Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP31069
DateWed Jan 25 15:20:48 GMT 2012
Unique Job ID56be85d3f8a1469f

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c1lnqC_
Top template information
PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a
Confidence and coverage
Confidence:100.0% Coverage: 44%
185 residues ( 44% of your sequence) have been modelled with 100.0% confidence by the single highest scoring template.
Additional confident templates have been detected (see Domain analysis) which cover other regions of your sequence.
391 residues ( 94%) could be modelled at >90% confidence using multiple-templates.
You may wish to try resubmitting your sequence in "intensive" mode to model more of your sequence.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLS
Secondary structure 




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Disorder  ????























































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   .........70.........80.........90.........100.........110.........120
Sequence  LLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFT
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   .........130.........140.........150.........160.........170.........180
Sequence  LVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYLSEGFNPRIESLMTAFYFSI
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   .........190.........200.........210.........220.........230.........240
Sequence  ETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTM
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???
??
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   .........250.........260.........270.........280.........290.........300
Sequence  HRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSND
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   .........310.........320.........330.........340.........350.........360
Sequence  SSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPD
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   .........370.........380.........390.........400.........410.......
Sequence  IILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSDNDELETKADSKESAQK
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????????????????????????
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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 1lnq chain C

3D model

Region: 171 - 380
Aligned: 185
Modelled: 191
Confidence: 100.0%
Identity: 25%
PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a

Phyre2

PDB 1id1 chain A

3D model

Region: 241 - 393
Aligned: 153
Modelled: 153
Confidence: 100.0%
Identity: 100%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 3fwz chain A

3D model

Region: 241 - 380
Aligned: 136
Modelled: 140
Confidence: 99.9%
Identity: 12%
PDB header:membrane protein
Chain: A: PDB Molecule:inner membrane protein ybal;
PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli

Phyre2

PDB 3eyw chain A

3D model

Region: 245 - 378
Aligned: 130
Modelled: 134
Confidence: 99.9%
Identity: 17%
PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff

Phyre2

PDB 2fy8 chain A domain 1

3D model

Region: 244 - 377
Aligned: 128
Modelled: 134
Confidence: 99.9%
Identity: 23%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 1lss chain A

3D model

Region: 245 - 379
Aligned: 131
Modelled: 135
Confidence: 99.9%
Identity: 21%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 2g1u chain A

3D model

Region: 240 - 379
Aligned: 136
Modelled: 139
Confidence: 99.9%
Identity: 15%
PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution

Phyre2

PDB 2fy8 chain A

3D model

Region: 243 - 380
Aligned: 132
Modelled: 138
Confidence: 99.9%
Identity: 23%
PDB header:transport protein
Chain: A: PDB Molecule:calcium-gated potassium channel mthk;
PDBTitle: crystal structure of mthk rck domain in its ligand-free gating-ring2 form

Phyre2

PDB 3llv chain A

3D model

Region: 243 - 378
Aligned: 131
Modelled: 136
Confidence: 99.8%
Identity: 16%
PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a

Phyre2

PDB 3c85 chain A

3D model

Region: 241 - 380
Aligned: 137
Modelled: 140
Confidence: 99.8%
Identity: 12%
PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus

Phyre2

PDB 2hmv chain A domain 1

3D model

Region: 244 - 381
Aligned: 134
Modelled: 138
Confidence: 99.8%
Identity: 12%
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Family: Potassium channel NAD-binding domain

Phyre2

PDB 3l4b chain G

3D model

Region: 245 - 381
Aligned: 134
Modelled: 137
Confidence: 99.8%
Identity: 19%
PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima

Phyre2

PDB 3u6n chain C

3D model

Region: 244 - 406
Aligned: 161
Modelled: 163
Confidence: 99.8%
Identity: 18%
PDB header:transport protein
Chain: C: PDB Molecule:high-conductance ca2+-activated k+ channel protein;
PDBTitle: open structure of the bk channel gating ring

Phyre2

PDB 3mt5 chain A

3D model

Region: 244 - 384
Aligned: 141
Modelled: 141
Confidence: 99.7%
Identity: 20%
PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:potassium large conductance calcium-activated channel,
PDBTitle: crystal structure of the human bk gating apparatus

