Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP00959
DateThu Jan 5 10:57:21 GMT 2012
Unique Job ID590fc0eec7767e03

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1rqgA_
Top template information
PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: methionyl-trna synthetase from pyrococcus abyssi
Confidence and coverage
Confidence:100.0% Coverage: 86%
585 residues ( 86% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
658 residues ( 97%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIM
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Disorder  ??????





















































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   .........70.........80.........90.........100.........110.........120
Sequence  LKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEENRQLSELIYSRLKENGFI
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   .........130.........140.........150.........160.........170.........180
Sequence  KNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCEVCGATYSPTELIEPKSVVSG
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   .........190.........200.........210.........220.........230.........240
Sequence  ATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFG
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   .........250.........260.........270.........280.........290.........300
Sequence  FEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVY
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??

?
























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   .........310.........320.........330.........340.........350.........360
Sequence  FHSLFWPAMLEGSNFRKPSNLFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYY
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?




















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   .........370.........380.........390.........400.........410.........420
Sequence  TAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFDGVLASELADPQLYK
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?????






































??









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   .........430.........440.........450.........460.........470.........480
Sequence  TFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSM
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   .........490.........500.........510.........520.........530.........540
Sequence  GINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMRQV
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   .........550.........560.........570.........580.........590.........600
Sequence  EALVEASKEEVKAAAAPVTGPLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLR
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Disorder 




?
?????????????????
?






?
???





















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   .........610.........620.........630.........640.........650.........660
Sequence  LTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKD
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?















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   .........670.......
Sequence  IFLLSPDAGAKPGHQVK
Secondary structure 











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Disorder 






?

???????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1rqg chain A

3D model

Region: 4 - 622
Aligned: 585
Modelled: 589
Confidence: 100.0%
Identity: 33%
PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: methionyl-trna synthetase from pyrococcus abyssi

Phyre2

PDB 1pfu chain A

3D model

Region: 5 - 551
Aligned: 547
Modelled: 547
Confidence: 100.0%
Identity: 100%
PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate

Phyre2

PDB 3kfl chain A

3D model

Region: 5 - 536
Aligned: 509
Modelled: 512
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate

Phyre2

PDB 1gax chain B

3D model

Region: 3 - 601
Aligned: 574
Modelled: 599
Confidence: 100.0%
Identity: 21%
PDB header:ligase/rna
Chain: B: PDB Molecule:valyl-trna synthetase;
PDBTitle: crystal structure of thermus thermophilus valyl-trna2 synthetase complexed with trna(val) and valyl-adenylate3 analogue

Phyre2

PDB 1woy chain A

3D model

Region: 4 - 534
Aligned: 488
Modelled: 501
Confidence: 100.0%
Identity: 24%
PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus

Phyre2

PDB 1qu2 chain A

3D model

Region: 5 - 595
Aligned: 571
Modelled: 575
Confidence: 100.0%
Identity: 20%
PDB header:ligase/rna
Chain: A: PDB Molecule:isoleucyl-trna synthetase;
PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin

Phyre2

PDB 1ile chain A

3D model

Region: 5 - 558
Aligned: 541
Modelled: 554
Confidence: 100.0%
Identity: 23%
PDB header:aminoacyl-trna synthetase
Chain: A: PDB Molecule:isoleucyl-trna synthetase;
PDBTitle: isoleucyl-trna synthetase

Phyre2

PDB 1wz2 chain B

3D model

Region: 2 - 670
Aligned: 636
Modelled: 669
Confidence: 100.0%
Identity: 19%
PDB header:ligase/rna
Chain: B: PDB Molecule:leucyl-trna synthetase;
PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex

Phyre2

PDB 2ct8 chain A

3D model

Region: 1 - 536
Aligned: 458
Modelled: 471
Confidence: 100.0%
Identity: 28%
PDB header:ligase/rna
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue

Phyre2

PDB 2x1l chain C

3D model

Region: 5 - 536
Aligned: 463
Modelled: 471
Confidence: 100.0%
Identity: 27%
PDB header:ligase
Chain: C: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine

Phyre2

PDB 1wkb chain A

3D model

Region: 5 - 508
Aligned: 482
Modelled: 496
Confidence: 100.0%
Identity: 22%
PDB header:ligase
Chain: A: PDB Molecule:leucyl-trna synthetase;
PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation

Phyre2

PDB 1obh chain A

3D model

Region: 3 - 525
Aligned: 488
Modelled: 499
Confidence: 100.0%
Identity: 24%
PDB header:synthetase
Chain: A: PDB Molecule:leucyl-trna synthetase;
PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site

Phyre2

PDB 1h3n chain A domain 3

3D model

Region: 2 - 381
Aligned: 344
Modelled: 352
Confidence: 100.0%
Identity: 24%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1ffy chain A domain 3

3D model

Region: 2 - 383
Aligned: 336
Modelled: 348
Confidence: 100.0%
Identity: 23%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1pfv chain A domain 2

3D model

Region: 5 - 389
Aligned: 350
Modelled: 350
Confidence: 100.0%
Identity: 99%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1ile chain A domain 3

3D model

Region: 2 - 383
Aligned: 345
Modelled: 355
Confidence: 100.0%
Identity: 23%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1rqg chain A domain 2

3D model

Region: 4 - 386
Aligned: 345
Modelled: 347
Confidence: 100.0%
Identity: 35%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1ivs chain A domain 4

3D model

Region: 3 - 383
Aligned: 339
Modelled: 350
Confidence: 100.0%
Identity: 23%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 2d5b chain A domain 2

3D model

Region: 4 - 385
Aligned: 342
Modelled: 352
Confidence: 100.0%
Identity: 26%
Fold: Adenine nucleotide alpha hydrolase-like
Superfamily: Nucleotidylyl transferase
Family: Class I aminoacyl-tRNA synthetases (RS), catalytic domain

Phyre2

PDB 1u0b chain B

3D model

Region: 2 - 575
Aligned: 432
Modelled: 456
Confidence: 100.0%
Identity: 21%
PDB header:ligase/rna
Chain: B: PDB Molecule:cysteinyl trna;
PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys

Phyre2
1

c1rqgA_
2

c1pfuA_
3

c3kflA_
4

c1gaxB_
5

c1woyA_
6

c1qu2A_
7

c1ileA_
8

c1wz2B_
9

c2ct8A_
10

c2x1lC_
11

c1wkbA_
12

c1obhA_
13

d1h3na3
14

d1ffya3
15

d1pfva2
16

d1ilea3
17

d1rqga2
18

d1ivsa4
19

d2d5ba2
20

c1u0bB_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1rqgA_



100.0 33 PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: methionyl-trna synthetase from pyrococcus abyssi
2c1pfuA_



100.0 100 PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: methionyl-trna synthetase from escherichia coli complexed2 with methionine phosphinate
3c3kflA_



100.0 24 PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: leishmania major methionyl-trna synthetase in complex with2 methionyladenylate and pyrophosphate
4c1gaxB_



100.0 21 PDB header:ligase/rna
Chain: B: PDB Molecule:valyl-trna synthetase;
PDBTitle: crystal structure of thermus thermophilus valyl-trna2 synthetase complexed with trna(val) and valyl-adenylate3 analogue
5c1woyA_



100.0 24 PDB header:ligase
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of methionyl trna synthetase y225f mutant2 from thermus thermophilus
6c1qu2A_



100.0 20 PDB header:ligase/rna
Chain: A: PDB Molecule:isoleucyl-trna synthetase;
PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin
7c1ileA_



100.0 23 PDB header:aminoacyl-trna synthetase
Chain: A: PDB Molecule:isoleucyl-trna synthetase;
PDBTitle: isoleucyl-trna synthetase
8c1wz2B_



100.0 19 PDB header:ligase/rna
Chain: B: PDB Molecule:leucyl-trna synthetase;
PDBTitle: the crystal structure of leucyl-trna synthetase and trna(leucine)2 complex
9c2ct8A_



100.0 28 PDB header:ligase/rna
Chain: A: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of aquifex aeolicus methionyl-trna2 synthetase complexed with trna(met) and methionyl-adenylate3 anologue
10c2x1lC_



