Phyre 2 Results for P76072

Email	l.a.kelley@imperial.ac.uk
Description	P76072
Date	Thu Jan 5 12:18:11 GMT 2012
Unique Job ID	6315adbda0ecea32

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c2xgfA_

Top template information

PDB header:viral protein
Chain: A: PDB Molecule:long tail fiber protein p37;
PDBTitle: structure of the bacteriophage t4 long tail fibre needle-2 shaped receptor-binding tip

Confidence and coverage

Confidence:

98.6%

Coverage:

19%

216 residues ( 19% of your sequence) have been modelled with 98.6% confidence by the single highest scoring template.

Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.

315 residues ( 28%) could be modelled at >90% confidence using multiple-templates.

You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.

Warning: 61% of your sequence is predicted disordered. Disordered regions cannot be meaningfully predicted.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M A V K I S G V L K D G T G K P V Q N C T I Q L K A K R N S T T V V V N T L A S E N P D E A G R Y S M D V E Y G Q Y S V

Secondary structure

SS confidence

Disorder ? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 70 . . . . . . . . . 80 . . . . . . . . . 90 . . . . . . . . . 100 . . . . . . . . . 110 . . . . . . . . . 120

Sequence I L L V E G F P P S H A G T I T V Y E D S Q P G T L N D F L G A M T E D D A R P E A L R R F E L M V E E V A R N A S A V

Secondary structure

SS confidence

Disorder
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 130 . . . . . . . . . 140 . . . . . . . . . 150 . . . . . . . . . 160 . . . . . . . . . 170 . . . . . . . . . 180

Sequence A Q N T A A A K K S A S D A S T S A R E A A T H A A D A A D S A R A A S T S A G Q A A S S A Q S A S S S A G T A S T K A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 190 . . . . . . . . . 200 . . . . . . . . . 210 . . . . . . . . . 220 . . . . . . . . . 230 . . . . . . . . . 240

Sequence T E A S K S A A A A E S S K S A A A T S A G A A K T S E T N A S A S L Q S A A T S A S T A T T K A S E A A T S A R D A A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 250 . . . . . . . . . 260 . . . . . . . . . 270 . . . . . . . . . 280 . . . . . . . . . 290 . . . . . . . . . 300

Sequence A S K E A A K S S E T N A S S S A S S A A S S A T A A G N S A K A A K T S E T N A R S S E T A A G Q S A S A A A G S K T

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 310 . . . . . . . . . 320 . . . . . . . . . 330 . . . . . . . . . 340 . . . . . . . . . 350 . . . . . . . . . 360

Sequence A A A S S A S A A S T S A G Q A S A S A T A A G K S A E S A A S S A S T A T T K A G E A T E Q A S A A A R S A S A A K T

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 370 . . . . . . . . . 380 . . . . . . . . . 390 . . . . . . . . . 400 . . . . . . . . . 410 . . . . . . . . . 420

Sequence S E T N A K A S E T S A E S S K T A A A S S A S S A A S S A S S A S A S K D E A T R Q A S A A K S S A T T A S T K A T E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 430 . . . . . . . . . 440 . . . . . . . . . 450 . . . . . . . . . 460 . . . . . . . . . 470 . . . . . . . . . 480

Sequence A A G S A T A A A Q S K S T A E S A A T R A E T A A K R A E D I A S A V A L E D A S T T K K G I V Q L S S A T N S T S E

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 490 . . . . . . . . . 500 . . . . . . . . . 510 . . . . . . . . . 520 . . . . . . . . . 530 . . . . . . . . . 540

Sequence T L A A T P K A V K S A Y D N A E K R L Q K D Q N G A D I P D K G C F L N N I N A V S K T D F A D K R G M R Y V R V N A

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 550 . . . . . . . . . 560 . . . . . . . . . 570 . . . . . . . . . 580 . . . . . . . . . 590 . . . . . . . . . 600

Sequence P A G A T S G K Y Y P V V V M R S A G S V S E L A S R V I I T T A T R T A G D P M N N C E F N G F V M P G G W T D R G R

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ?
? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 610 . . . . . . . . . 620 . . . . . . . . . 630 . . . . . . . . . 640 . . . . . . . . . 650 . . . . . . . . . 660

Sequence Y A Y G M F W Q Y Q N N E R A I H S I M M S N K G D D L R S V F Y V D G A A F P V F A F I E D G L S I S A P G A D L V V

Secondary structure

SS confidence

Disorder
? ?
? ? ? ?
?
?
?
? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 670 . . . . . . . . . 680 . . . . . . . . . 690 . . . . . . . . . 700 . . . . . . . . . 710 . . . . . . . . . 720

Sequence N D T T Y K F G A T N P A T E C I A A D V I L D F K S G R G F Y E S H S L I V N D N L S C K K L F A T D E I V A R G G N

Secondary structure

SS confidence

Disorder ?
? ?
? ? ? ? ? ? ? ?
? ? ? ?

