Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	D	W	L	L	D	V	F	A	T	W	L	Y	G	L	K	V	I	A	I	T	L	A	V	I	M	F	I	S	G	L	D	D	F	F	I	D	V	V	Y	W	V	R	R	I	K	R	K	L	S	V	Y	R	R	Y	P	R	M	S	Y
Secondary structure
SS confidence
Disorder		?	?																																																?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		R	E	L	Y	K	P	D	E	K	P	L	A	I	M	V	P	A	W	N	E	T	G	V	I	G	N	M	A	E	L	A	A	T	T	L	D	Y	E	N	Y	H	I	F	V	G	T	Y	P	N	D	P	D	T	Q	R	D	V	D	E	V
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		C	A	R	F	P	N	V	H	K	V	V	C	A	R	P	G	P	T	S	K	A	D	C	L	N	N	V	L	D	A	I	T	Q	F	E	R	S	A	N	F	A	F	A	G	F	I	L	H	D	A	E	D	V	I	S	P	M	E	L	R
Secondary structure
SS confidence
Disorder																		?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		L	F	N	Y	L	V	E	R	K	D	L	I	Q	I	P	V	Y	P	F	E	R	E	W	T	H	F	T	S	M	T	Y	I	D	E	F	S	E	L	H	G	K	D	V	P	V	R	E	A	L	A	G	Q	V	P	S	A	G	V	G	T
Secondary structure
SS confidence
Disorder																								?																											?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		C	F	S	R	R	A	V	T	A	L	L	A	D	G	D	G	I	A	F	D	V	Q	S	L	T	E	D	Y	D	I	G	F	R	L	K	E	K	G	M	T	E	I	F	V	R	F	P	V	V	D	E	A	K	E	R	E	Q	R	K	F
Secondary structure
SS confidence
Disorder														?	?	?	?																																						?	?	?		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		L	Q	H	A	R	T	S	N	M	I	C	V	R	E	Y	F	P	D	T	F	S	T	A	V	R	Q	K	S	R	W	I	I	G	I	V	F	Q	G	F	K	T	H	K	W	T	S	S	L	T	L	N	Y	F	L	W	R	D	R	K	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?																																			?	?	?	?	?		?	?	?							?
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		A	I	S	N	F	V	S	F	L	A	M	L	V	M	I	Q	L	L	L	L	L	A	Y	E	S	L	W	P	D	A	W	H	F	L	S	I	F	S	G	S	A	W	L	M	T	L	L	W	L	N	F	G	L	M	V	N	R	I	V	Q
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		R	V	I	F	V	T	G	Y	Y	G	L	T	Q	G	L	L	S	V	L	R	L	F	W	G	N	L	I	N	F	M	A	N	W	R	A	L	K	Q	V	L	Q	H	G	D	P	R	R	V	A	W	D	K	T	T	H	D	F	P	S	V
Secondary structure
SS confidence
Disorder																																											?	?		?	?	?	?		?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		T	G	D	T	R	S	L	R	P	L	G	Q	I	L	L	E	N	Q	V	I	T	E	E	Q	L	D	T	A	L	R	N	R	V	E	G	L	R	L	G	G	S	M	L	M	Q	G	L	I	S	A	E	Q	L	A	Q	A	L	A	E	Q
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?																										?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		N	G	V	A	W	E	S	I	D	A	W	Q	I	P	S	S	L	I	A	E	M	P	A	S	V	A	L	H	Y	A	V	L	P	L	R	L	E	N	D	E	L	I	V	G	S	E	D	G	I	D	P	V	S	L	A	A	L	T	R	K
Secondary structure
SS confidence
Disorder														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		V	G	R	K	V	R	Y	V	I	V	L	R	G	Q	I	V	T	G	L	R	H	W	Y	A	R	R	R	G	H	D	P	R	A	M	L	Y	N	A	V	Q	H	Q	W	L	T	E	Q	Q	A	G	E	I	W	R	Q	Y	V	P	H	Q
Secondary structure
SS confidence
Disorder																											?	?	?	?	?	?					?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720
Sequence		F	L	F	A	E	I	L	T	T	L	G	H	I	N	R	S	A	I	N	V	L	L	L	R	H	E	R	S	S	L	P	L	G	K	F	L	V	T	E	G	V	I	S	Q	E	T	L	D	R	V	L	T	I	Q	R	E	L	Q	V	S
Secondary structure
SS confidence
Disorder																								?	?	?	?	?	?	?																					?		?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.