100.0 27 PDB header:ligase
Chain: C: PDB Molecule:methionyl-trna synthetase;
PDBTitle: crystal structure of mycobacterium smegmatis methionyl-trna2 synthetase in complex with methionine and adenosine
11c1wkbA_



100.0 22 PDB header:ligase
Chain: A: PDB Molecule:leucyl-trna synthetase;
PDBTitle: crystal structure of leucyl-trna synthetase from the2 archaeon pyrococcus horikoshii reveals a novel editing3 domain orientation
12c1obhA_



100.0 24 PDB header:synthetase
Chain: A: PDB Molecule:leucyl-trna synthetase;
PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
13d1h3na3



100.0 24 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
14d1ffya3



100.0 23 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
15d1pfva2



100.0 99 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
16d1ilea3



100.0 23 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
17d1rqga2



100.0 35 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
18d1ivsa4



100.0 23 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
19d2d5ba2



100.0 26 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
20c1u0bB_



100.0 21 PDB header:ligase/rna
Chain: B: PDB Molecule:cysteinyl trna;
PDBTitle: crystal structure of cysteinyl-trna synthetase binary2 complex with trnacys
21c3c8zB_



not modelled 100.0 17 PDB header:ligase
Chain: B: PDB Molecule:cysteinyl-trna synthetase;
PDBTitle: the 1.6 a crystal structure of mshc: the rate limiting2 enzyme in the mycothiol biosynthetic pathway
22c3tqoA_



not modelled 100.0 19 PDB header:ligase
Chain: A: PDB Molecule:cysteinyl-trna synthetase;
PDBTitle: structure of the cysteinyl-trna synthetase (cyss) from coxiella2 burnetii.
23c3sp1B_



not modelled 100.0 15 PDB header:ligase
Chain: B: PDB Molecule:cysteinyl-trna synthetase;
PDBTitle: crystal structure of cysteinyl-trna synthetase (cyss) from borrelia2 burgdorferi
24c3fnrA_



not modelled 100.0 16 PDB header:transferase
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: crystal structure of putative arginyl t-rna synthetase from2 campylobacter jejuni;
25c1iq0A_



not modelled 100.0 15 PDB header:ligase
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: thermus thermophilus arginyl-trna synthetase
26d1li5a2



not modelled 100.0 21 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
27c2zufA_



not modelled 100.0 17 PDB header:ligase/rna
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: crystal structure of pyrococcus horikoshii arginyl-trna2 synthetase complexed with trna(arg)
28d1iq0a2



not modelled 100.0 12 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
29c1f7uA_



not modelled 100.0 21 PDB header:ligase/rna
Chain: A: PDB Molecule:arginyl-trna synthetase;
PDBTitle: crystal structure of the arginyl-trna synthetase complexed with the2 trna(arg) and l-arg
30d1f7ua2



not modelled 100.0 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
31d1irxa2



not modelled 100.0 16 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
32d1ntga_



not modelled 100.0 32 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
33d1fl0a_



not modelled 100.0 34 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
34d1pfva1



not modelled 100.0 100 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
35d1gd7a_



not modelled 100.0 29 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
36c2q2iA_



not modelled 99.9 27 PDB header:chaperone
Chain: A: PDB Molecule:secretion chaperone;
PDBTitle: crystal structure of the protein secretion chaperone csaa from2 agrobacterium tumefaciens.
37d1rqga1



not modelled 99.9 26 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
38d1mkha_



not modelled 99.9 41 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
39d1pyba_



not modelled 99.9 48 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
40d1pxfa_



not modelled 99.9 29 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
41c2cwpA_



not modelled 99.9 31 PDB header:ligase
Chain: A: PDB Molecule:metrs related protein;
PDBTitle: crystal structure of metrs related protein from pyrococcus horikoshii
42c2nzoD_



not modelled 99.9 32 PDB header:chaperone
Chain: D: PDB Molecule:protein csaa;
PDBTitle: crystal structure of a secretion chaperone csaa from bacillus subtilis2 in the space group p 32 2 1
43c2e8gB_



