PHYRE Protein Fold Recognition Server

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Protein Homology/analogY Recognition Engine V 2.0

Fold library entry viewer: c1oy8A_

Fold library id	PDB Header	Molecule	Title
c1oy8A_	PDB header: membrane protein	Chain: A: PDB Molecule: acriflavine resistance protein b;	PDBTitle: structural basis of multiple drug binding capacity of the2 acrb multidrug efflux pump

Links to external resources
Added to library: Tue Mar 16 14:18:40 2010

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60 . . . . . . . . . 70

Sequence D R P I F A W V I A I I I M L A G G L A I L K L P V A Q Y P T I A P P A V T I S A S Y P G A D A K T V Q D T V T Q V I E Q N M N G I D N L M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S S
S
T T
T T
S S

. . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120 . . . . . . . . . 130 . . . . . . . . . 140

Sequence Y M S S N S D S T G T V Q I T L T F E S G T D A D I A Q V Q V Q N K L Q L A M P L L P Q E V Q Q Q G V S V E K S S S S F L M V V G V I N T D

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
T T
T T T G G G S
T S
S S

. . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180 . . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210

Sequence G T M T Q E D I S D Y V A A N M K D A I S R T S G V G D V Q L F G S Q Y A M R I W M N P N E L N K F Q L T P V D V I T A I K A Q N A Q V A A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S
T T T T T T T T T T S S
T T T
S

. . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240 . . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280

Sequence G Q L G G T P P V K G Q Q L N A S I I A Q T R L T S T E E F G K I L L K V N Q D G S R V L L R D V A K I E L G G E N Y D I I A E F N G Q P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
S
S S
T T
S T
T T T S
S
T T

. . . . . . . . . 290 . . . . . . . . . 300 . . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350

Sequence S G L G I K L A T G A N A L D T A A A I R A E L A K M E P F F P S G L K I V Y P Y D T T P F V K I S I H E V V K T L V E A I I L V F L V M Y

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T
T S
S
S S T T T S S S
S S
S B S

. . . . . . . . . 360 . . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence L F L Q N F R A T L I P T I A V P V V L L G T F A V L A A F G F S I N T L T M F G M V L A I G L L V D D A I V V V E N V E R V M A E E G L P

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T T T T T T T T T T
S
T

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480 . . . . . . . . . 490

Sequence P K E A T R K S M G Q I Q G A L V G I A M V L S A V F V P M A F F G G S T G A I Y R Q F S I T I V S A M A L S V L V A L I L T P A L C A T M

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S T T T T S T T T T
G G G T T T S

. . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540 . . . . . . . . . 550 . . . . . . . . . 560

Sequence L K F G W F N R M F E K S T H H Y T D S V G G I L R S T G R Y L V L Y L I I V V G M A Y L F V R L P S S F L P D E D Q G V F M T M V Q L P A

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
S S
B
S S
S
T

. . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600 . . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630

Sequence G A T Q E R T Q K V L N E V T H Y Y L T K E K N N V E S V F A V N G F G F A G R G Q N T G I A F V S L K D W A D R P G E E N K V E A I T M R

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T
T S
T T T
S S
G G G
S S T T S

. . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660 . . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700

Sequence A T R A F S Q I K D A M V F A F N L P A I V E L G T A T G F D F E L I D Q A G L G H E K L T Q A R N Q L L A E A A K H P M L T S V R P N G L

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T S
S S
B
S S
S S
S S
S S
S

. . . . . . . . . 710 . . . . . . . . . 720 . . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770

Sequence E D T P Q F K I D I D Q E K A Q A L G V S I N D I N T T L G A A W G G S Y V N D F I D R G R V K K V Y V M S E A K Y R M L P D D I G D W Y V

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T
T
T T
G G G S S S G G G G G G

. . . . . . . . . 780 . . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence R A A D G Q M V P F S A F S S S R W E Y G S P R L E R Y N G L P S M E I L G Q A A P G K S T G E A M E L M E Q L A S K L P T G V G Y D W S G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP)
T T S
S T T
S S S
T T S
T T

