Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	N	N	D	L	V	A	K	L	W	K	L	C	D	N	L	R	D	G	G	V	S	Y	Q	N	Y	V	N	E	L	A	S	L	L	F	L	K	M	C	K	E	T	G	Q	E	A	E	Y	L	P	E	G	Y	R	W	D	D	L	K
Secondary structure
SS confidence
Disorder		?	?																																											?	?				?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		S	R	I	G	Q	E	Q	L	Q	F	Y	R	K	M	L	V	H	L	G	E	D	D	K	K	L	V	Q	A	V	F	H	N	V	S	T	T	I	T	E	P	K	Q	I	T	A	L	V	S	N	M	D	S	L	D	W	Y	N	G	A	H
Secondary structure
SS confidence
Disorder			?																																		?																	?	?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	K	S	R	D	D	F	G	D	M	Y	E	G	L	L	Q	K	N	A	N	E	T	K	S	G	A	G	Q	Y	F	T	P	R	P	L	I	K	T	I	I	H	L	L	K	P	Q	P	R	E	V	V	Q	D	P	A	A	G	T	A	G
Secondary structure
SS confidence
Disorder		?	?																		?	?	?	?	?	?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		F	L	I	E	A	D	R	Y	V	K	S	Q	T	N	D	L	D	D	L	D	G	D	T	Q	D	F	Q	I	H	R	A	F	I	G	L	E	L	V	P	G	T	R	R	L	A	L	M	N	C	L	L	H	D	I	E	G	N	L	D	H
Secondary structure
SS confidence
Disorder																?	?	?	?	?			?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		G	G	A	I	R	L	G	N	T	L	G	S	D	G	E	N	L	P	K	A	H	I	V	A	T	N	P	P	F	G	S	A	A	G	T	N	I	T	R	T	F	V	H	P	T	S	N	K	Q	L	C	F	M	Q	H	I	I	E	T	L
Secondary structure
SS confidence
Disorder																																?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		H	P	G	G	R	A	A	V	V	V	P	D	N	V	L	F	E	G	G	K	G	T	D	I	R	R	D	L	M	D	K	C	H	L	H	T	I	L	R	L	P	T	G	I	F	Y	A	Q	G	V	K	T	N	V	L	F	F	T	K	G
Secondary structure
SS confidence
Disorder															?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		T	V	A	N	P	N	Q	D	K	N	C	T	D	D	V	W	V	Y	D	L	R	T	N	M	P	S	F	G	K	R	T	P	F	T	D	E	H	L	Q	P	F	E	R	V	Y	G	E	D	P	H	G	L	S	P	R	T	E	G	E	W
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?		?										?	?	?	?	?	?	?	?	?		?	?																	?	?	?	?	?	?	?			?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		S	F	N	A	E	E	T	E	V	A	D	S	E	E	N	K	N	T	D	Q	H	L	A	T	S	R	W	R	K	F	S	R	E	W	I	R	T	A	K	S	D	S	L	D	I	S	W	L	K	D	K	D	S	I	D	A	D	S	L	P
Secondary structure
SS confidence
Disorder																																						?	?		?												?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.
Sequence		E	P	D	V	L	A	A	E	A	M	G	E	L	V	Q	A	L	S	E	L	D	A	L	M	R	E	L	G	A	S	D	E	A	D	L	Q	R	Q	L	L	E	E	A	F	G	G	V	K	E
Secondary structure
SS confidence
Disorder		?																												?	?	?	?	?											?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2ar0 chain A domain 1 Region: 4 - 527 Aligned: 485 Modelled: 492 Confidence: 100.0% Identity: 96% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N-6 DNA Methylase-like Phyre2 PDB 2okc chain A domain 1 Region: 4 - 471 Aligned: 418 Modelled: 443 Confidence: 100.0% Identity: 38% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N-6 DNA Methylase-like Phyre2 PDB 3lkd chain B Region: 2 - 447 Aligned: 401 Modelled: 416 Confidence: 100.0% Identity: 25% PDB header:transferase Chain: B: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of the type i restriction-modification2 system methyltransferase subunit from streptococcus3 thermophilus, northeast structural genomics consortium4 target sur80 Phyre2 PDB 3khk chain A Region: 4 - 447 Aligned: 416 Modelled: 444 Confidence: 100.0% Identity: 24% PDB header:dna binding protein Chain: A: PDB Molecule:type i restriction-modification system PDBTitle: crystal structure of type-i restriction-modification system2 methylation subunit (mm_0429) from methanosarchina mazei. Phyre2 PDB 2f8l chain A domain 1 Region: 65 - 408 Aligned: 302 Modelled: 323 Confidence: 100.0% Identity: 19% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N-6 DNA Methylase-like Phyre2 PDB 3s1s chain A Region: 4 - 365 Aligned: 331 Modelled: 347 Confidence: 100.0% Identity: 18% PDB header:hydrolase, transferase Chain: A: PDB Molecule:restriction endonuclease