Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	L	N	S	F	K	L	S	L	Q	Y	I	L	P	K	L	W	L	T	R	L	A	G	W	G	A	S	K	R	A	G	W	L	T	K	L	V	I	D	L	F	V	K	Y	Y	K	V	D	M	K	E	A	Q	K	P	D	T	A	S	Y
Secondary structure
SS confidence
Disorder		?	?	?	?									?															?	?	?		?	?																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	T	F	N	E	F	F	V	R	P	L	R	D	E	V	R	P	I	D	T	D	P	N	V	L	V	M	P	A	D	G	V	I	S	Q	L	G	K	I	E	E	D	K	I	L	Q	A	K	G	H	N	Y	S	L	E	A	L	L	A	G
Secondary structure
SS confidence
Disorder																																																												?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		N	Y	L	M	A	D	L	F	R	N	G	T	F	V	T	T	Y	L	S	P	R	D	Y	H	R	V	H	M	P	C	N	G	I	L	R	E	M	I	Y	V	P	G	D	L	F	S	V	N	H	L	T	A	Q	N	V	P	N	L	F	A
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		R	N	E	R	V	I	C	L	F	D	T	E	F	G	P	M	A	Q	I	L	V	G	A	T	I	V	G	S	I	E	T	V	W	A	G	T	I	T	P	P	R	E	G	I	I	K	R	W	T	W	P	A	G	E	N	D	G	S	V	A
Secondary structure
SS confidence
Disorder																																																								?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		L	L	K	G	Q	E	M	G	R	F	K	L	G	S	T	V	I	N	L	F	A	P	G	K	V	N	L	V	E	Q	L	E	S	L	S	V	T	K	I	G	Q	P	L	A	V	S	T	E	T	F	V	T	P	D	A	E	P	A	P	L
Secondary structure
SS confidence
Disorder					?																																							?		?		?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.
Sequence		P	A	E	E	I	E	A	E	H	D	A	S	P	L	V	D	D	K	K	D	Q	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2gpr chain A Region: 84 - 286 Aligned: 138 Modelled: 142 Confidence: 97.4% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 1gpr chain A Region: 81 - 282 Aligned: 137 Modelled: 141 Confidence: 96.7% Identity: 17% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2f3g chain A Region: 84 - 289 Aligned: 141 Modelled: 145 Confidence: 96.6% Identity: 16% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 1gla chain F Region: 80 - 289 Aligned: 144 Modelled: 149 Confidence: 96.4% Identity: 13% Fold: Barrel-sandwich hybrid Superfamily: Duplicated hybrid motif Family: Glucose permease-like Phyre2 PDB 2dnc chain A Region: 202 - 302 Aligned: 96 Modelled: 101 Confidence: 89.6% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase Phyre2 PDB 2ejm chain A Region: 233 - 303 Aligned: 70 Modelled: 71 Confidence: 88.8% Identity: 9% PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase Phyre2 PDB 2dn8 chain A Region: 213 - 302 Aligned: 88 Modelled: 90 Confidence: 88.7% Identity: 9% PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase Phyre2 PDB 1bdo chain A Region: 200 - 286 Aligned: 73 Modelled: 73 Confidence: 88.4% Identity: 12% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2b8g chain A Region: 201 - 291 Aligned: 70 Modelled: 70 Confidence: 88.2% Identity: 13% PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) Phyre2 PDB 1lab chain A Region: 233 - 288 Aligned: 56 Modelled: 56 Confidence: 87.1% Identity: 11% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2ejg chain D Region: 220 - 286 Aligned: 67 Modelled: 67 Confidence: 87.0% Identity: 10% PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 Phyre2 PDB 1y8o chain B domain 1 Region: 232 - 303 Aligned: 72 Modelled: 72 Confidence: 85.9% Identity: 13% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1dcz chain A Region: 200 - 286 Aligned: 66 Modelled: 66 Confidence: 85.9% Identity: 11% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1ghj chain A Region: 231 - 289 Aligned: 59 Modelled: 59 Confidence: 85.1% Identity: 12% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 