Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	K	K	I	A	L	I	I	G	S	M	I	A	G	G	I	I	S	A	A	G	F	T	W	V	A	K	A	E	P	P	A	E	K	T	S	T	A	E	R	K	I	L	F	W	Y	D	P	M	Y	P	N	T	R	F	D	K	P	G	K
Secondary structure
SS confidence
Disorder		?	?	?	?	?																	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?														?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	P	F	M	D	M	D	L	V	P	K	Y	A	D	E	E	S	S	A	S	G	V	R	I	D	P	T	Q	T	Q	N	L	G	V	K	T	A	T	V	T	R	G	P	L	T	F	A	Q	S	F	P	A	N	V	S	Y	N	E	Y	Q
Secondary structure
SS confidence
Disorder		?	?											?	?	?	?	?	?	?	?	?				?					?	?			?					?		?	?	?	?	?															?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		Y	A	I	V	Q	A	R	A	A	G	F	I	D	K	V	Y	P	L	T	V	G	D	K	V	Q	K	G	T	P	L	L	D	L	T	I	P	D	W	V	E	A	Q	S	E	Y	L	L	L	R	E	T	G	G	T	A	T	Q	T	E	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		I	L	E	R	L	R	L	A	G	M	P	E	A	D	I	R	R	L	I	A	T	Q	K	I	Q	T	R	F	T	L	K	A	P	I	D	G	V	I	T	A	F	D	L	R	A	G	M	N	I	A	K	D	N	V	V	A	K	I	Q	G
Secondary structure
SS confidence
Disorder											?											?	?	?	?	?	?	?																		?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		M	D	P	V	W	V	T	A	A	I	P	E	S	I	A	W	L	V	K	D	A	S	Q	F	T	L	T	V	P	A	R	P	D	K	T	L	T	I	R	K	W	T	L	L	P	G	V	D	A	A	T	R	T	L	Q	L	R	L	E	V
Secondary structure
SS confidence
Disorder																		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		D	N	A	D	E	A	L	K	P	G	M	N	A	W	L	Q	L	N	T	A	S	E	P	M	L	L	I	P	S	Q	A	L	I	D	T	G	S	E	Q	R	V	I	T	V	D	A	D	G	R	F	V	P	K	R	V	A	V	F	Q	A
Secondary structure
SS confidence
Disorder																					?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.
Sequence		S	Q	G	V	T	A	L	R	S	G	L	A	E	G	E	K	V	V	S	S	G	L	F	L	I	D	S	E	A	N	I	S	G	A	L	E	R	M	R	S	E	S	A	T	H	A	H
Secondary structure
SS confidence
Disorder																										?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3h9i chain B Region: 90 - 385 Aligned: 295 Modelled: 295 Confidence: 100.0% Identity: 100% PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli Phyre2 PDB 2f1m chain A Region: 107 - 317 Aligned: 203 Modelled: 211 Confidence: 99.9% Identity: 19% PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra Phyre2 PDB 3lnn chain B Region: 103 - 320 Aligned: 216 Modelled: 218 Confidence: 99.9% Identity: 22% PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans Phyre2 PDB 3fpp chain B Region: 100 - 326 Aligned: 224 Modelled: 227 Confidence: 99.9% Identity: 18% PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca Phyre2 PDB 1t5e chain B Region: 109 - 317 Aligned: 203 Modelled: 209 Confidence: 99.9% Identity: 19% PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa Phyre2 PDB 1vf7 chain A Region: 105 - 320 Aligned: 210 Modelled: 216 Confidence: 99.9% Identity: 19% Fold: HlyD-like secretion proteins Superfamily: HlyD-like secretion proteins Family: HlyD-like secretion proteins Phyre2 PDB 2k33 chain A Region: 122 - 254 Aligned: 113 Modelled: 114 Confidence: 99.4% Identity: 17% PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation Phyre2 PDB 2b8g chain A Region: 123 - 243 Aligned: 72 Modelled: 73 Confidence: 98.5% Identity: 21% PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) Phyre2 PDB 1dcz chain A Region: 116 - 238 Aligned: 74 Modelled: 75 Confidence: 98.4% Identity: 23% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejg chain D Region: 123 - 238 Aligned: 67 Modelled: 68 Confidence: 98.4% Identity: 27% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 1o78 chain A Region: 116 - 238 Aligned: 74 Modelled: 75 Confidence: 98.2% Identity: 23% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejm chain A Region: 124 - 242 Aligned: 70 Modelled: 71 Confidence: 98.1% Identity: 33% PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase Phyre2 PDB 3n6r chain K Region: 117 - 238 Aligned: 73 Modelled: 74 Confidence: 98.0% Identity: 26% PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) Phyre2 PDB 2dn8 chain A Region: 117 - 238 Aligned: 72 Modelled: 74 Confidence: 98.0% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase Phyre2 PDB 2kcc chain A Region: 118 - 243 Aligned: 76 Modelled: 78 Confidence: 97.9% Identity: 21% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 Phyre2 PDB 1qjo chain A Region: 129 - 