Secondary structure and disorder prediction

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Sequence		M	H	F	A	Q	R	V	R	A	L	V	V	L	N	G	V	A	L	L	P	Q	F	A	C	K	Q	G	L	A	N	G	E	L	V	R	L	F	A	P	W	S	G	I	P	R	P	L	Y	A	L	F	A	G	R	K	G	M	P	A	I
Secondary structure
SS confidence
Disorder		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.
Sequence		A	R	Y	F	M	D	E	L	T	T	R	L	A	N	G	V
Secondary structure
SS confidence
Disorder														?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3hhf chain B Region: 2 - 73 Aligned: 72 Modelled: 71 Confidence: 99.3% Identity: 22% PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: structure of crga regulatory domain, a lysr-type transcriptional2 regulator from neisseria meningitidis. Phyre2 PDB 3mz1 chain D Region: 1 - 74 Aligned: 74 Modelled: 71 Confidence: 99.3% Identity: 23% PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator; PDBTitle: the crystal structure of a possible transcription regulator protein2 from sinorhizobium meliloti 1021 Phyre2 PDB 3t1b chain B Region: 2 - 72 Aligned: 71 Modelled: 71 Confidence: 99.2% Identity: 25% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: crystal structure of the full-length aphb n100e variant Phyre2 PDB 3kos chain A Region: 2 - 74 Aligned: 72 Modelled: 73 Confidence: 99.2% Identity: 18% PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional activator ampr; PDBTitle: structure of the ampr effector binding domain from citrobacter2 freundii Phyre2 PDB 3fd3 chain A Region: 2 - 71 Aligned: 67 Modelled: 70 Confidence: 99.2% Identity: 18% PDB header:transcription regulator Chain: A: PDB Molecule:chromosome replication initiation inhibitor protein; PDBTitle: structure of the c-terminal domains of a lysr family protein from2 agrobacterium tumefaciens str. c58. Phyre2 PDB 3hhg chain F Region: 2 - 73 Aligned: 72 Modelled: 72 Confidence: 99.2% Identity: 24% PDB header:transcription regulator Chain: F: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: structure of crga, a lysr-type transcriptional regulator from2 neisseria meningitidis. Phyre2 PDB 2qsx chain B Region: 1 - 73 Aligned: 73 Modelled: 73 Confidence: 99.2% Identity: 21% PDB header:transcription Chain: B: PDB Molecule:putative transcriptional regulator, lysr family; PDBTitle: crystal structure of putative transcriptional regulator lysr from2 vibrio parahaemolyticus Phyre2 PDB 3fzj chain C Region: 2 - 71 Aligned: 70 Modelled: 70 Confidence: 99.1% Identity: 9% PDB header:transcription regulator Chain: C: PDB Molecule:lysr type regulator of tsambcd; PDBTitle: tsar low resolution crystal structure, tetragonal form Phyre2 PDB 1uth chain A Region: 2 - 75 Aligned: 74 Modelled: 74 Confidence: 99.1% Identity: 11% Fold: Periplasmic binding protein-like II Superfamily: Periplasmic binding protein-like II Family: Phosphate binding protein-like Phyre2 PDB 1al3 chain A Region: 2 - 73 Aligned: 71 Modelled: 72 Confidence: 99.0% Identity: 14% PDB header:transcription regulation Chain: A: PDB Molecule:cys regulon transcriptional activator cysb; PDBTitle: cofactor binding fragment of cysb from klebsiella aerogenes Phyre2 PDB 1al3 chain A Region: 2 - 73 Aligned: 71 Modelled: 72 Confidence: 99.0% Identity: 14% Fold: Periplasmic binding protein-like II Superfamily: Periplasmic binding protein-like II Family: Phosphate binding protein-like Phyre2 PDB 2uye chain A Region: 2 - 75 Aligned: 74 Modelled: 74 Confidence: 99.0% Identity: 11% PDB header:transcription Chain: A: PDB Molecule:regulatory protein; PDBTitle: double mutant y110s,f111v dntr from burkholderia sp. strain2 dnt in complex with thiocyanate Phyre2 PDB 3oxn chain D Region: 2 - 74 Aligned: 73 Modelled: 73 Confidence: 99.0% Identity: 11% PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator, lysr family; PDBTitle: the crystal structure of a putative transcriptional regulator from2 vibrio parahaemolyticus Phyre2 PDB 3fzv chain C Region: 2 - 73 Aligned: 72 Modelled: 72 Confidence: 99.0% Identity: 18% PDB header:transcription regulator Chain: C: PDB Molecule:probable transcriptional regulator; PDBTitle: crystal structure of pa01 protein, putative lysr family2 transcriptional regulator from pseudomonas aeruginosa Phyre2 PDB 1i6a chain A Region: 2 - 74 Aligned: 73 Modelled: 73 Confidence: 98.9% Identity: 14% Fold: Periplasmic binding protein-like II Superfamily: Periplasmic binding protein-like II Family: Phosphate binding protein-like Phyre2 PDB 2hxr chain A Region: 2 - 73 Aligned: 69 Modelled: 72 Confidence: 98.9% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator cynr; PDBTitle: structure of the ligand binding domain of e. coli cynr, a2 transcriptional