2dne chain A Region: 202 - 311 Aligned: 105 Modelled: 110 Confidence: 84.6% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase Phyre2 PDB 2qik chain A Region: 159 - 254 Aligned: 75 Modelled: 96 Confidence: 83.5% Identity: 19% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0131 protein ykqa; PDBTitle: crystal structure of ykqa from bacillus subtilis. northeast2 structural genomics target sr631 Phyre2 PDB 2l5t chain A Region: 232 - 286 Aligned: 55 Modelled: 55 Confidence: 81.8% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum Phyre2 PDB 1qjo chain A Region: 233 - 290 Aligned: 58 Modelled: 58 Confidence: 81.7% Identity: 7% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1iyu chain A Region: 232 - 290 Aligned: 59 Modelled: 59 Confidence: 81.5% Identity: 7% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 PDB 1gjx chain A Region: 233 - 286 Aligned: 54 Modelled: 54 Confidence: 81.3% Identity: 9% Fold: Barrel-sandwich hybrid Superfamily: Single hybrid motif Family: Biotinyl/lipoyl-carrier proteins and domains Phyre2 1 d2gpra_ 2 d1gpra_ 3 d2f3ga_ 4 d1glaf_ 5 c2dncA_ 6 c2ejmA_ 7 c2dn8A_ 8 d1bdoa_ 9 c2b8gA_ 10 d1laba_ 11 c2ejgD_ 12 d1y8ob1 13 d1dcza_ 14 d1ghja_ 15 c2dneA_ 16 c2qikA_ 17 c2l5tA_ 18 d1qjoa_ 19 d1iyua_ 20 d1gjxa_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2gpra_ 97.4 17 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 2 d1gpra_ 96.7 17 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 3 d2f3ga_ 96.6 16 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 4 d1glaf_ 96.4 13 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Glucose permease-like 5 c2dncA_ 89.6 16 PDB header:transferase Chain: A: PDB Molecule:pyruvate dehydrogenase protein x component; PDBTitle: solution structure of rsgi ruh-054, a lipoyl domain from2 human 2-oxoacid dehydrogenase 6 c2ejmA_ 88.8 9 PDB header:ligase Chain: A: PDB Molecule:methylcrotonoyl-coa carboxylase subunit alpha; PDBTitle: solution structure of ruh-072, an apo-biotnyl domain form2 human acetyl coenzyme a carboxylase 7 c2dn8A_ 88.7 9 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of rsgi ruh-053, an apo-biotin carboxy2 carrier protein from human transcarboxylase 8 d1bdoa_ 88.4 12 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 9 c2b8gA_ 88.2 13 PDB header:biosynthetic protein Chain: A: PDB Molecule:biotin/lipoyl attachment protein; PDBTitle: solution structure of bacillus subtilis blap biotinylated-2 form (energy minimized mean structure) 10 d1laba_ 87.1 11 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 11 c2ejgD_ 87.0 10 PDB header:ligase Chain: D: PDB Molecule:149aa long hypothetical methylmalonyl-coa decarboxylase PDBTitle: crystal structure of the biotin protein ligase (mutation r48a) and2 biotin carboxyl carrier protein complex from pyrococcus horikoshii3 ot3 12 d1y8ob1 85.9 13 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 13 d1dcza_ 85.9 11 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 14 d1ghja_ 85.1 12 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 15 c2dneA_ 84.6 12 PDB header:transferase Chain: A: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase PDBTitle: solution structure of rsgi ruh-058, a lipoyl domain of2 human 2-oxoacid dehydrogenase 16 c2qikA_ 83.5 19 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:upf0131 protein ykqa; PDBTitle: crystal structure of ykqa from bacillus subtilis. northeast2 structural genomics target sr631 17 c2l5tA_ 81.8 13 PDB header:transferase Chain: A: PDB Molecule:lipoamide acyltransferase; PDBTitle: solution nmr structure of e2 lipoyl domain from thermoplasma2 acidophilum 18 d1qjoa_ 81.7 7 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 19 d1iyua_ 81.5 7 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 20 d1gjxa_ 81.3 9 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 21 c2kccA_ not modelled 78.9 8 PDB header:ligase Chain: A: PDB Molecule:acetyl-coa carboxylase 2; PDBTitle: solution structure of biotinoyl domain from human acetyl-2 coa carboxylase 2 22 d1k8ma_ not modelled 77.8 10 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 23 c2q8iB_ not modelled 75.7 14 PDB header:transferase Chain: B: PDB Molecule:dihydrolipoyllysine-residue acetyltransferase component of PDBTitle: pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug2 radicicol 24 d1pmra_ not modelled 75.4 7 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 25 d1o78a_ not modelled 73.1 9 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 26 c1urzC_ not modelled 59.5 34 PDB header:virus/viral protein Chain: C: PDB Molecule:envelope protein; PDBTitle: low ph induced, membrane fusion conformation of the2 envelope protein of tick-borne encephalitis virus 27 c3cdxB_ not modelled 50.4 13 PDB header:hydrolase Chain: B: PDB Molecule:succinylglutamatedesuccinylase/aspartoacylase; PDBTitle: crystal structure of2 succinylglutamatedesuccinylase/aspartoacylase from3 rhodobacter sphaeroides 28 d1z66a1 not modelled 45.9 22 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 29 c2jqmA_ not modelled 40.9 31 PDB header:transferase Chain: A: PDB Molecule:envelope protein e; PDBTitle: yellow fever envelope protein domain iii nmr structure2 (s288-k398) 30 c3na6A_ not modelled 39.7 19 PDB header:hydrolase Chain: A: PDB Molecule:succinylglutamate desuccinylase/aspartoacylase; PDBTitle: crystal structure of a succinylglutamate desuccinylase (tm1040_2694)2 from silicibacter sp. tm1040 at 2.00 a resolution 31 c1vdzA_ not modelled 39.5 17 PDB header:hydrolase Chain: A: PDB Molecule:a-type atpase subunit a; PDBTitle: crystal structure of a-type atpase catalytic subunit a from2 pyrococcus horikoshii ot3 32 c2hsiB_ not modelled 38.5 18 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative peptidase m23; PDBTitle: crystal structure of putative peptidase m23 from2 pseudomonas aeruginosa, new york structural genomics3 consortium 33 c2h0pA_ not modelled 38.4 28 PDB header:viral protein Chain: A: PDB Molecule:envelope glycoprotein; PDBTitle: nmr structure of the dengue-4 virus envelope protein domain2 iii 34 c2qj8B_ not modelled 37.5 11 PDB header:hydrolase Chain: B: PDB Molecule:mlr6093 protein; PDBTitle: crystal structure of an aspartoacylase family protein (mlr6093) from2 mesorhizobium loti maff303099 at 2.00 a resolution 35 d1svba1 not modelled 36.9 22 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 36 d1pjwa_ not modelled 30.2 31 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 37 d1xpma2 not modelled 30.2 40 Fold:Thiolase-like Superfamily:Thiolase-like Family:Chalcone synthase-like 38 c2ka7A_ not modelled 29.7 30 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: nmr solution structure of tm0212 at 40 c 39 d1qwya_ not modelled 29.6 20 Fold:Barrel-sandwich hybrid Superfamily:Duplicated hybrid motif Family:Peptidoglycan hydrolase LytM 40 c3mxuA_ not modelled 29.5 20 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from bartonella2 henselae 41 c3lazB_ not modelled 28.5 5 PDB header:lyase