd cap-gly domain in human restin-2 like protein 2 reveals a swapped-dimer
45d1khia1



not modelled 47.1 23 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:eIF5a N-terminal domain-like
46d2o1ra1



not modelled 47.0 14 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
47d2coza1



not modelled 47.0 27 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
48d1bkba1



not modelled 46.9 21 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:eIF5a N-terminal domain-like
49d2e3ha1



not modelled 46.9 30 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
50d1ppje2



not modelled 46.7 4 Fold:Single transmembrane helix
Superfamily:ISP transmembrane anchor
Family:ISP transmembrane anchor
51c3nkuA_



not modelled 45.9 28 PDB header:protein transport
Chain: A: PDB Molecule:drra;
PDBTitle: crystal structure of the n-terminal domain of drra/sidm from2 legionella pneumophila
52c2omdB_



not modelled 45.7 13 PDB header:lyase
Chain: B: PDB Molecule:molybdopterin-converting factor subunit 2;
PDBTitle: crystal structure of molybdopterin converting factor subunit 22 (aq_2181) from aquifex aeolicus vf5
53c2jxfA_



not modelled 45.1 18 PDB header:viral protein, membrane protein
Chain: A: PDB Molecule:genome polyprotein;
PDBTitle: the solution structure of hcv ns4b(40-69)
54c3iz5Y_



not modelled 45.1 19 PDB header:ribosome
Chain: Y: PDB Molecule:60s ribosomal protein l26 (l24p);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
55c3ftoA_



not modelled 45.1 16 PDB header:peptide binding protein
Chain: A: PDB Molecule:oligopeptide-binding protein oppa;
PDBTitle: crystal structure of oppa in a open conformation
56d1dpea_



not modelled 44.9 25 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
57c2qieA_



not modelled 44.8 16 PDB header:transferase
Chain: A: PDB Molecule:molybdopterin-converting factor subunit 2;
PDBTitle: staphylococcus aureus molybdopterin synthase in complex2 with precursor z
58c2grvC_



not modelled 44.6 17 PDB header:biosynthetic protein
Chain: C: PDB Molecule:lpqw;
PDBTitle: crystal structure of lpqw
59d1kbla2



not modelled 44.5 19 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:Phosphohistidine domain
Family:Pyruvate phosphate dikinase, central domain
60d1iuha_



not modelled 44.3 12 Fold:LigT-like
Superfamily:LigT-like
Family:2'-5' RNA ligase LigT
61c3tpaA_



not modelled 44.2 14 PDB header:heme binding protein
Chain: A: PDB Molecule:heme-binding protein a;
PDBTitle: structure of hbpa2 from haemophilus parasuis
62d1iz6a1



not modelled 43.4 17 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:eIF5a N-terminal domain-like
63d1u7ka_



not modelled 43.2 20 Fold:Retrovirus capsid protein, N-terminal core domain
Superfamily:Retrovirus capsid protein, N-terminal core domain
Family:Retrovirus capsid protein, N-terminal core domain
64d1s04a_



not modelled 43.2 18 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:ProFAR isomerase associated domain
65d2cowa1



not modelled 43.1 32 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
66c1u0lB_



not modelled 42.8 25 PDB header:hydrolase
Chain: B: PDB Molecule:probable gtpase engc;
PDBTitle: crystal structure of yjeq from thermotoga maritima
67d1iwga1



not modelled 42.4 16 Fold:Ferredoxin-like
Superfamily:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
Family:Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
68d1xoca1



not modelled 42.3 20 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
69d2cp0a1



not modelled 42.0 31 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
70c2wctC_



not modelled 41.9 32 PDB header:rna-binding protein
Chain: C: PDB Molecule:non-structural protein 3;
PDBTitle: human sars coronavirus unique domain (triclinic form)
71d1vbga2



not modelled 41.0 19 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:Phosphohistidine domain
Family:Pyruvate phosphate dikinase, central domain
72c3dedB_



not modelled 40.9 13 PDB header:membrane protein
Chain: B: PDB Molecule:probable hemolysin;
PDBTitle: c-terminal domain of probable hemolysin from chromobacterium violaceum
73d1vr5a1



not modelled 40.9 12 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
74c3lvuB_



not modelled 40.4 17 PDB header:transport protein
Chain: B: PDB Molecule:abc transporter, periplasmic substrate-binding protein;
PDBTitle: crystal structure of abc transporter, periplasmic substrate-binding2 protein spo2066 from silicibacter pomeroyi
75c3iz5U_