Phyre2

PDB 3naf chain A

3D model

Region: 234 - 405
Aligned: 170
Modelled: 172
Confidence: 99.7%
Identity: 18%
PDB header:ion transport
Chain: A: PDB Molecule:calcium-activated potassium channel subunit alpha-1;
PDBTitle: structure of the intracellular gating ring from the human high-2 conductance ca2+ gated k+ channel (bk channel)

Phyre2

PDB 2r9r chain H

3D model

Region: 3 - 231
Aligned: 229
Modelled: 229
Confidence: 99.6%
Identity: 13%
PDB header:membrane protein, transport protein
Chain: H: PDB Molecule:paddle chimera voltage gated potassium channel kv1.2-kv2.1;
PDBTitle: shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle2 chimera channel) in association with beta subunit

Phyre2

PDB 3beh chain A

3D model

Region: 28 - 238
Aligned: 211
Modelled: 211
Confidence: 99.5%
Identity: 12%
PDB header:membrane protein
Chain: A: PDB Molecule:mll3241 protein;
PDBTitle: structure of a bacterial cyclic nucleotide regulated ion channel

Phyre2

PDB 1f6g chain A

3D model

Region: 113 - 241
Aligned: 128
Modelled: 129
Confidence: 99.4%
Identity: 24%
Fold: Voltage-gated potassium channels
Superfamily: Voltage-gated potassium channels
Family: Voltage-gated potassium channels

Phyre2

PDB 1orq chain C

3D model

Region: 18 - 226
Aligned: 209
Modelled: 209
Confidence: 99.3%
Identity: 14%
Fold: Voltage-gated potassium channels
Superfamily: Voltage-gated potassium channels
Family: Voltage-gated potassium channels

Phyre2

PDB 1r3j chain C

3D model

Region: 138 - 234
Aligned: 97
Modelled: 97
Confidence: 99.2%
Identity: 24%
Fold: Voltage-gated potassium channels
Superfamily: Voltage-gated potassium channels
Family: Voltage-gated potassium channels

Phyre2
1

c1lnqC_
2

d1id1a_
3

c3fwzA_
4

c3eywA_
5

d2fy8a1
6

d1lssa_
7

c2g1uA_
8

c2fy8A_
9

c3llvA_
10

c3c85A_
11

d2hmva1
12

c3l4bG_
13

c3u6nC_
14

c3mt5A_
15

c3nafA_
16

c2r9rH_
17

c3behA_
18

d1f6ga_
19

d1orqc_
20

d1r3jc_
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Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c1lnqC_



100.0 25 PDB header:metal transport
Chain: C: PDB Molecule:potassium channel related protein;
PDBTitle: crystal structure of mthk at 3.3 a
2d1id1a_



100.0 100 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
3c3fwzA_



99.9 12 PDB header:membrane protein
Chain: A: PDB Molecule:inner membrane protein ybal;
PDBTitle: crystal structure of trka-n domain of inner membrane protein ybal from2 escherichia coli
4c3eywA_



99.9 17 PDB header:transport protein
Chain: A: PDB Molecule:c-terminal domain of glutathione-regulated potassium-efflux
PDBTitle: crystal structure of the c-terminal domain of e. coli kefc in complex2 with keff
5d2fy8a1



99.9 23 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
6d1lssa_



99.9 21 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
7c2g1uA_



99.9 15 PDB header:transport protein
Chain: A: PDB Molecule:hypothetical protein tm1088a;
PDBTitle: crystal structure of a putative transport protein (tm1088a) from2 thermotoga maritima at 1.50 a resolution
8c2fy8A_



99.9 23 PDB header:transport protein
Chain: A: PDB Molecule:calcium-gated potassium channel mthk;
PDBTitle: crystal structure of mthk rck domain in its ligand-free gating-ring2 form
9c3llvA_



