Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP45522
DateThu Jan 5 12:02:52 GMT 2012
Unique Job ID5a3a0844cb93b6d8

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3eywA_
Top template information
PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
Confidence and coverage
Confidence:100.0% Coverage: 26%
159 residues ( 26% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
560 residues ( 93%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFS
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Disorder  ????





















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   .........70.........80.........90.........100.........110.........120
Sequence  ELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALLAGLLMLTDFAWQAAVVGG
Secondary structure 




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??



































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   .........130.........140.........150.........160.........170.........180
Sequence  IGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDW
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?????



























??
??




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   .........190.........200.........210.........220.........230.........240
Sequence  MKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLGSALFMDALGLSMA
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   .........250.........260.........270.........280.........290.........300
Sequence  LGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVVISVVV
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?












































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   .........310.........320.........330.........340.........350.........360
Sequence  LVAVKILVLYLLARLYGVRSSERMQFAGVLSQGGEFAFVLFSTASSQRLFQGDQMALLLV
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   .........370.........380.........390.........400.........410.........420
Sequence  TVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDEKPWVNDDKPQVIVVGFGRFGQVIGRLLM
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????????????????????




















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   .........430.........440.........450.........460.........470.........480
Sequence  ANKMRITVLERDISAVNLMRKYGYKVYYGDATQVDLLRSAGAEAAESIVITCNEPEDTMK
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   .........490.........500.........510.........520.........530.........540
Sequence  LVEICQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVTLGMHPHQ
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   .........550.........560.........570.........580.........590.........600
Sequence  AQRAQLHFRRLDMRMLRELIPMHADTVQISRAREARRELEEIFQREMQQERRQLDGWDEF
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??????






















???????????
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   .
Sequence  E
Secondary structure 
SS confidence 
Disorder  ?
Disorder confidence 
 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3eyw chain A

3D model

Region: 402 - 560
Aligned: 159
Modelled: 159
Confidence: 100.0%
Identity: 45%
PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff

Phyre2

PDB 1zcd chain A

3D model

Region: 11 - 379
Aligned: 347
Modelled: 349
Confidence: 99.9%
Identity: 17%
PDB header:membrane protein
Chain: A: PDB Molecule:na(+)/h(+) antiporter 1;
PDBTitle: crystal structure of the na+/h+ antiporter nhaa

Phyre2

PDB 3fwz chain A

3D model

Region: 395 - 530
Aligned: 136
Modelled: 136
Confidence: 99.9%
Identity: 22%
PDB header:membrane protein
Chain: A: PDB Molecule:inner membrane protein ybal;
PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli

Phyre2

PDB 3c85 chain A

3D model

Region: 395 - 535
Aligned: 141
Modelled: 141
Confidence: 99.9%
Identity: 21%
PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus

Phyre2

PDB 1id1 chain A

3D model

Region: 398 - 543
Aligned: 145
Modelled: 146
Confidence: 99.8%
Identity: 12%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 1lss chain A

3D model

Region: 402 - 530
Aligned: 128
Modelled: 129
Confidence: 99.8%
Identity: 18%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 2hmv chain A domain 1

3D model

Region: 401 - 532
Aligned: 132
Modelled: 132
Confidence: 99.8%
Identity: 17%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 3llv chain A

3D model

Region: 400 - 530
Aligned: 130
Modelled: 131
Confidence: 99.8%
Identity: 18%
PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a

Phyre2

PDB 2fy8 chain A domain 1

3D model

Region: 401 - 528
Aligned: 126
Modelled: 128
Confidence: 99.8%
Identity: 20%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 2g1u chain A

3D model

Region: 398 - 531
Aligned: 133
Modelled: 134
Confidence: 99.8%
Identity: 15%
PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution

Phyre2

PDB 2fy8 chain A

3D model

Region: 400 - 531
Aligned: 130
Modelled: 132
Confidence: 99.7%
Identity: 19%
PDB header:transport protein
Chain: A: PDB Molecule:calcium-gated potassium channel mthk;
PDBTitle: crystal structure of mthk rck domain in its ligand-free gating-ring2 form

Phyre2

PDB 3l4b chain G

3D model

Region: 402 - 530
Aligned: 129
Modelled: 129
Confidence: 99.7%
Identity: 15%
PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima

Phyre2

PDB 1lnq chain C

3D model

Region: 338 - 528
Aligned: 172
Modelled: 174
Confidence: 99.7%
Identity: 17%
PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a