not modelled 40.3 34 PDB header:ribosome
Chain: U: PDB Molecule:60s ribosomal protein l21 (l21e);
PDBTitle: localization of the large subunit ribosomal proteins into a 5.5 a2 cryo-em map of triticum aestivum translating 80s ribosome
76c2o7jA_



not modelled 40.0 18 PDB header:sugar binding protein
Chain: A: PDB Molecule:oligopeptide abc transporter, periplasmic
PDBTitle: the x-ray crystal structure of a thermophilic cellobiose2 binding protein bound with cellopentaose
77c4a1aP_



not modelled 39.6 41 PDB header:ribosome
Chain: P: PDB Molecule:60s ribosomal protein l21;
PDBTitle: t.thermophila 60s ribosomal subunit in complex with2 initiation factor 6. this file contains 5s rrna,3 5.8s rrna and proteins of molecule 3.
78d2cp3a1



not modelled 39.6 35 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
79d2eyqa1



not modelled 39.6 16 Fold:SH3-like barrel
Superfamily:CarD-like
Family:CarD-like
80d3deda1



not modelled 39.6 13 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
81d1whha_



not modelled 39.3 22 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
82d1xnea_



not modelled 39.2 15 Fold:PUA domain-like
Superfamily:PUA domain-like
Family:ProFAR isomerase associated domain
83c2e70A_



not modelled 39.2 20 PDB header:transcription
Chain: A: PDB Molecule:transcription elongation factor spt5;
PDBTitle: solution structure of the fifth kow motif of human2 transcription elongation factor spt5
84c1ztyA_



not modelled 39.0 14 PDB header:sugar binding protein, signaling protein
Chain: A: PDB Molecule:chitin oligosaccharide binding protein;
PDBTitle: crystal structure of the chitin oligasaccharide binding2 protein
85d2nqwa1



not modelled 39.0 19 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
86d1m9dc_



not modelled 38.9 21 Fold:Retrovirus capsid protein, N-terminal core domain
Superfamily:Retrovirus capsid protein, N-terminal core domain
Family:Retrovirus capsid protein, N-terminal core domain
87d2eifa1



not modelled 38.7 17 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:eIF5a N-terminal domain-like
88d1v6ga2



not modelled 37.9 27 Fold:Glucocorticoid receptor-like (DNA-binding domain)
Superfamily:Glucocorticoid receptor-like (DNA-binding domain)
Family:LIM domain
89d1yvca1



not modelled 37.7 15 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:TRAM domain
90d1e32a3



not modelled 37.7 18 Fold:Cdc48 domain 2-like
Superfamily:Cdc48 domain 2-like
Family:Cdc48 domain 2-like
91c3llbA_



not modelled 37.2 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:uncharacterized protein;
PDBTitle: the crystal structure of the protein pa3983 with unknown2 function from pseudomonas aeruginosa pao1
92d1m9fd_



not modelled 37.0 15 Fold:Retrovirus capsid protein, N-terminal core domain
Superfamily:Retrovirus capsid protein, N-terminal core domain
Family:Retrovirus capsid protein, N-terminal core domain
93c2yv5A_



not modelled 36.6 16 PDB header:hydrolase
Chain: A: PDB Molecule:yjeq protein;
PDBTitle: crystal structure of yjeq from aquifex aeolicus
94d1bbua1



not modelled 36.4 20 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Anticodon-binding domain
95d1zyma2



not modelled 35.8 13 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:Phosphohistidine domain
Family:N-terminal domain of enzyme I of the PEP:sugar phosphotransferase system
96d2pxrc1



not modelled 35.5 17 Fold:Retrovirus capsid protein, N-terminal core domain
Superfamily:Retrovirus capsid protein, N-terminal core domain
Family:Retrovirus capsid protein, N-terminal core domain
97d1bcce2



not modelled 34.4 9 Fold:Single transmembrane helix
Superfamily:ISP transmembrane anchor
Family:ISP transmembrane anchor
98c2ivwA_



not modelled 34.4 20 PDB header:lipoprotein
Chain: A: PDB Molecule:pilp pilot protein;
PDBTitle: the solution structure of a domain from the neisseria2 meningitidis pilp pilot protein.
99c2fb0A_



not modelled 34.3 14 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein;
PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase
100d1zlqa1