99.8 16 PDB header:nad(p) binding protein
Chain: A: PDB Molecule:exopolyphosphatase-related protein;
PDBTitle: the crystal structure of the nad(p)-binding domain of an2 exopolyphosphatase-related protein from archaeoglobus fulgidus to3 1.7a
10c3c85A_



99.8 12 PDB header:transport protein
Chain: A: PDB Molecule:putative glutathione-regulated potassium-efflux system
PDBTitle: crystal structure of trka domain of putative glutathione-regulated2 potassium-efflux kefb from vibrio parahaemolyticus
11d2hmva1



99.8 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Potassium channel NAD-binding domain
12c3l4bG_



99.8 19 PDB header:transport protein
Chain: G: PDB Molecule:trka k+ channel protien tm1088b;
PDBTitle: crystal structure of an octomeric two-subunit trka k+ channel ring2 gating assembly, tm1088a:tm1088b, from thermotoga maritima
13c3u6nC_



99.8 18 PDB header:transport protein
Chain: C: PDB Molecule:high-conductance ca2+-activated k+ channel protein;
PDBTitle: open structure of the bk channel gating ring
14c3mt5A_



99.7 20 PDB header:membrane protein, transport protein
Chain: A: PDB Molecule:potassium large conductance calcium-activated channel,
PDBTitle: crystal structure of the human bk gating apparatus
15c3nafA_



99.7 18 PDB header:ion transport
Chain: A: PDB Molecule:calcium-activated potassium channel subunit alpha-1;
PDBTitle: structure of the intracellular gating ring from the human high-2 conductance ca2+ gated k+ channel (bk channel)
16c2r9rH_



99.6 13 PDB header:membrane protein, transport protein
Chain: H: PDB Molecule:paddle chimera voltage gated potassium channel kv1.2-kv2.1;
PDBTitle: shaker family voltage dependent potassium channel (kv1.2-kv2.1 paddle2 chimera channel) in association with beta subunit
17c3behA_



99.5 12 PDB header:membrane protein
Chain: A: PDB Molecule:mll3241 protein;
PDBTitle: structure of a bacterial cyclic nucleotide regulated ion channel
18d1f6ga_



99.4 24 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
19d1orqc_



99.3 14 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
20d1r3jc_



99.2 24 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
21c2kb1A_



not modelled 99.2 28 PDB header:membrane protein
Chain: A: PDB Molecule:wsk3;
PDBTitle: nmr studies of a channel protein without membrane:2 structure and dynamics of water-solubilized kcsa
22d2a9ha1



not modelled 99.1 24 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
23c3e8gB_



not modelled 99.1 20 PDB header:membrane protein
Chain: B: PDB Molecule:potassium channel protein;
PDBTitle: crystal structure of the the open nak channel-na+/ca2+ complex
24c3ifxB_



not modelled 99.0 26 PDB header:membrane protein
Chain: B: PDB Molecule:voltage-gated potassium channel;
PDBTitle: crystal structure of the spin-labeled kcsa mutant v48r1
25c2qksA_



not modelled 99.0 22 PDB header:metal transport
Chain: A: PDB Molecule:kir3.1-prokaryotic kir channel chimera;
PDBTitle: crystal structure of a kir3.1-prokaryotic kir channel chimera
26c1xl6B_



not modelled 99.0 23 PDB header:metal transport
Chain: B: PDB Molecule:inward rectifier potassium channel;
PDBTitle: intermediate gating structure 2 of the inwardly rectifying k+ channel2 kirbac3.1
27d1xl4a2



not modelled 99.0 23 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
28d1p7ba2



not modelled 98.8 24 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
29c1p7bB_



not modelled 98.6 23 PDB header:metal transport
Chain: B: PDB Molecule:integral membrane channel and cytosolic domains;
PDBTitle: crystal structure of an inward rectifier potassium channel
30c3jycA_



not modelled 98.4 20 PDB header:metal transport
Chain: A: PDB Molecule:inward-rectifier k+ channel kir2.2;
PDBTitle: crystal structure of the eukaryotic strong inward-rectifier2 k+ channel kir2.2 at 3.1 angstrom resolution
31d1e5qa1



not modelled 98.3 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain
32d1pjqa1