Disorder confidence

. . . . . . . . . 730 . . . . . . . . . 740 . . . . . . . . . 750 . . . . . . . . . 760 . . . . . . . . . 770 . . . . . . . . . 780

Sequence Q I R M I G G E Y G A L W R N D G A K T Y L L L T N Q G D V Y G G W N T L R P F A I D N A T G E L V I G T K L S A S L N

Secondary structure

SS confidence

Disorder
? ? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 790 . . . . . . . . . 800 . . . . . . . . . 810 . . . . . . . . . 820 . . . . . . . . . 830 . . . . . . . . . 840

Sequence G N A L T A T K L Q T P R R V S G V E F D G S K D I T L T A A H V A A F A R R A T D T Y A D A D G G V P W N A E S G A Y

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ?
? ?

Disorder confidence

. . . . . . . . . 850 . . . . . . . . . 860 . . . . . . . . . 870 . . . . . . . . . 880 . . . . . . . . . 890 . . . . . . . . . 900

Sequence N V T R S G D S Y I L V N F Y T G V G S C R T L Q M K A H Y R N G G L F Y R S S R D G Y G F E E D W A E V Y T S K N L P

Secondary structure

SS confidence

Disorder
?
?
? ? ? ? ?
?
? ?

Disorder confidence

. . . . . . . . . 910 . . . . . . . . . 920 . . . . . . . . . 930 . . . . . . . . . 940 . . . . . . . . . 950 . . . . . . . . . 960

Sequence P E S Y P V G A P I P W P S D T V P S G Y A L M Q G Q A F D K S A Y P K L A A A Y P S G V I P D M R G W T I K G K P A S

Secondary structure

SS confidence

Disorder ? ? ?
?

Disorder confidence

. . . . . . . . . 970 . . . . . . . . . 980 . . . . . . . . . 990 . . . . . . . . . 1000 . . . . . . . . . 1010 . . . . . . . . . 1020

Sequence G R A V L S Q E Q D G I K S H T H S A S A S S T D L G T K T T S S F D Y G T K S T N N T G A H T H S V S G S T N S A G A

Secondary structure

SS confidence

Disorder
?
? ?
? ?
? ?
? ? ? ? ? ? ?
? ? ? ? ? ? ? ? ? ? ?

Disorder confidence

. . . . . . . . . 1030 . . . . . . . . . 1040 . . . . . . . . . 1050 . . . . . . . . . 1060 . . . . . . . . . 1070 . . . . . . . . . 1080

Sequence H T H S L A N V N T A S A N S G A G S A S T R L S V V H N Q N Y A T S S A G A H T H S L S G T A A S A G A H A H T V G I

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?
?
? ? ? ? ? ? ? ? ? ? ? ? ?
?

Disorder confidence

. . . . . . . . . 1090 . . . . . . . . . 1100 . . . . . . . . . 1110 . . . . . . . . . 1120

Sequence G A H T H S V A I G S H G H T I T V N A A G N A E N T V K N I A F N Y I V R L A

Secondary structure

SS confidence

Disorder
? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

PDB 2xgf chain A

Region: 902 - 1120
Aligned: 216
Modelled: 219
Confidence: 98.6%
Identity: 70%
PDB header:viral protein
Chain: A: PDB Molecule:long tail fiber protein p37;
PDBTitle: structure of the bacteriophage t4 long tail fibre needle-2 shaped receptor-binding tip

Phyre2

PDB 3mn8 chain A

Region: 5 - 93
Aligned: 80
Modelled: 89
Confidence: 98.3%
Identity: 20%
PDB header:hydrolase
Chain: A: PDB Molecule:lp15968p;
PDBTitle: structure of drosophila melanogaster carboxypeptidase d isoform 1b2 short

Phyre2

PDB 1h8l chain A domain 1

Region: 5 - 92
Aligned: 76
Modelled: 78
Confidence: 98.2%
Identity: 25%
Fold: Prealbumin-like
Superfamily: Carboxypeptidase regulatory domain-like
Family: Carboxypeptidase regulatory domain

Phyre2

PDB 1uwy chain A domain 1

Region: 5 - 104
Aligned: 91
Modelled: 100
Confidence: 98.2%
Identity: 19%
Fold: Prealbumin-like
Superfamily: Carboxypeptidase regulatory domain-like
Family: Carboxypeptidase regulatory domain