not modelled 99.9 17 PDB header:rna binding protein
Chain: B: PDB Molecule:hypothetical protein ph0536;
PDBTitle: the structure of protein from p. horikoshii at 1.7 angstrom2 resolution
44d2d5ba1



not modelled 99.9 20 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
45c1g59A_



not modelled 99.8 18 PDB header:ligase/rna
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: glutamyl-trna synthetase complexed with trna(glu).
46c1irxA_



not modelled 99.8 16 PDB header:ligase
Chain: A: PDB Molecule:lysyl-trna synthetase;
PDBTitle: crystal structure of class i lysyl-trna synthetase
47c3afhA_



not modelled 99.8 16 PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase 2;
PDBTitle: crystal structure of thermotoga maritima nondiscriminating glutamyl-2 trna synthetase in complex with a glutamyl-amp analog
48c2ja2A_



not modelled 99.8 15 PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: mycobacterium tuberculosis glutamyl-trna synthetase
49c2cfoA_



not modelled 99.8 18 PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: non-discriminating glutamyl-trna synthetase from2 thermosynechococcus elongatus in complex with glu
50c2o5rA_



not modelled 99.8 16 PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase 1;
PDBTitle: crystal structure of glutamyl-trna synthetase 1 (ec 6.1.1.17)2 (glutamate-trna ligase 1) (glurs 1) (tm1351) from thermotoga maritima3 at 2.5 a resolution
51d1gtra2



not modelled 99.7 12 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
52d1ivsa2



not modelled 99.7 17 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
53d1qu3a1



not modelled 99.6 13 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
54d1ilea1



not modelled 99.6 17 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
55d1ffya1



not modelled 99.6 13 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
56d1jjcb3



not modelled 99.6 28 Fold:OB-fold
Superfamily:Nucleic acid-binding proteins
Family:Myf domain
57c3bu2B_



not modelled 99.6 19 PDB header:rna binding protein
Chain: B: PDB Molecule:putative trna-binding protein;
PDBTitle: crystal structure of a trna-binding protein from2 staphylococcus saprophyticus subsp. saprophyticus.3 northeast structural genomics consortium target syr77
58c3al0C_



not modelled 99.5 17 PDB header:ligase/rna
Chain: C: PDB Molecule:glutamyl-trna(gln) amidotransferase subunit c, glutamyl-
PDBTitle: crystal structure of the glutamine transamidosome from thermotoga2 maritima in the glutamylation state.
59c1exdA_



not modelled 99.4 16 PDB header:ligase/rna
Chain: A: PDB Molecule:glutaminyl-trna synthetase;
PDBTitle: crystal structure of a tight-binding glutamine trna bound2 to glutamine aminoacyl trna synthetase
60c2hz7A_



not modelled 99.4 13 PDB header:ligase
Chain: A: PDB Molecule:glutaminyl-trna synthetase;
PDBTitle: crystal structure of the glutaminyl-trna synthetase from2 deinococcus radiodurans
61d1h3na1



not modelled 99.4 20 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
62d1j09a2



not modelled 99.2 18 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
63c3pcoD_



not modelled 99.2 21 PDB header:ligase
Chain: D: PDB Molecule:phenylalanyl-trna synthetase, beta chain;
PDBTitle: crystal structure of e. coli phenylalanine-trna synthetase complexed2 with phenylalanine and amp
64c3aiiA_



not modelled 99.0 16 PDB header:ligase
Chain: A: PDB Molecule:glutamyl-trna synthetase;
PDBTitle: archaeal non-discriminating glutamyl-trna synthetase from2 methanothermobacter thermautotrophicus
65c2akwB_



not modelled 99.0 29 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: crystal structure of t.thermophilus phenylalanyl-trna synthetase2 complexed with p-cl-phenylalanine
66d1nzja_



not modelled 98.6 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
67c2cybA_



not modelled 98.5 22 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with2 l-tyrosine from archaeoglobus fulgidus
68c3a05A_



not modelled 98.3 17 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 hyperthermophilic archaeon, aeropyrum pernix k1 complex3 with tryptophan
69c3hzrD_