not modelled 98.3 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
33d1lnqa2



not modelled 98.3 33 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
34c2qx7A_



not modelled 97.9 10 PDB header:plant protein
Chain: A: PDB Molecule:eugenol synthase 1;
PDBTitle: structure of eugenol synthase from ocimum basilicum
35d2h8pc1



not modelled 97.7 22 Fold:Voltage-gated potassium channels
Superfamily:Voltage-gated potassium channels
Family:Voltage-gated potassium channels
36d1xgka_



not modelled 97.4 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
37c3ic5A_



not modelled 97.4 16 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:putative saccharopine dehydrogenase;
PDBTitle: n-terminal domain of putative saccharopine dehydrogenase from ruegeria2 pomeroyi.
38c2we7A_



not modelled 97.2 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:xanthine dehydrogenase;
PDBTitle: crystal structure of mycobacterium tuberculosis rv0376c2 homologue from mycobacterium smegmatis
39d2pgda2



not modelled 97.1 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
40d1kyqa1



not modelled 97.0 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Siroheme synthase N-terminal domain-like
41c3ktdC_



not modelled 97.0 10 PDB header:oxidoreductase
Chain: C: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of a putative prephenate dehydrogenase (cgl0226)2 from corynebacterium glutamicum atcc 13032 at 2.60 a resolution
42d1qyca_



not modelled 97.0 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
43c1e5lA_



not modelled 97.0 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine reductase;
PDBTitle: apo saccharopine reductase from magnaporthe grisea
44d2jfga1



not modelled 96.9 13 Fold:MurCD N-terminal domain
Superfamily:MurCD N-terminal domain
Family:MurCD N-terminal domain
45c2axqA_



not modelled 96.9 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:saccharopine dehydrogenase;
PDBTitle: apo histidine-tagged saccharopine dehydrogenase (l-glu2 forming) from saccharomyces cerevisiae
46c3orqA_



not modelled 96.9 16 PDB header:ligase,biosynthetic protein
Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide synthetase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthetase from2 staphylococcus aureus complexed with adp
47d1qyda_



not modelled 96.9 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
48c1kyqC_



not modelled 96.8 13 PDB header:oxidoreductase, lyase
Chain: C: PDB Molecule:siroheme biosynthesis protein met8;
PDBTitle: met8p: a bifunctional nad-dependent dehydrogenase and2 ferrochelatase involved in siroheme synthesis.
49d1n7ha_



not modelled 96.8 14 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
50c2c20D_



not modelled 96.7 20 PDB header:isomerase
Chain: D: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of udp-glucose 4-epimerase
51d1pjca1



not modelled 96.7 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Formate/glycerate dehydrogenases, NAD-domain
52c2iz1C_



not modelled 96.7 13 PDB header:oxidoreductase
Chain: C: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: 6pdh complexed with pex inhibitor synchrotron data
53c3dhyC_



not modelled 96.7 13 PDB header:hydrolase
Chain: C: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structures of mycobacterium tuberculosis s-adenosyl-l-2 homocysteine hydrolase in ternary complex with substrate and3 inhibitors
54c1kjjA_



not modelled 96.7 8 PDB header:transferase
Chain: A: PDB Molecule:phosphoribosylglycinamide formyltransferase 2;
PDBTitle: crystal structure of glycniamide ribonucleotide2 transformylase in complex with mg-atp-gamma-s
55c1pjtB_



not modelled 96.6 20 PDB header:transferase/oxidoreductase/lyase
Chain: B: PDB Molecule:siroheme synthase;
PDBTitle: the structure of the ser128ala point-mutant variant of cysg,2 the multifunctional3 methyltransferase/dehydrogenase/ferrochelatase for4 siroheme synthesis
56c2zcuA_



not modelled 96.6 18 PDB header:oxidoreductase
Chain: A: PDB Molecule:uncharacterized oxidoreductase ytfg;
PDBTitle: crystal structure of a new type of nadph-dependent quinone2 oxidoreductase (qor2) from escherichia coli
57c3q2oB_