Sequence		M	Q	S	L	L	L	K	A	G	L	N	T	E	Q	V	A	Q	L	E	S	E	N	E	G	E
Secondary structure
SS confidence
Disorder																	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2d28 chain C domain 1 Region: 484 - 624 Aligned: 139 Modelled: 141 Confidence: 100.0% Identity: 18% Fold: Alpha-lytic protease prodomain-like Superfamily: EspE N-terminal domain-like Family: GSPII protein E N-terminal domain-like Phyre2 PDB 3f1y chain C Region: 69 - 346 Aligned: 232 Modelled: 246 Confidence: 100.0% Identity: 14% PDB header:transferase Chain: C: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: mannosyl-3-phosphoglycerate synthase from rubrobacter xylanophilus Phyre2 PDB 1xhb chain A Region: 54 - 290 Aligned: 220 Modelled: 228 Confidence: 99.9% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 1; PDBTitle: the crystal structure of udp-galnac: polypeptide alpha-n-2 acetylgalactosaminyltransferase-t1 Phyre2 PDB 1xhb chain A domain 2 Region: 53 - 290 Aligned: 222 Modelled: 229 Confidence: 99.9% Identity: 14% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Polypeptide N-acetylgalactosaminyltransferase 1, N-terminal domain Phyre2 PDB 2z86 chain D Region: 62 - 327 Aligned: 225 Modelled: 234 Confidence: 99.9% Identity: 20% PDB header:transferase Chain: D: PDB Molecule:chondroitin synthase; PDBTitle: crystal structure of chondroitin polymerase from2 escherichia coli strain k4 (k4cp) complexed with udp-glcua3 and udp Phyre2 PDB 2d7i chain A Region: 65 - 290 Aligned: 208 Modelled: 217 Confidence: 99.9% Identity: 14% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 10; PDBTitle: crsytal structure of pp-galnac-t10 with udp, galnac and mn2+ Phyre2 PDB 2ffu chain A Region: 55 - 289 Aligned: 208 Modelled: 221 Confidence: 99.9% Identity: 12% PDB header:transferase Chain: A: PDB Molecule:polypeptide n-acetylgalactosaminyltransferase 2; PDBTitle: crystal structure of human ppgalnact-2 complexed with udp2 and ea2 Phyre2 PDB 3ckv chain A Region: 66 - 290 Aligned: 196 Modelled: 225 Confidence: 99.9% Identity: 15% PDB header:unknown function Chain: A: PDB Molecule:putative uncharacterized protein; PDBTitle: crystal structure of a mycobacterial protein Phyre2 PDB 3bcv chain A Region: 69 - 285 Aligned: 192 Modelled: 208 Confidence: 99.9% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:putative glycosyltransferase protein; PDBTitle: crystal structure of a putative glycosyltransferase from bacteroides2 fragilis Phyre2 PDB 1qg8 chain A Region: 69 - 333 Aligned: 227 Modelled: 239 Confidence: 99.9% Identity: 8% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Spore coat polysaccharide biosynthesis protein SpsA Phyre2 PDB 1omx chain B Region: 69 - 334 Aligned: 211 Modelled: 239 Confidence: 99.8% Identity: 11% PDB header:transferase Chain: B: PDB Molecule:alpha-1,4-n-acetylhexosaminyltransferase extl2; PDBTitle: crystal structure of mouse alpha-1,4-n-2 acetylhexosaminyltransferase (extl2) Phyre2 PDB 1omz chain A Region: 69 - 199 