regulator controlling cyanate metabolism Phyre2 PDB 3isp chain A Region: 2 - 74 Aligned: 69 Modelled: 73 Confidence: 98.9% Identity: 16% PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator PDBTitle: crystal structure of argp from mycobacterium tuberculosis Phyre2 PDB 3jv9 chain B Region: 2 - 76 Aligned: 74 Modelled: 75 Confidence: 98.9% Identity: 9% PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: the structure of a reduced form of oxyr from n. meningitidis Phyre2 PDB 1iz1 chain B Region: 2 - 74 Aligned: 70 Modelled: 73 Confidence: 98.8% Identity: 11% PDB header:dna binding protein Chain: B: PDB Molecule:lysr-type regulatory protein; PDBTitle: crystal structure of cbnr, a lysr family transcriptional2 regulator Phyre2 PDB 3n6u chain A Region: 2 - 71 Aligned: 70 Modelled: 70 Confidence: 98.8% Identity: 9% PDB header:transcription regulator Chain: A: PDB Molecule:lysr type regulator of tsambcd; PDBTitle: effector binding domain of tsar in complex with its inducer p-2 toluenesulfonate Phyre2 1 c3hhfB_ 2 c3mz1D_ 3 c3t1bB_ 4 c3kosA_ 5 c3fd3A_ 6 c3hhgF_ 7 c2qsxB_ 8 c3fzjC_ 9 d1utha_ 10 c1al3A_ 11 d1al3a_ 12 c2uyeA_ 13 c3oxnD_ 14 c3fzvC_ 15 d1i6aa_ 16 c2hxrA_ 17 c3ispA_ 18 c3jv9B_ 19 c1iz1B_ 20 c3n6uA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3hhfB_ 99.3 22 PDB header:transcription regulator Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: structure of crga regulatory domain, a lysr-type transcriptional2 regulator from neisseria meningitidis. 2 c3mz1D_ 99.3 23 PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator; PDBTitle: the crystal structure of a possible transcription regulator protein2 from sinorhizobium meliloti 1021 3 c3t1bB_ 99.2 25 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: crystal structure of the full-length aphb n100e variant 4 c3kosA_ 99.2 18 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional activator ampr; PDBTitle: structure of the ampr effector binding domain from citrobacter2 freundii 5 c3fd3A_ 99.2 18 PDB header:transcription regulator Chain: A: PDB Molecule:chromosome replication initiation inhibitor protein; PDBTitle: structure of the c-terminal domains of a lysr family protein from2 agrobacterium tumefaciens str. c58. 6 c3hhgF_ 99.2 24 PDB header:transcription regulator Chain: F: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: structure of crga, a lysr-type transcriptional regulator from2 neisseria meningitidis. 7 c2qsxB_ 99.2 21 PDB header:transcription Chain: B: PDB Molecule:putative transcriptional regulator, lysr family; PDBTitle: crystal structure of putative transcriptional regulator lysr from2 vibrio parahaemolyticus 8 c3fzjC_ 99.1 9 PDB header:transcription regulator Chain: C: PDB Molecule:lysr type regulator of tsambcd; PDBTitle: tsar low resolution crystal structure, tetragonal form 9 d1utha_ 99.1 11 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 10 c1al3A_ 99.0 14 PDB header:transcription regulation Chain: A: PDB Molecule:cys regulon transcriptional activator cysb; PDBTitle: cofactor binding fragment of cysb from klebsiella aerogenes 11 d1al3a_ 99.0 14 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 12 c2uyeA_ 99.0 11 PDB header:transcription Chain: A: PDB Molecule:regulatory protein; PDBTitle: double mutant y110s,f111v dntr from burkholderia sp. strain2 dnt in complex with thiocyanate 13 c3oxnD_ 99.0 11 PDB header:transcription regulator Chain: D: PDB Molecule:putative transcriptional regulator, lysr family; PDBTitle: the crystal structure of a putative transcriptional regulator from2 vibrio parahaemolyticus 14 c3fzvC_ 99.0 18 PDB header:transcription regulator Chain: C: PDB Molecule:probable transcriptional regulator; PDBTitle: crystal structure of pa01 protein, putative lysr family2 transcriptional regulator from pseudomonas aeruginosa 15 d1i6aa_ 98.9 14 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 16 c2hxrA_ 98.9 16 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator cynr; PDBTitle: structure of the ligand binding domain of e. coli cynr, a2 transcriptional regulator controlling cyanate metabolism 17 c3ispA_ 98.9 16 PDB header:transcription Chain: A: PDB Molecule:hth-type transcriptional regulator PDBTitle: crystal structure of argp from mycobacterium tuberculosis 18 c3jv9B_ 98.9 9 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator, lysr family; PDBTitle: the structure of a reduced form of oxyr from n. meningitidis 19 c1iz1B_ 98.8 11 PDB header:dna binding protein Chain: B: PDB Molecule:lysr-type regulatory protein; PDBTitle: crystal structure of cbnr, a lysr family transcriptional2 regulator 20 c3n6uA_ 