Phyre2

PDB 2nsm chain A

Region: 5 - 92
Aligned: 76
Modelled: 88
Confidence: 98.0%
Identity: 26%
PDB header:hydrolase
Chain: A: PDB Molecule:carboxypeptidase n catalytic chain;
PDBTitle: crystal structure of the human carboxypeptidase n (kininase i)2 catalytic domain

Phyre2

PDB 1h8l chain A

Region: 5 - 92
Aligned: 76
Modelled: 88
Confidence: 97.9%
Identity: 28%
PDB header:carboxypeptidase
Chain: A: PDB Molecule:carboxypeptidase gp180 residues 503-882;
PDBTitle: duck carboxypeptidase d domain ii in complex with gemsa

Phyre2

PDB 1uwy chain A

Region: 5 - 86
Aligned: 73
Modelled: 82
Confidence: 97.9%
Identity: 21%
PDB header:hydrolase
Chain: A: PDB Molecule:carboxypeptidase m;
PDBTitle: crystal structure of human carboxypeptidase m

Phyre2

PDB 1nkg chain A domain 1

Region: 4 - 91
Aligned: 76
Modelled: 88
Confidence: 97.3%
Identity: 12%
Fold: Prealbumin-like
Superfamily: Starch-binding domain-like
Family: Rhamnogalacturonase B, RhgB, middle domain

Phyre2

PDB 1cwv chain A domain 2

Region: 1 - 78
Aligned: 70
Modelled: 76
Confidence: 96.0%
Identity: 26%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 1cwv chain A

Region: 1 - 66
Aligned: 62
Modelled: 66
Confidence: 95.6%
Identity: 21%
PDB header:structural protein
Chain: A: PDB Molecule:invasin;
PDBTitle: crystal structure of invasin: a bacterial integrin-binding protein

Phyre2

PDB 1f00 chain I domain 1

Region: 2 - 78
Aligned: 71
Modelled: 77
Confidence: 95.2%
Identity: 18%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 1ocy chain A

Region: 1049 - 1120
Aligned: 72
Modelled: 72
Confidence: 95.1%
Identity: 13%
Fold: Receptor-binding domain of short tail fibre protein gp12
Superfamily: Receptor-binding domain of short tail fibre protein gp12
Family: Receptor-binding domain of short tail fibre protein gp12

Phyre2

PDB 3pcc chain M

Region: 3 - 103
Aligned: 101
Modelled: 101
Confidence: 94.9%
Identity: 17%
Fold: Prealbumin-like
Superfamily: Aromatic compound dioxygenase
Family: Aromatic compound dioxygenase

Phyre2

PDB 1s9a chain A

Region: 3 - 60
Aligned: 58
Modelled: 58
Confidence: 94.8%
Identity: 16%
Fold: Prealbumin-like
Superfamily: Aromatic compound dioxygenase
Family: Aromatic compound dioxygenase

Phyre2

PDB 1cwv chain A domain 1

Region: 2 - 71
Aligned: 66
Modelled: 70
Confidence: 94.7%
Identity: 21%
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Invasin/intimin cell-adhesion fragments
Family: Invasin/intimin cell-adhesion fragments

Phyre2

PDB 2azq chain A

Region: 3 - 60
Aligned: 58
Modelled: 58
Confidence: 94.6%
Identity: 24%
PDB header:oxidoreductase
Chain: A: PDB Molecule:catechol 1,2-dioxygenase;
PDBTitle: crystal structure of catechol 1,2-dioxygenase from pseudomonas arvilla2 c-1

Phyre2

PDB 2bur chain B domain 1

Region: 3 - 103
Aligned: 101
Modelled: 101
Confidence: 94.3%
Identity: 16%
Fold: Prealbumin-like
Superfamily: Aromatic compound dioxygenase
Family: Aromatic compound dioxygenase

Phyre2

PDB 1dmh chain A

Region: 3 - 60
Aligned: 58
Modelled: 58
Confidence: 94.2%
Identity: 22%
Fold: Prealbumin-like
Superfamily: Aromatic compound dioxygenase
Family: Aromatic compound dioxygenase

Phyre2

PDB 3irp chain X

Region: 9 - 65
Aligned: 51
Modelled: 57
Confidence: 93.8%
Identity: 24%
PDB header:cell adhesion
Chain: X: PDB Molecule:uro-adherence factor a;
PDBTitle: crystal structure of functional region of uafa from staphylococcus2 saprophyticus at 1.50 angstrom resolution

Phyre2

PDB 3n9t chain A

Region: 3 - 60
Aligned: 58
Modelled: 58
Confidence: 93.5%
Identity: 17%
PDB header:oxidoreductase
Chain: A: PDB Molecule:pnpc;
PDBTitle: cryatal structure of hydroxyquinol 1,2-dioxygenase from pseudomonas2 putida dll-e4