Aligned: 117 Modelled: 131 Confidence: 99.8% Identity: 12% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: Exostosin Phyre2 PDB 2qgi chain A Region: 75 - 289 Aligned: 191 Modelled: 215 Confidence: 99.6% Identity: 11% PDB header:transferase Chain: A: PDB Molecule:atp synthase subunits region orf 6; PDBTitle: the udp complex structure of the sixth gene product of the f1-atpase2 operon of rhodobacter blasticus Phyre2 PDB 2bo4 chain A domain 1 Region: 73 - 281 Aligned: 184 Modelled: 200 Confidence: 99.3% Identity: 17% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: MGS-like Phyre2 PDB 1pzt chain A Region: 60 - 281 Aligned: 157 Modelled: 168 Confidence: 98.6% Identity: 18% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: beta 1,4 galactosyltransferase (b4GalT1) Phyre2 PDB 3lw6 chain A Region: 70 - 281 Aligned: 145 Modelled: 159 Confidence: 98.2% Identity: 16% PDB header:transferase Chain: A: PDB Molecule:beta-4-galactosyltransferase 7; PDBTitle: crystal structure of drosophila beta1,4-galactosyltransferase-7 Phyre2 PDB 1fo8 chain A Region: 69 - 194 Aligned: 124 Modelled: 126 Confidence: 97.8% Identity: 8% Fold: Nucleotide-diphospho-sugar transferases Superfamily: Nucleotide-diphospho-sugar transferases Family: N-acetylglucosaminyltransferase I Phyre2 PDB 1p9r chain A Region: 652 - 745 Aligned: 82 Modelled: 94 Confidence: 97.0% Identity: 20% Fold: P-loop containing nucleoside triphosphate hydrolases Superfamily: P-loop containing nucleoside triphosphate hydrolases Family: RecA protein-like (ATPase-domain) Phyre2 PDB 2wvm chain A Region: 68 - 174 Aligned: 96 Modelled: 107 Confidence: 95.1% Identity: 21% PDB header:transferase Chain: A: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: h309a mutant of mannosyl-3-phosphoglycerate synthase from2 thermus thermophilus hb27 in complex with3 gdp-alpha-d-mannose and mg(ii) Phyre2 PDB 2zu8 chain A Region: 68 - 174 Aligned: 98 Modelled: 106 Confidence: 94.1% Identity: 13% PDB header:transferase Chain: A: PDB Molecule:mannosyl-3-phosphoglycerate synthase; PDBTitle: crystal structure of mannosyl-3-phosphoglycerate synthase2 from pyrococcus horikoshii Phyre2 PDB 2ch4 chain A Region: 604 - 734 Aligned: 127 Modelled: 127 Confidence: 89.1% Identity: 10% PDB header:transferase/chemotaxis Chain: A: PDB Molecule:chemotaxis protein chea; PDBTitle: complex between bacterial chemotaxis histidine kinase chea2 domains p4 and p5 and receptor-adaptor protein chew Phyre2 PDB 1ugp chain A Region: 472 - 538 Aligned: 65 Modelled: 65 Confidence: 68.3% Identity: 18% Fold: Nitrile hydratase alpha chain Superfamily: Nitrile hydratase alpha chain Family: Nitrile hydratase alpha chain Phyre2 1 d2d28c1 2 c3f1yC_ 3 c1xhbA_ 4 d1xhba2 5 c2z86D_ 6 c2d7iA_ 7 c2ffuA_ 8 c3ckvA_ 9 c3bcvA_ 10 d1qg8a_ 11 c1omxB_ 12 d1omza_ 13 c2qgiA_ 14 d2bo4a1 15 d1pzta_ 16 c3lw6A_ 17 d1fo8a_ 18 d1p9ra_ 19 c2wvmA_ 20 c2zu8A_ 21 22 23 c2ch4A_ 24 25 d1ugpa_ 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99