not modelled 34.2 20 Fold:Periplasmic binding protein-like II
Superfamily:Periplasmic binding protein-like II
Family:Phosphate binding protein-like
101c2zkrq_



not modelled 33.8 31 PDB header:ribosomal protein/rna
Chain: Q: PDB Molecule:rna expansion segment es31 part ii;
PDBTitle: structure of a mammalian ribosomal 60s subunit within an2 80s complex obtained by docking homology models of the rna3 and proteins into an 8.7 a cryo-em map
102c3t66A_



not modelled 33.5 13 PDB header:transport protein
Chain: A: PDB Molecule:nickel abc transporter (nickel-binding protein);
PDBTitle: crystal structure of nickel abc transporter from bacillus halodurans
103d1x6oa1



not modelled 33.4 17 Fold:SH3-like barrel
Superfamily:Translation proteins SH3-like domain
Family:eIF5a N-terminal domain-like
104d1vgya2



not modelled 33.3 17 Fold:Ferredoxin-like
Superfamily:Bacterial exopeptidase dimerisation domain
Family:Bacterial exopeptidase dimerisation domain
105d1q40b_



not modelled 33.2 26 Fold:Cystatin-like
Superfamily:NTF2-like
Family:NTF2-like
106d1g7sa1



not modelled 33.1 5 Fold:Reductase/isomerase/elongation factor common domain
Superfamily:Translation proteins
Family:Elongation factors
107d1c99a_



not modelled 32.8 39 Fold:Transmembrane helix hairpin
Superfamily:F1F0 ATP synthase subunit C
Family:F1F0 ATP synthase subunit C
108c3c5oD_



not modelled 32.5 18 PDB header:structural genomics, unknown function
Chain: D: PDB Molecule:upf0311 protein rpa1785;
PDBTitle: crystal structure of the conserved protein of unknown function rpa17852 from rhodopseudomonas palustris
109c1l6nA_



not modelled 32.4 18 PDB header:viral protein
Chain: A: PDB Molecule:gag polyprotein;
PDBTitle: structure of the n-terminal 283-residue fragment of the hiv-2 1 gag polyprotein
110d2plia1



not modelled 32.4 39 Fold:FAD-binding/transporter-associated domain-like
Superfamily:FAD-binding/transporter-associated domain-like
Family:CorC/HlyC domain-like
111c2l66B_



not modelled 31.8 32 PDB header:transcription regulator
Chain: B: PDB Molecule:transcriptional regulator, abrb family;
PDBTitle: the dna-recognition fold of sso7c4 suggests a new member of spovt-abrb2 superfamily from archaea.
112d1yeza1



not modelled 31.8 10 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:TRAM domain
113c2lc4A_



not modelled 31.8 28 PDB header:structural protein
Chain: A: PDB Molecule:pilp protein;
PDBTitle: solution structure of pilp from pseudomonas aeruginosa
114c1s1iQ_



not modelled 31.4 31 PDB header:ribosome
Chain: Q: PDB Molecule:60s ribosomal protein l21-a;
PDBTitle: structure of the ribosomal 80s-eef2-sordarin complex from2 yeast obtained by docking atomic models for rna and protein3 components into a 11.7 a cryo-em map. this file, 1s1i,4 contains 60s subunit. the 40s ribosomal subunit is in file5 1s1h.
115d2hi6a1



not modelled 31.2 41 Fold:The "swivelling" beta/beta/alpha domain
Superfamily:LeuD/IlvD-like
Family:AF0055-like
116d1ixda_



not modelled 31.2 17 Fold:SH3-like barrel
Superfamily:Cap-Gly domain
Family:Cap-Gly domain
117d2if6a1



not modelled 31.0 21 Fold:Cysteine proteinases
Superfamily:Cysteine proteinases
Family:YiiX-like
118d3d3ra1



not modelled 30.8 25 Fold:OB-fold
Superfamily:HupF/HypC-like
Family:HupF/HypC-like
119d2a7ya1



not modelled 30.0 19 Fold:SH3-like barrel
Superfamily:Cell growth inhibitor/plasmid maintenance toxic component
Family:Rv2302-like
120c2a7yA_



not modelled 30.0 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:hypothetical protein rv2302/mt2359;
PDBTitle: solution structure of the conserved hypothetical protein2 rv2302 from the bacterium mycobacterium tuberculosis

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0