Chain: B: PDB Molecule:d-galactarate dehydratase; PDBTitle: the crystal structure of the n-terminal domain of d-2 galactarate dehydratase from escherichia coli cft073 42 c2aujD_ not modelled 28.4 15 PDB header:transferase Chain: D: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of thermus aquaticus rna polymerase beta'-subunit2 insert 43 c1otcB_ not modelled 26.9 35 PDB header:protein/dna Chain: B: PDB Molecule:protein (telomere-binding protein beta subunit); PDBTitle: the o. nova telomere end binding protein complexed with2 single strand dna 44 c2i0qB_ not modelled 26.5 35 PDB header:structural protein/dna Chain: B: PDB Molecule:telomere-binding protein beta subunit; PDBTitle: crystal structure of a telomere single-strand dna-protein2 complex from o. nova with full-length alpha and beta3 telomere proteins 45 d1jb7b_ not modelled 26.5 35 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 46 d1ok8a1 not modelled 26.0 25 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 47 c3egpA_ not modelled 25.3 25 PDB header:viral protein Chain: A: PDB Molecule:envelope protein; PDBTitle: crystal structure analysis of dengue-1 envelope protein2 domain iii 48 c2jkuA_ not modelled 24.7 13 PDB header:ligase Chain: A: PDB Molecule:propionyl-coa carboxylase alpha chain, PDBTitle: crystal structure of the n-terminal region of the biotin2 acceptor domain of human propionyl-coa carboxylase 49 c2aukA_ not modelled 24.0 23 PDB header:transferase Chain: A: PDB Molecule:dna-directed rna polymerase beta' chain; PDBTitle: structure of e. coli rna polymerase beta' g/g' insert 50 c2b44A_ not modelled 23.8 20 PDB header:hydrolase Chain: A: PDB Molecule:glycyl-glycine endopeptidase lytm; PDBTitle: truncated s. aureus lytm, p 32 2 1 crystal form 51 c3it5B_ not modelled 22.4 18 PDB header:hydrolase Chain: B: PDB Molecule:protease lasa; PDBTitle: crystal structure of the lasa virulence factor from pseudomonas2 aeruginosa 52 c3iftA_ not modelled 21.2 18 PDB header:oxidoreductase Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: crystal structure of glycine cleavage system protein h from2 mycobacterium tuberculosis, using x-rays from the compact light3 source. 53 c2edgA_ not modelled 20.7 18 PDB header:biosynthetic protein Chain: A: PDB Molecule:glycine cleavage system h protein; PDBTitle: solution structure of the gcv_h domain from mouse glycine 54 c2r9qD_ not modelled 19.9 22 PDB header:hydrolase Chain: D: PDB Molecule:2'-deoxycytidine 5'-triphosphate deaminase; PDBTitle: crystal structure of 2'-deoxycytidine 5'-triphosphate deaminase from2 agrobacterium tumefaciens 55 d1wqla2 not modelled 19.5 24 Fold:TBP-like Superfamily:Bet v1-like Family:Ring hydroxylating alpha subunit catalytic domain 56 d1r0va2 not modelled 19.3 11 Fold:Restriction endonuclease-like Superfamily:tRNA-intron endonuclease catalytic domain-like Family:tRNA-intron endonuclease catalytic domain-like 57 c2k33A_ not modelled 19.0 24 PDB header:membrane protein, transport protein Chain: A: PDB Molecule:acra; PDBTitle: solution structure of an n-glycosylated protein using in2 vitro glycosylation 58 d2b1xa2 not modelled 18.2 21 Fold:TBP-like Superfamily:Bet v1-like Family:Ring hydroxylating alpha subunit catalytic domain 59 d1onla_ not modelled 18.0 34 Fold:Barrel-sandwich hybrid Superfamily:Single hybrid motif Family:Biotinyl/lipoyl-carrier proteins and domains 60 c2gu1A_ not modelled 16.4 16 PDB header:hydrolase Chain: A: PDB Molecule:zinc peptidase; PDBTitle: crystal structure of a zinc