239 Aligned: 62 Modelled: 63 Confidence: 97.8% Identity: 26% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1ghj chain A Region: 129 - 240 Aligned: 63 Modelled: 64 Confidence: 97.8% Identity: 25% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1k8m chain A Region: 129 - 242 Aligned: 65 Modelled: 66 Confidence: 97.7% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1bdo chain A Region: 123 - 238 Aligned: 67 Modelled: 68 Confidence: 97.7% Identity: 25% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1iyu chain A Region: 129 - 242 Aligned: 65 Modelled: 66 Confidence: 97.7% Identity: 23% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1yuz chain B Region: 44 - 65 Aligned: 22 Modelled: 22 Confidence: 89.0% Identity: 18% PDB header:oxidoreductase Chain: B: PDB Molecule:nigerythrin; PDBTitle: partially reduced state of nigerythrin Phyre2 PDB 1dvb chain A Region: 44 - 65 Aligned: 22 Modelled: 22 Confidence: 85.0% Identity: 14% PDB header:electron transport Chain: A: PDB Molecule:rubrerythrin; PDBTitle: rubrerythrin Phyre2 PDB 1dgs chain A domain 1 Region: 58 - 69 Aligned: 12 Modelled: 12 Confidence: 53.1% Identity: 33% Fold: SAM domain-like Superfamily: RuvA domain 2-like Family: NAD+-dependent DNA ligase, domain 3 Phyre2 1 c3h9iB_ 2 c2f1mA_ 3 c3lnnB_ 4 c3fppB_ 5 c1t5eB_ 6 d1vf7a_ 7 c2k33A_ 8 c2b8gA_ 9 d1dcza_ 10 c2ejgD_ 11 d1o78a_ 12 c2ejmA_ 13 c3n6rK_ 14 c2dn8A_ 15 c2kccA_ 16 d1qjoa_ 17 d1ghja_ 18 d1k8ma_ 19 d1bdoa_ 20 d1iyua_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 c1yuzB_ 45 46 47 48 49 c1dvbA_ 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 d1dgsa1 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3h9iB_ 100.0 100 PDB header:transport protein Chain: B: PDB Molecule:cation efflux system protein cusb; PDBTitle: crystal structure of the membrane fusion protein cusb from escherichia2 coli 2 c2f1mA_ 99.9 19 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 3 c3lnnB_ 99.9 22 PDB header:metal transport Chain: B: PDB Molecule:membrane fusion protein (mfp) heavy metal cation efflux PDBTitle: crystal structure of zneb from cupriavidus metallidurans 4 c3fppB_ 99.9 18 PDB header:membrane protein Chain: B: PDB Molecule:macrolide-specific efflux protein maca; PDBTitle: crystal structure of e.coli maca 5 c1t5eB_ 99.9 19 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 6 d1vf7a_ 99.9 19 Fold:HlyD-like secretion proteins Superfamily:HlyD-like secretion proteins Family:HlyD-like secretion proteins 7 c2k33A_ 99.4 17 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 8 c2b8gA_ 98.5 21 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 9 d1dcza_ 98.4 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 10 c2ejgD_ 98.4 27 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 11 d1o78a_ 98.2 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 12 c2ejmA_ 98.1 33 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 13 c3n6rK_ 98.0 26 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 14 c2dn8A_ 98.0 21 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 15 c2kccA_ 97.9 21 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 16 d1qjoa_ 97.8 26 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 17 d1ghja_ 97.8 25 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 18 d1k8ma_ 97.7 17 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 19 d1bdoa_ 97.7 25 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 20 d1iyua_ 97.7 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 21 c2q8iB_ not modelled 97.7 21 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 22 d1y8ob1 not modelled 97.7 22 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 23 c2l5tA_ not modelled 97.5 23 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 24 c2dncA_ not modelled 97.5 32 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 25 d1laba_ not modelled 97.4 25 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 26 d1gjxa_ not modelled 97.3 28 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 27 c2dneA_ not modelled 97.0 17 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 28 d1pmra_ not modelled 96.8 15 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 29 c3fmcC_ not