not modelled 96.6 9 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide2 synthetase
58c3on5B_



not modelled 96.6 18 PDB header:oxidoreductase
Chain: B: PDB Molecule:bh1974 protein;
PDBTitle: crystal structure of a xanthine dehydrogenase (bh1974) from bacillus2 halodurans at 2.80 a resolution
59c2pv7B_



not modelled 96.6 7 PDB header:isomerase, oxidoreductase
Chain: B: PDB Molecule:t-protein [includes: chorismate mutase (ec 5.4.99.5) (cm)
PDBTitle: crystal structure of chorismate mutase / prephenate dehydrogenase2 (tyra) (1574749) from haemophilus influenzae rd at 2.00 a resolution
60c3c1oA_



not modelled 96.6 8 PDB header:oxidoreductase
Chain: A: PDB Molecule:eugenol synthase;
PDBTitle: the multiple phenylpropene synthases in both clarkia2 breweri and petunia hybrida represent two distinct lineages
61c3i5mA_



not modelled 96.6 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:putative leucoanthocyanidin reductase 1;
PDBTitle: structure of the apo form of leucoanthocyanidin reductase from vitis2 vinifera
62c2x4gA_



not modelled 96.5 11 PDB header:isomerase
Chain: A: PDB Molecule:nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of pa4631, a nucleoside-diphosphate-sugar2 epimerase from pseudomonas aeruginosa
63c2vrcD_



not modelled 96.5 22 PDB header:oxidoreductase
Chain: D: PDB Molecule:triphenylmethane reductase;
PDBTitle: crystal structure of the citrobacter sp. triphenylmethane2 reductase complexed with nadp(h)
64c3dfzB_



not modelled 96.4 21 PDB header:oxidoreductase
Chain: B: PDB Molecule:precorrin-2 dehydrogenase;
PDBTitle: sirc, precorrin-2 dehydrogenase
65d1ek6a_



not modelled 96.4 17 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
66c1pgjA_



not modelled 96.4 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:6-phosphogluconate dehydrogenase;
PDBTitle: x-ray structure of 6-phosphogluconate dehydrogenase from the protozoan2 parasite t. brucei
67c3oneA_



not modelled 96.4 15 PDB header:hydrolase/hydrolase substrate
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of lupinus luteus s-adenosyl-l-homocysteine2 hydrolase in complex with adenine
68c2gn9B_



not modelled 96.4 10 PDB header:lyase
Chain: B: PDB Molecule:udp-glcnac c6 dehydratase;
PDBTitle: crystal structure of udp-glcnac inverting 4,6-dehydratase in complex2 with nadp and udp-glc
69c3n58D_



not modelled 96.4 14 PDB header:hydrolase
Chain: D: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from brucella2 melitensis in ternary complex with nad and adenosine, orthorhombic3 form
70c3uvzB_



not modelled 96.3 14 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosylaminoimidazole carboxylase, atpase subunit;
PDBTitle: crystal structure of phosphoribosylaminoimidazole carboxylase, atpase2 subunit from burkholderia ambifaria
71d1bg6a2



not modelled 96.3 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
72d1t2aa_



not modelled 96.3 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
73c1t2aC_



not modelled 96.3 19 PDB header:structural genomics,lyase
Chain: C: PDB Molecule:gdp-mannose 4,6 dehydratase;
PDBTitle: crystal structure of human gdp-d-mannose 4,6-dehydratase
74d1i24a_



not modelled 96.3 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
75c2q1uA_



not modelled 96.3 16 PDB header:sugar binding protein
Chain: A: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmf in2 complex with nad+ and udp
76c2rirA_



not modelled 96.2 14 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase, a chain;
PDBTitle: crystal structure of dipicolinate synthase, a chain, from bacillus2 subtilis
77c2hg5D_



not modelled 96.2 23 PDB header:membrane protein
Chain: D: PDB Molecule:kcsa channel;
PDBTitle: cs+ complex of a k channel with an amide to ester substitution in the2 selectivity filter
78d1orra_



not modelled 96.2 19 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
79c3e48B_