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900 . . . . . . . . . 910

Sequence N Q A P S L Y A I S L I V V F L C L A A L Y E S W S I P F S V M L V V P L G V I G A L L A A T F R G L T N D V Y F Q V G L L T T I G L S A K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T T T S S
S S S G G G T G G G S S
B

. . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960 . . . . . . . . . 970 . . . . . . . . . 980

Sequence N A I L I V E F A K D L M D K E G K G L I E A T L D A V R M R L R P I L M T S L A F I L G V M P L V I S T G A G S G A Q N A V G T G V M G G

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) S S S
T T T T T T S T T
S S
S

. . . . . . . . . 990 . . . . . . . . . 1000 . . . . . .

Sequence M V T A T V L A I F F V P V F F V V V R R R F S R K

Predicted secondary structure

SS confidence

Known secondary structure (DSSP) T S S S S S S T T T

Download: PDB structure FASTA sequence
Hidden Markov model

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Kelley LA et al. Nature Protocols 10, 845-858 (2015) [paper] [Citation link]

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Michael Sternberg

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	1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70
Sequence	D	R	P	I	F	A	W	V	I	A	I	I	I	M	L	A	G	G	L	A	I	L	K	L	P	V	A	Q	Y	P	T	I	A	P	P	A	V	T	I	S	A	S	Y	P	G	A	D	A	K	T	V	Q	D	T	V	T	Q	V	I	E	Q	N	M	N	G	I	D	N	L	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																						T	T	S				S	S				S											T	T										T							T					S	S
	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
Sequence	Y	M	S	S	N	S	D	S	T	G	T	V	Q	I	T	L	T	F	E	S	G	T	D	A	D	I	A	Q	V	Q	V	Q	N	K	L	Q	L	A	M	P	L	L	P	Q	E	V	Q	Q	Q	G	V	S	V	E	K	S	S	S	S	F	L	M	V	V	G	V	I	N	T	D
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)								T	T	S										T	T															T	T	T	G	G	G	S						T	S																				S	S
	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210
Sequence	G	T	M	T	Q	E	D	I	S	D	Y	V	A	A	N	M	K	D	A	I	S	R	T	S	G	V	G	D	V	Q	L	F	G	S	Q	Y	A	M	R	I	W	M	N	P	N	E	L	N	K	F	Q	L	T	P	V	D	V	I	T	A	I	K	A	Q	N	A	Q	V	A	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S				T	T								T	T	T					T	T	T	T	T							S	S																T	T	T														S
	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Sequence	G	Q	L	G	G	T	P	P	V	K	G	Q	Q	L	N	A	S	I	I	A	Q	T	R	L	T	S	T	E	E	F	G	K	I	L	L	K	V	N	Q	D	G	S	R	V	L	L	R	D	V	A	K	I	E	L	G	G	E	N	Y	D	I	I	A	E	F	N	G	Q	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)				S		S	S			T	T															S						T							T	T	T																S			S						T	T
	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350
Sequence	S	G	L	G	I	K	L	A	T	G	A	N	A	L	D	T	A	A	A	I	R	A	E	L	A	K	M	E	P	F	F	P	S	G	L	K	I	V	Y	P	Y	D	T	T	P	F	V	K	I	S	I	H	E	V	V	K	T	L	V	E	A	I	I	L	V	F	L	V	M	Y
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	T			T					S			S		S	S	T	T	T	S	S	S			S	S							S	B	S
	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence	L	F	L	Q	N	F	R	A	T	L	I	P	T	I	A	V	P	V	V	L	L	G	T	F	A	V	L	A	A	F	G	F	S	I	N	T	L	T	M	F	G	M	V	L	A	I	G	L	L	V	D	D	A	I	V	V	V	E	N	V	E	R	V	M	A	E	E	G	L	P