modelled 96.0 31 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 30 c2qj8B_ not modelled 95.0 23 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 31 c3na6A_ not modelled 94.3 21 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 32 d2pnrc1 not modelled 93.9 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 33 d2tpta3 not modelled 93.3 19 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 34 c2dsjA_ not modelled 92.3 21 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside (thymidine) phosphorylase; PDBTitle: crystal structure of project id tt0128 from thermus thermophilus hb8 35 c2qf7A_ not modelled 91.7 22 PDB header:ligase Chain: A: PDB Molecule:pyruvate carboxylase protein; PDBTitle: crystal structure of a complete multifunctional pyruvate carboxylase2 from rhizobium etli 36 d1uoua3 not modelled 91.5 22 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 37 c1otpA_ not modelled 91.4 19 PDB header:phosphorylase Chain: A: PDB Molecule:thymidine phosphorylase; PDBTitle: structural and theoretical studies suggest domain movement produces an2 active conformation of thymidine phosphorylase 38 d1brwa3 not modelled 91.4 33 Fold:alpha/beta-Hammerhead Superfamily:Pyrimidine nucleoside phosphorylase C-terminal domain Family:Pyrimidine nucleoside phosphorylase C-terminal domain 39 c3iftA_ not modelled 89.9 24 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from2 mycobacterium tuberculosis, using x-rays from the compact light3 source. 40 d1glaf_ not modelled 89.6 22 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 41 d2gpra_ not modelled 89.6 15 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 42 d2f3ga_ not modelled 89.2 22 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 43 c3mxuA_ not modelled 89.2 21 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae 44 c1yuzB_ 89.0 18 PDB header:oxidoreductase Chain: B: PDB Molecule:nigerythrin; PDBTitle: partially reduced state of nigerythrin 45 c1brwB_ not modelled 88.0 33 PDB header:transferase Chain: B: PDB Molecule:protein (pyrimidine nucleoside phosphorylase); PDBTitle: the crystal structure of pyrimidine nucleoside2 phosphorylase in a closed conformation 46 c3h5qA_ not modelled 87.7 33 PDB header:transferase Chain: A: PDB Molecule:pyrimidine-nucleoside phosphorylase; PDBTitle: crystal structure of a putative pyrimidine-nucleoside phosphorylase2 from staphylococcus aureus 47 c2j0fC_ not modelled 87.2 29 PDB header:transferase Chain: C: PDB Molecule:thymidine phosphorylase; PDBTitle: structural basis for non-competitive product inhibition in2 human thymidine phosphorylase: implication for drug design 48 d1gpra_ not modelled 86.5 22 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 49 c1dvbA_ 85.0 14 PDB header:electron transport Chain: A: PDB Molecule:rubrerythrin; PDBTitle: rubrerythrin 50 c2jkuA_ not modelled 84.5 21 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 51 c2hr5B_ not modelled 83.5 23 PDB header:metal binding protein Chain: B: PDB Molecule:rubrerythrin; PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form 52 c3cdxB_ not modelled 83.0 22 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 53 c2hsiB_ not modelled 82.1 22 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 54 c2gu1A_ not modelled 80.7 22 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 55 d1qwya_ not modelled 76.9 22 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 56 c2aukA_ not modelled 74.3 21 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 57 d1o4ua2 not modelled 67.7 10 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 58 c2b44A_ not modelled 67.7 22 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 59 c3d4rE_ not modelled 66.4 29 PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution 60 c2xhaB_ not modelled 65.9 28 PDB header:transcription Chain: B: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of domain 2 of thermotoga maritima n-utilization2 substance g (nusg) 61 d1yuja_ not modelled 65.2 18 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 62 d1e2wa2 not modelled 64.1 31 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 63 d1ci3m2 not modelled 64.1 25 