Phyre2

PDB 3u6n chain C

3D model

Region: 401 - 531
Aligned: 131
Modelled: 131
Confidence: 99.3%
Identity: 17%
PDB header:transport protein
Chain: C: PDB Molecule:high-conductance ca2+-activated k+ channel protein;
PDBTitle: open structure of the bk channel gating ring

Phyre2

PDB 3mt5 chain A

3D model

Region: 401 - 531
Aligned: 131
Modelled: 131
Confidence: 99.3%
Identity: 16%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:potassium large conductance calcium-activated channel,
PDBTitle: crystal structure of the human bk gating apparatus

Phyre2

PDB 3naf chain A

3D model

Region: 396 - 531
Aligned: 136
Modelled: 136
Confidence: 98.9%
Identity: 15%
PDB header:ion transport
Chain: A: PDB Molecule:calcium-activated potassium channel subunit alpha-1;
PDBTitle: structure of the intracellular gating ring from the human high-2 conductance ca2+ gated k+ channel (bk channel)

Phyre2

PDB 1e5q chain A domain 1

3D model

Region: 400 - 530
Aligned: 129
Modelled: 131
Confidence: 98.4%
Identity: 9%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain

Phyre2

PDB 3ktd chain C

3D model

Region: 398 - 597
Aligned: 193
Modelled: 200
Confidence: 98.4%
Identity: 15%
PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution

Phyre2

PDB 1pjq chain A domain 1

3D model

Region: 399 - 489
Aligned: 85
Modelled: 91
Confidence: 98.1%
Identity: 12%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Siroheme synthase N-terminal domain-like

Phyre2

PDB 3ic5 chain A

3D model

Region: 397 - 510
Aligned: 110
Modelled: 114
Confidence: 98.1%
Identity: 19%
PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.

Phyre2

PDB 1pjc chain A domain 1

3D model

Region: 382 - 473
Aligned: 91
Modelled: 91
Confidence: 97.8%
Identity: 8%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Formate/glycerate dehydrogenases, NAD-domain

Phyre2
1

c3eywA_
2

c1zcdA_
3

c3fwzA_
4

c3c85A_
5

d1id1a_
6

d1lssa_
7

d2hmva1
8

c3llvA_
9

d2fy8a1
10

c2g1uA_
11

c2fy8A_
12

c3l4bG_
13

c1lnqC_
14

c3u6nC_
15

c3mt5A_
16

c3nafA_
17

d1e5qa1
18

c3ktdC_
19

d1pjqa1
20

c3ic5A_
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d1pjca1
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3eywA_



100.0 45 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
2c1zcdA_



99.9 17 PDB header:membrane protein
Chain: A: PDB Molecule:na(+)/h(+) antiporter 1;
PDBTitle: crystal structure of the na+/h+ antiporter nhaa
3c3fwzA_



99.9 22 PDB header:membrane protein
Chain: A: PDB Molecule:inner membrane protein ybal;
PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli
4c3c85A_



99.9 21 PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus
5d1id1a_



99.8 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
6d1lssa_



99.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
7d2hmva1



99.8 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
8c3llvA_



99.8 18 PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a
9d2fy8a1



99.8 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
10c2g1uA_



99.8 15 PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution
11c2fy8A_



99.7 19 PDB header:transport protein
Chain: A: PDB Molecule:calcium-gated potassium channel mthk;
PDBTitle: crystal structure of mthk rck domain in its ligand-free gating-ring2 form
12c3l4bG_



99.7 15 PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima
13c1lnqC_



99.7 17 PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a
14c3u6nC_



99.3 17 PDB header:transport protein
Chain: C: PDB Molecule:high-conductance ca2+-activated k+ channel protein;
PDBTitle: open structure of the bk channel gating ring
15c3mt5A_



99.3 16 PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:potassium large conductance calcium-activated channel,
PDBTitle: crystal structure of the human bk gating apparatus
16c3nafA_



98.9 15 PDB header:ion transport
Chain: A: PDB Molecule:calcium-activated potassium channel subunit alpha-1;
PDBTitle: structure of the intracellular gating ring from the human high-2 conductance ca2+ gated k+ channel (bk channel)
17d1e5qa1