bpusi; PDBTitle: characterization and crystal structure of the type iig restriction2 endonuclease bpusi Phyre2 PDB 1g38 chain A Region: 150 - 403 Aligned: 218 Modelled: 223 Confidence: 100.0% Identity: 19% PDB header:transferase/dna Chain: A: PDB Molecule:modification methylase taqi; PDBTitle: adenine-specific methyltransferase m. taq i/dna complex Phyre2 PDB 1aqj chain B Region: 150 - 363 Aligned: 178 Modelled: 183 Confidence: 100.0% Identity: 21% PDB header:methyltransferase Chain: B: PDB Molecule:adenine-n6-dna-methyltransferase taqi; PDBTitle: structure of adenine-n6-dna-methyltransferase taqi Phyre2 PDB 2ih2 chain A domain 1 Region: 150 - 387 Aligned: 202 Modelled: 205 Confidence: 100.0% Identity: 20% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: DNA methylase TaqI, N-terminal domain Phyre2 PDB 3ldg chain A Region: 153 - 351 Aligned: 179 Modelled: 195 Confidence: 99.8% Identity: 19% PDB header:transferase Chain: A: PDB Molecule:putative uncharacterized protein smu.472; PDBTitle: crystal structure of smu.472, a putative methyltransferase complexed2 with sah Phyre2 PDB 3ldu chain A Region: 152 - 338 Aligned: 171 Modelled: 187 Confidence: 99.8% Identity: 15% PDB header:transferase Chain: A: PDB Molecule:putative methylase; PDBTitle: the crystal structure of a possible methylase from2 clostridium difficile 630. Phyre2 PDB 3k0b chain A Region: 153 - 315 Aligned: 147 Modelled: 160 Confidence: 99.8% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:predicted n6-adenine-specific dna methylase; PDBTitle: crystal structure of a predicted n6-adenine-specific dna methylase2 from listeria monocytogenes str. 4b f2365 Phyre2 PDB 1wy7 chain A domain 1 Region: 131 - 359 Aligned: 181 Modelled: 210 Confidence: 99.7% Identity: 22% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: Ta1320-like Phyre2 PDB 3fux chain B Region: 129 - 364 Aligned: 189 Modelled: 199 Confidence: 99.7% Identity: 14% PDB header:transferase Chain: B: PDB Molecule:dimethyladenosine transferase; PDBTitle: t. thermophilus 16s rrna a1518 and a1519 methyltransferase (ksga) in2 complex with 5'-methylthioadenosine in space group p212121 Phyre2 PDB 1nv8 chain A Region: 149 - 313 Aligned: 142 Modelled: 146 Confidence: 99.7% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: N5-glutamine methyltransferase, HemK Phyre2 PDB 3evz chain A Region: 150 - 360 Aligned: 167 Modelled: 193 Confidence: 99.6% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:methyltransferase; PDBTitle: crystal strucure of methyltransferase from pyrococcus furiosus Phyre2 PDB 1zq9 chain A domain 1 Region: 149 - 363 Aligned: 171 Modelled: 178 Confidence: 99.6% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: rRNA adenine dimethylase-like Phyre2 PDB 1qyr chain A Region: 149 - 362 Aligned: 170 Modelled: 177 Confidence: 99.6% Identity: 15% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: rRNA adenine dimethylase-like Phyre2 PDB 3gdh chain C Region: 151 - 314 Aligned: 136 Modelled: 144 Confidence: 99.5% Identity: 20% PDB header:transferase Chain: C: PDB Molecule:trimethylguanosine synthase homolog; PDBTitle: methyltransferase domain of human trimethylguanosine2 synthase 1 (tgs1) bound to m7gtp and adenosyl-homocysteine3 (active form) Phyre2 PDB 2ozv chain A Region: 156 - 315 Aligned: 125 Modelled: 123 Confidence: 99.5% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:hypothetical protein atu0636; PDBTitle: crystal structure of a predicted o-methyltransferase, protein atu6362 from agrobacterium tumefaciens. Phyre2 1 d2ar0a1 2 d2okca1 3 c3lkdB_ 4 c3khkA_ 5 d2f8la1 6 c3s1sA_ 7 c1g38A_ 8 c1aqjB_ 9 d2ih2a1 10 c3ldgA_ 11 c3lduA_ 12 c3k0bA_ 13 d1wy7a1 14 c3fuxB_ 15 d1nv8a_ 16 c3evzA_ 17 d1zq9a1 18 d1qyra_ 19 c3gdhC_ 20 c2ozvA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338