not modelled 96.1 12 PDB header:structural genomics, unknown function
Chain: B: PDB Molecule:putative nucleoside-diphosphate-sugar epimerase;
PDBTitle: crystal structure of a nucleoside-diphosphate-sugar epimerase2 (sav0421) from staphylococcus aureus, northeast structural genomics3 consortium target zr319
80c2q1wC_



not modelled 96.1 16 PDB header:sugar binding protein
Chain: C: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme wbmh in2 complex with nad+
81c3ggpA_



not modelled 96.1 10 PDB header:oxidoreductase
Chain: A: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from a. aeolicus in2 complex with hydroxyphenyl propionate and nad+
82c1z7eC_



not modelled 96.1 11 PDB header:hydrolase
Chain: C: PDB Molecule:protein arna;
PDBTitle: crystal structure of full length arna
83c3k5iB_



not modelled 96.1 13 PDB header:lyase
Chain: B: PDB Molecule:phosphoribosyl-aminoimidazole carboxylase;
PDBTitle: crystal structure of n5-carboxyaminoimidazole synthase from2 aspergillus clavatus in complex with adp and 5-3 aminoimadazole ribonucleotide
84c2f1kD_



not modelled 96.1 15 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of synechocystis arogenate dehydrogenase
85d2f1ka2



not modelled 96.0 15 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
86d1kjqa2



not modelled 96.0 13 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
87d1rpna_



not modelled 96.0 16 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
88c3gpiA_



not modelled 96.0 13 PDB header:structural genomics, unknown function
Chain: A: PDB Molecule:nad-dependent epimerase/dehydratase;
PDBTitle: structure of putative nad-dependent epimerase/dehydratase2 from methylobacillus flagellatus
89d1ks9a2



not modelled 96.0 13 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
90c2exxB_



not modelled 96.0 21 PDB header:unknown function
Chain: B: PDB Molecule:hscarg protein;
PDBTitle: crystal structure of hscarg from homo sapiens in complex with nadp
91c3fwnB_



not modelled 96.0 16 PDB header:oxidoreductase
Chain: B: PDB Molecule:6-phosphogluconate dehydrogenase, decarboxylating;
PDBTitle: dimeric 6-phosphogluconate dehydrogenase complexed with 6-2 phosphogluconate and 2'-monophosphoadenosine-5'-diphosphate
92c3gvpB_



not modelled 96.0 17 PDB header:hydrolase
Chain: B: PDB Molecule:adenosylhomocysteinase 3;
PDBTitle: human sahh-like domain of human adenosylhomocysteinase 3
93c3enkB_



not modelled 95.9 21 PDB header:isomerase
Chain: B: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: 1.9a crystal structure of udp-glucose 4-epimerase from2 burkholderia pseudomallei
94d1np3a2



not modelled 95.9 12 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
95d1wvga1



not modelled 95.9 20 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
96d1pgja2



not modelled 95.9 11 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
97d1z45a2



not modelled 95.8 18 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
98c2pzlB_



not modelled 95.8 22 PDB header:sugar binding protein
Chain: B: PDB Molecule:putative nucleotide sugar epimerase/ dehydratase;
PDBTitle: crystal structure of the bordetella bronchiseptica enzyme2 wbmg in complex with nad and udp
99c3slgB_



not modelled 95.8 11 PDB header:transferase
Chain: B: PDB Molecule:pbgp3 protein;
PDBTitle: crystal structure of pbgp3 protein from burkholderia pseudomallei
100c1np3B_



not modelled 95.8 13 PDB header:oxidoreductase
Chain: B: PDB Molecule:ketol-acid reductoisomerase;
PDBTitle: crystal structure of class i acetohydroxy acid isomeroreductase from2 pseudomonas aeruginosa
101d1bxka_



not modelled 95.8 9 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
102c1v8bA_



not modelled 95.8 10 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of a hydrolase
103c1n7gB_



not modelled 95.8 12 PDB header:lyase
Chain: B: PDB Molecule:gdp-d-mannose-4,6-dehydratase;
PDBTitle: crystal structure of the gdp-mannose 4,6-dehydratase2 ternary complex with nadph and gdp-rhamnose.
104c1luaA_