not modelled 98.2 15 PDB header:ligase
Chain: D: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: tryptophanyl-trna synthetase homolog from entamoeba histolytica
70c3focB_



not modelled 98.2 13 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: tryptophanyl-trna synthetase from giardia lamblia
71c1h3eA_



not modelled 98.1 17 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: tyrosyl-trna synthetase from thermus thermophilus complexed2 with wild-type trnatyr(gua) and with atp and tyrosinol
72c2rhsB_



not modelled 98.0 27 PDB header:ligase
Chain: B: PDB Molecule:phenylalanyl-trna synthetase beta chain;
PDBTitle: phers from staphylococcus haemolyticus- rational protein2 engineering and inhibitor studies
73c2quiB_



not modelled 98.0 15 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structures of human tryptophanyl-trna synthetase in2 complex with tryptophanamide and atp
74d1pfva3



not modelled 97.9 100 Fold:Rubredoxin-like
Superfamily:Methionyl-tRNA synthetase (MetRS), Zn-domain
Family:Methionyl-tRNA synthetase (MetRS), Zn-domain
75d1r6ta2



not modelled 97.8 13 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
76d1iq0a1



not modelled 97.6 18 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
77d1f7ua1



not modelled 97.4 19 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
78c3jxeB_



not modelled 97.2 14 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of pyrococcus horikoshii tryptophanyl-trna2 synthetase in complex with trpamp
79c2g36A_



not modelled 97.0 14 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase (ec 6.1.1.2)2 (tryptophan-trna ligase)(trprs) (tm0492) from thermotoga maritima at3 2.50 a resolution
80d1h3fa1



not modelled 97.0 18 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
81c3hv0A_



not modelled 96.8 12 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: tryptophanyl-trna synthetase from cryptosporidium parvum
82d1j1ua_



not modelled 96.6 16 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
83c2dlcX_



not modelled 96.5 11 PDB header:ligase/trna
Chain: X: PDB Molecule:tyrosyl-trna synthetase, cytoplasmic;
PDBTitle: crystal structure of the ternary complex of yeast tyrosyl-trna2 synthetase
84d1n3la_



not modelled 96.4 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
85c2ip1A_



not modelled 96.3 17 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure analysis of s. cerevisiae tryptophanyl trna2 synthetase
86c2j5bA_



not modelled 96.3 15 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: structure of the tyrosyl trna synthetase from acanthamoeba2 polyphaga mimivirus complexed with tyrosynol
87c2janD_



not modelled 96.2 16 PDB header:ligase
Chain: D: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: tyrosyl-trna synthetase from mycobacterium tuberculosis in2 unliganded state
88c2el7A_



not modelled 96.1 22 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from thermus2 thermophilus
89d1i6la_



not modelled 96.1 14 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
90c3m5wB_



not modelled 96.1 18 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from2 campylobacter jejuni
91c1jiiA_



not modelled 96.0 15 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of s. aureus tyrrs in complex with sb-219383
92c3prhB_



not modelled 96.0 13 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: tryptophanyl-trna synthetase val144pro mutant from b. subtilis
93c3i05B_



not modelled 95.9 12 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: tryptophanyl-trna synthetase from trypanosoma brucei
94c1q11A_



not modelled 95.9 16 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of an active fragment of human tyrosyl-trna2 synthetase with tyrosinol
95c1yi8C_



not modelled 95.9 14 PDB header:ligase
Chain: C: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl trrna synthetase ii from deinococcus2 radiodurans in complex with l-trp
96c1r6uB_



not modelled 95.8 16 PDB header:ligase
Chain: B: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of an active fragment of human tryptophanyl-trna2 synthetase with cytokine activity
97c2rkjM_



not modelled 95.7 14 PDB header:ligase/rna
Chain: M: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: cocrystal structure of a tyrosyl-trna synthetase splicing2 factor with a group i intron rna
98d1jila_



not modelled 95.7 15 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
99c3sz3A_



not modelled 95.7 16 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from vibrio cholerae2 with an endogenous tryptophan
100c2cyaA_