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	T	T	T	T	T	T	T	T																T			S																																	T
	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490
Sequence	P	K	E	A	T	R	K	S	M	G	Q	I	Q	G	A	L	V	G	I	A	M	V	L	S	A	V	F	V	P	M	A	F	F	G	G	S	T	G	A	I	Y	R	Q	F	S	I	T	I	V	S	A	M	A	L	S	V	L	V	A	L	I	L	T	P	A	L	C	A	T	M
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	S							T																T	T	T	S	T	T	T	T				G	G	G																						T	T	T									S
	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
Sequence	L	K	F	G	W	F	N	R	M	F	E	K	S	T	H	H	Y	T	D	S	V	G	G	I	L	R	S	T	G	R	Y	L	V	L	Y	L	I	I	V	V	G	M	A	Y	L	F	V	R	L	P	S	S	F	L	P	D	E	D	Q	G	V	F	M	T	M	V	Q	L	P	A
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)															T																																	S	S		B		S	S						S										T
	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630
Sequence	G	A	T	Q	E	R	T	Q	K	V	L	N	E	V	T	H	Y	Y	L	T	K	E	K	N	N	V	E	S	V	F	A	V	N	G	F	G	F	A	G	R	G	Q	N	T	G	I	A	F	V	S	L	K	D	W	A	D	R	P	G	E	E	N	K	V	E	A	I	T	M	R
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																			T	S		T	T	T												S	S																G	G	G			S	S	T	T	S
	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700
Sequence	A	T	R	A	F	S	Q	I	K	D	A	M	V	F	A	F	N	L	P	A	I	V	E	L	G	T	A	T	G	F	D	F	E	L	I	D	Q	A	G	L	G	H	E	K	L	T	Q	A	R	N	Q	L	L	A	E	A	A	K	H	P	M	L	T	S	V	R	P	N	G	L
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)						T	T	S		S	S					B				S	S		S	S			S	S										S	S																														S
	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770
Sequence	E	D	T	P	Q	F	K	I	D	I	D	Q	E	K	A	Q	A	L	G	V	S	I	N	D	I	N	T	T	L	G	A	A	W	G	G	S	Y	V	N	D	F	I	D	R	G	R	V	K	K	V	Y	V	M	S	E	A	K	Y	R	M	L	P	D	D	I	G	D	W	Y	V
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)																			T															T										T	T											G	G	G	S	S	S	G	G	G	G	G	G
	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840
Sequence	R	A	A	D	G	Q	M	V	P	F	S	A	F	S	S	S	R	W	E	Y	G	S	P	R	L	E	R	Y	N	G	L	P	S	M	E	I	L	G	Q	A	A	P	G	K	S	T	G	E	A	M	E	L	M	E	Q	L	A	S	K	L	P	T	G	V	G	Y	D	W	S	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)			T	T	S																		S						T	T												S	S	S		T													T	S		T	T
	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.	.	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910
Sequence	N	Q	A	P	S	L	Y	A	I	S	L	I	V	V	F	L	C	L	A	A	L	Y	E	S	W	S	I	P	F	S	V	M	L	V	V	P	L	G	V	I	G	A	L	L	A	A	T	F	R	G	L	T	N	D	V	Y	F	Q	V	G	L	L	T	T	I	G	L	S	A	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)	T																	T	T	S	S			S	S	S	G	G	G	T	G	G	G																S	S			B
	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.	.	.	.	.	970	.	.	.	.	.	.	.	.	.	980
Sequence	N	A	I	L	I	V	E	F	A	K	D	L	M	D	K	E	G	K	G	L	I	E	A	T	L	D	A	V	R	M	R	L	R	P	I	L	M	T	S	L	A	F	I	L	G	V	M	P	L	V	I	S	T	G	A	G	S	G	A	Q	N	A	V	G	T	G	V	M	G	G
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)														S	S	S				T	T	T							T	T	T															S					T	T			S	S		S
	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.
Sequence	M	V	T	A	T	V	L	A	I	F	F	V	P	V	F	F	V	V	V	R	R	R	F	S	R	K
Predicted secondary structure
SS confidence
Known secondary structure (DSSP)									T	S	S	S	S	S	S								T	T	T