98.8 9 PDB header:transcription regulator Chain: A: PDB Molecule:lysr type regulator of tsambcd; PDBTitle: effector binding domain of tsar in complex with its inducer p-2 toluenesulfonate 21 c2ql3G_ not modelled 98.8 17 PDB header:transcription Chain: G: PDB Molecule:probable transcriptional regulator, lysr family protein; PDBTitle: crystal structure of the c-terminal domain of a probable lysr family2 transcriptional regulator from rhodococcus sp. rha1 22 d2fyia1 not modelled 98.7 10 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 23 c3ho7A_ not modelled 98.7 9 PDB header:transcription Chain: A: PDB Molecule:oxyr; PDBTitle: crystal structure of oxyr from porphyromonas gingivalis 24 c2h9qC_ not modelled 98.7 11 PDB header:transcription Chain: C: PDB Molecule:hth-type transcriptional regulator catm; PDBTitle: crystal structure of the effector binding domain of a catm2 variant (r156h) 25 d1ixca2 not modelled 98.6 11 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 26 c2f7cA_ not modelled 98.5 11 PDB header:gene regulation Chain: A: PDB Molecule:hth-type transcriptional regulator catm; PDBTitle: catm effector binding domain with its effector cis,cis-muconate 27 d2esna2 not modelled 98.5 13 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 28 c2h9bB_ not modelled 98.4 14 PDB header:transcription Chain: B: PDB Molecule:hth-type transcriptional regulator benm; PDBTitle: crystal structure of the effector binding domain of a benm variant2 (benm r156h/t157s) 29 c2f78A_ not modelled 98.3 16 PDB header:gene regulation Chain: A: PDB Molecule:hth-type transcriptional regulator benm; PDBTitle: benm effector binding domain with its effector benzoate 30 c2esnC_ not modelled 98.2 12 PDB header:structural genomics, unknown function Chain: C: PDB Molecule:probable transcriptional regulator; PDBTitle: the crystal structure of probable transcriptional regulator pa04772 from pseudomonas aeruginosa 31 c3onmB_ not modelled 97.3 10 PDB header:transcription Chain: B: PDB Molecule:transcriptional regulator lrha; PDBTitle: effector binding domain of lysr-type transcription factor rovm from y.2 pseudotuberculosis 32 d1twya_ not modelled 50.5 7 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 33 c1twyG_ not modelled 45.9 7 PDB header:structural genomics, unknown function Chain: G: PDB Molecule:abc transporter, periplasmic substrate-binding protein; PDBTitle: crystal structure of an abc-type phosphate transport receptor from2 vibrio cholerae 34 c3c5tB_ not modelled 41.9 30 PDB header:signaling protein/signaling protein Chain: B: PDB Molecule:exendin-4; PDBTitle: crystal structure of the ligand-bound glucagon-like peptide-1 receptor2 extracellular domain 35 c3lr1A_ not modelled 32.2 8 PDB header:transport protein Chain: A: PDB Molecule:tungstate abc transporter, periplasmic tungstate- PDBTitle: the crystal structure of the tungstate abc transporter from2 geobacter sulfurreducens 36 d1amfa_ not modelled 16.0 11 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 37 c3muqB_ not modelled 14.9 15 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:uncharacterized conserved protein; PDBTitle: the crystal structure of a conserved functionally unknown protein from2 vibrio parahaemolyticus rimd 2210633 38 d2i7xa1 not modelled 11.3 14 Fold:Metallo-hydrolase/oxidoreductase Superfamily:Metallo-hydrolase/oxidoreductase Family:beta-CASP RNA-metabolising hydrolases 39 c2i7xA_ not modelled 11.3 14 PDB header:rna binding protein, protein binding Chain: A: PDB Molecule:protein cft2; PDBTitle: structure of yeast cpsf-100 (ydh1p) 40 c1jrjA_ not modelled 11.1 18 PDB header:hormone/growth factor Chain: A: PDB Molecule:exendin-4; PDBTitle: solution structure of exendin-4 in 30-vol% trifluoroethanol 41 d1atga_ not modelled 10.6 13 Fold:Periplasmic binding protein-like II Superfamily:Periplasmic binding protein-like II Family:Phosphate binding protein-like 42 c3cvgC_ not modelled 10.5 14 PDB header:metal binding protein Chain: C: PDB Molecule:putative metal binding protein; PDBTitle: crystal structure of a periplasmic putative metal binding protein 43 c1d0rA_ not modelled 6.9 27 PDB header:hormone/growth factor Chain: A: PDB Molecule:glucagon-like peptide-1-(7-36)-amide; PDBTitle: solution structure of glucagon-like peptide-1-(7-36)-amide2 in trifluoroethanol/water 44 c2h5yC_ not modelled 6.4 12 PDB header:metal transport Chain: C: PDB Molecule:molybdate-binding periplasmic protein; PDBTitle: crystallographic structure of the molybdate-binding protein of2 xanthomonas citri at 1.7 ang resolution bound to molybdate

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0