98.4 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
18c3ktdC_



98.4 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
19d1pjqa1



98.1 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
20c3ic5A_



98.1 19 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
21d2pgda2



not modelled 98.0 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
22d2f1ka2



not modelled 97.9 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
23c3fwnB_



not modelled 97.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
24c3cumA_



not modelled 97.8 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:probable 3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase2 from pseudomonas aeruginosa pao1
25d1pjca1



97.8 8 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
26c3l6dB_



not modelled 97.8 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of putative oxidoreductase from pseudomonas putida2 kt2440
27c1pgjA_



not modelled 97.8 20 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
28c1bg6A_



not modelled 97.8 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:n-(1-d-carboxylethyl)-l-norvaline dehydrogenase;
PDBTitle: crystal structure of the n-(1-d-carboxylethyl)-l-norvaline2 dehydrogenase from arthrobacter sp. strain 1c
29c1bxgA_



not modelled 97.7 15 PDB header:amino acid dehydrogenase
Chain: A: PDB Molecule:phenylalanine dehydrogenase;
PDBTitle: phenylalanine dehydrogenase structure in ternary complex2 with nad+ and beta-phenylpropionate
30c2iz1C_



not modelled 97.7 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
31c2f1kD_



not modelled 97.7 17 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
32c3dhyC_



not modelled 97.7 18 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
33d1c1da1



not modelled 97.7 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
34c2p4qA_



not modelled 97.7 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating 1;
PDBTitle: crystal structure analysis of gnd1 in saccharomyces cerevisiae
35c2axqA_



not modelled 97.7 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
36c2rirA_



not modelled 97.7 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
37c1e5lA_



not modelled 97.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
38c3ggpA_



not modelled 97.7 9 PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+
39c3b1fA_



not modelled 97.7 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 mutans
40c1vpdA_



not modelled 97.7 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:tartronate semialdehyde reductase;
PDBTitle: x-ray crystal structure of tartronate semialdehyde reductase2 [salmonella typhimurium lt2]
41d1bg6a2



not modelled 97.7 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
42c3d4oA_



not modelled 97.6 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
43c2g5cD_



not modelled 97.6 9 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
44c3triB_



not modelled 97.6 17 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii
45c3oneA_



not modelled 97.6 25 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
46c3n58D_



not modelled 97.6 26 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
47c1pgqA_



not modelled 97.6 11 PDB header:oxidoreductase (choh(d)-nadp+(a))
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: crystallographic study of coenzyme, coenzyme analogue and substrate2 binding in 6-phosphogluconate dehydrogenase: implications for nadp3 specificity and the enzyme mechanism
48d1leha1



not modelled 97.6 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Aminoacid dehydrogenase-like, C-terminal domain
49c2vhyB_



not modelled 97.6 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of apo l-alanine dehydrogenase from2 mycobacterium tuberculosis
50d1pgja2



not modelled 97.5 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
51c3d1lB_



not modelled 97.5 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative nadp oxidoreductase bf3122;
PDBTitle: crystal structure of putative nadp oxidoreductase bf3122 from2 bacteroides fragilis
52c2y0dB_



not modelled 97.5 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: bcec mutation y10k
53c2qx7A_



not modelled 97.5 13 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
54c3gg2B_



not modelled 97.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:sugar dehydrogenase, udp-glucose/gdp-mannose
PDBTitle: crystal structure of udp-glucose 6-dehydrogenase from2 porphyromonas gingivalis bound to product udp-glucuronate
55c1lehB_



not modelled 97.5 10 PDB header:oxidoreductase
Chain: B: PDB Molecule:leucine dehydrogenase;
PDBTitle: leucine dehydrogenase from bacillus sphaericus
56c3ckyA_



not modelled 97.5 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-hydroxymethyl glutarate dehydrogenase;
PDBTitle: structural and kinetic properties of a beta-hydroxyacid dehydrogenase2 involved in nicotinate fermentation
57c3plnA_



not modelled 97.5 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: crystal structure of klebsiella pneumoniae udp-glucose 6-dehydrogenase2 complexed with udp-glucose
58c3qhaB_



not modelled 97.5 20 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase from mycobacterium2 avium 104
59c3k96B_



not modelled 97.5 14 PDB header:oxidoreductase
Chain: B: PDB Molecule:glycerol-3-phosphate dehydrogenase [nad(p)+];
PDBTitle: 2.1 angstrom resolution crystal structure of glycerol-3-phosphate2 dehydrogenase (gpsa) from coxiella burnetii
60c3hwrA_