not modelled 95.8 11 PDB header:oxidoreductase
Chain: A: PDB Molecule:methylene tetrahydromethanopterin dehydrogenase;
PDBTitle: structure of methylene-tetrahydromethanopterin dehydrogenase from2 methylobacterium extorquens am1 complexed with nadp
105c3triB_



not modelled 95.8 12 PDB header:oxidoreductase
Chain: B: PDB Molecule:pyrroline-5-carboxylate reductase;
PDBTitle: structure of a pyrroline-5-carboxylate reductase (proc) from coxiella2 burnetii
106c2dwcB_



not modelled 95.8 13 PDB header:transferase
Chain: B: PDB Molecule:433aa long hypothetical phosphoribosylglycinamide formyl
PDBTitle: crystal structure of probable phosphoribosylglycinamide formyl2 transferase from pyrococcus horikoshii ot3 complexed with adp
107c3d64A_



not modelled 95.8 15 PDB header:hydrolase
Chain: A: PDB Molecule:adenosylhomocysteinase;
PDBTitle: crystal structure of s-adenosyl-l-homocysteine hydrolase from2 burkholderia pseudomallei
108c2g5cD_



not modelled 95.8 10 PDB header:oxidoreductase
Chain: D: PDB Molecule:prephenate dehydrogenase;
PDBTitle: crystal structure of prephenate dehydrogenase from aquifex aeolicus
109d1udca_



not modelled 95.7 24 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
110d2pv7a2



not modelled 95.7 7 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:6-phosphogluconate dehydrogenase-like, N-terminal domain
111c2pk3B_



not modelled 95.7 22 PDB header:oxidoreductase
Chain: B: PDB Molecule:gdp-6-deoxy-d-lyxo-4-hexulose reductase;
PDBTitle: crystal structure of a gdp-4-keto-6-deoxy-d-mannose reductase
112c1z45A_



not modelled 95.7 20 PDB header:isomerase
Chain: A: PDB Molecule:gal10 bifunctional protein;
PDBTitle: crystal structure of the gal10 fusion protein galactose2 mutarotase/udp-galactose 4-epimerase from saccharomyces3 cerevisiae complexed with nad, udp-glucose, and galactose
113c3dqpA_



not modelled 95.7 13 PDB header:oxidoreductase
Chain: A: PDB Molecule:oxidoreductase ylbe;
PDBTitle: crystal structure of the oxidoreductase ylbe from2 lactococcus lactis, northeast structural genomics3 consortium target kr121.
114d1kewa_



not modelled 95.6 10 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
115c3d4oA_



not modelled 95.6 15 PDB header:oxidoreductase
Chain: A: PDB Molecule:dipicolinate synthase subunit a;
PDBTitle: crystal structure of dipicolinate synthase subunit a (np_243269.1)2 from bacillus halodurans at 2.10 a resolution
116c2ph5A_



not modelled 95.6 10 PDB header:transferase
Chain: A: PDB Molecule:homospermidine synthase;
PDBTitle: crystal structure of the homospermidine synthase hss from legionella2 pneumophila in complex with nad, northeast structural genomics target3 lgr54
117d1a9xa4



not modelled 95.6 11 Fold:PreATP-grasp domain
Superfamily:PreATP-grasp domain
Family:BC N-terminal domain-like
118c2p5uC_



not modelled 95.6 17 PDB header:isomerase
Chain: C: PDB Molecule:udp-glucose 4-epimerase;
PDBTitle: crystal structure of thermus thermophilus hb8 udp-glucose 4-2 epimerase complex with nad
119d1oc2a_



not modelled 95.6 25 Fold:NAD(P)-binding Rossmann-fold domains
Superfamily:NAD(P)-binding Rossmann-fold domains
Family:Tyrosine-dependent oxidoreductases
120c1gpjA_



not modelled 95.6 17 PDB header:reductase
Chain: A: PDB Molecule:glutamyl-trna reductase;
PDBTitle: glutamyl-trna reductase from methanopyrus kandleri

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0