not modelled 95.6 10 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of tyrosyl-trna synthetase from aeropyrum pernix
101c1x8xA_



not modelled 95.4 15 PDB header:ligase
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: tyrosyl t-rna synthetase from e.coli complexed with tyrosine
102c3p0jD_



not modelled 95.4 17 PDB header:ligase
Chain: D: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: leishmania major tyrosyl-trna synthetase in complex with tyrosinol,2 triclinic crystal form 1
103c3n9iA_



not modelled 95.4 15 PDB header:ligase
Chain: A: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from yersinia pestis2 co92
104c2yy5C_



not modelled 95.2 13 PDB header:ligase
Chain: C: PDB Molecule:tryptophanyl-trna synthetase;
PDBTitle: crystal structure of tryptophanyl-trna synthetase from mycoplasma2 pneumoniae
105c2cycB_



not modelled 95.0 16 PDB header:ligase
Chain: B: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of tyrosyl-trna synthetase complexed with l-tyrosine2 from pyrococcus horikoshii
106c2pidB_



not modelled 94.1 15 PDB header:ligase
Chain: B: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: crystal structure of human mitochondrial tyrosyl-trna synthetase in2 complex with an adenylate analog
107d1u0bb1



not modelled 94.0 21 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
108d1li5a1



not modelled 91.9 24 Fold:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Superfamily:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
Family:Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
109d2ts1a_



not modelled 91.0 14 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Class I aminoacyl-tRNA synthetases (RS), catalytic domain
110c2ts1A_



not modelled 91.0 14 PDB header:ligase (synthetase)
Chain: A: PDB Molecule:tyrosyl-trna synthetase;
PDBTitle: structure of tyrosyl-t/rna synthetase refined at 2.3 angstroms2 resolution. interaction of the enzyme with the tyrosyl adenylate3 intermediate
111c2iyaB_



not modelled 87.3 26 PDB header:transferase
Chain: B: PDB Molecule:oleandomycin glycosyltransferase;
PDBTitle: the crystal structure of macrolide glycosyltransferases: a2 blueprint for antibiotic engineering
112d1f0ka_



not modelled 83.3 24 Fold:UDP-Glycosyltransferase/glycogen phosphorylase
Superfamily:UDP-Glycosyltransferase/glycogen phosphorylase
Family:Peptidoglycan biosynthesis glycosyltransferase MurG
113c1dvbA_



not modelled 71.4 15 PDB header:electron transport
Chain: A: PDB Molecule:rubrerythrin;
PDBTitle: rubrerythrin
114c3dzcA_



not modelled 69.0 16 PDB header:isomerase
Chain: A: PDB Molecule:udp-n-acetylglucosamine 2-epimerase;
PDBTitle: 2.35 angstrom resolution structure of wecb (vc0917), a udp-n-2 acetylglucosamine 2-epimerase from vibrio cholerae.
115c3cp0A_



not modelled 66.0 26 PDB header:membrane protein
Chain: A: PDB Molecule:membrane protein implicated in regulation of membrane
PDBTitle: crystal structure of the soluble domain of membrane protein implicated2 in regulation of membrane protease activity from corynebacterium3 glutamicum
116d1ccwa_



not modelled 65.6 18 Fold:Flavodoxin-like
Superfamily:Cobalamin (vitamin B12)-binding domain
Family:Cobalamin (vitamin B12)-binding domain
117c2hr5B_



not modelled 62.9 17 PDB header:metal binding protein
Chain: B: PDB Molecule:rubrerythrin;
PDBTitle: pf1283- rubrerythrin from pyrococcus furiosus iron bound form
118d1qmga2



not modelled 62.5 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
119c3f3mA_



not modelled 60.7 21 PDB header:transferase
Chain: A: PDB Molecule:phosphopantetheine adenylyltransferase;
PDBTitle: six crystal structures of two phosphopantetheine2 adenylyltransferases reveal an alternative ligand binding3 mode and an associated structural change
120d1od6a_



not modelled 58.5 10 Fold:Adenine nucleotide alpha hydrolase-like
Superfamily:Nucleotidylyl transferase
Family:Adenylyltransferase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0