not modelled 97.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of pane/apba family ketopantoate reductase2 (yp_299159.1) from ralstonia eutropha jmp134 at 2.15 a resolution
61c3g0oA_



not modelled 97.4 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of 3-hydroxyisobutyrate dehydrogenase2 (ygbj) from salmonella typhimurium
62c1mv8A_



not modelled 97.4 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:gdp-mannose 6-dehydrogenase;
PDBTitle: 1.55 a crystal structure of a ternary complex of gdp-mannose2 dehydrogenase from psuedomonas aeruginosa
63c1v8bA_



not modelled 97.4 15 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
64c3ojlA_



not modelled 97.4 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:cap5o;
PDBTitle: native structure of the udp-n-acetyl-mannosamine dehydrogenase cap5o2 from staphylococcus aureus
65c2ew2B_



not modelled 97.4 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:2-dehydropantoate 2-reductase, putative;
PDBTitle: crystal structure of the putative 2-dehydropantoate 2-reductase from2 enterococcus faecalis
66d2jfga1



not modelled 97.4 14 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
67c3gvpB_



not modelled 97.4 15 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
68c3pefA_



not modelled 97.4 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase, nad-binding;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter metallireducens in complex with nadp+
69c3c24A_



not modelled 97.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative oxidoreductase;
PDBTitle: crystal structure of a putative oxidoreductase (yp_511008.1) from2 jannaschia sp. ccs1 at 1.62 a resolution
70c2pv7B_



not modelled 97.3 17 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
71d3cuma2



not modelled 97.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
72c2gf2B_



not modelled 97.3 15 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
73d1xgka_



not modelled 97.3 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
74c2o3jC_



not modelled 97.3 15 PDB header:oxidoreductase
Chain: C: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of caenorhabditis elegans udp-glucose dehydrogenase
75d1li4a1



not modelled 97.3 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
76c1d4fD_



not modelled 97.3 23 PDB header:hydrolase
Chain: D: PDB Molecule:s-adenosylhomocysteine hydrolase;
PDBTitle: crystal structure of recombinant rat-liver d244e mutant s-2 adenosylhomocysteine hydrolase
77c2we7A_



not modelled 97.3 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:xanthine dehydrogenase;
PDBTitle: crystal structure of mycobacterium tuberculosis rv0376c2 homologue from mycobacterium smegmatis
78c3d64A_



not modelled 97.3 25 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
79d1l7da1



not modelled 97.3 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
80c1dliA_



not modelled 97.3 21 PDB header:oxidoreductase
Chain: A: PDB Molecule:udp-glucose dehydrogenase;
PDBTitle: the first structure of udp-glucose dehydrogenase (udpgdh) reveals the2 catalytic residues necessary for the two-fold oxidation
81c2ahrB_



not modelled 97.3 8 PDB header:oxidoreductase
Chain: B: PDB Molecule:putative pyrroline carboxylate reductase;
PDBTitle: crystal structures of 1-pyrroline-5-carboxylate reductase from human2 pathogen streptococcus pyogenes
82d1uxja1



not modelled 97.3 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:LDH N-terminal domain-like
83c2ag8A_



not modelled 97.3 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: nadp complex of pyrroline-5-carboxylate reductase from neisseria2 meningitidis
84d1np3a2



not modelled 97.2 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
85d1qyda_



not modelled 97.2 22 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
86c1np3B_



not modelled 97.2 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
87c2dwcB_



not modelled 97.2 16 PDB header:transferase
Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl
PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp
88c1i36A_



not modelled 97.2 10 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:conserved hypothetical protein mth1747;
PDBTitle: structure of conserved protein mth1747 of unknown function2 reveals structural similarity with 3-hydroxyacid3 dehydrogenases
89c2z2vA_



not modelled 97.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:hypothetical protein ph1688;
PDBTitle: crystal structure of l-lysine dehydrogenase from2 hyperthermophilic archaeon pyrococcus horikoshii
90c3e18A_



not modelled 97.2 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase;
PDBTitle: crystal structure of nad-binding protein from listeria innocua
91d1p3da1



not modelled 97.2 20 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
92c3dttA_



not modelled 97.1 16 PDB header:oxidoreductase
Chain: A: PDB Molecule:nadp oxidoreductase;
PDBTitle: crystal structure of a putative f420 dependent nadp-reductase2 (arth_0613) from arthrobacter sp. fb24 at 1.70 a resolution
93c2cvzD_