containing peptidase from2 vibrio cholerae 61 c3fmcC_ not modelled 15.9 18 PDB header:hydrolase Chain: C: PDB Molecule:putative succinylglutamate desuccinylase / aspartoacylase; PDBTitle: crystal structure of a putative succinylglutamate desuccinylase /2 aspartoacylase family protein (sama_0604) from shewanella amazonensis3 sb2b at 1.80 a resolution 62 d2q07a1 not modelled 15.6 21 Fold:PUA domain-like Superfamily:PUA domain-like Family:PUA domain 63 d1ulia2 not modelled 14.8 24 Fold:TBP-like Superfamily:Bet v1-like Family:Ring hydroxylating alpha subunit catalytic domain 64 d2bmoa2 not modelled 14.7 16 Fold:TBP-like Superfamily:Bet v1-like Family:Ring hydroxylating alpha subunit catalytic domain 65 d1o7na2 not modelled 14.5 16 Fold:TBP-like Superfamily:Bet v1-like Family:Ring hydroxylating alpha subunit catalytic domain 66 c3c6dB_ not modelled 13.7 31 PDB header:virus Chain: B: PDB Molecule:polyprotein; PDBTitle: the pseudo-atomic structure of dengue immature virus 67 d2f5tx2 not modelled 13.6 21 Fold:Phospholipase D/nuclease Superfamily:Phospholipase D/nuclease Family:TrmB middle domain-like 68 c3lehA_ not modelled 13.5 35 PDB header:transferase Chain: A: PDB Molecule:putative hydroxymethylglutaryl-coa synthase; PDBTitle: the crystal structure of smu.943c from streptococcus mutans ua159 69 c2f9aA_ not modelled 12.9 33 PDB header:transferase Chain: A: PDB Molecule:3-hydroxy-3-methylglutaryl coenzyme a synthase 1; PDBTitle: hmg-coa synthase from brassica juncea in complex with f-244 70 d1miua3 not modelled 12.5 24 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 71 c2lc0A_ not modelled 12.4 15 PDB header:protein binding Chain: A: PDB Molecule:putative uncharacterized protein tb39.8; PDBTitle: rv0020c_nter structure 72 d1s6na_ not modelled 12.3 32 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 73 c3k3sG_ not modelled 12.3 15 PDB header:hydrolase Chain: G: PDB Molecule:altronate hydrolase; PDBTitle: crystal structure of altronate hydrolase (fragment 1-84) from shigella2 flexneri. 74 c3csqC_ not modelled 12.3 40 PDB header:hydrolase Chain: C: PDB Molecule:morphogenesis protein 1; PDBTitle: crystal and cryoem structural studies of a cell wall2 degrading enzyme in the bacteriophage phi29 tail 75 c3uajA_ not modelled 12.2 21 PDB header:viral protein/immune system Chain: A: PDB Molecule:envelope protein; PDBTitle: crystal structure of the envelope glycoprotein ectodomain from dengue2 virus serotype 4 in complex with the fab fragment of the chimpanzee3 monoclonal antibody 5h2 76 c3c64A_ not modelled 12.0 25 PDB header:cd36-binding protein,cell adhesion Chain: A: PDB Molecule:pfemp1 variant 2 of strain mc; PDBTitle: the mc179 portion of the cysteine-rich interdomain region2 (cidr) of a plasmodium falciparum erythrocyte membrane3 protein-1 (pfemp1) 77 c2f1mA_ not modelled 11.9 15 PDB header:transport protein Chain: A: PDB Molecule:acriflavine resistance protein a; PDBTitle: conformational flexibility in the multidrug efflux system protein acra 78 c1x9eB_ not modelled 11.5 35 PDB header:lyase Chain: B: PDB Molecule:hmg-coa synthase; PDBTitle: crystal structure of hmg-coa synthase from enterococcus2 faecalis 79 d2nqwa1 not modelled 11.5 11 Fold:FAD-binding/transporter-associated domain-like Superfamily:FAD-binding/transporter-associated domain-like Family:CorC/HlyC domain-like 80 c1txtB_ not modelled 11.5 40 PDB header:lyase Chain: B: PDB Molecule:3-hydroxy-3-methylglutaryl-coa synthase; PDBTitle: staphylococcus aureus 