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 64 d1onla_ not modelled 63.3 27 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 65 d1qpoa2 not modelled 62.8 21 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 66 c2edgA_ not modelled 62.5 23 PDB header:biosynthetic protein Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: solution structure of the gcv_h domain from mouse glycine 67 c3it5B_ not modelled 61.3 24 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 68 c1ctmA_ not modelled 60.7 16 PDB header:electron transport(cytochrome) Chain: A: PDB Molecule:cytochrome f; PDBTitle: crystal structure of chloroplast cytochrome f reveals a2 novel cytochrome fold and unexpected heme ligation 69 d1qapa2 not modelled 59.5 20 Fold:alpha/beta-Hammerhead Superfamily:Nicotinate/Quinolinate PRTase N-terminal domain-like Family:NadC N-terminal domain-like 70 d1yuza2 not modelled 59.0 18 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 71 c2xhcA_ not modelled 58.8 17 PDB header:transcription Chain: A: PDB Molecule:transcription antitermination protein nusg; PDBTitle: crystal structure of thermotoga maritima n-utilization substance g2 (nusg) 72 d1nnqa2 not modelled 56.5 19 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 73 d1hpca_ not modelled 55.9 23 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 74 c3a8jF_ not modelled 53.6 23 PDB header:transferase/transport protein Chain: F: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of et-ehred complex 75 d1dgsa1 53.1 33 Fold:SAM domain-like Superfamily:RuvA domain 2-like Family:NAD+-dependent DNA ligase, domain 3 76 d1ep3b1 not modelled 49.2 20 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 77 c3nyyA_ not modelled 48.6 31 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 78 c2aujD_ not modelled 48.5 44 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 79 d2cu8a1 not modelled 43.0 40 Fold:Glucocorticoid receptor-like (DNA-binding domain) Superfamily:Glucocorticoid receptor-like (DNA-binding domain) Family:LIM domain 80 d1lkoa2 not modelled 42.9 19 Fold:Rubredoxin-like Superfamily:Rubredoxin-like Family:Rubredoxin 81 c1e2vB_ not modelled 42.5 31 PDB header:electron transport proteins Chain: B: PDB Molecule:cytochrome f; PDBTitle: n153q mutant of cytochrome f from chlamydomonas reinhardtii 82 c2jxmB_ not modelled 41.4 38 PDB header:electron transport Chain: B: PDB Molecule:cytochrome f; PDBTitle: ensemble of twenty structures of the prochlorothrix2 hollandica plastocyanin- cytochrome f complex 83 c3iynM_ not modelled 41.0 22 PDB header:virus Chain: M: PDB Molecule:penton base protein; PDBTitle: 3.6-angstrom cryoem structure of human adenovirus type 5 84 d2i4sa1 not modelled 40.7 12 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 85 c2bldD_ not modelled 40.6 22 PDB header:virus Chain: D: PDB Molecule:penton protein; PDBTitle: the quasi-atomic model of human adenovirus type 52 capsid (part 1) 86 c2zpmA_ not modelled 40.5 16 PDB header:hydrolase Chain: A: PDB Molecule:regulator of sigma e protease; PDBTitle: crystal structure analysis of pdz domain b 87 d1krha1 not modelled 40.5 17 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 88 c3csqC_ not modelled 39.8 33 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 89 c2owoA_ not modelled 38.9 25 PDB header:ligase/dna Chain: A: PDB Molecule:dna ligase; PDBTitle: last stop on the road to repair: structure of e.coli dna ligase bound2 to nicked dna-adenylate 90 d2j01q1 not modelled 38.5 10 Fold:alpha/beta-Hammerhead Superfamily:Ribosomal protein L16p/L10e Family:Ribosomal protein L16p 91 c2kjpA_ not modelled 38.0 12 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein ylbl; PDBTitle: solution structure of protein ylbl (bsu15050) from bacillus2 subtilis, northeast structural genomics consortium target3 sr713a 92 c3ndjA_ not modelled 37.8 7 PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: x-ray structure of a c-3'-methyltransferase in complex with s-2 adenosyl-l-homocysteine and sugar product 93 c1v9pB_ not modelled 37.4 33 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase 94 c1q90A_ not modelled 36.7 31 PDB header:photosynthesis Chain: A: PDB Molecule:apocytochrome f; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 95 c1tu2B_ not modelled 36.7 25 PDB header:electron transport Chain: B: PDB Molecule:apocytochrome f; PDBTitle: the complex of nostoc cytochrome f and plastocyanin determin with2 paramagnetic nmr. based on the structures of cytochrome f and3 plastocyanin, 10 structures 96 d1pvma3 not modelled 36.2 24 Fold:Rubredoxin-like Superfamily:Hypothetical protein Ta0289 C-terminal domain Family:Hypothetical protein Ta0289 C-terminal domain 97 c1dgsB_ not modelled 35.0 33 PDB header:ligase Chain: B: PDB Molecule:dna ligase; PDBTitle: crystal structure of nad+-dependent dna ligase from t.2 filiformis 98 d2i6va1 not modelled 33.8 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:EpsC C-terminal domain-like 99 d2gmga1 not modelled 33.1 25 Fold:DNA/RNA-binding 3-helical bundle Superfamily:"Winged helix" DNA-binding domain Family:PF0610-like 100 c2e75C_ not modelled 32.8 25 PDB header:photosynthesis Chain: C: PDB Molecule:apocytochrome f; PDBTitle: crystal structure of the cytochrome b6f complex with 2-nonyl-4-2 hydroxyquinoline n-oxide (nqno) from m.laminosus 101 c2ftcI_ not modelled 31.6 15 PDB header:ribosome Chain: I: PDB Molecule:mitochondrial ribosomal protein l16; PDBTitle: structural model for the large subunit of the mammalian mitochondrial2 ribosome 102 d1qfja1 not modelled 29.9 15 Fold:Reductase/isomerase/elongation factor common domain Superfamily:Riboflavin synthase domain-like Family:Ferredoxin reductase FAD-binding domain-like 103 d1hf2a1 not modelled 29.7 13 Fold:Single-stranded right-handed beta-helix Superfamily:Cell-division inhibitor MinC, C-terminal domain Family:Cell-division inhibitor MinC, C-terminal domain 104 d1tu2b2 not modelled 29.4 25 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 105 c3bboO_ not modelled 29.2 14 PDB header:ribosome Chain: O: PDB Molecule:ribosomal protein l16; PDBTitle: homology model for the spinach chloroplast 50s subunit2 fitted to 9.4a cryo-em map of the 70s chlororibosome 106 d1sota1 not modelled 29.1 15 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 107 c2kl1A_ not modelled 26.9 12 PDB header:protein binding Chain: A: PDB Molecule:ylbl protein; PDBTitle: solution structure of gtr34c from geobacillus thermodenitrificans.2 northeast structural genomics consortium target gtr34c 108 c2k5cA_ not modelled 26.4 33 PDB header:metal binding protein Chain: A: PDB Molecule:uncharacterized protein pf0385; PDBTitle: nmr structure for pf0385 109 d1akya2 not modelled 25.5 20 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 110 d2ak3a2 not modelled 25.3 23 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 111 c3i18A_ not modelled 25.0 9 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:lmo2051 protein; PDBTitle: crystal structure of the pdz domain of the sdrc-like protein2 (lmo2051) from listeria monocytogenes, northeast structural3 genomics consortium target lmr166b 112 d1hcza2 not modelled 24.7 19 Fold:Barrel-sandwich hybrid Superfamily:Rudiment single hybrid motif Family:Cytochrome f, small domain 113 d1jj2h_ not modelled 24.5 4 Fold:alpha/beta-Hammerhead Superfamily:Ribosomal protein L16p/L10e Family:Ribosomal protein L10e 114 d1e4va2 not modelled 24.4 23 Fold:Rubredoxin-like Superfamily:Microbial and mitochondrial ADK, insert "zinc finger" domain Family:Microbial and mitochondrial ADK, insert "zinc finger" domain 115 d1ky9a1 not modelled 24.4 20 Fold:PDZ domain-like Superfamily:PDZ domain-like Family:HtrA-like serine proteases 116 d1j1la_ not modelled 23.7 17 Fold:Double-stranded beta-helix Superfamily:RmlC-like cupins Family:Pirin-like 117 c1w8xP_ not modelled 22.9 19 PDB header:virus Chain: P: PDB Molecule:protein p16; PDBTitle: structural analysis of prd1 118 d2epqa1 not modelled 22.7 30 Fold:beta-beta-alpha zinc fingers Superfamily:beta-beta-alpha zinc fingers Family:Classic zinc finger, C2H2 119 d1ffkf_ not modelled 21.4 0 Fold:alpha/beta-Hammerhead Superfamily:Ribosomal protein L16p/L10e Family:Ribosomal protein L10e 120 d1uwfa1 not modelled 21.1 18 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:Bacterial adhesins Family:Pilus subunits

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0