not modelled 97.1 12 PDB header:oxidoreductase
Chain: D: PDB Molecule:3-hydroxyisobutyrate dehydrogenase;
PDBTitle: structure of hydroxyisobutyrate dehydrogenase from thermus2 thermophilus hb8
94d1vpda2



not modelled 97.1 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
95c2ep9A_



not modelled 97.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:l-gulonate 3-dehydrogenase;
PDBTitle: crystal structure of the rabbit l-gulonate 3-dehydrogenase2 (nadh form)
96d2cvza2



not modelled 97.1 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
97d1v8ba1



not modelled 97.1 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
98d1dlja2



not modelled 97.1 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
99c2zcuA_



not modelled 97.1 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
100c3dzbA_



not modelled 97.1 17 PDB header:biosynthetic protein
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from streptococcus2 thermophilus
101c2hjrK_



not modelled 97.1 15 PDB header:oxidoreductase
Chain: K: PDB Molecule:malate dehydrogenase;
PDBTitle: crystal structure of cryptosporidium parvum malate2 dehydrogenase
102c2uyyD_



not modelled 97.1 16 PDB header:cytokine
Chain: D: PDB Molecule:n-pac protein;
PDBTitle: structure of the cytokine-like nuclear factor n-pac
103c3ezyB_



not modelled 97.1 12 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:dehydrogenase;
PDBTitle: crystal structure of probable dehydrogenase tm_0414 from2 thermotoga maritima
104c2q3eH_



not modelled 97.1 18 PDB header:oxidoreductase
Chain: H: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: structure of human udp-glucose dehydrogenase complexed with nadh and2 udp-glucose
105c3prjB_



not modelled 97.1 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:udp-glucose 6-dehydrogenase;
PDBTitle: role of packing defects in the evolution of allostery and induced fit2 in human udp-glucose dehydrogenase.
106c1kjjA_



not modelled 97.1 13 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s
107c3i5mA_



not modelled 97.1 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
108c3euwB_



not modelled 97.0 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:myo-inositol dehydrogenase;
PDBTitle: crystal structure of a myo-inositol dehydrogenase from corynebacterium2 glutamicum atcc 13032
109c2vrcD_



not modelled 97.0 20 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
110c2wtbA_



not modelled 97.0 12 PDB header:oxidoreductase
Chain: A: PDB Molecule:fatty acid multifunctional protein (atmfp2);
PDBTitle: arabidopsis thaliana multifuctional protein, mfp2
111c2g76A_



not modelled 97.0 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:d-3-phosphoglycerate dehydrogenase;
PDBTitle: crystal structure of human 3-phosphoglycerate dehydrogenase
112c3dojA_



not modelled 97.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:dehydrogenase-like protein;
PDBTitle: structure of glyoxylate reductase 1 from arabidopsis2 (atglyr1)
113c2eezG_



not modelled 97.0 9 PDB header:oxidoreductase
Chain: G: PDB Molecule:alanine dehydrogenase;
PDBTitle: crystal structure of alanine dehydrogenase from themus thermophilus
114c3pduF_



not modelled 97.0 12 PDB header:oxidoreductase
Chain: F: PDB Molecule:3-hydroxyisobutyrate dehydrogenase family protein;
PDBTitle: crystal structure of gamma-hydroxybutyrate dehydrogenase from2 geobacter sulfurreducens in complex with nadp+
115c3hn2A_



not modelled 97.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:2-dehydropantoate 2-reductase;
PDBTitle: crystal structure of 2-dehydropantoate 2-reductase from geobacter2 metallireducens gs-15
116c3ceaA_



not modelled 97.0 17 PDB header:oxidoreductase
Chain: A: PDB Molecule:myo-inositol 2-dehydrogenase;
PDBTitle: crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from2 lactobacillus plantarum at 2.40 a resolution
117d2pv7a2



not modelled 97.0 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
118d1mv8a2



not modelled 97.0 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
119d2ahra2



not modelled 97.0 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
120c1m75B_



not modelled 97.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:3-hydroxyacyl-coa dehydrogenase;
PDBTitle: crystal structure of the n208s mutant of l-3-hydroxyacyl-2 coa dehydrogenase in complex with nad and acetoacetyl-coa

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0