3-hydroxy-3-methylglutaryl-coa2 synthase 81 c2wusR_ not modelled 11.3 18 PDB header:structural protein Chain: R: PDB Molecule:putative uncharacterized protein; PDBTitle: bacterial actin mreb assembles in complex with cell shape2 protein rodz 82 c3nyyA_ not modelled 10.9 18 PDB header:hydrolase Chain: A: PDB Molecule:putative glycyl-glycine endopeptidase lytm; PDBTitle: crystal structure of a putative glycyl-glycine endopeptidase lytm2 (rumgna_02482) from ruminococcus gnavus atcc 29149 at 1.60 a3 resolution 83 c2f5tX_ not modelled 10.5 21 PDB header:transcription Chain: X: PDB Molecule:archaeal transcriptional regulator trmb; PDBTitle: crystal structure of the sugar binding domain of the archaeal2 transcriptional regulator trmb 84 d1ztxe1 not modelled 10.5 27 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Class II viral fusion proteins C-terminal domain 85 c2p8uB_ not modelled 10.0 43 PDB header:transferase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa synthase, cytoplasmic; PDBTitle: crystal structure of human 3-hydroxy-3-methylglutaryl coa synthase i 86 c3d4rE_ not modelled 9.9 18 PDB header:unknown function Chain: E: PDB Molecule:domain of unknown function from the pfam-b_34464 family; PDBTitle: crystal structure of a duf2118 family protein (mmp0046) from2 methanococcus maripaludis at 2.20 a resolution 87 c1orhA_ not modelled 9.5 14 PDB header:transferase Chain: A: PDB Molecule:protein arginine n-methyltransferase 1; PDBTitle: structure of the predominant protein arginine methyltransferase prmt1 88 c3e9uA_ not modelled 9.1 24 PDB header:membrane protein Chain: A: PDB Molecule:na/ca exchange protein; PDBTitle: crystal structure of calx cbd2 domain 89 d2gtaa1 not modelled 9.0 13 Fold:all-alpha NTP pyrophosphatases Superfamily:all-alpha NTP pyrophosphatases Family:MazG-like 90 c3ddcB_ not modelled 8.9 11 PDB header:hydrolase/apoptosis Chain: B: PDB Molecule:ras association domain-containing family protein 5; PDBTitle: crystal structure of nore1a in complex with ras 91 c3n6rK_ not modelled 8.8 16 PDB header:ligase Chain: K: PDB Molecule:propionyl-coa carboxylase, alpha subunit; PDBTitle: crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) 92 d1iyjb3 not modelled 8.6 24 Fold:OB-fold Superfamily:Nucleic acid-binding proteins Family:Single strand DNA-binding domain, SSB 93 c3fymA_ not modelled 8.3 5 PDB header:dna binding protein Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: the 1a structure of ymfm, a putative dna-binding membrane2 protein from staphylococcus aureus 94 c3llbA_ not modelled 8.2 8 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: the crystal structure of the protein pa3983 with unknown2 function from pseudomonas aeruginosa pao1 95 c1t5eB_ not modelled 8.1 21 PDB header:transport protein Chain: B: PDB Molecule:multidrug resistance protein mexa; PDBTitle: the structure of mexa 96 d1y7ma2 not modelled 7.7 13 Fold:LysM domain Superfamily:LysM domain Family:LysM domain 97 d3brda3 not modelled 7.6 13 Fold:beta-Trefoil Superfamily:DNA-binding protein LAG-1 (CSL) Family:DNA-binding protein LAG-1 (CSL) 98 d2a9da1 not modelled 7.4 28 Fold:Immunoglobulin-like beta-sandwich Superfamily:E set domains Family:Molybdenum-containing oxidoreductases-like dimerisation domain 99 d2fx0a2 not modelled 7.4 33 Fold:Tetracyclin repressor-like, C-terminal domain Superfamily:Tetracyclin repressor-like, C-terminal domain Family:Tetracyclin repressor-like, C-terminal domain

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0